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cervical instability

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https://www.readbyqxmd.com/read/28816881/the-shikani-optical-stylet-as-an-alternative-to-awake-fiberoptic-intubation-in-patients-at-risk-of-secondary-cervical-spine-injury-a-randomized-controlled-trial
#1
Rabab S S Mahrous, Aly M M Ahmed
BACKGROUND: Conventional intubation of the trachea and consequent prone positioning of anesthetized patients with cervical spine instability may result in secondary neurological injury. Historically, flexible fiberoptics used to be the chief choice for patients presenting with cervical spine instability surgery with difficult airway. Recently, the rigid optical stylets have shown promise in assisting difficult intubations. PURPOSE: The aim of the present study was to compare the efficacy of Shikani optical stylet (SOS) with the flexible fiberscope for awake intubation in patients with cervical spine instability...
August 14, 2017: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/28799855/surgical-management-of-cervical-spine-deformity-in-chondrodysplasia-punctata
#2
Nobuhito Morota, Satoshi Ihara, Hideki Ogiwara, Goichiro Tamura
OBJECTIVE Chondrodysplasia punctata (CDP), a rare skeletal dysplasia, can lead to cervical spine instability and deformity. However, an optimal neurosurgical intervention has yet to be established. Thus, a retrospective study was conducted to assess the efficacy of various surgical interventions for children with CDP. METHODS The authors retrospectively reviewed 9 cases of CDP in which cervical decompression with or without posterior fusion was performed between April 2007 and May 2016. Patient demographics, preoperative clinical conditions, radiographic findings, surgical procedures, and the postoperative course were analyzed in detail...
August 11, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28795009/evaluation-and-management-of-shoulder-pain-in-skeletally-immature-athletes
#3
REVIEW
Dilip R Patel, Stephen Breisach
Shoulder pain in young athletes generally is a result of poor sports technique and overuse. A number intrinsic causes of shoulder pain have been identified. Pain may also be referred to shoulder area from cervical spine, neck and chest pathology. Overuse stress injury of the proximal humeral physis is important to recognize early in order to prevent later complications. Shoulder impingement syndrome is a general term used to describe multiple underlying lesions and relatively uncommon in young athletes. In adolescent athletes, glenohumeral instability is an important underlying pathomechanical basis for shoulder pain...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28771191/somatic-host-cell-alterations-in-hpv-carcinogenesis
#4
REVIEW
Tamara R Litwin, Megan A Clarke, Michael Dean, Nicolas Wentzensen
High-risk human papilloma virus (HPV) infections cause cancers in different organ sites, most commonly cervical and head and neck cancers. While carcinogenesis is initiated by two viral oncoproteins, E6 and E7, increasing evidence shows the importance of specific somatic events in host cells for malignant transformation. HPV-driven cancers share characteristic somatic changes, including apolipoprotein B mRNA editing catalytic polypeptide-like (APOBEC)-driven mutations and genomic instability leading to copy number variations and large chromosomal rearrangements...
August 3, 2017: Viruses
https://www.readbyqxmd.com/read/28768872/high-risk-alpha-papillomavirus-oncogenes-impair-the-homologous-recombination-pathway
#5
Nicholas A Wallace, Sujita Khanal, Kristin L Robinson, Sebastian O Wendel, Joshua J Messer, Denise A Galloway
Persistent high risk genus α human papillomavirus (HPV) infections cause nearly every cervical carcinoma and a subset of tumors in the oropharyngeal tract. During the decades required for HPV-associated tumorigenesis, the cellular genome becomes significantly destabilized. Our analysis of cervical tumors from 4 separate data sets found a significant upregulation of the homologous recombination (HR) pathway genes. The increased abundance of HR proteins can be replicated in primary cells by expression of the two HPV oncogenes (E6 and E7) required for HPV-associated transformation...
August 2, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28761503/there-is-no-evidence-that-laminoplasty-results-in-improved-outcomes-compared-with-laminectomy-in-cervical-spinal-cord-injury-without-instability
#6
COMMENT
Shayan Abdollah Zadegan, Vafa Rahimi-Movaghar
No abstract text is available yet for this article.
July 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/28760029/keyhole-approaches-to-intradural-pathologies
#7
Klaus C Mende, Theresa Krätzig, Malte Mohme, Manfred Westphal, Sven O Eicker
OBJECTIVE Spinal tumors account for 2%-4% of all tumors of the central nervous system and can be intramedullary, intradural extramedullary, or extradural. In the past, wide approaches were used to obtain safe access to these tumors, as complete resection is the goal in treating most tumor entities. To reduce surgical complications due to large skin incisions and destabilizing laminectomies, minimally invasive approaches were established. In this study, the authors share their experience with mini-open approaches to intradural tumor pathologies...
August 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28756456/clinical-predictors-of-surgical-outcomes-and-imaging-features-in-single-segmental-cervical-spondylotic-myelopathy-with-lower-cervical-instability
#8
Kuan Lu, Xianda Gao, Tong Tong, Dechao Miao, Wenyuan Ding, Yong Shen
BACKGROUND Cervical degenerative changes are the most common cause of cervical spondylotic myelopathy (CSM) and lower cervical instability (LCI). The purpose of this study was to investigate the associated factors of MRI signal changes and prognosis in single segmental CSM accompanied by LCI. MATERIAL AND METHODS A total of 122 patients met the inclusion criteria and were enrolled in this study with a minimum follow-up period of 2 years. According to the absence/presence of LCI, patients were divided into the unstable group (n=43 [35...
July 30, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28752246/myelopathy-associated-with-instability-consequent-to-resection-of-ossification-of-anterior-longitudinal-ligament-in-dish
#9
Man-Kyu Park, Kyoung-Tae Kim, Dae-Chul Cho, Joo-Kyung Sung
PURPOSE: The presence of prominent OALL (ossification of anterior longitudinal ligament) in the anterior cervical spine has been implicated as a cause of dysphagia. Surgical resection of the OALL is considered effective for the management of diffuse idiopathic skeletal hyperostosis (DISH)-related dysphagia. Although many reports have been published on DISH-related dysphagia, no cases of postoperative cervical instability have been reported thus far. We present a case in which the patient developed myelopathy associated with instability consequent to resection of OALL in DISH...
July 27, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28739475/posterior-osteosynthesis-with-monoaxial-lateral-mass-screw-rod-system-for-unstable-c1-burst-fractures
#10
Yin-Shun Zhang, Jian-Xiang Zhang, Qing-Guo Yang, Wei Li, Hui Tao, Cai-Liang Shen
BACKGROUND CONTEXT: Surgical treatment for unstable atlas fractures has evolved in recent decades from C1-C2 or C0-C2 fusion to motion-preservation techniques of open reduction and internal fixation (ORIF). However, regardless of transoral or posterior approach, the reduction is still not satisfactory. PURPOSE: The article describes and evaluates a new technique for treating the unstable atlas fractures by using a monoaxial screw-rod system. STUDY DESIGN: This is a retrospective study PATIENT SAMPLE: The sample includes adult patients with unstable C1 fractures treated with a posterior monoaxial screw-rod system...
July 21, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28739045/filamin-b-the-next-hotspot-in-skeletal-research
#11
REVIEW
Qiming Xu, Nan Wu, Lijia Cui, Zhihong Wu, Guixing Qiu
Filamin B (FLNB) is a large dimeric actin-binding protein which crosslinks actin cytoskeleton filaments into a dynamic structure. Up to present, pathogenic mutations in FLNB are solely found to cause skeletal deformities, indicating the important role of FLNB in skeletal development. FLNB-related disorders are classified as spondylocarpotarsal synostosis (SCT), Larsen syndrome (LS), atelosteogenesis (AO), boomerang dysplasia (BD), and isolated congenital talipes equinovarus, presenting with scoliosis, short-limbed dwarfism, clubfoot, joint dislocation and other unique skeletal abnormalities...
July 20, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28735126/multilevel-spinal-segmental-fixation-for-kyphotic-cervical-spinal-deformity-in-pediatric-age-group-report-of-management-in-2-cases
#12
Atul Goel, Amol Kaswa, Abhidha Shah, Arjun Dhar
OBJECTIVE: We discuss the role of instability of multiple segments of spine that includes atlantoaxial joint in pathogenesis of cervical kyphotic deformity. MATERIAL AND METHODS: Two male patients (5 and 17 year old) had severe cervical kyphosis and presented with symptoms related to myelopathy. The patients underwent multi-segmental spinal distraction and fixation that included atlantoaxial joint. No bone decompression was done. RESULTS: At a follow-up of more than 30 months, both patients had significant neurological recovery...
July 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28723737/how-to-choose-when-implants-of-adjacent-height-both-fit-the-disc-space-properly-in-single-level-cervical-artificial-disc-replacement
#13
Xin Rong, Jigang Lou, Huibo Li, Yang Meng, Hao Liu
In cervical artificial disc replacement (C-ADR), sometimes we encountered with such cases that implants of adjacent height both fit the target disc space properly. No study was available discussing the choice of implant height and the clinical outcomes under such circumstance. The purpose of this study was to evaluate the impact of different implant heights on the clinical outcomes and radiographic results when the implants of adjacent height both fit the disc space properly. This retrospective study included 34 patients underwent single-level C-ADR at the C5-C6 level at our institution...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28717061/apobec-mediated-genomic-alterations-link-immunity-and-viral-infection-during-human-papillomavirus-driven-cervical-carcinogenesis
#14
Lanting Chen, Xuemin Qiu, Na Zhang, Yan Wang, Mingyan Wang, Dajin Li, Ling Wang, Yan Du
Cervical cancer is one of the most frequently diagnosed cancers and is a major cause of death from gynecologic cancers worldwide; the cancer burden from cervical cancer is especially heavy in less developed countries. Most cases of cervical cancer are caused by persistent infection with carcinogenic human papillomavirus (HPV) genotypes 16 and 18. Non-resolving inflammation caused by HPV infection provides a microenvironment that facilitates cancer development. Molecular alterations during the process of HPV-induced carcinogenesis are characterized by DNA methylation within the HPV genome, promoter hypermethylation of tumor suppressor genes in the host genome, as well as genomic instability caused by viral DNA integrating into the host genome...
July 17, 2017: Bioscience Trends
https://www.readbyqxmd.com/read/28715333/wheelchair-neuroprosthesis-for-improving-dynamic-trunk-stability
#15
Kramay Patel, Matija Milosevic, Kimitaka Nakazawa, Milos R Popovic, Kei Masani
Trunk instability is a major problem for individuals with thoracic and cervical spinal cord injury. Functional electrical stimulation (FES) neuroprosthesis, a technology that uses small electrical currents to artificially contract muscles, has previously been utilized to improve trunk stability during quasistatic and dynamic sitting. The aim of this study was to develop the first powered wheelchair-based neuroprosthesis and to test its feasibility for improving trunk stability. Eleven male, able-bodied individuals participated in the feasibility study...
July 14, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28713084/evalution-of-the-effectiveness-of-multimodal-approach-to-the-management-of-cervical-vertigo
#16
Olexandr A Jaroshevskyi, Oleksandr S Payenok, Anna V Logvinenko
INTRODUCTION: Vertigo is one of the most common complaints among patients consulting neurologists and general practitioners - family medicine. A special form of dizziness is cervical vertigo. However, the presence of chronic vertigo and imbalance in this group of patients makes it possible to include the treatment of vestibular rehabilitation in the program. AIM: Evalution of the effectiveness of multimodal approach to the management of cervical vertigo. MATERIAL AND METHODS: 109 patients aged from 18 to 45 with vertigo together with myofascial pain syndrome of neck and shoulder area were examined...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28698541/ataxia-telangiectasia-in-siblings-oral-motor-and-swallowing-characterization
#17
Silmara Rondon-Melo, Isabel Junqueira de Almeida, Claudia Regina Furquim de Andrade, Fernanda Chiarion Sassi, Daniela Regina Molini-Avejonas
BACKGROUND The body of literature on oral motor and swallowing disorders in patients with ataxia telangiectasia (AT) is limited. CASE REPORT The purpose of this study was to characterize oral motor and swallowing disorders in two siblings with AT, based on oral motor and swallowing assessments. Specific procedures were applied for oral motor and swallowing assessments and both patients underwent videofluoroscopy (VFS). Case 1 presented vocal instability, change in postural control during feeding; food retention in oral cavity; slower oral transit time; and multiple swallowing (signs for solid and liquid)...
July 12, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28694602/pseudarthrosis-due-to-galvanic-corrosion-presenting-as-subarachnoid-hemorrhage
#18
Rosemary Noel Beavers, Rishi Rajiv Lall, Juan Ortega Barnett, Sohum Kiran Desai
Two unlike metals near one another can break down as they move toward electrochemical equilibrium resulting in galvanic corrosion. We describe a case of electrochemical corrosion resulting in pseudarthrosis, followed by instrumentation failure leading to subarachnoid hemorrhage. A 53-year-old female with a history of cervical instability and two separate prior cervical fusion surgery with sublaminar cables presented with new onset severe neck pain. Restricted range of motion in her neck and bilateral Hoffman's was noted...
April 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/28692625/a-new-craniothoracic-mattress-for-immobilization-of-the-cervical-spine-in-critical-care-patients
#19
Micha Holla, Mitchel Driessen, Thomas G E Eggen, Robin A Daanen, Allard J F Hosman, Nico Verdonschot, Gerjon Hannink
Current immobilization techniques of the cervical spine are associated with complications including pressure ulcers, discomfort, and elevated intracranial pressures with limited access to the thorax and airway. In this study, a newly developed craniothoracic immobilizer (Pharaoh mattress) for critical care patients with cervical injury was tested for its restriction of cervical movement, peak interface pressures, comfort, and radiolucency, and compared with headblocks strapped to a spineboard. Cervical movement was measured by roentgen stereophotogrammetric analysis in 5 fresh frozen cadavers...
July 2017: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/28648003/-curative-effect-analysis-of-15-cases-of-cervical-intra-and-extra-spinal-tumors-by-microsurgical-resection
#20
Y Han, X L Zheng, L Li, Z Q Jiang, F Y Lou, S J Zhang
Objective: To explore the curative effect of microsurgical treatment of cervical intra- and extra-spinal tumors. Methods: The clinical data of 15 patients with cervical intra-and extra-spinal tumors in Department of Neurosurgery, the First Affiliated Hospital of Bengbu Medical College from January 2013 to February 2017 were retrospectively analyzed. According to Shaw's tumor stage: 6 cases in stage Ⅰ, 5 cases in stage Ⅱ, 3 cases in stage Ⅲ, and 1 case in stage Ⅳ. About the surgical methods: 9 cases were treated via posterior median semi-laminectomy approach, of which were internal fixation in 2 cases, and via posterior median approach spinous process and vertebral plate complex orthotopic replantation to spinal canal plasty in 3 cases, other 3 cases were operated via anterior cervical approach, including internal fixation in 1 case...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
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