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https://www.readbyqxmd.com/read/28930883/reproducibility-and-agreement-of-anterior-segment-parameter-measurements-obtained-using-the-casia2-and-spectralis-oct2-optical-coherence-tomography-devices
#1
Benjamin Y Xu, Derek D Mai, Rafaella C Penteado, Luke Sanders, Robert N Weinreb
PURPOSE: To assess the reproducibility and agreement of measurement values obtained from the Tomey CASIA2 and Heidelberg Spectralis OCT2 anterior segment optical coherence tomography (AS-OCT) devices. METHODS: Twenty eyes from ten subjects ranging from age 28 to 45 years with no history of eye conditions or intraocular surgery were included. Two scans were obtained with each device in a standardized dark-room environment after a period of dark adaptation. One AS-OCT image along the horizontal (temporal-nasal) meridian was analyzed per eye and per scan...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28930882/reproducibility-of-bruch-s-membrane-opening-minimum-rim-width-measurements-with-spectral-domain-optical-coherence-tomography
#2
Keunheung Park, Jinmi Kim, Jiwoong Lee
PURPOSE: To evaluate the reproducibility of Bruch's membrane opening-minimum rim width (BMO-MRW) measurements obtained with Spectralis optical coherence tomography (OCT) in normal and glaucoma subjects. METHODS: In total, 123 eyes from 123 subjects (65 healthy, 58 glaucoma subjects) were included. BMO-MRW measurements were repeated three times during the same visit using Spectralis OCT. The BMO points and internal limiting membrane were identified with automated software and corrected manually when necessary...
September 19, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28926210/clinical-relevance-of-retinal-structure-in-children-with-laser-treated-retinopathy-of-prematurity-versus-controls-using-optical-coherence-tomography
#3
Florina Stoica, Adela Chirita-Emandi, Nicoleta Andreescu, Alina Stanciu, Cristian G Zimbru, Maria Puiu
PURPOSE: We aimed to assess the macular anatomy using spectral domain optical coherence tomography (SD-OCT), in children born preterm who had laser-treated retinopathy of prematurity (ROP), and to investigate the relationship between structural changes in macula and visual function. METHODS: Thirty-seven 3-8 years old children were included in the study in two groups: 20 children born preterm [(<34 weeks of gestation, birthweight (BW) <2000 g)] who had laser-treated ROP in the Neonatology Department, Municipal Clinical Emergency Hospital of Timisoara, Romania; and 17 controls (children born at term, without eye disease, matched for age and gender)...
September 19, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28904216/anterior-segment-optical-coherence-tomography-of-previously-operated-extraocular-muscles
#4
Matthew S Pihlblad, James D Reynolds
BACKGROUND AND PURPOSE: To assess the possibility of determining the insertion distance from the limbus of previously operated extraocular rectus muscles (EOM) with the Heidelberg Spectralis anterior segment optical coherence tomography (AS-OCT). PATIENT AND METHOD: Subjects with a history of previous strabismus surgery underwent AS-OCT of the EOM before planned additional strabismus surgery. The EOM insertion distances from the limbus were measured pre-operatively on the AS-OCT and compared to the caliper distance measured during the strabismus surgery...
January 2017: American Orthoptic Journal
https://www.readbyqxmd.com/read/28902095/detection-of-treatment-naive-choroidal-neovascularization-in-age-related-macular-degeneration-by-swept-source-optical-coherence-tomography-angiography
#5
Daniel Ahmed, Martin Stattin, Alexandra Graf, Julia Forster, Carl Glittenberg, Ilse Krebs, Siamak Ansari-Shahrezaei
PURPOSE: To compare the detection rate of choroidal neovascularization (CNV) in treatment-naive neovascular age-related macular degeneration by swept source optical coherence tomography angiography (SS-OCTA, Topcon's DRI Triton) working at 1,050 nm wavelength versus fluorescence angiography. METHODS: Cross-sectional analysis of 156 eyes (107 neovascular age-related macular degeneration and 49 dry AMD) in 98 patients, previously diagnosed by multimodal imaging using fluorescein (FA) and indocyanine green angiography (Heidelberg's Spectralis) in a tertiary retina center, evaluated by SS-OCTA 4...
September 4, 2017: Retina
https://www.readbyqxmd.com/read/28885667/variations-in-retinal-nerve-fiber-layer-measurements-on-optical-coherence-tomography-after-implantation-of-trifocal-intraocular-lens
#6
Javier García-Bella, José M Martínez de la Casa, Paula Talavero González, José I Fernández-Vigo Escribano, Laura Valcarce Rial, Julián García-Feijóo
PURPOSE: To establish the changes produced after implantation of a trifocal intraocular lens (IOL) on retinal nerve fiber layer measurements performed with Fourier-domain optical coherence tomography (OCT). METHODS: This prospective study included 100 eyes of 50 patients with bilateral cataract in surgical range, no other associated ocular involvement, refractive errors between +5 and -5 spherical diopters, and less than 1.5 D of corneal astigmatism. The eyes were operated by phacoemulsification with implantation of 2 different trifocal IOLs (FineVision and AT LISA tri 839MP) in randomized equal groups...
September 5, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28885450/automated-evaluation-of-choroidal-thickness-and-minimum-rim-width-thickness-in-nonarteritic-anterior-ischemic-optic-neuropathy
#7
Ane Pérez-Sarriegui, Francisco J Muñoz-Negrete, Susana Noval, Victoria De Juan, Gema Rebolleda
BACKGROUND: The aim of this study was to evaluate and compare peripapillary choroidal thickness (pCT) and macular choroidal thickness (CT), Bruch membrane opening-minimum rim width (BMO-MRW), retinal nerve fiber layer (RNFL) thickness, and optic disc area among nonarteritic anterior ischemic optic neuropathy (NAION) eyes, the contralateral unaffected eyes, and healthy control eyes. METHODS: Twenty-six patients diagnosed with NAION (29 affected and 21 unaffected eyes) and 29 healthy matched control individuals (29 eyes) were analyzed by swept-source optical coherence tomography...
September 6, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28862734/utility-of-bruch-membrane-opening-based-optic-nerve-head-parameters-in-myopic-subjects
#8
Marina Sastre-Ibañez, Jose M Martinez-de-la-Casa, Gema Rebolleda, Pilar Cifuentes-Canorea, Maria Nieves-Moreno, Laura Morales-Fernandez, Federico Saenz-Frances, Julian Garcia-Feijoo
PURPOSE: To evaluate whether the new rim analysis software with spectral-domain optical coherence tomography (SD-OCT) shows advantages over the retinal nerve fiber layer (RNFL) thickness in patients with moderate myopia. METHODS: In this prospective cross-sectional study, we studied 65 healthy subjects, 37 with spherical refractive errors in the range of -3 to -6 D (moderate, G1) and 28 with less than -3 D (low/non-myopic, G0). All patients were examined with Heidelberg Spectralis SD-OCT, including Glaucoma Premium Module Edition (GPME) software...
August 11, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28858153/attenuation-coefficients-from-sd-oct-data-structural-information-beyond-morphology-on-rnfl-integrity-in-glaucoma
#9
Gijs Thepass, Hans G Lemij, Koenraad A Vermeer
PURPOSE: To explore the attenuation coefficient (AC) of the retinal nerve fiber layer (RNFL) in spectral domain optical coherence tomography (OCT) images, in healthy eyes and eyes affected by glaucoma. To assess the relation between RNLF AC, disease severity, RNFL thickness, visual field sensitivity threshold, spatial location and age. PATIENTS AND METHODS: We analyzed peripapillary circle scans of a clinical OCT device (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany) in 102 glaucoma patients and 90 healthy controls...
August 28, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28857943/visibility-of-optic-nerve-head-structures-with-spectral-domain-and-swept-source-optical-coherence-tomography
#10
Mónica M Loureiro, Jayme R Vianna, Vishva M Danthurebandara, Glen P Sharpe, Donna M Hutchison, Marcelo T Nicolela, Balwantray C Chauhan
PURPOSE: To compare the visibility of deep optic nerve head (ONH) structures and the visible area of the anterior surface of the lamina cribrosa (ASLC) with spectral-domain optical coherence tomography (SD-OCT) and swept-source OCT (SS-OCT). MATERIALS AND METHODS: In total, 33 glaucoma patients were imaged with SD-OCT (Spectralis, 24 radial B-scans centered on the ONH) and SS-OCT (Atlantis, 12 radial and a horizontal and vertical raster scan pattern containing 5 lines each, centered on the ONH)...
September 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28834947/classification-and-quantitative-analysis-of-geographic-atrophy-junctional-zone-using-spectral-domain-optical-coherence-tomography
#11
Jinfeng Qu, Swetha Bindu Velaga, Amir H Hariri, Muneeswar Gupta Nittala, Srinivas Sadda
PURPOSE: The junctional zone at the border of areas of geographic atrophy (GA) in eyes with nonneovascular age-related macular degeneration is an important target region for future therapeutic strategies. The goal of this study was to perform a detailed classification and quantitative characterization of the junctional zone using spectral domain optical coherence tomography. METHODS: Spectral domain optical coherence tomography volume cube scans (Spectralis OCT, 1024 × 37, Automatic Real Time > 9) were obtained from 15 eyes of 11 patients with GA because of nonneovascular age-related macular degeneration...
August 22, 2017: Retina
https://www.readbyqxmd.com/read/28832738/multimodal-assessment-of-patients-with-chronic-central-serous-chorioretinopathy
#12
Karlos Ítalo Souza Viana, Pedro M Souza Leão, Letícia Fernandes, Rubens Siqueira, Jefferson Ribeiro, Rodrigo Jorge
PURPOSE: To examine differences between fluorescein angiography (FA) and indocyanine green angiography (ICG) findings in patients with chronic central serous chorioretinopathy (CSC), comparing these with optical coherence tomography (OCT) findings. METHODS: Ten consecutive patients with chronic CSC (19 eyes; 7 men; mean age, 50.7 ± 8.4 years) underwent multimodal evaluation that included FA, ICG, and OCT (Spectralis HRA-OCT, Heidelberg Engineering, Heidelberg, Germany)...
June 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28832670/peripapillary-retinal-splitting-visualized-on-oct-in-glaucoma-and-glaucoma-suspect-patients
#13
Dilraj S Grewal, Daniel J Merlau, Pushpanjali Giri, Marion R Munk, Amani A Fawzi, Lee M Jampol, Angelo P Tanna
PURPOSE: To identify the risk factors for development of peripapillary retinal splitting (schisis) in patients with glaucoma or suspicion of glaucoma. SETTING: Glaucoma Clinic, Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL. METHODS: In this institutional cross-sectional study, 495 patients (990 eyes) who had undergone spectral-domain optical coherence tomography (OCT Spectralis HRA-OCT, Heidelberg Engineering) optic nerve head (ONH) imaging and did not have identifiable optic nerve pits, pseudopits or coloboma were included...
2017: PloS One
https://www.readbyqxmd.com/read/28829313/a-novel-nanoparticle-mediated-selective-inner-retinal-photocoagulation-sirep-for-diseases-of-the-inner-retina
#14
Rupesh Singh, Srinivas Rajaraman, Madhusudhanan Balasubramanian
PURPOSE: A novel nanoparticle mediated methodology for laser photocoagulation of the inner retina to achieve tissue selective treatment is presented. METHODS: Transport of 527 nm, 577 nm, and 810 nm laser, heat deposition and eventual thermal damage in vitreous, retina, RPE, choroid and sclera were modelled using Bouguer-Beer-Lambert law of absorption and solved numerically using the finite volume method. Nanoparticles were designed using Mie theory of scattering...
August 18, 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/28814416/the-volume-of-peripapillary-vessels-within-the-retinal-nerve-fibre-layer-an-optical-coherence-tomography-angiography-study-of-normal-subjects
#15
Davide Allegrini, Giovanni Montesano, Paolo Fogagnolo, Alfredo Pece, Roberta Riva, Mario R Romano, Luca Rossetti
BACKGROUND/AIMS: To investigate the contribution of vascular volume calculated by optical coherence tomography angiography (OCTA) to the measurement of peripapillary retinal nerve fibre layer (RNFL) thickness. METHODS: We used OCTA scans to build volumetric maps of the RNFL angiograms by thresholding the decorrelation images and summing the number of white pixels along the z-axis at each location. We used these maps to calculate the contribution of the vascular tissue to the RNFL thickness...
August 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28796875/optical-coherence-tomography-analysis-based-prediction-of-humphrey-24-2-visual-field-thresholds-in-patients-with-glaucoma
#16
Zhihui Guo, Young H Kwon, Kyungmoo Lee, Kai Wang, Andreas Wahle, Wallace L M Alward, John H Fingert, Daniel I Bettis, Chris A Johnson, Mona K Garvin, Milan Sonka, Michael D Abràmoff
Purpose: A pilot study showed that prediction of individual Humphrey 24-2 visual field (HVF 24-2) sensitivity thresholds from optical coherence tomography (OCT) image analysis is possible. We evaluate performance of an improved approach as well as 3 other predictive algorithms on a new, fully independent set of glaucoma subjects. Methods: Subjects underwent HVF 24-2 and 9-field OCT (Heidelberg Spectralis) testing. Nerve fiber (NFL), and ganglion cell and inner plexiform (GCL+IPL) layers were cosegmented and partitioned into 52 sectors matching HVF 24-2 test locations...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28780883/early-detection-of-macular-and-peripapillary-changes-with-spectralis-optical-coherence-tomography-in-patients-with-prediabetes
#17
Muhammed Şahin, Alparslan Şahin, Faruk Kılınç, Ümit Karaalp, Harun Yüksel, Zeynep Gürsel Özkurt, Fatih Mehmet Türkcü, İhsan Çaça
PURPOSE: To compare the retina ganglion cell complex (GCC) layer and peripapillary nerve fibre layer thickness (pRNFL) in patients with prediabetes and healthy subjects analysed by spectral domain optical coherence tomography (SD-OCT). METHODS: This cross-sectional and comparative study included prediabetic patients and healthy subjects. All participants underwent SD-OCT measurement of pRNFL thickness, and GCC thickness. RESULTS: A total of 30 eyes of the 30 patients with prediabetes and 30 eyes of 30 controls were included...
August 5, 2017: Archives of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28780617/the-association-of-helicobacter-pylori-with-choroidal-and-retinal-nerve-fiber-layer-thickness
#18
Mehmet Erol Can, Fatma Efe Kaplan, Mehmet Murat Uzel, Hasan Kiziltoprak, Mustafa Cagri Ergun, Mustafa Koc, Gülcin Simsek
PURPOSE: To investigate the effect of Helicobacter pylori (H. pylori) infection on choroidal thickness (CT) and retinal nerve fiber layer thickness (RNFLT). METHODS: The study included 25 patients with H. pylori infection and 25 healthy individuals as the control group. Helicobacter pylori patients were classified as the pre-treatment (Group 1; n: 25) and the post-treatment (Group 2; n: 25). RNFLT and CT were measured before and after treatment of H. pylori infection, using enhanced depth imaging (EDI) spectral-domain optical coherence tomography (Spectralis, Heidelberg Engineering, Heidelberg, Germany)...
August 5, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28774935/comparing-optical-coherence-tomography-radial-and-cube-scan-patterns-for-measuring-bruch-s-membrane-opening-minimum-rim-width-bmo-mrw-in-glaucoma-and-healthy-eyes-cross-sectional-and-longitudinal-analysis
#19
Sami W Kabbara, Linda M Zangwill, Rusdeep Mundae, Naama Hammel, Christopher Bowd, Felipe A Medeiros, Robert N Weinreb, Akram Belghith
AIM: To compare the cube and radial scan patterns of the spectral domain optical coherence tomography (SD-OCT) for quantifying the Bruch's membrane opening minimum rim width (BMO-MRW). METHODS: Sixty healthy eyes and 189 glaucomatous eyes were included. The optic nerve head cube and radial pattern scans were acquired using Spectralis SD-OCT. BMO-MRWs were automatically delineated using the San Diego Automated Layer Segmentation Algorithm. The BMO-MRW diagnostic accuracy for glaucoma detection and rates of change derived from the two scan patterns were compared...
August 3, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28771565/segmented-inner-plexiform-layer-thickness-as-a-potential-biomarker-to-evaluate-open-angle-glaucoma-dendritic-degeneration-of-retinal-ganglion-cell
#20
Eun Kyoung Kim, Hae-Young Lopilly Park, Chan Kee Park
PURPOSE: To evaluate the changes of retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), and ganglion cell-inner plexiform layer (GCIPL) thicknesses and compare structure-function relationships of 4 retinal layers using spectral-domain optical coherence tomography (SD-OCT) in macular region of glaucoma patients. METHODS: In cross-sectional study, a total of 85 eyes with pre-perimetric to advanced glaucoma and 26 normal controls were enrolled...
2017: PloS One
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