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https://www.readbyqxmd.com/read/28635208/association-of-clinical-characteristics-of-patients-presenting-with-influenza-like-illness-or-severe-acute-respiratory-illness-with-development-of-acute-respiratory-distress-syndrome
#1
Muhammad Ijaz, Muhammad Jaffar Khan, Jawad Khan, Usama Usama
Clinical judgement and suspicion of influenza based on signs and symptoms of influenza-like illness and severe acute respiratory illness are critical for better patient outcome. Whether clinical characteristics of patients are associated with the development of acute respiratory distress syndrome and PCR positivity of samples was the aim of this study. We included all patients (n=37) presenting with influenza like illness (ILI) or severe acute respiratory illness (SARI) to a tertiary care hospital in northwest Pakistan during December 2015 until the end of January 2016...
May 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28573405/diagnostic-accuracy-of-clinical-dehydration-scales-in-children
#2
Anna Falszewska, Piotr Dziechciarz, Hania Szajewska
The aim of this study was to evaluate the diagnostic accuracy of the Clinical Dehydration Scale (CDS), the World Health Organization (WHO) scale, and the Gorelick scale for dehydration assessment in children. A prospective, observational study was carried out between October 2014 and December 2016. Eligible participants were children aged 1 month to 5 years with acute diarrhea. After hospital admission, each patient's weight was recorded and the degree of dehydration based on three scales was assessed. The reference standard was the percentage weight change between the discharge and admission weights...
August 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28515805/is-computed-tomography-defined-obstruction-a-predictor-of-urological-intervention-in-emergency-department-patients-presenting-with-renal-colic
#3
Peter Alexander Massaro, Avinash Kanji, Paul Atkinson, Ryan Pawsey, Tom Whelan
INTRODUCTION: Our objective was to determine whether unilateral calculus-induced ureteric obstruction on computed tomography (CT) was independently associated with the need for urological intervention and 30-day return to the emergency department (ED). METHODS: We performed a retrospective cohort study of patients with symptomatic urinary calculi diagnosed by unenhanced helical CT. Stepwise regression analysis was used to determine the predictors of urological intervention and 30-day return to the ED...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28498290/the-relationship-between-mri-signal-intensity-changes-clinical-presentation-and-surgical-outcome-in-degenerative-cervical-myelopathy-analysis-of-a-global-cohort
#4
Aria Nouri, Allan R Martin, So Kato, Hamed Reihani-Kermani, Lauren E Riehm, Michael G Fehlings
STUDY DESIGN: Retrospective analysis of prospective data OBJECTIVE.: To assess the relationship between MRI signal intensity changes, clinical presentation, and surgical outcome in degenerative cervical myelopathy (DCM). SUMMARY OF BACKGROUND DATA: Several studies have sought to assess the extent of spinal cord dysfunction and the potential for postoperative neurological recovery through the evaluation of spinal cord signal change on T2-weighted (T2WI) and T1-weighted images (T1WI)...
May 11, 2017: Spine
https://www.readbyqxmd.com/read/28492211/raised-adenosine-deaminase-in-the-cerebrospinal-fluid-a-tool-for-the-diagnosis-of-tuberculous-meningitis-in-developing-countries
#5
Purti A Saini, Preeti R Chakrabarti, Dosi Shilpi, Gambhir Shankhini, Gupta Priyanka, Tignath Gargi
CONTEXT: The rapid diagnosis followed by the early treatment of tuberculous meningitis (TBM) is important in preventing fatal outcomes. The mainstay of diagnosis lies in cerebrospinal fluid (CSF) analysis, radiological investigations, and clinical findings. AIM: The present study was conducted to determine the efficacy, sensitivity, and specificity of raised adenosine deaminase (ADA) level in CSF to differentiate TBM from non-TBM cases as a rapid, cost-effective, and noninvasive test...
January 2017: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28484063/clinical-diagnosis-of-bordetella-pertussis-infection-a-systematic-review
#6
Mark H Ebell, Christian Marchello, Maria Callahan
BACKGROUND: Bordetella pertussis (BP) is a common cause of prolonged cough. Our objective was to perform an updated systematic review of the clinical diagnosis of BP without restriction by patient age. METHODS: We identified prospective cohort studies of patients with cough or suspected pertussis and assessed study quality using QUADAS-2. We performed bivariate meta-analysis to calculate summary estimates of accuracy and created summary receiver operating characteristic curves to explore heterogeneity by vaccination status and age...
May 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28369696/use-of-medications-of-questionable-benefit-at-the-end-of-life-in-nursing-home-residents-with-advanced-dementia
#7
Jeremy N Matlow, Susan E Bronskill, Andrea Gruneir, Chaim M Bell, Nathan M Stall, Nathan Herrmann, Dallas P Seitz, Sudeep S Gill, Peter C Austin, Hadas D Fischer, Kinwah Fung, Wei Wu, Paula A Rochon
OBJECTIVES: To determine the prevalence of and resident characteristics associated with the prescription of medications of questionable benefit (MQBs) near the end of life in older adults with advanced dementia in nursing homes. DESIGN: Population-based, cross-sectional study using Resident Assessment Instrument Minimum Data Set 2.0 linked to health administrative data. SETTING: Ontario, Canada. PARTICIPANTS: All 9,298 nursing home residents with advanced dementia who died between June 1, 2010, and March 31, 2013; were aged 66 and older at time of death; and received at least one MQB in their last year of life...
March 29, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28237520/smoking-as-a-risk-factor-for-breast-reduction-an-analysis-of-13-503-cases
#8
Jeffery S Hillam, Emily A Borsting, Jimmy H Chim, Seth R Thaller
BACKGROUND: Reduction mammaplasty is one of the most common reconstructive procedures performed by plastic surgeons. Over 100,000 procedures are performed annually. Although important for relieving the painful symptoms associated with macromastia, complication rates of this procedure are not insignificant. They are reported in up to half the cases. Reported risk factors for adverse outcomes include obesity, preoperative wound infection, and advanced American Society of Anesthesiologists status...
June 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28220474/buprenorphine-for-managing-opioid-withdrawal
#9
REVIEW
Linda Gowing, Robert Ali, Jason M White, Dalitso Mbewe
BACKGROUND: Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of substitution treatment. OBJECTIVES: To assess the effects of buprenorphine versus tapered doses of methadone, alpha2-adrenergic agonists, symptomatic medications or placebo, or different buprenorphine regimens for managing opioid withdrawal, in terms of the intensity of the withdrawal syndrome experienced, duration and completion of treatment, and adverse effects...
February 21, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28167685/external-validation-of-the-fullpiers-model-for-predicting-adverse-maternal-outcomes-in-pregnancy-hypertension-in-low-and-middle-income-countries
#10
U Vivian Ukah, Beth Payne, Tang Lee, Laura A Magee, Peter von Dadelszen
The hypertensive disorders of pregnancy are leading causes of maternal mortality and morbidity, especially in low- and middle-income countries. Early identification of women with preeclampsia and other hypertensive disorders of pregnancy at high risk of complications will aid in reducing this health burden. The fullPIERS model (Preeclampsia Integrated Estimate of Risk) was developed for predicting adverse maternal outcomes from preeclampsia using data from tertiary centers in high-income countries and uses maternal demographics, signs, symptoms, and laboratory tests as predictors...
April 2017: Hypertension
https://www.readbyqxmd.com/read/28056149/hearing-impairment-and-undiagnosed-disease-the-potential-role-of-clinical-recommendations
#11
Nicole M Marlow, John Malaty, Ara Jo, Rebecca J Tanner, Valery M Beau de Rochars, Peter J Carek, Arch G Mainous
Purpose: The objective of this study was to use cross-sectional, nationally representative data to examine the relationship between self-reported hearing impairment and undetected diabetes, hypertension, hypercholesterolemia, and chronic kidney disease. Method: We analyzed the National Health and Nutrition Examination Survey for the years 2007-2012 for individuals 40 years of age and older without previously diagnosed cardiovascular disease. Analyses were conducted examining hearing impairment and undiagnosed disease...
January 1, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28043530/rapid-detection-of-mycobacterium-tuberculosis-complex-in-sputum-samples-using-pure-tb-lamp-assay
#12
K N'guessan, K Horo, I Coulibaly, J Adegbele, N Kouame-Adjei, H Seck-Angu, A Guei, J Kouakou, M Dosso
OBJECTIVE/BACKGROUND: Lack of rapid and accurate diagnostic testing is a critical obstacle to global tuberculosis (TB) control. Sensitivity of sputum smear microscopy (SSM) is not optimal; however, it remains the most prevalent tool for TB confirmation in poor countries. As a part of passive case finding of TB detection, this study was conducted to determine the clinical performance of PURE TB-LAMP assay using liquid culture medium as the gold standard. METHODS: Centre Antituberculeux de Yopougon is one of the 17 intermediate Tuberculosis centers in Côte d'Ivoire...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27982310/correlation-between-classification-in-risk-categories-and-clinical-aspects-and-outcomes
#13
Gabriella Novelli Oliveira, Cássia Regina Vancini-Campanharo, Maria Carolina Barbosa Teixeira Lopes, Dulce Aparecida Barbosa, Meiry Fernanda Pinto Okuno, Ruth Ester Assayag Batista
Objective: to correlate classification in risk categories with the clinical profiles, outcomes and origins of patients. Method: analytical cross-sectional study conducted with 697 medical forms of adult patients. The variables included: age, sex, origin, signs and symptoms, exams, personal antecedents, classification in risk categories, medical specialties, and outcome. The Chi-square and likelihood ratio tests were used to associate classifications in risk categories with origin, signs and symptoms, exams, personal antecedents, medical specialty, and outcome...
December 8, 2016: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/27938961/clinical-predictors-of-positive-temporal-artery-biopsy
#14
Andrew Toren, Ezekiel Weis, Vivek Patel, Bethany Monteith, Steven Gilberg, David Jordan
OBJECTIVE: We investigated the ability of known clinical signs and symptoms, as well as common laboratory tests, to correctly predict a positive temporal artery biopsy. DESIGN: A prospective cohort study. PARTICIPANTS: Consecutive patients in a tertiary referral centre undergoing temporal artery biopsy. METHODS: Clinical information was collected using a predesigned questionnaire. Pathology results and laboratory information were collected from digital patient records...
December 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/27764177/development-validation-and-field-testing-of-an-instrument-for-clinical-assessment-of-hiv-associated-neuropathy-and-neuropathic-pain-in-resource-restricted-and-large-population-study-settings
#15
Yohannes W Woldeamanuel, Peter R Kamerman, Demetri G A Veliotes, Tudor J Phillips, David Asboe, Marta Boffito, Andrew S C Rice
HIV-associated sensory peripheral neuropathy (HIV-SN) afflicts approximately 50% of patients on antiretroviral therapy, and is associated with significant neuropathic pain. Simple accurate diagnostic instruments are required for clinical research and daily practice in both high- and low-resource setting. A 4-item clinical tool (CHANT: Clinical HIV-associated Neuropathy Tool) assessing symptoms (pain and numbness) and signs (ankle reflexes and vibration sense) was developed by selecting and combining the most accurate measurands from a deep phenotyping study of HIV positive people (Pain In Neuropathy Study-HIV-PINS)...
2016: PloS One
https://www.readbyqxmd.com/read/27695337/clinical-prediction-rules-for-failed-nonoperative-reduction-of-intussusception
#16
Jiraporn Khorana, Jayanton Patumanond, Nuthapong Ukarapol, Mongkol Laohapensang, Pannee Visrutaratna, Jesda Singhavejsakul
PURPOSE: The nonoperative reduction of intussusception in children can be performed safely if there are no contraindications. Many risk factors associated with failed reduction were defined. The aim of this study was to develop a scoring system for predicting the failure of nonoperative reduction using various determinants. PATIENTS AND METHODS: The data were collected from Chiang Mai University Hospital and Siriraj Hospital from January 2006 to December 2012. Inclusion criteria consisted of patients with intussusception aged 0-15 years with no contraindications for nonoperative reduction...
2016: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/27406968/prospective-validation-of-the-niaid-faan-criteria%C3%A2-for-emergency-department-diagnosis-of-anaphylaxis
#17
Caitlin E Loprinzi Brauer, Megan S Motosue, James T Li, John B Hagan, M Fernanda Bellolio, Sangil Lee, Ronna L Campbell
BACKGROUND: Anaphylaxis diagnostic criteria were proposed at the Second Symposium on the Definition and Management of Anaphylaxis. These criteria were 97% sensitive and 82% specific when retrospectively validated. OBJECTIVE: To prospectively evaluate the diagnostic accuracy of the National Institute of Allergy and Infectious Diseases/Food Allergy and Anaphylaxis Network (NIAID/FAAN) criteria for diagnosis of anaphylaxis in the emergency department (ED). METHODS: We conducted a prospective observational study of patients seen in our institution's ED from April 2010 to March 2013...
July 9, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27325129/predicting-low-testosterone-in-aging-men-a-systematic-review
#18
REVIEW
Adam C Millar, Adrian N C Lau, George Tomlinson, Alan Kraguljac, David L Simel, Allan S Detsky, Lorraine L Lipscombe
BACKGROUND: Physicians diagnose and treat suspected hypogonadism in older men by extrapolating from the defined clinical entity of hypogonadism found in younger men. We conducted a systematic review to estimate the accuracy of clinical symptoms and signs for predicting low testosterone among aging men. METHODS: We searched the MEDLINE and Embase databases (January 1966 to July 2014) for studies that compared clinical features with a measurement of serum testosterone in men...
September 20, 2016: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/27306497/spontaneous-subarachnoid-hemorrhage-a-systematic-review-and-meta-analysis-describing-the-diagnostic-accuracy-of-history-physical-examination-imaging-and-lumbar-puncture-with-an-exploration-of-test-thresholds
#19
Christopher R Carpenter, Adnan M Hussain, Michael J Ward, Gregory J Zipfel, Susan Fowler, Jesse M Pines, Marco L A Sivilotti
BACKGROUND: Spontaneous subarachnoid hemorrhage (SAH) is a rare, but serious etiology of headache. The diagnosis of SAH is especially challenging in alert, neurologically intact patients, as missed or delayed diagnosis can be catastrophic. OBJECTIVES: The objective was to perform a diagnostic accuracy systematic review and meta-analysis of history, physical examination, cerebrospinal fluid (CSF) tests, computed tomography (CT), and clinical decision rules for spontaneous SAH...
September 2016: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/27140827/alpha%C3%A2-adrenergic-agonists-for-the-management-of-opioid-withdrawal
#20
REVIEW
Linda Gowing, Michael Farrell, Robert Ali, Jason M White
BACKGROUND: Withdrawal is a necessary step prior to drug-free treatment or as the endpoint of long-term substitution treatment. OBJECTIVES: To assess the effectiveness of interventions involving the use of alpha2-adrenergic agonists compared with placebo, reducing doses of methadone, symptomatic medications, or an alpha2-adrenergic agonist regimen different to the experimental intervention, for the management of the acute phase of opioid withdrawal. Outcomes included the withdrawal syndrome experienced, duration of treatment, occurrence of adverse effects, and completion of treatment...
May 3, 2016: Cochrane Database of Systematic Reviews
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