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https://www.readbyqxmd.com/read/28100480/detection-of-posterior-vortex-veins-in-eyes-with-pathologic-myopia-by-ultra-widefield-indocyanine-green-angiography
#1
Muka Moriyama, Kejia Cao, Satoko Ogata, Kyoko Ohno-Matsui
AIMS: To analyse the characteristics of posterior vortex veins detected in highly myopic eyes by wide-field indocyanine green angiography (ICGA). METHODS: One hundred and fifty-eight consecutive patients (302 eyes) with high myopia (myopic refractive error >8.0 dioptres (D) or axial length ≥26.5 mm) were studied. Wide-field ICGA was performed with the Spectralis HRA module. RESULTS: Posterior vortex veins were found in 80 eyes (26%)...
January 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28092396/agreement-between-three-optical-coherence-tomography-devices-to-assess-the-insertion-distance-and-thickness-of-horizontal-rectus-muscles
#2
Lucía De-Pablo-Gómez-de-Liaño, José Ignacio Fernández-Vigo, Néstor Ventura-Abreu, Julián García-Feijóo, José Ángel Fernández-Vigo, Rosario Gómez-de-Liaño
PURPOSE: To assess the agreement between two different spectral domain (SD-OCT) and one swept source (SS-OCT) optical coherence tomography device to measure the insertion distance and the thickness of the horizontal rectus muscles. METHODS: Seventy eyes from 35 healthy patients were studied. Three OCT instruments-Spectralis (Heidelberg Engineering Inc., Heidelberg, Germany), Cirrus 5000 (Carl Zeiss Meditec, Dublin, CA), and Triton (Topcon, Inc., Tokyo, Japan)-were used to measure the limbus insertion distance and the thickness of the lateral rectus and medial rectus muscles...
January 13, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28069281/-effect-of-donor-graft-characteristics-on-clinical-outcomes-in-descemet-stripping-automated-endothelial-keratoplasty-dsaek
#3
G Ho Wang Yin, M Sampo, S Soare, L Hoffart
INTRODUCTION: The purpose of our study was to evaluate the progression of lamellar corneal grafts after endothelial keratoplasty by Descemet stripping automated endothelial keratoplasty (DSAEK) and the effect of their characteristics on the clinical and functional results. MATERIALS AND METHODS: This was a prospective study in which 74 patients who had undergone endothelial keratoplasty by DSAEK were included. The corneal grafts were obtained from a French tissue bank and were delivered in a preservation medium containing a deturgescent agent (Corneajet(®) or Stemalpha 3(®))...
January 6, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28068388/the-association-between-foveal-morphology-and-macular-pigment-spatial-distribution-an-ethnicity-study
#4
Irene Ctori, Byki Huntjens
PURPOSE: Macular pigment (MP) spatial distribution varies considerably among individuals. We investigated ethnic variations in MP spatial distribution in relation to foveal architecture. METHODS: We measured MP optical density (MPOD) using heterochromatic flicker photometry (MAP test, City, University of London) in 76 white, 80 South Asian and 70 black volunteers (18 to 39 years). MPOD spatial profiles were classified objectively as exponential, ring-like or central dip, based on deviations away from an exponential fit...
2017: PloS One
https://www.readbyqxmd.com/read/28060065/lower-tear-meniscus-measurements-using-a-new-anterior-segment-swept-source-optical-coherence-tomography-and-agreement-with-fourier-domain-optical-coherence-tomography
#5
Pedro Arriola-Villalobos, José Ignacio Fernández-Vigo, David Díaz-Valle, Jaime Almendral-Gómez, Cristina Fernández-Pérez, José M Benítez-Del-Castillo
PURPOSE: To assess intraobserver repeatability and interobserver and intersession reproducibility of lower tear meniscus height (LTMH) measurements obtained using a new anterior segment swept-source optical coherence tomography (SS-OCT) device. Agreement with Fourier-domain (FD) OCT (Spectralis) was also examined. METHODS: In an observational cross-sectional study, one eye of 29 healthy subjects was randomly imaged with both devices at our center. Two examiners then randomly measured the LTMH using the software's calipers...
February 2017: Cornea
https://www.readbyqxmd.com/read/28052542/impact-of-retinal-pigment-epithelium-pathology-on-spectral-domain-optical-coherence-tomography-derived-macular-thickness-and-volume-metrics-and-their-intersession-repeatability
#6
Daren Hanumunthadu, Jin Ping Wang, Wei Chen, Evan N Wong, Yi Chen, William H Morgan, Praveen J Patel, Fred K Chen
BACKGROUND: To determine the impact of retinal pigment epithelium (RPE) pathology on intersession repeatability of retinal thickness and volume metrics derived from Spectralis spectral-domain optical coherence tomography (Heidelberg Engineering, Heidelberg, Germany). DESIGN: Prospective cross-sectional single centre study. PARTICIPANTS: A total of 56 eyes of 56 subjects were divided into three groups: (i) normal RPE band (25 eyes); (ii) RPE elevation: macular soft drusen (13 eyes); and (iii) RPE attenuation: geographic atrophy or inherited retinal diseases (18 eyes)...
November 6, 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28033232/choroidal-thickness-changes-after-vitrectomy-with-silicone-oil-tamponade-for-proliferative-vitreoretinopathy-retinal-detachment
#7
Dominik Odrobina, Joanna Gołębiewska, Iwona Maroszyńska
PURPOSE: To access the potential effect of vitrectomy and silicone oil tamponade on the choroid. METHODS: Eighteen patients (18 eyes) who had undergone pars plana vitrectomy with 1,000-cSt silicone oil tamponade for proliferative vitreoretinopathy retinal detachment were included in this retrospective study. All patients underwent ophthalmologic examinations before treatment and 1 week and 1, 3, and 6 months after vitrectomy with silicone oil tamponade. Choroidal thickness was measured using enhanced depth imaging optical coherence tomography (Spectralis; Heidelberg Engineering) in a horizontal and vertical section beneath the fovea...
December 28, 2016: Retina
https://www.readbyqxmd.com/read/28030536/effect-of-refractive-correction-error-on-retinal-nerve-fiber-layer-thickness-a-spectralis-optical-coherence-tomography-study
#8
Xiaoli Ma, Yutong Chen, Xianjie Liu, Hong Ning
BACKGROUND Identifying and assessing retinal nerve fiber layer defects are important for diagnosing and managing glaucoma. We aimed to investigate the effect of refractive correction error on retinal nerve fiber layer (RNFL) thickness measured with Spectralis spectral-domain optical coherence tomography (SD-OCT). MATERIAL AND METHODS We included 68 participants: 32 healthy (normal) and 36 glaucoma patients. RNFL thickness was measured using Spectralis SD-OCT circular scan. Measurements were made with a refractive correction of the spherical equivalent (SE), the SE+2...
December 28, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28029231/measurement-of-lacrimal-punctum-using-spectralis-domain-anterior-optical-coherence-tomography
#9
Youngje Sung, Jong Seo Park, Helen Lew
PURPOSE: Anterior segment optical coherence tomography (AS-OCT) was used to image the lacrimal punctum and establish normal punctal parameters including the tear volume inside the punctum. METHODS: This study included totally 67 eyes from 38 normal subjects. Punctal parameters and tear meniscus height (TMH) were measured using spectralis OCT anterior-segment scans. Outer punctal diameter (OPD), punctal depth, tear well diameter (TWD), tear well depth, punctal reserve (PR) and lower eyelid TMH were assessed...
December 28, 2016: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28009402/choroidal-characteristics-of-acute-and-chronic-central-serous-chorioretinopathy-using-enhanced-depth-imaging-optical-coherence-tomography
#10
Jorge Ruiz-Medrano, Marco Pellegrini, Matteo G Cereda, Mario Cigada, Giovanni Staurenghi
PURPOSE: Central serous chorioretinopathy (CSC) is an idiopathic disorder characterized by serous detachments of the neurosensory retina and/or the retinal pigment epithelium affecting the macular area in the majority of cases. The objective of this study was to describe choroidal findings in patients with acute and chronic CSC based on enhanced depth imaging optical coherence tomography analysis. METHODS: This is a cross-sectional, noninterventional study performed at Luigi Sacco University Hospital of Milan...
November 18, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28005632/association-between-the-vitreomacular-interface-and-optical-coherence-tomography-characteristics-in-wet-age-related-macular-degeneration
#11
Mohammed Ashraf, Ahmed Souka, Ron A Adelman
PURPOSE: To study the effect of the vitreomacular interface on various wet age-related macular degeneration (AMD) characteristics including the size and type of choroidal neovascularization (CNV), choroidal thickness, and activity of the CNV. METHODS: This was a retrospective observational cross-sectional study. The study included 43 patients (51 eyes) with treatment-naive age-related macular degeneration. Twenty-six patients with wet AMD in one eye and dry AMD in the other eye were included in a paired-eye analysis...
December 21, 2016: Retina
https://www.readbyqxmd.com/read/27990369/macular-changes-of-neuromyelitis-optica-through-spectral-domain-optical-coherence-tomography
#12
Lu Cheng, Jing Wang, Xu He, Xun Xu, Zhen-Fen Ling
AIM: To evaluate the thickness of the retinal layers in the macula using spectral-domain optical coherence tomography (SD-OCT) in patients with neuromyelitis optica (NMO). METHODS: Spectralis SD-OCT, utilizing automated macular layer segmentation, was performed in 26 NMO patients and 26 healthy controls. Visual function including visual field tests and pattern visual evoked potential were recorded in study subjects. RESULTS: Forty-one eyes from 26 NMO patients and 52 eyes from 26 age- and sex-matched healthy controls were included...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27942587/chorioretinal-thinning-in-chronic-kidney-disease-links-to-inflammation-and-endothelial-dysfunction
#13
Craig Balmforth, Job J M H van Bragt, Titia Ruijs, James R Cameron, Robert Kimmitt, Rebecca Moorhouse, Alicja Czopek, May Khei Hu, Peter J Gallacher, James W Dear, Shyamanga Borooah, Iain M MacIntyre, Tom M C Pearson, Laura Willox, Dinesh Talwar, Muriel Tafflet, Christophe Roubeix, Florian Sennlaub, Siddharthan Chandran, Baljean Dhillon, David J Webb, Neeraj Dhaun
BACKGROUND. Chronic kidney disease (CKD) is strongly associated with cardiovascular disease and there is an established association between vasculopathy affecting the kidney and eye. Optical coherence tomography (OCT) is a novel, rapid method for high-definition imaging of the retina and choroid. Its use in patients at high cardiovascular disease risk remains unexplored. METHODS. We used the new SPECTRALIS OCT machine to examine retinal and retinal nerve fiber layer (RNFL) thickness, macular volume, and choroidal thickness in a prospective cross-sectional study in 150 subjects: 50 patients with hypertension (defined as a documented clinic BP greater than or equal to 140/90 mmHg (prior to starting any treatment) with no underlying cause identified); 50 with CKD (estimated glomerular filtration rate (eGFR) 8-125 ml/min/1...
December 8, 2016: JCI Insight
https://www.readbyqxmd.com/read/27941529/change-of-choroidal-volume-in-untreated-central-serous-chorioretinopathy
#14
Laura Pertl, Anton Haas, Silke Hausberger, Tamara Pichler, Dieter F Rabensteiner, Gerald Seidel, Eva M Malle, Martin Weger
PURPOSE: Choroidal hyperpermeability plays a central role in the pathophysiology of central serous chorioretinopathy (CSC). In active CSC undergoing treatment, choroidal thickness decreases if subretinal fluid (SRF) resolves. This study aimed to investigate the change in choroidal thickness and volume in eyes with untreated CSC. METHODS: The authors retrospectively analyzed 27 eyes with treatment-naïve CSC (25 patients), who had a follow-up of 4 to 6 weeks. Retinal and choroidal volume and SRF were segmented manually and calculated using the Spectralis OCT built-in software (Spectralis; Heidelberg Engineering)...
December 9, 2016: Retina
https://www.readbyqxmd.com/read/27935604/ocular-characteristics-associated-with-the-location-of-focal-lamina-cribrosa-defects-in-open-angle-glaucoma-patients
#15
H-Yl Park, Y S Hwang, C K Park
PurposeTo investigate the clinical characteristics according to the location of focal lamina cribrosa (LC) defects and its associated ocular features.Patients and methodsA total of 139 open-angle glaucoma patients underwent Spectralis optical coherence tomography (OCT) with enhanced depth imaging. Alterations in the contour of the LC were investigated to find focal LC defects. The location of the visible LC defect from the neural canal wall (far-peripheral and mid-peripheral) and clock-hour position (superotemporal, temporal and inferotemporal) were classified...
December 9, 2016: Eye
https://www.readbyqxmd.com/read/27930457/novel-findings-on-optical-coherence-tomography-angiography-in-patients-with-tubercular-serpiginous-like-choroiditis
#16
Spoorti Krishna Reddy Mandadi, Aniruddha Agarwal, Kanika Aggarwal, Bruttendu Moharana, Ramandeep Singh, Aman Sharma, Reema Bansal, Mangat R Dogra, Vishali Gupta
PURPOSE: To analyze and describe the imaging characteristics of tubercular serpiginous-like choroiditis using optical coherence tomography angiography (OCTA) and to compare these findings with multimodal imaging. METHODS: In this prospective cross-sectional study, multimodal imaging was performed in subjects with tubercular serpiginous-like choroiditis using OCTA (Optovue RTVue XR Avanti), enhanced-depth imaging OCT (Heidelberg Spectralis), fundus autofluorescence, fluorescein angiography, and indocyanine green angiography...
December 7, 2016: Retina
https://www.readbyqxmd.com/read/27915343/intravitreal-dexamethasone-implant-for-the-treatment-of-postoperative-macular-edema
#17
André Klamann, Katharina Böttcher, Philipp Ackermann, Gerd Geerling, Marc Schargus, Rainer Guthoff
INTRODUCTION: Macular edema after cataract surgery (Irvine-Gass syndrome) or pars plana vitrectomy is a postoperative complication which can lead to permanent visual loss. Increased inflammatory substances, such as prostaglandins and cytokines, are discussed to be causative. Currently, there are no evidence-based guidelines for the treatment of postoperative macular edema. Intravitreal dexamethasone (DEX) could be effective by its anti-inflammatory effect. We examined the functional and morphological results of treatment with 0...
2016: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/27893521/lower-tear-meniscus-measurements-using-a-new-anterior-segment-swept-source-optical-coherence-tomography-and-agreement-with-fourier-domain-optical-coherence-tomography
#18
Pedro Arriola-Villalobos, José Ignacio Fernández-Vigo, David Díaz-Valle, Jaime Almendral-Gómez, Cristina Fernández-Pérez, José M Benítez-Del-Castillo
PURPOSE: To assess intraobserver repeatability and interobserver and intersession reproducibility of lower tear meniscus height (LTMH) measurements obtained using a new anterior segment swept-source optical coherence tomography (SS-OCT) device. Agreement with Fourier-domain (FD) OCT (Spectralis) was also examined. METHODS: In an observational cross-sectional study, one eye of 29 healthy subjects was randomly imaged with both devices at our center. Two examiners then randomly measured the LTMH using the software's calipers...
November 23, 2016: Cornea
https://www.readbyqxmd.com/read/27867714/automatic-identification-of-the-temporal-retinal-nerve-fiber-raphe-from-macular-cube-data
#19
Phillip Bedggood, Fumi Tanabe, Allison M McKendrick, Andrew Turpin
We evaluated several approaches for automatic location of the temporal nerve fiber raphe from standard macular cubes acquired on a Heidelberg Spectralis OCT. Macular cubes with B-scan separation of 96-122 µm were acquired from 15 healthy participants, and "high density" cubes with scan separation of 11 µm were acquired from the same eyes. These latter scans were assigned to experienced graders for subjective location of the raphe, providing the ground truth by which to compare methods operating on the lower density data...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27864062/en-face-optical-coherence-tomography-imaging-for-the-detection-of-nascent-geographic-atrophy
#20
Karen B Schaal, Giovanni Gregori, Philip J Rosenfeld
PURPOSE: To determine if en face optical coherence tomography (OCT) imaging can identify nascent geographic atrophy (nGA) in eyes with intermediate age-related macular degeneration (iAMD). DESIGN: Retrospective observational case series. METHODS: Patients with iAMD from the COMPLETE study at the Bascom Palmer Eye Institute were evaluated to determine if nGA was present at baseline and at follow-up using high-density Spectralis OCT B-scans and en face OCT images from the Cirrus OCT instrument...
February 2017: American Journal of Ophthalmology
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