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https://www.readbyqxmd.com/read/28929059/incidence-of-facial-nerve-canal-dehiscence-in-primary-and-revision-cholesteatoma-surgery
#1
Mohammad Faramarzi, Sareh Roosta
The aim of this retrospective study was to determine the incidence of facial canal dehiscence (FCD) in primary and revision cholesteatoma surgery in a tertiary referral center. Moreover, our second goal was to identify association between FCD and other intra-operative pathological findings in a group of patients with cholesteatoma surgery. Inclusion criteria were primary and revision canal wall up and canal wall down tympanomastoidectomy in patients who suffers from chronic otitis media (COM) with cholesteatoma...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28830539/endoscopically-assisted-transmastoid-approach-to-the-geniculate-ganglion-and-labyrinthine-facial-nerve
#2
Nicholas Jufas, Manohar Bance
BACKGROUND: Endoscopic transcanal approaches to the facial nerve allow excellent exposure of the tympanic facial nerve. This approach becomes limited when access is required to the more proximal geniculate ganglion and labyrinthine portion of the facial nerve. The aim of this report was to determine the feasibility of a transmastoid endoscopically assisted approach to the geniculate ganglion and labyrinthine facial nerve. This is an endoscopic cadaveric dissection and video review at a university anatomical laboratory...
August 22, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28826288/characteristic-mr-findings-suggesting-presumed-labyrinthine-hemorrhage
#3
Dong Sun Kim, Dong Woo Park, Tae Yoon Kim, Sang Joon Lee, Young-Jun Lee, Ji Young Lee, Seung Hwan Lee, Jae Ho Chung
OBJECTIVES: To evaluate the magnetic resonance imaging (MRI) findings of labyrinthine hemorrhage as a cause of sudden sensorineural hearing loss (SSNHL). METHODS: MRI scans of 59 patients with SSNHL were retrospectively analyzed and compared to clinical features and audiometry data. MR images included pre-enhanced T1-weighted, 3D FLAIR VISTA, post-enhanced T1-weighted and 4-h-delayed enhanced FLAIR volume isometric turbo spin-echo acquisition (VISTA), and 3D thin-section proton density-weighted images...
August 21, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28819872/-hearing-restoration-with-cochlear-implants-after-translabyrinthine-vestibular-schwannoma-resection
#4
C Bohr, S Müller, J Hornung, U Hoppe, H Iro
BACKGROUND: Hearing restoration after translabyrinthine vestibular schwannoma resection is a challenge. Because the cochlea can begin to ossify a few months after cochlear or labyrinthine injury, the time interval for cochlear implant surgery is limited. To avoid complete ossification and to prolong the time interval until cochlear implantation, it is possible to insert a placeholder (depth gauge) into the cochlea and perform the cochlear implant surgery at a later time point (two-stage approach)...
August 17, 2017: HNO
https://www.readbyqxmd.com/read/28803051/variations-in-the-labyrinthine-segment-of-facial-nerve-canal-revealed-by-high-resolution-computed-tomography
#5
Aiyan Jin, Peng Xu, Fengqin Qu
OBJECTIVE: To study variations in the labyrinthine segment of fallopian canal and the associated middle and inner ear malformations. METHOD: The high-resolution computed tomography (HRCT) images of the temporal bone in 24 patients with congenital variations in the labyrinthine segment of fallopian canal were analyzed retrospectively. The length of labyrinthine segment of the facial nerve and angle of the first genu of 10 normal subjects were also measured. Based on the original axial images, multi-planar reformation (MPR) and curved-planar reformation (CPR) images of bilateral ossicular chains, inner ear structure and fallopian canal were reconstructed...
August 9, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28799140/management-of-labyrinthine-fistula-hearing-preservation-versus-prevention-of-residual-disease
#6
S Geerse, M J F de Wolf, F A Ebbens, E van Spronsen
The objective of the study was to evaluate postoperative hearing and disease control after cholesteatoma surgery for labyrinthine fistulas. In a retrospective cohort study, we evaluated a consecutive cohort comprising 44 patients (45 ears) with labyrinthine fistulas associated with chronic otitis media with cholesteatoma who underwent surgery between 2002 and 2015. We looked at patient characteristics, pre- and postoperative bone conduction thresholds (BCT), operative approach and findings, extent of disease and the occurrence of residual disease...
August 10, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28724461/tuberculous-otitis-media-a-resurgence
#7
M Kameswaran, K Natarajan, M Parthiban, P V Krishnan, S Raghunandhan
OBJECTIVE: Tuberculosis is a global health problem that is especially prevalent in developing countries such as India. Recently, atypical presentation has become more common and a high index of suspicion is essential. This study analysed the various presenting symptoms and signs of tuberculous otitis media and the role of diagnostic tests, with the aim of formulating criteria for the diagnosis. METHODS: A total of 502 patients underwent tympanomastoidectomy over a two-year period...
September 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28718302/cardiovascular-risk-factors-among-patients-with-vestibular-neuritis
#8
Yahav Oron, Shay Shemesh, Sagit Shushan, Udi Cinamon, Abraham Goldfarb, Ron Dabby, Sharon Ovnat Tamir
OBJECTIVE: To investigate the correlation between cardiovascular risk factors (CVRFs) and vestibular neuritis (VN) in hospitalized adult patients. METHODS: A cross-sectional retrospective study was conducted in a tertiary hospital setting. The medical records of patients (aged over 18 years old) who were hospitalized between the years 2005 and 2014 with the diagnosis of VN were retrieved. Inclusion criteria were: (1) acute vertigo lasting for at least 24 hours, (2) absence of auditory complaints, (3) horizontal unidirectional nystagmus present during physical examination, and (4) absence of neurological symptoms or signs...
August 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28708792/can-preoperative-ct-scans-be-used-to-predict-facial-nerve-stimulation-following-ci
#9
Jonathan L Hatch, Habib G Rizk, Michael W Moore, Elizabeth E Camposeo, Shaun A Nguyen, Paul R Lambert, Ted A Meyer, Theodore R McRackan
OBJECTIVES: 1) To determine the ability of preoperative computed tomography (CT) to predict facial nerve stimulation (FNS) after cochlear implantation (CI). 2) To recognize the limitations of CT in predicting FNS. STUDY DESIGN: Patient control study. SETTING: Tertiary care academic medical center. SUBJECTS: Adult patients with CI from 2003 to 2015. METHODS: Patients with severe FNS (n = 4) were compared with randomly selected CI patients (n = 28)...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28696161/comparison-of-normal-facial-nerve-enhancement-at-3t-mri-using-gadobutrol-and-gadopentetate-dimeglumine
#10
Rupa Radhakrishnan, Shamima Ahmed, Joshua Cole Tilden, Humberto Morales
Background and purpose The facial nerve is unique among cranial nerves in demonstrating normal enhancement of particular segments. The effect of varying T1 relaxivities of gadolinium-based contrast agents on facial nerve enhancement is unclear. In this study, we assess differences in normal facial nerve enhancement with two different gadolinium-based contrast agents, gadobutrol and gadopentetate dimeglumine. In addition, we evaluate differences in facial nerve enhancement with spin-echo (SE) T1 versus 3D inversion recovery prepared fast spoiled gradient-echo (FSPGR) post-contrast sequences...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28676687/maternal-htra3-optimizes-placental-development-to-influence-offspring-birth-weight-and-subsequent-white-fat-gain-in-adulthood
#11
Ying Li, Lois A Salamonsen, Jonathan Hyett, Fabricio da Silva Costa, Guiying Nie
High temperature requirement factor A3 (HtrA3), a member of the HtrA protease family, is highly expressed in the developing placenta, including the maternal decidual cells in both mice and humans. In this study we deleted the HtrA3 gene in the mouse and crossed females carrying zero, one, or two HtrA3-expressing alleles with HtrA3(+/-) males to investigate the role of maternal vs fetal HtrA3 in placentation. Although HtrA3(-/-) mice were phenotypically normal and fertile, HtrA3 deletion in the mother resulted in intra-uterine growth restriction (IUGR)...
July 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28628917/anatomical-characteristics-of-facial-nerve-and-cochlea-interaction
#12
Nadine Schart-Morén, Sune Larsson, Helge Rask-Andersen, Hao Li
OBJECTIVE: The aim was to study the relationship between the labyrinthine portion (LP) of the facial canal and the cochlea in human inner ear molds and temporal bones using micro-CT and 3D rendering. A reduced cochlea-facial distance may spread electric currents from the cochlear implant to the LP and cause facial nerve stimulation. Influencing factors may be the topographic anatomy and otic capsule properties. METHODS: An archival collection of human temporal bones underwent micro-CT and 3D reconstruction...
2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28623973/dynamic-maternal-and-fetal-notch-activity-and-expression-in-placentation
#13
Heather I Levin, Chantae S Sullivan-Pyke, Virginia E Papaioannou, Ronald J Wapner, Jan K Kitajewski, Carrie J Shawber, Nataki C Douglas
INTRODUCTION: Murine placentation requires trophoblast Notch2, while the Notch ligand, JAGGED1, is reduced in invasive trophoblasts from women with preeclampsia. However, the placental cells with active Notch signaling and expression of other Notch proteins and ligands in placentation have yet to be defined. We sought to identify endothelial cell and trophoblast subtypes with canonical Notch signaling in the decidua and placenta and correlate this to expression of Notch proteins and ligands...
July 2017: Placenta
https://www.readbyqxmd.com/read/28623972/placentation-in-the-colugos-cynocephalus-volans-and-galeopterus-variegatus-dermoptera-and-the-transition-from-labyrinthine-to-villous-placentation-in-primates
#14
A M Carter, A M Mess
INTRODUCTION: Phylogenetics and genomics place colugos as the sister group to primates. Therefore their placentation is of interest in an evolutionary perspective. Previous accounts are fragmentary, not readily accessible and sometimes contradictory. METHODS: We have examined archival material covering the early development of fetal membranes and placenta, the fate of the yolk sac and definitive placentation. RESULTS: Initially the trophoblast extended over a rather broad but shallow area, enclosing maternal blood spaces...
July 2017: Placenta
https://www.readbyqxmd.com/read/28607891/cholesteatoma-induced-labyrinthine-fistula-is-aggressiveness-in-removing-disease-justified
#15
Prem Sagar, K Devaraja, Rajeev Kumar, Sumanth Bolu, Suresh C Sharma
Issues of complete disease clearance and hearing preservation in cholesteatoma induced labyrinthine fistula cases has been discussed and updated in this article. Successful disease clearance and hearing preservation in a case of cholesteatoma induced isolated cochlear promontory fistula encouraged us to retrospectively analyse 13 more cases of cholesteatoma induced labyrinthine fistula who presented in emergency service as complicated chronic suppurtive otitis media. Pre-operatively nine patients experienced vertigo, two had profound sensori neural hearing loss and radiology was suggestive of labyrinthine fistula in 12 patients...
June 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28573817/imaging-of-labyrinthine-fistula-after-repair-with-bone-pate
#16
Jeffrey T Vrabec
OBJECTIVES/HYPOTHESIS: To demonstrate imaging of labyrinthine fistula due to cholesteatoma and illustrate outcome following repair with bone pate. STUDY DESIGN: Retrospective review. METHODS: Patients with labyrinthine fistula due to cholesteatoma were identified, and pre- and postoperative imaging was assessed. Method of repair was recorded. The fistula site was examined for patency and bone density after repair. RESULTS: Twenty-nine fistulae were seen in a cohort of 375 cholesteatoma cases (8%)...
June 2, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28570419/ultra-high-field-9-4-t-mri-analysis-of-contrast-agent-transport-across-the-blood-perilymph-barrier-and-intrastrial-fluid-blood-barrier-in-the-mouse-inner-ear
#17
S Allen Counter, Sahar Nikkhou-Aski, Peter Damberg, Cecilia Engmér Berglin, Göran Laurell
HYPOTHESIS: Effective paramagnetic contrast agent for the penetration of the perilymphatic spaces of the scala tympani, scala vestibuli, and scala media of the mouse inner ear can be determined using intravenous injection of various gadolinium (Gd) complexes and ultra-high-field magnetic resonance imaging (MRI) at 9.4 Tesla. BACKGROUND: A number of contrast agents have been explored in experimental high-field MRI to determine the most effective Gd complex for ideal signal-to-noise ratio and maximal visualization of the in vivo mammalian inner ear in analyzing the temporal and spatial parameters involved in drug penetration of the blood-perilymph barrier and intrastrial fluid-blood barrier in the mouse model using MRI...
August 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28532527/how-i-do-it-underwater-endoscopic-ear-surgery-for-plugging-in-superior-canal-dehiscence-syndrome
#18
D Yamauchi, Y Hara, H Hidaka, T Kawase, Y Katori
BACKGROUND: Underwater endoscopic ear surgery does not require suction and so protects the inner ear from unexpected aeration that may damage its function in the treatment of labyrinthine fistula. A method of underwater endoscopic ear surgery is proposed for the treatment of superior canal dehiscence. METHODS: Underwater endoscopic ear surgery was performed for plugging of the superior semicircular canal through the transmastoid approach. Saline solution was infused into the mastoid cavity through an Endo-Scrub Lens Cleaning Sheath...
August 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28523740/new-data-about-semicircular-canal-morphology-and-locomotion-in-modern-hominoids
#19
Anne Le Maître, Philipp Schuetz, Patrick Vignaud, Michel Brunet
The labyrinth has two functional parts: the cochlea for audition and the vestibular system for equilibrioception. In the latter, the semicircular ducts and the otolithic organs are sensitive to rotational and linear accelerations of the head, respectively. The labyrinthine morphology influences perception accuracy, hence the adaptation to a specific locomotor pattern. The aim of this study is to determine the relationship between locomotion and semicircular canal morphology using geometric morphometrics, and to explain these links with existing functional models...
May 19, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28523122/sex-differences-in-rat-placental-development-from-pre-implantation-to-late-gestation
#20
J I Kalisch-Smith, D G Simmons, M Pantaleon, K M Moritz
BACKGROUND: A male fetus is suggested to be more susceptible to in utero and birth complications. This may be due in part to altered morphology or function of the XY placenta. We hypothesised that sexual dimorphism begins at the blastocyst stage with sex differences in the progenitor trophectoderm (TE) and its derived trophoblast lineages, as these cells populate the majority of cell types within the placenta. We investigated sex-specific differences in cell allocation in the pre-implantation embryo and further characterised growth and gene expression of the placental compartments from the early stages of the definitive placenta through to late gestation...
2017: Biology of Sex Differences
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