keyword
MENU ▼
Read by QxMD icon Read
search

Reproductive health

keyword
https://www.readbyqxmd.com/read/30247637/janus-kinase-jak1-maintains-the-ovarian-reserve-of-primordial-follicles-in-the-mouse-ovary
#1
Jessie M Sutherland, Emily R Frost, Emmalee A Ford, Alexandra E Peters, Natalie L Reed, Alexandra N Seldon, Bettina P Mihalas, Darryl L Russel, Kylie R Dunning, Eileen A McLaughlin
STUDY QUESTION: Is the Janus kinase and signal transducer and activator of transcription (JAK-STAT) signalling pathway involved in ovarian follicle development and primordial follicle activation? SUMMARY ANSWER: JAK1 is a key factor involved in the regulation of primordial follicle activation and maintenance of the ovarian reserve. WHAT IS KNOWN ALREADY: A series of integrated, intrinsic signalling pathways (including PI3K/AKT, mTOR and KITL) are responsible for regulating the ovarian reserve of non-growing primordial follicles and ultimately female fertility...
September 24, 2018: Molecular Human Reproduction
https://www.readbyqxmd.com/read/30247365/acog-committee-opinion-no-756-optimizing-support-for-breastfeeding-as-part-of-obstetric-practice
#2
(no author information available yet)
As reproductive health experts and advocates for women's health who work in conjunction with other obstetric and pediatric health care providers, obstetrician-gynecologists are uniquely positioned to enable women to achieve their infant feeding goals. Maternity care policies and practices that support breastfeeding are improving nationally; however, more work is needed to ensure all women receive optimal breastfeeding support during prenatal care, during their maternity stay, and after the birth occurs. Enabling women to breastfeed is a public health priority because, on a population level, interruption of lactation is associated with adverse health outcomes for the woman and her child, including higher maternal risks of breast cancer, ovarian cancer, diabetes, hypertension, and heart disease, and greater infant risks of infectious disease, sudden infant death syndrome, and metabolic disease...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30247364/acog-committee-opinion-no-755-well-woman-visit
#3
(no author information available yet)
A well-woman visit provides an excellent opportunity to counsel patients about maintaining a healthy lifestyle and minimizing health risks. Given the shifting and complex landscape of care, in which many women may not receive all the recommended preventive services, obstetrician-gynecologists have an opportunity to contribute to the overall health and well-being of women throughout the lifespan by providing recommended preventive services and counseling. Taking a comprehensive history (specifically obtaining detailed information on symptoms and past medical and gynecologic history) will inform if certain components of the physical examination, including breast or pelvic examination, are indicated at that visit and will inform shared decision making for these examinations...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30247363/acog-committee-opinion-no-754-the-utility-of-and-indications-for-routine-pelvic-examination
#4
(no author information available yet)
The pelvic examination has long been considered a fundamental component of the well-woman visit, and many women and gynecologic care providers view this visit as an opportunity to discuss sexual and reproductive health issues. Traditionally, a pelvic examination is performed for asymptomatic women as a screening tool for gynecologic cancer, infection, and asymptomatic pelvic inflammatory disease; some obstetrician-gynecologists and patients consider it important in detecting subclinical disease, despite evidence to the contrary...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30247361/acog-committee-opinion-no-756-summary-optimizing-support-for-breastfeeding-as-part-of-obstetric-practice
#5
(no author information available yet)
As reproductive health experts and advocates for women's health who work in conjunction with other obstetric and pediatric health care providers, obstetrician-gynecologists are uniquely positioned to enable women to achieve their infant feeding goals. Maternity care policies and practices that support breastfeeding are improving nationally; however, more work is needed to ensure all women receive optimal breastfeeding support during prenatal care, during their maternity stay, and after the birth occurs. Enabling women to breastfeed is a public health priority because, on a population level, interruption of lactation is associated with adverse health outcomes for the woman and her child, including higher maternal risks of breast cancer, ovarian cancer, diabetes, hypertension, and heart disease, and greater infant risks of infectious disease, sudden infant death syndrome, and metabolic disease...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30247360/acog-committee-opinion-no-755-summary-well-woman-visit
#6
(no author information available yet)
A well-woman visit provides an excellent opportunity to counsel patients about maintaining a healthy lifestyle and minimizing health risks. Given the shifting and complex landscape of care, in which many women may not receive all the recommended preventive services, obstetrician-gynecologists have an opportunity to contribute to the overall health and well-being of women throughout the lifespan by providing recommended preventive services and counseling. Taking a comprehensive history (specifically obtaining detailed information on symptoms and past medical and gynecologic history) will inform if certain components of the physical examination, including breast or pelvic examination, are indicated at that visit and will inform shared decision making for these examinations...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30247359/acog-committee-opinion-no-754-summary-the-utility-of-and-indications-for-routine-pelvic-examination
#7
(no author information available yet)
The pelvic examination has long been considered a fundamental component of the well-woman visit, and many women and gynecologic care providers view this visit as an opportunity to discuss sexual and reproductive health issues. Traditionally, a pelvic examination is performed for asymptomatic women as a screening tool for gynecologic cancer, infection, and asymptomatic pelvic inflammatory disease; some obstetrician-gynecologists and patients consider it important in detecting subclinical disease, despite evidence to the contrary...
October 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/30246020/modulation-of-diabetes-mellitus-induced-male-rat-reproductive-dysfunction-with-micro-nanoencapsulated-echinacea-purpurea-ethanol-extract
#8
Chien-Feng Mao, Xiu-Ru Zhang, Athira Johnson, Jia-Ling He, Zwe-Ling Kong
Diabetes mellitus is a major health problem that affects a patient's life quality throughout the world due to its worst complications. It was recognized that chronic hyperglycemia with oxidative stress was the major cause of male infertility. Echinacea purpurea ethanol extract (EE) contains phenolic acid and isobutylamides had been proven to ameliorate diabetic complications. Chitosan/silica nanoparticles are well-known in the medicinal field because of its controlled release and drug delivery properties. This study was aimed at investigating whether the EE encapsulated chitosan/silica nanoparticle (nano-EE) can enhance the amelioration of male infertility...
2018: BioMed Research International
https://www.readbyqxmd.com/read/30245866/integration-of-hiv-and-reproductive-health-services-in-public-sector-facilities-analysis-of-client-flow-data-over-time-in-kenya
#9
Isolde J Birdthistle, Justin Fenty, Martine Collumbien, Charlotte Warren, James Kimani, Charity Ndwiga, Susannah Mayhew
Introduction: Integration of HIV/AIDS with reproductive health (RH) services can increase the uptake and efficiency of services, but gaps in knowledge remain about the practice of integration, particularly how provision can be expanded and performance enhanced. We assessed the extent and nature of service integration in public sector facilities in four districts in Kenya. Methods: Between 2009 and 2012, client flow assessments were conducted at six time points in 24 government facilities, purposively selected as intervention or comparison sites...
2018: BMJ Global Health
https://www.readbyqxmd.com/read/30245516/the-evolving-landscape-of-expanded-carrier-screening-challenges-and-opportunities
#10
REVIEW
Stephanie A Kraft, Devan Duenas, Benjamin S Wilfond, Katrina A B Goddard
Carrier screening allows individuals to learn their chance of passing on an autosomal or X-linked condition to their offspring. Initially introduced as single-disease, ancestry-based screening, technological advances now allow for the possibility of multi-disease, pan-ethnic carrier screening, which we refer to as "expanded carrier screening." There are numerous potential benefits to expanded carrier screening, including maximizing the opportunity for couples to make autonomous reproductive decisions, and efficiency and marginal additional costs of including more conditions if the test is already being offered...
September 24, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/30245359/urinary-excretion-of-phenols-parabens-and-benzophenones-in-young-men-associations-to-reproductive-hormones-and-semen-quality-are-modified-by-mutations-in-the-filaggrin-gene
#11
Ulla Nordström Joensen, Niels Jørgensen, Jacob P Thyssen, Pal Bela Szecsi, Steen Stender, Jørgen Holm Petersen, Anna-Maria Andersson, Hanne Frederiksen
BACKGROUND: The filaggrin gene (FLG) encodes an epidermal protein, filaggrin, which is important for normal skin barrier functions. We previously showed that FLG loss-of-function mutation carriers have a higher internal exposure to some non-persistent chemicals such as certain phthalates and parabens, suggesting increased trans-epidermal penetration. Several groups of non-persistent chemicals are suspected endocrine disrupters with potential to affect testicular function. OBJECTIVES: To investigate associations between exposure to non-persistent chemicals and testicular function in young Danish men with and without FLG mutations...
September 20, 2018: Environment International
https://www.readbyqxmd.com/read/30245028/an-ancient-fecundability-associated-polymorphism-creates-a-gata2-binding-site-in-a-distal-enhancer-of-hla-f
#12
Katelyn M Mika, Xilong Li, Francesco J DeMayo, Vincent J Lynch
Variation in female reproductive traits, such as fertility, fecundity, and fecundability, are heritable in humans, but identifying and functionally characterizing genetic variants associated with these traits have been challenging. Here, we explore the functional significance and evolutionary history of a G/A polymorphism at SNP rs2523393, which is an eQTL for HLA-F and is significantly associated with fecundability (the probability of being pregnant within a single menstrual cycle). We replicated the association between the rs2523393 genotype and HLA-F expression by using GTEx data and demonstrate that HLA-F is upregulated in the endometrium during the window of implantation and by progesterone in decidual stromal cells...
September 13, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/30244672/gendered-norms-of-responsibility-reflections-on-accountability-politics-in-maternal-health-care-in-malawi
#13
Elsbet Lodenstein, Kyra Pedersen, Kondwani Botha, Jacqueline E W Broerse, Marjolein Dieleman
BACKGROUND: This paper aims to provide insights into the role of traditional authorities in two maternal health programmes in Northern Malawi. Among strategies to improve maternal health, these authorities issue by-laws: local rules to increase the uptake of antenatal and delivery care. The study uses a framework of gendered institutions to critically assess the by-law content, process and effects and to understand how responsibilities and accountabilities are constructed, negotiated and reversed...
September 24, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/30244291/comparing-fertility-preservation-resources-and-policies-between-nccn-member-and-non-member-institutions
#14
Meghan Bowman-Curci, Gwendolyn P Quinn, Joyce Reinecke, Richard R Reich, Susan T Vadaparampil
PURPOSE: The National Comprehensive Cancer Network (NCCN) created guidelines to facilitate implementation of fertility preservation (FP) discussions and referrals for adolescent and young adult patients. We assessed if availability of workplace FP resources and referral policies differed among learners in the Educating Nurses about Reproductive Health in Cancer Healthcare (ENRICH) training program based on NCCN membership. METHODS: Learners completed a baseline application, including demographic information and the availability of FP resources and referral policies...
September 22, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/30242634/control-strategies-in-multigroup-models-the-case-of-the-star-network-topology
#15
Fernando Saldaña, Ignacio Barradas
In this paper, we propose control strategies for multigroup epidemic models. We use compartmental [Formula: see text] models to study the dynamics of n host groups sharing the same source of infection in addition to the transmission among members of the same group. In particular, we consider a model for infectious diseases with free-living pathogens in the environment and a metapopulation model with a central patch. We give the detailed derivation of the target reproduction number under three public health interventions and provide the corresponding biological insights...
September 21, 2018: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/30241473/gastroesophageal-reflux-disease-and-its-related-factors-among-women-of-reproductive-age-korea-nurses-health-study
#16
Oksoo Kim, Hee Jung Jang, Sue Kim, Hea-Young Lee, Eunyoung Cho, Jung Eun Lee, Heeja Jung, Jiyoung Kim
BACKGROUND: Recently, the number of patients diagnosed with gastroesophageal reflux disease (GERD) has increased in Korea. Risk factors of GERD include age, sex, medication use, lack of physical exercise, increased psychological stress, low or high body mass index (BMI), unhealthy eating habits, increased alcohol consumption, and cigarette smoking. However, few studies examined the major factors affecting GERD in women of childbearing age. Therefore, this study assessed the risk factors of GERD among 20,613 female nurses of reproductive age using data from the Korea Nurses' Health Study...
September 21, 2018: BMC Public Health
https://www.readbyqxmd.com/read/30241236/understanding-men-s-perceptions-of-human-papillomavirus-and-cervical-cancer-screening-in-kampala-uganda
#17
Erin Moses, Heather N Pedersen, Emily C Wagner, Musa Sekikubo, Deborah M Money, Gina S Ogilvie, Sheona M Mitchell-Foster
PURPOSE: This preliminary study explores Ugandan men's knowledge and attitudes about human papillomavirus (HPV), cervical cancer, and screening. METHODS: A local physician led an education session about cervical cancer for 62 men in Kisenyi, Kampala in Uganda. Trained nurse midwives administered surveys to assess knowledge and attitudes before and after the education session. RESULTS: From the pre-education survey, only 24.6% of men had heard of HPV previously, and 59% of men had heard of cervical cancer...
September 2018: Journal of Global Oncology
https://www.readbyqxmd.com/read/30240830/a-hypothesis-driven-weight-of-evidence-analysis-to-evaluate-potential-endocrine-activity-of-perfluorohexanoic-acid
#18
S J Borghoff, S Fitch, J E Rager, D Huggett
Perfluorohexanoic acid (PFHxA) is a potential impurity and environmental degradation product of C6-based fluorotelomer products. Considering the potential endocrine activity of perfluoroalkyl acids, a hypothesis-driven weight-of-evidence (WoE) analysis was conducted to evaluate the potential endocrine disruptor activity of PFHxA, as defined by World Health Organization (WHO), across estrogen (E), androgen (A), thyroid (T), and steroidogenesis (S) pathways. A comprehensive literature search identified primary and secondary studies across species for review...
September 18, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/30239785/homozygous-in-frame-deletion-in-catspere-in-a-man-producing-spermatozoa-with-loss-of-catsper-function-and-compromised-fertilizing-capacity
#19
Sean G Brown, Melissa R Miller, Polina V Lishko, Douglas H Lester, Stephen J Publicover, Christopher L R Barratt, Sarah Martins Da Silva
STUDY QUESTION: Does a man (patient 1) with a previously described deficiency in principle cation channel of sperm (CatSper) function have a mutation in the CatSper-epsilon (CATSPERE) and/or CatSper-zeta (CATSPERZ) gene? SUMMARY ANSWER: Patient 1 has a homozygous in-frame 6-bp deletion in exon 18 (c.2393_2398delCTATGG, rs761237686) of CATSPERE. WHAT IS KNOWN ALREADY: CatSper is the principal calcium channel of mammalian spermatozoa. Spermatozoa from patient 1 had a specific loss of CatSper function and were unable to fertilize at IVF...
October 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30239732/endometriosis-and-adverse-maternal-fetal-and-neonatal-outcomes-a-systematic-review-and-meta-analysis
#20
S Lalani, A J Choudhry, B Firth, V Bacal, Mark Walker, S W Wen, S Singh, A Amath, M Hodge, I Chen
STUDY QUESTION: How is endometriosis associated with adverse maternal, fetal and neonatal outcomes of pregnancy? SUMMARY ANSWER: Women with endometriosis are at elevated risk for serious and important adverse maternal (pre-eclampsia, gestational diabetes, placenta praevia and Cesarean section) and fetal or neonatal outcomes (preterm birth, PPROM, small for gestational age, stillbirth and neonatal death). WHAT IS KNOWN ALREADY: A number of studies have shown an association between endometriosis and certain adverse maternal and fetal outcomes, but the results have been conflicting with potential for confounding by the use of assisted reproductive technology...
September 17, 2018: Human Reproduction
keyword
keyword
1014
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"