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Alexander Chow, B Sherer, E Yura, S Kielb, E Kocjancic, S Eggener, T Turk, S Park, S Psutka, M Abern, K Latchamsetty, C Coogan
OBJECTIVE: To evaluate the Urological resident's attitude and experience with surgical simulation in residency education using a multi-institutional, multi-modality model. MATERIALS AND METHODS: Residents from six area urology training programs rotated through simulation stations in four consecutive sessions from 2014 to 2017. Workshops included GreenLight photovaporization of the prostate(PVP), ureteroscopic stone extraction, laparoscopic peg transfer, 3-dimensional laparoscopy rope pass, transobturator sling placement, intravesical injection, high definition video system trainer (VITOM), vasectomy, and Urolift...
August 8, 2017: Urology
Claire Pascoe, Darren Ow, Marlon Perera, Henry H Woo, Greg Jack, Nathan Lawrentschuk
Benign prostatic hyperplasia (BPH) is a common pathology causing lower urinary tract symptoms (LUTS) and may significantly impact quality of life. While transurethral resection of the prostate (TURP) remains the gold standard treatment, there are many evolving technologies that are gaining popularity. Photoselective vaporization of the prostate (PVP) is one such therapy which has been shown to be non-inferior to TURP. We aimed to review the literature and discuss factors to optimise patient outcomes in the setting of PVP for BPH...
July 2017: Translational Andrology and Urology
Yoshiko Takeuchi, Rina Usui, Hidekazu Ikezaki, Kohei Tahara, Hirofumi Takeuchi
Taste detection systems using electronic sensors are needed in the field of pharmaceutical design. The aim of this study was to propose an advanced technique using a taste-sensing system to evaluate the bitterness of an orally disintegrating film (ODF) samples. In this system, a solid film sample is kept in the test medium with stirring, and the sensor output is recorded. Model films were prepared using a solution-casting method with a water-soluble polymer such as pullulan, HPMC, HPC or PVP as film formers, and donepezil hydrochloride and quinine hydrochloride as model bitter-tasting active pharmaceutical ingredients (APIs)...
August 5, 2017: International Journal of Pharmaceutics
Lilian H J Richter, Hans H Maurer, Markus R Meyer
New psychoactive substances (NPS) are an increasing problem in clinical and forensic toxicology. The knowledge of their metabolism is important for toxicological risk assessment and for developing toxicological urine screenings. Considering the huge numbers of NPS annually appearing on the market, metabolism studies should be realized in a fast, simple, cost efficient, and reliable way. Primary human hepatocytes (PHH) were recommended to be the gold standard for in vitro metabolism studies as they are expected to contain natural enzyme clusters, co-substrates, and drug transporters...
August 3, 2017: Toxicology Letters
Dong-Ho Kang, Woo-Young Choi, Hyunsuk Woo, Sungkyu Jang, Hyung-Youl Park, Jaewoo Shim, Jae-Woong Choi, Sungho Kim, Sanghun Jeon, Sungjoo Lee, Jin-Hong Park
In this study, we demonstrate a high-performance solid polymer electrolyte (SPE) atomic switching device with low SET/RESET voltages (0.25 and -0.5 V, respectively), high on/off-current ratio (10(5)), excellent cyclic endurance (>10(3)), and long retention time (>10(4) s), where poly-4-vinylphenol (PVP)/poly(melamine-co-formaldehyde) (PMF) is used as an SPE layer. To accomplish these excellent device performance parameters, we reduce the off-current level of the PVP/PMF atomic switching device by improving the electrical insulating property of the PVP/PMF electrolyte through adjustment of the number of cross-linked chains...
August 4, 2017: ACS Applied Materials & Interfaces
Siti Nurehan Abd Jalil, David K Wang, Christelle Yacou, Julius Motuzas, Simon Smart, João C Diniz da Costa
This work investigates the structural formation and analyses of titania membranes (TM) prepared using different vacuum exposure times for molecular weight (MW) cut-off performance and oil/water separation. Titania membranes were synthesized via a sol-gel method and coated on macroporous alumina tubes followed by exposure to a vacuum between 30 and 1200 s and then calcined at 400 °C. X-ray diffraction and nitrogen adsorption analyses showed that the crystallite size and particle size of titania increased as a function of vacuum time...
November 18, 2016: Materials
Hongliang Li, Hui Liu, Aiping Fu, Guanglei Wu, Man Xu, Guangsheng Pang, Peizhi Guo, Jingquan Liu, Xiu Song Zhao
Three kinds of N-doped mesoporous TiO₂ hollow spheres with different N-doping contents, surface area, and pore size distributions were prepared based on a sol-gel synthesis and combined with a calcination process. Melamine formaldehyde (MF) microspheres have been used as sacrificial template and cetyltrimethyl ammonium bromide (CTAB) or polyvinylpyrrolidone (PVP) was selected as pore-directing agent. Core-shell intermediate spheres of titania-coated MF with diameters of 1.2-1.6 μm were fabricated by varying the volume concentration of TiO₂ precursor from 1 to 3 vol %...
October 19, 2016: Materials
Andrea Pietro Reverberi, Marco Salerno, Simone Lauciello, Bruno Fabiano
Copper nanoparticles have been synthesized in ethylene glycol (EG) using copper sulphate as a precursor and vanadium sulfate as an atypical reductant being active at room temperature. We have described a technique for a relatively simple preparation of such a reagent, which has been electrolytically produced without using standard procedures requiring an inert atmosphere and a mercury cathode. Several stabilizing agents have been tested and cationic capping agents have been discarded owing to the formation of complex compounds with copper ions leading to insoluble phases contaminating the metallic nanoparticles...
September 29, 2016: Materials
Ching-Lin Fan, Ming-Chi Shang, Shea-Jue Wang, Mao-Yuan Hsia, Win-Der Lee, Bohr-Ran Huang
In this study, a proposed Microwave-Induction Heating (MIH) scheme has been systematically studied to acquire suitable MIH parameters including chamber pressure, microwave power and heating time. The proposed MIH means that the thin indium tin oxide (ITO) metal below the Poly(4-vinylphenol) (PVP) film is heated rapidly by microwave irradiation and the heated ITO metal gate can heat the PVP gate insulator, resulting in PVP cross-linking. It is found that the attenuation of the microwave energy decreases with the decreasing chamber pressure...
July 3, 2017: Materials
Toshio Itoh, Toshio Uchida, Noriya Izu, Woosuck Shin
We investigated the preparation of well-dispersed core-shell ceria-poly(vinylpyrrolidone) (PVP) nanoparticles with an average particle size of around 20 nm which were used to produce a hybrid film with a polymer coating of dipentaerythritol hexaacrylate (DPHA). We obtained good dispersion of the nanoparticles in a mixed solvent of 48% 1-methoxy-2-propanol (MP), 32% 3-methoxy-3-methyl-1-butanol (MMB), and 20% methyl i-butyl ketone (MIBK). An ink of the polymer coating consisting of 68.7 wt% nanoparticles and 31...
June 27, 2017: Materials
Jae Sang Heo, Seungbeom Choi, Jeong-Wan Jo, Jingu Kang, Ho-Hyun Park, Yong-Hoon Kim, Sung Kyu Park
In this paper, we demonstrate high mobility solution-processed metal-oxide thin-film transistors (TFTs) by using a high-frequency-stable ionic-type hybrid gate dielectric (HGD). The HGD gate dielectric, a blend of sol-gel aluminum oxide (AlOx) and poly(4-vinylphenol) (PVP), exhibited high dielectric constant (ε~8.15) and high-frequency-stable characteristics (1 MHz). Using the ionic-type HGD as a gate dielectric layer, an minimal electron-double-layer (EDL) can be formed at the gate dielectric/InOx interface, enhancing the field-effect mobility of the TFTs...
June 3, 2017: Materials
Xuan Xu, Shiyu Zhou, Jun Long, Tianhu Wu, Zihong Fan
In this paper, YF₃:Ho(3+)@TiO₂ core-shell nanomaterials were prepared by hydrolysis of tetra-n-butyl titanate (TBOT) using polyvinylpyrrolidone K-30 (PVP) as the coupling agent. Characterization methods including X-ray diffraction (XRD), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDS) under TEM, X-ray photoelectron spectroscopy (XPS), fluorescence spectrometry, ultraviolet-visible diffuse reflectance spectroscopy, and electron spin resonance (ESR) were used to characterize the properties and working mechanism of the prepared photocatalyst material...
March 16, 2017: Materials
Wei Long Ng, Wai Yee Yeong, May Win Naing
Drop-on-demand (DOD) bioprinting has attracted huge attention for numerous biological applications due to its precise control over material volume and deposition pattern in a contactless printing approach. 3D bioprinting is still an emerging field and more work is required to improve the viability and homogeneity of printed cells during the printing process. Here, a general purpose bio-ink was developed using polyvinylpyrrolidone (PVP) macromolecules. Different PVP-based bio-inks (0%-3% w/v) were prepared and evaluated for their printability; the short-term and long-term viability of the printed cells were first investigated...
February 16, 2017: Materials
Deqiang Zhao, Wenwen Wang, Wenjuan Zong, Shimin Xiong, Qian Zhang, Fangying Ji, Xuan Xu
The band gaps of bismuth vanadate (BiVO₄) and bismuth sulfide (Bi₂S₃) are about 2.40 eV and 1.30 eV, respectively. Although both BiVO₄ and Bi₂S₃ are capable of strong visible light absorption, electron-hole recombination occurs easily. To solve this problem, we designed a one-step hydrothermal method for synthesizing a Bismuth sulfide (Bi₂S₃)/Bismuth vanadate (BiVO₄) heterojunction using polyvinylpyrrolidone K-30 (PVP) as a structure-directing agent, and 2-Amino-3-mercaptopropanoic acid (l-cysteine) as a sulfur source...
August 2, 2017: Materials
Yan-Xiong Wu, Pei Liang, Qian-Min Dong, Yang Bai, Zhi Yu, Jie Huang, Yuan Zhong, Yu-Chan Dai, Dejiang Ni, Hai-Bo Shu, Charles U Pittman
Flower-shaped silver nanoparticles have been successfully synthesized by a simple aqueous phase silver nitrate reduction by ascorbic acid in the presence of polyvinylpyrrolidone (PVP) surfactant. The nanoparticles diameters were adjusted from 450 to 1000nm with surface protrusions up to 10-25nm. The growth direction of silver nuclei is controlled by their degree of coating by PVP. The flower-shaped silver nanostructures obtained were used as stable Surface Enhanced Raman Scattering (SERS) substrates with high SERS activity for detecting Rhodamine 6G (R6G), at a concentration of only 10(-9)M, where the SERS signal is still clear...
December 15, 2017: Food Chemistry
Majid Valizadeh, Pantea Nazeri, Farzaneh Fazli, Farnaz Mohammadian, Sadreddin Kalantari, Koorosh Kamali, Hesam Osali
BACKGROUND: The aim of the present study was to investigate the effect of povidone-iodine (PVP-I) application at delivery on maternal urinary iodine concentration (UIC) and neonatal thyrotropin concentration. METHODS: In this cross-sectional study, urine samples were collected from each pregnant woman after admission to the hospital and before routine application of the PVP-I for delivery preparation and after delivery at time of screening for congenital hypothyroidism...
August 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
Martha-Estrella García-Pérez, Zoe Lemus-Rodríguez, Mario Hung-Arbelo, Marlen Vistel-Vigo
PURPOSE: Petiveria alliacea L. (Phytolaccaceae) is a perennial shrub used by its immunomodulatory, anticancerogenic and anti-inflammatory properties. This study determined the influence of polyvinylpyrrolidone (PVP), colloidal silicon dioxide (CSD) and microcrystalline cellulose (MC) on the technological characteristic of a high-dose P.alliacea tablet prepared by the wet granulation method. METHODOLOGY: The botanical and pharmacognostic analysis of the plant material was firstly performed, followed by a 2(3) factorial design considering three factors at two levels: a) the binder (PVP) incorporated in formulation at 10 and 15% (w/w); b) the compacting agent (CSD) added at 10 and 15% (w/w) and; c) the diluent (MC) included at 7...
August 1, 2017: Drug Development and Industrial Pharmacy
Pawan Vasudeva, Niraj Kumar, Anup Kumar, Gaurav Kumar, Mikir Patel, Pankaj Gupta
OBJECTIVES: To compare monopolar transurethral resection of the prostate (TURP), bipolar TURP and photoselective vaporization of the prostate (PVP) by 120-W GreenLight laser with regard to the impact on International Index of Erectile Function (IIEF)-5 score in patients presenting with lower urinary tract symptoms (LUTS) secondary to prostate >80 mL. METHODS: Between April 2012 and March 2015, 110 patients who satisfied eligibility criteria were divided into three groups according to surgical modality adopted to treat benign prostatic enlargement...
August 1, 2017: Lower Urinary Tract Symptoms
Kamonwan Tangvoraphonkchai, Anne Riddell, Andrew Davenport
INTRODUCTION: Hemodialysis patients are pro-thrombotic. Higher volume online postdilutional hemodiafiltration (OL-HDF), with increasing hematocrit increases the risk of clotting in the extracorporeal circuit (ECC). We wished to determine whether OL-HDF increased platelet activation and ECC clotting. METHODS: Coagulation parameters, platelet, white cell, and endothelial activation markers were measured at the start and end of dialysis sessions in 10 patients and also pre- and post-dialyzer after 15 minutes using two different dialyzers designed for high volume OL-HDF; cellulose triacetate (TAGP) and polysulphone (PS), and polyvinylpyrrolidone (PVP)...
August 1, 2017: Hemodialysis International
T G Bergstein-Galan, L C Bicudo, L Rodello, R R Weiss, S D Bicudo
The aim of this study was to evaluate the effect of four methods of sperm selection, on the integrity and stability of the plasma membrane, integrity of the acrosomal membrane and spermatic morphology in frozen/thawed ovine semen. Two types of colloidal silica: colloidal silica-silane and colloidal silica-polyvinylpyrrolidone (PVP), and two aliquots: 1 and 4 ml, were used for sperm selection. Probes FITC-PSA and PI were used to measure the integrity of the plasma and acrosomal membranes. Plasma membrane stability was measured, using fluorescent probes M540 and YOPRO1...
July 31, 2017: Andrologia
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