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oximetry and altitude and body mass index

Luu V Pham, Christopher Meinzen, Rafael S Arias, Noah G Schwartz, Adi Rattner, Catherine H Miele, Philip L Smith, Hartmut Schneider, J Jaime Miranda, Robert H Gilman, Vsevolod Y Polotsky, William Checkley, Alan R Schwartz
Pham, Luu V., Christopher Meinzen, Rafael S. Arias, Noah G. Schwartz, Adi Rattner, Catherine H. Miele, Philip L. Smith, Hartmut Schneider, J. Jaime Miranda, Robert H. Gilman, Vsevolod Y. Polotsky, William Checkley, and Alan R. Schwartz. Cross-sectional comparison of sleep-disordered breathing in native Peruvian highlanders and lowlanders. High Alt Med Biol. 18:11-19, 2017. BACKGROUND: Altitude can accentuate sleep disordered breathing (SDB), which has been linked to cardiovascular and metabolic diseases...
March 2017: High Altitude Medicine & Biology
Catherine H Miele, Alan R Schwartz, Robert H Gilman, Luu Pham, Robert A Wise, Victor G Davila-Roman, Jonathan C Jun, Vsevolod Y Polotsky, J Jaime Miranda, Fabiola Leon-Velarde, William Checkley
Miele, Catherine H., Alan R. Schwartz, Robert H. Gilman, Luu Pham, Robert A. Wise, Victor G. Davila-Roman, Jonathan C. Jun, Vsevolod Y. Polotsky, J. Jaime Miranda, Fabiola Leon-Velarde, and William Checkley. Increased cardiometabolic risk and worsening hypoxemia at high altitude. High Alt Med Biol. 17:93-100, 2016.-Metabolic syndrome, insulin resistance, diabetes, and dyslipidemia are associated with an increased risk of cardiovascular disease. While excessive erythrocytosis is associated with cardiovascular complications, it is unclear how worsening hypoxemia of any degree affects cardiometabolic risk factors in high-altitude populations...
June 2016: High Altitude Medicine & Biology
Laura Gochicoa-Rangel, José Rogelio Pérez-Padilla, Luis Rodríguez-Moreno, Arturo Montero-Matamoros, Nancy Ojeda-Luna, Gema Martínez-Carbajal, Roberto Hernández-Raygoza, Dolores Ruiz-Pedraza, María Rosario Fernández-Plata, Luis Torre-Bouscoulet
BACKGROUND: Altitude above sea level and body mass index are well-recognized determinants of oxygen saturation in adult populations; however, the contribution of these factors to oxygen saturation in children is less clear. OBJECTIVE: To explore the contribution of altitude above sea level and body mass index to oxygen saturation in children. METHODS: A multi-center, cross-sectional study conducted in nine cities in Mexico. Parents signed informed consent forms and completed a health status questionnaire...
November 2015: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Tsering Norboo, Tsering Stobdan, Norboo Tsering, Norboo Angchuk, Phunsog Tsering, Iqbal Ahmed, Tsewang Chorol, Vijay Kumar Sharma, Prasanna Reddy, Shashi Bala Singh, Yumi Kimura, Ryota Sakamoto, Eriko Fukutomi, Motonao Ishikawa, Kuniaki Suwa, Yasuyuki Kosaka, Mitsuhiro Nose, Takayoshi Yamaguchi, Toshihiro Tsukihara, Kozo Matsubayashi, Kuniaki Otsuka, Kiyohito Okumiya
OBJECTIVE: Prevalence of hypertension was examined in a widely dispersed (45 110 km(2)) representative group of Ladakhi in Northern India. The influence of hypoxic environment of wide-ranged altitude (2600-4900 m) and lifestyle change on hypertension was studied. METHODS: 2800 participants (age 20-94 years) were enrolled. Systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure of ≥90 mm Hg and/or taking current anti-hypertensive medicine was defined as hypertension...
April 20, 2015: BMJ Open
Tai-Yi Hsu, Yi-Ming Weng, Yu-Hui Chiu, Wen-Cheng Li, Pang-Yen Chen, Shih-Hao Wang, Kuo-Feng Huang, Wei-Fong Kao, Te-Fa Chiu, Jih-Chang Chen
OBJECTIVE: To examine the effect of ascent rate on the induction of acute mountain sickness (AMS) in young adults during a climb to Jiaming Lake (3350 m) in Taiwan. DESIGN: Prospective, nonrandomized. SETTING: Climb from 2370 to 3350 m. PARTICIPANTS: Young adults (aged 18 to 26 years) (N = 91) chose to participate in either the fast ascent (3 days; n = 43) or slow ascent (4 days; n = 48) group (1 and 2). ASSESSMENT OF RISK FACTORS: Two criteria were used to define AMS...
March 2015: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
Heikki M Karinen, Juha E Peltonen, Mika Kähönen, Heikki O Tikkanen
Acute mountain sickness (AMS) is a common problem while ascending at high altitude. AMS may progress rapidly to fatal results if the acclimatization process fails or symptoms are neglected and the ascent continues. Extensively reduced arterial oxygen saturation at rest (R-Spo₂) has been proposed as an indicator of inadequate acclimatization and impending AMS. We hypothesized that climbers less likely to develop AMS on further ascent would have higher Spo₂ immediately after exercise (Ex-Spo₂) at high altitudes than their counterparts and that these postexercise measurements would provide additional value for resting measurements to plan safe ascent...
2010: High Altitude Medicine & Biology
Sushil Kumar, Saurabh Sharma, Tsering Norboo, Diskit Dolma, Angchuk Norboo, Tsering Stobdan, S Rohatgi, K Munot, Vineet Ahuja, Anoop Saraya
AIM: We did a population-based cross-sectional study to investigate the prevalence and risk factors of gastroesophageal reflux disease (GERD) in a high altitude area. METHODS: An observational study using a validated questionnaire consisting of demographic, lifestyle and dietary characteristics was administered in an interview based format by two clinicians on a sample of adult population residing in urban area and rural high altitude areas of Ladakh. Presence of GERD was defined as a score of ≥4 using a previously validated symptom score based on the severity and frequency of heartburn and regurgitation...
May 2011: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
G F Gonzales, A Villena
OBJECTIVE: The present study was designed to determine if low pulse oxygen saturation (SpO(2)) in post-menopausal women at high altitude was related to high serum testosterone/estradiol (T/E(2)) ratio. METHOD: Studies were carried out in 191 women living in Cerro de Pasco, Peru (4340 m above sea level) and in 56 women living in Lima (150 m asl). Body weight, height, SpO(2), hematocrit, serum follicle stimulating hormone (FSH), T and E(2) levels were measured in all women...
November 2000: International Journal of Gynaecology and Obstetrics
C M Beall, L A Almasy, J Blangero, S Williams-Blangero, G M Brittenham, K P Strohl, M J Decker, E Vargas, M Villena, R Soria, A M Alarcon, C Gonzales
A range of variation in percent of oxygen saturation of arterial hemoglobin (SaO2) among healthy individuals at a given high altitude indicates differences in physiological hypoxemia despite uniform ambient hypoxic stress. In populations native to the Tibetan plateau, a significant portion of the variance is attributable to additive genetic factors, and there is a major gene influencing SaO2. To determine whether there is genetic variance in other high-altitude populations, we designed a study to test the hypothesis that additive genetic factors contribute to phenotypic variation in SaO2 among Aymara natives of the Andean plateau, a population geographically distant from the Tibetan plateau and with a long, separate history of high-altitude residence...
January 1999: American Journal of Physical Anthropology
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