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https://www.readbyqxmd.com/read/28915967/the-concept-of-protective-nerve-stimulation-for-ultrasound-guided-nerve-blocks
#1
Martin Ertmer, Edda Klotz, Jürgen Birnbaum
Regional plexus and nerve blocks are a common technique in modern anesthesia. Since ultrasound machines are available in many departments, the role of nerve stimulation is highly discussed and different approaches to perform the blocks are taken into account. Common technique for electrical nerve stimulation is searching for a stimulating threshold of 0.4-0.5mA using an impulse width of 0.1ms. We present our hypothesis of using all possible information with a new concept of protective nerve stimulation together with first data supporting our theory...
September 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28894986/fertility-intentions-pregnancy-and-use-of-prep-and-art-for-safer-conception-among-east-african-hiv-serodiscordant-couples
#2
Renee Heffron, Kerry Thomson, Connie Celum, Jessica Haberer, Kenneth Ngure, Nelly Mugo, Elizabeth Bukusi, Elly Katabira, Josephine Odoyo, Nulu Bulya, Stephen Asiimwe, Edna Tindimwebwa, Jared M Baeten
African HIV serodiscordant couples often desire pregnancy, despite sexual HIV transmission risk during pregnancy attempts. Pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) reduce HIV risk and can be leveraged for safer conception but how well these strategies are used for safer conception is not known. We conducted an open-label demonstration project of the integrated delivery of PrEP and ART among 1013 HIV serodiscordant couples from Kenya and Uganda followed quarterly for 2 years. We evaluated fertility intentions, pregnancy incidence, the use of PrEP and ART during peri-conception, and peri-conception HIV incidence...
September 11, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28885043/negotiating-the-edge-the-rationalization-of-sexual-risk-taking-among-western-male-sex-tourists-to-thailand
#3
Simon Bishop, Mark Limmer
Every year thousands of Western men travel to Thailand as sex tourists to participate in paid-for sex. Although many of these men will use condoms to protect themselves against sexually transmitted infections (STIs), others will not, despite the risks. By applying Steven Lyng's (1990) concept of edgework to data collected from 14 face-to-face interviews with male sex tourists in Pattaya, Thailand, and 1,237 online discussion board posts, this article explores the ways in which these men understood and sought to rationalize the sexual risks they took...
September 8, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28880892/beyond-hiv-serodiscordance-partnership-communication-dynamics-that-affect-engagement-in-safer-conception-care
#4
Lynn T Matthews, Bridget F Burns, Francis Bajunirwe, Jerome Kabakyenga, Mwebesa Bwana, Courtney Ng, Jasmine Kastner, Annet Kembabazi, Naomi Sanyu, Adrine Kusasira, Jessica E Haberer, David R Bangsberg, Angela Kaida
INTRODUCTION: We explored acceptability and feasibility of safer conception methods among HIV-affected couples in Uganda. METHODS: We recruited HIV-positive men and women on antiretroviral therapy (ART) ('index') from the Uganda Antiretroviral Rural Treatment Outcomes cohort who reported an HIV-negative or unknown-serostatus partner ('partner'), HIV-serostatus disclosure to partner, and personal or partner desire for a child within two years. We conducted in-depth interviews with 40 individuals from 20 couples, using a narrative approach with tailored images to assess acceptability of five safer conception strategies: ART for the infected partner, pre-exposure prophylaxis (PrEP) for the uninfected partner, condomless sex timed to peak fertility, manual insemination, and male circumcision...
2017: PloS One
https://www.readbyqxmd.com/read/28836240/-recognition-of-specialization-of-minimally-invasive-treatment-for-gastric-cancer-in-the-era-of-precision-medicine
#5
Heng Zhang, Jiangyong Sang, Fenglin Liu
With the introduction and promotion of "precision medicine" conception, the history of disease occurrence, progression and prognosis has been deeply investigated with more accuracy, and the surgical treatment concept has become more precise and minimally invasive. With the rapid development of minimally invasive technique, laparoscopic gastrectomy has become an important part for treatment of gastric cancer. A number of randomized controlled clinical trials, such as KLASS-01 and CLASS-01, have demonstrated that laparoscopic gastrectomy is safe and feasible for treatment of early and locally advanced gastric cancer, respectively...
August 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28829720/optimizing-prevention-of-hiv-and-unplanned-pregnancy-in-discordant-african-couples
#6
Kristin M Wall, William Kilembe, Bellington Vwalika, Lisa B Haddad, Naw Htee Khu, Ilene Brill, Udodirim Onwubiko, Elwyn Chomba, Amanda Tichacek, Susan Allen
BACKGROUND: Dual method use, which combines condoms with a more effective modern contraceptive to optimize prevention of HIV and unplanned pregnancy, is underutilized in high-risk heterosexual couples. MATERIALS AND METHODS: Heterosexual HIV-discordant Zambian couples were enrolled from couples' voluntary HIV counseling and testing services into an open cohort with 3-monthly follow-up (1994-2012). Relative to dual method use, defined as consistent condom use plus modern contraception, we examine predictors of (1) condom-only use (suboptimal pregnancy prevention) or (2) modern contraceptive use with inconsistent condom use (effective pregnancy prevention and suboptimal HIV prevention)...
August 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28825897/hiv-care-providers-communication-with-patients-about-safer-conception-for-people-living-with-hiv-in-tanzania
#7
Haneefa T Saleem, Pamela J Surkan, Deanna Kerrigan, Caitlin E Kennedy
CONTEXT: People living with HIV may desire children, but often lack information about safer conception and pregnancy and face barriers to obtaining high-quality reproductive health services. To inform clinical guidance that supports HIV-affected couples wanting to conceive, it is important to better understand communication between patients and providers about childbearing and safer-conception guidelines for people living with HIV. METHODS: In-depth interviews were conducted with 30 providers of HIV-related services in seven health facilities in Iringa, Tanzania, and with 60 HIV-positive women and men attending study facilities...
December 1, 2016: International Perspectives on Sexual and Reproductive Health
https://www.readbyqxmd.com/read/28814235/nanotechnology-in-neurosciences-an-approach
#8
Rosa Helena Bustos, M Magdy Sánchez, Maria Andrea Dominguez, George E Barreto, Daniel Lancheros, Jorge Reynolds
The use of nanotechnology in neurosciences has been evolving since new treatments, diagnoses and biomolecule monitoring are needed to find safer treatments for central nervous system diseases (CNDs). Nanotechnology employs devices that interact with biological systems allowing molecular interactions with a high degree of specificity. This review considers concepts associated with nanotechnology and leading areas of neurosciences with nanotechnology research.
August 15, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28782316/rediscovering-chirality-role-of-s-metoprolol-in-cardiovascular-disease-management
#9
Jagdish C Mohan, Siddharth N Shah, Sunny Chinchansurkar, Arindam Dey, Rishi Jain
BACKGROUND: The process of drug discovery and development today encompass a myriad of paths for bringing a new therapeutic molecule that has minimal adverse effects and of optimal use to the patient. Chirality was proposed in the direction of providing a purer and safer form of drug [Ex- cetrizine and levocetrizine]. Decades have passed since the introduction of this concept and numerous chiral molecules are in existence in therapeutics, yet somehow this concept has been ignored. This review aims to rediscover the ignored facts about chirality, its benefits and clear some common myths considering the example of S-Metoprolol in the management of Hypertension and other cardiovascular diseases...
June 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28737672/mesoporous-silica-nanoparticles-as-drug-delivery-vehicles-in-cancer
#10
REVIEW
Anna Watermann, Juergen Brieger
Even though cancer treatment has improved over the recent decades, still more specific and effective treatment concepts are mandatory. Surgical removal is not always possible, metastases are challenging and chemo- and radiotherapy can not only have severe side-effects but also resistances may occur. To cope with these challenges more efficient therapies with fewer side-effects are required. One promising approach is the use of drug delivery vehicles. Here, mesoporous silica nanoparticles (MSN) are discussed as biodegradable drug carrier to improve efficacy and reduce side-effects...
July 22, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28726042/reproductive-desires-and-considerations-of-hiv-positive-men-in-heterosexual-relationships-in-new-york-city
#11
Karolynn Siegel, Étienne Meunier, Jack Ume Tocco, Helen-Maria Lekas
The reproductive desires of HIV-positive men have been investigated far less than those of HIV-positive women, especially in the US. This qualitative study of a sample of 94 HIV-positive men in New York City who were in a relationship with a woman of reproductive age examined their reasons for wanting a child as well as the conditions under which they would feel ready to attempt conception. Participants felt a child would make them feel normal, give meaning to their lives, or make others in their life happy...
July 19, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28719614/beat-id-towards-a-computationally-low-cost-single-heartbeat-biometric-identity-check-system-based-on-electrocardiogram-wave-morphology
#12
Joana S Paiva, Duarte Dias, João P S Cunha
In recent years, safer and more reliable biometric methods have been developed. Apart from the need for enhanced security, the media and entertainment sectors have also been applying biometrics in the emerging market of user-adaptable objects/systems to make these systems more user-friendly. However, the complexity of some state-of-the-art biometric systems (e.g., iris recognition) or their high false rejection rate (e.g., fingerprint recognition) is neither compatible with the simple hardware architecture required by reduced-size devices nor the new trend of implementing smart objects within the dynamic market of the Internet of Things (IoT)...
2017: PloS One
https://www.readbyqxmd.com/read/28719229/experiences-using-pre-exposure-prophylaxis-for-safer-conception-among-hiv-serodiscordant-heterosexual-couples-in-the-united-states
#13
Angela R Bazzi, Ashley A Leech, Dea L Biancarelli, Meg Sullivan, Mari-Lynn Drainoni
Antiretroviral pre-exposure prophylaxis (PrEP) is a promising HIV prevention strategy for HIV serodiscordant couples (HIV-infected male, uninfected female) seeking safer conception. However, most research on PrEP for safer conception has focused on couples in sub-Saharan Africa; little is known about the perspectives or experiences of heterosexual couples in the United States. We conducted qualitative interviews with six couples (six women and five of their male partners) receiving PrEP for conception services at an urban safety net hospital in the US Northeast...
August 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28716376/improving-the-safety-of-health-information-technology-requires-shared-responsibility-it-is-time-we-all-step-up
#14
Dean F Sittig, Elisabeth Belmont, Hardeep Singh
In 2011, an Institute of Medicine report on health information technology (IT) and patient safety highlighted that building health-IT for safer use is a shared responsibility between key stakeholders including: "vendors, care providers, healthcare organizations, health-IT departments, and public and private agencies". Use of electronic health records (EHRs) involves all these stakeholders, but they often have conflicting priorities and requirements. Since 2011, the concept of shared responsibility has gained little traction and EHR developers and users continue to attribute the substantial, long list of problems to each other...
July 14, 2017: Healthcare
https://www.readbyqxmd.com/read/28709752/safer-conception-and-contraceptive-counseling-by-providers-of-men-living-with-hiv-in-san-francisco
#15
Megan Orlando, Shannon Weber, Rebecca Martinez, Deborah Cohan, Dominika Seidman
No abstract text is available yet for this article.
June 19, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/28691575/performance-power-and-condom-use-reconceptualised-masculinities-amongst-western-male-sex-tourists-to-thailand
#16
Simon Bishop, Mark Limmer
Each year large numbers of Western men travel to Thailand for sex tourism. Although many will use condoms during their sexual encounters, others will not, potentially exposing themselves to the risk of acquiring sexually transmitted infections, including HIV. Although sex tourism in Thailand has been well documented, the social drivers underpinning voluntary sexual risk-taking through the avoidance of condoms remain poorly understood. Engaging with R.W. Connell's concept of hegemonic masculinity and drawing on data collected from 1237 online discussion board posts and 14 face-to-face interviews, this study considers the ways in which understandings and performances of masculinities may inform the sexual risk-taking behaviours of Western male sex tourists...
July 10, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28677200/the-nature-of-the-therapeutic-alliance-between-nurses-and-consumers-with-anorexia-nervosa-in-the-inpatient-setting-a%C3%A2-mixed-methods-study
#17
Joel S Zugai, Jane Stein-Parbury, Michael Roche
AIMS AND OBJECTIVES: To develop a greater understanding of the nature of the inpatient therapeutic alliance between nurses and consumers with Anorexia Nervosa (AN). BACKGROUND: Consumers with AN value interpersonal relationships with nurses, finding these relationships meaningful and therapeutic. It is established that the therapeutic alliance enhances outcomes for consumers with AN. However, establishing the therapeutic alliance in the inpatient setting is considered challenging...
July 5, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28669837/the-microbiological-mind-project-a-public-engagement-initiative-of-turin-university-bringing-microbiology-and-health-education-into-primary-schools
#18
Daniela Scalas, Janira Roana, Narcisa Mandras, Sonia Cuccu, Giuliana Banche, Elisa Simona Marra, Nicoletta Collino, Giorgia Piersigilli, Valeria Allizond, Vivian Tullio, Anna Maria Cuffini
Despite ongoing global efforts, antimicrobial resistance continues to threaten the treatment of an ever-increasing range of bacterial infections. Substantial evidence has shown that public education programs that foster microbial literacy amongst young school audiences may improve correct knowledge of specific health issues, such as prevention of microbial infections and responsible use of antibiotics. The aim of the Microbiological@mind project was to engage primary school students with the subject of microbiology, to promote both scientific interest and awareness towards correct behaviors that may ensure a safer lifestyle...
June 29, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28598742/a-call-to-action-the-controversy-of-and-rationale-for-competency-based-medical-education
#19
Eric S Holmboe, Jonathan Sherbino, Robert Englander, Linda Snell, Jason R Frank
Although medical education has enjoyed many successes over the last century, there is a recognition that health care is too often unsafe and of poor quality. Errors in diagnosis and treatment, communication breakdowns, poor care coordination, inappropriate use of tests and procedures, and dysfunctional collaboration harm patients and families around the world. These issues reflect on our current model of medical education and raise the question: Are physicians being adequately prepared for twenty-first century practice? Multiple reports have concluded the answer is "no...
June 2017: Medical Teacher
https://www.readbyqxmd.com/read/28597343/safer-conception-for-couples-affected-by-hiv-structural-and-cultural-considerations-in-the-delivery-of-safer-conception-care-in-uganda
#20
Deborah Mindry, Rhoda K Wanyenze, Jolly Beyeza-Kashesya, Mahlet A Woldetsadik, Sarah Finocchario-Kessler, Kathy Goggin, Glenn Wagner
In countries with high HIV prevalence and high fertility desires, the rights of HIV-affected couples to have children are a pressing issue. Conception among people living with HIV carries risks for both horizontal and vertical HIV transmission. In Uganda ~100,000 HIV-infected women become pregnant annually. Providers face a number of challenges to preventing HIV transmission, reducing unplanned pregnancies, and ensuring safer conception. We report findings from interviews with 27 HIV-affected couples (54 individuals) in Uganda...
June 8, 2017: AIDS and Behavior
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