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https://www.readbyqxmd.com/read/29338130/correlation-between-morphological-characteristics-in-spectral-domain-optical-coherence-tomography-different-functional-tests-and-a-patient-s-subjective-handicap-in-acute-central-serous-chorioretinopathy
#1
Bianca S Gerendas, Julia-Sophie Kroisamer, Wolf Buehl, Sandra M Rezar-Dreindl, Katharina M Eibenberger, Eleonore Pablik, Ursula Schmidt-Erfurth, Stefan Sacu
PURPOSE: The purpose of this study was to identify quantitatively measurable morphologic optical coherence tomography (OCT) characteristics in patients with an acute episode of central serous chorioretinopathy (CSC) and evaluate their correlation to functional and psychological variables for their use in daily clinical practice. METHODS: Retinal thickness (RT), the height, area and volume of subretinal fluid (SRF)/pigment epithelium detachments were evaluated using the standardized procedures of the Vienna Reading Center...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29332119/autofluorescence-of-skin-advanced-glycation-end-products-as-a-risk-factor-for-open-angle-glaucoma-the-alienor-study
#2
Cedric Schweitzer, Audrey Cougnard-Gregoire, Vincent Rigalleau, Jean-Francois Dartigues, Florence Malet, Marie-Benedicte Rougier, Marie-Noelle Delyfer, Catherine Helmer, Jean-Francois Korobelnik, Cecile Delcourt
Purpose: To analyze the association between skin autofluorescence (sAF), estimating tissue accumulation of advanced glycation end-products (AGEs), and open angle glaucoma (OAG) in an elderly population. Methods: The Antioxydants, Lipides Essentiels, Nutrition and maladies OculaiRes (ALIENOR) study is an on-going epidemiologic population-based study on age-related eye diseases. In 2009 to 2010, 624 subjects, aged 74 years or older, were recruited. All subjects underwent a complete eye examination, including optic disc color photography and spectral-domain optical coherence tomography (SD-OCT) examination...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29327033/disorganization-of-inner-retina-and-outer-retinal-morphology-in-diabetic-macular-edema
#3
Radha Das, Gareth Spence, Ruth E Hogg, Michael Stevenson, Usha Chakravarthy
Importance: In diabetic macular edema (DME), identification of baseline markers on spectral-domain optical coherence tomography (SD-OCT) and their association with severity of diabetic retinopathy (DR) might aid in disease management and the design of future trials. Objective: To examine associations between DR severity, retinal morphology on SD-OCT, and visual acuity in participants with DME. Design, Setting, and Participants: This cross-sectional observational case series was conducted at a single tertiary care referral center...
January 11, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29326849/spectral-domain-optical-coherence-tomography-findings-in-carotid-artery-disease
#4
Akın Çakır, Eyüp Düzgün, Serkan Demir, Yavuz Çakır, Melih Hamdi Ünal
Objectives: To evaluate the effect of carotid artery disease on retinal morphology by means of spectral domain optical coherence tomography (SD-OCT). Materials and Methods: We examined 23 eyes with internal carotid artery (ICA) stenosis and 24 age- and gender-matched healthy eyes as a control group in this prospective, case-control study. Compherensive ophthalmic examination and SD-OCT scan were performed to all the patients. The average RNFL and macular thicknesses (MT) in the nine macular ETDRS areas were the major OCT measurements for our study...
December 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29324931/vitrectomy-with-fibrovascular-membrane-delamination-for-proliferative-diabetic-retinopathy-with-or-without-preoperative-avastin
#5
M Vasalaki, E Papavasileiou, C Garnavou-Xirou, S Velissaris, V Zygoura, D McHugh, T L Jackson
OBJECTIVE: To describe and compare 1. The changes in intraretinal microstructure using serial spectral domain optical coherence tomography (SD-OCT) preceding and following pars plana vitrectomy and delamination of fibrovascular membranes and 2. Intraoperative and postoperative complications in patients with proliferative diabetic retinopathy (PDR) who had preoperative Avastin (group A) or not (group B). SUBJECTS AND METHOD: This retrospective, interventional case series includes 113 eyes...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29318448/elevated-serum-igf-1-level-enhances-retinal-and-choroidal-thickness-in-untreated-acromegaly-patients
#6
Xia Zhang, Jin Ma, Yuhan Wang, Lüe Li, Lu Gao, Xiaopeng Guo, Bing Xing, Yong Zhong
PURPOSE: 1) To compare the retinal, choroidal, Haller's layer, and Sattler's/choriocapillaris thicknesses of untreated acromegaly patients without chiasm compression or diabetes mellitus and healthy controls. 2) To evaluate the correlations of retinal and choroidal thicknesses with serum growth hormone (GH) and insulin-like growth factor 1 (IGF) burden. METHODS: This prospective, case-control study included 27 untreated acromegaly patients and 27 sex-matched and age-matched controls...
January 10, 2018: Endocrine
https://www.readbyqxmd.com/read/29315706/a-basis-for-customising-perimetric-locations-within-the-macula-in-glaucoma
#7
Muhammed S Alluwimi, William H Swanson, Victor E Malinovsky, Brett J King
PURPOSE: It has been recognised that the 24-2 grid used for perimetry may poorly sample the macula, which has been recently identified as a critical region for diagnosing and managing patients with glaucoma. We compared data derived from patients and controls to investigate the efficacy of a basis for customising perimetric locations within the macula, guided by en face images of retinal nerve fibre layer (RNFL) bundles. METHODS: We used SD-OCT en face montages (www...
January 8, 2018: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29313132/-rpe-morphometry-in-geographic-atrophy-due-to-amd
#8
A Wagner, A Mohi, M Ranjbar, S Grisanti, M Rudolf
BACKGROUND: The geographic atrophy (GA) junctional zone includes changes in retinal pigment epithelium (RPE) and Bruch's membrane complex that are still difficult to interpret even with clinical high-resolution imaging technologies. We measured and evaluated degenerative RPE cell changes in histological sections of GA eyes. METHODS: In this study seven GA eyes were evaluated by light microscopy. In three eye sections, zones of typical RPE alterations were graded (0 = normal; 1 = irregular cells but intact layer; 2 = rounded, enlarged, and/or heaped cells; 3 = migrating cells in retina; 4 = RPE absent)...
January 8, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29306951/longitudinal-analysis-of-drusen-volume-in-intermediate-age-related-macular-degeneration-using-two-spectral-domain-optical-coherence-tomography-scan-patterns
#9
Sarah Thiele, Jennifer Nadal, Monika Fleckenstein, Petra P Fang, Maximilian Pfau, Matthias Schmid, Rui Hua, Frank G Holz, Steffen Schmitz-Valckenberg
PURPOSE: To evaluate two different spectral-domain optical coherence tomography (SD-OCT) scan patterns in eyes with intermediate age-related macular degeneration (AMD) for the longitudinal assessment of drusen volume. METHODS: The data of 38 eyes of 38 AMD patients (age 69.97 ± 6.08 years) were included. The longitudinal drusen volume over 4 years was analyzed by annual SD-OCT raster scanning (field size 20 × 15°). Two raster scan patterns (A/B) differed in the distance between neighboring B-scans (240 vs...
January 5, 2018: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/29306864/characteristic-optical-coherence-tomography-findings-in-patients-with-primary-vitreoretinal-lymphoma-a-novel-aid-to-early-diagnosis
#10
Robert J Barry, Anastasia Tasiopoulou, Philip I Murray, Praveen J Patel, Mandeep S Sagoo, Alastair K Denniston, Pearse A Keane
BACKGROUND: The diagnosis of primary vitreoretinal lymphoma (PVRL) poses significant difficulties; presenting features are non-specific and confirmation usually necessitates invasive vitreoretinal biopsy. Diagnosis is often delayed, resulting in increased morbidity and mortality. Non-invasive imaging modalities such as spectral domain optical coherence tomography (SD-OCT) offer simple and rapid aids to diagnosis. We present characteristic SD-OCT images of patients with biopsy-positive PVRL and propose a number of typical features, which we believe are useful in identifying these lesions at an early stage...
January 6, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29305731/association-of-bruch-s-membrane-opening-and-optic-disc-morphology-to-axial-length-and-visual-field-defects-in-eyes-with-primary-open-angle-glaucoma
#11
Hideo Nakanishi, Kenji Suda, Munemitsu Yoshikawa, Tadamichi Akagi, Takanori Kameda, Hanako Ohashi Ikeda, Satoshi Yokota, Yasuo Kurimoto, Akitaka Tsujikawa
PURPOSE: To examine the morphology of Bruch's membrane opening (BMO), optic disc, and peripapillary atrophy (PPA) by scanning laser ophthalmoscopy (SLO) and spectral-domain optical coherence tomography (SD-OCT), and to determine their association with the axial length and visual field defects. METHODS: This was a cross-sectional study of 94 eyes of 56 subjects; 77 eyes were diagnosed with primary open-angle glaucoma and 17 eyes as normal. The margins of the optic disc were determined in the SLO images, and that of the BMO in the SD-OCT images...
January 5, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29304270/a-new-oct-finding-in-purtscher-like-retinopathy
#12
Sevil Ari Yaylali, Nedim Bromand, Guler Kilic
The authors report a new spectral-domain optical coherence tomography (SD-OCT) appearance observed in two patients with Purtscher-like retinopathy. In this prospective case series of three eyes of two patients with Purtscher-like retinopathy, the patients were assessed with biomicroscopy, fluorescein angiography (FA), and SD-OCT. The last examinations of the patients were performed at 3 months and 12 months, respectively. Both patients presented with decreased visual acuity. Fundus examination revealed a whitish-appearing parafoveal retina and scattered cotton-wool spots in the posterior retina...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29304261/an-evaluation-of-the-relationship-between-clinically-unilateral-pseudoexfoliation-syndrome-and-age-related-macular-degeneration
#13
Mehmet Ozgur Zengin, Omer Karti, Eyyup Karahan, Tuncay Kusbeci
BACKGROUND AND OBJECTIVE: To evaluate the relationship between age-related macular degeneration (AMD) and clinically unilateral pseudoexfoliation syndrome (XFS). PATIENTS AND METHODS: Seventy-six patients (152 eyes) with bilateral AMD and clinically unilateral XFS were included. Eyes with AMD were divided into three stages (early, intermediate, and late), based on the Beckman Initiative for Macular Research Classification Committee of fundus findings. The distribution of AMD lesions was assessed in both groups, and the subfoveal choroidal thickness (SFCT) was measured using enhanced depth imaging spectral-domain optical coherence tomography (SD-OCT)...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29303148/visual-outcomes-and-anatomic-changes-after-sub-threshold-micropulse-yellow-laser-577-nm-treatment-for-chronic-central-serous-chorioretinopathy-long-term-follow-up
#14
A Arsan, H S Kanar, A Sonmez
PurposeTo analyze the long-term efficacy of 577 nm sub-threshold micropulse yellow laser (SMYL) in the treatment of chronic central serous chorioretinopathy (CCSC) and to evaluate the anatomic outcome, visual results and safety profile of the treatment.Patients and methodsThis prospective study assessed 39 eyes of 39 patients with non-resolving CCSC lasting more than three months. All eyes were treated by using 577 nm SMYL system with 5% duty cycle (DC) and each patients was monitored monthly. The main outcome measures were best-corrected visual acuity (BCVA), contrast sensitivity (CS) and subretinal fluid (SRF) height, central macular thickness (CMT), central macular volume (CMV), total macular volume (TMV), and subfoveal choroidal thickness (SFCT) measured by spectral domain optical coherence tomography (SD-OCT)...
January 5, 2018: Eye
https://www.readbyqxmd.com/read/29302382/beyond-retinal-layers-a-deep-voting-model-for-automated-geographic-atrophy-segmentation-in-sd-oct-images
#15
Zexuan Ji, Qiang Chen, Sijie Niu, Theodore Leng, Daniel L Rubin
Purpose: To automatically and accurately segment geographic atrophy (GA) in spectral-domain optical coherence tomography (SD-OCT) images by constructing a voting system with deep neural networks without the use of retinal layer segmentation. Methods: An automatic GA segmentation method for SD-OCT images based on the deep network was constructed. The structure of the deep network was composed of five layers, including one input layer, three hidden layers, and one output layer...
January 2018: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29299741/functional-and-structural-outcomes-of-ilm-peeling-in-uncomplicated-macula-off-rrd-using-microperimetry-en-face-oct
#16
Mohamed Gaber Ahmed Mohamed Eissa, Mohamad Amr Salah Eddin Abdelhakim, Tamer Ahmed Macky, Mohamed Mahmoud Khafagy, Hassan Aly Mortada
PURPOSE: To investigate functional and structural outcomes of internal limiting membrane (ILM) peeling during primary vitrectomy for uncomplicated macula-off rhegmatogenous retinal detachment (RRD). METHODS: In this prospective interventional randomized comparative study, 43 eyes (43 patients) were randomly divided into group A (20), and group B (23), with and without ILM peeling respectively. Patients were evaluated clinically, and by spectral-domain optical coherence tomography (SD-OCT) and microperimetry (MP) following silicone oil removal...
January 3, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29290187/peripapillary-retinal-nerve-fiber-layer-rnfl-thickness-measurements-by-topcon-sd-oct-in-myopic-patients
#17
Nadia Akhtar, Ayisha Kausar, Farooq Afzal, Syed Khalid Ali, Nida Hamid
OBJECTIVE: To evaluate the effect of low-to-moderate myopia on peripapillary retinal nerve fiber layer (RNFL) thickness measured by Topcon SD optical coherence tomography (OCT). STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: Ophthalmology Department, Shifa Foundation Falahee Clinic, over a period of one year starting from June 2015. METHODOLOGY: A total of 43 eyes of 43 patients, having mild to moderate myopic refractive error, were enrolled in the study...
January 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29282403/epiretinal-membrane-in-dome-shaped-macula-complicated-with-serous-retinal-detachment-transient-efficacy-of-surgery
#18
Guillaume Soudier, Alain Gaudric, Vincent Gualino, Mathieu Nardin, Claude Speeg-Schatz, David Gaucher
Dome-shaped macula (DSM) is an entity recently described as a convex anterior protrusion of the macular area within a posterior myopic staphyloma. Specific complications were associated with DSM, like serous retinal detachment (SRD). We describe a woman presenting with a decreased vision at 20/50. SD-OCT scans were performed, showing a macular bulge. SRD was present and an epiretinal membrane could also be observed. Fluorescein angiography and indocyanin green angiography did not show any leakage nor choroidal neovascularization...
September 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29275341/qualitative-and-quantitative-assessment-of-posterior-segment-optical-coherence-tomography-images-using-standard-photos-the-liwan-eye-study
#19
Sean K Wang, Xinxing Guo, Ou Xiao, Yanxian Chen, Ran Liu, Wenyong Huang, Mingguang He
BACKGROUND/AIMS: To develop a standardised grading scheme, using standard photos, for spectral-domain ocular coherence tomography (SD-OCT) images of the posterior eye and evaluate the interobserver agreement among trained ophthalmologists in identifying pathological changes. METHODS: Subjects were recruited from Liwan District, Guangzhou, with SD-OCT data collection from June 2013 to November 2013 as part of 10-year follow-up visits from the Liwan Eye Study. All subjects underwent SD-OCT imaging of the macula with scanning lines analysed by two ophthalmologists to assess for the presence of 12 different posterior segment lesions...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29259908/optic-nerve-compression-the-role-of-the-lamina-cribrosa-and-translaminar-pressure
#20
Mario R Romano, Gilda Cennamo, Maria Angelica Breve, Michela Piedepalumbo, Claudio Iovino, Nunzio Velotti, Giovanni Cennamo
AIM: To describe the morphological changes of the lamina cribrosa (LC) in patients with optic nerve compression. METHODS: Cross-sectional study. Twenty eyes with optic nerve compression, affected by Graves' ophthalmopathy (GO) were compared with 18 refractive error-matched healthy eyes. The following examinations were performed: best-corrected visual acuity (BCVA), intraocular pressure, optic nerve echography, visual field, SD-OCT including the retinal nerve fiber layer (RNFL), ganglion cell complex (GCC), and LC thickness and extent...
2017: International Journal of Ophthalmology
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