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Integrated surveillance response

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https://www.readbyqxmd.com/read/29770078/evaluating-the-timeliness-of-reporting-in-a-first-nations-communicable-diseases-program
#1
A Lam, S Woods, N Ndubuka
Background: Timely reporting of communicable diseases is necessary to enable a prompt response to mitigate and control outbreaks. This is especially true among First Nations communities due to a number of factors, including unique social determinants of health, which can contribute to rapid disease transmission. Objective: To assess the timeliness of reporting for 12 notifiable communicable diseases in the Northern Inter-Tribal Health Authority, which includes 33 First Nations on-reserve communities in Northern Saskatchewan, Canada, and to assess whether there were differences in reporting times depending on degree of remoteness of community, season or year...
June 1, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29768102/identification-of-dengue-and-chikungunya-cases-among-suspected-cases-of-yellow-fever-in-the-democratic-republic-of-the-congo
#2
Sheila Makiala-Mandanda, Steve Ahuka-Mundeke, Jessica L Abbate, Elisabeth Pukuta-Simbu, Justus Nsio-Mbeta, Nicolas Berthet, Eric Maurice Leroy, Pierre Becquart, Jean-Jacques Muyembe-Tamfum
For more than 95% of acute febrile jaundice cases identified through surveillance for yellow fever, a reemerging arthropod-borne viral disease, no etiological exploration is ever done. The aim of this study was to test for other arthropod-borne viruses that can induce the same symptoms in patients enrolled in the yellow fever surveillance in the Democratic Republic of the Congo (DRC). Of 652 patients included in the surveillance of yellow fever in DRC from January 2003 to January 2012, 453 patients that tested negative for yellow fever virus (YFV) immunoglobulin M (IgM) antibodies were selected for the study...
May 16, 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29760830/patient-and-provider-perspectives-on-adherence-to-and-care-coordination-of-lynch-syndrome-surveillance-recommendations-findings-from-qualitative-interviews
#3
Jennifer L Schneider, Katrina A B Goddard, Kristin R Muessig, James V Davis, Alan F Rope, Jessica E Hunter, Susan K Peterson, Louise S Acheson, Sapna Syngal, Georgia L Wiesner, Jacob A Reiss
Background: Patients with a genetic variant associated with Lynch syndrome (LS) are recommended to undergo frequent and repeated cancer surveillance activities to minimize cancer-related morbidity and mortality. Little is known about how patients and primary care providers (PCPs) track and manage these recommendations. We conducted a small exploratory study of patient and PCP experiences with recommended LS surveillance activities and communication with family members in an integrated health care system...
2018: Hereditary Cancer in Clinical Practice
https://www.readbyqxmd.com/read/29751672/a-simulation-based-study-on-the-comparison-of-statistical-and-time-series-forecasting-methods-for-early-detection-of-infectious-disease-outbreaks
#4
Eunjoo Yang, Hyun Woo Park, Yeon Hwa Choi, Jusim Kim, Lkhagvadorj Munkhdalai, Ibrahim Musa, Keun Ho Ryu
Early detection of infectious disease outbreaks is one of the important and significant issues in syndromic surveillance systems. It helps to provide a rapid epidemiological response and reduce morbidity and mortality. In order to upgrade the current system at the Korea Centers for Disease Control and Prevention (KCDC), a comparative study of state-of-the-art techniques is required. We compared four different temporal outbreak detection algorithms: the CUmulative SUM (CUSUM), the Early Aberration Reporting System (EARS), the autoregressive integrated moving average (ARIMA), and the Holt-Winters algorithm...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29723168/malaria-surveillance-united-states-2015
#5
Kimberly E Mace, Paul M Arguin, Kathrine R Tan
PROBLEM/CONDITION: Malaria in humans is caused by intraerythrocytic protozoa of the genus Plasmodium. These parasites are transmitted by the bite of an infective female Anopheles species mosquito. The majority of malaria infections in the United States occur among persons who have traveled to regions with ongoing malaria transmission. However, malaria is occasionally acquired by persons who have not traveled out of the country through exposure to infected blood products, congenital transmission, laboratory exposure, or local mosquitoborne transmission...
May 4, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29718947/how-ownership-rights-over-microorganisms-affect-infectious-disease-control-and-innovation-a-root-cause-analysis-of-barriers-to-data-sharing-as-experienced-by-key-stakeholders
#6
Carolina Dos S Ribeiro, Martine Y van Roode, George B Haringhuizen, Marion P Koopmans, Eric Claassen, Linda H M van de Burgwal
BACKGROUND: Genetic information of pathogens is an essential input for infectious disease control, public health and for research. Efficiency in preventing and responding to global outbreaks relies on timely access to such information. Still, ownership barriers stand in the way of timely sharing of genetic data from pathogens, frustrating efficient public health responses and ultimately the potential use of such resources in innovations. Under a One Health approach, stakeholders, their interests and ownership issues are manifold and need to be investigated...
2018: PloS One
https://www.readbyqxmd.com/read/29713590/driving-towards-malaria-elimination-in-botswana-by-2018-progress-on-case-based-surveillance-2013-2014
#7
M Motlaleng, J Edwards, J Namboze, W Butt, K Moakofhi, M Obopile, M Manzi, K C Takarinda, R Zachariah, P Owiti, N Oumer, T Mosweunyane
Background: Reliable information reporting systems ensure that all malaria cases are tested, treated and tracked to avoid further transmission. Botswana aimed to eliminate malaria by 2018, and surveillance is key. This study focused on assessing the uptake of the new malaria case-based surveillance (CBS) system introduced in 2012, which captures information on malaria cases reported in the Integrated Disease Surveillance and Response (IDSR) system. Methods: This was a retrospective descriptive study based on routine data focusing on Ngami, Chobe and Okavango, three high-risk districts in Botswana...
April 25, 2018: Public Health Action
https://www.readbyqxmd.com/read/29703417/next-generation-microbiological-risk-assessment-potential-of-omics-data-for-hazard-characterisation
#8
Nabila Haddad, Nick Johnson, Sophia Kathariou, Aline Métris, Trevor Phister, Annemarie Pielaat, Chrysoula Tassou, Marjon H J Wells-Bennik, Marcel H Zwietering
According to the World Health Organization estimates in 2015, 600 million people fall ill every year from contaminated food and 420,000 die. Microbial risk assessment (MRA) was developed as a tool to reduce and prevent risks presented by pathogens and/or their toxins. MRA is organized in four steps to analyse information and assist in both designing appropriate control options and implementation of regulatory decisions and programs. Among the four steps, hazard characterisation is performed to establish the probability and severity of a disease outcome, which is determined as function of the dose of toxin and/or pathogen ingested...
April 12, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29671475/integrated-social-behavioral-and-ecological-risk-maps-to-prioritize-local-public-health-responses-to-lyme-disease
#9
Catherine Bouchard, Cécile Aenishaenslin, Erin E Rees, Jules K Koffi, Yann Pelcat, Marion Ripoche, François Milord, L Robbin Lindsay, Nicholas H Ogden, Patrick A Leighton
BACKGROUND: The risk of contracting Lyme disease (LD) can vary spatially because of spatial heterogeneity in risk factors such as social-behavior and exposure to ecological risk factors. Integrating these risk factors to inform decision-making should therefore increase the effectiveness of mitigation interventions. OBJECTIVES: The objective of this study was to develop an integrated social-behavioral and ecological risk-mapping approach to identify priority areas for LD interventions...
April 18, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29650500/zika-reveals-india-s-risk-communication-challenges-and-needs
#10
Santosh Vijaykumar, Aravind Sesagiri Raamkumar
India's approach to disseminating information about the first three cases of the Zika virus was criticised nationally and internationally after the issue came to light in May 2017 through a World Health Organization news release. We analyse the incident from a risk communication perspective. This commentary recaps the events and synthesises key arguments put forth by the news media and public health stakeholders. We use Peter Sandman's risk = hazard + outrage framework - also adopted by India's risk communication planners - to analyse India's risk communication response and contextualise it against the mandate of the National Risk Communication Plan and Integrated Disease Surveillance Programme...
April 12, 2018: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/29649515/a-biopsychosocial-model-of-body-image-disordered-eating-and-breastfeeding-among-postpartum-women
#11
Rachel F Rodgers, Jennifer L O'Flynn, Althea Bourdeau, Emily Zimmerman
BACKGROUND: The aim of the current study was to test a biopsychosocial model of body image, eating, and feeding attitudes among postpartum women. Specifically, the model predicted that desired weight-loss, depressive symptoms, and body surveillance would predict body dissatisfaction and appearance-related barriers to breastfeeding, which in turn would predict maternal disordered eating and breastfeeding self-efficacy. METHODS: Data from 151 women, mean age = 32...
April 9, 2018: Appetite
https://www.readbyqxmd.com/read/29629374/rna-surveillance-by-the-nuclear-rna-exosome-mechanisms-and-significance
#12
Koichi Ogami, Yaqiong Chen, James L Manley
The nuclear RNA exosome is an essential and versatile machinery that regulates maturation and degradation of a huge plethora of RNA species. The past two decades have witnessed remarkable progress in understanding the whole picture of its RNA substrates and the structural basis of its functions. In addition to the exosome itself, recent studies focusing on associated co-factors have been elucidating how the exosome is directed towards specific substrates. Moreover, it has been gradually realized that loss-of-function of exosome subunits affect multiple biological processes such as the DNA damage response, R-loop resolution, maintenance of genome integrity, RNA export, translation and cell differentiation...
2018: Non-Coding RNA
https://www.readbyqxmd.com/read/29618619/prevalent-homozygous-deletions-of-type-i-interferon-and-defensin-genes-in-human-cancers-associate-with-immunotherapy-resistance
#13
Liguo Wang, Zhenqing Ye, Haidong Dong, Ying Li, Tao Ma, Haojie Huang, Hon S Leong, Jeanette E Eckel-Passow, Jean-Pierre Kocher, Han Liang
PURPOSE: Homozygous deletions play important roles in carcinogenesis. The genome-wide screening for homozygously deleted genes in many different cancer types with a large number of patient specimens representing the tumor heterogeneity has not been done. EXPERIMENTAL DESIGN: We performed integrative analyses of the copy number profiles of 10,759 patients across 31 cancer types from The Cancer Genome Atlas project. RESULTS: We found that the Type-I interferon, α- and β-defensin genes were homozygously deleted in 19 cancer types with high frequencies (7%-31%, median = 12%; interquartile range = 10-16...
April 4, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29608561/kampala-manifesto-building-community-based-one-health-approaches-to-disease-surveillance-and-response-the-ebola-legacy-lessons-from-a-peer-led-capacity-building-initiative
#14
Petra Dickmann, Andrew Kitua, Franklin Apfel, Nigel Lightfoot
OVERVIEW: International activities to respond to the Ebola crisis in West Africa were mainly developed and focussed around the biomedical paradigm of Western health systems. This approach was often insensitive to societal perception, attitude, and behavioural determinants and clashed with community-based health traditions, narratives, and roles, e.g., of community health workers. In this peer-led capacity-building initiative, these deficiencies were identified and analysed. Innovative, more locally focussed, community-based solutions were articulated...
April 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29606220/functional-diversification-of-structurally-alike-nlr-proteins-in-plants
#15
REVIEW
Joydeep Chakraborty, Akansha Jain, Dibya Mukherjee, Suchismita Ghosh, Sampa Das
In due course of evolution many pathogens alter their effector molecules to modulate the host plants' metabolism and immune responses triggered upon proper recognition by the intracellular nucleotide-binding oligomerization domain containing leucine-rich repeat (NLR) proteins. Likewise, host plants have also evolved with diversified NLR proteins as a survival strategy to win the battle against pathogen invasion. NLR protein indeed detects pathogen derived effector proteins leading to the activation of defense responses associated with programmed cell death (PCD)...
April 2018: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/29601339/the-role-of-the-electronic-medical-record-in-the-intensive-care-unit-nurse-s-detection-of-patient-deterioration-a-qualitative-study
#16
Laurel A Despins, Bonnie J Wakefield
Failure to detect patient deterioration signals leads to longer stays in the hospital, worse functional outcomes, and higher hospital mortality rates. Surveillance, including ongoing acquisition, interpretation, and synthesis of patient data by the nurse, is essential for early risk detection. Electronic medical records promote accessibility and retrievability of patient data and can support patient surveillance. A secondary analysis was performed on interview data from 24 intensive care unit nurses, collected in a study that examined factors influencing nurse responses to alarms...
March 30, 2018: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/29593027/t-cell-dysfunction-in-glioblastoma-applying-a-new-framework
#17
Karolina I Woroniecka, Kristen E Rhodin, Pakawat Chongsathidkiet, Kristin A Keith, Peter E Fecci
A functional, replete T cell repertoire is an integral component to adequate immune surveillance and to the initiation and maintenance of productive anti-tumor immune responses. Glioblastoma (GBM), however, is particularly adept at sabotaging anti-tumor immunity, eliciting severe T cell dysfunction that is both qualitative and quantitative. Understanding and countering such dysfunction are among the keys to harnessing the otherwise stark potential of anti-cancer immune-based therapies. While T cell dysfunction in GBM is long described, newer immunologic frameworks now exist for re-classifying T cell deficits in a manner that better permits their study and reversal...
March 28, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29563241/measles-outbreak-response-decision-making-under-uncertainty-a-retrospective-analysis
#18
Christopher J Fonnesbeck, Katriona Shea, Spencer Carran, Jose Cassio de Moraes, Christopher Gregory, James L Goodson, Matthew J Ferrari
Resurgent outbreaks of vaccine-preventable diseases that have previously been controlled or eliminated have been observed in many settings. Reactive vaccination campaigns may successfully control outbreaks but must necessarily be implemented in the face of considerable uncertainty. Real-time surveillance may provide critical information about at-risk population and optimal vaccination targets, but may itself be limited by the specificity of disease confirmation. We propose an integrated modelling approach that synthesizes historical demographic and vaccination data with real-time outbreak surveillance via a dynamic transmission model and an age-specific disease confirmation model...
March 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29555027/integrating-plant-and-animal-biology-for-the-search-of-novel-dna-damage-biomarkers
#19
REVIEW
Zacharenia Nikitaki, Marcela Holá, Mattia Donà, Athanasia Pavlopoulou, Ioannis Michalopoulos, Karel J Angelis, Alexandros G Georgakilas, Anca Macovei, Alma Balestrazzi
Eukaryotic genome surveillance is dependent on the multiple, highly coordinated network functions of the DNA damage response (DDR). Highlighted conserved features of DDR in plants and animals represent a challenging opportunity to develop novel interdisciplinary investigations aimed at expanding the sets of DNA damage biomarkers currently available for radiation exposure monitoring (REM) in environmental and biomedical applications. In this review, common and divergent features of the most relevant DDR players in animals and plants are described, including the intriguing example of the plant and animal kingdom-specific master regulators SOG1 (suppressor of gamma response) and p53...
January 2018: Mutation Research
https://www.readbyqxmd.com/read/29530839/integrating-smart-health-in-the-us-health-care-system-infodemiology-study-of-asthma-monitoring-in-the-google-era
#20
Amaryllis Mavragani, Alexia Sampri, Karla Sypsa, Konstantinos P Tsagarakis
BACKGROUND: With the internet's penetration and use constantly expanding, this vast amount of information can be employed in order to better assess issues in the US health care system. Google Trends, a popular tool in big data analytics, has been widely used in the past to examine interest in various medical and health-related topics and has shown great potential in forecastings, predictions, and nowcastings. As empirical relationships between online queries and human behavior have been shown to exist, a new opportunity to explore the behavior toward asthma-a common respiratory disease-is present...
March 12, 2018: JMIR Public Health and Surveillance
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