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https://www.readbyqxmd.com/read/29667943/factors-associated-with-initiation-of-biologics-in-patients-with-axial-spondyloarthritis-in-an-urban-asian-city-a-prespond-study
#1
Wan Yu Png, Yu Heng Kwan, Yi Xuan Lee, Ka Keat Lim, Eng Hui Chew, Nai Lee Lui, Chuen Seng Tan, Julian Thumboo, Truls Østbye, Warren Fong
OBJECTIVE: The aim of this study was to examine if patients' sociodemographic, clinical characteristics, and patient-reported outcomes were associated with biologics initiation in patients with axial spondyloarthritis in Singapore. METHODS: Data from a dedicated registry from a tertiary referral center in Singapore from January 2011 to July 2016 were used. Initiation of first biologics was the main outcome of interest. Logistic regression analyses were used to explore the association of various factors on biologics initiation...
April 5, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29667726/interventions-for-infantile-haemangiomas-of-the-skin
#2
REVIEW
Monica Novoa, Eulalia Baselga, Sandra Beltran, Lucia Giraldo, Ali Shahbaz, Hector Pardo-Hernandez, Ingrid Arevalo-Rodriguez
BACKGROUND: Infantile haemangiomas (previously known as strawberry birthmarks) are soft, raised swellings of the skin that occur in 3% to 10% of infants. These benign vascular tumours are usually uncomplicated and tend to regress spontaneously. However, when haemangiomas occur in high-risk areas, such as near the eyes, throat, or nose, impairing their function, or when complications develop, intervention may be necessary. This is an update of a Cochrane Review first published in 2011...
April 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29666029/modern-day-bicruciate-retaining-total-knee-arthroplasty-a-short-term-review-of-146-knees
#3
Omar K Alnachoukati, Roger H Emerson, Elizabeth Diaz, Emily Ruchaud, Kwame A Ennin
BACKGROUND: Bicruciate retaining (BCR) implants were first proposed in the 1960s with the polycentric knee. Given the technical difficulty of implanting these devices, and the mixed results at the time, the BCR concept had stalled, until recently. This study seeks to provide a short-term review of the BCR implant design, describe patient-reported outcomes, and discuss key aspects to ensure successful implantation of the modern-day BCR implant design. METHODS: Between October 2014 and December 2016, the senior author performed 146 primary total knee arthroplasties using BCR implants...
March 17, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29664921/predictors-of-vision-impairment-in-multiple-sclerosis
#4
Bernardo Sanchez-Dalmau, Elena H Martinez-Lapiscina, Irene Pulido-Valdeolivas, Irati Zubizarreta, Sara Llufriu, Yolanda Blanco, Nuria Sola-Valls, Maria Sepulveda, Ana Guerrero, Salut Alba, Magi Andorra, Anna Camos, Laura Sanchez-Vela, Veronica Alfonso, Albert Saiz, Pablo Villoslada
Visual impairment significantly alters the quality of life of people with Multiple Sclerosis (MS). The objective of this study was to identify predictors (independent variables) of visual outcomes, and to define their relationship with neurological disability and retinal atrophy when assessed by optical coherence tomography (OCT). We performed a cross-sectional analysis of 119 consecutive patients with MS, assessing vision using high contrast visual acuity (LogMar), 2.5% and 1.25% low contrast visual acuity (Sloan charts), and color vision (Hardy-Rand-Rittler plates)...
2018: PloS One
https://www.readbyqxmd.com/read/29663629/examination-of-the-relationship-between-disease-activity-and-patient-reported-outcome-measures-in-an-inflammatory-bowel-disease-cohort
#5
Belinda D Jackson, Danny Con, Alexandra Gorelik, Danny Liew, Simon Knowles, Peter De Cruz
BACKGROUND: The extent to which disease activity impacts on patient reported outcomes (PROs) is unclear. AIMS: The purpose of this study was to examine the relationship between disease activity and PROs. METHODS: Adult IBD patients attending a tertiary clinic from May to June 2015 were included. Assessment of disease activity (SCCAI, HBI), IBD knowledge (CCKNOW), medication adherence (MMAS8), psychological distress (HADS), work productivity (WPAI) and quality of life (IBDQ) was performed to investigate any correlations between disease activity and PROs...
April 16, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29663516/a-2-year-prospective-study-of-single-implant-mandibular-overdentures-patient-reported-outcomes-and-prosthodontic-events
#6
Túlio Eduardo Nogueira, Fernanda Maria Oliveira Aguiar, Bento Alves de Barcelos, Cláudio Rodrigues Leles
OBJECTIVE: This prospective clinical trial aimed to assess clinical and patient-reported outcomes of the single-implant mandibular overdenture treatment (SIMO) after a 2-year follow-up period. MATERIALS AND METHODS: An external hexagon implant was inserted in the mandibular midline of 45 complete denture wearers. Participants had a mean age of 63.4 (SD = 8.3), and 75.6% were female. Based on the primary stability of the implant, immediate loading was performed in 38 patients (84...
April 16, 2018: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/29663509/patients-with-a-previous-total-hip-replacement-experience-less-reduction-of-back-pain-following-lumbar-back-surgery
#7
Ted Eneqvist, Erik Bülow, Szilárd Nemes, Helena Brisby, Göran Garellick, Peter Fritzell, Ola Rolfson
The coexistence of degenerative disorders from the hip joint and the lumbar spine, known as "the hip-spine syndrome", is a common encounter in clinical practice. These degenerative conditions may cause similar symptoms which often entail diagnostic challenges in determining the origin of pain. Low back surgery (LBS) with fusion and/or decompression, and total hip replacement (THR) are both often successful interventions. However, the knowledge is limited about the post-operative patient-reported outcome (PRO) following LBS in the presence of a prior THR...
April 16, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29663303/abdominoperineal-resection-for-rectal-cancer-in-the-twenty-first-century-indications-techniques-and-outcomes
#8
Alexander T Hawkins, Katherine Albutt, Paul E Wise, Karim Alavi, Ranjan Sudan, Andreas M Kaiser, Liliana Bordeianou
BACKGROUND: Management of low rectal cancer continues to be a challenge, and decision making regarding the need for an abdominoperineal resection (APR) in patients with low-lying tumors is complicated. Furthermore, choices need to be made regarding need for modification of the surgical approach based on tumor anatomy and patient goals. DISCUSSION: In this article, we address patient selection, preoperative planning, and intraoperative technique required to perform the three types of abdominoperineal resections for rectal cancer: extrasphincteric, extralevator, and intersphincteric...
April 16, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29663258/a-meta-analytic-review-of-measurement-equivalence-study-findings-of-the-sf-36%C3%A2-and-sf-12%C3%A2-health-surveys-across-electronic-modes-compared-to-paper-administration
#9
Michelle K White, Stephen M Maher, Avery A Rizio, Jakob B Bjorner
PURPOSE: Patient-reported outcome (PRO) measures originally developed for paper administration are increasingly being administered electronically in clinical trials and other health research studies. Three published meta-analyses of measurement equivalence among paper and electronic modes aggregated findings across hundreds of PROs, but there has not been a similar meta-analysis that addresses a single PRO, partly because there are not enough published measurement equivalence studies using the same PRO...
April 16, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29663257/validation-of-the-promis-sleep-disturbance-and-sleep-related-impairment-item-banks-in-dutch-adolescents
#10
Jojanneke A M C van Kooten, Raphaёle R L van Litsenburg, Whitney R Yoder, Gertjan J L Kaspers, Caroline B Terwee
PURPOSE: Sleep problems are common in adolescents and have a negative impact on daytime functioning. However, there is a lack of well-validated adolescent sleep questionnaires. The Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance and Sleep-Related Impairment item banks are well-validated instruments developed for and tested in adults. The aim of this study was to evaluate their structural validity in adolescents. METHODS: Test and retest data were collected for the Dutch-Flemish V1...
April 16, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29663137/health-related-quality-of-life-among-cancer-patients-in-their-last-year-of-life-results-from-the-profiles-registry
#11
Natasja J H Raijmakers, M Zijlstra, J van Roij, O Husson, S Oerlemans, L V van de Poll-Franse
PURPOSE: The aim of this study was to assess health-related quality of life (HRQoL) in the last year of life of cancer patients stratified by four periods of time before death. PATIENTS AND METHODS: Between 2008 and 2015, cancer patients were invited to participate in PROFILES (Patient Reported Outcomes Following Initial Treatment and Long-term Evaluation of Survivorship) registry studies. Patients were eligible for inclusion in this secondary analysis if they had been invited to complete the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) in their last year of life (N = 892)...
April 16, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29663077/is-patient-reported-outcome-improved-by-nalfurafine-hydrochloride-in-patients-with-primary-biliary-cholangitis-and-refractory-pruritus-a-post-marketing-single-arm-prospective-study
#12
Minami Yagi, Atsushi Tanaka, Tadashi Namisaki, Atsushi Takahashi, Masanori Abe, Akira Honda, Yasushi Matsuzaki, Hiromasa Ohira, Hitoshi Yoshiji, Hajime Takikawa
BACKGROUND: Patients with primary biliary cholangitis (PBC) frequently suffer from pruritus, which can severely impair their health-related quality of life (HRQOL). Nalfurafine hydrochloride, a selective κ-opioid receptor agonist, was recently approved in Japan for refractory pruritus in patients with chronic liver diseases, but it still remains unclear whether this treatment improves the patient-reported outcome (PRO) in PBC patients with refractory pruritus. Herein, we conducted a multicenter, post-marketing, single-arm prospective study to investigate the efficacy of nalfurafine in terms of PRO, and the associations of the efficacy with any clinical characteristics...
April 16, 2018: Journal of Gastroenterology
https://www.readbyqxmd.com/read/29662912/relationship-between-quantitative-mri-biomarkers-and-patient-reported-outcome-measures-after-cartilage-repair-surgery-a-systematic-review
#13
REVIEW
Drew A Lansdown, Kevin Wang, Eric Cotter, Annabelle Davey, Brian J Cole
Background: Treatment of articular cartilage injuries remains a clinical challenge, and the optimal tools to monitor and predict clinical outcomes are unclear. Quantitative magnetic resonance imaging (qMRI) allows for a noninvasive biochemical evaluation of cartilage and may offer advantages in monitoring outcomes after cartilage repair surgery. Hypothesis: qMRI sequences will correlate with early pain and functional measures. Study Design: Systematic review; Level of evidence, 3...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29662910/outcomes-and-return-to-sport-after-revision-anterior-cruciate-ligament-reconstruction-in-adolescent-athletes
#14
Michael Saper, Stephanie Pearce, Joseph Shung, Robert Zondervan, Roger Ostrander, James R Andrews
Background: The number of adolescent anterior cruciate ligament (ACL) injuries is rising with increased participation in higher level athletics at earlier ages. With an increasing number of primary ACL reconstructions (ACLRs) comes a rise in the incidence of revision ACLRs. Purpose: To evaluate the clinical results of revision ACLR across a group of high-level adolescent athletes with at least 2-year follow-up. Study Design: Case series; Level of evidence, 4...
April 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29662880/common-evaluations-of-disease-activity-in-rheumatoid-arthritis-reach-discordant-classifications-across-different-populations
#15
Helena Canhão, Ana Maria Rodrigues, Maria João Gregório, Sara S Dias, José António Melo Gomes, Maria José Santos, Augusto Faustino, José António Costa, Cornelia Allaart, Emilia Gvozdenović, Desirée van der Heijde, Pedro Machado, Jaime C Branco, João Eurico Fonseca, José António Silva
Objectives: The classification of disease activity states in rheumatoid arthritis (RA) can be achieved through disease activity indices, such as the Disease Activity Score in 28 joints erythrocyte sedimentation rate (DAS28-ESR), the Simplified Disease Activity Index (SDAI), and the Clinical Disease Activity Index (CDAI). Subjective measurements, such as patient reported outcomes have been incorporated into several of these indices alongside more objective assessments, such as increases in the ESR and C-reactive protein...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29662746/the-predictive-value-of-preoperative-health-related-quality-of-life-scores-on-postoperative-patient-reported-outcome-scores-in-lumbar-spine-surgery
#16
Hwee Weng Dennis Hey, Nan Luo, Sze Yung Chin, Eugene Tze Chun Lau, Pei Wang, Naresh Kumar, Leok-Lim Lau, John Nathaniel Ruiz, Joseph Shanthakumar Thambiah, Ka-Po Gabriel Liu, Hee-Kit Wong
Study Design: A single-center, retrospective cohort study. Objective: To predict patient-reported outcomes (PROs) using preoperative health-related quality-of-life (HRQoL) scores by quantifying the correlation between them, so as to aid selection of surgical candidates and preoperative counselling. Methods: All patients who underwent single-level elective lumbar spine surgery over a 2-year period were divided into 3 diagnosis groups: spondylolisthesis, spinal stenosis, and disc herniation...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29662722/acupuncture-for-chronic-pain-in-the-vermont-medicaid-population-a-prospective-pragmatic-intervention-trial
#17
Robert T Davis, Gary Badger, Kristina Valentine, Alexander Cavert, Remy R Coeytaux
Introduction: In response to the opioid crisis, the 2016 Vermont legislature commissioned a study to assess acupuncture for patients with chronic pain in the Vermont Medicaid population. Objective: To assess the feasibility, acceptability, and effectiveness of acupuncture provided by licensed acupuncturists for Vermont Medicaid patients with chronic pain. Methods: A total of 156 Medicaid patients with chronic pain were offered up to 12 acupuncture treatments within a 60-day period at the offices of 28 Vermont licensed acupuncturists...
2018: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
https://www.readbyqxmd.com/read/29661814/psychometric-findings-and-normative-values-for-the-cleft-q-based-on-2434-children-and-young-adult-patients-with-cleft-lip-and-or-palate-from-12-countries
#18
Anne F Klassen, Karen Wy Wong Riff, Natasha M Longmire, Asteria Albert, Gregory C Allen, Mustafa Asim Aydin, Stephen B Baker, Stefan J Cano, Andrew J Chan, Douglas J Courtemanche, Marieke M Dreise, Jesse A Goldstein, Timothy E E Goodacre, Karen E Harman, Montserrat Munill, Aisling O Mahony, Mirta Palomares Aguilera, Petra Peterson, Andrea L Pusic, Rona Slator, Mia Stiernman, Elena Tsangaris, Sunil S Tholpady, Federico Vargas, Christopher R Forrest
BACKGROUND: Patients with cleft lip and/or palate can undergo numerous procedures to improve appearance, speech, dentition and hearing. We developed a cleft-specific patient-reported outcome instrument to facilitate rigorous international measurement and benchmarking. METHODS: Data were collected from patients aged 8-29 years with cleft lip and/or palate at 30 hospitals in 12 countries between October 2014 and November 2016. Rasch measurement theory analysis was used to refine the scales and to examine reliability and validity...
April 16, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/29661025/self-efficacy-as-a-predictor-of-patient-reported-outcomes-in-adults-with-congenital-heart-disease
#19
Corina Thomet, Philip Moons, Markus Schwerzmann, Silke Apers, Koen Luyckx, Erwin N Oechslin, Adrienne H Kovacs
OBJECTIVE: Self-efficacy is a known predictor of patient-reported outcomes in individuals with acquired diseases. With an overall objective of better understanding patient-reported outcomes in adults with congenital heart disease, this study aimed to: (i) assess self-efficacy in adults with congenital heart disease, (ii) explore potential demographic and medical correlates of self-efficacy and (iii) determine whether self-efficacy explains additional variance in patient-reported outcomes above and beyond known predictors...
April 1, 2018: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/29660795/symptom-and-function-profiles-of-men-with-localized-prostate-cancer
#20
Bryce B Reeve, Xianming Tan, Ronald C Chen, Deborah S Usinger, Laura C Pinheiro
BACKGROUND: Men diagnosed with localized prostate cancer seek information on how treatment options may impact their health-related quality of life (HRQOL). The authors used latent profile analysis (LPA) to group men according to their symptom burden and functional status and to identify patient characteristics associated with each HRQOL profile. METHODS: Patients completed the Patient-Reported Outcomes Measurement Information System and the Expanded Prostate Index Composite measures 3 months after treatment initiation...
April 16, 2018: Cancer
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