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https://www.readbyqxmd.com/read/28922100/frequency-and-antibiotic-resistance-of-bacteria-implicated-in-community-urinary-tract-infections-in-north-aveiro-between-2011-and-2014
#1
Tânia Costa, Inês Linhares, Ricardo Ferreira, Jasmin Neves, Adelaide Almeida
AIMS: The present study aims to evaluate the predominance of uropathogens responsible for urinary tract infection (UTI) and determine their resistance patterns, to assess if the recommended empirical treatment is appropriate for the studied population. Samples were collected in Aveiro (Portugal) from an ambulatory service between June 2011 and June 2014. RESULTS: From the 4,270 positive urine samples for UTI, 3,561 (83%) were from women and only 709 (17%) were from men...
September 18, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28919055/antimicrobial-resistance-in-women-with-urinary-tract-infection-in-primary-care-no-relation-with-type-2-diabetes-mellitus
#2
Johanna E M Vinken, Helen E Mol, Theo J M Verheij, Sanne van Delft, Marion Kolader, Miquel B Ekkelenkamp, Guy E H M Rutten, Berna D L Broekhuizen
AIMS: To determine if type 2 diabetes mellitus (T2DM) is associated with the spectrum of uropathogens and antimicrobial resistance in urinary tract infections (UTI) in primary care. METHODS: A cross-sectional study in female outpatients ≥30 years with positive urine cultures. T2DM patients were 1:1 matched to controls by age group and general practitioner (GP). GPs were sent questionnaires for additional data. Uropathogens and resistance patterns were compared between patients with and without T2DM...
September 14, 2017: Primary Care Diabetes
https://www.readbyqxmd.com/read/28910943/-study-on-antibiotic-resistance-of-escherichia-coli-and-enterococcus-colonized-in-intestine-of-neonates-from-neonatal-intensive-care-unit
#3
X F Li, Z J Liu, X Chen, J Li, Z G Cui, B Kan, J R Ma, J H Cui
Objective: To understand the antibiotic resistance of bacteria colonized in intestine of the neonates from neonatal intensive care unit (NICU) and provide evidence to guide clinical antibiotic treatment. Methods: From May, 2014 to May, 2015, a total of 572 stool samples were collected from the neonates of NICU in our hospital. Escherichia coli and Enterococcus were detected with VITEK-2 system. Results: A total of 328 strains of E. coli and 243 strains of Enterococcus were isolated respectively in this study...
September 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28882177/ampc-and-extended-spectrum-beta-lactamases-production-among-urinary-isolates-from-a-tertiary-care-hospital-in-lalitpur-nepal
#4
Suman Rai, Narayan Dutt Pant, Raju Bhandari, Anil Giri, Roshan Parajuli, Manoj Aryal, Jyoti Amatya, Vijay Kumar Sharma
BACKGROUND: Production of AmpC and extended spectrum beta-lactamases among urinary isolates has created a serious problem to the successful management of the urinary tract infection. The main purpose of this study was to determine the rates of the extended spectrum beta-lactamase (ESBL) production and AmpC beta-lactamase (ABL) production among urinary isolates. RESULTS: Among total 564 urinary isolates, 514 (91.1%) were gram negative bacilli and 50 (8.9%) were gram positive cocci...
September 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28840351/activity-of-temocillin-and-15-other-agents-including-fosfomycin-and-colistin-against-enterobacteriaceae-in-hong-kong
#5
Margaret Ip, Christopher K Lai, Kitty S C Fung, K-Tak Wong, Chendi Zhu, Sebastien Van de Velde, Dominic N Tsang, Peter Hawkey
Limited data are available on temocillin susceptibilities in Enterobacteriaceae from Asian countries where antimicrobial resistance is prevalent. The in vitro activities of temocillin and 15 commonly used antimicrobials against 613 non-duplicate blood (n = 310) and urine (with clinically significant bacteriuria; n = 303) isolates of Enterobacteriaceae from patients who attended 3 out of 7 clusters of public hospitals of the Hospital Authority, Hong Kong, during 2015/2016 were tested. Minimum inhibitory concentrations (MICs) were determined by Clinical and Laboratory Standards Institute (CLSI) microbroth dilution (agar dilution with fosfomycin)...
August 25, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28832488/committee-opinion-no-717-sulfonamides-nitrofurantoin-and-risk-of-birth-defects
#6
(no author information available yet)
The evidence regarding an association between the nitrofuran and sulfonamide classes of antibiotics and birth defects is mixed. As with all patients, antibiotics should be prescribed for pregnant women only for appropriate indications and for the shortest effective duration. During the second and third trimesters, sulfonamides and nitrofurantoins may continue to be used as first-line agents for the treatment and prevention of urinary tract infections and other infections caused by susceptible organisms. Prescribing sulfonamides or nitrofurantoin in the first trimester is still considered appropriate when no other suitable alternative antibiotics are available...
September 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28832479/committee-opinion-no-717-summary-sulfonamides-nitrofurantoin-and-risk-of-birth-defects
#7
(no author information available yet)
The evidence regarding an association between the nitrofuran and sulfonamide classes of antibiotics and birth defects is mixed. As with all patients, antibiotics should be prescribed for pregnant women only for appropriate indications and for the shortest effective duration. During the second and third trimesters, sulfonamides and nitrofurantoins may continue to be used as first-line agents for the treatment and prevention of urinary tract infections and other infections caused by susceptible organisms. Prescribing sulfonamides or nitrofurantoin in the first trimester is still considered appropriate when no other suitable alternative antibiotics are available...
September 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28825574/-etiology-and-antimicrobial-resistance-of-uncomplicated-urinary-tract-infections
#8
Guillermo Bertoni, Pedro Pessacq, María Graciela Guerrini, Aníbal Calmaggi, Fernanda Barberis, Laura Jorge, Pablo Bonvehi, Elena Temporiti, Fabián Herrera, Mora Obed, Belén Alcorta, Juan Farías, Analía Mykietiuk
Uncomplicated urinary tract infections rank among the most frequent bacterial infections in women in the outpatient setting and represent a major cause of antimicrobial prescription. The aims of this study were to assess frequencies and antimicrobial resistance of current uropathogens causing uncomplicated urinary tract infection. In a prospective multicenter study, patients were recruited in ambulatory settings of four participating hospitals between June 2011 and December 2013. We analyzed 138 patients that met clinical and bacteriological diagnostic criteria...
2017: Medicina
https://www.readbyqxmd.com/read/28819490/maternofetal-outcome-of-asymptomatic-bacteriuria-among-pregnant-women-in-a-nigerian-teaching-hospital
#9
Kenneth Ebele Izuchukwu, Emmanuel Okwudili Oranu, Goddy Bassey, Ngozi Clare Orazulike
INTRODUCTION: Asymptomatic bacteriuria has been reported to be associated with adverse pregnancy outcome. This study sought to determine the prevalence and complications of asymptomatic bacteriuria amongst parturient in the University of Port Harcourt Teaching Hospital (UPTH). METHODS: The study was a prospective cohort study involving 220 eligible antenatal attendees. Urine culture and sensitivity was conducted for each participant and the fetomaternal outcome between affected and unaffected women were compared and p value <0...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28818593/nitrofurantoin-hydrolytic-degradation-in-the-environment
#10
Martina Biošić, Irena Škorić, Jasmina Beganović, Sandra Babić
Occurrence of pharmaceuticals, especially antibiotics in the environment increased attention to their environmental fate. Hydrolysis is one of two abiotic processes by which compounds are degraded in the environment. According to authors knowledge this is the first study investigating hydrolytic degradation of nitrofurantoin at pH-values normally found in the environment. Nitrofurantoin hydrolytic degradation appeared to be much slower at acidic (pH 4) solution compared to neutral (pH 7) and alkaline (pH 9) solutions at all three investigated temperatures (20 °C, 40 °C and 60 °C)...
November 2017: Chemosphere
https://www.readbyqxmd.com/read/28792540/antibiotics-resistance-in-el-tor-vibrio-cholerae-01-isolated-during-cholera-outbreaks-in-mozambique-from-2012-to-2015
#11
Liliana Candida Dengo-Baloi, Cynthia Amino Semá-Baltazar, Lena Vania Manhique, Jucunu Elias Chitio, Dorteia Luísa Inguane, José Paulo Langa
RATIONALE: Mozambique has recorded cyclically epidemic outbreaks of cholera. Antibiotic therapy is recommended in specific situations for management and control of cholera outbreaks. However, an increase in resistance rates to antibiotics by Vibrio cholerae has been reported in several epidemic outbreaks worldwide. On the other hand, there are few recent records of continuous surveillance of antibiotics susceptibility pattern of V. cholerae in Mozambique. GOALS: The purpose of this study was to evaluate antibiotics resistance pattern of Vibrio cholerae O1 Ogawa isolated during Cholera outbreaks in Mozambique to commonly used antibiotics...
2017: PloS One
https://www.readbyqxmd.com/read/28764160/revisiting-nitrofurantoin-for-vancomycin-resistant-enterococci
#12
Suneeta Meena, Sarita Mohapatra, Seema Sood, Benu Dhawan, Bimal Ku Das, Arti Kapil
INTRODUCTION: Enterococcal infection has emerged as a major therapeutic challenge. Emergence of High Level Aminoglycoside Resistance (HLAR) and Vancomycin-Resistant Enterococcus (VRE) has further limited the drug therapy in enterococcal infections. However, nitrofuratoin being an old drug reported to have less resistance in comparison to the other classes of antimicrobial agents. AIM: To detect susceptibility of nitrofurantoin against VRE isolates from Urinary Tract Infection (UTI) of outdoor and indoor patient departments...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28749780/the-prevalence-of-extended-spectrum-beta-lactamase-producing-multidrug-resistant-escherichia-coli-in-poultry-chickens-and-variation-according-to-farming-practices-in-punjab-india
#13
Charles H Brower, Siddhartha Mandal, Shivdeep Hayer, Mandeep Sran, Asima Zehra, Sunny J Patel, Ravneet Kaur, Leena Chatterjee, Savita Mishra, B R Das, Parminder Singh, Randhir Singh, J P S Gill, Ramanan Laxminarayan
BACKGROUND: Agricultural use of antimicrobials in subtherapeutic concentrations is increasing in response to the rising demand for food animal products worldwide. In India, the use of antimicrobials in food animal production is unregulated. Research suggests that many clinically important antimicrobials are used indiscriminately. This is the largest study to date in India that surveys poultry production to test for antimicrobial resistance and the occurrence of extended-spectrum (ESBLs) modulated by farming and managerial practices...
July 20, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28749329/in-vitro-efficacy-of-16-antimicrobial-drugs-against-a-large-collection-of-%C3%AE-lactamase-producing-isolates-of-extraintestinal-pathogenic-escherichia-coli-from-dogs-and-cats
#14
Takae Shimizu, Kazuki Harada, Yuzo Tsuyuki, Yui Kimura, Tadashi Miyamoto, Shingo Hatoya, Yoshiaki Hikasa
PURPOSE: The aim of this study was to assess the in vitro efficacy of candidate antimicrobials against extended-spectrum β-lactamase (ESBL)-producing isolates of extraintestinal pathogenic Escherichia coli (ExPEC) from companion animals. METHODOLOGY: A total of 90 ESBL-producing ExPEC isolates from dogs and cats were tested for susceptibility to 16 antimicrobials with the agar dilution method. We also identified the ESBLs and AmpC β-lactamases of these isolates with PCR and DNA sequencing...
August 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28745297/foley-catheters-functionalised-with-a-synergistic-combination-of-antibiotics-and-silver-nanoparticles-resist-biofilm-formation
#15
Rajendran Mala, Antony Annie Aglin, Arul Selvaraj Ruby Celsia, Sivalingam Geerthika, Narbahvi Kiruthika, Chinnathambi VazagaPriya, Kumarapillai Srinivasa Kumar
Foley catheters are inevitable in health care unit. Pathogens colonise and form biofilm on catheter causing catheter-associated urinary tract infection. Therefore, the authors aimed to functionalise catheter to resist biofilm formation. The authors impregnated urinary catheters with a synergistic combination of antibiotics and silver nanoparticles (SNPs) to evaluate antibiofilm efficacy in vitro and in vivo. SNPs were synthesised using Spirulina platensis. Synergy between the SNPs and antibiotics was determined by the checker-board method...
August 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28743651/resistance-to-quinolones-cephalosporins-and-macrolides-in-escherichia-coli-causing-bacteremia-in-peruvian-children
#16
Noemí Palma, Maria J Pons, Cláudia Gomes, Judit Mateu, Maribel Riveros, Wilfredo García, Jan Jacobs, Coralith García, Theresa J Ochoa, Joaquim Ruiz
OBJECTIVE: To characterize the β-lactam, quinolone and macrolide resistance levels and mechanisms in 62 Escherichia coli isolates causing children bacteremia. METHODS: Minimal inhibitory concentration of ciprofloxacin, nalidixic acid (NAL) and azithromycin was determined in presence and absence of Phe-Arg-β-Naphtylamyde. Additionally, the susceptibility levels to other 14 antimicrobial agents was established. Extended Spectrum β-lactamases (ESBLs) were identified, while mutations in gyrA and parC genes, presence of transferable mechanisms of quinolone-resistance (TMQR) and macrolide-resistance (TMMR) was also determined...
July 22, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/28742000/high-prevalence-of-multidrug-resistant-escherichia-coli-isolates-from-children-with-and-without-diarrhoea-and-their-susceptibility-to-the-antibacterial-activity-of-extracts-fractions-of-fruits-native-to-mexico
#17
Magdalena de Jesús Uribe-Beltrán, Yesmi Patricia Ahumada-Santos, Sylvia Páz Díaz-Camacho, Carlos Alberto Eslava-Campos, Jesús Ernesto Reyes-Valenzuela, María Elena Báez-Flores, Ignacio Osuna-Ramírez, Francisco Delgado-Vargas
PURPOSE: This paper aims to evaluate the antimicrobial resistance of Esherichia coli isolates from children under 5 years old, with and without diarrhoea, who were hospital outpatients in Culiacan, Sinaloa, Mexico. It also looks at the antimicrobial activity of fruit extracts against selected multidrug-resistant (MDR) E. coli strains. METHODOLOGY: A total of 205 E. coli isolates from stool samples were collected from 94 children under 5 years old who were outpatients from two hospitals in the city of Culiacan, Sinaloa, Mexico, during the autumn/winter of 2003/04; their resistance profiles to 19 commercial antimicrobials were investigated using the Kirby-Bauer method...
July 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28738638/mixed-matrix-membranes-incorporated-with-ln-mof-for-selective-and-sensitive-detection-of-nitrofuran-antibiotics-based-on-inner-filter-effect
#18
Feng Zhang, Hua Yao, Yifan Zhao, Xing Li, Gaowei Zhang, Yangyi Yang
The detection of antibiotics is critical and challenging due to the pervasive use of antibiotics had inevitably brought some negative impacts on ecosystem and human health. Herein, we reported an anti-interfere ability enhanced luminescent sensor of lanthanide metal-organic framework (Ln-MOF) filled mixed matrix membranes (MMMs), which combining the processibility of poly(methyl methacrylate) (PMMA) polymer with Ln-MOF of {[Tb2(AIP)2(H2O)10]·(AIP)·4H2O}n (Tb-AIP, where AIP is 5-aminoisophthalate) fillers...
November 1, 2017: Talanta
https://www.readbyqxmd.com/read/28731324/using-infrared-spectroscopy-and-multivariate-analysis-to-detect-antibiotics-resistant-escherichia-coli-bacteria
#19
Uraib Sharaha, Eladio Rodriguez-Diaz, Klaris Riesenberg, Irving J Bigio, Mahmoud Huleihel, Ahmad Salman
Bacterial pathogens are one of the primary causes of human morbidity worldwide. Historically, antibiotics have been highly effective against most bacterial pathogens; however, the increasing resistance of bacteria to a broad spectrum of commonly used antibiotics has become a global health-care problem. Early and rapid determination of bacterial susceptibility to antibiotics has become essential in many clinical settings and, sometimes, can save lives. Currently classical procedures require at least 48 h for determining bacterial susceptibility, which can constitute a life-threatening delay for effective treatment...
September 5, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28722171/use-of-antibiotics-during-pregnancy-and-the-risk-of-major-congenital-malformations-a-population-based-cohort-study
#20
Flory T Muanda, Odile Sheehy, Anick Bérard
INTRODUCTION: Few studies have investigated the link between individual antibiotics and major congenital malformations (MCMs) including specific malformations owing to small sample size. We aimed to quantify the association between exposure to gestational antibiotic and the risk of MCMs. METHODS: Using the Quebec pregnancy cohort (1998 -2008), we included a total of 139,938 liveborn singleton alive whose mothers were covered by the «Régie de l'assurance maladie du Québec" drug plan for at least 12 months before and during pregnancy...
July 19, 2017: British Journal of Clinical Pharmacology
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