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pediatric migraines

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https://www.readbyqxmd.com/read/28721545/is-topiramate-effective-for-migraine-prevention-in-patients-less-than-18%C3%A2-years-of-age-a-meta-analysis-of-randomized-controlled-trials
#1
REVIEW
Kai Le, Dafan Yu, Jiamin Wang, Abdoulaye Idriss Ali, Yijing Guo
BACKGROUND: Mainly based on evidence of success in adults, various medications are commonly used to prevent pediatric migraines. Topiramate has been approved for migraine prevention in children as young as 12 years of age. In this meta-analysis, we aimed to assess the currently published data pertaining to the efficacy of topiramate for migraine prevention in patients less than 18 years of age. METHODS: We searched PubMed/Medline, Embase and the Cochrane Library (from inception to April 2017) for randomized controlled trials (RCTs) published in English...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28701441/topiramate-for-pediatric-migraine-prevention
#2
Teeranai Sakulchit, Garth D Meckler, Ran D Goldman
Question I have several teenagers in my clinic with migraine headache and some of them have frequent episodes that cause considerable interference with daily activity. I would like to offer them prophylactic therapy to reduce the frequency of their migraine episodes. Is topiramate an effective and safe option for adolescents? Answer Both Health Canada and the US Food and Drug Administration have approved the use of topiramate for migraine prevention in adults; however, only the US Food and Drug Administration has approved topiramate for migraine prophylaxis in adolescents 12 to 17 years of age...
July 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28677996/headache-in-pediatric-and-adolescent-patients-with-chronic-kidney-disease-with-and-without-hemodialysis-a-comparative-cohort-study
#3
Miriam Davidovits, Tal Eidlitz Markus
Background Several studies have reported dialysis-related headache in adults. We investigated headache and its characteristics in pediatric and adolescent patients with chronic kidney disease and patients treated with dialysis, and compared characteristics of patients with and without headache in the entire cohort and separately among dialysis and among chronic kidney disease patients. Methods Patients and their parents who attended a nephrology clinic and hemodialysis unit were interviewed regarding the existence of headache and its characteristics...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28669082/accompanying-migrainous-features-in-pediatric-migraine-patients-with-restless-legs-syndrome
#4
Melis Sohtaoğlu Sevindik, Seden Demirci, Baki Göksan, Aynur Özge, Feray Karaali Savrun, Hatice Onur, Veli Yıldırım, Ismail Simsek, Harika Ozhan, Derya Uludüz
The present study aimed to examine the frequency of restless legs syndrome (RLS) in pediatric patients with migraine and tension-type headache (TTH) and to investigate accompanying migrainous symptoms, sleep characteristics, as well as levels of serum ferritin between the pediatric migraine patients with RLS and those without RLS. We included 65 consecutive patients diagnosed with migraine, 20 patients with TTH, and 97 headache-free children in our study. Demographic, clinical, and laboratory data were noted...
July 1, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28665241/shunt-dependent-hydrocephalus-management-style-among-members-of-the-american-society-of-pediatric-neurosurgeons
#5
Mark R Kraemer, Carolina Sandoval-Garcia, Taryn Bragg, Bermans J Iskandar
OBJECTIVE The authors conducted a survey to evaluate differences in the understanding and management of shunt-dependent hydrocephalus among members of the American Society of Pediatric Neurosurgeons (ASPN). METHODS Surveys were sent to all 204 active ASPN members in September 2014. One hundred thirty responses were received, representing a 64% response rate. Respondents were asked 13 multiple-choice and free-response questions regarding 4 fundamental problems encountered in shunted-hydrocephalus management: shunt malfunction, chronic cerebrospinal fluid (CSF) overdrainage, chronic headaches, and slit ventricle syndrome (SVS)...
June 30, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28648276/amitriptyline-and-topiramate-do-not-demonstrate-benefit-in-pediatric-migraine
#6
Saba Ahmad
No abstract text is available yet for this article.
July 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28628697/pediatric-migraine-prevention-first-do-no-harm
#7
Amy A Gelfand, William Qubty, Peter J Goadsby
No abstract text is available yet for this article.
June 19, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28612516/autonomic-nervous-system-function-in-adolescent-migraineurs
#8
Seiji Yoshida, Hidetaka Tanaka, Midori Mizutani, Ryota Nakao, Naoyuki Okamoto, Mitsugu Kajiura, Yukiko Kanbara, Hiroshi Tamai
BACKGROUND: Migraine is a common and disabling neurological disorder. Studies attempting to determine a relationship between migraine and the autonomic nervous system (ANS) have been inconclusive. Moreover, pediatric studies are extremely limited. Therefore, the present study investigated interictal ANS function in adolescent migraineurs. METHODS: We studied 21 patients with migraine and 26 healthy controls. Beat-to-beat blood pressure (BP) and heart rate (HR) were noninvasively and continuously measured in the supine and standing positions...
June 14, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28597113/headache-in-children-and-dynamic-thiol-disulfide-balance-evaluation-with-a-new-method
#9
Aysegül Nese Citak Kurt, Alperen Aydın, Hatice Demir, Özcan Erel
Headache is one of the most common causes of presentation to the physician in children. We aimed to evaluate the dynamic thiol/disulfide homeostasis with a new method in children with headache and also to investigate the relationship between the headache type, pain severity and duration in our study. We included 40 patients diagnosed with migraine, 40 patients diagnosed with tension-type headache (TTH) and 40 healthy children in the study. No significant difference was found between the total thiol, native thiol, and disulfide levels of the patient and control groups...
June 8, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28594121/a-review-of-vomiting-and-migraine-related-clinical-parameters-in-pediatric-migraine
#10
Lynda J Krasenbaum
No abstract text is available yet for this article.
June 2017: Headache
https://www.readbyqxmd.com/read/28587507/adhd-is-comorbid-to-migraine-in-childhood-a-population-based-study
#11
Marco Antônio Arruda, Renato Arruda, Vincenzo Guidetti, Marcelo Eduardo Bigal
OBJECTIVE: Recurrent headaches and ADHD are prevalent in the pediatric population. Herein, we assess if ADHD is comorbid to headaches overall, to headache subtypes (e.g., migraine), and to headache frequency. METHOD: Informed consent and analyzable data were obtained for 5,671 children aged 5 to 12 years (65.9% of the target sample). Parents and teachers were interviewed using validated questionnaires based on the Diagnostic and Statistical Manual of Mental Disorders (5th ed...
June 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28579749/comprehensive-review-of-visual-defects-reported-with-topiramate
#12
REVIEW
Lisa Ford, Jeffrey L Goldberg, Fred Selan, Howard E Greenberg, Yingqi Shi
OBJECTIVE: The objective of this study was to analyze clinical patterns of visual field defects (VFDs) reported with topiramate treatment and assess possible mechanism of action (MOA) for antiepileptic drug (AED) associated VFDs. METHODS: A comprehensive topiramate database review included preclinical data, sponsor's clinical trials database, postmarketing spontaneous reports, and medical literature. All treatment-emergent adverse events (TEAEs) suggestive of retinal dysfunction/damage were summarized...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28578816/characteristics-of-headaches-in-japanese-elementary-and-junior-high-school-students-a-school-based-questionnaire-survey
#13
Masahide Goto, Koji Yokoyama, Yasuyuki Nozaki, Koichi Itoh, Ryou Kawamata, Shizuko Matsumoto, Takanori Yamagata
PURPOSE: Few studies have investigated pediatric headaches in Japan. Thus, we examined the lifetime prevalence and characteristics of headaches among elementary and junior high school students in Japan. METHODS: In this school-based study, children aged 6-15years completed a questionnaire based on the diagnostic criteria of the International Classification of Headache Disorders-3β to assess headache characteristics and related disability. RESULTS: Of the 3285 respondents, 1623 (49...
May 31, 2017: Brain & Development
https://www.readbyqxmd.com/read/28560777/in-child-and-adult-migraineurs-the-somatosensory-cortex-stands-out-%C3%A2-again-an-arterial-spin-labeling-investigation
#14
Andrew M Youssef, Allison Ludwick, Sophie L Wilcox, Alyssa Lebel, Ke Peng, Elisabeth Colon, Amy Danehy, Rami Burstein, Lino Becerra, David Borsook
Over the past decade, human brain imaging investigations have reported altered regional cerebral blood flow (rCBF) in the interictal phase of migraine. However, there have been conflicting findings across different investigations, making the use of perfusion imaging in migraine pathophysiology more difficult to define. These inconsistencies may reflect technical constraints with traditional perfusion imaging methods such as single-photon emission computed tomography and positron emission tomography. Comparatively, pseudocontinuous arterial spin labeling (pCASL) is a recently developed magnetic resonance imaging technique that is noninvasive and offers superior spatial resolution and increased sensitivity...
August 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28527089/pediatric-migraine-with-aura-in-an-italian-case-series
#15
Arens Taga, Marco Russo, Antonio Genovese, Maria Vittoria Paglia, Gian Camillo Manzoni, Paola Torelli
The aim of the present study was to describe the characteristics of migraine with aura (MwA) in a case series of patients with headache onset before 12 years of age. We considered all consecutive patients referred to the Parma Headache Centre between 1975 and 2015 affected by MwA, diagnosed by our team of trained neurologists; the cases were subsequently reviewed applying the ICHD3-beta criteria. We then identified those cases with headache age-of-onset <12 years (i.e., "pediatric" cases), which were compared to all remaining cases...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28527061/ketogenic-diet-in-migraine-rationale-findings-and-perspectives
#16
Piero Barbanti, Luisa Fofi, Cinzia Aurilia, Gabriella Egeo, Massimiliano Caprio
Ketogenic diet (KD) is an established treatment for refractory pediatric epilepsy and a promising therapy for diverse neurological diseases. Clinical data on KD in migraine-obtained from 150 patients investigated in case reports and prospective studies-suggest that KD may be a rapid onset effective prophylaxis for episodic and chronic migraine. KD would contribute to restore brain excitability and metabolism and to counteract neuroinflammation in migraine, although its precise mechanism is still unclear. Randomized controlled studies are needed to confirm the usefulness of KD in migraine and to investigate its optimal duration, repeatability, feasibility in normal weight subjects, efficacy in pediatric population and association to conventional migraine prophylaxis...
May 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28507424/migraine-celiac-disease-and-intestinal-microbiota
#17
COMMENT
Hakim Rahmoune, Nada Boutrid
Investigators from four European tertiary care hospitals (in Paris, France; Milan, Udine and Perugia, Italy) performed a case-control study of children and adolescents aged 6 to 17 years diagnosed with primary headaches in the emergency department by a pediatric neurologist using the validated ICHD-3 criteria.
February 2017: Pediatric neurology briefs
https://www.readbyqxmd.com/read/28496528/long-term-study-of-children-with-rome-iii-functional-gastrointestinal-disorders-managed-symptomatically-in-a-biopsychosocial-model
#18
Shailender Madani, Suchi Parikh, Rohit S Madani, Amornluck Krasaelap
BACKGROUND: Our study evaluated progression of and identified potential factors contributing to outcomes of ROME III defined-functional gastrointestinal disorders (FGIDs) in children treated symptomatically in a biopsychosocial model of care with a long-term follow-up. METHODS: We performed a retrospective review of pediatric patients who were diagnosed with ROME III defined-FGIDs including functional abdominal pain, functional dyspepsia, irritable bowel syndrome and abdominal migraine...
April 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28480554/vomiting-and-migraine-related-clinical-parameters-in-pediatric-migraine
#19
Tal Eidlitz-Markus, Yishai Haimi-Cohen, Avraham Zeharia
OBJECTIVE/BACKGROUND: To investigate the characteristics of vomiting in pediatric migraineurs and the relationship of vomiting with other migraine-related parameters. METHODS: The cohort included children and adolescents with migraine attending a headache clinic of a tertiary pediatric medical center from 2010 to 2016. Patients were identified by a retrospective database search. Data were collected from medical files. The presence of vomiting was associated with background and headache-related parameters...
May 7, 2017: Headache
https://www.readbyqxmd.com/read/28461833/treatment-of-pediatric-migraine-a-review
#20
Teleanu Raluca Ioana, Vladacenco Oana, Teleanu Daniel Mihai, Epure Diana Anamaria
Migraine is a common, but often underdiagnosed complaint in children and the lack of studies regarding its treatment in this particularly population makes it harder to enlarge the choices of treatment. However, recent trials made it easier to utilize newer compounds that improve the outcome of the disease. We reviewed the treatment of pediatric migraine and divided therapeutic methods into two broad areas: treatment of the acute attack - used both in the emergency room and as home options and prophylactic agents...
June 2016: Mædica
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