Danielle M Allen, Marina I Reyne, Pearce Allingham, Ashley Levickas, Stephen H Bell, Jonathan Lock, Jonathon D Coey, Stephen Carson, Andrew J Lee, Cormac McSparron, Behnam Firoozi Nejad, James McKenna, Mark Shannon, Kathy Li, Tanya Curran, Lindsay J Broadbent, Damian G Downey, Ultan F Power, Helen E Groves, Jennifer M McKinley, John W McGrath, Connor G G Bamford, Deirdre F Gilpin
Respiratory syncytial virus (RSV) causes severe infections in infants, immunocompromised or elderly individuals resulting in annual epidemics of respiratory disease. Currently, limited clinical surveillance and the lack of predictable seasonal dynamics limits the public health response. Wastewater-based epidemiology (WBE) has recently been used globally as a key metric in determining prevalence of SARS-CoV-2 in the community but its application to other respiratory viruses is limited. In this study, we present an integrated genomic WBE approach, applying RT-qPCR and partial G-gene sequencing to track RSV levels and variants in the community...
April 18, 2024: Journal of Infectious Diseases