keyword
MENU ▼
Read by QxMD icon Read
search

safeguarding

keyword
https://www.readbyqxmd.com/read/28727912/multivariate-analysis-for-quantification-of-plutonium-iv-in-nitric-acid-based-on-absorption-spectra
#1
Amanda M Lines, Susan R Adami, Sergey I Sinkov, Gregg J Lumetta, Samuel A Bryan
Development of more effective, reliable, and fast methods for monitoring process streams is a growing opportunity for analytical applications. Many fields can benefit from on-line monitoring, including the nuclear fuel cycle where improved methods for monitoring radioactive materials will facilitate maintenance of proper safeguards and ensure safe and efficient processing of materials. On-line process monitoring with a focus on optical spectroscopy can provide a fast, non-destructive method for monitoring chemical species...
July 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28725366/vegetation-structure-and-photosynthesis-respond-rapidly-to-restoration-in-young-coastal-fens
#2
Anna M Laine, Anne Tolvanen, Lauri Mehtätalo, Eeva-Stiina Tuittila
Young coastal fens are rare ecosystems in the first stages of peatland succession. Their drainage compromises their successional development toward future carbon (C) reservoirs. We present the first study on the success of hydrological restoration of young fens. We carried out vegetation surveys at six young fens that represent undrained, drained, and restored management categories in the Finnish land uplift coast before and after restoration. We measured plant level carbon dioxide (CO2) assimilation and chlorophyll fluorescence (Fv/Fm) from 17 most common plant species present at the sites...
October 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/28722656/corrupting-the-dna-damage-response-a-critical-role-for-rad52-in-tumor-cell-survival
#3
Rachel Lieberman, Ming You
The DNA damage response enables cells to survive, maintain genome integrity, and to safeguard the transmission of high-fidelity genetic information. Upon sensing DNA damage, cells respond by activating this multi-faceted DNA damage response leading to restoration of the cell, senescence, programmed cell death, or genomic instability if the cell survives without proper repair. However, unlike normal cells, cancer cells maintain a marked level of genomic instability. Because of this enhanced propensity to accumulate DNA damage, tumor cells rely on homologous recombination repair as a means of protection from the lethal effect of both spontaneous and therapy-induced double-strand breaks (DSBs) in DNA...
July 15, 2017: Aging
https://www.readbyqxmd.com/read/28722026/reconciling-irrigated-food-production-with-environmental-flows-for-sustainable-development-goals-implementation
#4
Jonas Jägermeyr, Amandine Pastor, Hester Biemans, Dieter Gerten
Safeguarding river ecosystems is a precondition for attaining the UN Sustainable Development Goals (SDGs) related to water and the environment, while rigid implementation of such policies may hamper achievement of food security. River ecosystems provide life-supporting functions that depend on maintaining environmental flow requirements (EFRs). Here we establish gridded process-based estimates of EFRs and their violation through human water withdrawals. Results indicate that 41% of current global irrigation water use (997 km(3) per year) occurs at the expense of EFRs...
July 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/28716051/mir-380-5p-mediated-repression-of-tep1-and-tspyl5-interferes-with-telomerase-activity-and-favours-the-emergence-of-an-alt-like-phenotype-in-diffuse-malignant-peritoneal-mesothelioma-cells
#5
Graziella Cimino-Reale, Paolo Gandellini, Francesca Santambrogio, Marta Recagni, Nadia Zaffaroni, Marco Folini
BACKGROUND: Understanding the molecular/cellular underpinnings of diffuse malignant peritoneal mesothelioma (DMPM), a fatal malignancy with limited therapeutic options, is of utmost importance for the fruitful management of the disease. In this context, we previously found that telomerase activity (TA), which accounts for the limitless proliferative potential of cancer cells, is prognostic for disease relapse and cancer-related death in DMPM patients. Consequently, the identification of factors involved in telomerase activation/regulation may pave the way towards the development of novel therapeutic interventions for the disease...
July 17, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28712160/perspectives-on-childhood-resilience-among-the-aboriginal-community-an-interview-study
#6
Christian Young, Allison Tong, Janice Nixon, Peter Fernando, Deanna Kalucy, Simone Sherriff, Kathleen Clapham, Jonathan C Craig, Anna Williamson
OBJECTIVE: To describe Aboriginal community members' perspectives on the outcomes and origins of resilience among Aboriginal children. METHODS: Face-to-face interviews were conducted with 36 Aboriginal adults (15 health service professionals, 8 youth workers and 13 community members) at two urban and one regional Aboriginal Community Controlled Health Service in New South Wales. Interviews were transcribed and analysed thematically. RESULTS: We identified six themes: withstanding risk (displaying normative development, possessing inner fortitude); adapting to adversity (necessary endurance, masking inner vulnerabilities); positive social influences (secure family environments, role modelling healthy behaviours and relationships); instilling cultural identity (investing in Aboriginal knowledge, building a strong cultural self-concept); community safeguards (offering strategic sustainable services, holistic support, shared responsibility, providing enriching opportunities); and personal empowerment (awareness of positive pathways, developing self-respect, fostering positive decision making)...
July 16, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28711989/striking-the-right-immunological-balance-prevents-progression-of-tuberculosis
#7
REVIEW
Shachi Pranjal Vyas, Ritobrata Goswami
INTRODUCTION: Tuberculosis (TB) caused by infection with Mycobacterium tuberculosis (Mtb) is a major burden for human health worldwide. Current standard treatments for TB require prolonged administration of antimycobacterial drugs leading to exaggerated inflammation and tissue damage. This can result in the reactivation of latent TB culminating in TB progression. Thus, there is an unmet need to develop therapies that would shorten the duration of anti-TB treatment and to induce optimal protective immune responses to control the spread of mycobacterial infection with minimal lung pathology...
July 15, 2017: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/28705114/genetic-changes-of-mlh1-and-msh2-genes-could-explain-constant-findings-on-microsatellite-instability-in-intracranial-meningioma
#8
Nives Pećina-Šlaus, Anja Kafka, Anja Bukovac, Tomislav Vladušić, Davor Tomas, Reno Hrašćan
Postreplicative mismatch repair safeguards the stability of our genome. The defects in its functioning will give rise to microsatellite instability. In this study, 50 meningiomas were investigated for microsatellite instability. Two major mismatch repair genes, MLH1 and MSH2, were analyzed using microsatellite markers D1S1611 and BAT26 amplified by polymerase chain reaction and visualized by gel electrophoresis on high-resolution gels. Furthermore, genes DVL3 (D3S1262), AXIN1 (D16S3399), and CDH1 (D16S752) were also investigated for microsatellite instability...
July 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28700931/feedback-inhibition-of-the-rag-gtpase-gap-complex-lst4-lst7-safeguards-torc1-from-hyperactivation-by-amino-acid-signals
#9
Marie-Pierre Péli-Gulli, Serena Raucci, Zehan Hu, Jörn Dengjel, Claudio De Virgilio
Amino acids stimulate the eukaryotic target of rapamycin complex 1 (TORC1), and hence growth, through the Rag GTPases and their regulators. Among these, the yeast Lst4-Lst7 Rag GTPase GAP complex clusters, as we previously reported, at the vacuolar membrane upon amino acid starvation. In response to amino acid refeeding, it activates the Rag GTPase-TORC1 branch and is then dispersed from the vacuolar surface. Here, we show that the latter effect is driven by TORC1 itself, which directly phosphorylates several residues within the intra-DENN loop of Lst4 that, only in its non-phosphorylated state, tethers the Lst4-Lst7 complex to the vacuolar membrane...
July 11, 2017: Cell Reports
https://www.readbyqxmd.com/read/28700187/-safety-regulations-in-the-healthcare-workplaces
#10
REVIEW
Mauro Marin, Giulia Marin
The law n. 81/2008 gathers the regulations about the health safeguard and safety in the workplaces. It provides the duty of risk management, the designation of a responsible for the prevention and protection services, the designation of a specialist doctor for the surveillance of the operators and of the workplaces and a training focused on safety for all the operators. In the healthcare workplaces usually we can distinguish between the risks for the workers safety and the risks for the workers health. The art...
June 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28697285/an-expert-elicitation-of-the-proliferation-resistance-of-using-small-modular-reactors-smr-for-the-expansion-of-civilian-nuclear-systems
#11
Jonas Siegel, Elisabeth A Gilmore, Nancy Gallagher, Steve Fetter
To facilitate the use of nuclear energy globally, small modular reactors (SMRs) may represent a viable alternative or complement to large reactor designs. One potential benefit is that SMRs could allow for more proliferation resistant designs, manufacturing arrangements, and fuel-cycle practices at widespread deployment. However, there is limited work evaluating the proliferation resistance of SMRs, and existing proliferation assessment approaches are not well suited for these novel arrangements. Here, we conduct an expert elicitation of the relative proliferation resistance of scenarios for future nuclear energy deployment driven by Generation III+ light-water reactors, fast reactors, or SMRs...
July 11, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28695703/a-cross-sectional-study-investigating-patient-centred-care-co-creation-of-care-well-being-and-job-satisfaction-among-nurses
#12
Judith den Boer, Anna P Nieboer, Jane M Cramm
BACKGROUND: Developments in the community health nursing sector have resulted in many changes in the activities of these nurses. The concepts of patient-centred care and co-creation of care are gaining importance in the work of community health nurses. Whether patient-centred care also contributes positively to nurses' well-being and job satisfaction is not known. METHOD: In 2015, a cross-sectional survey was conducted among 153 community health nurses employed by 11 health care organisations in the southern part of the Netherlands...
July 11, 2017: Journal of Nursing Management
https://www.readbyqxmd.com/read/28694641/medicine-revisited-safeguard-yourself-against-oblivious-to-the-obvious
#13
Sachin A Adukia, Gopal Krishna Dash
No abstract text is available yet for this article.
July 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28692904/emerging-roles-of-the-histone-chaperone-caf-1-in-cellular-plasticity
#14
REVIEW
Sihem Cheloufi, Konrad Hochedlinger
During embryonic development, cells become progressively restricted in their differentiation potential. This is thought to be regulated by dynamic changes in chromatin structure and associated modifications, which act together to stabilize distinct specialized cell lineages. Remarkably, differentiated cells can be experimentally reprogrammed to a stem cell-like state or to alternative lineages. Thus, cellular reprogramming provides a valuable platform to study the mechanisms that normally safeguard cell identity and uncover factors whose manipulation facilitates cell fate transitions...
July 7, 2017: Current Opinion in Genetics & Development
https://www.readbyqxmd.com/read/28692422/mitochondrial-flashes-regulate-atp-homeostasis-in-the-heart
#15
Xianhua Wang, Xing Zhang, Di Wu, Zhanglong Huang, Tingting Hou, Chongshu Jian, Peng Yu, Fujian Lu, Rufeng Zhang, Tao Sun, Jinghang Li, Wenfeng Qi, Yanru Wang, Feng Gao, Heping Cheng
The maintenance of a constant ATP level ('set-point') is a vital homeostatic function shared by eukaryotic cells. In particular, mammalian myocardium exquisitely safeguards its ATP set-point despite 10-fold fluctuations in cardiac workload. However, the exact mechanisms underlying this regulation of ATP homeostasis remain elusive. Here we show mitochondrial flashes (mitoflashes), recently discovered dynamic activity of mitochondria, play an essential role for the auto-regulation of ATP set-point in the heart...
July 10, 2017: ELife
https://www.readbyqxmd.com/read/28689628/preventing-violence-exploitation-and-abuse-of-persons-with-mental-disabilities-exploring-the-monitoring-implications-of-article-16-of-the-united-nations-convention-on-the-rights-of-persons-with-disabilities
#16
Judy Laing
Article 16 of the United Nations Convention on the Rights of Persons with Disabilities includes the right to be free from all forms of violence, exploitation and abuse. In pursuance of this aim, Article 16 (3) imposes an obligation on States Parties to 'ensure that all facilities and programmes designed to serve persons with disabilities are effectively monitored by independent authorities'. Effective independent monitoring is viewed as a key mechanism to help safeguard people from violence, exploitation and abuse...
July 6, 2017: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/28688334/-behind-closed-doors-with-open-minds-a-qualitative-study-exploring-nursing-home-staff-s-narratives-towards-their-roles-and-duties-within-the-context-of-sexuality-in-dementia
#17
T Vandrevala, T Chrysanthaki, E Ogundipe
BACKGROUND: Despite sexual expression being recognised as a fundamental human need, sexuality in old age is often ignored and frequently misunderstood, with residents with dementia in a nursing home often viewed as asexual or incapable of being sexually active. OBJECTIVES: The current study aims to understand the views held by nursing care home staff towards dementia and sexuality and explore the roles they may adopt whilst responding and managing sexual needs and expression for residents with dementia...
June 13, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28686151/individual-contextual-and-network-characteristics-of-blood-donors-and-non-donors-a-systematic-review-of-recent-literature
#18
REVIEW
Tjeerd W Piersma, René Bekkers, Elisabeth F Klinkenberg, Wim L A M De Kort, Eva-Maria Merz
BACKGROUND: The ageing population and recent migration flows may negatively affect the blood supply in the long term, increasing the importance of targeted recruitment and retention strategies to address donors. This review sought to identify individual, network and contextual characteristics related to blood donor status and behaviour, to systematically discuss differences between study results, and to identify possible factors to target in recruitment and retention efforts. METHODS: The systematic review was conducted in accordance with a predefined PROSPERO protocol (CRD42016039591)...
June 13, 2017: Blood Transfusion, Trasfusione del Sangue
https://www.readbyqxmd.com/read/28686103/reporting-deaths-to-the-coroner
#19
Richard Griffith
The Chief Coroner has issued new guidance in relation to death where the person is subject to a deprivation of liberty safeguards standard authorisation ( Chief Coroner, 2017 ). In this article, Richard Griffith discusses the impact of the Police and Crime Act 2017, section 178 on the need to report deaths of patients' subject to a deprivation of liberty safeguards standard authorisation to the coroner.
July 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28685183/-critical-endothelial-procedures-during-posterior-lamellar-graft-preparation-and-transplantation
#20
REVIEW
T A Fuchsluger, F E Kruse, G Geerling
BACKGROUND: In view of the very low proliferation rate and functional importance of the corneal endothelium in maintaining corneal transparency, safeguarding the integrity of this monolayer plays a central role in posterior lamellar corneal transplantation. Several critical endothelial procedural stages are necessary to carry out such a transplantation. OBJECTIVE: This article presents various preparatory and operative approaches for carrying out the necessary and critical stages within the framework of posterior lamellar corneal transplantation and concentrates on the question of optimization...
July 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
keyword
keyword
101508
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"