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https://www.readbyqxmd.com/read/28518122/dorsal-root-ganglion-injection-and-dorsal-root-crush-injury-as-a-model-for-sensory-axon-regeneration
#1
Menghon Cheah, James W Fawcett, Melissa R Andrews
Achieving axon regeneration after nervous system injury is a challenging task. As different parts of the central nervous system (CNS) differ from each other anatomically, it is important to identify an appropriate model to use for the study of axon regeneration. By using a suitable model, we can formulate a specific treatment based on the severity of injury, the neuronal cell type of interest, and the desired spinal tract for assessing regeneration. Within the sensory pathway, DRG neurons are responsible for relaying sensory information from the periphery to the CNS...
May 3, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28508734/the-role-of-cue-utilisation-in-reducing-the-workload-in-a-train-control-task
#2
Sue Brouwers, Mark W Wiggins, Barbara Griffin, William S Helton, David O'Hare
Skilled performance has been characterised, in part, by the capacity to accurately identify and respond to patterns as cues in the environment. The outcome is a reduction in cognitive load and a greater residual capacity to undertake concurrent tasks. The present study was designed to examine the relationship between cue utilisation and temporal pattern recognition in the context of a simulated, rail control task. Sixty-one university students undertook an assessment of cue utilisation and engaged in a rail control simulation...
May 16, 2017: Ergonomics
https://www.readbyqxmd.com/read/28507035/long-term-sensitization-training-in-aplysia-decreases-the-excitability-of-a-decision-making-neuron-through-a-sodium-dependent-mechanism
#3
John S Hernandez, Marcy L Wainwright, Riccardo Mozzachiodi
In Aplysia, long-term sensitization (LTS) occurs concurrently with a suppression of feeding. At the cellular level, the suppression of feeding is accompanied by decreased excitability of decision-making neuron B51. We examined the contribution of voltage-gated Na(+) and K(+) channels to B51 decreased excitability. In a pharmacologically isolated Na(+) channels environment, LTS training significantly increased B51 firing threshold, compared with untrained controls. Conversely, in a pharmacologically isolated K(+) channels environment, no differences were observed between trained and untrained animals in either amplitude or area of B51 K(+)-dependent depolarizations...
June 2017: Learning & Memory
https://www.readbyqxmd.com/read/28503530/caffeine-supplementation-affects-the-immunometabolic-response-to-concurrent-training
#4
Fabrício Eduardo Rossi, Valéria Leme Gonçalves Panissa, Paula Aulves Monteiro, José Gerosa-Neto, Érico Chagas Caperuto, Jason Michael Cholewa, Alessandro Moura Zagatto, Fábio Santos Lira
The aim of the present study was to investigate the effects of caffeine (CAF) and carbohydrate (CHO) intake on strength performance and its metabolic and inflammatory responses during concurrent training. Seven active males ingested a double-placebo (P), CAF (capsule 5 mg/kg) or CHO (20% maltodextrin solution) supplementation before strength exercise. Participants performed three randomized sessions of 5,000-m high-intensity intermittent aerobic exercise at maximal intensity followed by strength exercise, performing after the P, CHO, and CAF intake...
April 2017: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28503145/a-neural-dynamic-architecture-for-concurrent-estimation-of-object-pose-and-identity
#5
Oliver Lomp, Christian Faubel, Gregor Schöner
Handling objects or interacting with a human user about objects on a shared tabletop requires that objects be identified after learning from a small number of views and that object pose be estimated. We present a neurally inspired architecture that learns object instances by storing features extracted from a single view of each object. Input features are color and edge histograms from a localized area that is updated during processing. The system finds the best-matching view for the object in a novel input image while concurrently estimating the object's pose, aligning the learned view with current input...
2017: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/28498204/asds-guidelines-task-force-consensus-recommendations-regarding-the-safety-of-lasers-dermabrasion-chemical-peels-energy-devices-and-skin-surgery-during-and-after-isotretinoin-use
#6
Abigail Waldman, Diana Bolotin, Kenneth A Arndt, Jeffrey S Dover, Roy G Geronemus, Anne Chapas, Sanjana Iyengar, Suzanne L Kilmer, Andrew C Krakowski, Naomi Lawrence, Heidi B Prather, Thomas E Rohrer, Bethanee J Schlosser, John Y S Kim, Peter R Shumaker, Leah K Spring, Murad Alam
BACKGROUND: Currently, the isotretinoin (13-cis-retinoic acid) package insert contains language advising the discontinuation of isotretinoin for 6 months before performing cosmetic procedures, including waxing, dermabrasion, chemical peels, laser procedures, or incisional and excisional cold-steel surgery. It is common practice to follow this standard because of concerns regarding reports of sporadic adverse events and increased risk of scarring. OBJECTIVE: To develop expert consensus regarding the safety of skin procedures, including resurfacing, energy device treatments, and incisional and excisional procedures, in the setting of concurrent or recent isotretinoin use...
May 10, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28476323/the-malnutrition-screening-tool-in-geriatric-rehabilitation-a-comparison-of-validity-when-completed-by-health-professionals-with-and-without-malnutrition-screening-training-has-implications-for-practice
#7
Skye Marshall, Adrienne Young, Elizabeth Isenring
BACKGROUND: The validity of the Malnutrition Screening Tool (MST) in geriatric rehabilitation has been evaluated in a research environment but not in professional practice. OBJECTIVE: In older adults admitted to rehabilitation, this study was undertaken to compare the MST scoring agreement (inter-rater reliability) between health professionals with and without malnutrition risk and screening training; to evaluate the concurrent validity of the MST completed by the trained and untrained health professionals compared to the International Classification of Diseases, Tenth Revision, Australian Modification using different MST score cutoffs; and to determine whether patient characteristics were associated with MST scoring accuracy when completed by health professionals without malnutrition risk and screening training...
May 2, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28476278/reliability-and-validity-of-the-treatment-outcome-profile-among-patients-attending-methadone-maintenance-treatment-programs-in-kunming-china
#8
Mei Wang, Jiucheng Shen, Xianling Liu, Yuan Deng, Jiahua Li, Emily Finch, Kim Wolff
BACKGROUND & OBJECTIVE: Substance misuse has been a major health and social issue worldwide and has become an important public health issue in China over the past two decades. Methadone maintenance treatment (MMT) has been proved worldwide by large bodies of research to be one of the most effective practices for illicit drug users. The Treatment Outcome Profile (TOP) was developed in 2007 by the UK National Treatment Agency (NTA). It has been proved to be a reliable instrument for outcome measure...
June 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28472313/implementing-evidence-based-palliative-care-programs-and-policy-for-cancer-patients-epidemiologic-and-policy-implications-of-the-2016-american-society-of-clinical-oncology-clinical-practice-guideline-update
#9
Sarina R Isenberg, Rebecca A Aslakson, Thomas J Smith
The American Society of Clinical Oncology (ASCO) recently convened an Ad Hoc Palliative Care Expert Panel to update a 2012 provisional clinical opinion by conducting a systematic review of clinical trials in palliative care in oncology. The key takeaways from the updated ASCO clinical practice guidelines (CPGs) are that more people should be referred to interdisciplinary palliative care teams and that more palliative care specialists and palliative care-trained oncologists are needed to meet this demand. The following summary statement is based on multiple randomized clinical trials: "Inpatients and outpatients with advanced cancer should receive dedicated palliative care services, early in the disease course, concurrent with active treatment...
January 1, 2017: Epidemiologic Reviews
https://www.readbyqxmd.com/read/28471217/number-prompts-left-to-right-spatial-mapping-in-toddlerhood
#10
Koleen McCrink, Jasmin Perez, Erica Baruch
Toddlers performed a spatial mapping task in which they were required to learn the location of a hidden object in a vertical array and then transpose this location information 90° to a horizontal array. During the vertical training, they were given (a) no labels, (b) alphabetical labels, or (c) numerical labels for each potential spatial location. After the array was transposed to become a horizontal continuum, the children who were provided with numerical labels during training and those who heard alphabetical labels and formed a strong memory for the vertical location, selectively chose the location corresponding to a left-to-right mapping bias...
May 4, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28462571/effects-of-minimal-dose-of-strength-training-on-running-performance-in-female-recreational-runners
#11
Michal Štohanzl, Jiri Baláš, Nick Draper
BACKGROUND: The purpose of this study was to analyse the extent to which minimal dose strength training would elicit improvements in running performance for female recreational runners. METHODS: Forty-one female recreational runners were randomly assigned to one of three groups (endurance running [E] n=14; combined endurance running and strength training program once [ES30] n=14 and twice a week [ES60] n=13, respectively). During the 10-week training program, the E group completed 3 hours of continuous endurance running per week; ES30 completed 2 ½ hours of continuous endurance running and 1 x 30 min of strength training per week, while ES60 group completed 2 hours of continuous endurance running and 2x30 min of strength training per week...
April 28, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28461217/multisensory-integration-in-short-term-memory-musicians-do-rock
#12
Avigael M Aizenman, Jason M Gold, Robert Sekuler
Demonstrated interactions between seeing and hearing led us to assess the link between music training and short-term memory for auditory, visual and audiovisual sequences of rapidly presented, quasi-random components. Visual sequences' components varied in luminance; auditory sequences' components varied in frequency. Concurrent components in audiovisual sequences were either congruent (the frequency of an auditory item increased monotonically with the luminance of the visual item it accompanied), or incongruent (an item's frequency was uncorrelated with luminance of the item it accompanied)...
April 29, 2017: Neuroscience
https://www.readbyqxmd.com/read/28457587/integration-of-mental-health-screening-in-the-management-of-patients-with-temporomandibular-disorders
#13
E Yeung, A Abou-Foul, F Matcham, T Poate, K Fan
Mental health disorders such as depression or anxiety, or both, are more common in patients with temporomandibular disorders (TMD) (16%-40%) than in the general population (16%), and failure to recognise them may be detrimental to the management of TMD. Paper-based screening tools previously reported in this group require assessment by clinicians and subsequent collation of data. We describe our experience of a new system - IMPARTS (Integrating mental and physical: research training and services), which uses validated tools to identify and to monitor the progress of patients who may benefit from psychological intervention...
April 27, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28456169/reservoir-observers-model-free-inference-of-unmeasured-variables-in-chaotic-systems
#14
Zhixin Lu, Jaideep Pathak, Brian Hunt, Michelle Girvan, Roger Brockett, Edward Ott
Deducing the state of a dynamical system as a function of time from a limited number of concurrent system state measurements is an important problem of great practical utility. A scheme that accomplishes this is called an "observer." We consider the case in which a model of the system is unavailable or insufficiently accurate, but "training" time series data of the desired state variables are available for a short period of time, and a limited number of other system variables are continually measured. We propose a solution to this problem using networks of neuron-like units known as "reservoir computers...
April 2017: Chaos
https://www.readbyqxmd.com/read/28445221/changes-in-personal-relationships-during-residency-and-their-effects-on-resident-wellness-a-qualitative-study
#15
Marcus Law, Michelle Lam, Diana Wu, Paula Veinot, Maria Mylopoulos
PURPOSE: Residency poses challenges for residents' personal relationships. Research suggests residents rely on family and friends for support during their training. The authors explored the impact of residency demands on residents' personal relationships and the effects changes in those relationships could have on their wellness. METHOD: The authors used a constructivist grounded theory approach. In 2012-2014, they conducted semistructured interviews with a purposive and theoretical sample of 16 Canadian residents from various specialties and training levels...
April 25, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28443006/cognitive-resources-necessary-for-motor-control-in-older-adults-are-reduced-by-walking-and-coordination-training
#16
Ben Godde, Claudia Voelcker-Rehage
We examined if physical exercise interventions were effective to reduce cognitive brain resources recruited while performing motor control tasks in older adults. Forty-three older adults (63-79 years of age) participated in either a walking (n = 17) or a motor coordination (n = 15) intervention (1 year, 3 times per week) or were assigned to a control group (n = 11) doing relaxation and stretching exercises. Pre and post the intervention period, we applied functional MRI to assess brain activation during imagery of forward and backward walking and during counting backwards from 100 as control task...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28442274/sex-differences-in-exercise-efficacy-to-improve-cognition-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials-in-older-humans
#17
REVIEW
Cindy K Barha, Jennifer C Davis, Ryan S Falck, Lindsay S Nagamatsu, Teresa Liu-Ambrose
Exercise is a non-pharmacological strategy to mitigate the deleterious effects of aging on brain health. However, a large amount of variation exists in its efficacy. Sex of participants and exercise type are two possible factors contributing to this variation. To better understand this, we conducted a concurrent systematic review and meta-analysis of cognitively healthy older adults. Executive functions, episodic memory, visuospatial function, word fluency, processing speed and global cognitive function were examined for exercise- and sex-dependent effects...
April 22, 2017: Frontiers in Neuroendocrinology
https://www.readbyqxmd.com/read/28441406/head-and-pelvic-movement-asymmetries-at-trot-in-riding-horses-in-training-and-perceived-as-free-from-lameness-by-the-owner
#18
Marie Rhodin, Agneta Egenvall, Pia Haubro Andersen, Thilo Pfau
Recent studies evaluating horses in training and considered free from lameness by their owners have identified a large proportion of horses with motion asymmetries. However the prevalence, type and magnitude of asymmetries when trotting in a straight line or on the lunge have not been investigated. The aim of this study was to objectively investigate the presence of motion asymmetries in riding horses in training by identifying the side and quantifying the degree and type (impact, pushoff) of forelimb and hind limb asymmetries found during straight line trot and on the lunge...
2017: PloS One
https://www.readbyqxmd.com/read/28439362/use-of-a-90-minute-admission-window-and-front-fill-system-to-reduce-work-compression-on-a-general-medicine-inpatient-teaching-service
#19
Youngjee Choi, Daniel Kim, Hyemi Chong, Christopher Mallow, Jason Bill, Anthony T Fojo, Melvin Blanchard
BACKGROUND: Duty hour limits have shortened intern shifts without concurrent reductions in workload, creating work compression. Multiple admissions during shortened shifts can result in poor training experience and patient care. OBJECTIVE: To relieve work compression, improve resident satisfaction, and improve duty hour compliance in an academic internal medicine program. METHODS: In 2014, interns on general ward services were allotted 90 minutes per admission from 3 pm to 7 pm, when the rate of admissions was high...
April 2017: Journal of Graduate Medical Education
https://www.readbyqxmd.com/read/28439357/resident-dyads-providing-transition-care-to-adolescents-and-young-adults-with-chronic-illnesses-and-neurodevelopmental-disabilities
#20
Richard J Chung, Joan Jasien, Gary R Maslow
BACKGROUND: Youth with special health care needs often experience difficulty transitioning from pediatric to adult care. These difficulties may derive in part from lack of physician training in transition care and the challenges health care providers experience establishing interdisciplinary partnerships to support these patients. OBJECTIVE: This educational innovation sought to improve pediatrics and adult medicine residents' interdisciplinary communication and collaboration...
April 2017: Journal of Graduate Medical Education
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