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https://www.readbyqxmd.com/read/28731055/choroidal-excavation-in-choroidal-osteoma-complicated-by-choroidal-neovascularization
#1
L Pierro, A Marchese, M Gagliardi, U Introini, M Battaglia Parodi, G Casalino, F Bandello
PurposeTo describe multimodal imaging features of choroidal osteoma (CO) complicated by choroidal neovascularization (CNV) and focal choroidal excavation (FCE).MethodsPatients presenting with CO and CNV between January and October 2016 were considered for this study. Diagnosis of CO was confirmed by ultrasound examination. All patients underwent multimodal imaging including optical coherence tomography (OCT), swept-source OCT angiography (DRI OCT Triton, Topcon, Inc., Tokyo, Japan) and fluorescein angiography (Spectralis HRA+OCT; Heidelberg Engineering, Heidelberg, Germany)...
July 21, 2017: Eye
https://www.readbyqxmd.com/read/28730114/diagnostic-capability-of-peripapillary-retinal-nerve-fiber-layer-parameters-in-time-domain-versus-spectral-domain-optical-coherence-tomography-for-assessing-glaucoma-in-high-myopia
#2
Mei-Ching Teng, Yi-Chieh Poon, Kuo-Chi Hung, Hsueh-Wen Chang, Ing-Chou Lai, Jen-Chia Tsai, Pei-Wen Lin, Chien-Yun Wu, Chueh-Tan Chen, Pei-Chang Wu
AIM: To evaluate and compare the diagnostic capabilities of peripapillary retinal nerve fiber layer (p-RNFL) parameters of Spectralis optical coherence tomography (OCT) versus Stratus OCT to detect glaucoma in patients with high myopia. METHODS: This is a retrospective, cross-sectional study. Sixty highly myopic eyes of 60 patients were enrolled, with 30 eyes in the glaucoma group and 30 eyes in the control group. All eyes received peripapillary imaging of the optic disc using Stratus and Spectralis OCT...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28723847/blindness-related-to-presumed-retinal-toxicity-after-using-perfluorocarbon-liquid-during-vitreoretinal-surgery
#3
Silvia Méndez-Martínez, Pilar Calvo, Nelson Arturo Rodriguez-Marco, Fernando Faus, Emilio Abecia, Luis Pablo
PURPOSE: To describe the presumed retinal toxicity after using specific batches of perfluorocarbon liquid ALA OCTA (Alamedics, Dornstadt, Germany) in pars plana vitrectomy. METHODS: This is an observational retrospective consecutive case series analyses of patients operated on pars plana vitrectomy for retinal detachment or intraocular lens subluxation, using the 150141 or 200114 batches of perfluorocarbon liquid ALA OCTA as assistance during the surgery in a single center...
July 18, 2017: Retina
https://www.readbyqxmd.com/read/28678834/normative-database-for-separate-inner-retinal-layers-thickness-using-spectral-domain-optical-coherence-tomography-in-caucasian-population
#4
María Nieves-Moreno, Jose M Martínez-de-la-Casa, Pilar Cifuentes-Canorea, Marina Sastre-Ibáñez, Enrique Santos-Bueso, Federico Sáenz-Francés, Laura Morales-Fernández, Julián García-Feijoó
PURPOSE: Develop the first normative database of the thickness of every inner retinal layer in the macular area in a healthy, Caucasian population between 18 to 87 years old, using Spectralis Optical Coherence Tomography (OCT). METHODS: On this transversal, observational study, 300 patients between 18 to 87 years old and without an ophthalmological condition were recruited. Macular OCT scans were performed on all patients (Spectralis OCT, Heidelberg Engineering)...
2017: PloS One
https://www.readbyqxmd.com/read/28660077/relationship-between-retinal-nerve-fiber-layer-thickness-and-hemoglobin-present-in-the-optic-nerve-head-in-glaucoma
#5
Marta Gonzalez-Hernandez, Jose Sigut Saavedra, Manuel Gonzalez de la Rosa
PURPOSE: To observe the relationship between topographic hemoglobin levels in the optic nerve head (ONH), the rim thickness (BMO-MRW), and retinal nerve fiber layer (RNFL) thickness. METHODS: 96 normal eyes and 82 glaucomas were examined using TOP strategy (Octopus 300 perimeter), SPECTRALIS OCT, and Laguna ONhE program which estimates hemoglobin from conventional color photographs (Horus Scope DEC 200 fundus camera). RESULTS: The correlation between Laguna ONhE glaucoma discriminant function (GDF) and SPECTRALIS BMO-MRW was R = 0...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28658477/machine-learning-of-the-progression-of-intermediate-age-related-macular-degeneration-based-on-oct-imaging
#6
Hrvoje Bogunovic, Alessio Montuoro, Magdalena Baratsits, Maria G Karantonis, Sebastian M Waldstein, Ferdinand Schlanitz, Ursula Schmidt-Erfurth
Purpose: To develop a data-driven interpretable predictive model of incoming drusen regression as a sign of disease activity and identify optical coherence tomography (OCT) biomarkers associated with its risk in intermediate age-related macular degeneration (AMD). Methods: Patients with AMD were observed every 3 months, using Spectralis OCT imaging, for a minimum duration of 12 months and up to a period of 60 months. Segmentation of drusen and the overlying layers was obtained using a graph-theoretic method, and the hyperreflective foci were segmented using a voxel classification method...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28654631/changes-in-choroidal-thickness-in-clinically-significant-pseudophakic-cystoid-macular-edema
#7
Efrat Fleissig, Shai Cohen, Matias Iglicki, Michaella Goldstein, Dinah Zur
PURPOSE: To investigate choroidal thickness in eyes with clinically significant pseudophakic cystoid macular edema (PCME) during the acute phase and following resolution of the edema, using enhanced depth imaging spectral domain optical coherence tomography (EDI-OCT). METHODS: This is a retrospective, observational clinical study. Patients' records were reviewed for cases of clinically significant PCME after uneventful phacoemulsification surgery. Choroidal thickness was measured at time of PCME diagnosis in both eyes and after CME resolution in the affected eye using enhanced depth imaging spectral domain optical coherence tomography (Spectralis; Heidelberg Engineering)...
June 20, 2017: Retina
https://www.readbyqxmd.com/read/28643709/comparison-of-central-corneal-thickness-with-four-noncontact-devices-an-agreement-analysis-of-swept-source-technology
#8
Erhan Ozyol, Pelin Özyol
PURPOSE: The purpose of this study was to compare the central corneal thickness (CCT) measurements of four noncontact devices in healthy eyes. MATERIALS AND METHODS: In a sample of 45 healthy controls, CCT was measured using an optical biometer (IOLMaster 700) based on swept-source optical coherence tomography (SS-OCT), high-resolution rotating Scheimpflug camera system (Pentacam HR), spectral-domain OCT (SD-OCT) device with an anterior segment module (Spectralis), and noncontact pachymetry (NCP) device (Topcon TRK-2P)...
June 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28641680/ophthalmological-evaluation-of-integrated-resistance-and-aerobic-training-during-70-day-bed-rest
#9
Giovanni Taibbi, Ronita L Cromwell, Susana B Zanello, Patrice O Yarbough, Robert J Ploutz-Snyder, Bernard F Godley, Gianmarco Vizzeri
INTRODUCTION: We evaluated ophthalmic changes in healthy individuals who underwent integrated resistance and aerobic training (iRAT) during 70-d 6° head-down tilt (HDT) bed rest (BR). METHODS: Participants were selected using NASA standard screening procedures. Standardized NASA BR conditions were implemented. Subjects were randomly assigned to the iRAT protocol or no exercise during HDTBR. Weekly ophthalmic examinations were performed in the sitting (pre/post-BR only) and HDT (BR only) positions...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28632847/pattern-recognition-analysis-of-age-related-retinal-ganglion-cell-signatures-in-the-human-eye
#10
Nayuta Yoshioka, Barbara Zangerl, Lisa Nivison-Smith, Sieu K Khuu, Bryan W Jones, Rebecca L Pfeiffer, Robert E Marc, Michael Kalloniatis
Purpose: To characterize macular ganglion cell layer (GCL) changes with age and provide a framework to assess changes in ocular disease. This study used data clustering to analyze macular GCL patterns from optical coherence tomography (OCT) in a large cohort of subjects without ocular disease. Methods: Single eyes of 201 patients evaluated at the Centre for Eye Health (Sydney, Australia) were retrospectively enrolled (age range, 20-85); 8 × 8 grid locations obtained from Spectralis OCT macular scans were analyzed with unsupervised classification into statistically separable classes sharing common GCL thickness and change with age...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28632031/mr-imaging-of-the-anterior-visual-pathway-in-primary-open-angle-glaucoma-correlation-with-octopus-101-perimetry-and-spectralis-optical-coherence-tomography-findings
#11
Mehmet Giray Ersoz, Yeliz Pekcevik, Emre Ayintap, İrfan Botan Gunes, Duygu Kunak Mart, Ersin Yucel, Gamze Türe
PURPOSE: To investigate structural changes in the visual pathway measured by magnetic resonance imaging (MRI) and its relationship with the clinical severity of glaucoma in primary open-angle glaucoma (POAG) patients. MATERIALS AND METHODS: The study included 28 patients with POAG and 26 age- and sex-matched healthy volunteers. All the subjects underwent spectral domain optical coherence tomography (OCT) of the peripapillary retina nerve fiber layer (RNFL). The optic nerve diameter (OND), chiasma height (Ch), and lateral geniculate nucleus height (LGNh) were measured bilaterally using a 1...
February 28, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28630764/impact-of-b-scan-averaging-on-spectralis-optical-coherence-tomography-image-quality-before-and-after-cataract-surgery
#12
Dominika Podkowinski, Ehsan Sharian Varnousfaderani, Christian Simader, Hrvoje Bogunovic, Ana-Maria Philip, Bianca S Gerendas, Ursula Schmidt-Erfurth, Sebastian M Waldstein
BACKGROUND AND OBJECTIVE: To determine optimal image averaging settings for Spectralis optical coherence tomography (OCT) in patients with and without cataract. STUDY DESIGN/MATERIAL AND METHODS: In a prospective study, the eyes were imaged before and after cataract surgery using seven different image averaging settings. Image quality was quantitatively evaluated using signal-to-noise ratio, distinction between retinal layer image intensity distributions, and retinal layer segmentation performance...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28615022/correlation-of-retinal-nerve-fibre-layer-and-macular-thickness-with-serum-uric-acid-among-type-2-diabetes-mellitus
#13
Munisamy-Naidu Vinuthinee-Naidu, Embong Zunaina, Anuar Azreen-Redzal, Naing Nyi-Nyi
BACKGROUND: Uric acid is a final breakdown product of purine catabolism in humans. It's a potent antioxidant and can also act as a pro-oxidant that induces oxidative stress on the vascular endothelial cells, thus mediating progression of diabetic related diseases. Various epidemiological and experimental evidence suggest that uric acid has a role in the etiology of type 2 diabetes mellitus. We conducted a cross-sectional study to evaluate the correlation of retinal nerve fibre layer (RNFL) and macular thickness with serum uric acid in type 2 diabetic patients...
June 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28608030/intracorneal-ring-segment-depth-in-keratoconus-patients-a-long-term-follow-up-study
#14
Saied Shahhoseini, Hassan Hashemi, Soheila Asgari
PURPOSE: To compare the actual depth of the tunnel created with femtosecond laser for intracorneal ring segment (ICRS) implantation with the target depth in keratoconus patients. METHODS: In this mix design study, eligible keratoconus patients were identified through chart review. The inclusion criterion was a history of ICRS implantation with femtosecond laser more than 6 months prior to enrollment. Participants underwent anterior segment optical coherence tomography using Spectralis (Heidelberg Engineering GmbH, Heidelberg, Germany) for depth measurement defined as the distance from the anterior corneal surface to anterior rim of the ring...
June 12, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28588646/the-effects-of-tolterodine-on-anterior-segment-and-choroidal-thickness-in-patients-with-overactive-bladder-syndrome
#15
Hande Hüsniye Telek, Omer Gokhan Doluoglu, Ayse Burcu, Gulizar Demirok, Firdevs Ornek, Ali Ayyildiz
BACKGROUND: To evaluate the effects of tolterodine on anterior segment and choroidal thickness by using the Pentacam system and optical coherence tomography (OCT) (Pentacam). METHODS: A total of 122 eyes of 61 patients (34 female; 27 male) were included in the study. All patients underwent a regular ocular examination and intraocular pressure measurements before and after 3 months of antimuscarinic drug tolterodine treatment, in addition, pupil diameter, anterior chamber depth, anterior chamber volume, anterior chamber angle, and lens thickness were measured through Pentacam (Oculus Inc...
October 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/28574923/evaluation-of-patchy-atrophy-secondary-to-high-myopia-by-semiautomated-software-for-fundus-autofluorescence-analysis
#16
Alexandra Miere, Vittorio Capuano, Rita Serra, Camille Jung, Eric Souied, Giuseppe Querques
PURPOSE: To evaluate the progression of patchy atrophy in high myopia using semiautomated software for fundus autofluorescence (FAF) analysis. METHODS: The medical records and multimodal imaging of 21 consecutive highly myopic patients with macular chorioretinal patchy atrophy (PA) were retrospectively analyzed. All patients underwent repeated fundus autofluorescence and spectral domain optical coherence tomography over at least 12 months. Color fundus photography was also performed in a subset of patients...
May 31, 2017: Retina
https://www.readbyqxmd.com/read/28564701/the-impact-of-lens-opacity-on-sd-oct-retinal-nerve-fiber-layer-and-bruch-s-membrane-opening-measurements-using-the-anatomical-positioning-system-aps
#17
Matthias M Mauschitz, Felix Roth, Frank G Holz, Monique M B Breteler, Robert P Finger
Purpose: To evaluate the impact of lens opacity on retinal nerve fiber layer thickness (RNFLT) and Bruch's membrane opening (BMO) measurements. Methods: Fifty-nine randomly selected patients without any other relevant ocular pathology undergoing elective routine cataract surgery in two specialized eye clinics were enrolled. RNFLT, BMO area, and BMO minimum rim width (BMO-MRW) were assessed with the Heidelberg Engineering Spectralis OCT using the anatomical positioning system (APS) prior to and 1 day after cataract surgery using a ring scan at different eccentricities of the disc (3...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28560468/-ultra-widefield-angiography-for-retinal-vein-occlusion-how-large-is-large-enough
#18
M Storch, S Bemme, M Rehak, H Hoerauf, N Feltgen
BACKGROUND: The introduction of full fundus angiography (FAG) for retinal vein occlusion (RVO) has enriched diagnostic imaging; however, it is unclear how much of the retina has to be visualized to evaluate the risk of neovascularization. We investigated the 102° Spectralis camera to assess if imaging beyond the central 102° is necessary. METHODS: In this retrospective study we assessed 80 eyes of 80 patients with RVO to analyze central and peripheral ischemia using the ultra-widefield 102° Spectralis camera...
May 30, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28559725/green-laser-induced-foveal-cyst-sustained-in-a-recreational-laser-light-show
#19
Rukiye Aydin, Merve Ozbek, Mustafa Ozsutcu, Fevzi Senturk
We report the case of a 9-year-old boy complained of visual loss in his right eye after watching green laser light show being hit by a ray of a laser at shopping center before five days ago. The laser had a maximum power rating of 30 mW (US Food and Drug Administration class IIIB). Best-corrected visual acuity in his right eye was 0.2 with Snellen at 5 days after the injury. Dilated fundoscopic examination demonstrated a macular hole appearance in the right eye. Spectral domain optical coherence tomography (OCT, Spectralis, Heidelberg Engineering, Heidelberg, Germany) demonstrates a steep fovea contour, a thickening of the macular edges, intraretinal cysts, disruption of the photoreceptor inner segment/outer segment layer and macular pseudohole formation...
April 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28541963/correlation-of-structural-and-functional-outcome-measures-in-a-phase-one-trial-of-ciliary-neurotrophic-factor-in-type-2-idiopathic-macular-telangiectasia
#20
Ferenc B Sallo, Irene Leung, Traci E Clemons, Tunde Peto, Emily Y Chew, Daniel Pauleikhoff, Alan C Bird
PURPOSE: Macular telangiectasia Type 2 is a bilateral, progressive, potentially blinding retinal disease characterized by both vascular and neurodegenerative signs. Both the area of the break in the ellipsoid zone seen in "en face" optical coherence tomographic (OCT) images and microperimetric focal retinal sensitivity loss have been proposed as potential measures of progression in macular telangiectasia. The authors aimed to assess the characteristics and interrelationship of these structural and functional disease markers from the data collected in a phase one clinical trial of ciliary neurotrophic factor in macular telangiectasia...
May 23, 2017: Retina
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