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https://www.readbyqxmd.com/read/28188328/neurons-in-the-pontomedullary-reticular-formation-receive-converging-inputs-from-the-hindlimb-and-labyrinth
#1
Derek M Miller, William M DeMayo, George H Bourdages, Samuel R Wittman, Bill J Yates, Andrew A McCall
The integration of inputs from vestibular and proprioceptive sensors within the central nervous system is critical to postural regulation. We recently demonstrated in both decerebrate and conscious cats that labyrinthine and hindlimb inputs converge onto vestibular nucleus neurons. The pontomedullary reticular formation (pmRF) also plays a key role in postural control, and additionally participates in regulating locomotion. Thus, we hypothesized that like vestibular nucleus neurons, pmRF neurons integrate inputs from the limb and labyrinth...
February 10, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28124632/external-auditory-canal-meningioma-imaging-features-in-a-series-of-three-cases
#2
J Dixon, I Zammit-Maempel, J Hill
BACKGROUND: Direct extension of an intracranial meningioma to involve the temporal bone is rare. Recognised sites of origin and routes of access to the middle ear and labyrinthine apparatus have been described. Direct spread through the temporal bone to primarily involve the external auditory canal has not been widely reported in the literature. CASE REPORTS: This paper discusses clinical and radiological findings in three cases of temporal bone meningioma presenting as masses within the external auditory canal...
January 26, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28095733/decoding-crucial-lncrnas-implicated-in-neurogenesis-and-neurological-disorders
#3
R Ayana, Shailja Singh, Soumya Pati
Unraveling transcriptional heterogeneity and the labyrinthine nature of neurodevelopment can probe insights into neuropsychiatric disorders. It is noteworthy that adult neurogenesis is restricted to the Sub Ventricular and Sub Granular zones (SVZ/SGZ) of the brain. Recent studies suggest long non-coding RNAs (lncRNAs) as an avant-garde class of regulators implicated in neurodevelopment. But, paucity exists in the knowledge regarding lncRNAs in neurogenesis and their associations with neurodevelopmental defects...
January 17, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/28071070/surgery-for-cholesteatomatous-labyrinthine-fistula
#4
John Lim, Anupriya Gangal, Michael Brian Gluth
OBJECTIVE: There is uncertainty regarding the ideal surgical management of cholesteatomatous labyrinthine fistulae. The objective was to review the published evidence to determine whether a difference exists in hearing outcome for cholesteatoma matrix removal or matrix exteriorization. DATA SOURCES: Systematic MEDLINE and Web of Science searches identified publications describing hearing results after cholesteatoma matrix removal or matrix exteriorization. REVIEW METHODS: Three reviewers appraised the studies for quality, level of evidence, and extracted data...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28069982/clinical-reasoning-labyrinthine-hemorrhage-an-unusual-etiology-for-peripheral-vertigo
#5
Simy K Parikh, Samuel A Frank
No abstract text is available yet for this article.
January 10, 2017: Neurology
https://www.readbyqxmd.com/read/28030893/recent-advances-in-understanding-audiovestibular-loss-of-a-vascular-cause
#6
REVIEW
Hyun-Ah Kim, Hyung Lee
Acute audiovestibular loss is characterized by abrupt onset of prolonged (lasting days) vertigo and hearing loss. Acute ischemic stroke in the distribution of the anterior inferior cerebellar artery (AICA) is known to be the leading cause of acute audiovestibular loss. So far, eight subgroups of AICA territory infarction have been identified according to the patterns of audiovestibular dysfunctions, among which the most common pattern is the combined loss of auditory and vestibular functions. Unlike inner ear dysfunction of a viral cause, which can commonly present as an isolated vestibular (i...
January 2017: Journal of Stroke
https://www.readbyqxmd.com/read/28027080/carcinoid-like-labyrinthine-pattern-in-sebaceous-neoplasms-represents-a-sebaceous-mantle-phenotype-immunohistochemical-analysis-of-aberrant-vimentin-expression-and-cytokeratin-20-positive-merkel-cell-distribution
#7
Keisuke Goto, Takashi Anan, Takaya Fukumoto, Tetsunori Kimura, Noriyuki Misago
This study investigated the nature of carcinoid-like, labyrinthine, rippled, and conventional cell arrangements in sebaceous neoplasms, focusing on vimentin expression and Merkel cell distribution in sebaceous neoplasms relative to these findings in normal sebaceous units and other sebaceous conditions. Immunohistochemistry for vimentin and cytokeratin 20 (CK20) was evaluated in carcinoid-like (n = 2), labyrinthine (n = 4), rippled (n = 3), and conventional (n = 6) sebaceomas; sebaceous mantle hyperplasia (n = 1); steatocystomas (n = 5); fibrofolliculomas (n = 4); sebaceous mantleoma (n = 1); sebaceous gland hyperplasias (n = 4); sebaceous adenomas (n = 4); and sebaceous carcinomas (n = 4) as well as normal skin tissue...
December 23, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28017492/superior-canal-dehiscence-with-tegmen-defect-revealed-by-otoscopy-video-clip-demonstration-of-pulsatile-tympanic-membrane
#8
Andrea Castellucci, Cristina Brandolini, Gianluca Piras, Ignacio Javier Fernandez, Davide Giordano, Carmine Pernice, Giovanni Carlo Modugno, Antonio Pirodda, Gian Gaetano Ferri
Superior canal dehiscence is a pathologic condition of the otic capsule acting as aberrant window of the inner ear. It results in reduction of inner ear impedance and in abnormal exposure of the labyrinthine neuroepithelium to the action of the surrounding structures. The sum of these phenomena leads to the onset of typical cochleo-vestibular symptoms and signs. Among them, pulsatile tinnitus has been attributed to a direct transmission of intracranial vascular activities to labyrinthine fluids. We present the first video-otoscopic documentation of spontaneous pulse-synchronous movements of the tympanic membrane in two patients with superior canal dehiscence...
December 22, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27999985/mri-of-endolymphatic-hydrops-in-patients-with-meniere-s-disease-a-case-controlled-study-with-a-simplified-classification-based-on-saccular-morphology
#9
Arnaud Attyé, Michael Eliezer, Naïla Boudiaf, Irène Tropres, David Chechin, Sébastien Schmerber, Georges Dumas, Alexandre Krainik
OBJECTIVES: Endolymphatic hydrops (EH) can be studied in patients by MRI. With the semi-quantitative grading system, previous imaging studies showed discrepancies in the occurrence and grading of EH in patients with Meniere's disease (MD). Here, we compared the inversion of the saccule to utricle area ratio (SURI) with the semi-quantitative method of grading conventionally used to diagnose MD. METHODS: Imaging was carried out on a 3-T MRI scanner. We performed 3D-FLAIR sequences 4 h after a single intravenous dose of contrast agent...
December 20, 2016: European Radiology
https://www.readbyqxmd.com/read/27989483/clinical-study-of-seven-patients-with-infarction-in-territories-of-the-anterior-inferior-cerebellar-artery
#10
Katsuhiko Ogawa, Yutaka Suzuki, Keiko Takahashi, Takayoshi Akimoto, Satoshi Kamei, Masayoshi Soma
BACKGROUND: The prominent features of anterior inferior cerebellar artery (AICA) infarction are vertigo, cerebellar ataxia, and impaired hearing. The present study investigated neurological characteristics associated with AICA infarction. MATERIALS AND METHODS: The locations of infarcts in 7 patients (age, 32-72 years) with AICA infarction were divided into the lower lateral pons, the middle cerebellar peduncle (MCP), and the cerebellum. RESULTS: Ischemic lesions were located in the MCP in 6 patients, spread to the lower lateral pons in 3, and involved the cerebellum in 4 patients...
December 15, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/27981350/the-role-of-bone-resorption-in-the-etiopathogenesis-of-acquired-middle-ear-cholesteatoma
#11
REVIEW
Shumin Xie, Xiaoli Wang, Jihao Ren, Wei Liu
Cholesteatoma is a destructive squamous epithelial lesion of the temporal bone which gradually expands and leads to serious complications by destruction of nearby bony structures. Erosion caused by bone resorption of the ossicular chain and bony labyrinth may result in hearing loss, vestibular dysfunction, facial paralysis, labyrinthine fistulae and intracranial complications. The exact underlying cellular and molecular mechanism of bone resorption in acquired cholesteatoma still remains unexplained. Pubmed database and China National Knowledge Infrastructure were screened for articles focusing on bone resorption in acquired cholesteatoma...
December 16, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27934541/association-between-endothelial-dysfunction-and-otoneurological-symptoms-in-children-with-sickle-cell-disease
#12
Mara Renata Rissatto-Lago, Cristina Salles, Fernando Gesteira Campos de Pinho, Isa Menezes Lyra, Regina Terse-Ramos, Rozana Teixeira, Ana Marice Ladeia
OBJECTIVE: To evaluate the association between endothelial dysfunction and otoneurological symptoms and vaso-occlusive phenomena in children with sickle cell disease (SCD). METHODS: Cross-sectional study with 54 children, aged between 6 and19 years of age, of whom 28 had genotype SS and 26 apparently healthy (AA genotype) whose parents or guardians, or the children themselves, filled out a questionnaire designed to assess their otoneurological symptoms. All the individuals were submitted assessment of endothelial function by flow-mediated dilation (FMD) percentage with reactive hyperemia of brachial artery Doppler...
December 9, 2016: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/27897128/defining-the-limits-of-endoscopic-access-to-internal-auditory-canal
#13
Adam Master, Mickie Hamiter, Maura Cosetti
OBJECTIVE: To quantify surgical access to the internal auditory canal (IAC) using an exclusively endoscopic transcanal approach (EETA) and investigate surgically relevant relationships with neurovascular and osseous landmarks of the temporal bone. MATERIALS AND METHODS: Anatomical dissection of two paired temporal bones and 15 unpaired temporal bones was performed using an exclusively endoscopic approach to IAC. The dissection proceeded until the cerebellopontine angle (CPA) could be accessed...
November 28, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27881133/alcohol-and-stroke-the-splitters-win-again
#14
EDITORIAL
Arthur L Klatsky, H Nicole Tran
Study of the relationships of alcohol drinking and risk of stroke can readily become mired in the labyrinthine interactions of drinking categorizations, non-linear associations, disparate cardiovascular conditions, and the heterogeneous types of stroke. This Commentary discusses the recent article by Larsson et al. (BMC Medicine 14:178, 2016). The authors split their material into separate meta-analyses of subarachnoid hemorrhage, intracerebral hemorrhage, and ischemic stroke, finding disparate alcohol-stroke relationships...
November 24, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27836252/clinicopathological-study-of-47-cases-of-sebaceoma
#15
F Bourlond, C Velter, B Cribier
BACKGROUND: Sebaceoma is a rare and poorly understood form of sebaceous tumour, and it is of great significance since it may reveal Muir-Torre syndrome (MTS). Herein, we present a series of cases with details of the histopathological appearance. PATIENTS AND METHODS: We examined records of cases labelled as sebaceous tumour recorded at the Strasbourg Dermatopathology Laboratory between 1991 and 2015. We include cases of benign sebaceous tumour predominantly involving immature basophilic cells...
December 2016: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27821232/-clinicopathologic-study-of-seromucinous-carcinoma-of-ovary
#16
S X Tang, Y H Sun, Y Xu, X R Zhou, W T Yang
Objective: To elucidate the clinicopathologic characteristics, immunophenotype and differential diagnosis of ovarian seromucinous carcinoma. Methods: The clinical and pathological characteristics of 7 cases of ovarian seromucinous carcinoma were analyzed. Immunohistochemical study of selected markers was performed employing the EnVision method. Literature of ovarian seromucinous carcinoma were also reviewed. Results: The age of the 7 ovarian seromucinous carcinoma patients ranged from 27 to 70 years of age (mean=48 years)...
November 8, 2016: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/27784476/-effects-of-prenatal-maternal-seizure-on-hippocampal-damage-and-cognitive-deficits-in-offspring-rats
#17
Y Lu, W P Wang, X X Wang, J J Feng, Z P Guo, L M Liu, T Xie, R R Zhao, Y L Cai
Objective: To observe hippocampal damage and cognitive impairment of offspring exposed to prenatal maternal seizure induced by amygdala kindling, and to explore the underlying mechanism by the detection of pathological changes of placenta. Method: Adult female SD rats were randomly divided into three groups: control group(8 rats), kindling group(12 rats) and sham group(8 rats). All the rats were allowed to mate after one week's fully kindling. The pregnant rats in kindling group received electric stimulation every 48 h...
October 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27765098/-ct-study-on-the-development-of-facial-nerve-canal-in-children
#18
J M Li, W B Xu, J W Zhong, H Y Wu, W C Dai
Objective: To assess the characteristics of facial nerve canal between normal anatomy and dysplasia of children in different ages. Methods: A total of 492 health ears were divided into six groups, neonatal group (<1 m , n=42), infancy group(1 m-1 y, n=106), toddler group(1-3 y, n=102), preschool group (3-6 y, n=100), school group(6-10 y, n=60)and adolescent group (10-14 y, n=82). The length and diameter of facial nerve canal and that angles of first and second genu were measured with CT in each group. Results: ①The lengths of facial nerve canal in neonatal and infancy group were shorter than other four groups, especially in the mastoid segments of facial nerve canal...
October 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/27746123/subjective-visual-vertical-after-treatment-of-benign-paroxysmal-positional-vertigo
#19
Maristela Mian Ferreira, Maurício Malavasi Ganança, Heloisa Helena Caovilla
INTRODUCTION: Otolith function can be studied by testing the subjective visual vertical, because the tilt of the vertical line beyond the normal range is a sign of vestibular dysfunction. Benign paroxysmal positional vertigo is a disorder of one or more labyrinthine semicircular canals caused by fractions of otoliths derived from the utricular macula. OBJECTIVE: To compare the subjective visual vertical with the bucket test before and immediately after the particle repositioning maneuver in patients with benign paroxysmal positional vertigo...
September 28, 2016: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/27739592/risk-of-progressive-hearing-loss-in-untreated-superior-semicircular-canal-dehiscence
#20
Neil S Patel, Jacob B Hunter, Brendan P O'Connell, Natalie M Bertrand, George B Wanna, Matthew L Carlson
OBJECTIVE: Patients with incidental or minimally symptomatic superior semicircular canal dehiscence (SSCD) are usually observed, without surgical repair. However, it remains unknown whether a labyrinthine fistula of the superior semicircular canal is associated with progressive conductive or sensorineural hearing loss over time. STUDY DESIGN: Retrospective review at two tertiary care academic referral centers. METHODS: Adults analyzed were diagnosed with SSCD by high-resolution temporal bone computed tomography and vestibular evoked myogenic potential testing and observed with a minimum of two sequential audiograms...
October 14, 2016: Laryngoscope
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