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https://www.readbyqxmd.com/read/28544356/older-people-s-experiences-of-falling-and-perceived-risk-of-falls-in-the-community-a-narrative-synthesis-of-qualitative-research
#1
REVIEW
Siobhan Gardiner, Margaret Glogowska, Catherine Stoddart, Sarah Pendlebury, Daniel Lasserson, Debra Jackson
AIM: To examine qualitative research exploring older people's experiences of falling and the perceived risk of falling in the community. This will contribute new insights into how falling is perceived by the older community. BACKGROUND: Falls are a major problem for older people and healthcare services across the world. Accidental falls in the community are a persistent problem that is generally recognised as an intrinsic risk of ageing. This review provides a new synthesis of evidence that considers older people's perception of falls in the community as new insights are needed if the increasing problems of falls are to be addressed...
May 22, 2017: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/28540744/production-of-single-cell-protein-scp-from-food-and-agricultural-waste-by-using-saccharomyces-cerevisiae
#2
Teresa Gervasi, Vito Pellizzeri, Giorgio Calabrese, Giuseppa Di Bella, Nicola Cicero, Giacomo Dugo
Food waste is the single-largest component of the waste stream, in order to protect and safeguard the public health, useful and innovative recycling methods are investigated. The conversion of food wastes in value-added products is becoming a more economically viable and interesting practice. Food waste, collected in the distribution sector and citrus industries, was characterised for its potential as a raw material to use in fermentation processes. In this study, the production of single-cell protein (SCP) using food waste as a substrate was investigated...
May 25, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28540561/and-the-band-played-on-before-and-after
#3
William W Darrow
In fall 1987, Randy Shilts published his second book, "And the Band Played on: Politics, People, and the AIDS Epidemic." The jacket proclaimed that "the epidemic spread widely because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were more often more concerned with international prestige than saving lives." In the Prologue Shilts wrote, "The bitter truth was that AIDS did not just happen to America-it was allowed to happen by an array of institutions, all of which failed to perform their appropriate tasks to safeguard the public health...
May 24, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28539931/characterization-and-phylogenetic-analysis-of-ancient-italian-landraces-of-pear
#4
Nicoletta Ferradini, Hovirag Lancioni, Renzo Torricelli, Luigi Russi, Isabella Dalla Ragione, Irene Cardinali, Gianpiero Marconi, Mauro Gramaccia, Luciano Concezzi, Alessandro Achilli, Fabio Veronesi, Emidio Albertini
Pear is one of the oldest fruit tree crops and the third most important temperate fruit species. Its domestication took place independently in the Far East (China) and in the Caucasus region. While the origin of Eastern Asian cultivars is clear, that of European cultivars is still in doubt. Italy has a wealth of local varieties and genetic resources safeguarded by several public and private collections to face the erosion caused by the introduction of improved varieties in specialized orchards. The objectives of the present study were: (i) to characterize the existing germplasm through nuclear (SSR) and (ii) to clarify the genetic divergence between local and cultivated populations through chloroplast DNA (cpDNA) markers in order to provide insights into phylogenetic relationships of Pyrus spp...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28538001/translation-and-cultural-adaptation-of-the-scored-patient-generated-subjective-global-assessment-an-interdisciplinary-nutritional-instrument-appropriate-for-dutch-cancer-patients
#5
Martine J Sealy, Ulrike Haß, Faith D Ottery, Cees P van der Schans, Jan L N Roodenburg, Harriët Jager-Wittenaar
BACKGROUND: Assessment of malnutrition is important in cancer patients. The Scored Patient-Generated Subjective Global Assessment (PG-SGA), an instrument that enables interdisciplinary assessment of malnutrition and its risk factors, was not available in Dutch. OBJECTIVE: Translation and cultural adaption of the original English PG-SGA to the Dutch setting. METHODS: The PG-SGA was translated and culturally adapted, following the International Society for Pharmacoeconomics and Outcomes Research principles...
May 19, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28536092/a-personalized-and-interactive-web-based-health-care-innovation-to-advance-the-quality-of-life-and-care-of-patients-with-heart-failure-acquire-hf-a-mixed-methods-feasibility-study
#6
Susanne S Pedersen, Thomas Schmidt, Søren Jensen Skovbakke, Uffe Kock Wiil, Kenneth Egstrup, Kim G Smolderen, John A Spertus
BACKGROUND: Heart failure (HF) is a progressive, debilitating, and complex disease, and due to an increasing incidence and prevalence, it represents a global health and economic problem. Hence, there is an urgent need to evaluate alternative care modalities to current practice to safeguard a high level of care for this growing population. OBJECTIVE: Our goal was to examine the feasibility of engaging patients to use patient-centered and personalized tools coupled with a Web-based, shared care and interactive platform in order to empower and enable them to live a better life with their disease...
May 23, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28534616/microbes-and-the-next-nitrogen-revolution
#7
Ilje Pikaar, Silvio Matassa, Korneel Rabaey, Benjamin Leon Bodirsky, Alexander Popp, Mario Herrero, Willy Verstraete
The Haber Bosch process is among the greatest inventions of the 20th century. It provided agriculture with reactive nitrogen and ultimately mankind with nourishment for a population of 7 billion people. However, the present agricultural practice of growing crops for animal production and human food constitutes a major threat to the sustainability of the planet in terms of reactive nitrogen pollution. In view of the shortage of directly feasible and cost-effective measures to avoid these planetary nitrogen burdens and the necessity to remediate this problem, we foresee the absolute need for, and expect, a revolution in the use of microbes as a source of protein...
May 23, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28533972/characterisation-of-false-positive-observations-in-botanical-surveys
#8
Quentin J Groom, Sarah J Whild
Errors in botanical surveying are a common problem. The presence of a species is easily overlooked, leading to false-absences; while misidentifications and other mistakes lead to false-positive observations. While it is common knowledge that these errors occur, there are few data that can be used to quantify and describe these errors. Here we characterise false-positive errors for a controlled set of surveys conducted as part of a field identification test of botanical skill. Surveys were conducted at sites with a verified list of vascular plant species...
2017: PeerJ
https://www.readbyqxmd.com/read/28533900/control-of-gene-expression-through-the-nonsense-mediated-rna-decay-pathway
#9
REVIEW
Andrew Nickless, Julie M Bailis, Zhongsheng You
Nonsense-mediated RNA decay (NMD) was originally discovered as a cellular surveillance pathway that safeguards the quality of mRNA transcripts in eukaryotic cells. In its canonical function, NMD prevents translation of mutant mRNAs harboring premature termination codons (PTCs) by targeting them for degradation. However, recent studies have shown that NMD has a much broader role in gene expression by regulating the stability of many normal transcripts. In this review, we discuss the function of NMD in normal physiological processes, its dynamic regulation by developmental and environmental cues, and its association with human disease...
2017: Cell & Bioscience
https://www.readbyqxmd.com/read/28533561/national-ecosystem-assessments-in-europe-a-review
#10
Matthias Schröter, Christian Albert, Alexandra Marques, Wolke Tobon, Sandra Lavorel, Joachim Maes, Claire Brown, Stefan Klotz, Aletta Bonn
National ecosystem assessments form an essential knowledge base for safeguarding biodiversity and ecosystem services. We analyze eight European (sub-)national ecosystem assessments (Portugal, United Kingdom, Spain, Norway, Flanders, Netherlands, Finland, and Germany) and compare their objectives, political context, methods, and operationalization. We observed remarkable differences in breadth of the assessment, methods employed, variety of services considered, policy mandates, and funding mechanisms. Biodiversity and ecosystem services are mainly assessed independently, with biodiversity conceptualized as underpinning services, as a source of conflict with services, or as a service in itself...
October 1, 2016: Bioscience
https://www.readbyqxmd.com/read/28533526/are-we-getting-closer-to-using-intellectual-property-safeguards-to-improve-public-health-ellen-t-hoen-private-patents-and-public-health-changing-intellectual-property-rules-for-access-to-medicines-amb-diemen-the-netherlands-20i6-181-pp-%C3%A2-45-00-paper-isbn-97890
#11
https://www.readbyqxmd.com/read/28533419/dna-replication-and-mismatch-repair-safeguard-against-metabolic-imbalances
#12
Carol M Manhart, Eric Alani
No abstract text is available yet for this article.
May 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28526855/gut-homeostasis-and-regulatory-t-cell-induction-depend-on-molecular-chaperone-gp96-in-cd11c-cells
#13
Yunpeng Hua, Yi Yang, Shaoli Sun, Stephen Iwanowycz, Caroline Westwater, Boris Reizis, Zihai Li, Bei Liu
The intestinal immunity and tolerance are orchestrated by both the innate and the adaptive immune system. Intestinal professional antigen presenting cells (pAPCs) recognize and respond to the gut microbiota through multiple pattern-recognition receptors, including TLRs and NLRs. How gut pAPCs maintain mucosal homeostasis remains incompletely understood. Heat shock protein gp96, also known as grp94, is an essential immune chaperone for TLRs. However, the role of gp96 in regulating CD11c(+) APCs in the gut immunity and tolerance is unknown...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28525771/return-of-the-ice-age-caspases-safeguard-against-inflammatory-cell-death
#14
Marcin Poreba, Guy Salvesen
In a recent issue of Cell Chemical Biology, Taabazuing et al. (2017) reveal a bidirectional interplay between pathways leading to apoptosis and pyroptosis, two forms of regulated cell death with opposing inflammatory outcomes. The outcome is sealed by differential cleavage of the key pyroptosis execution substrate gasdermin D such that inflammatory caspases activate it but apoptotic caspases prevent its activation.
May 18, 2017: Cell Chemical Biology
https://www.readbyqxmd.com/read/28515897/exploitation-promotes-earlier-sex-change-in-a-protandrous-patellid-limpet-patella-aspera-r%C3%A3-ding-1798
#15
Gustavo M Martins, Carla D G Borges, Maria Vale, Pedro A Ribeiro, Rogério R Ferraz, Helen R Martins, Ricardo S Santos, Stephen J Hawkins
Exploitation of organisms can prompt the reduction in the number and size of target populations consequently affecting reproductive output and replenishment. Here, we investigated the effects of exploitation on the population structure of a protandrous patellid limpet, Patella aspera, an overexploited Macaronesian endemic. Timed dives were used to collect animals across eleven islands of Macaronesia. Individuals were inspected for sex, size, and gonad stage. Using catch effort (time per person) per island coastal perimeter as a surrogate for exploitation intensity, we found that limpet abundance (CPUE) and mean size tended to decrease with exploitation intensity...
May 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28515501/ismp-medication-error-report-analysis-potential-issues-with-new-basal-insulin-glp-1-fixed-combinations-hydroxyzine-hydroxyurea-mix-up-concomitant-use-of-entresto-and-ace-inhibitors-can-lead-to-serious-outcomes-more-outpatient-oral-cancer-drugs-should-be-in
#16
Michael R Cohen, Judy L Smetzer
These medication errors have occurred in health care facilities at least once. They will happen again-perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided. You should consider publishing accounts of errors in your newsletters and/or presenting them at your inservice training programs. Your assistance is required to continue this feature. The reports described here were received through the Institute for Safe Medication Practices (ISMP) Medication Errors Reporting Program...
April 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/28515431/early-onset-of-nucleate-boiling-on-gas-covered-biphilic-surfaces
#17
Biao Shen, Masayuki Yamada, Sumitomo Hidaka, Jiewei Liu, Junichiro Shiomi, Gustav Amberg, Minh Do-Quang, Masamichi Kohno, Koji Takahashi, Yasuyuki Takata
For phase-change cooling schemes for electronics, quick activation of nucleate boiling helps safeguard the electronics components from thermal shocks associated with undesired surface superheating at boiling incipience, which is of great importance to the long-term system stability and reliability. Previous experimental studies show that bubble nucleation can occur surprisingly early on mixed-wettability surfaces. In this paper, we report unambiguous evidence that such unusual bubble generation at extremely low temperatures-even below the boiling point-is induced by a significant presence of incondensable gas retained by the hydrophobic surface, which exhibits exceptional stability even surviving extensive boiling deaeration...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28513402/safeguarding-adults-in-nursing-practice-second-edition-northway-ruth-jenkins-robert-safeguarding-adults-in-nursing-practice-second-edition-240pp-%C3%A2-21-99-learning-matters-sage-9781473954847-1473954843-formula-see-text
#18
(no author information available yet)
It is refreshing to find a book that explores nursing practice and adult safeguarding in the manner that this one does.
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28509518/the-dental-public-health-implications-of-cosmetic-dentistry-a-scoping-review-of-the-literature
#19
J Doughty, R Lala, Z Marshman
INTRODUCTION: The popularity of cosmetic surgery has seen a rapid increase recently, with the trend mirrored in dentistry. The Department of Health expressed concerns about the potential for biological and psychosocial harm of these cosmetic procedures. Furthermore, the dental public health implications (DPH) of the growing uptake of cosmetic dental procedures have not been explored. OBJECTIVES: Conduct a scoping review to explore the DPH implications of cosmetic dentistry and identify gaps for future research...
September 2016: Community Dental Health
https://www.readbyqxmd.com/read/28508891/joint-morphogenetic-cells-in-the-adult-mammalian-synovium
#20
Anke J Roelofs, Janja Zupan, Anna H K Riemen, Karolina Kania, Sharon Ansboro, Nathan White, Susan M Clark, Cosimo De Bari
The stem cells that safeguard synovial joints in adulthood are undefined. Studies on mesenchymal stromal/stem cells (MSCs) have mainly focused on bone marrow. Here we show that lineage tracing of Gdf5-expressing joint interzone cells identifies in adult mouse synovium an MSC population largely negative for the skeletal stem cell markers Nestin-GFP, Leptin receptor and Gremlin1. Following cartilage injury, Gdf5-lineage cells underpin synovial hyperplasia through proliferation, are recruited to a Nestin-GFP(high) perivascular population, and contribute to cartilage repair...
May 16, 2017: Nature Communications
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