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https://www.readbyqxmd.com/read/28632403/effect-of-amblyopia-treatment-on-choroidal-thickness-in-children-with-hyperopic-anisometropic-amblyopia
#1
Seray Aslan Bayhan, Hasan Ali Bayhan
PURPOSE: To evaluate choroidal thickness (CT) in the eyes of children with hyperopic anisometropic amblyopia and to assess changes in CT during amblyopia treatment using spectral-domain optical coherence tomography (SD-OCT). METHODS: This longitudinal study, initially enrolled 40 patients, aged 3-9 years with hyperopic anisometropic amblyopia. Patients underwent treatment with refractive correction alone for 16 weeks and if needed, with refractive correction and patching treatment thereafter (6 months)...
June 20, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28630788/evaluation-of-ganglion-cell-inner-plexiform-layer-thickness-after-vitreoretinal-surgery-with-internal-limiting-membrane-peeling-in-cases-with-idiopathic-macular-hole
#2
Sibel Demirel, Ahmed Abdullayev, Özge Yanık, Figen Batıoğlu, Emin Özmert
OBJECTIVES: To evaluate macular retinal ganglion cell-inner plexiform layer (GCIPL) thickness after vitrectomy with internal limiting membrane (ILM) peeling for idiopathic macular holes using spectral domain optical coherence tomography (SD-OCT). MATERIALS AND METHODS: Eighteen eyes of 18 patients with unilateral idiopathic macular hole who underwent vitrectomy with ILM peeling were retrospectively analyzed. Healthy fellow eyes of the patients and 18 eyes of 18 age-matched healthy individuals constituted the control group...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28629391/anterior-lens-capsule-and-epithelium-thickness-measurements-using-spectral-domain-optical-coherence-tomography
#3
Jing Dong, Yading Jia, Yaqin Zhang, Haining Zhang, Zhijie Jia, Suhua Zhang, Qiang Wu, Qingmao Hu, Tianqiao Zhang, Xiaogang Wang
BACKGROUND: To investigate the anterior lens capsule and epithelium thickness (defined as anterior lens capsular complex: ALCC) in normal Chinese subjects using spectral-domian optical coherence tomography (SD-OCT) and examine the factors that may influence the ALCC, such as age, gender, pupil diameter (PD) and signal strength index (SSI). METHODS: A prospective observational case series. One-hundred-thirty-four normal subjects (134 eyes) were included. The ALCCs were determined manually via SD-OCT...
June 19, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28628662/quantitative-analysis-of-retinal-layers-on-three-dimensional-spectral-domain-optical-coherence-tomography-for-pituitary-adenoma
#4
Min Sun, Zhiqiang Zhang, Chiyuan Ma, Suihua Chen, Xinjian Chen
PURPOSE: To quantitatively investigate the characteristics of eyes with pituitary adenoma presented by three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) using three common indices, including thickness, optical intensity ratio, and optical intensity attenuation coefficient (OIAC). METHODS: The SD-OCT database of 38 patients with pituitary adenoma and 39 normal controls were included in the study. Quadrantal and average measurements of thickness, optical intensity ratio, and OIAC were calculated for macular retinal nerve fiber layer (mRNFL), ganglion cell layer (GCL) combined with inner plexiform layer (IPL) (GCIPL) and/or the collective ganglion cell complex (GCC)...
2017: PloS One
https://www.readbyqxmd.com/read/28624323/post-receptor-neuronal-loss-in-intermediate-age-related-macular-degeneration
#5
Enrico Borrelli, Nizar Saleh Abdelfattah, Akihito Uji, Muneeswar Gupta Nittala, David S Boyer, SriniVas R Sadda
PURPOSE: To investigate the relationship between ganglion cell complex (GCC) thickness and photoreceptor alterations in eyes with intermediate age-related macular degeneration (AMD). DESIGN: Retrospective case-control study. METHODS: We collected data from 68 eyes with intermediate AMD from 68 patients with spectral domain optical coherence tomography (SD-OCT) imaging. A control group of 50 eyes from 50 healthy subjects was included for comparison...
June 14, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28622397/looking-for-the-most-suitable-orthotopic-retinoblastoma-mouse-model-in-order-to-characterize-the-tumoral-development
#6
Stéphanie Lemaitre, Florent Poyer, Sergio Marco, Paul Fréneaux, François Doz, Isabelle Aerts, Laurence Desjardins, Nathalie Cassoux, Carole D Thomas
Purpose: Because retinoblastoma therapies have many adverse effects, new approaches must be developed and evaluated on animal models. We describe orthotopic xenograft models of retinoblastoma using different strains of mice, suitable for this purpose. Methods: Human retinoblastoma tumors were established on immunodeficient mice by subcutaneous engraftment of tumors from enucleated eyes. The orthotopic model was obtained by subretinal injections of suspension cells into the right eye of immunodeficient (Swiss-nude, severe combined immunodeficiency [SCID]) and immunocompetent mice (C57BL/6N, B6Albino)...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28622313/optical-coherence-tomography-analysis-of-evolution-of-bruch-s-membrane-features-in-angioid-streaks
#7
A Marchese, M Parravano, A Rabiolo, A Carnevali, E Corbelli, M V Cicinelli, M Battaglia Parodi, L Querques, F Bandello, G Querques
PurposeTo describe optical coherence tomography (OCT) features in the Bruch's membrane (BM) of eyes with angioid streaks (AS) and evaluate their evolution over the follow-up.Patients and methodsPatients with AS presenting between March 2016 and September 2016 at two tertiary referral centers were consecutively recruited in this study. Eligibility criteria included prior spectral domain (SD)-OCT images, taken at least 3 months before at the same referral center, with automated eye tracking and image alignment modules...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28619430/effect-of-fingolimod-fty720-on-choroidal-thickness-in-patients-with-multiple-sclerosis
#8
Ali Kal, Mahmut Oğuz Ulusoy, Bahriye Horasanlı, Şefik Cezairlioğlu, Öznur Kal
OBJECTIVE: Using spectral domain optical coherence tomography (SD-OCT), to compare the choroidal thickness in a healthy population (group 1), with newly diagnosed multiple sclerosis (MS) patients (group 2), with MS patients who underwent β-interferon monotherapy (group 3) and MS patients who underwent fingolimod therapy for 1 year (group 4) METHODS: Twenty-five control subjects (25 eyes), 24 newly diagnosed (24 eyes) MS patients, 22 MS patients who underwent fingolimod monotherapy for 1 year (22 eyes), and 24 MS patients who underwent β-interferon monotherapy for 1 year (24 eyes) were included in this study...
May 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28616715/effects-of-intravitreal-injection-of-bevacizumab-with-or-without-anterior-chamber-paracentesis-on-intraocular-pressure-and-peripapillary-retinal-nerve-fiber-layer-thickness-a-prospective-study
#9
Masoud Soheilian, Saeed Karimi, Talieh Montahae, Homayoun Nikkhah, Seyed Aliasghar Mosavi
PURPOSE: To investigate the effects of intravitreal injection of bevacizumab (IVB) with or without anterior chamber paracentesis on intraocular pressure (IOP) and peripapillary retinal nerve fiber layer (PRNFL) thickness. METHODS: In this prospective randomized clinical trial, 90 eyes with center involving diabetic macular edema or wet type age-related macular degeneration (AMD) were randomly assigned to receive IVB either without (group A) or with (group B) anterior chamber paracentesis...
June 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28615925/anterior-lamina-cribrosa-surface-depth-in-healthy-saudi-females
#10
Amira El-Agamy, Fayrouz Oteaf, Mohamed Berika
PURPOSE: This study was conducted to determine normative profile of anterior lamina cribrosa surface depth (ALCSD) in healthy Saudi females using Topcon Three-Dimensional (3D) Optical Coherence Tomography (OCT) 2000 - Spectral Domain (SD-OCT). In addition, the correlation between ALCSD and other clinical factors such as age, refractive error, intraocular pressure (IOP), central corneal thickness, anterior chamber depth, axial length, retinal nerve fiber layer thickness, and disk area was also assessed...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28613353/retinal-ganglion-cell-loss-in-children-with-type-1-diabetes-mellitus-without-diabetic-retinopathy
#11
Omer Karti, Ozlem Nalbantoglu, Saygin Abali, Ziya Ayhan, Selma Tunc, Tuncay Kusbeci, Behzat Ozkan
BACKGROUND AND OBJECTIVE: Early diabetic retinal changes in children with type 1 diabetes mellitus (T1DM) without diabetic retinopathy (DR) were examined using spectral-domain optical coherence tomography (SD-OCT). PATIENTS AND METHODS: Sixty children with T1DM without DR and 60 normal children were enrolled in the study. SD-OCT was used to measure the ganglion cell-inner plexiform layer (GC-IPL) and retinal nerve fiber (RNFL) thicknesses in all participants. RESULTS: The GC-IPL thickness was significantly decreased in all quadrants except the superior-nasal quadrant in children with diabetes (P < ...
June 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28613221/clinicopathologic-correlation-of-retinal-angiomatous-proliferation-treated-with-ranibizumab
#12
Alison H Skalet, Audra K Miller, Michael L Klein, Andreas K Lauer, David J Wilson
PURPOSE: To describe histopathologic features of an eye with retinal angiomatous proliferation (RAP) secondary to age-related macular degeneration treated with serial ranibizumab injections and to correlate these findings with spectral domain optical coherence tomography. METHODS: Histopathologic features from serial sections through the globe of a 93-year-old man with age-related macular degeneration were studied and compared with spectral domain optical coherence tomography images obtained 7 weeks before his death...
April 26, 2017: Retina
https://www.readbyqxmd.com/read/28607770/detailed-distribution-of-corneal-epithelial-thickness-and-correlated-characteristics-measured-with-sd-oct-in-myopic-eyes
#13
Yanan Wu, Yan Wang
PURPOSE: To investigate the detailed distribution of corneal epithelial thickness in single sectors and its correlated characteristics in myopic eyes. METHODS: SD-OCT was used to measure the corneal epithelial thickness distribution profile. Differences of corneal epithelial thickness between different parameters and some correlations of characteristics were calculated. RESULTS: The thickest and thinnest part of epithelium were found at the nasal-inferior sector (P < 0...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28607414/diagnostic-capability-of-pulsar-perimetry-in-pre-perimetric-and-early-glaucoma
#14
Kazunori Hirasawa, Natsumi Takahashi, Kazuhiro Matsumura, Masayuki Kasahara, Nobuyuki Shoji
This study aimed to compare the diagnostic capability of Pulsar perimetry (Pulsar) in pre-perimetric glaucoma (PPG) and early glaucoma (EG) with that of Flicker perimetry (Flicker) and spectral-domain optical conference tomography (SD-OCT). This prospective cross-sectional study included 25 eyes of 25 PPG patients, 35 eyes of 35 EG patients, and 42 eyes of 42 healthy participants. The diagnostic capability using the area under the curve (AUC) of the best parameter and agreement of detectability between structural and functional measurements were compared...
June 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28606265/-the-fundus-manifestations-and-sd-oct-findings-of-patients-with-acute-vogt-koyanagi-harada-disease
#15
B Li, J J Ye, M F Zhang, D H Li
Objective: To conclude the characteristics of fundus appearance and spectral domain optical coherence tomography(SD-OCT) findings of patients with acute Vogt-Koyanagi-Harada (VKH) disease. Methods: The clinical data of 17 patients (34 eyes) diagnosed of acute VKH in Peking Union Medical College Hospital from Jan. 2012 to Dec. 2014 were studied retrospectively.Examinations included visual acuity, slit lamp, fundus, color fundus pictures, FFA and SD-OCT. Results: Eight men and 9 women were enrolled with mean age of (40...
June 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28602014/correlation-between-morphological-changes-and-functional-outcomes-of-recent-onset-macula-off-rhegmatogenous-retinal-detachment-prognostic-factors-in-rhegmatogenous-retinal-detachment
#16
Murat Karacorlu, Isil Sayman Muslubas, Mumin Hocaoglu, Serra Arf, Mehmet Giray Ersoz
PURPOSE: To assess correlation between preoperative and postoperative findings and surgical factors, and postoperative functional outcomes after successful repair of acute macula-off rhegmatogenous retinal detachment (RRD). METHODS: Forty-four eyes of 44 patients with recent-onset macula-off RRD who had primary pars plana vitrectomy were included in this retrospective study. Best-corrected visual acuity (BCVA) and retinal and choroidal changes on spectral-domain optical coherence tomography (SD-OCT) were evaluated before and after surgery...
June 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28601911/repeatability-of-ganglion-cell-inner-plexiform-layer-thickness-measurements-using-spectral-domain-oct-in-branch-retinal-vein-occlusion
#17
Yeon Hee Lee, Min-Su Kim, Seung Il Ahn, Hye Jin Park, Kyung Sup Shin, Jung-Yeul Kim
PURPOSE: To analyze the repeatability of thickness measurements of the central macula, ganglion cell-inner plexiform layer (GC-IPL), and retinal nerve fiber layer (RNFL) using spectral-domain optical coherence tomography (SD-OCT) before and after treatment of macular edema in branch retinal vein occlusion (BRVO). METHODS: We analyzed patients with BRVO who visited our retinal clinic. The repeatability of the thickness measurements were compared using the intraclass correlation coefficient (ICC) and coefficient of variation (COV) of affected versus normal fellow eyes...
June 11, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28601586/evaluating-structural-progression-of-retinitis-pigmentosa-after-cataract-surgery
#18
Joaquin O De Rojas, Kaspar Schuerch, Priya M Mathews, Thiago Cabral, Albert Hazan, Janet Sparrow, Stephen H Tsang, Leejee H Suh
PURPOSE: To determine whether cataract surgery accelerates disease progression in retinitis pigmentosa (RP). DESIGN: Retrospective cohort study. METHODS: Seventy eyes of 40 patients with RP were categorized as having had phacoemulsification with intraocular lens implantation versus no cataract surgery at a single tertiary-level institution. Spectral domain optical coherence tomography (SD-OCT) was used to measure the ellipsoid zone (EZ) width, which has been demonstrated to be a reliable marker of RP severity, at baseline and throughout follow-up (median 768 days)...
June 7, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28599336/-intraoperative-optical-coherence-tomography-in-vitreoretinal-surgery-clinical-experiences-and-future-developments
#19
Mathias M Maier, Ali Nasseri, Carsten Framme, Sabrina Bohnacker, Matthias D Becker, Dominik Heinrich, Hansjürgen Agostini, Nikolaus Feucht, Chris P Lohmann, Lars Olof Hattenbach
Purpose High resolution optical coherence tomography (OCT) enables better visualization of ophthalmic microstructures than conventional imaging. When using an ophthalmic microscope, integrated optical coherence tomography (iOCT) high resolution real time visualization is possible. Methods We report on the first 110 patients operated on using a microscope integrated OCT (iOCT) during surgical procedures for the treatment of various posterior segment pathologies. Results Microstructural changes that appeared during surgery were depicted precisely by iOCT, and the morphology visualized before and after each surgical step was used to help deciding how to adapt the surgical flow...
June 9, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28599332/-efficacy-and-safety-profile-of-ocriplasmin-treatment-an-update
#20
Denise Compera, Siegfried Priglinger, Ricarda Gisela Schumann
Pharmacological vitreolysis with ocriplasmin is an effective treatment option for eyes with vitreomacular traction. Pre-marketing and post-marketing clinical studies revealed an improvement of visual function in ocriplasmin treated eyes and showed a release of traction in up to 78% of cases. Treatment success is related to patient selection based on positive predictive factors. Adverse events, such as visual acuity loss, dyschromatopsia or photopsia are known to be self-limited in the majority of eyes. Structural outer retinal layer changes, such as ellipsoid zone disturbances or subretinal fluid accumulation on SD-OCT analysis, as well as ERG abnormalities, are transient and correlated to VMT release...
June 9, 2017: Klinische Monatsblätter Für Augenheilkunde
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