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https://www.readbyqxmd.com/read/28644135/evaluation-of-thromboelastometry-parameters-as-predictive-markers-for-sinusoidal-obstruction-syndrome-in-patients-undergoing-allogeneic-stem-cell-transplantation-for-acute-leukaemia
#1
Joanna Rupa-Matysek, Lidia Gil, Ewelina Wojtasińska, Zuzanna Kanduła, Adam Nowicki, Magdalena Matuszak, Mieczysław Komarnicki
Hepatic sinusoidal obstruction syndrome (previously named veno-occlusive disease, SOS/VOD) is a serious complication of allogeneic stem cell transplantation (HSCT). Early identification of patients at risk of SOS/VOD may possibly improve the outcome and reduce mortality. Rotation thromboelastometry (ROTEM) is global assay allowing for the precise assessment of both bleeding and thrombotic conditions, however, its usefulness in patients undergoing HSCT for acute leukaemia has not been studied.We evaluated the thromboelastometry parameters in patients undergoing allogeneic HSCT for acute leukaemia to identify candidate biomarkers of SOS/VOD occurrence...
June 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28604558/generating-actigraph-counts-from-raw-acceleration-recorded-by-an-alternative-monitor
#2
Jan Christian Brønd, Lars Bo Andersen, Daniel Arvidsson
PURPOSE: To implement an aggregation method in Matlab for generating ActiGraph counts from raw acceleration recorded with an alternative accelerometer device and to investigate the validity of the method. METHODS: The aggregation method including the frequency band-pass filter was implemented and optimized based on standardized sinusoidal acceleration signals generated in Matlab and processed in the ActiLife software. Evaluating the validity of the aggregation method was approached using a mechanical setup and with a 24-hour free-living recording using a convenient sample of nine subjects...
June 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28562425/rotational-and-collic-vestibular-evoked-myogenic-potential-testing-in-normal-developing-children-and-children-with-combined-attention-deficit-hyperactivity-disorder
#3
Younes Lotfi, Nima Rezazadeh, Abdollah Moossavi, Hojjat Allah Haghgoo, Reza Rostami, Enayatollah Bakhshi, Faride Badfar, Sedigheh Farokhi Moghadam, Vahid Sadeghi-Firoozabadi, Yousef Khodabandelou
OBJECTIVES: Vestibular dysfunction in childhood can have a major effect on a child's developmental process. Balance function has been reported to be poorer in children with attention deficit and hyperactivity disorder (ADHD) than in their typically developing peers. Due to contradictory available evidence and the paucity of research on vestibular function specifically in children with combined ADHD (cADHD), we designed this aged-matched study to assess vestibular function in children with cADHD...
May 26, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28560014/the-spinner-illusion-more-dots-more-speed
#4
Hiroshi Ashida, Alan Ho, Akiyoshi Kitaoka, Stuart Anstis
The perceived speed of a ring of equally spaced dots moving around a circular path appears faster as the number of dots increases (Ho & Anstis, 2013, Best Illusion of the Year contest). We measured this "spinner" effect with radial sinusoidal gratings, using a 2AFC procedure where participants selected the faster one between two briefly presented gratings of different spatial frequencies (SFs) rotating at various angular speeds. Compared with the reference stimulus with 4 c/rev (0.64 c/rad), participants consistently overestimated the angular speed for test stimuli of higher radial SFs but underestimated that for a test stimulus of lower radial SFs...
May 2017: I-Perception
https://www.readbyqxmd.com/read/28530263/utricular-hypofunction-in-patients-with-type-2-diabetes-mellitus
#5
K Jáuregui-Renaud, C Aranda-Moreno, A Herrera-Rangel
The aim of this study was to assess the function of the utricle and horizontal semicircular canals in patients with type 2 diabetes mellitus receiving primary health care, with/without a history of falls. 101 patients with type 2 diabetes mellitus, 34 to 84 years old (26 with and 75 without a history of falls) and 51 healthy volunteers (40-83 years old) accepted to participate. They denied having a history of dizziness, vertigo, unsteadiness, hearing loss or neurological disorders. None of them were seeking care due to sensory or balance decline...
May 22, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28463302/co-axis-digital-holography-based-on-sinusoidal-phase-modulation-using-generalized-lock-in-detection
#6
Yunlong Zhu, Julien Vaillant, Manuel François, Guillaume Montay, Aurélien Bruyant
Sinusoidal phase modulating (SPM) interferometers are used to precisely measure complex light fields with simple interferometric setups. Recently, a generalized lock-in technique has been proposed for optimizing the signal extraction in phase-modulated interferometers. This article shows its applicability in digital holography as well as digital holographic interferometry. A compact homemade setup based on the Michelson interferometer was used to observe the scattering sample surface with a spatial resolution of 32 LP/mm; out-of-plane rotation was measured with a theoretical detection limit of 0...
May 1, 2017: Applied Optics
https://www.readbyqxmd.com/read/28457586/adaptation-of-the-vertical-vestibulo-ocular-reflex-in-cats-during-low-frequency-vertical-rotation
#7
Hiroaki Fushiki, Motoyoshi Maruyama, Hideo Shojaku
OBJECTIVE: We examined plastic changes in the vestibulo-ocular reflex (VOR) during low-frequency vertical head rotation, a condition under which otolith inputs from the vestibular system are essential for VOR generation. METHODS: For adaptive conditioning of the vertical VOR, 0.02Hz sinusoidal pitch rotation for one hour about the earth's horizontal axis was synchronized with out-of-phase vertical visual stimulation from a random dot pattern. RESULTS: A vertical VOR was well evoked when the upright animal rotated around the earth-horizontal axis (EHA) at low frequency due to the changing gravity stimulus and dynamic stimulation of the otoliths...
April 27, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28455665/cross-coupling-vestibular-stimulation-motion-sickness-and-the-vestibulo-sympathetic-reflex
#8
Fausto Romano, Nicoletta Caramia, Dominik Straumann, Eugene Nalivaiko, Giovanni Bertolini
Motion sickness is associated with a variety of autonomic symptoms, presumably due to proximity or functional interconnectivity between the autonomic centers in the brainstem and the vestibular system. A direct influence of the vestibular system on cardiovascular variables, defined as the vestibulo-sympathetic reflex, has been reported previously. Our aim was to investigate the sudomotor components of the autonomic responses associated with motion sickness during passive cross-coupling stimulation ("roll while rotating")...
April 28, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28417834/adaptive-changes-in-the-perception-of-fast-and-slow-movement-at-different-head-positions
#9
Roberto Panichi, Chiara Occhigrossi, Aldo Ferraresi, Mario Faralli, Marco Lucertini, Vito E Pettorossi
BACKGROUND: This paper examines the subjective sense of orientation during asymmetric body rotations in normal subjects. METHODS: Self-motion perception was investigated in 10 healthy individuals during asymmetric whole-body rotation with different head orientations. Both on-vertical axis and off-vertical axis rotations were employed. Subjects tracked a remembered earth-fixed visual target while rotating in the dark for four cycles of asymmetric rotation (two half-sinusoidal cycles of the same amplitude, but of different duration)...
May 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28396602/nanoplasmonic-upconverting-nanoparticles-as-orientation-sensors-for-single-particle-microscopy
#10
Kory K Green, Janina Wirth, Shuang F Lim
We showed that the anisotropic disk shape of nanoplasmonic upconverting nanoparticles (NP-UCNPs) creates changes in fluorescence intensity during rotational motion. We determined the orientation by a three-fold change in fluorescence intensity. We further found that the luminescence intensity was strongly dependent on the particle orientation and on polarization of the excitation light. The luminescence intensity showed a three-fold difference between flat and on-edge orientations. The intensity also varied sinusoidally with the polarization of the incident light, with an Imax/Imin ratio of up to 2...
April 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28291198/-clinical-results-of-aphakia-correction-with-multifocal-intraocular-lenses
#11
G V Voronin, V R Mamikonyan, V M Sheludchenko, M N Narbut
AIM: to assess visual functions and ergonomics after bilateral versus unilateral implantation of Lentis Comfort LS-313 MF15 multifocal intraocular lenses (MIOL) in aphakic eyes. MATERIAL AND METHODS: A total of 20 patients with М LENTIS LS-313 MF15 MIOLs were followed up. Group 1 consisted of 12 patients after bilateral symmetric implantation, group 2 - of 8 patients after unilateral procedure. The following parameters were examined: uncorrected binocular visual acuity at far, near, and intermediate distances under photopic and mesopic conditions, the range of pseudoaccommodation, spatial contrast sensitivity to achromatic sinusoidal gratings, lens stability with account to its optical design, and patient satisfaction with the resultant vision...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28269379/energy-harvesting-from-human-walking-to-power-biomedical-devices-using-oscillating-generation
#12
Jose A Montoya, Dulce M Mariscal, Edwar Romero
This work summarizes the energy generation limits from walking employing a pendulum-based generation system. Self-winding wristwatches have exploited successfully this energy input technique for decades. Pendulum-based planar devices use the rotation to produce energy for inertial generators. Then the oscillations of body motion during locomotion present an opportunity to extract kinetic energy from planar generators. The sinusoidal motion of the center of gravity of the body, on the sagittal and frontal planes, and the limbs swinging are compliant with oscillating devices...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28249502/a-novel-cmos-transducer-for-giant-magnetoresistance-sensors
#13
Van Su Luong, Chih-Cheng Lu, Jing-Wen Yang, Jen-Tzong Jeng
In this work, an ASIC (application specific integrated circuits) transducer circuit for field modulated giant magnetoresistance (GMR) sensors was designed and fabricated using a 0.18-μm CMOS process. The transducer circuits consist of a frequency divider, a digital phase shifter, an instrument amplifier, and an analog mixer. These comprise a mix of analog and digital circuit techniques. The compact chip size of 1.5 mm × 1.5 mm for both analog and digital parts was achieved using the TSMC18 1P6M (1-polysilicon 6-metal) process design kit, and the characteristics of the system were simulated using an HSpice simulator...
February 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28227622/energy-harvesting-from-human-walking-to-power-biomedical-devices-using-oscillating-generation
#14
Jose A Montoya, Dulce M Mariscal, Edwar Romero, Jose A Montoya, Dulce M Mariscal, Edwar Romero, Dulce M Mariscal, Jose A Montoya, Edwar Romero
This work summarizes the energy generation limits from walking employing a pendulum-based generation system. Self-winding wristwatches have exploited successfully this energy input technique for decades. Pendulum-based planar devices use the rotation to produce energy for inertial generators. Then the oscillations of body motion during locomotion present an opportunity to extract kinetic energy from planar generators. The sinusoidal motion of the center of gravity of the body, on the sagittal and frontal planes, and the limbs swinging are compliant with oscillating devices...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28190505/thoracolumbar-movement-in-sound-horses-trotting-in-straight-lines-in-hand-and-on-the-lunge-and-the-relationship-with-hind-limb-symmetry-or-asymmetry
#15
L Greve, T Pfau, S Dyson
Equine movement symmetry is changed when turning, which may induce alterations in thoracolumbosacral kinematics; however, this has not previously been investigated. Our objectives were to document thoracolumbar movement in subjectively sound horses comparing straight lines with circles on both reins and to relate these observations to the objectively determined symmetry/asymmetry of hindlimb gait. Fourteen non-lame horses were assessed prospectively in a non-random, cross-sectional survey. The horses were trotted in straight lines and lunged on both reins and inertial sensor data collected at landmarks: withers, T13 and T18, L3, tubera sacrale, and left and right tubera coxae...
February 2017: Veterinary Journal
https://www.readbyqxmd.com/read/28176802/ocular-reflex-phase-during-off-vertical-axis-rotation-in-humans-is-modified-by-head-turn-on-trunk-position
#16
Samantha B Douglas, Gilles Clément, Pierre Denise, Scott J Wood
Constant velocity Off-Vertical Axis Rotation (OVAR) imposes a continuously varying orientation of the head and body relative to gravity, which generates a modulation of horizontal (conjugate and vergence), vertical, and torsional eye movements. We introduced the head-turn-on-trunk paradigm during OVAR to examine the extent to whether the modulation of these ocular reflexes is mediated by graviceptors in the head, i.e., otoliths, versus other body graviceptors. Ten human subjects were rotated in darkness about their longitudinal axis 20° off-vertical at a constant velocity of 45 and 180°/s, corresponding to 0...
February 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28125681/accumulation-of-inertial-sensory-information-in-the-perception-of-whole-body-yaw-rotation
#17
Alessandro Nesti, Ksander de Winkel, Heinrich H Bülthoff
While moving through the environment, our central nervous system accumulates sensory information over time to provide an estimate of our self-motion, allowing for completing crucial tasks such as maintaining balance. However, little is known on how the duration of the motion stimuli influences our performances in a self-motion discrimination task. Here we study the human ability to discriminate intensities of sinusoidal (0.5 Hz) self-rotations around the vertical axis (yaw) for four different stimulus durations (1, 2, 3 and 5 s) in darkness...
2017: PloS One
https://www.readbyqxmd.com/read/28077670/the-mammalian-efferent-vestibular-system-plays-a-crucial-role-in-vestibulo-ocular-reflex-compensation-after-unilateral-labyrinthectomy
#18
Patrick P Hübner, Serajul I Khan, Americo A Migliaccio
The α9-nicotinic acetylcholine receptor (α9-nAChR) subunit is expressed in the vestibular and auditory periphery, and its loss of function could compromise peripheral input from the predominantly cholinergic efferent vestibular system (EVS). A recent study has shown that α9-nAChRs play an important role in short-term vestibulo-ocular reflex (VOR) adaptation. We hypothesize that α9-nAChRs could also be important for other forms of vestibular plasticity, such as that needed for VOR recovery after vestibular organ injury...
April 1, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28063365/aging-reduces-the-high-frequency-and-short-term-adaptation-of-the-vestibulo-ocular-reflex-in-mice
#19
Serajul I Khan, Patrick P Hübner, Alan M Brichta, Doug W Smith, Americo A Migliaccio
Prevailing evidence indicates a relatively late life decline in human vestibulo-ocular reflex (VOR) function. Although mice are commonly used in mechanistic studies of vestibular function, it remains unclear whether aging produces a corresponding decline in VOR function in mice. We sought to determine how the baseline VOR and its short-term adaptation were affected by aging. We tested 8 young (3-month old) and 8 aged (30-month old-equivalent to a ∼80-year old human) C57BL/6 mice. We measured their VOR response to whole-body static tilts and during 0...
March 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/28047059/th-cd-207a-06-optimizing-four-dimensional-digital-tomosynthesis-acquisition-based-on-respiratory-guidance
#20
D Kim, S Lee, S Kim, S Kang, T Kim, K Kim, M Cho, D Shin, Y Noh, T Suh
PURPOSE: Patient breathing-related sorting method of projections in 4D digital tomosythesis (DTS) can be suffered from severe artifacts due to non-uniform angle distribution of projections and noncoplanar reconstructed images for each phase. In this study, we propose a method for optimally acquiring projection images in 4D DTS. METHODS: In this method every pair of projections at x-ray tube's gantry angles symmetrical with respect to the center of the range of gantry rotation is obtained at the same respiration amplitude...
June 2016: Medical Physics
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