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https://www.readbyqxmd.com/read/28821223/maternal-nutrient-restriction-in-mid-to-late-gestation-influences-fetal-mrna-expression-in-muscle-tissues-in-beef-cattle
#1
Francois Paradis, Katie M Wood, Kendall C Swanson, Stephen P Miller, Brian W McBride, Carolyn Fitzsimmons
BACKGROUND: Manipulating maternal nutrition during specific periods of gestation can result in re-programming of fetal and post-natal development. In this experiment we investigated how a feed restriction of 85% compared with 140% of total metabolizable energy requirements, fed to cows during mid-to-late gestation, influences phenotypic development of fetuses and mRNA expression of growth (Insulin-Like Growth Factor family and Insulin Receptor (INSR)), myogenic (Myogenic Differentiation 1 (MYOD1), Myogenin (MYOG), Myocyte Enhancer Factor 2A (MEF2A), Serum Response Factor (SRF)) and adipogenic (Peroxisome Proliferator Activated Receptor Gamma (PPARG)) genes in fetal longissimus dorsi (LD) and semitendinosus (ST) muscle...
August 18, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28803343/sediment-lipid-biomarkers-record-phytoplankton-dynamics-of-lake-heihai-yunnan-province-sw-china-driven-by-climate-warming-since-the-1980s
#2
Yongdong Zhang, Yaling Su, Zhengwen Liu, Jinlei Yu, Miao Jin
Increased phosphorus (P) export from sediments to the overlying water column is a significant factor driving the variation of phytoplankton in productivity and community structure in lakes. However, the lack of long-term instrumental data often impeded analyses attempting to associate dynamics of phytoplankton with variation of internal P loading. Here, elements and lipid biomarkers were analyzed in a sediment core from Lake Heihai, a small, deep, and ultraoligotrophic alpine lake in Haba Mountain, Yunnan Province, SW China...
August 12, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28790874/lack-of-change-in-glucose-metabolism-in-eszopiclone-treated-primary-insomnia-patients
#3
Orfeu M Buxton, Milena K Pavlova, Shawn P O'Connor, Wei Wang, John W Winkelman
STUDY OBJECTIVES: Primary insomnia (PI) may increase diabetes risk. We tested the hypothesis that the effects of PI on glucose metabolism could be improved by 2 months of pharmacological treatment. METHODS: Adult men and women meeting clinical criteria for PI were studied (n=20, body mass index 25.1±2.7 kg/m(2), age 39.7±7.9) in a randomized, double-blind, placebo-controlled clinical trial. The study consisted of two 1-day inpatient admissions to a General Clinical Research Center separated by 2 months of at-home treatment with 3 mg eszopiclone or placebo...
2017: Nature and Science of Sleep
https://www.readbyqxmd.com/read/28771169/effects-of-metal-micro-and-nano-particles-on-hascs-an-in-vitro-model
#4
Silvia Palombella, Cristina Pirrone, Federica Rossi, Ilaria Armenia, Mario Cherubino, Luigi Valdatta, Mario Raspanti, Giovanni Bernardini, Rosalba Gornati
As the knowledge about the interferences of nanomaterials on human staminal cells are scarce and contradictory, we undertook a comparative multidisciplinary study based on the size effect of zero-valent iron, cobalt, and nickel microparticles (MPs) and nanoparticles (NPs) using human adipose stem cells (hASCs) as a model, and evaluating cytotoxicity, morphology, cellular uptake, and gene expression. Our results suggested that the medium did not influence the cell sensitivity but, surprisingly, the iron microparticles (FeMPs) resulted in being toxic...
August 3, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28763102/resistance-to-hydrogen-peroxide-highlights-gymnodinium-catenatum-dinophyceae-sensitivity-to-geomagnetic-activity
#5
Paulo Vale
The chain-forming dinoflagellate Gymnodinium catenatum was exposed to hydrogen peroxide. Microscopical examination revealed striking dose-response alterations in chain formation above 245 μM: singlets replaced the dominance of long chain formations. These observations were valid for cells acclimated to halogen light. Under fluorescent light, cells were more resistant to modifications in chain length after H2 O2 exposure. Growth along 9-hour in the presence of extracelular H2 O2 followed an hormesis response in both light regimes...
August 1, 2017: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/28735384/influence-of-feeding-inorganic-vanadium-on-growth-performance-endocrine-variables-and-biomarkers-of-bone-health-in-crossbred-calves
#6
Ravi Prakash Pal, Veena Mani, Deepika Tripathi, Rajesh Kumar, Neelam J Kewalramani
The nutritional essentialities of transition element vanadium (V) as micro-nutrient in farm animals have not yet been established, though in rat model, vanadium as vanadate has been reported to exert insulin-mimetic effect and shown to be needed for proper development of bones. The objective of this study was to determine the effect of V supplementation on growth performance, plasma hormones and bone health status in calves. Twenty-four crossbred calves (body weight 72.83 ± 2.5 kg; age 3-9 months) were blocked in four groups and randomly assigned to four treatment groups (n = 6) on body weight and age basis...
July 22, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28725934/-scaffold-based-bone-tissue-engineering
#7
REVIEW
B M Holzapfel, M Rudert, D W Hutmacher
Tissue engineering provides the possibility of regenerating damaged or lost osseous structures without the need for permanent implants. Within this context, biodegradable and bioresorbable scaffolds can provide structural and biomechanical stability until the body's own tissue can take over their function. Additive biomanufacturing makes it possible to design the scaffold's architectural characteristics to specifically guide tissue formation and regeneration. Its nano-, micro-, and macro-architectural properties can be tailored to ensure vascularization, oxygenation, nutrient supply, waste exchange, and eventually ossification not only in its periphery but also in its center, which is not in direct contact with osteogenic elements of the surrounding healthy tissue...
August 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28715420/blood-vessel-tortuosity-selects-against-evolution-of-aggressive-tumor-cells-in-confined-tissue-environments-a-modeling-approach
#8
András Szabó, Roeland M H Merks
Cancer is a disease of cellular regulation, often initiated by genetic mutation within cells, and leading to a heterogeneous cell population within tissues. In the competition for nutrients and growth space within the tumors the phenotype of each cell determines its success. Selection in this process is imposed by both the microenvironment (neighboring cells, extracellular matrix, and diffusing substances), and the whole of the organism through for example the blood supply. In this view, the development of tumor cells is in close interaction with their increasingly changing environment: the more cells can change, the more their environment will change...
July 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28714408/biomaterials-and-supercritical-fluid-technologies-which-perspectives-to-fabricate-artificial-extracellular-matrix
#9
Della Porta Giovanna, E Reverchon, N Maffulli
The foundation of tissue engineering for either therapeutic or diagnostic applications is the ability to exploit living cells. Tissue engineering utilizes living cells as engineering materials implanted, seeded or bio-plotted into an artificial structure capable of supporting three-dimensional tissue formation. These structures, typically called scaffolds, are critical, both ex vivo and in vivo, to influence their own microenvironments. Scaffolds can serve the following purposes: allow cell attachment and migration, deliver and retain cells and biochemical factors, enable diffusion of vital cell nutrients or expressed products, exert certain mechanical and biological influences to modify the behaviour of the cell phase...
July 13, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28709220/three-dimensional-mechanisms-of-macro-to-micro-scale-transport-and-absorption-enhancement-by-gut-villi-motions
#10
Yanxing Wang, James G Brasseur
We evaluate the potential for physiological control of intestinal absorption by the generation of "micromixing layers" (MMLs) induced by coordinated motions of mucosal villi coupled with lumen-scale "macro" eddying motions generated by gut motility. To this end, we apply a three-dimensional (3D) multigrid lattice-Boltzmann model of a lid-driven macroscale cavity flow with microscale fingerlike protuberances at the lower surface. Integrated with a previous 2D study of leaflike villi, we generalize to 3D the 2D mechanisms found there to enhance nutrient absorption by controlled villi motility...
June 2017: Physical Review. E
https://www.readbyqxmd.com/read/28709055/declining-atmospheric-deposition-of-heavy-metals-over-the-last-three-decades-is-reflected-in-soil-and-foliage-of-97-beech-fagus-sylvatica-stands-in-the-vienna-woods
#11
Selina Türtscher, Pétra Berger, Leopold Lindebner, Torsten W Berger
Rigorous studies on long-term changes of heavy metal distribution in forest soils since the implementation of emission controls are rare. Hence, we resampled 97 old-growth beech stands in the Vienna Woods. This study exploits an extensive data set of soil (infiltration zone of stemflow and between trees area) and foliar chemistry from three decades ago. It was hypothesized that declining deposition of heavy metals is reflected in soil and foliar total contents of Pb, Cu, Zn, Ni, Mn and Fe. Mean soil contents of Pb in the stemflow area declined at the highest rate from 223 to 50 mg kg(-1) within the last three decades...
July 11, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28708055/prion-disease-pathogenesis-in-the-absence-of-the-commensal-microbiota
#12
Barry M Bradford, Laura Tetlow, Neil A Mabbott
Prion diseases are a unique group of transmissible, typically sub-acute, neurodegenerative disorders. During central nervous system (CNS) prion disease, the microglia become activated and are thought to provide a protective response by scavenging and clearing prions. The mammalian intestine is host to a large burden of commensal micro-organisms, especially bacteria, termed the microbiota. The commensal microbiota has beneficial effects on host health, including through the metabolism of essential nutrients, regulation of host development and protection against pathogens...
July 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28697569/relationships-of-dietary-patterns-foods-and-micro-and-macronutrients-with-alzheimer-s-disease-and-late-life-cognitive-disorders-a-systematic-review
#13
Vincenzo Solfrizzi, Carlo Custodero, Madia Lozupone, Bruno P Imbimbo, Vincenzo Valiani, Pasquale Agosti, Andrea Schilardi, Alessia D'Introno, Maddalena La Montagna, Mariapaola Calvani, Vito Guerra, Rodolfo Sardone, Daniela I Abbrescia, Antonello Bellomo, Antonio Greco, Antonio Daniele, Davide Seripa, Giancarlo Logroscino, Carlo Sabbá, Francesco Panza
In the last decade, the association between diet and cognitive function or dementia has been largely investigated. In the present article, we systematically reviewed observational studies published in the last three years (2014-2016) on the relationship among dietary factors and late-life cognitive disorders at different levels of investigation (i.e., dietary patterns, foods and food-groups, and dietary micro- and macronutrients), and possible underlying mechanisms of the proposed associations. From the reviewed evidence, the National Institute on Aging-Alzheimer's Association guidelines for Alzheimer's disease (AD) and cognitive decline due to AD pathology introduced some evidence suggesting a direct relation between diet and changes in the brain structure and activity...
2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28693950/enhanced-volatile-fatty-acids-production-from-anaerobic-fermentation-of-food-waste-a-mini-review-focusing-on-acidogenic-metabolic-pathways
#14
REVIEW
Miaomiao Zhou, Binghua Yan, Jonathan W C Wong, Yang Zhang
Recently, efficient disposal of food waste (FW) with potential resource recovery has attracted great attentions. Due to its easily biodegradable nature, rich nutrient availability and high moisture content, FW is regarded as favorable substrate for anaerobic digestion (AD). Both waste disposal and energy recovery can be fulfilled during AD of FW. Volatile fatty acids (VFAs) which are the products of the first-two stages of AD, are widely applied in chemical industry as platform chemicals recently. Concentration and distribution of VFAs is the result of acidogenic metabolic pathways, which can be affected by the micro-environment (e...
June 26, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28686606/plant-fed-versus-chemicals-fed-rhizobacteria-of-lucerne-plant-only-teabags-culture-media-not-only-increase-culturability-of-rhizobacteria-but-also-recover-a-previously-uncultured-lysobacter-sp-novosphingobium-sp-and-pedobacter-sp
#15
Nabil A Hegazi, Mohamed S Sarhan, Mohamed Fayez, Sascha Patz, Brian R Murphy, Silke Ruppel
In an effort to axenically culture the previously uncultivable populations of the rhizobacteria of Lucerne (Medicago sativa L.), we propose plant-only teabags culture media to mimic the nutritional matrix available in the rhizosphere. Here, we show that culture media prepared from Lucerne powder teabags substantially increased the cultivability of Lucerne rhizobacteria compared with a standard nutrient agar, where we found that the cultivable populations significantly increased by up to 60% of the total bacterial numbers as estimated by Quantitative Real-time Polymerase Chain Reaction (qRT-PCR)...
2017: PloS One
https://www.readbyqxmd.com/read/28686043/the-role-of-nutrition-in-the-pathophysiology-and-management-of-sickle-cell-disease-among-children-a-review-of-literature
#16
Agartha Ohemeng, Isaac Boadu
Sickle cell disease (SCD) is one of the common inherited blood disorders in humans and has been associated with decreased dietary intake which results in poor nutritional status and impaired growth. Nutrition is one of the most important but often forgotten aspect of care of patients with chronic disorders and there have been emerging concern in literature on increased nutritional needs of SCD patients. This paper sought to review the available literature on the roles of individual nutrients in the pathophysiology and management of SCD among children...
July 7, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28681690/development-of-nutrient-rich-growing-media-with-hazelnut-husk-and-municipal-sewage-sludge
#17
Omer Hulusi Dede, Saim Ozdemir
In the present study, development of structurally stable, rich in nutrients and environmentally safe growing media was carried out by combining waste material: crop residue hazelnut husk and municipal sewage sludge. In order to achieve this goal, structurally stable lignocellulosic hazelnut husk (HH) residue was mixed with nutrient-rich sewage sludge (S) in various proportions: HH 100%; HH+S1 87.5% : 12.5%; HH+S2 75% : 2 5%; HH+S3 50% : 5 0%. Following composting, the key physical, chemical and microbiological properties of the growing media were characterized for long term ornamental nursery crops...
July 6, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28680370/effects-of-a-combined-protein-and-antioxidant-supplement-on-recovery-of-muscle-function-and-soreness-following-eccentric-exercise
#18
Stephen J Ives, Samuel Bloom, Alexs Matias, Noelle Morrow, Natalya Martins, Yookee Roh, Daniel Ebenstein, Gabriel O'Brien, Daniela Escudero, Kevin Brito, Leah Glickman, Scott Connelly, Paul J Arciero
BACKGROUND: An acute bout of eccentric contractions (ECC) cause muscle fiber damage, inflammation, impaired muscle function (MF) and muscle soreness (MS). Individually, protein (PRO) and antioxidant (AO) supplementation may improve some aspects of recovery from ECC, though have yet to be combined. We sought to determine if combined PRO and AO supplementation (PRO + AO) improves MS and MF following damaging ECC over PRO alone. METHODS: Sixty sedentary college-aged males participated in a randomized, single-blind, parallel design study of peak isometric torque (PIMT), peak isokinetic torque (PIKT), thigh circumference (TC), and muscle soreness (MS) of knee extensor muscles measured at baseline, immediately after and 1, 2, 6, and 24 h after completion of 100 maximal ECC...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28649070/elemental-analysis-of-ten-plant-species-at-three-phenological-stages
#19
Musharaf Khan, Farrukh Hussain, Farid Ullah Khan, Shahana Musharaf, - Imdadullah
Livestock rearing is a common practice in Tehsil Takht-e-Nasrati by the locals to earn their livelihood. Low productivity due to poor health of livestock is major consideration in the study area. In order to know whether this low productivity and poor health might be due to poor quality of forage, ten plant species were analyzed for micro mineral quantification at three phenological stages. Mineral compositions of plants are used to diagnose probable deficiencies in food and forage and nutritional status of plants...
March 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28646438/noctiluca-and-copepods-grazing-on-the-phytoplankton-community-in-a-nutrient-enriched-coastal-environment-along-the-southwest-coast-of-india
#20
N Arunpandi, R Jyothibabu, L Jagadeesan, T R Gireeshkumar, C Karnan, S W A Naqvi
The relative grazing impact of Noctiluca scintillans (hereafter referred only Noctiluca) and copepods (Acrocalanus gracilis, Paracalanus parvus, Acartia danae and Oithona similis) on the phytoplankton community in an upwelling-mudbank environment along the southwest coast India is presented here. This study was carried out during the Pre-Southwest Monsoon (April-May) to the Late Southwest Monsoon (August) period in 2014. During the sampling period, large hydrographical transformation was evident in the study area (off Alappuzha, Southwest coast of India); warmer Pre-Southwest Monsoon water column condition got transformed into cooler and nitrate-rich hypoxic waters during the Southwest Monsoon (June-August) due to intense coastal upwelling...
July 2017: Environmental Monitoring and Assessment
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