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https://www.readbyqxmd.com/read/29330217/a-systematic-review-of-network-meta-analyses-for-pharmacological-treatment-of-common-mental-disorders
#1
REVIEW
Taryn Williams, Dan J Stein, Jonathan Ipser
QUESTION: Network meta-analyses (NMAs) of treatment efficacy across different pharmacological treatments help inform clinical decision-making, but their methodological quality may vary a lot depending also on the quality of the included primary studies. We therefore conducted a systematic review of NMAs of pharmacological treatment for common mental disorders in order to assess the methodological quality of these NMAs, and to relate study characteristics to the rankings of efficacy and tolerability...
January 12, 2018: Evidence-based Mental Health
https://www.readbyqxmd.com/read/29321077/social-anxiety-disorder-looking-back-and-moving-forward
#2
Matthew P Hyett, Peter M McEvoy
Fifty years have passed since social anxiety disorder (SAD) was first differentiated from other phobias. In the years since research has largely aligned with the zeitgeist of categorical classificatory frameworks, and has spanned identifying causes, maintenance factors and innovative interventions. Despite significant advances in the field, the capacity to conceptualise SAD as an independent entity is limited given the heterogeneity and dimensionality of diagnostic criteria, high rates of comorbidity, and non-specificity of aetiological mechanisms, maintaining factors and approaches to treatment...
January 11, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29306023/short-versions-of-two-specific-phobia-measures-the-snake-and-the-spider-questionnaires
#3
Andras N Zsido, Nikolett Arato, Orsolya Inhof, Jozsef Janszky, Gergely Darnai
Zoophobias are the most prevalent form of specific phobia worldwide. Two of the most widely used measures, the Snake Questionnaire (SNAQ) and Spider Questionnaire (SPQ) are good indicators of specific fears, but researchers have recognised that shorter, yet nevertheless reliable measures are needed. Hence the aims of this research were to develop short forms of the SNAQ and SPQ using item response theory and to use receiver operating characteristic (ROC) curve analyses to determine cut-offs for use in future research...
December 30, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29281096/relating-experimentally-induced-fear-to-pre-existing-phobic-fear-in-the-human-brain
#4
Seth M Levine, Michael Pfaller, Jonas Reichenberger, Youssef Shiban, Andreas Mühlberger, Rainer Rupprecht, Jens V Schwarzbach
While prior work has demonstrated that fear-conditioning changes the neural representation of previously neutral stimuli, it remains unknown to what extent this new representation abstracts away from specific fears and which brain areas are involved therein. To investigate this question, we sought commonalities between experimentally-induced fear via electric shocks and pre-existing phobia. Using functional MRI, we tested the effect of fear-conditioning pictures of dogs in 21 spider-fearful participants across three phases: baseline, post-conditioning, and extinction...
December 21, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29277320/phenomenology-epidemiology-co-morbidity-and-treatment-of-a-specific-phobia-of-vomiting-a-systematic-review-of-an-understudied-disorder
#5
REVIEW
Alexandra Keyes, Helen R Gilpin, David Veale
Specific Phobia of Vomiting (SPOV) is an under-researched disorder compared to other Specific Phobias. A systematic review was conducted to synthesise existing research across areas of phenomenology, aetiology, epidemiology, co-morbidity, assessment measures and treatment. Online databases (Psychinfo, Embase, Medline, Pubmed and Cochrane Library) were searched using terms related to SPOV and 'emetophobia'. A manual search of reference lists of included papers was also conducted. In total, 385 articles were found and 24 were included in the review...
December 12, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29276896/outcome-of-depressive-and-anxiety-disorders-among-young-adults-results-from-the-longitudinal-finnish-health-2011-study
#6
Teija Kasteenpohja, Mauri Marttunen, Terhi Aalto-Setälä, Jonna Perälä, Samuli I Saarni, Jaana Suvisaari
PURPOSE OF THE STUDY: We investigated the outcomes and outcome predictors of depressive and anxiety disorders in a general population sample of young adults with a lifetime history of these disorders. MATERIALS AND METHODS: The study sample was derived from a nationally representative two-stage cluster sample of Finns aged 19-34 years. The original study was carried out in 2003-2005, and the follow-up in 2011. We investigated participants diagnosed with a depressive or anxiety disorder based on a SCID interview (excluding those with only a single specific phobia) (DAX-group, N = 181)...
December 25, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29223798/self-reported-volitional-control-in-adolescents-and-young-adults-from-a-community-cohort-associations-with-current-past-and-future-mental-disorders
#7
Eva Asselmann, Kevin Hilbert, Jana Hoyer, Hans-Ulrich Wittchen, Roselind Lieb, Gerhard Bühringer, Katja Beesdo-Baum
Alterations in volitional control have been found for various mental disorders. However, it remains unclear to which degree such alterations vary by type of psychopathology and constitute preceding vulnerabilities or correlates of mental disorders. DSM-IV mental disorders were assessed among adolescents and young adults from the community at baseline (age 14-24) and in up to 3 follow-up assessments over 10 years (n = 2515) using a standardized diagnostic interview (DIA-X/M-CIDI). Self-reported volitional control was assessed at second follow-up (T2) when subjects were aged 17-28 using the German version of the Short Form of the Volitional Components Inventory...
November 21, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29213247/mediating-effects-of-global-negative-effect-expectancies-on-the-association-between-problematic-cannabis-use-and-social-anxiety
#8
Maria Di Blasi, Paola Cavani, Laura Pavia, Crispino Tosto, Sabina La Grutta, Rosa Lo Baido, Cecilia Giordano, Adriano Schimmenti
The relationship between social anxiety (SA) and cannabis use among adolescents and young adults is a highly debated topic. In this cross-sectional study, we tested whether cannabis use expectancies mediated the association between SA and cannabis use severity in a sample of 343 young adults (74.3% male) who used cannabis. They completed self-report measures for the screening of problematic cannabis use (Cannabis Use Problems Identification Test) and SA symptoms (Social Interaction Anxiety Scale and Social Phobia Scale)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29212828/detecting-anxiety-in-individuals-with-parkinson-disease-a-systematic-review
#9
Bria Mele, Jayna Holroyd-Leduc, Eric E Smith, Tamara Pringsheim, Zahinoor Ismail, Zahra Goodarzi
OBJECTIVE: To examine diagnostic accuracy of anxiety detection tools compared with a gold standard in outpatient settings among adults with Parkinson disease (PD). METHODS: A systematic review was conducted. MEDLINE, EMABASE, PsycINFO, and Cochrane Database of Systematic Reviews were searched to April 7, 2017. Prevalence of anxiety and diagnostic accuracy measures including sensitivity, specificity, and likelihood ratios were gathered. Pooled prevalence of anxiety was calculated using Mantel-Haenszel-weighted DerSimonian and Laird models...
December 6, 2017: Neurology
https://www.readbyqxmd.com/read/29212134/association-between-attention-bias-to-threat-and-anxiety-symptoms-in-children-and-adolescents
#10
Rany Abend, Leone de Voogd, Elske Salemink, Reinout W Wiers, Koraly Pérez-Edgar, Amanda Fitzgerald, Lauren K White, Giovanni A Salum, Jie He, Wendy K Silverman, Jeremy W Pettit, Daniel S Pine, Yair Bar-Haim
BACKGROUND: Considerable research links threat-related attention biases to anxiety symptoms in adults, whereas extant findings on threat biases in youth are limited and mixed. Inconsistent findings may arise due to substantial methodological variability and limited sample sizes, emphasizing the need for systematic research on large samples. The aim of this report is to examine the association between threat bias and pediatric anxiety symptoms using standardized measures in a large, international, multi-site youth sample...
December 6, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/29156434/we-prefer-what-we-fear-a-response-preference-bias-mimics-attentional-capture-in-spider-fear
#11
Anke Haberkamp, Melanie Biafora, Thomas Schmidt, Katharina Weiß
The extent to which emotionally significant stimuli capture visual attention remains elusive because a preference for reporting or choosing emotionally significant stimuli could mimic attentional capture by these stimuli. We conducted two prior-entry experiments to disentangle whether phobic and fear-relevant stimuli capture attention or merely produce a response bias in spider-fearful participants. Prior entry denotes the effect that attended stimuli are perceived earlier than unattended stimuli as indicated by temporal order judgments...
November 8, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29118158/dental-hygienists-attitudes-toward-the-obese-population
#12
Gwen Essex, Keiko Miyahara, Dorothy J Rowe
Purpose: To explore dental hygienists' attitudes toward the obese population and to determine whether there are differences in attitudes among those with different self-reported body images.Methods: The study population was dental hygienists whose email addresses were in the database of the California Dental Hygienists' Association (CDHA). CDHA distributed the electronic message containing study information, informed consent, and a link to the survey. The survey consisted of 14 items from the Fat Phobia Scale, 13 items from the Anti-fat Attitudes Questionnaire (AFAQ), 3 demographic questions, and 1 question on body image...
December 2016: Journal of Dental Hygiene: JDH
https://www.readbyqxmd.com/read/29101841/the-mediating-role-of-changes-in-harm-beliefs-and-coping-efficacy-in-youth-with-specific-phobias
#13
Thomas H Ollendick, Sarah M Ryan, Nicole N Capriola-Hall, Lena Reuterskiöld, Lars-Göran Öst
Individuals with specific phobias (SPs) often experience catastrophic cognitions and compromised efficacy regarding their ability to cope when in the presence of the phobic object/situation. In the current study, 165 children (7-16 years; 62% male) received either One Session Treatment or Educational Support Therapy for their SP. The children identified their feared belief and rated "how bad" it was, "how likely" it was to occur, and their ability to cope if it did occur. All of these ratings were reduced from pre-treatment to 6-month follow-up, across both treatment conditions...
October 18, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29096207/avoidant-personality-disorder-and-social-phobia-does-mindreading-make-the-difference
#14
Giovanni Pellecchia, Fabio Moroni, Livia Colle, Antonio Semerari, Antonino Carcione, Teresa Fera, Donatella Fiore, Giuseppe Nicolò, Roberto Pedone, Michele Procacci
OBJECTIVE: Avoidant personality disorder (AvPD) is closely related to and partially overlaps with social phobia (SP). There is an ongoing debate as to whether AvPD and SP can be classified as separate and distinct disorders or whether these diagnoses rather reflect different degrees of severity of social anxiety. The hypothesis of this study is that in patients with AvPD and in those with AvPD and comorbid SP both interpersonal functioning and metacognitive abilities (the ability to understand mental states) are more severely impaired than they are in patients with SP only...
September 28, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/29054435/networks-of-phobic-fear-functional-connectivity-shifts-in-two-subtypes-of-specific-phobia
#15
Maria R Stefanescu, Ralph J Endres, Kevin Hilbert, Hans-Ulrich Wittchen, Ulrike Lueken
Anxiety disorders can be conceptualized by an abnormal interplay of emotion-processing brain circuits; however, knowledge of brain connectivity measures in specific phobia is still limited. To explore functional interactions within selected fear-circuitry structures (anterior cingulate cortex (ACC), amygdala, insula), we re-examined three task-based fMRI studies using a symptom provocation approach (n=94 subjects in total) on two different phobia subtypes (animal subtype as represented by snake phobia (SP) and blood-injection-injury subtype as represented by dental phobia (DP)), and a non-phobic healthy control group (HC)...
October 18, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29053980/incident-mental-disorders-in-the-aftermath-of-traumatic-events-a-prospective-longitudinal-community-study
#16
Eva Asselmann, Hans-Ulrich Wittchen, Roselind Lieb, Axel Perkonigg, Katja Beesdo-Baum
BACKGROUND: Few strictly prospective-longitudinal community studies examined the role of traumatic events for risk of developing a broad range of incident mental disorders over several years. METHOD: A representative community sample of adolescents and young adults (n = 2797, baseline age 14-24) was prospectively examined in up to three assessment waves over up to 10 years. Traumatic events and DSM-IV mental disorders were assessed at each wave using the DIA-X/M-CIDI...
October 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29037266/is-cognitive-behavioural-therapy-more-effective-than-relaxation-therapy-in-the-treatment-of-anxiety-disorders-a-meta-analysis
#17
Jesus Montero-Marin, Javier Garcia-Campayo, Alba López-Montoyo, Edurne Zabaleta-Del-Olmo, Pim Cuijpers
BACKGROUND: It is not clear whether relaxation therapies are more or less effective than cognitive and behavioural therapies in the treatment of anxiety. The aims of the present study were to examine the effects of relaxation techniques compared to cognitive and behavioural therapies in reducing anxiety symptoms, and whether they have comparable efficacy across disorders. METHOD: We conducted a meta-analysis of 50 studies (2801 patients) comparing relaxation training with cognitive and behavioural treatments of anxiety...
October 17, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29034525/reliability-and-validity-of-severity-dimensions-of-psychopathology-assessed-using-the-structured-clinical-interview-for-dsm-5-scid
#18
Stewart A Shankman, Carter J Funkhouser, Daniel N Klein, Joanne Davila, Debra Lerner, Danelle Hee
This study examined whether the Structured Clinical Interview for DSM (SCID), a widely used semistructured interview designed to assess psychopathology categorically, can be adapted to identify reliable and valid severity dimensions of psychopathology. The present study also examined whether these severity dimensions have better psychometric properties (internal consistency, test-retest reliability, and concurrent and predictive validity) than categorical diagnoses. Participants (N = 234) were recruited from the community and clinics...
October 16, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/29028150/potential-of-micrornas-as-novel-targets-in-the-alleviation-of-pathological-fear
#19
REVIEW
Conor P Murphy, Nicolas Singewald
The current treatment of post-traumatic stress disorder (PTSD), phobias and other anxiety disorders, remains insufficient particularly in producing long-lasting full symptom control. Dysfunctional fear processing is common in these disorders, including a deficiency in fear-inhibitory mechanisms and impairment in the ability to discriminate between safety and danger cues. Research has aimed to elucidate brain circuitries, neurotransmitters and downstream signaling pathways important in the alleviation of aberrant fear, with a specific focus on mechanisms modulating fear memory and its behavioral expression...
October 13, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29027588/mental-disorders-and-the-risk-for-the-subsequent-first-suicide-attempt-results-of-a-community-study-on-adolescents-and-young-adults
#20
Marcel Miché, Patrizia Denise Hofer, Catharina Voss, Andrea Hans Meyer, Andrew Thomas Gloster, Katja Beesdo-Baum, Roselind Lieb
Adolescents and young adults represent the high-risk group for first onset of both DSM-IV mental disorders and lifetime suicide attempt (SA). Yet few studies have evaluated the temporal association of prior mental disorders and subsequent first SA in a young community sample. We examined (a) such associations using a broad range of specific DSM-IV mental disorders, (b) the risk of experiencing the outcome due to prior comorbidity, and (c) the proportion of SAs that could be attributed to prior disorders. During a 10-year prospective study, data were gathered from 3021 community subjects, 14-24 years of age at baseline...
October 11, 2017: European Child & Adolescent Psychiatry
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