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Wound sepsis

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https://www.readbyqxmd.com/read/28437804/-prognostic-factors-of-open-abdomen-treatment-in-visceral-surgery
#1
Martin W von Websky, Agnes Jedig, Arnulf Willms, Azin Jafari, Hanno Matthaei, Jörg C Kalff, Steffen Manekeller
Introduction In general surgery, open abdomen treatment (OAT) is used to treat abdominal compartment syndrome (ACS) and sepsis, often after a primary surgical procedure associated with complications. The results achieved in this patient population may depend on factors that are yet unknown. This study evaluates independent patient-related prognostic factors after OAT. Methods 38 clinical parameters and survival data of 165 consecutive general surgery patients after OAT were entered into a prospective database according to a defined algorithm in order to analyse the underlying surgical pathology, predictors of survival and important aspects of OAT-related morbidity...
April 24, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/28436176/does-bowel-preparation-for-inflammatory-bowel-disease-surgery-matter
#2
C Shwaartz, A C Fields, M Sobrero, C M Divino
AIM: The purpose of this study is to determine if bowel preparation influences outcomes in inflammatory bowel disease patients undergoing surgery. METHODS: The American College Surgeons National Surgical Quality Improvement Program, Procedure Targeted Colectomy databases from 2012-2014 were analyzed. Inflammatory bowel disease patients undergoing colorectal resection with or without bowel preparation were included in the study. RESULTS: There were 3,679 patients with inflammatory bowel disease identified...
April 24, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28425162/a-small-lick-will-sink-a-great-ship-fulminant-septicaemia-after-dog-saliva-wound-treatment-in-an-asplenic-patient
#3
Evi M Morandi, Reinhard Pauzenberger, Christoph Tasch, Ulrich M Rieger, Gerhard Pierer, Gabriel Djedovic
Capnocytophaga canimorsus is a bacterium transmitted through the saliva of dogs. An infection can cause severe sepsis with acral necrosis and is potentially fatal. Here, we report the case of a 41-year-old man who was infected through a wound that was licked by his dog. He went into septic shock with disseminated intravascular coagulation and subsequently lost both lower legs, his nose and all the fingers on both hands.
April 19, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28412932/isolation-of-enterococci-their-antimicrobial-susceptibility-patterns-and-associated-factors-among-patients-attending-at-the-university-of-gondar-teaching-hospital
#4
Amelework Yilema, Feleke Moges, Sisay Tadele, Mengistu Endris, Afework Kassu, Wondwossen Abebe, Getnet Ayalew
BACKGROUND: Enterococci become clinically important especially in immune compromised patients and important causes of nosocomial infections. Data on the prevalence, antimicrobial susceptibility patterns and associated factors of enterococci are scarce in Ethiopia. METHODS: A hospital based cross-sectional study was conducted at the University of Gondar Teaching Hospital from February 28, 2014 to May 1, 2014. Pretested structured questionnaire was used to collect socio-demographic data and possible associated factors of enterococci infections...
April 17, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28399544/intrawound-tobramycin-powder-eradicates-surgical-wound-contamination-an-in-vivo-rabbit-study
#5
Joseph L Laratta, Jamal N Shillingford, Nathan Hardy, Joseph M Lombardi, Comron Saifi, Alexander Romanov, Lawrence G Lenke, Ronald A Lehman, K Daniel Riew
STUDY DESIGN: Therapeutic anti-infective trial in rabbitsOBJECTIVE.: The purpose of the present study was to assess the efficacy of intrawound tobramycin powder in terms of eradicating a known bacterial contamination in an Escherichia coli infected rabbit spinal implantation model. SUMMARY OF BACKGROUND DATA: Implant-associated surgical site infections (SSI) remain a dreaded complication of spinal surgery. Currently, over 30% of all spine SSIs are secondary to gram-negative bacteria...
April 10, 2017: Spine
https://www.readbyqxmd.com/read/28387059/pouch-excision-indications-and-outcomes
#6
Amy L Lightner, Sheev Dattani, Eric J Dozois, Sara B Moncrief, John H Pemberton, Kellie L Mathis
INTRODUCTION: Resotrative proctolectomy (RPC) with Ileal-pouch anal anastomosis (IPAA) is the procedure of choice for ulcerative colitis. Unfortunately, up to 10% of pouches will fail, requiring either reconstruction or excision. While several series have reported on the aetiology of pouch failure, no study to date has focused on the postoperative complications associated with pouch excision. METHODS: Patients who had excision of ileoanal reservoir with ileostomy (CPT code 45136) were included...
April 7, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28379857/postsurgical-pyoderma-gangrenosum-versus-necrotizing-fasciitis-can-we-spot-the-difference
#7
Leila L Touil, Dilnath A R Gurusinghe, Amir Sadri, Ahmed El-Gawad, Fahmy S Fahmy
BACKGROUND: Pyoderma gangrenosum is a rare noninfectious cutaneous disease characterized by expanding areas of skin ulceration around necrotic centers with purulent debris. Exceptionally, it can be precipitated by surgery alone, and this entity has been described as postsurgical pyoderma gangrenosum (PSPG). Cases of PSPG in the literature are rare. METHODS: We performed a retrospective review of the current literature on PSPG and highlight some observed differences between these conditions...
May 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28368977/cutaneous-burn-injury-promotes-shifts-in-the-bacterial-microbiome-in-autologous-donor-skin-implications-for-skin-grafting-outcomes
#8
Jennifer K Plichta, Xiang Gao, Huaiying Lin, Qunfeng Dong, Evelyn Toh, David E Nelson, Richard L Gamelli, Elizabeth A Grice, Katherine A Radek
INTRODUCTION: The cutaneous microbiome maintains skin barrier function, regulates inflammation, and stimulates wound healing responses. Burn injury promotes an excessive activation of the cutaneous and systemic immune response directed against commensal and invading pathogens. Skin grafting is the primary method of reconstructing full-thickness burns, and wound infection continues to be a significant complication. METHODS: In this study, the cutaneous bacterial microbiome was evaluated and subsequently compared to patient outcomes...
March 31, 2017: Shock
https://www.readbyqxmd.com/read/28368347/the-role-of-th-17-cells-and-%C3%AE-%C3%AE-t-cells-in-modulating-the-systemic-inflammatory-response-to-severe-burn-injury
#9
REVIEW
Albert Kim, Thomas Lang, Meilang Xue, Aruna Wijewardana, Chris Jackson, John Vandervord
Burns are a global public health problem, accounting for an estimated 265,000 deaths annually. Inflammation is essential in supplying the growth factors, cytokines and chemokines needed to recruit T-cells and myeloid cells to the site of a burn injury for wound healing. However, major burns generate a marked pathophysiological inflammatory response through a widespread release of abundant pro-inflammatory mediators that predispose patients to a systemic inflammatory response syndrome, sepsis and multi-organ failure...
April 3, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28365269/does-promoting-resolution-instead-of-inhibiting-inflammation-represent-the-new-paradigm-in-treating-infections
#10
REVIEW
Jesmond Dalli
Infections arise when the host response is overwhelmed by pathogens leading to organ dysfunction. In some instances patients progress to more severe conditions, including septic shock, that are associated with increased mortality. Current strategies in treating infections aim at either blocking inflammation using inhibitors to pro-inflammatory molecules and/or inhibiting bacterial growth using antibiotics. These approaches find their origins in studies conducted by Joseph Lister who demonstrated that applying carbolic acid to wounds promoted wound healing without suppuration, reducing both the necessity of amputation and mortality...
April 5, 2017: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/28364952/early-complications-after-percutaneous-radiofrequency-ablation-for-hepatocellular-carcinoma-an-analysis-of-1-843-ablations-in-1-211-patients-in-a-single-centre-experience-over-10-years
#11
J G Park, S Y Park, W Y Tak, Y O Kweon, S Y Jang, Y R Lee, K Hur, H J Lee, H W Lee
AIM: To evaluate the incidence of adverse events and associated factors after radiofrequency ablation (RFA) in patients with hepatocellular carcinoma within 30 days. MATERIALS AND METHODS: The early complications that occurred within 30 days after RFA at a single institution from January 2000 to July 2010 were reviewed in order to evaluate the morbidity, mortality, and risk factors associated with the complications. In total, 1,211 patients (845 men, 70.5%) with a mean age of 68 years (range, 27-88 years) underwent 1,843 RFA procedures...
March 29, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28363300/microsurgical-reconstruction-of-the-burned-hand-and-upper-extremity
#12
REVIEW
Mauricio De la Garza, Michael Sauerbier, Germann Günter, Curtis L Cetrulo, Reuben A Bueno, Robert C Russell, Michael W Neumeister
Improvements in critical care and burn victim resuscitation have led to increased survival of burned patients. Initial resuscitation, early excision of burned tissues, prevention of burn wound sepsis, and wound coverage remain mainstays of care. Many burn wounds require complex reconstruction. This is particularly important in the hand. Coverage of tendons, ligaments, joints, vessels, nerves, and bones of the hand requires healthy vascularized tissue to maintain viability and function. Local flaps or regional flaps may be within the burn zone of injury...
May 2017: Hand Clinics
https://www.readbyqxmd.com/read/28358979/pelvimetry-for-fetal-cephalic-presentations-at-or-near-term-for-deciding-on-mode-of-delivery
#13
REVIEW
Robert C Pattinson, Anna Cuthbert, Valerie Vannevel
BACKGROUND: Pelvimetry assesses the size of a woman's pelvis aiming to predict whether she will be able to give birth vaginally or not. This can be done by clinical examination, or by conventional X-rays, computerised tomography (CT) scanning, or magnetic resonance imaging (MRI). OBJECTIVES: To assess the effects of pelvimetry (performed antenatally or intrapartum) on the method of birth, on perinatal mortality and morbidity, and on maternal morbidity. This review concentrates exclusively on women whose fetuses have a cephalic presentation...
March 30, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28350238/safety-and-effectiveness-of-robot-assisted-versus-open-radical-cystectomy-for-bladder-cancer-a-systematic-review-and-meta-analysis
#14
Soo Kyung Son, Na Rae Lee, Seok Ho Kang, Seon Heui Lee
OBJECTIVES: To evaluate the safety and effectiveness of robot-assisted radical cystectomy (RARC) compared with open radical cystectomy (ORC) in bladder cancer. METHODS: A literature search for the systematic review was conducted using international databases as well as domestic databases up to April 2015. Outcomes of interest included baseline characteristics, complication rates, perioperative, and oncologic outcomes. RESULTS: Twenty-four articles were finally selected for inclusion in the meta-analysis...
March 28, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28342028/disparities-in-knee-and-hip-arthroplasty-outcomes-an-observational-analysis-of-the-acs-nsqip-clinical-registry
#15
Peter Cram, Gillian Hawker, John Matelski, Bheeshma Ravi, Andrew Pugely, Rajiv Gandhi, Timothy Jackson
BACKGROUND: Disparities in total joint arthroplasty (TJA) have largely been studied in single center studies and using administrative data. Our objective was to investigate differences in TJA outcomes in white men, black men, white women, and black women using a large international registry. METHODS: We used 2010-2013 data from the ACS-NSQIP to identify four groups of adults (white men, black men, white women, black women) who underwent primary total knee arthroplasty (TKA) or total hip arthroplasty (THA)...
March 24, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28331144/totally-extraperitoneal-tep-removal-of-an-infected-mesh-by-laparoscopy-after-open-preperitoneal-repair-initial-case-report
#16
Naoto Chihara, Keisuke Mishima, Hideyuki Suzuki, Masanori Watanabe, Tetsutaka Toyoda, Eiji Uchida
Prosthetic mesh infection after open or laparoscopic hernia repair is a rare complication. Superficial wound infection can be resolved by treatment with a combination of antibiotics and wound drainage, whereas deep-seated mesh infection, which can lead to chronic groin sepsis, usually requires removal of the mesh. A 56-year-old Japanese man was admitted to our hospital for the treatment of deep-seated mesh infection. The patient had undergone inguinal hernia repair at another hospital 18 months earlier. The operation was prosthetic mesh repair via an anterior approach...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/28331019/extraperitoneal-abscess-originating-from-an-ischorectal-abscess
#17
Eman Hamza, Mirza Faraz Saeed, Amro Salem, Isam Mazin
We describe a case which had ongoing sepsis, despite adequate incision and drainage performed for an ischorectal abscess. The patient was then noted to have an ascending infection reaching the extraperitoneal space of the abdominal cavity. The case reported required multiple episodes of drainage along with lower midline incision for deep-situated abscess. Postoperatively, the abdominal wound was treated with vacuum-assisted closure dressing and antibiotics. The patient was doing well and was discharged with an appointment at the surgical outpatient department...
March 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28323799/a-prospective-randomized-trial-to-assess-oral-versus-intravenous-antibiotics-for-the-treatment-of-postoperative-wound-infection-after-extremity-fractures-poviv-study
#18
William T Obremskey, Andrew H Schmidt, Robert V OʼToole, Jennifer DeSanto, Saam Morshed, Paul Tornetta, Clinton K Murray, Clifford B Jones, Daniel O Scharfstein, Tara J Taylor, Anthony R Carlini, Renan C Castillo
Patients surgically treated for infection after extremity fractures are typically discharged with a 6- to 12-week antibiotic regimen. Intravenous (IV) antibiotics are associated with significant cost and potential complications of deep vein thrombosis, line clotting, and sepsis. Many of the pathogens that cause musculoskeletal infection have both oral (PO) and IV antibiotic options with adequate bioavailability and antibacterial effect, yet IV antibiotics remain the standard of care absent evidence that PO options are clinically as efficacious...
April 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28323791/obesity-is-associated-with-high-peri-operative-complications-among-surgically-treated-intertrochanteric-fracture-of-the-femur
#19
Harish Kempegowda, Raveesh Richard, Amrut Borade, Akhil Tawari, Graham Jove, Michael Suk, Abby Howenstein, Erik N Kubiak, Vanessa Rojas Sotomayor, Kenneth Koval, Frank A Liporace, Nirmal Tejwani, Daniel S Horwitz
OBJECTIVES: The purpose of this study was to document the complications among obese patients who underwent surgical fixation for intertrochanteric femur fractures and to compare with non-obese patients. DESIGN: Retrospective cohort study SETTING:: Four level I trauma centers. PATIENTS: 1078 intertrochanteric femur fracture patients INTERVENTIONS:: None MAIN OUTCOME MEASURES:: Patient and fracture characteristics, surgical duration, surgical delay intra-operative and post-operative complications, inpatient mortality and length of stay...
March 8, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28320052/soft-tissue-infections-from-fish-spike-wounds-normal-commensal-bacteria-are-more-common-than-marine-pathogens
#20
Hannah Collins, Kin Mun Lee, Paul T-Y Cheng, Sarah Hulme
BACKGROUND: A fish spike injury can be sustained by anyone handling fish; during fishing, meal preparation or in retail. Case reports of fish spikes inoculating victims with virulent marine-specific pathogens and causing systemic illness led us to question whether empirical treatment of these injuries with amoxicillin and clavulanic acid is adequate. METHODS: This 2-year prospective observational study was conducted at Middlemore Hospital, Auckland, New Zealand...
March 20, 2017: ANZ Journal of Surgery
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