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https://www.readbyqxmd.com/read/28438320/critical-care-nurses-perceptions-of-the-outcomes-of-working-overtime-in-canada
#1
Vanessa M Lobo, Jenny Ploeg, Anita Fisher, Gladys Peachey, Noori Akhtar-Danesh
BACKGROUND: Nursing overtime is being integrated into the normal landscape of practice to ensure optimal staffing levels and addresses variations in patient volume and acuity. This is particularly true in critical care where fluctuations in either are difficult to predict. PURPOSE: The goal of this study was to explore critical care nurses' perceptions of the outcomes of working overtime. METHODS: Sally Thorne's interpretive description guided the collection and analysis of data...
January 7, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28437005/convergent-erk1-2-p38-and-jnk-mapk-signalling-mediate-catecholoestradiol-induced-proliferation-of-ovine-uterine-artery-endothelial-cells
#2
Rosalina Villalon Landeros, Sheikh O Jobe, Gabrielle Aranda-Pino, Gladys E Lopez, Jing Zheng, Ronald R Magness
Previously we demonstrated that the biologically active metabolites of 17β-oestradiol, 2-hydroxyoestradiol (2-OHE2 ) and 4-hydroxyoestradiol (4-OHE2 ), stimulate pregnancy-specific proliferation of uterine artery endothelial cells derived from pregnant (P-UAECs), but not non-pregnant ewes. However, unlike 17β-oestradiol, which induces proliferation via oestrogen receptor-β (ER-β), the catecholoestradiols mediate P-UAEC proliferation via β-adrenoceptors (β-AR) and independent of classic oestrogen receptors...
April 24, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28434690/assessment-of-potential-mirna-biomarkers-of-vero-cell-tumorigenicity-in-a-new-line-agmk1-9t7-of-african-green-monkey-kidney-cells
#3
Belete Teferedegne, Daniel M Rotroff, Juliete Macauley, Gideon Foseh, Gladys Lewis, Alison Motsinger-Rief, Andrew M Lewis
Patterns of microRNA expression appear to delineate the process of spontaneous neoplastic development-transformation (SPNDT) occurring in the African green monkey kidney (AGMK) VERO cell line (Teferedegne et al., 2010). Analysis of microarray data identified 6 microRNAs whose high-level of expression peaked when the World Health Organization 10-87 VERO cells became tumorigenic at passage (p) 190. Six miRNAs were identified as potential biomarkers for the expression of the VERO-cell tumorigenic phenotype (Teferedegne et al...
April 20, 2017: Vaccine
https://www.readbyqxmd.com/read/28434476/a-qualitative-approach-exploring-the-acceptability-of-yoga-for-minorities-living-with-arthritis-where-are-the-people-who-look-like-me
#4
Kimberly R Middleton, Miriam Magaña López, Steffany Haaz Moonaz, Gladys Tataw-Ayuketah, Michael M Ward, Gwenyth R Wallen
OBJECTIVES: To examine the acceptability of yoga research tailored to recruit and retain a minority population (both English and Spanish speaking) with arthritis. Yoga research for arthritis often underrepresents minorities and acceptability for this population has not previously been investigated. DESIGN: Acceptability was evaluated using retention, adherence, journals, and semi-structured exit interviews from twelve participants with osteoarthritis or rheumatoid arthritis undergoing an 8-week yoga intervention...
April 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28426892/-i-am-still-passionate-despite-the-challenges-nurses-navigating-the-care-for-refugees
#5
Olayide Ogunsiji, Harrison Ng Chok, Gladys Mashingaidze, Lesley Wilkes
AIMS AND OBJECTIVES: The aim of this study is to report the challenges faced by the nursing workforce in refugee health. BACKGROUND: Nurses are in the forefront of care provision for refugees who are recognised as one of the most vulnerable population groups in the world. The number of refugees in Australia is increasing and more nurses are needed as care providers. Research on the challenges faced by refugee health nurses is sparse. DESIGN: Qualitative research methodology was used to study the experience of refugee health nurses...
April 20, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28421801/actitudes-de-escolares-chilenos-de-distinto-nivel-socioecon%C3%A3-mico-al-inicio-de-la-implementaci%C3%A3-n-de-la-ley-que-regula-la-venta-y-publicidad-de-alimentos-altos-en-nutrientes-cr%C3%A3-ticos
#6
Sonia Olivares Cortes, Jacqueline Araneda Flores, Gladys Morales Illanes, Bárbara Leyton Dinamarca, Nelly Bustos Zapata, María Angélica Hernández Moreno, María Teresa Oyarzún Macchiavello
Introducción: el 27 de junio de 2016 se implementó en Chile la Ley sobre Composición Nutricional de los Alimentos y su Publicidad, que implica rotular el envase de los alimentos procesados, altos en calorías, grasas saturadas, azúcares y sodio.Objetivo: determinar las actitudes de escolares de 8 a 12 años, de distinto nivel socioeconómico (NSE) y estado nutricional, ante el nuevo etiquetado de los alimentos.Métodos: se aplicó una encuesta validada previamente, agregando preguntas sobre los nuevos sellos en los envases de alimentos y bebidas...
March 30, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28420401/using-media-to-impact-health-policy-making-an-integrative-systematic-review
#7
REVIEW
Lama Bou-Karroum, Fadi El-Jardali, Nour Hemadi, Yasmine Faraj, Utkarsh Ojha, Maher Shahrour, Andrea Darzi, Maha Ali, Carine Doumit, Etienne V Langlois, Jad Melki, Gladys Honein AbouHaidar, Elie A Akl
INTRODUCTION: Media interventions can potentially play a major role in influencing health policies. This integrative systematic review aimed to assess the effects of planned media interventions-including social media-on the health policy-making process. METHODS: Eligible study designs included randomized and non-randomized designs, economic studies, process evaluation studies, stakeholder analyses, qualitative methods, and case studies. We electronically searched Medline, EMBASE, Communication and Mass Media Complete, Cochrane Central Register of Controlled Trials, and the WHO Global Health Library...
April 18, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28418539/ophthalmic-manifestations-of-congenital-zika-syndrome-in-colombia-and-venezuela
#8
Juan B Yepez, Felipe A Murati, Michele Pettito, Carlos F Peñaranda, Jazmin de Yepez, Gladys Maestre, J Fernando Arevalo
Importance: The ocular manifestations and sequelae of Zika virus infection are not well known. Recently, the World Health Organization changed the declaration of Zika as a public health emergency and designated the viral outbreak and related microcephaly clusters as a long-term program of work. This change indicates the urgent need to evaluate and document ophthalmic manifestations in patients for timely management of this disease. In addition, confirmation whether the public health problem in Brazil extends to other regions in South America is needed...
April 13, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28417995/corrigendum-do-primary-care-provider-strategies-improve-patient-participation-in-colorectal-cancer-screening
#9
Nancy N Baxter, Rinku Sutradhar, Qing Li, Corinne Daly, Gladys N Honein-AbouHaidar, Devon P Richardson, Lisa Del Giudice, Jill Tinmouth, Lawrence Paszat, Linda Rabeneck
No abstract text is available yet for this article.
April 18, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28416707/distinct-domains-confer-chea-with-unique-functions-in-chemotaxis-and-cell-length-in-azospirillum-brasilense-sp7
#10
Jessica M Gullett, Amber Bible, Gladys Alexandre
Chemotaxis is the movement of cells in response to gradients of diverse chemical cues. Motile bacteria utilize a conserved chemotaxis signal transduction system to bias their motility and navigate through a gradient. A central regulator of chemotaxis is the histidine kinase, CheA. This cytoplasmic protein interacts with membrane-bound receptors, which assemble into large polar arrays, to propagate the signal. In the alphaproteobacterium, Azospirillum brasilense, Che1 controls transient increases in swimming speed during chemotaxis, but it also biases the cell length at division...
April 17, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28414583/improved-depressive-symptoms-in-adults-with-schizophrenia-during-a-smoking-cessation-attempt-with-varenicline-and-behavioral-therapy
#11
Corinne Cather, Susanne Hoeppner, Gladys Pachas, Sarah Pratt, Eric Achtyes, Kristina M Cieslak, A Eden Evins
OBJECTIVE: Smoking prevalence rates are elevated in individuals with schizophrenia spectrum disorders (SSD) compared with the general population, with attendant disproportionate smoking-related morbidity and mortality. Pharmacotherapies that improve abstinence rates in this population are underutilized, partly due to concerns about neuropsychiatric safety, particularly for those with comorbid depression or prior suicide attempt. Prospective assessment of the psychiatric safety profile of varenicline in those with SSD is needed...
April 17, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/28410356/water-exposure-is-a-common-risk-behavior-among-soft-and-gas-permeable-contact-lens-wearers
#12
Aaron B Zimmerman, Kathryn Richdale, Gladys Lynn Mitchell, Beth T Kinoshita, Dawn Y Lam, Heidi Wagner, Luigina Sorbara, Robin L Chalmers, Sarah A Collier, Jennifer R Cope, Maya M Rao, Michael J Beach, Jonathan S Yoder
PURPOSE: To understand soft contact lens (SCL) and gas-permeable (GP) lens wearers' behaviors and knowledge regarding exposure of lenses to water. METHODS: The Contact Lens Risk Survey (CLRS) and health behavior questions were completed online by a convenience sample of 1056 SCL and 85 GP lens wearers aged 20 to 76 years. Participants were asked about exposing their lenses to water and their understanding of risks associated with these behaviors. Chi-square analyses examined relationships between patient behaviors and perceptions...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28407546/exploring-adduct-formation-between-human-serum-albumin-and-eleven-organophosphate-ester-flame-retardants-and-plasticizers-using-maldi-tof-tof-and-lc-q-tof
#13
Shaogang Chu, Margaret R Baker, Gladys Leong, Robert J Letcher, Shirley J Gee, Bruce D Hammock, Qing X Li
Organophosphate (OP) and organophosphate ester (OPE) adducts of albumin are valuable biomarkers for retrospective verification of exposure. In the present study, our goal was to determine whether OPE flame retardants (OPE FRs) and OPE plasticizers can covalently bind to human serum albumin (HSA), which would allow the resulting adducts to be used to evaluate exposure. Eleven OPE FRs and plasticizers were examined in a HSA-adduct in vitro assay. Pure HSA was incubated with the target OPEs, as well as with an OP insecticide (profenofos) positive control...
March 31, 2017: Chemosphere
https://www.readbyqxmd.com/read/28405918/hepcidin-suppression-in-%C3%AE-thalassemia-is-associated-with-the-down-regulation-of-atonal-homolog-8
#14
Supranee Upanan, Andrew T McKie, Gladys O Latunde-Dada, Sittiruk Roytrakul, Chairat Uthaipibull, Peraphan Pothacharoen, Prachya Kongtawelert, Suthat Fucharoen, Somdet Srichairatanakool
Atonal homolog 8 (ATOH8) is defined as a positive regulator of hepcidin transcription, which links erythropoietic activity with iron-sensing molecules. In the present study, we investigated the association between hepcidin and ATOH8 expression in β-thalassemia. We found that inhibition of hepcidin expression in β-thalassemia is correlated with reduced ATOH8 expression. Hepatic hepcidin 1 (Hamp1) and Atoh8 mRNA expression were down-regulated in β-thalassemic mice. Hepcidin (HAMP) and ATOH8 mRNA expression were consistently suppressed in Huh7 cells cultured in medium supplemented with β-thalassemia patient serum...
April 12, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/28399271/high-prevalence-of-rickettsia-spp-in-dog-fleas-siphonaptera-pulicidae-in-rural-uganda
#15
Ana M Palomar, Aitor Cevidanes, Aránzazu Portillo, Gladis Kalema-Zikusoka, Andrea D Chirife, Lourdes Romero, Jesús Muro, Lawrence Mugisha, José A Oteo, Javier Millán
Fleas are known vectors of zoonotic agents. Thirty-five fleas, including 28 Ctenocephalides felis (Bouché), four Pulex irritans (L.), and three Echidnophaga gallinacea (Westwood) from 19 rural dogs from southwestern Uganda were analyzed for the presence of Rickettsia spp. (ompB, gltA, and 17 kDa fragment genes) and Bartonella spp. (rpoB and ITS genes) by PCR. Rickettsial DNA was detected in 27 out of 28 of Ct. felis and in two out of four P. irritans. None of the E. gallinacea specimens harbored Rickettsia DNA...
March 23, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28395333/ovine-uterine-space-restriction-causes-dysregulation-of-the-renin-angiotensin-system-in-fetal-kidneys%C3%A2
#16
Rachel A Kranch-Shorthouse, Adam S Bauer, Ronald R Magness, Gladys E Lopez, Jeffrey L Segar, Sharon E Blohowiak, Pamela J Kling
In ovine pregnancy, uterine space restriction (USR) resulting from decreased space for placental attachment caused intrauterine growth restriction and impaired nephrogenesis. The fetal kidney renin-angiotensin system (RAS) is involved in nephrogenesis, fluid balance, and iron deposition. Angiotensin II exerts its effects via multiple receptors: angiotensin II 1-8 receptor type 1 (AT 1 R) and type 2 (AT 2 R), and angiotensin II 1-7 Mas receptor (MASR). Objective: : To test the hypothesis that ovine USR is associated with dysregulation of the fetal renal RAS...
January 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28394953/-27-hydroxycholesterol-reverses-estradiol-induced-inhibition-of-platelet-aggregation-in-postmenopausal-women
#17
Gladys Rocha, Walter Sierralta, Luis Valladares
BACKGROUND: The decline of estrogen levels increases cardiovascular risk in women. Platelets express estrogen receptors and 17β-estradiol- (E2) can produce a protective effect on thrombus formation. The hydroxylation of cholesterol generates several sterols and 27-hydroxycholesterol (27HC) predominates in circulation. AIM: To evaluate the effect of 27HC as an endogenous antagonist of the anti-aggregating properties of E2 in platelets of postmenopausal women. MATERIAL AND METHODS: Platelet function of postmenopausal women was evaluated ex-vivo...
November 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28388838/trauma-exposure-among-women-in-the-pacific-rim
#18
Elizabeth Reeves, Pilar Bernal de, Susan G Silva, Diva Jaramillo, Tulia Uribe, Agnes Tiwari, Gladys Eugenia Canaval, Maria Eugenia Mendoza Flores, Ruth Ann Belknap, Janice C Humphreys
PURPOSE: Healthcare professionals who provide services in the immediate or long-term aftermath of traumatic events need to understand the nature and frequency of traumatic events in the lives of women. However, research on trauma exposure in women has only recently begun to assess events other than intimate partner and sexual violence and has not supported direct statistical comparison of cross-national and cross-cultural data. The purpose of this descriptive, correlational study was to describe and compare trauma exposure prevalence and type in community-based samples of women in the United States, Colombia, and Hong Kong...
April 7, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28385574/ouabain-promotes-partial-epithelial-to-mesenchymal-transition-emt-changes-in-human-autosomal-dominant-polycystic-kidney-disease-adpkd-cells
#19
Jessica Venugopal, Jeffrey McDermott, Gladis Sanchez, Madhulika Sharma, Leandro Barbosa, Gail A Reif, Darren P Wallace, Gustavo Blanco
The hormone ouabain has been shown to enhance the cystic phenotype of autosomal dominant polycystic kidney disease (ADPKD). Among other characteristics, the ADPKD phenotype includes cell de-differentiation and epithelial to mesenchymal transition (EMT). Here, we determined whether physiological concentrations of ouabain induces EMT in human renal epithelial cells from patients with ADPKD. We found that ADPKD cells respond to ouabain with a decrease in expression of the epithelial marker E-cadherin and increase in the expression of the mesenchymal markers N-cadherin, α smooth muscle actin (αSMA) and collagen-I; and the tight junction protein occludin and claudin-1...
April 3, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28379731/local-outbreak-of-listeria-monocytogenes-serotype-4b-sequence-type-6-due-to-contaminated-meat-p%C3%A3-t%C3%A3
#20
Denise Althaus, Marco Jermini, Petra Giannini, Gladys Martinetti, Danuta Reinholz, Magdalena Nüesch-Inderbinen, Angelika Lehner, Roger Stephan
In January and February 2016, five cases of confirmed and two cases of probable infection due to Listeria monocytogenes serotype 4b, sequence type (ST) 6 belonging to a single pulsed-field gel electrophoresis pulsotype pattern were registered in a region of southern Switzerland. L. monocytogenes was detected in blood samples (four cases) and pleural fluid (one case). Furthermore, L. monocytogenes 4b ST6 was detected in a stool sample of an asymptomatic person exposed to a common food. Forthwith, the food safety authority and a local gourmet meat producer reported L...
April 2017: Foodborne Pathogens and Disease
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