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https://www.readbyqxmd.com/read/29092804/bilateral-vestibular-hypofunction-in-quantitative-head-impulse-test-clinical-characteristics-in-23-patients
#1
Hilla Levo, Heikki Aalto, Timo P Hirvonen
OBJECTIVE: To explore clinical features of patients with bilateral vestibular hypofunction (BVH) verified in motorized head impulse test (MHIT). MATERIALS AND METHODS: We examined clinical records of 23 adult patients (10 males and 13 females), whose gain of the vestibulo-ocular reflex in the MHIT was bilaterally lowered. Fifteen of 62 unilateral cochlear implant (CI) recipients routinely tested both pre- and postoperatively with the MHIT had BVH. Eight of 198 vestibular outpatients selected to the MHIT due to clinical causes had BVH...
November 2, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29075933/the-dynamics-of-neural-fields-on-bounded-domains-an-interface-approach-for-dirichlet-boundary-conditions
#2
Aytül Gökçe, Daniele Avitabile, Stephen Coombes
Continuum neural field equations model the large-scale spatio-temporal dynamics of interacting neurons on a cortical surface. They have been extensively studied, both analytically and numerically, on bounded as well as unbounded domains. Neural field models do not require the specification of boundary conditions. Relatively little attention has been paid to the imposition of neural activity on the boundary, or to its role in inducing patterned states. Here we redress this imbalance by studying neural field models of Amari type (posed on one- and two-dimensional bounded domains) with Dirichlet boundary conditions...
October 26, 2017: Journal of Mathematical Neuroscience
https://www.readbyqxmd.com/read/29055686/the-role-of-explorative-tympanotomy-in-patients-with-sudden-sensorineural-hearing-loss-with-and-without-perilymphatic-fistula
#3
REVIEW
N K Prenzler, B Schwab, D M Kaplan, S El-Saied
PURPOSE: The purpose of this study was to describe the role of explorative tympanotomy in patients with Profound Sudden Sensorineural Hearing Loss (SSNHL) without clinical evidence of perilymphatic or labyrinthine fistula and to compare intraoperative findings with the postoperative hearing outcome. STUDY DESIGN: Retrospective study of all patients diagnosed with SSNHL who underwent explorative tympanotomy between 2002 and 2005. SETTINGS: Tertiary care university-affiliated hospital...
October 9, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28986167/nonlocal-grazing-in-patterned-ecosystems
#4
E Siero
Many ecosystems exhibit gapped, labyrinthine, striped or spotted patterns. Important examples are vegetation patterns in drylands: these patterns are viewed as precursors of a catastrophic transition to a degraded state. A possible source of degradation is overgrazing, but many current spatially extended models include grazing in a local linear way. In this article nonlocal grazing responses are derived, taking into account (1) how many consumers there are (demographic response) (2) where they are (aggregative response) and (3) how much they forage (functional response)...
January 7, 2018: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28977031/sudden-sensorineural-hearing-loss-associated-with-inner-ear-lesions-detected-by-magnetic-resonance-imaging
#5
Jiwon Cho, Hanjae Cheon, Jung Hye Park, Hyo-Jeong Lee, Hyung-Jong Kim, Hyo Geun Choi, Ja-Won Koo, Sung Kwang Hong
Although recent advances in magnetic resonance imaging (MRI) techniques have contributed to the detection of tiny lesions in the internal auditory canal (IAC) that may be responsible for sudden sensorineural hearing loss (SSNHL), there have been relatively few studies on the clinical characteristics of intra-labyrinthine hemorrhage (ILH) and labyrinthitis versus those regarding IAC tumors. Our purpose was to investigate the frequency of those IAC lesions on MRI and their clinical characteristics. Initial MRIs of 200 patients with SSNHL (93 men, 107 women; mean age = 48...
2017: PloS One
https://www.readbyqxmd.com/read/28966150/benchmarking-distance-control-and-virtual-drilling-for-lateral-skull-base-surgery
#6
Eduard H J Voormolen, Sander Diederen, Marijn van Stralen, Peter A Woerdeman, Herke Jan Noordmans, Max A Viergever, Luca Regli, Pierre A Robe, Jan Willem Berkelbach van der Sprenkel
BACKGROUND: Novel audiovisual feedback methods were developed to improve image guidance during skull base surgery by providing audiovisual warnings when the drill tip enters a protective perimeter set at a distance around anatomic structures ("distance control") and visualizing bone drilling ("virtual drilling"). OBJECTIVE: To benchmark the drill damage risk reduction provided by distance control, to quantify the accuracy of virtual drilling, and to investigate whether the proposed feedback methods are clinically feasible...
September 29, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28951912/experimental-and-theoretical-studies-on-the-morphogenesis-of-bacterial-biofilms
#7
Cheng Zhang, Bo Li, Jing-Ying Tang, Xiao-Ling Wang, Zhao Qin, Xi-Qiao Feng
Biofilm morphogenesis not only reflects the physiological state of bacteria but also serves as a strategy to sustain bacterial survival. In this paper, we take the Bacillus subtilis colony as a model system to explore the morphomechanics of growing biofilms confined in a defined geometry. We find that the growth-induced stresses may drive the occurrence of both surface wrinkling and interface delamination in the biofilm, leading to the formation of a labyrinthine network on its surface. The wrinkles are perpendicular to the boundary of the constraint region...
October 18, 2017: Soft Matter
https://www.readbyqxmd.com/read/28947096/3d-constructive-interference-into-steady-state-3d-ciss-labyrinth-signal-alteration-in-patients-with-vestibular-schwannoma
#8
Franca Wagner, Evelyn Herrmann, Roland Wiest, Andreas Raabe, Corrado Bernasconi, Marco Caversaccio, Dominique Vibert
OBJECTIVE: To evaluate signal intensity of the inner ear using 3D-CISS imaging and correlated signal characteristics in patients with vestibular schwannoma to neuro-otological symptoms. METHODS: Sixty patients with unilateral vestibular schwannoma were retrospectively reviewed. All patients had had initial and follow-up magnetic resonance imaging (MRI). Individual treatment strategies consisted of "wait-and-watch", surgical tumour resection, stereotactic radiosurgery or both surgery and stereotactic radiosurgery...
September 22, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28929059/incidence-of-facial-nerve-canal-dehiscence-in-primary-and-revision-cholesteatoma-surgery
#9
Mohammad Faramarzi, Sareh Roosta
The aim of this retrospective study was to determine the incidence of facial canal dehiscence (FCD) in primary and revision cholesteatoma surgery in a tertiary referral center. Moreover, our second goal was to identify association between FCD and other intra-operative pathological findings in a group of patients with cholesteatoma surgery. Inclusion criteria were primary and revision canal wall up and canal wall down tympanomastoidectomy in patients who suffers from chronic otitis media (COM) with cholesteatoma...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28830539/endoscopically-assisted-transmastoid-approach-to-the-geniculate-ganglion-and-labyrinthine-facial-nerve
#10
Nicholas Jufas, Manohar Bance
BACKGROUND: Endoscopic transcanal approaches to the facial nerve allow excellent exposure of the tympanic facial nerve. This approach becomes limited when access is required to the more proximal geniculate ganglion and labyrinthine portion of the facial nerve. The aim of this report was to determine the feasibility of a transmastoid endoscopically assisted approach to the geniculate ganglion and labyrinthine facial nerve. This is an endoscopic cadaveric dissection and video review at a university anatomical laboratory...
August 22, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28826288/characteristic-mr-findings-suggesting-presumed-labyrinthine-hemorrhage
#11
Dong Sun Kim, Dong Woo Park, Tae Yoon Kim, Sangjoon Lee, Young Jun Lee, Ji Young Lee, Seung Hwan Lee, Jae Ho Chung
OBJECTIVES: To evaluate the magnetic resonance imaging (MRI) findings of labyrinthine hemorrhage as a cause of sudden sensorineural hearing loss (SSNHL). METHODS: MRI scans of 59 patients with SSNHL were retrospectively analyzed and compared to clinical features and audiometry data. MR images included pre-enhanced T1-weighted, 3D FLAIR volume isometric turbo spin-echo acquisition (VISTA), post-enhanced T1-weighted and 4-h-delayed enhanced FLAIR VISTA, and 3D thin-section proton density-weighted images...
December 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28819872/-hearing-restoration-with-cochlear-implants-after-translabyrinthine-vestibular-schwannoma-resection
#12
C Bohr, S Müller, J Hornung, U Hoppe, H Iro
BACKGROUND: Hearing restoration after translabyrinthine vestibular schwannoma resection is a challenge. Because the cochlea can begin to ossify a few months after cochlear or labyrinthine injury, the time interval for cochlear implant surgery is limited. To avoid complete ossification and to prolong the time interval until cochlear implantation, it is possible to insert a placeholder (depth gauge) into the cochlea and perform the cochlear implant surgery at a later time point (two-stage approach)...
September 2017: HNO
https://www.readbyqxmd.com/read/28803051/variations-in-the-labyrinthine-segment-of-facial-nerve-canal-revealed-by-high-resolution-computed-tomography
#13
Aiyan Jin, Peng Xu, Fengqin Qu
OBJECTIVE: To study variations in the labyrinthine segment of fallopian canal and the associated middle and inner ear malformations. METHOD: The high-resolution computed tomography (HRCT) images of the temporal bone in 24 patients with congenital variations in the labyrinthine segment of fallopian canal were analyzed retrospectively. The length of labyrinthine segment of the facial nerve and angle of the first genu of 10 normal subjects were also measured. Based on the original axial images, multi-planar reformation (MPR) and curved-planar reformation (CPR) images of bilateral ossicular chains, inner ear structure and fallopian canal were reconstructed...
August 9, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28799140/management-of-labyrinthine-fistula-hearing-preservation-versus-prevention-of-residual-disease
#14
S Geerse, M J F de Wolf, F A Ebbens, E van Spronsen
The objective of the study was to evaluate postoperative hearing and disease control after cholesteatoma surgery for labyrinthine fistulas. In a retrospective cohort study, we evaluated a consecutive cohort comprising 44 patients (45 ears) with labyrinthine fistulas associated with chronic otitis media with cholesteatoma who underwent surgery between 2002 and 2015. We looked at patient characteristics, pre- and postoperative bone conduction thresholds (BCT), operative approach and findings, extent of disease and the occurrence of residual disease...
August 10, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28724461/tuberculous-otitis-media-a-resurgence
#15
M Kameswaran, K Natarajan, M Parthiban, P V Krishnan, S Raghunandhan
OBJECTIVE: Tuberculosis is a global health problem that is especially prevalent in developing countries such as India. Recently, atypical presentation has become more common and a high index of suspicion is essential. This study analysed the various presenting symptoms and signs of tuberculous otitis media and the role of diagnostic tests, with the aim of formulating criteria for the diagnosis. METHODS: A total of 502 patients underwent tympanomastoidectomy over a two-year period...
September 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28718302/cardiovascular-risk-factors-among-patients-with-vestibular-neuritis
#16
Yahav Oron, Shay Shemesh, Sagit Shushan, Udi Cinamon, Abraham Goldfarb, Ron Dabby, Sharon Ovnat Tamir
OBJECTIVE: To investigate the correlation between cardiovascular risk factors (CVRFs) and vestibular neuritis (VN) in hospitalized adult patients. METHODS: A cross-sectional retrospective study was conducted in a tertiary hospital setting. The medical records of patients (aged over 18 years old) who were hospitalized between the years 2005 and 2014 with the diagnosis of VN were retrieved. Inclusion criteria were: (1) acute vertigo lasting for at least 24 hours, (2) absence of auditory complaints, (3) horizontal unidirectional nystagmus present during physical examination, and (4) absence of neurological symptoms or signs...
August 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28708792/can-preoperative-ct-scans-be-used-to-predict-facial-nerve-stimulation-following-ci
#17
Jonathan L Hatch, Habib G Rizk, Michael W Moore, Elizabeth E Camposeo, Shaun A Nguyen, Paul R Lambert, Ted A Meyer, Theodore R McRackan
OBJECTIVES: 1) To determine the ability of preoperative computed tomography (CT) to predict facial nerve stimulation (FNS) after cochlear implantation (CI). 2) To recognize the limitations of CT in predicting FNS. STUDY DESIGN: Patient control study. SETTING: Tertiary care academic medical center. SUBJECTS: Adult patients with CI from 2003 to 2015. METHODS: Patients with severe FNS (n = 4) were compared with randomly selected CI patients (n = 28)...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28696161/comparison-of-normal-facial-nerve-enhancement-at-3t-mri-using-gadobutrol-and-gadopentetate-dimeglumine
#18
Rupa Radhakrishnan, Shamima Ahmed, Joshua Cole Tilden, Humberto Morales
Background and purpose The facial nerve is unique among cranial nerves in demonstrating normal enhancement of particular segments. The effect of varying T1 relaxivities of gadolinium-based contrast agents on facial nerve enhancement is unclear. In this study, we assess differences in normal facial nerve enhancement with two different gadolinium-based contrast agents, gadobutrol and gadopentetate dimeglumine. In addition, we evaluate differences in facial nerve enhancement with spin-echo (SE) T1 versus 3D inversion recovery prepared fast spoiled gradient-echo (FSPGR) post-contrast sequences...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28676687/maternal-htra3-optimizes-placental-development-to-influence-offspring-birth-weight-and-subsequent-white-fat-gain-in-adulthood
#19
Ying Li, Lois A Salamonsen, Jonathan Hyett, Fabricio da Silva Costa, Guiying Nie
High temperature requirement factor A3 (HtrA3), a member of the HtrA protease family, is highly expressed in the developing placenta, including the maternal decidual cells in both mice and humans. In this study we deleted the HtrA3 gene in the mouse and crossed females carrying zero, one, or two HtrA3-expressing alleles with HtrA3(+/-) males to investigate the role of maternal vs fetal HtrA3 in placentation. Although HtrA3(-/-) mice were phenotypically normal and fertile, HtrA3 deletion in the mother resulted in intra-uterine growth restriction (IUGR)...
July 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28628917/anatomical-characteristics-of-facial-nerve-and-cochlea-interaction
#20
Nadine Schart-Morén, Sune Larsson, Helge Rask-Andersen, Hao Li
OBJECTIVE: The aim was to study the relationship between the labyrinthine portion (LP) of the facial canal and the cochlea in human inner ear molds and temporal bones using micro-CT and 3D rendering. A reduced cochlea-facial distance may spread electric currents from the cochlear implant to the LP and cause facial nerve stimulation. Influencing factors may be the topographic anatomy and otic capsule properties. METHODS: An archival collection of human temporal bones underwent micro-CT and 3D reconstruction...
2017: Audiology & Neuro-otology
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