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https://www.readbyqxmd.com/read/28321986/monitoring-retinoschisis-and-non-acute-retinal-detachment-by-optical-coherence-tomography-morphologic-aspects-and-clinical-impact
#1
Katharina Eibenberger, Stefan Sacu, Sandra Rezar-Dreindl, Julia Pöcksteiner, Michael Georgopoulos, Ursula Schmidt-Erfurth
PURPOSE: To differentiate retinoschisis (RS) from non-acute retinal detachment (naRD) in clinical routine using optical coherence tomography (OCT), describe unique morphological OCT characteristics and monitor disease progression. METHODS: This prospective, observational study included 64 eyes of 44 patients with either RS or naRD. Patients were examined clinically and using Heidelberg Spectralis OCT(®) , Topcon DRI OCT(®) and Cirrus HRA-OCT(®) over 2 years with follow-up at 1, 3, 6, 12 and 24 months...
March 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28315514/optic-nerve-head-in-central-retinal-vein-occlusion-by-spectral-domain-oct
#2
Antonio Longo, Teresio Avitabile, Maurizio G Uva, Vincenza Bonfiglio, Andrea Russo, Mario D Toro, Caterina Gagliano, Matteo Fallico, Michele Reibaldi
PURPOSE: To evaluate the morphology of optic nerve head by spectral-domain optical coherence tomography (SD-OCT) in patients with unilateral central retinal vein occlusion (CRVO). METHODS: In 39 consecutive patients with unilateral CRVO and 39 healthy controls, morphologic parameters of optic nerve head were assessed in both eyes by Spectralis SD-OCT using a custom radial B-scan pattern. The length of Bruch membrane opening (BMO) was measured in OCT scans, and optic disc diameters (DD) were assessed in infrared fundus photographs...
February 28, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28301411/retinal-phenotype-in-a-case-of-lchad-tfp-deficiency-with-late-stage-diagnosis
#3
Jacob A Knowles, Ioannis S Dimopoulos, Ian M MacDonald
PURPOSE: To report the retinal phenotype of a rare case of long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD)/trifunctional protein (TFP) deficiency diagnosed in his late 40s with ocular findings of diffuse chorioretinal atrophy and bilateral retinoschisis. METHODS: An acylcarnitine profile assay revealed LCHAD/TFP deficiency in a 45-year-old man with a history of high myopia, bilateral decreased vision, episodic rhabdomyolysis, and peripheral neuropathy. Ocular findings were evaluated with spectral domain optical coherence tomography (Spectralis OCT; Heidelberg Engineering, Heidelberg, Germany) and color fundus photography...
March 15, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28297035/short-term-effects-of-early-switching-to-ranibizumab-or-aflibercept-in-diabetic-macular-edema-cases-with-non-response-to-bevacizumab
#4
Mohammed Ashraf, Ahmed A R Souka, Hassan ElKayal
BACKGROUND AND OBJECTIVES: To study the effect of early switching to ranibizumab (Lucentis; Genentech, South San Francisco, CA) or aflibercept (Eylea; Regeneron, Tarrytown, NY) in cases of diabetic macular edema (DME) that have shown no response to bevacizumab (Avastin; Genentech, South San Francisco, CA). PATIENTS AND METHODS: A retrospective study involving 59 eyes of 45 patients with DME previously treated with bevacizumab. Patients were switched either to ranibizumab or aflibercept...
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28277878/effect-of-smoking-on-the-thickness-of-retinal-layers-in-healthy-smokers
#5
Rahmi Duman, Reşat Duman, Mehmet Cem Sabaner, Ersan Çetinkaya
PURPOSE: To compare the thicknesses of the retinal layers in smokers with those of non smoking healthy subjects using spectral-domain optical coherence tomography (SD-OCT). METHODS: One hundred and eight subjects were included in the study. Two groups were separated as smokers and non-smokers. Both groups were chosen to be similar in terms of age and gender. SD-OCT images were generated with Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). An automated algorithm was developed to segment the macular retina into eight layers and quantitate the thickness of each layer for the fovea, parafovea and perifovea...
March 3, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28277440/abnormal-vascular-complex-within-an-idiopathic-epiretinal-membrane-imaged-by-optical-coherence-tomography-angiography
#6
Sacha Gueunoun, Gabriela Nazim, Elsa Bruyère, André Sieiro, Eric H Souied, Alexandra Miere
PURPOSE: To report the case 70-year-old patient presenting with preretinal, abnormal vascularization accompanying an idiopathic epiretinal membrane (ERM), identified by optical coherence tomography angiography. METHODS: Observational case report of one patient. RESULTS: The authors describe the case of a patient presenting with an ERM on the right eye since March 2011, diagnosed by fundus biomicroscopy and spectral domain optical coherence tomography (Spectralis; Heidelberg Engineering, Heidelberg, Germany)...
March 8, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28275528/signal-normalization-reduces-image-appearance-disparity-among-multiple-optical-coherence-tomography-devices
#7
Chieh-Li Chen, Hiroshi Ishikawa, Gadi Wollstein, Richard A Bilonick, Larry Kagemann, Joel S Schuman
PURPOSE: To assess the effect of the previously reported optical coherence tomography (OCT) signal normalization method on reducing the discrepancies in image appearance among spectral-domain OCT (SD-OCT) devices. METHODS: Healthy eyes and eyes with various retinal pathologies were scanned at the macular region using similar volumetric scan patterns with at least two out of three SD-OCT devices at the same visit (Cirrus HD-OCT, Zeiss, Dublin, CA; RTVue, Optovue, Fremont, CA; and Spectralis, Heidelberg Engineering, Heidelberg, Germany)...
February 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28265747/the-effect-of-allergic-rhinitis-with-positive-skin-prick-test-on-choroidal-thickness
#8
Alper Yenigun, Ahmet Elbay, Remzi Dogan, Orhan Ozturan, Mehmet Hakan Ozdemir
Allergic rhinitis is an inflammatory disease that develops through immunoglobulin E in the rhino-ocular mucosa due to allergy. The main symptoms are runny nose, nasal congestion, sneezing and itchy nose. This study was designed to investigate the effect of allergic rhinitis on choroidal thickness. This study was planned as a case-control study. This study performed in a tertiary referral center. The study included 61 patients with allergic rhinitis and 35 healthy subjects. Patients in both groups underwent skin prick test...
March 6, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28243926/comparing-three-different-modes-of-electroretinography-in-experimental-glaucoma-diagnostic-performance-and-correlation-to-structure
#9
Laura Wilsey, Sowjanya Gowrisankaran, Grant Cull, Christy Hardin, Claude F Burgoyne, Brad Fortune
PURPOSE: To compare diagnostic performance and structure-function correlations of multifocal electroretinogram (mfERG), full-field flash ERG (ff-ERG) photopic negative response (PhNR) and transient pattern-reversal ERG (PERG) in a non-human primate (NHP) model of experimental glaucoma (EG). METHODS: At baseline and after induction of chronic unilateral IOP elevation, 43 NHP had alternating weekly recordings of retinal nerve fiber layer thickness (RNFLT) by spectral domain OCT (Spectralis) and retinal function by mfERG (7F slow-sequence stimulus, VERIS), ff-ERG (red 0...
February 27, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28237425/aqueous-angiography-in-living-nonhuman-primates-shows-segmental-pulsatile-and-dynamic-angiographic-aqueous-humor-outflow
#10
Alex S Huang, Meng Li, Diya Yang, Huaizhou Wang, Ningli Wang, Robert N Weinreb
PURPOSE: To evaluate the feasibility of safely performing aqueous angiography in intact eyes of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental patterns. DESIGN: Cross-sectional, observational study. SUBJECTS: Six nonhuman primates. METHODS: Aqueous angiography was performed in 6 nonhuman primates. After anesthesia, an anterior chamber (AC) maintainer was placed through a temporal 1-mm side-port wound...
February 22, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28228830/optic-disc-and-macular-imaging-in-blind-eyes-from-non-glaucomatous-optic-neuropathy-a-study-with-spectral-domain-optical-coherence-tomography
#11
Linda Hansapinyo, Andy C O Cheng, Noel C Y Chan, Carmen K M Chan
The purpose of this study was to determine and compare the optic disc and macular thickness measurements using two spectral-domain optical coherence tomography (SD-OCT) instruments in long-standing blind eyes diagnosed with non-glaucomatous optic neuropathies (NGON). A prospective observational case-series design was used. Twelve eyes from 12 NGON patients with no light perception for at least 6 months underwent optic disc and macular imaging with Cirrus HD-OCT and Spectralis OCT. The correlation between the peripapillary retinal nerve fibre layer (PRNFL) and macular ganglion cell layer and inner plexiform layer (GCL+IPL) thicknesses, and between the duration of no light perception (NLP) and PRNFL/GCL+IPL thicknesses were determined using Spearman's correlation analysis...
February 2017: Neuro-ophthalmology
https://www.readbyqxmd.com/read/28207606/retinal-layer-segmentation-after-silicone-oil-or-gas-tamponade-for-macula-on-retinal-detachment-using-optical-coherence-tomography
#12
Sung Hoon Lee, Jong Wook Han, Suk Ho Byeon, Sung Soo Kim, Hyoung Jun Koh, Sung Chul Lee, Min Kim
PURPOSE: To evaluate and compare the effect of silicone oil and gas on the thickness of all retinal layers in eyes with macula-on retinal detachment (RD). METHODS: Three hundred and sixty-seven eyes of 367 patients who received silicone oil tamponade and 310 eyes of 310 patients who received gas tamponade for the treatment of rhegmatogenous RD were initially reviewed. Automated retinal segmentation method using Spectralis optical coherence tomography was used for analysis...
February 15, 2017: Retina
https://www.readbyqxmd.com/read/28205342/functional-benefits-and-patient-satisfaction-with-upper-blepharoplasty-evaluated-by-objective-and-subjective-outcome-measures
#13
Agnes Galbo Jacobsen, Brian Brost, Henrik Vorum, Janos Hargitai
PURPOSE: To investigate the functional benefits and patient satisfaction with upper blepharoplasty in patients meeting the Danish visitation guidelines for upper blepharoplasty from the Danish Health and Medicines Authority (Sundhedsstyrelsen). METHODS: Before and 3 months after upper blepharoplasty, the following investigations were made: (i) a standard eye examination, (ii) photographic documentation with a normal camera and the infrared camera of a Spectralis Optical Coherence Tomograph and (iii) measurements of the upper visual fields using the blepharoptosis test of Octopus 900...
February 15, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28180033/platform-independent-cirrus-and-spectralis-thickness-measurements-in-eyes-with-diabetic-macular-edema-using-fully-automated-software
#14
Alex S Willoughby, Stephanie J Chiu, Rachel K Silverman, Sina Farsiu, Clare Bailey, Henry E Wiley, Frederick L Ferris, Glenn J Jaffe
PURPOSE: We determine whether the automated segmentation software, Duke Optical Coherence Tomography Retinal Analysis Program (DOCTRAP), can measure, in a platform-independent manner, retinal thickness on Cirrus and Spectralis spectral domain optical coherence tomography (SD-OCT) images in eyes with diabetic macular edema (DME) under treatment in a clinical trial. METHODS: Automatic segmentation software was used to segment the internal limiting membrane (ILM), inner retinal pigment epithelium (RPE), and Bruch's membrane (BM) in SD-OCT images acquired by Cirrus and Spectralis commercial systems, from the same eye, on the same day during a clinical interventional DME trial...
February 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28171871/effect-of-photodynamic-therapy-on-optical-coherence-tomography-angiography-in-eyes-with-chronic-central-serous-chorioretinopathy
#15
Yishuang Xu, Yu Su, Lu Li, Hang Qi, Hongmei Zheng, Changzheng Chen
PURPOSE: To analyze the use of optical coherence tomography angiography (OCTA) in order to observe the changes in chronic central serous chorioretinopathy (CCSC) after half-dose photodynamic therapy (PDT). METHODS: This is a retrospective study evaluating an imaging technique in a cohort of patients. Fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICGA) (Heidelberg Spectralis, Heidelberg, Germany), OCT, and OCTA with the split-spectrum amplitude-decorrelation angiography algorithm (XR Optovue, Fremont, CA, USA) were performed prior to half-dose PDT...
February 8, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28133888/alterations-of-the-outer-retina-in-non-arteritic-anterior-ischemic-optic-neuropathy-detected-using-spectral-domain-optical-coherence-tomography
#16
Philipp Ackermann, Maike Brachert, Philipp Albrecht, Marius Ringelstein, David Finis, Gerd Geerling, Orhan Aktas, Rainer Guthoff
BACKGROUND: Changes in peripapillary and macular retinal layer thickness in non-arteritic anterior ischemic optic neuropathy (NAION) measured using spectral-domain optical coherence tomography may reflect a characteristic disease pattern. Advanced software enables retinal layer segmentation. In this study, we compared retinal layer thicknesses in acute and chronic NAION. DESIGN: A single-center cross-sectional analysis in a university clinic. PARTICIPANTS: 14 eyes with acute (<7 days) and 13 eyes with chronic NAION and 20 age-matched healthy eyes...
January 30, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28118204/can-glaucomatous-visual-field-progression-be-predicted-by-structural-and-functional-measures
#17
Wolfgang A Schrems, Laura-M Schrems-Hoesl, Christian Y Mardin, Robert Laemmer, Friedrich E Kruse, Folkert K Horn
PURPOSE: The aim of this study was to compare the predictive value of retinal nerve fiber layer thickness (RNFLT) measurements obtained by optical coherence tomography (OCT), morphometric parameters of confocal scanning laser ophthalmoscopy (CSLO), and frequency-doubling technique perimetry to predict visual field conversion of normal individuals, ocular hypertensive subjects, and early preperimetric glaucoma patients as determined by standard automated perimetry (SAP). PATIENTS AND METHODS: This longitudinal single-center study included 107 eyes of 56 controls, 164 eyes of 98 patients with ocular hypertension, and 169 eyes of 110 patients with preperimetric glaucoma...
January 23, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28100480/detection-of-posterior-vortex-veins-in-eyes-with-pathologic-myopia-by-ultra-widefield-indocyanine-green-angiography
#18
Muka Moriyama, Kejia Cao, Satoko Ogata, Kyoko Ohno-Matsui
AIMS: To analyse the characteristics of posterior vortex veins detected in highly myopic eyes by wide-field indocyanine green angiography (ICGA). METHODS: One hundred and fifty-eight consecutive patients (302 eyes) with high myopia (myopic refractive error >8.0 dioptres (D) or axial length ≥26.5 mm) were studied. Wide-field ICGA was performed with the Spectralis HRA module. RESULTS: Posterior vortex veins were found in 80 eyes (26%)...
January 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28092396/agreement-between-three-optical-coherence-tomography-devices-to-assess-the-insertion-distance-and-thickness-of-horizontal-rectus-muscles
#19
Lucía De-Pablo-Gómez-de-Liaño, José Ignacio Fernández-Vigo, Néstor Ventura-Abreu, Julián García-Feijóo, José Ángel Fernández-Vigo, Rosario Gómez-de-Liaño
PURPOSE: To assess the agreement between two different spectral domain (SD-OCT) and one swept source (SS-OCT) optical coherence tomography device to measure the insertion distance and the thickness of the horizontal rectus muscles. METHODS: Seventy eyes from 35 healthy patients were studied. Three OCT instruments-Spectralis (Heidelberg Engineering Inc., Heidelberg, Germany), Cirrus 5000 (Carl Zeiss Meditec, Dublin, CA), and Triton (Topcon, Inc., Tokyo, Japan)-were used to measure the limbus insertion distance and the thickness of the lateral rectus and medial rectus muscles...
January 13, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28069281/-effect-of-donor-graft-characteristics-on-clinical-outcomes-in-descemet-stripping-automated-endothelial-keratoplasty-dsaek
#20
G Ho Wang Yin, M Sampo, S Soare, L Hoffart
INTRODUCTION: The purpose of our study was to evaluate the progression of lamellar corneal grafts after endothelial keratoplasty by Descemet stripping automated endothelial keratoplasty (DSAEK) and the effect of their characteristics on the clinical and functional results. MATERIALS AND METHODS: This was a prospective study in which 74 patients who had undergone endothelial keratoplasty by DSAEK were included. The corneal grafts were obtained from a French tissue bank and were delivered in a preservation medium containing a deturgescent agent (Corneajet(®) or Stemalpha 3(®))...
January 6, 2017: Journal Français D'ophtalmologie
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