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https://www.readbyqxmd.com/read/28321945/quantitative-representations-of-an-exaggerated-anxiety-response-in-the-brain-of-female-spider-phobics-a-parametric-fmri-study
#1
Anna Zilverstand, Bettina Sorger, Anita Kaemingk, Rainer Goebel
We employed a novel parametric spider picture set in the context of a parametric fMRI anxiety provocation study, designed to tease apart brain regions involved in threat monitoring from regions representing an exaggerated anxiety response in spider phobics. For the stimulus set, we systematically manipulated perceived proximity of threat by varying a depicted spider's context, size, and posture. All stimuli were validated in a behavioral rating study (phobics n = 20; controls n = 20; all female). An independent group participated in a subsequent fMRI anxiety provocation study (phobics n = 7; controls n = 7; all female), in which we compared a whole-brain categorical to a whole-brain parametric analysis...
March 21, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28300935/specific-and-social-fears-in-children-and-adolescents-separating-normative-fears-from-problem-indicators-and-phobias
#2
Paola P Laporte, Pedro M Pan, Mauricio S Hoffmann, Lauren S Wakschlag, Luis A Rohde, Euripedes C Miguel, Daniel S Pine, Gisele G Manfro, Giovanni A Salum
Objective: To distinguish normative fears from problematic fears and phobias. Methods: We investigated 2,512 children and adolescents from a large community school-based study, the High Risk Study for Psychiatric Disorders. Parent reports of 18 fears and psychiatric diagnosis were investigated. We used two analytical approaches: confirmatory factor analysis (CFA)/item response theory (IRT) and nonparametric receiver operating characteristic (ROC) curve. Results: According to IRT and ROC analyses, social fears are more likely to indicate problems and phobias than specific fears...
March 9, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28273888/the-experience-of-social-exclusion-in-women-with-a-history-of-suicidal-acts-a-neuroimaging-study
#3
Emilie Olié, Fabrice Jollant, Jeremy Deverdun, Nicolas Menjot de Champfleur, Fabienne Cyprien, Emmanuelle Le Bars, Thibaut Mura, Alain Bonafé, Philippe Courtet
Suicidal behaviors result from a complex interaction between social stressors and individual vulnerability. However, little is known of the specific neural network supporting the sensitivity to social stressors in patients at risk of suicidal acts. Using functional Magnetic Resonance Imaging, we investigated brain processing of social rejection in suicide attempters. Thirty-six euthymic women with a history of depression and suicidal behavior were compared to 41 euthymic women with a history of depression but no suicidal attempt, and 28 healthy controls...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28270029/treatment-of-intra-oral-injection-phobia-a-randomized-delayed-intervention-controlled-trial-among-norwegian-10-to-16-year-olds
#4
Karin G Berge, Maren Lillehaug Agdal, Margrethe Vika, Marit Slåttelid Skeie
OBJECTIVE: To evaluate the effect of five sessions of cognitive behavioural therapy (CBT) for 10- to 16-year-olds with intra-oral injection phobia. MATERIAL AND METHODS: This was a randomized delayed intervention controlled trial in 67 patients, fulfilling the DSM-5 criteria for specific phobia. All patients received the same CBT performed by dentists specially trained in CBT. The patients were randomly assigned to either an immediate treatment group (ITG) (34 patients) or a waitlist-control group (WCG) (33 patients)...
March 7, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28259723/influence-of-single-dose-quetiapine-on-fear-network-activity-a-pharmaco-imaging-study
#5
J Diemer, P Zwanzger, I Fohrbeck, M Zavorotnyy, S Notzon, K Silling, V Arolt, K Domschke, B Pfleiderer
OBJECTIVE: Anxiety disorders are among the most frequent psychiatric disorders. Current treatment guidelines recommend antidepressants, the calcium modulator gabapentin, and benzodiazepines as pharmacological treatments. However, delayed onset of action precludes the use of antidepressants as an acute treatment, while benzodiazepines can be recommended only as an emergency treatment due to their inherent risk of dependence. Therefore, an alternative pharmacological agent with acute efficacy is needed...
March 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28245844/topical-corticosteroid-phobia-in-parents-of-pediatric-patients-with-atopic-dermatitis-a-multicentre-survey
#6
Maya El Hachem, Francesco Gesualdo, Giampaolo Ricci, Andrea Diociaiuti, Loredana Giraldi, Orsola Ametrano, Corrado Occella, Anna Belloni Fortina, Mirella Milioto, Fabio Arcangeli, Oriana Simonetti, Simona Giancristoforo, Elisabetta Calamelli, Carlo Mazzatenta, Iria Neri
BACKGROUND: Families of children affected with atopic dermatitis (AD) often report fear and anxiety regarding treatment with topical corticosteroids (TCS), which may lead to reduced compliance. The objective of our study was to measure, through a standardized questionnaire, fear of TCS in families of pediatric patients with AD and to identify items associated with fear. METHODS: Families of pediatric patients with AD were enrolled in 9 Italian centers of pediatric dermatology...
February 28, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28222820/the-cross-national-epidemiology-of-specific-phobia-in-the-world-mental-health-surveys
#7
K J Wardenaar, C C W Lim, A O Al-Hamzawi, J Alonso, L H Andrade, C Benjet, B Bunting, G de Girolamo, K Demyttenaere, S E Florescu, O Gureje, T Hisateru, C Hu, Y Huang, E Karam, A Kiejna, J P Lepine, F Navarro-Mateu, M Oakley Browne, M Piazza, J Posada-Villa, M L Ten Have, Y Torres, M Xavier, Z Zarkov, R C Kessler, K M Scott, P de Jonge
BACKGROUND: Although specific phobia is highly prevalent, associated with impairment, and an important risk factor for the development of other mental disorders, cross-national epidemiological data are scarce, especially from low- and middle-income countries. This paper presents epidemiological data from 22 low-, lower-middle-, upper-middle- and high-income countries. METHOD: Data came from 25 representative population-based surveys conducted in 22 countries (2001-2011) as part of the World Health Organization World Mental Health Surveys initiative (n = 124 902)...
February 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28210232/confirmatory-factor-analysis-of-the-combined-social-phobia-scale-and-social-interaction-anxiety-scale-support-for-a-bifactor-model
#8
Rapson Gomez, Shaun D Watson
For the Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) together, this study examined support for a bifactor model, and also the internal consistency reliability and external validity of the factors in this model. Participants (N = 526) were adults from the general community who completed the SPS and SIAS. Confirmatory factor analysis (CFA) of their ratings indicated good support for the bifactor model. For this model, the loadings for all but six items were higher on the general factor than the specific factors...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28196993/personality-disorders-and-its-association-with-anxiety-and-depression-among-patients-of-severe-acne-a-cross-sectional-study-from-eastern-india
#9
Sharmila Sarkar, Paramita Patra, Kakali Mridha, Sudip Kumar Ghosh, Asish Mukhopadhyay, Rajarshi Guha Thakurta
BACKGROUND: In many patients, emotional stress may exacerbate acne. Psychological problems such as social phobias, low self-esteem, or depression may also occur as a result of acne. The presence of acne may have some negative effect on the quality of life, self-esteem, and mood of the affected patients. While some studies have been undertaken about anxiety, depression, and personality patterns in patients with acne, only a few studies have been done to identify specific personality disorders in patients with acne...
October 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28196739/preschool-needle-pain-responding-establishing-normal
#10
Jordana A Waxman, Miranda G DiLorenzo, Rebecca R Pillai Riddell, David B Flora, Saul Greenberg, Hartley Garfield
The current study sets forth to provide both descriptive data for preschool vaccination pain responding and examine longitudinal relationships over early childhood. Growth mixture modeling (GMM) was first used to describe stable subgroups of preschoolers based on their pain response patterns over 2-minutes post-needle. Secondly, a parallel-process growth curve model was used to assess the stability of acute pain responding from 12-months of age to preschool age. Specifically, we examined whether preschool pain-related distress or regulation could be predicted from 12-month acute pain responding...
February 11, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28173886/comparison-of-the-dsm-5-and-icd-10-panic-and-other-anxiety-disorders
#11
Borwin Bandelow
Anxiety disorders are the most prevalent mental disorders and are associated with substantial healthcare costs and a high burden of disease. In this article, changes in the new Diagnostic and Statistical Manual for Mental Disorders (the DSM-5) with respect to panic disorder/agoraphobia, generalized anxiety disorder, social anxiety disorder, specific phobias, and selective mutism are compared with the International Classification of Diseases (ICD-10) system.
February 8, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28157599/harm-beliefs-and-coping-expectancies-in-youth-with-specific-phobias
#12
Thomas H Ollendick, Lars-Göran Öst, Sarah M Ryan, Nicole N Capriola, Lena Reuterskiöld
Catastrophic beliefs and lowered coping expectancies are often present in individuals with specific phobias (SPs). The current study examined these beliefs and expectancies in 251 youth who received One Session Treatment for one of the three most common types of SP in youth (animals, natural environment, and situational). We compared the children's subjective beliefs to objective ratings of the likelihood of occurrence and the dangerousness of the feared events. Results revealed pre-treatment differences in the youths' beliefs across phobia types and age...
April 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28144878/diverse-profiles-of-anxiety-related-disorders-in-fragile-x-cornelia-de-lange-and-rubinstein-taybi-syndromes
#13
Hayley Crawford, Jane Waite, Chris Oliver
Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein-Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive-compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive-compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive-compulsive subscales...
January 31, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28122091/d-cycloserine-augmentation-of-exposure-based-cognitive-behavior-therapy-for-anxiety-obsessive-compulsive-and-posttraumatic-stress-disorders-a-systematic-review-and-meta-analysis
#14
David Mataix-Cols, Lorena Fernández de la Cruz, Benedetta Monzani, David Rosenfield, Erik Andersson, Ana Pérez-Vigil, Paolo Frumento, Rianne A de Kleine, JoAnn Difede, Boadie W Dunlop, Lara J Farrell, Daniel Geller, Maryrose Gerardi, Adam J Guastella, Stefan G Hofmann, Gert-Jan Hendriks, Matt G Kushner, Francis S Lee, Eric J Lenze, Cheri A Levinson, Harry McConnell, Michael W Otto, Jens Plag, Mark H Pollack, Kerry J Ressler, Thomas L Rodebaugh, Barbara O Rothbaum, Michael S Scheeringa, Anja Siewert-Siegmund, Jasper A J Smits, Eric A Storch, Andreas Ströhle, Candyce D Tart, David F Tolin, Agnes van Minnen, Allison M Waters, Carl F Weems, Sabine Wilhelm, Katarzyna Wyka, Michael Davis, Christian Rück
Importance: Whether and under which conditions D-cycloserine (DCS) augments the effects of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders is unclear. Objective: To clarify whether DCS is superior to placebo in augmenting the effects of cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders and to evaluate whether antidepressants interact with DCS and the effect of potential moderating variables...
January 25, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28114091/-virtual-reality-therapy-in-anxiety-disorders
#15
V Mitrousia, O Giotakos
During the last decade a number of studies have been conducted in order to examine if virtual reality exposure therapy can be an alternative form of therapy for the treatment of mental disorders and particularly for the treatment of anxiety disorders. Imaginal exposure therapy, which is one of the components of Cognitive Behavioral Therapy, cannot be easily applied to all patients and in cases like those virtual reality can be used as an alternative or a supportive psychotherapeutic technique. Most studies using virtual reality have focused on anxiety disorders, mainly in specific phobias, but some extend to other disorders such as eating disorders, drug dependence, pain control and palliative care and rehabilitation...
October 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28100203/diaphragmatic-breathing-during-virtual-reality-exposure-therapy-for-aviophobia-functional-coping-strategy-or-avoidance-behavior-a-pilot-study
#16
Youssef Shiban, Julia Diemer, Jana Müller, Johanna Brütting-Schick, Paul Pauli, Andreas Mühlberger
BACKGROUND: Although there is solid evidence for the efficacy of in vivo and virtual reality (VR) exposure therapy for a specific phobia, there is a significant debate over whether techniques promoting distraction or relaxation have impairing or enhancing effects on treatment outcome. In the present pilot study, we investigated the effect of diaphragmatic breathing (DB) as a relaxation technique during VR exposure treatment. METHOD: Twenty-nine patients with aviophobia were randomly assigned to VR exposure treatment either with or without diaphragmatic breathing (six cycles per minute)...
January 18, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28068460/side-effects-to-antidepressant-treatment-in-patients-with-depression-and-comorbid-panic-disorder
#17
Stewart A Shankman, Stephanie M Gorka, Andrea C Katz, Daniel N Klein, John C Markowitz, Bruce A Arnow, Rachel Manber, Barbara O Rothbaum, Michael E Thase, Alan F Schatzberg, Martin B Keller, Madhukar H Trivedi, James H Kocsis
OBJECTIVE: Side effects to antidepressant medication can affect the efficacy of treatment, but few predictors foretell who experiences side effects and which side effects they experience. This secondary data analysis examined whether depressed patients with comorbid panic disorder were more likely to experience side effects than those without panic disorder. The study also examined whether greater burden of side effects predicted a poorer treatment course for patients with panic disorder than those without panic disorder...
January 3, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28066706/initial-and-sustained-brain-responses-to-threat-anticipation-in-blood-injection-injury-phobia
#18
Leonie Brinkmann, Hendrik Poller, Martin J Herrmann, Wolfgang Miltner, Thomas Straube
Blood-injection-injury (BII) phobia differs from other subtypes of specific phobia in that it is associated with elevated disgust-sensitivity as well as specific autonomic and brain responses during processing of phobia-relevant stimuli. To what extent these features play a role already during threat anticipation is unclear. In the current fMRI experiment, 16 female BII phobics and 16 female healthy controls anticipated the presentation of phobia-specific and neutral pictures. On the behavioral level, anxiety dominated the anticipatory period in BII phobics relative to controls, while both anxiety and disgust were elevated during picture presentation...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28032271/profiles-of-temperament-among-youth-with-specific-phobias-implications-for-cbt-outcomes
#19
Nicole N Capriola, Jordan A Booker, Thomas H Ollendick
Specific phobias (SPs) are characterized by excessive fear or anxiety regarding an object or situation. SPs often result in a host of negative outcomes in childhood and beyond. Children with SPs are broadly assumed to show dispositional over-regulation and fearfulness relative to children without SPs, but there are few attempts to distinguish dispositional patterns among children with SPs. In the present study, we examined trajectories of differing temperamental profiles for youth receiving a CBT-based treatment for their SP...
December 29, 2016: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28030746/association-of-fluid-intelligence-and-psychiatric-disorders-in-a-population-representative-sample-of-us-adolescents
#20
Katherine M Keyes, Jonathan Platt, Alan S Kaufman, Katie A McLaughlin
Importance: Despite long-standing interest in the association of psychiatric disorders with intelligence, few population-based studies of psychiatric disorders have assessed intelligence. Objective: To investigate the association of fluid intelligence with past-year and lifetime psychiatric disorders, disorder age at onset, and disorder severity in a nationally representative sample of US adolescents. Design, Setting, and Participants: National sample of adolescents ascertained from schools and households from the National Comorbidity Survey Replication-Adolescent Supplement, collected 2001 through 2004...
February 1, 2017: JAMA Psychiatry
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