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Integrated surveillance response

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https://www.readbyqxmd.com/read/28525710/mercury-telluride-quantum-dot-based-phototransistor-enabling-high-sensitivity-room-temperature-photodetection-at-2000-nanometers
#1
Mengyu Chen, Haipeng Lu, Nema M Abdelazim, Ye Zhu, Zhen Wang, Wei Ren, Stephen V Kershaw, Andrey L Rogach, Ni Zhao
Near-to-Mid infrared photodetection technologies could be widely deployed to advance the infrastructures of surveillance, environmental monitoring and manufacturing, if the detection devices would be low-cost, in compact format and with high performance. For such application requirements, colloidal quantum dot (QD) based photodetectors stand out as particularly promising due to the solution processability and ease of integration with silicon technologies; unfortunately, the detectivity of the QD photodetectors towards longer wavelengths has so far been low...
May 19, 2017: ACS Nano
https://www.readbyqxmd.com/read/28502807/augmenting-brain-metabolism-to-increase-macro-and-chaperone-mediated-autophagy-for-decreasing-neuronal-proteotoxicity-and-aging
#2
REVIEW
Ben Loos, Daniel J Klionsky, Esther Wong
Accumulation of toxic protein aggregates in the nerve cells is a hallmark of neuronal diseases and brain aging. Mechanisms to enhance neuronal surveillance to improve neuronal proteostasis have a direct impact on promoting neuronal health and forestalling age-related decline in brain function. Autophagy is a lysosomal degradative pathway pivotal for neuronal protein quality control. Different types of autophagic mechanisms participate in protein handling in neurons. Macroautophagy targets misfolded and aggregated proteins in autophagic vesicles to the lysosomes for destruction, while chaperone-mediated autophagy (CMA) degrades specific soluble cytosolic proteins delivered to the lysosomes by chaperones...
May 11, 2017: Progress in Neurobiology
https://www.readbyqxmd.com/read/28492123/factors-associated-with-contracting-malaria-in-ward-29-of-shamva-district-zimbabwe-2014
#3
Gladwin Muchena, Notion Gombe, Lucia Takundwa, Mufuta Tshimanga, Donewell Bangure, Nyasha Masuka, Tsitsi Juru
BACKGROUND: Malaria cases at Wadzanayi Clinic in Shamva District, Zimbabwe, increased drastically, surpassing the epidemic threshold, in week four of December 2013. This rise was sustained, which necessitated an investigation of the outbreak. OBJECTIVES: To identify risk factors and system weaknesses to improve epidemic preparedness and response. METHODS: An unmatched 1:1 case-control study was conducted in Ward 29 of Shamva District in Zimbabwe...
April 25, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28488999/immunisation-information-systems-useful-tools-for-monitoring-vaccination-programmes-in-eu-eea-countries-2016
#4
Tarik Derrough, Kate Olsson, Vincenza Gianfredi, Francois Simondon, Harald Heijbel, Niklas Danielsson, Piotr Kramarz, Lucia Pastore-Celentano
Immunisation Information Systems (IIS) are computerised confidential population based-systems containing individual-level information on vaccines received in a given area. They benefit individuals directly by ensuring vaccination according to the schedule and they provide information to vaccine providers and public health authorities responsible for the delivery and monitoring of an immunisation programme. In 2016, the European Centre for Disease Prevention and Control (ECDC) conducted a survey on the level of implementation and functionalities of IIS in 30 European Union/European Economic Area (EU/EEA) countries...
April 27, 2017: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/28478826/novel-aspects-of-defensins-involvement-in-virus-induced-autoimmunity-in-the-central-nervous-system
#5
Evangelos I Kazakos, Jannis Kountouras, Stergios A Polyzos, Georgia Deretzi
Recent research on re-circulation of interstitial fluid from the brain parenchyma to the periphery and its inferred importance in immune surveillance dysregulation are changing our conceptualization of the pathophysiology of virus-induced autoimmunity. In this context, it is necessary to reassess the immunomodulatory properties of human defensins that are variably expressed by cerebral microglia, astrocytes and choroid plexus epithelial cells and exhibit complex and often confounding roles in neuroinflammatory processes...
May 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/28473308/sa%C3%A3%C2%BAde-na-copa-the-world-s-first-application-of-participatory-surveillance-for-a-mass-gathering-at-fifa-world-cup-2014-brazil
#6
Onicio Leal Neto, George Santiago Dimech, Marlo Libel, Wayner Vieira de Souza, Eduarda Cesse, Mark Smolinski, Wanderson Oliveira, Jones Albuquerque
BACKGROUND: The 2005 International Health Regulations (IHRs) established parameters for event assessments and notifications that may constitute public health emergencies of international concern. These requirements and parameters opened up space for the use of nonofficial mechanisms (such as websites, blogs, and social networks) and technological improvements of communication that can streamline the detection, monitoring, and response to health problems, and thus reduce damage caused by these problems...
May 4, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28469889/a-quality-improvement-approach-to-standardization-and-sustainability-of-the-hand-off-process
#7
Craig Fryman, Carine Hamo, Siddharth Raghavan, Nirvani Goolsarran
There is mounting evidence that communication and hand-off failures are a root cause of two-thirds of sentinel events in hospitals. Several studies have shown that non-standardized hand-offs have yielded poor patient outcomes and adverse events. At Stony Brook University Hospital, there were numerous reported adverse events related to poor hand-off during the transfer of patient responsibility from one resident caregiver to the next. A resident-conducted root cause analysis identified lack of a standardized hand-off process and formal training on safe and efficient hand-off among caregivers as key contributing factors...
2017: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/28465831/interaction-between-the-gut-microbiome-and-mucosal-immune-system
#8
REVIEW
Na Shi, Na Li, Xinwang Duan, Haitao Niu
The gut microbiota, the largest symbiotic ecosystem with the host, has been shown to play important roles in maintaining intestinal homeostasis. Dysbiosis of the gut microbiome is caused by the imbalance between the commensal and pathogenic microbiomes. The commensal microbiome regulates the maturation of the mucosal immune system, while the pathogenic microbiome causes immunity dysfunction, resulting in disease development. The gut mucosal immune system, which consists of lymph nodes, lamina propria and epithelial cells, constitutes a protective barrier for the integrity of the intestinal tract...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28453097/-description-of-the-process-of-preparation-and-response-of-local-health-authorities-facing-the-introduction-of-the-chikungunya-virus-in-colombia-2014
#9
Ángela P Alarcón-Cruz, Edgar Prieto-Suárez
Objective To describe the process of preparation and response of local health authorities in key public health issues while facing the introduction stage of an unusual virus: Chikungunya in Colombia in 2014. Methods A cross-sectional study was conducted using a survey that was developed for this study and sent to Public Health coordinators and to the person in charge of vector borne-diseases in the country's territorial entities. Results 23 out of the 35 territories at risk from the transmission of Chikungunya agreed to answer the survey...
June 2016: Revista de Salud Pública
https://www.readbyqxmd.com/read/28446420/measuring-sexual-behavior-stigma-to-inform-effective-hiv-prevention-and-treatment-programs-for-key-populations
#10
Shauna Stahlman, James R Hargreaves, Laurel Sprague, Anne L Stangl, Stefan D Baral
BACKGROUND: The levels of coverage of human immunodeficiency virus (HIV) treatment and prevention services needed to change the trajectory of the HIV epidemic among key populations, including gay men and other men who have sex with men (MSM) and sex workers, have consistently been shown to be limited by stigma. OBJECTIVE: The aim of this study was to propose an agenda for the goals and approaches of a sexual behavior stigma surveillance effort for key populations, with a focus on collecting surveillance data from 4 groups: (1) members of key population groups themselves (regardless of HIV status), (2) people living with HIV (PLHIV) who are also members of key populations, (3) members of nonkey populations, and (4) health workers...
April 26, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28438218/malaria-elimination-in-lao-pdr-the-challenges-associated-with-population-mobility
#11
REVIEW
Sengchanh Kounnavong, Deyer Gopinath, Bouasy Hongvanthong, Chanthalone Khamkong, Odai Sichanthongthip
Although the Lao People's Democratic Republic (Lao PDR) is comparatively small landlocked country with patterns of both in- and out-migration, its human migration situation has been poorly studied. This is despite all of the country's 18 provinces sharing both official and unofficial border checkpoints with neighboring countries. Economic reforms in the last decade have seen a gradual increase in the promotion of foreign investment, and main towns and transportation networks have been expanding thus offering new opportunities for livelihoods and economic activities...
April 25, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28430095/window-of-opportunity-for-new-disease-surveillance-developing-keyword-lists-for-monitoring-mental-health-and-injury-through-syndromic-surveillance
#12
Ursula Lauper, Jian-Hua Chen, Shao Lin
Studies have documented the impact that hurricanes have on mental health and injury rates before, during, and after the event. Since timely tracking of these disease patterns is crucial to disaster planning, response, and recovery, syndromic surveillance keyword filters were developed by the New York State Department of Health to study the short- and long-term impacts of Hurricane Sandy. Emergency department syndromic surveillance is recognized as a valuable tool for informing public health activities during and immediately following a disaster...
April 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28418738/real-time-surveillance-of-infectious-diseases-taiwan-s-experience
#13
Shu-Wan Jian, Chiu-Mei Chen, Cheng-Yi Lee, Ding-Ping Liu
Integration of multiple surveillance systems advances early warning and supports better decision making during infectious disease events. Taiwan has a comprehensive network of laboratory, epidemiologic, and early warning surveillance systems with nationwide representation. Hospitals and clinical laboratories have deployed automatic reporting mechanisms since 2014 and have effectively improved timeliness of infectious disease and laboratory data reporting. In June 2016, the capacity of real-time surveillance in Taiwan was externally assessed and was found to have a demonstrated and sustainable capability...
March 2017: Health Security
https://www.readbyqxmd.com/read/28415565/rad52-deficiency-decreases-development-of-lung-squamous-cell-carcinomas-by-enhancing-immuno-surveillance
#14
Rachel Lieberman, Jing Pan, Qi Zhang, Ming You
RAD52 is involved in homologous recombination and DNA repair. This study focuses on lung cancer progression and how the DNA repair gene, Rad52, enables tumor cells to have sufficient genome integrity, i.e., the ability to repair lethal DNA damage, to avoid cell death. In this report, we analyze the phenotypic differences between wild type and Rad52-/- in inhibition of tumor phenotypes including cell growth, viability, cytolysis, and immune profiling. We demonstrated that loss of Rad52 not only increases the death of cells undergoing carcinogen-induced transformation in vivo, but that Rad52 loss also augments in vivo antitumor activity through an enhanced capacity for direct killing of LLC tumor cells by stimulated Rad52-/- NK and CD8+ T cells...
March 18, 2017: Oncotarget
https://www.readbyqxmd.com/read/28405765/coexpressed-modular-gene-expression-reveals-inverse-correlation-between-immune-responsive-transcription-and-aggressiveness-in-gastric-tumours
#15
Kalaivani Kalamohan, Dhanasekaran Rathinam, Ponmathi Panneerpandian, Kumaresan Ganesan
The existing large number of gene expression profiles of tumour samples offers a great advantage for the integrative functional genomic exploration of molecular dysregulation in cancers. The clusters of genes (modules) derived from a gastric cancer (GC) coexpression network were explored to understand their clinical and functional significance. Among the modules derived from the GC mRNA expression network, six modules were relatively highly expressed in diffuse type gastric tumours. Elevated expression of genes related to extracellular matrix (ECM), angiogenesis, collagen and intracellular cytoskeletal components and immune response were identified in these modules...
April 12, 2017: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/28392733/implementing-a-regional-integrated-laboratory-proficiency-testing-scheme-for-peripheral-health-facilities-in-east-africa
#16
Stephen Munene, Jackson Songok, Dennis Munene, Jane Carter
INTRODUCTION: Regular participation in external quality assessment (EQA) is critical for maintaining laboratory performance and is required for laboratory accreditation. Proficiency testing (PT) is effective for providing EQA, but available schemes rarely address the range of tests performed by peripheral laboratories in resource-limited settings. The East African Regional External Quality Assessment Scheme (EA-REQAS) was established in 2004 to address this need. MATERIALS AND METHODS: Surveys were distributed biannually comprising seven different panel materials and questions addressing laboratory, clinical and public health topics...
February 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28367433/flumob-enabling-surveillance-of-acute-respiratory-infections-in-health-care-workers-via-mobile-phones
#17
May Oo Lwin, Chee Fu Yung, Peiling Yap, Karthikayen Jayasundar, Anita Sheldenkar, Kosala Subasinghe, Schubert Foo, Udeepa Gayantha Jayasinghe, Huarong Xu, Siaw Ching Chai, Ashwin Kurlye, Jie Chen, Brenda Sze Peng Ang
Singapore is a hotspot for emerging infectious diseases and faces a constant risk of pandemic outbreaks as a major travel and health hub for Southeast Asia. With an increasing penetration of smart phone usage in this region, Singapore's pandemic preparedness framework can be strengthened by applying a mobile-based approach to health surveillance and control, and improving upon existing ideas by addressing gaps, such as a lack of health communication. FluMob is a digitally integrated syndromic surveillance system designed to assist health authorities in obtaining real-time epidemiological and surveillance data from health-care workers (HCWs) within Singapore, by allowing them to report influenza incidence using smartphones...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28361056/eliminating-dog-mediated-rabies-in-sikkim-india-a-10-year-pathway-to-success-for-the-sarah-program
#18
Helen Byrnes, Andrea Britton, Thinlay Bhutia
A third of the world rabies burden is in India. The Sikkim Anti-Rabies and Animal Health (SARAH) program is the first state-wide rabies program in India and demonstrates a successful One Health model of dog-mediated rabies elimination. The SARAH program was created in 2006 as a collaboration between the Government of Sikkim and international non-government organizations-Vets Beyond Borders and Fondation Brigitte Bardot. Activities are directed to canine rabies vaccination, humane dog population control, community education, and treatment of sick and injured animals...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28355612/strengthening-health-security-at-the-hajj-mass-gatherings-characteristics-of-the-infectious-diseases-surveillance-systems-operational-during-the-2015-hajj
#19
Badriah M Alotaibi, Saber Yezli, Abdul-Aziz A Bin Saeed, Abdulhafeez Turkestani, Amnah H Alawam, Kingsley L Bieh
Background: Hajj is one of the largest and the most ethnically and culturally diverse mass gatherings worldwide. The use of appropriate surveillance systems ensures timely information management for effective planning and response to infectious diseases threats during the pilgrimage. The literature describes infectious diseases prevention and control strategies for Hajj but with limited information on the operations and characteristics of the existing Hajj infectious diseases surveillance systems...
May 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28342074/evaluation-of-saefvic-a-pharmacovigilance-surveillance-scheme-for-the-spontaneous-reporting-of-adverse-events-following-immunisation-in-victoria-australia
#20
Hazel J Clothier, Nigel W Crawford, Melissa Russell, Heath Kelly, Jim P Buttery
INTRODUCTION: Australia is traditionally an early adopter of vaccines, therefore comprehensive and effective post-licensure vaccine pharmacovigilance is critical to maintain confidence in immunisation, both nationally and internationally. With adverse event following immunisation (AEFI) surveillance the responsibility of Australian jurisdictions, Victoria operates an enhanced passive AEFI surveillance system integrated with clinical services, called 'SAEFVIC' (Surveillance of Adverse Events Following Vaccination In the Community)...
March 24, 2017: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
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