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https://www.readbyqxmd.com/read/29590734/a-comparative-study-of-data-collection-methods-in-the-process-of-nursing-detection-of-chemotherapy-side-effects-using-a-self-reporting-questionnaire
#1
Marco Di Muzio, Alessandra Marinucci, Anna De Benedictis, Daniela Tartaglini
Ocular vestibular evoked myogenic potentials (oVEMP) and cervical VEMP (cVEMP) are newer diagnostic methods, which allow an insight into the otolith senses. Our aim was to determine changes in certain parameters of the VEMP wave complex after successfully performed repositioning procedure, as an indicator of the state of recovery in patients with benign paroxysmal positional vertigo (BPPV). This may confirm the theory of otolith returning into the area of otolithic senses. The study included 48 patients with unilateral posterior semicircular canal BPPV...
December 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29590733/role-of-vestibular-evoked-myogenic-potentials-as-an-indicator-of-recovery-in-patients-with-benign-paroxysmal-positional-vertigo
#2
Tihana Mendeš, Siniša Maslovara, Andrijana Včeva, Silva Butković Soldo
Ocular vestibular evoked myogenic potentials (oVEMP) and cervical VEMP (cVEMP) are newer diagnostic methods, which allow an insight into the otolith senses. Our aim was to determine changes in certain parameters of the VEMP wave complex after successfully performed repositioning procedure, as an indicator of the state of recovery in patients with benign paroxysmal positional vertigo (BPPV). This may confirm the theory of otolith returning into the area of otolithic senses. The study included 48 patients with unilateral posterior semicircular canal BPPV...
December 2017: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29550655/precision-of-perceived-direction-of-gravity-in-partial-bilateral-vestibulopathy-correlates-with-residual-utricular-function
#3
A Bürgin, C J Bockisch, A A Tarnutzer
OBJECTIVE: Gait imbalance in patients with bilateral-vestibular-deficiency (BVD) was linked to increased variability in perceived direction of gravity while upright. We hypothesized this to be true also when roll-tilted. Moreover, as utricular input is essential for spatial orientation, we predicted the variability of perceived vertical to correlate inversely with utricular function. METHODS: Subjective visual vertical (SVV) and haptic vertical (SHV) were measured in various roll-orientations (0°/±45°/±90°) and postural adjustments along earth-vertical/earth-horizontal were collected in patients with partial BVD (n = 10) and healthy controls (n = 11)...
March 5, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29524209/morphology-of-the-utricular-otolith-organ-in-the-toadfish-opsanus-tau
#4
Richard Boyle, Reza Ehsanian, Alireza Mofrad, Yekaterina Popova, Joseph Varelas
The utricle provides the vestibular reflex pathways with the sensory codes of inertial acceleration of self motion and head orientation with respect to gravity to control balance and equilibrium. Here we present an anatomical description of this structure in the adult oyster toadfish, and establish a morphological basis for interpretation of subsequent functional studies. Light, scanning and transmission electron microscopy techniques were applied to visualize the sensory epithelium at varying levels of detail, its neural innervation and its synaptic organization...
March 10, 2018: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/29513752/anti-cancer-characteristics-and-ototoxicity-of-platinum-ii-amine-complexes-with-only-one-leaving-ligand
#5
Jerry D Monroe, Heidi L Hruska, Hannah K Ruggles, Kevin M Williams, Michael E Smith
Unlike cisplatin, which forms bifunctional DNA adducts, monofunctional platinum(II) complexes bind only one strand of DNA and might target cancer without causing auditory side-effects associated with cisplatin treatment. We synthesized the monofunctional triamine-ligated platinum(II) complexes, Pt(diethylenetriamine)Cl, [Pt(dien)Cl]+, and Pt(N,N-diethyldiethylenetriamine)Cl, [Pt(Et2dien)Cl]+, and the monofunctional heterocyclic-ligated platinum(II) complexes, pyriplatin and phenanthriplatin, and compared their 5'-GMP binding rates, cellular compartmental distribution and cellular viability effects...
2018: PloS One
https://www.readbyqxmd.com/read/29432406/examination-of-utricular-response-using-ovemp-and-unilateral-centrifugation-rotation-testing
#6
Christopher K Zalewski, R Steven Ackley, Devin L McCaslin, M Diane Clark, Wendy D Hanks, Carmen C Brewer
OBJECTIVES: Significant advancements have been made toward the clinical assessment of utricular function through ocular vestibular-evoked myogenic potentials (oVEMP) and unilateral centrifugation (UCF) testing. To date, no study has examined intrasubject relationships between these measures. The study hypothesis was that intrasubject responses from oVEMP and UCF testing would be correlated inasmuch as both tests have been reported to assess utricular function. DESIGN: UCF rotations and oVEMP testing were performed on healthy volunteers, aged 18 to 62 years...
February 10, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29357475/location-and-phase-effects-for-ocular-and-cervical-vestibular-evoked-myogenic-potentials-evoked-by-bone-conducted-stimuli-at-midline-skull-sites
#7
Sendhil Govender, James G Colebatch
Our object was to investigate the effect of location and phase on the properties of oVEMPs and cVEMPs evoked by two bone conducted (BC) stimuli, 500 Hz and an impulsive stimulus for midline skull sites from Nz to Iz, in normal volunteers. Compressive and rarefactive onset phases were used and the induced linear and rotational accelerations measured. We confirmed our previous finding of marked changes in the polarity of oVEMPs with location. For cVEMPs using the 500Hz stimulus there were few changes with location or phase, but the impulsive stimulus showed clear phase-related changes at several locations, with the shortest latencies occurring with compressive stimuli at AFz and Fz and the largest amplitudes at Iz...
March 1, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29327737/uphill-downhill-nystagmus
#8
M Gufoni
Differential diagnosis between peripheral and central spontaneous nystagmus can be difficult to classify (as peripheral or central) even on the basis of criteria recommended in the recent literature. The aim of this paper is to use the combination of spontaneous nystagmus and ocular tilt reaction to determine the site of origin of the disease that causes nystagmus. We propose to classify the nystagmus in: 1) "Uphill" nystagmus in which the nystagmus takes on an inclined plane and the direction of the fast phase is towards the hypertropic eye (this type of nystagmus is likely peripheral); 2) "Downhill" nystagmus when the nystagmus beats toward the hypotropic eye (this type of nystagmus is likely central); 3) "Flat" nystagmus when the plane on which nystagmus beats is perfectly horizontal: in this case, we cannot say anything about the site of lesion (it was only detected in 15% of cases)...
December 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29318409/oncomodulin-expression-reveals-new-insights-into-the-cellular-organization-of-the-murine-utricle-striola
#9
Larry F Hoffman, Kristel R Choy, David R Sultemeier, Dwayne D Simmons
Oncomodulin (OCM, aka β-parvalbumin) is an EF-hand calcium binding protein that is expressed in a restricted set of hair cells in the peristriolar region of the mammalian utricle. In the present study, we determined the topologic distribution of OCM among hair cell phenotypes to advance our understanding of the cellular organization of the striola and the relationship of these phenotypes with characteristics of tissue polarity. The distributions of OCM-positive (OCM+) hair cells were quantified in utricles of mature C57Bl/6 mice...
February 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29187759/binocular-cyclotorsion-in-superior-vestibular-neuritis
#10
R Lapenna, A Pellegrino, G Ricci, C Cagini, M Faralli
Conjugated cyclotorsion of the eyes toward the affected side can commonly be observed in vestibular neuritis. The aim of this study was to assess the differences in cyclotorsion between the ipsi- and contralesional eye during selective involvement of the superior branch of the vestibular nerve. We studied binocular cyclotorsion through ocular fundus photographs in 10 patients affected by acute superior vestibular neuritis (SVN). Cyclotorsion was also studied in 20 normal subjects. All SVN patients showed an ipsilesional cycloversion of the eyes...
November 30, 2017: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29142237/inner-ear-otolith-asymmetry-in-late-larval-cichlid-fish-oreochromis-mossambicus-perciformes-showing-kinetotic-behaviour-under-diminished-gravity
#11
Ralf Anken, Miriam Knie, Reinhard Hilbig
The inner ears of all vertebrates are designed to perceive auditory and vestibular inputs. Although a tremendous diversity in the inner ear can be found even among bony fishes, the morphologies of the utricle and of the semicircular canals are rather conservative among vertebrates. Fish show kinetoses under reduced gravity (spinning movements and looping responses) and are regarded model organisms concerning the performance of the otolithic organs. Otoliths can be analysed easily because they are compact, in contrast to the otoconial masses of other vertebrates...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29135871/ocular-vestibular-evoked-myogenic-potentials-where-are-we-now
#12
Julia Dlugaiczyk
OBJECTIVE: Over the last decade, ocular vestibular evoked myogenic potentials (oVEMPs) have evolved as a new clinical test for dynamic otolith (predominantly utricular) function. The aim of this review is to give an update on the neurophysiological foundations of oVEMPs and their implications for recording and interpreting oVEMP responses in clinical practice. CONCLUSION: Different lines of anatomical, neurophysiological, and clinical evidence support the notion that oVEMPs measure predominantly contralateral utricular function, while cervical cVEMPs are an indicator of ipsilateral saccular function...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29017229/ein-neues-lagerungsman%C3%A3-ver-zur-behandlung-einer-form-von-schwankschwindel-auf-der-basis-eines-modifizierten-modells-der-macula-utriculi
#13
Erich Koch
Objectives: A new method for the treatment of a subtype of postural unsteadiness frequently seen in the medical office is proposed. Ten years of successful practical application and continuous refining of this new treatment lead to the definition of symptom-criteria, which are useful to distinguish patients, who get benefit by this new procedure and to a modified model of the utricular macula. Materials and Methods: In a retrospective collection, the data of 15 patients with postural unsteadiness (mean duration of symptoms 61...
October 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28931463/severe-streptomycin-ototoxicity-in-the-mouse-utricle-leads-to-a-flat-epithelium-but-the-peripheral-neural-degeneration-is-delayed
#14
Guo-Peng Wang, Ishani Basu, Lisa A Beyer, Hiu Tung Wong, Donald L Swiderski, Shu-Sheng Gong, Yehoash Raphael
The damaged vestibular sensory epithelium of mammals has a limited capacity for spontaneous hair cell regeneration, which largely depends on the transdifferentiation of surviving supporting cells. Little is known about the response of vestibular supporting cells to a severe insult. In the present study, we evaluated the impact of a severe ototoxic insult on the histology of utricular supporting cells and the changes in innervation that ensued. We infused a high dose of streptomycin into the mouse posterior semicircular canal to induce a severe lesion in the utricle...
November 2017: Hearing Research
https://www.readbyqxmd.com/read/28865839/ovemp-as-an-objective-indicator-of-successful-repositioning-maneuver
#15
Samir Asal, Osama Sobhy, Amany Balbaa
BACKGROUND AND OBJECTIVE: Benign paroxysmal positioning vertigo (BPPV) is the most common peripheral vestibular disorder. Canalolithiasis in the posterior semi-circular canal is the most common underlying pathology that can be treated effectively by repositioning maneuvers. Our hypothesis suggested that successful maneuvers can lead to repositioning of dislodged otoconia to the utricle. MATERIALS AND METHODS: Air conducted oVEMP, which is thought to originate from the contra-lateral utricular organ was measured in twenty patients with unilateral BPPV and we compared n1-p1 peak to peak amplitude of the affected ears in 3 separate intervals: on pre-treatment when typical nystagmus was confirmed, immediately after, and 1 week after repositioning maneuvers to assess change, if any, in amplitude...
August 30, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28816686/vestibular-response-to-electrical-stimulation-of-the-otolith-organs-implications-in-the-development-of-a-vestibular-implant-for-the-improvement-of-the-sensation-of-gravitoinertial-accelerations
#16
Angel Ramos de Miguel, Juan Carlos Falcon Gonzalez, Angel Ramos Macias
OBJECTIVE: Electrical stimulation of the utricular and saccular portions of the vestibular nerve improves stability in patients suffering from vestibular dysfunction. The main objective of this study was to evaluate a new technique, vestibular response telemetry (VRT), for measuring the electrically evoked vestibular compound action potential (saccular and utricular) after stimulating the otolith organ (saccular and utricular) in adults. This study used evidence that the otolith organ can be electrically stimulated in order to develop a new vestibular implant design to improve the sensation of gravitoinertial acceleration...
August 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28798718/vestibular-modulation-of-sympathetic-nerve-activity-to-muscle-and-skin-in-humans
#17
REVIEW
Elie Hammam, Vaughan G Macefield
We review the existence of vestibulosympathetic reflexes in humans. While several methods to activate the human vestibular apparatus have been used, galvanic vestibular stimulation (GVS) is a means of selectively modulating vestibular afferent activity via electrodes over the mastoid processes, causing robust vestibular illusions of side-to-side movement. Sinusoidal GVS (sGVS) causes partial entrainment of sympathetic outflow to muscle and skin. Modulation of muscle sympathetic nerve activity (MSNA) from vestibular inputs competes with baroreceptor inputs, with stronger temporal coupling to the vestibular stimulus being observed at frequencies remote from the cardiac frequency; "super entrainment" was observed in some individuals...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28742024/elastic-force-restricts-growth-of-the-murine-utricle
#18
Ksenia Gnedeva, Adrian Jacobo, Joshua D Salvi, Aleksandra A Petelski, A J Hudspeth
Dysfunctions of hearing and balance are often irreversible in mammals owing to the inability of cells in the inner ear to proliferate and replace lost sensory receptors. To determine the molecular basis of this deficiency we have investigated the dynamics of growth and cellular proliferation in a murine vestibular organ, the utricle. Based on this analysis, we have created a theoretical model that captures the key features of the organ's morphogenesis. Our experimental data and model demonstrate that an elastic force opposes growth of the utricular sensory epithelium during development, confines cellular proliferation to the organ's periphery, and eventually arrests its growth...
July 25, 2017: ELife
https://www.readbyqxmd.com/read/28690584/decompression-in-chiari-malformation-clinical-ocular-motor-cerebellar-and-vestibular-outcome
#19
Nicolina Goldschagg, Katharina Feil, Franziska Ihl, Siegbert Krafczyk, Mathias Kunz, Jörg Christian Tonn, Michael Strupp, Aurelia Peraud
BACKGROUND: Treatment of Chiari malformation can include suboccipital decompression with resection of one cerebellar tonsil. Its effects on ocular motor and cerebellar function have not yet been systematically examined. OBJECTIVE: To investigate whether decompression, including resection of one cerebellar tonsil, leads to ocular motor, vestibular, or cerebellar deficits. PATIENTS AND METHODS: Ten patients with Chiari malformation type 1 were systematically examined before and after (1 week and 3 months) suboccipital decompression with unilateral tonsillectomy...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28681630/residual-dizziness-after-successful-treatment-of-idiopathic-benign-paroxysmal-positional-vertigo-originates-from-persistent-utricular-dysfunction
#20
Toru Seo, Ko Shiraishi, Takaaki Kobayashi, Kitano Mutsukazu, Takeshi Fujita, Kazuya Saito, Hiroyasu Watanabe, Katsumi Doi
OBJECTIVE: We used ocular vestibular evoked myogenic potentials to investigate the relationship between residual dizziness and utricular function following the canalith repositioning procedure for benign paroxysmal positional vertigo. METHODS: Ocular vestibular evoked myogenic potentials were measured in 44 patients (40 included in analyses, four excluded) with successful results from the canalith repositioning procedure. The patients were examined before treatment and again one week after treatment...
November 2017: Acta Oto-laryngologica
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