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https://www.readbyqxmd.com/read/27903495/testosterone-treatment-and-risk-of-venous-thromboembolism-population-based-case-control-study
#1
Carlos Martinez, Samy Suissa, Stephan Rietbrock, Anja Katholing, Ben Freedman, Alexander T Cohen, David J Handelsman
OBJECTIVE:  To determine the risk of venous thromboembolism associated with use of testosterone treatment in men, focusing particularly on the timing of the risk. DESIGN:  Population based case-control study SETTING:  370 general practices in UK primary care with linked hospital discharge diagnoses and in-hospital procedures and information on all cause mortality. PARTICIPANTS:  19 215 patients with confirmed venous thromboembolism (comprising deep venous thrombosis and pulmonary embolism) and 909 530 age matched controls from source population including more than 2...
November 30, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27891115/methanotrophy-under-versatile-conditions-in-the-water-column-of-the-ferruginous-meromictic-lake-la-cruz-spain
#2
Kirsten Oswald, Corinne Jegge, Jana Tischer, Jasmine Berg, Andreas Brand, María R Miracle, Xavier Soria, Eduardo Vicente, Moritz F Lehmann, Jakob Zopfi, Carsten J Schubert
Lakes represent a considerable natural source of methane to the atmosphere compared to their small global surface area. Methanotrophs in sediments and in the water column largely control methane fluxes from these systems, yet the diversity, electron accepting capacity, and nutrient requirements of these microorganisms have only been partially identified. Here, we investigated the role of electron acceptors alternative to oxygen and sulfate in microbial methane oxidation at the oxycline and in anoxic waters of the ferruginous meromictic Lake La Cruz, Spain...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27875180/surprise-bayesian-weighting-for-de-biasing-thematic-maps
#3
Michael Correll, Jeffrey Heer
Thematic maps are commonly used for visualizing the density of events in spatial data. However, these maps can mislead by giving visual prominence to known base rates (such as population densities) or to artifacts of sample size and normalization (such as outliers arising from smaller, and thus more variable, samples). In this work, we adapt Bayesian surprise to generate maps that counter these biases. Bayesian surprise, which has shown promise for modeling human visual attention, weights information with respect to how it updates beliefs over a space of models...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27871854/rate-adaptive-pacing-in-an-intracardiac-pacemaker
#4
Michael Lloyd, Dwight Reynolds, Todd Sheldon, Kurt Stromberg, J Harrison Hudnall, Wade M Demmer, Razali Omar, Philippe Ritter, John Hummel, Lluís Mont, Clemens Steinwender, Gabor Z Duray
BACKGROUND: The Micra transcatheter pacemaker was designed to have similar functionality to conventional transvenous VVIR pacing systems. It provides rate adaptive pacing using a programmable 3-axis accelerometer designed to detect patient activity in the presence of cardiac motion. OBJECTIVE: We evaluated the system's performance during treadmill tests to maximum exertion in a subset of patients within the Micra TPS Global Clinical Trial. METHODS: Patients underwent treadmill testing at 3 or 6-months post-implant with algorithm programming at physician discretion...
November 15, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/27859952/strong-thermal-acclimation-of-photosynthesis-in-tropical-and-temperate-wet-forest-tree-species-the-importance-of-altered-rubisco-content
#5
Andrew P Scafaro, Shuang Xiang, Benedict M Long, Nur H A Bahar, Lasantha K Weerasinghe, Danielle Creek, John R Evans, Peter B Reich, Owen K Atkin
Understanding of the extent of acclimation of light-saturated net photosynthesis (An ) to temperature (T), and associated underlying mechanisms, remains limited. This is a key knowledge gap given the importance of thermal acclimation for plant functioning, both under current and future higher temperatures, limiting the accuracy and realism of Earth System Model (ESM) predictions. Given this, we analysed and modelled T-dependent changes in photosynthetic capacity in 10 wet-forest tree species; six from temperate forests and four from tropical forests...
November 16, 2016: Global Change Biology
https://www.readbyqxmd.com/read/27852333/emergency-department-visits-for-attempted-suicide-and-self-harm-in-the-usa-2006-2013
#6
J K Canner, K Giuliano, S Selvarajah, E R Hammond, E B Schneider
AIMS: To characterise and identify nationwide trends in suicide-related emergency department (ED) visits in the USA from 2006 to 2013. METHODS: We used data from the Nationwide Emergency Department Sample (NEDS) from 2006 to 2013. E-codes were used to identify ED visits related to suicide attempts and self-inflicted injury. Visits were characterised by factors such as age, sex, US census region, calendar month, as well as injury severity and mechanism. Injury severity and mechanism were compared between age groups and sex by chi-square tests and Wilcoxon rank-sum tests...
November 17, 2016: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/27847148/sulfamethazine-degradation-in-water-by-the-vuv-uv-process-kinetics-mechanism-and-antibacterial-activity-determination-based-on-a-mini-fluidic-vuv-uv-photoreaction-system
#7
Mengkai Li, Chen Wang, Miaoling Yau, James R Bolton, Zhimin Qiang
A mini-fluidic VUV/UV photoreaction system (MVPS) was developed in our previous study, and it was demonstrated as a powerful tool for studies on pollutant degradation by the VUV/UV process. In this study, we investigated the VUV/UV photodegradation of sulfamethazine (SMN), one of the most frequently detected antibiotics in the environment. The determination methods of photochemical kinetic parameters (e.g., photon fluence-based rate constant and quantum yield) were developed based on the MVPS. The photon fluence-based reaction rate constants for SMN degradation by UV alone and VUV/UV processes were determined as 0...
November 4, 2016: Water Research
https://www.readbyqxmd.com/read/27827539/exploratory-analysis-of-cvlt-ii-forced-choice-recognition-and-rbans-ei-base-rates-for-forensically-committed-psychotic-disordered-inpatients-implications-on-clinical-decision-making
#8
Stacey M Bayan, Steve Nitch, Dominique Kinney, Marina Kaminetskaya
Within the inpatient forensic setting, requests for a neuropsychological evaluation are common to determine cognitive strengths and weaknesses. However, variable effort proves to be a prominent issue in this setting. Thus, assessment of effort becomes an essential component of a neuropsychological evaluation. The California Verbal Learning Test, 2nd Edition (CVLT-II) and the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) are widely utilized cognitive measures in the inpatient setting...
November 9, 2016: Applied Neuropsychology. Adult
https://www.readbyqxmd.com/read/27815818/effects-of-outcome-and-trial-frequency-on-the-inverse-base-rate-effect
#9
Hilary J Don, Evan J Livesey
The inverse base-rate effect is a bias in contingency learning in which participants tend to predict a rare outcome for a conflicting set of perfectly predictive cues. Although the effect is often explained by attention biases during learning, inferential strategies at test may also contribute substantially to the effect. In three experiments, we manipulated the frequencies of outcomes and trial types to determine the critical conditions for the effect, thereby providing novel tests of the reasoning processes that could contribute to it...
November 4, 2016: Memory & Cognition
https://www.readbyqxmd.com/read/27777274/involuntary-outpatient-commitment-and-the-elusive-pursuit-of-violence-prevention-a-view-from-the-united-states
#10
Marvin S Swartz, Sayanti Bhattacharya, Allison G Robertson, Jeffrey W Swanson
OBJECTIVE: Involuntary outpatient commitment (OPC)-also referred to as 'assisted outpatient treatment' or 'community treatment orders'-are civil court orders whereby persons with serious mental illness and repeated hospitalisations are ordered to adhere to community-based treatment. Increasingly, in the United States, OPC is promoted to policy makers as a means to prevent violence committed by persons with mental illness. This article reviews the background and context for promotion of OPC for violence prevention and the empirical evidence for the use of OPC for this goal...
October 24, 2016: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/27770067/objective-computerized-video-based-rating-of-blepharospasm-severity
#11
David A Peterson, Gwen C Littlewort, Marian S Bartlett, Antonella Macerollo, Joel S Perlmutter, H A Jinnah, Mark Hallett, Terrence J Sejnowski
OBJECTIVE: To compare clinical rating scales of blepharospasm severity with involuntary eye closures measured automatically from patient videos with contemporary facial expression software. METHODS: We evaluated video recordings of a standardized clinical examination from 50 patients with blepharospasm in the Dystonia Coalition's Natural History and Biorepository study. Eye closures were measured on a frame-by-frame basis with software known as the Computer Expression Recognition Toolbox (CERT)...
November 15, 2016: Neurology
https://www.readbyqxmd.com/read/27767344/the-development-of-the-inventory-of-problems-29-a-brief-self-administered-measure-for-discriminating-bona-fide-from-feigned-psychiatric-and-cognitive-complaints
#12
Donald J Viglione, Luciano Giromini, Patricia Landis
This article describes the development of the Inventory of Problems-29 (IOP-29), a new, short, paper-and-pencil, self-administered measure of feigned mental and cognitive disorders. Four clinical comparison simulation studies were conducted. Study 1 (n = 451) selected the items and produced an index of potential feigning. Study 2 (n = 331) scaled this index to produce a probability score, and examined its psychometric properties. Study 3 tested the generalizability of Study 2's findings with 2 additional samples (ns = 128 and 90)...
October 21, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27760236/disease-burden-and-symptom-structure-of-autism-in-neurofibromatosis-type-1-a-study-of-the-international-nf1-asd-consortium-team-infact
#13
Stephanie M Morris, Maria T Acosta, Shruti Garg, Jonathan Green, Susan Huson, Eric Legius, Kathryn N North, Jonathan M Payne, Ellen Plasschaert, Thomas W Frazier, Lauren A Weiss, Yi Zhang, David H Gutmann, John N Constantino
Importance: Recent reports have demonstrated a higher incidence of autism spectrum disorder (ASD) and substantially elevated autistic trait burden in individuals with neurofibromatosis type 1 (NF1). However, important discrepancies regarding the distribution of autistic traits, sex predominance, and association between ASD symptoms and attentional problems have emerged, and critical features of the ASD phenotype within NF1 have never been adequately explored. Establishing NF1 as a monogenic cause for ASD has important implications for affected patients and for future research focused on establishing convergent pathogenic mechanisms relevant to the potential treatment targets for ASD...
October 19, 2016: JAMA Psychiatry
https://www.readbyqxmd.com/read/27752962/physician-bayesian-updating-from-personal-beliefs-about-the-base-rate-and-likelihood-ratio
#14
Benjamin Margolin Rottman
Whether humans can accurately make decisions in line with Bayes' rule has been one of the most important yet contentious topics in cognitive psychology. Though a number of paradigms have been used for studying Bayesian updating, rarely have subjects been allowed to use their own preexisting beliefs about the prior and the likelihood. A study is reported in which physicians judged the posttest probability of a diagnosis for a patient vignette after receiving a test result, and the physicians' posttest judgments were compared to the normative posttest calculated from their own beliefs in the sensitivity and false positive rate of the test (likelihood ratio) and prior probability of the diagnosis...
October 17, 2016: Memory & Cognition
https://www.readbyqxmd.com/read/27750183/risky-driving-and-sexual-behaviors-as-developmental-outcomes-of-co-occurring-substance-use-and-antisocial-behavior
#15
Jeremy W Luk, Matthew J Worley, Evan Winiger, Ryan S Trim, Christian J Hopfer, John K Hewitt, Sandra A Brown, Tamara L Wall
PURPOSE: To examine the associations between substance use and antisocial behavior trajectories and seven risky behaviors over time. METHOD: Data were collected from a high-risk sample of adolescents followed into young adulthood. Five trajectory classes, identified based on dual development of substance use and antisocial behavior symptoms, were used to predict three risky driving and four risky sexual behaviors. RESULTS: In this high-risk sample (n=530), participants reported notably high overall rates of reckless driving (55...
October 11, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27743321/factor-analysis-of-the-childhood-autism-rating-scale-in-a-sample-of-two-year-olds-with-an-autism-spectrum-disorder
#16
Emily Moulton, Kathryn Bradbury, Marianne Barton, Deborah Fein
The Childhood Autism Rating Scale (CARS), (Schopler et al. in J Autism Dev Disord 10(1):91-103, 1980) is a 15-item observation-based rating scale that yields a total score reflective of autism symptom severity. This study investigated the factor structure of the CARS in a sample of 2-year-old children with DSM-IV-TR (American Psychiatric Association in Diagnostic and statistical manual of mental disorders, 4th edn. American Psychiatric Publishing, Washington, 2000) diagnoses of AD or PDD-NOS. Following a preliminary internal cross-validation, principal axis factor analysis was completed (N = 282)...
October 14, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27728998/transforming-core-emotional-pain-in-a-course-of-emotion-focused-therapy-for-depression-a-case-study
#17
Andrew Dillon, Ladislav Timulak, Leslie S Greenberg
OBJECTIVE: To investigate the pattern of change in emotional states over a course of emotion-focused therapy using the model of sequential emotional processing as an initial framework for analysis. METHOD: This was a single case study observational design examining 15 sessions of therapy with one client. A qualitative analysis of moment-to-moment shifts in client emotional events was conducted. This conceptualised the interplay between experienced emotions using the sequential emotional processing model as an interpretative framework...
October 11, 2016: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/27724157/neuropsychological-functioning-in-preschool-aged-children-undergoing-evaluation-for-organ-transplant
#18
Tanya N Antonini, Stacey S Beer, Tamir Miloh, William J Dreyer, Susan E Caudle
OBJECTIVE: The purpose of this study was to review the current literature on neuropsychological functioning in two groups of children requiring organ transplants (liver or heart) and present recent clinical data collected through the liver and cardiac transplantation programs at a large pediatric academic medical center. METHOD: Data included in this study came from 18 patients who completed evaluations for heart transplant (n = 8) or liver transplant (n = 10) between the ages of 2 and 6 years (inclusive)...
October 11, 2016: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/27723238/incidence-of-pulmonary-embolism-in-patients-with-newly-diagnosed-colorectal-cancer
#19
Eric S Daniel, Anastasia E Dean, Mingjoe Lim, Mobin Master, Peter Gibbs, Ian Faragher
BACKGROUND: Studies have suggested a benefit from extended venous thromboprophylaxis post-operatively in colorectal cancer with an assumed base rate of zero venous thromboembolic events prior to treatment. We aim to establish the incidence of pulmonary embolism in patients with newly diagnosed stage III or IV colorectal cancer prior to any treatment. METHOD: Consecutive patients presenting to a single health service with a new diagnosis of stage III or IV colorectal cancer were identified from a prospective database, for the period between January 2011 and September 2014...
October 9, 2016: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/27713710/cognitive-reflection-decision-biases-and-response-times
#20
Carlos Alós-Ferrer, Michele Garagnani, Sabine Hügelschäfer
We present novel evidence on response times and personality traits in standard questions from the decision-making literature where responses are relatively slow (medians around half a minute or above). To this end, we measured response times in a number of incentivized, framed items (decisions from description) including the Cognitive Reflection Test, two additional questions following the same logic, and a number of classic questions used to study decision biases in probability judgments (base-rate neglect, the conjunction fallacy, and the ratio bias)...
2016: Frontiers in Psychology
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