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https://www.readbyqxmd.com/read/28643709/comparison-of-central-corneal-thickness-with-four-noncontact-devices-an-agreement-analysis-of-swept-source-technology
#1
Erhan Ozyol, Pelin Özyol
PURPOSE: The purpose of this study was to compare the central corneal thickness (CCT) measurements of four noncontact devices in healthy eyes. MATERIALS AND METHODS: In a sample of 45 healthy controls, CCT was measured using an optical biometer (IOLMaster 700) based on swept-source optical coherence tomography (SS-OCT), high-resolution rotating Scheimpflug camera system (Pentacam HR), spectral-domain OCT (SD-OCT) device with an anterior segment module (Spectralis), and noncontact pachymetry (NCP) device (Topcon TRK-2P)...
June 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/28641680/ophthalmological-evaluation-of-integrated-resistance-and-aerobic-training-during-70-day-bed-rest
#2
Giovanni Taibbi, Ronita L Cromwell, Susana B Zanello, Patrice O Yarbough, Robert J Ploutz-Snyder, Bernard F Godley, Gianmarco Vizzeri
INTRODUCTION: We evaluated ophthalmic changes in healthy individuals who underwent integrated resistance and aerobic training (iRAT) during 70-d 6° head-down tilt (HDT) bed rest (BR). METHODS: Participants were selected using NASA standard screening procedures. Standardized NASA BR conditions were implemented. Subjects were randomly assigned to the iRAT protocol or no exercise during HDTBR. Weekly ophthalmic examinations were performed in the sitting (pre/post-BR only) and HDT (BR only) positions...
July 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28632847/pattern-recognition-analysis-of-age-related-retinal-ganglion-cell-signatures-in-the-human-eye
#3
Nayuta Yoshioka, Barbara Zangerl, Lisa Nivison-Smith, Sieu K Khuu, Bryan W Jones, Rebecca L Pfeiffer, Robert E Marc, Michael Kalloniatis
Purpose: To characterize macular ganglion cell layer (GCL) changes with age and provide a framework to assess changes in ocular disease. This study used data clustering to analyze macular GCL patterns from optical coherence tomography (OCT) in a large cohort of subjects without ocular disease. Methods: Single eyes of 201 patients evaluated at the Centre for Eye Health (Sydney, Australia) were retrospectively enrolled (age range, 20-85); 8 × 8 grid locations obtained from Spectralis OCT macular scans were analyzed with unsupervised classification into statistically separable classes sharing common GCL thickness and change with age...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28632031/mr-imaging-of-the-anterior-visual-pathway-in-primary-open-angle-glaucoma-correlation-with-octopus-101-perimetry-and-spectralis-optical-coherence-tomography-findings
#4
Mehmet Giray Ersoz, Yeliz Pekcevik, Emre Ayintap, İrfan Botan Gunes, Duygu Kunak Mart, Ersin Yucel, Gamze Türe
PURPOSE: To investigate structural changes in the visual pathway measured by magnetic resonance imaging (MRI) and its relationship with the clinical severity of glaucoma in primary open-angle glaucoma (POAG) patients. MATERIALS AND METHODS: The study included 28 patients with POAG and 26 age- and sex-matched healthy volunteers. All the subjects underwent spectral domain optical coherence tomography (OCT) of the peripapillary retina nerve fiber layer (RNFL). The optic nerve diameter (OND), chiasma height (Ch), and lateral geniculate nucleus height (LGNh) were measured bilaterally using a 1...
February 28, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28630764/impact-of-b-scan-averaging-on-spectralis-optical-coherence-tomography-image-quality-before-and-after-cataract-surgery
#5
Dominika Podkowinski, Ehsan Sharian Varnousfaderani, Christian Simader, Hrvoje Bogunovic, Ana-Maria Philip, Bianca S Gerendas, Ursula Schmidt-Erfurth, Sebastian M Waldstein
BACKGROUND AND OBJECTIVE: To determine optimal image averaging settings for Spectralis optical coherence tomography (OCT) in patients with and without cataract. STUDY DESIGN/MATERIAL AND METHODS: In a prospective study, the eyes were imaged before and after cataract surgery using seven different image averaging settings. Image quality was quantitatively evaluated using signal-to-noise ratio, distinction between retinal layer image intensity distributions, and retinal layer segmentation performance...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28615022/correlation-of-retinal-nerve-fibre-layer-and-macular-thickness-with-serum-uric-acid-among-type-2-diabetes-mellitus
#6
Munisamy-Naidu Vinuthinee-Naidu, Embong Zunaina, Anuar Azreen-Redzal, Naing Nyi-Nyi
BACKGROUND: Uric acid is a final breakdown product of purine catabolism in humans. It's a potent antioxidant and can also act as a pro-oxidant that induces oxidative stress on the vascular endothelial cells, thus mediating progression of diabetic related diseases. Various epidemiological and experimental evidence suggest that uric acid has a role in the etiology of type 2 diabetes mellitus. We conducted a cross-sectional study to evaluate the correlation of retinal nerve fibre layer (RNFL) and macular thickness with serum uric acid in type 2 diabetic patients...
June 14, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28608030/intracorneal-ring-segment-depth-in-keratoconus-patients-a-long-term-follow-up-study
#7
Saied Shahhoseini, Hassan Hashemi, Soheila Asgari
PURPOSE: To compare the actual depth of the tunnel created with femtosecond laser for intracorneal ring segment (ICRS) implantation with the target depth in keratoconus patients. METHODS: In this mix design study, eligible keratoconus patients were identified through chart review. The inclusion criterion was a history of ICRS implantation with femtosecond laser more than 6 months prior to enrollment. Participants underwent anterior segment optical coherence tomography using Spectralis (Heidelberg Engineering GmbH, Heidelberg, Germany) for depth measurement defined as the distance from the anterior corneal surface to anterior rim of the ring...
June 12, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28588646/the-effects-of-tolterodine-on-anterior-segment-and-choroidal-thickness-in-patients-with-overactive-bladder-syndrome
#8
Hande Hüsniye Telek, Omer Gokhan Doluoglu, Ayse Burcu, Gulizar Demirok, Firdevs Ornek, Ali Ayyildiz
BACKGROUND: To evaluate the effects of tolterodine on anterior segment and choroidal thickness by using the Pentacam system and optical coherence tomography (OCT) (Pentacam). METHODS: A total of 122 eyes of 61 patients (34 female; 27 male) were included in the study. All patients underwent a regular ocular examination and intraocular pressure measurements before and after 3 months of antimuscarinic drug tolterodine treatment, in addition, pupil diameter, anterior chamber depth, anterior chamber volume, anterior chamber angle, and lens thickness were measured through Pentacam (Oculus Inc...
October 2017: Therapeutic Advances in Urology
https://www.readbyqxmd.com/read/28574923/evaluation-of-patchy-atrophy-secondary-to-high-myopia-by-semiautomated-software-for-fundus-autofluorescence-analysis
#9
Alexandra Miere, Vittorio Capuano, Rita Serra, Camille Jung, Eric Souied, Giuseppe Querques
PURPOSE: To evaluate the progression of patchy atrophy in high myopia using semiautomated software for fundus autofluorescence (FAF) analysis. METHODS: The medical records and multimodal imaging of 21 consecutive highly myopic patients with macular chorioretinal patchy atrophy (PA) were retrospectively analyzed. All patients underwent repeated fundus autofluorescence and spectral domain optical coherence tomography over at least 12 months. Color fundus photography was also performed in a subset of patients...
May 31, 2017: Retina
https://www.readbyqxmd.com/read/28564701/the-impact-of-lens-opacity-on-sd-oct-retinal-nerve-fiber-layer-and-bruch-s-membrane-opening-measurements-using-the-anatomical-positioning-system-aps
#10
Matthias M Mauschitz, Felix Roth, Frank G Holz, Monique M B Breteler, Robert P Finger
Purpose: To evaluate the impact of lens opacity on retinal nerve fiber layer thickness (RNFLT) and Bruch's membrane opening (BMO) measurements. Methods: Fifty-nine randomly selected patients without any other relevant ocular pathology undergoing elective routine cataract surgery in two specialized eye clinics were enrolled. RNFLT, BMO area, and BMO minimum rim width (BMO-MRW) were assessed with the Heidelberg Engineering Spectralis OCT using the anatomical positioning system (APS) prior to and 1 day after cataract surgery using a ring scan at different eccentricities of the disc (3...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28560468/-ultra-widefield-angiography-for-retinal-vein-occlusion-how-large-is-large-enough
#11
M Storch, S Bemme, M Rehak, H Hoerauf, N Feltgen
BACKGROUND: The introduction of full fundus angiography (FAG) for retinal vein occlusion (RVO) has enriched diagnostic imaging; however, it is unclear how much of the retina has to be visualized to evaluate the risk of neovascularization. We investigated the 102° Spectralis camera to assess if imaging beyond the central 102° is necessary. METHODS: In this retrospective study we assessed 80 eyes of 80 patients with RVO to analyze central and peripheral ischemia using the ultra-widefield 102° Spectralis camera...
May 30, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28559725/green-laser-induced-foveal-cyst-sustained-in-a-recreational-laser-light-show
#12
Rukiye Aydin, Merve Ozbek, Mustafa Ozsutcu, Fevzi Senturk
We report the case of a 9-year-old boy complained of visual loss in his right eye after watching green laser light show being hit by a ray of a laser at shopping center before five days ago. The laser had a maximum power rating of 30 mW (US Food and Drug Administration class IIIB). Best-corrected visual acuity in his right eye was 0.2 with Snellen at 5 days after the injury. Dilated fundoscopic examination demonstrated a macular hole appearance in the right eye. Spectral domain optical coherence tomography (OCT, Spectralis, Heidelberg Engineering, Heidelberg, Germany) demonstrates a steep fovea contour, a thickening of the macular edges, intraretinal cysts, disruption of the photoreceptor inner segment/outer segment layer and macular pseudohole formation...
April 2017: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/28541963/correlation-of-structural-and-functional-outcome-measures-in-a-phase-one-trial-of-ciliary-neurotrophic-factor-in-type-2-idiopathic-macular-telangiectasia
#13
Ferenc B Sallo, Irene Leung, Traci E Clemons, Tunde Peto, Emily Y Chew, Daniel Pauleikhoff, Alan C Bird
PURPOSE: Macular telangiectasia Type 2 is a bilateral, progressive, potentially blinding retinal disease characterized by both vascular and neurodegenerative signs. Both the area of the break in the ellipsoid zone seen in "en face" optical coherence tomographic (OCT) images and microperimetric focal retinal sensitivity loss have been proposed as potential measures of progression in macular telangiectasia. The authors aimed to assess the characteristics and interrelationship of these structural and functional disease markers from the data collected in a phase one clinical trial of ciliary neurotrophic factor in macular telangiectasia...
May 23, 2017: Retina
https://www.readbyqxmd.com/read/28538221/retinal-microvasculature-in-nonproliferative-diabetic-retinopathy-automated-quantitative-optical-coherence-tomography-angiography-assessment
#14
Marco Lupidi, Gabriel Coscas, Florence Coscas, Tito Fiore, Elisa Spaccini, Daniela Fruttini, Carlo Cagini
PURPOSE: To perform a qualitative and quantitative assessment of the foveal microvasculature in eyes with diabetic maculopathy using optical coherence tomography angiography (OCT-A). METHODS: Retrospective case series of 48 eyes with diabetic maculopathy and 47 healthy eyes evaluated by Spectralis OCT-A. Perifoveal arcade disruptions, linear vascular dilations, microaneurysms, intraretinal microvascular abnormalities and flow-void areas were qualitatively analyzed on OCT angiograms both for the superficial (SCP) and deep (DCP) capillary plexuses...
May 25, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/28499747/preoperative-posturing-of-patients-with-macula-on-retinal-detachment-reduces-progression-toward-the-fovea
#15
Jan H de Jong, Juan P Vigueras-Guillén, Tiarah C Simon, Reinier Timman, Tunde Peto, Koenraad A Vermeer, Jan C van Meurs
PURPOSE: Traditionally, preoperative posturing consisting of bed rest and positioning is prescribed to patients with macula-on retinal detachment (RD) to prevent RD progression and detachment of the fovea. Execution of such advice can be cumbersome and expensive. This study aimed to investigate if preoperative posturing affects the progression of RD. DESIGN: Prospective cohort study. PARTICIPANTS: Ninety-eight patients with macula-on RD were included...
May 9, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28493982/comparison-of-spectral-domain-optical-coherence-tomography-for-intra-retinal-layers-thickness-measurements-between-healthy-and-diabetic-eyes-among-chinese-adults
#16
Shu-Ting Li, Xiang-Ning Wang, Xin-Hua Du, Qiang Wu
PURPOSE: To compare intra-retinal layer thickness measurements between eyes with no or mild diabetic retinopathy (DR) and age-matched controls using Spectralis spectral-domain optical coherence tomography (SD-OCT). METHODS: Cross-sectional observational analysis study. High-resolution macular volume scans (30° * 25°) were obtained for 133 type 2 diabetes mellitus (T2DM) patients with no DR, 42 T2DM patients with mild DR and 115 healthy controls. The mean thickness was measured in all 9 Early Treatment Diabetic Retinopathy Study (ETDRS) sectors for 8 separate layers, inner retinal layer (IRL), outer retinal layer (ORL) and total retina (TR), after automated segmentation...
2017: PloS One
https://www.readbyqxmd.com/read/28490427/effect-of-acute-intraocular-pressure-elevation-on-the-minimum-rim-width-in-normal-ocular-hypertensive-and-glaucoma-eyes
#17
Sourabh Sharma, Tin A Tun, Mani Baskaran, Eray Atalay, Sri Gowtham Thakku, Zhang Liang, Dan Milea, Nicholas G Strouthidis, Tin Aung, Michael Ja Girard
BACKGROUND: To estimate and compare changes in the Bruch's membrane opening-minimum rim width (BMO-MRW) and area in normal, ocular hypertensive and glaucoma eyes following acute elevations in intraocular pressure (IOP). METHODS: The optic nerve heads (ONHs) of 104 subjects (31 normals, 20 ocular hypertension (OHT) and 53 with primary glaucoma) were imaged using Spectral-domain optical coherence tomography (OCT; Spectralis, Heidelberg Engineering, Germany). IOP was raised twice by applying a force (0...
May 10, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28489918/oct-angiography-a-qualitative-and-quantitative-comparison-of-4-oct-a-devices
#18
Marion R Munk, Helena Giannakaki-Zimmermann, Lieselotte Berger, Wolfgang Huf, Andreas Ebneter, Sebastian Wolf, Martin S Zinkernagel
PURPOSE: To compare the quality of four OCT-angiography(OCT-A) modules. METHOD: The retina of nineteen healthy volunteers were scanned with four OCT-devices (Topcon DRI-OCT Triton Swept-source OCT, Optovue RTVue-XR, a prototype Spectralis OCT2, Heidelberg-Engineering and Zeiss Cirrus 5000-HD-OCT). The device-software generated en-face OCT-A images of the superficial (SCP) and deep capillary plexuses (DCP) were evaluated and scored by 3 independent retinal imaging experts...
2017: PloS One
https://www.readbyqxmd.com/read/28461015/diagnostic-accuracy-of-spectralis-sd-oct-automated-macular-layers-segmentation-to%C3%A2-discriminate-normal-from-early-glaucomatous-eyes
#19
Marta Pazos, Agnieszka Anna Dyrda, Marc Biarnés, Alicia Gómez, Carlos Martín, Clara Mora, Gianluca Fatti, Alfonso Antón
PURPOSE: To evaluate the accuracy of the macular retinal layer segmentation software of the Spectralis spectral-domain (SD) optical coherence tomography (OCT) device (Heidelberg Engineering, Inc., Heidelberg, Germany) to discriminate between healthy and early glaucoma (EG) eyes. DESIGN: Prospective, cross-sectional study. PARTICIPANTS: Forty EG eyes and 40 healthy controls were included. METHODS: All participants were examined using the standard posterior pole and the peripapillary retinal nerve fiber layer (pRNFL) protocols of the Spectralis OCT device...
April 28, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28430332/relationship-between-corneal-biomechanical-properties-and-optic-nerve-head-changes-after-deep-sclerectomy
#20
Laura Díez-Álvarez, Francisco J Muñoz-Negrete, Pilar Casas-Llera, Noelia Oblanca, Victoria de Juan, Gema Rebolleda
PURPOSE: To evaluate corneal biomechanical properties and optic nerve head (ONH) changes following deep sclerectomy (DS) and the relation to each other. METHODS: Forty-nine eyes with primary open-angle glaucoma that underwent DS were studied. Corneal biomechanical properties were assessed using the Ocular Response Analyzer and the ONH was evaluated by Spectralis optical coherence tomography with enhanced depth imaging technology before surgery and 3 months postoperatively...
April 4, 2017: European Journal of Ophthalmology
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