Charlotte Johanna Laura Molenaar, Enrico Maria Minnella, Miquel Coca-Martinez, David Wouter Gerard Ten Cate, Marta Regis, Rashami Awasthi, Graciela Martínez-Palli, Manuel López-Baamonde, Raquel Sebio-Garcia, Carlo Vittorio Feo, Stefanus Johannes van Rooijen, Jennifer Marijke Janneke Schreinemakers, Rasmus Dahlin Bojesen, Ismail Gögenur, Edwin R van den Heuvel, Francesco Carli, Gerrit Dirk Slooter
IMPORTANCE: Colorectal surgery is associated with substantial morbidity rates and a lowered functional capacity. Optimization of the patient's condition in the weeks prior to surgery may attenuate these unfavorable sequelae. OBJECTIVE: To determine whether multimodal prehabilitation before colorectal cancer surgery can reduce postoperative complications and enhance functional recovery. DESIGN, SETTING, AND PARTICIPANTS: The PREHAB randomized clinical trial was an international, multicenter trial conducted in teaching hospitals with implemented enhanced recovery after surgery programs...
June 1, 2023: JAMA Surgery