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Oncofertility

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https://www.readbyqxmd.com/read/29298112/antineoplastic-agents-and-in-fertility-informing-patients-to-improve-decisions
#1
Cristina Silva, Ana Teresa Almeida-Santos, Cláudia Melo, Ana Cristina Ribeiro Rama
PURPOSE: Infertility is a potential adverse effect of cancer treatment, and future fertility is an important issue for cancer patients. In Portugal, the Centre for Fertility Preservation of CHUC, EPE, conducted a project to develop and disseminate oncofertility information resources. In this study, we report the results of the specific component of this program, which intended to produce information resources that promote patients' awareness of the subject and to support decisions concerning fertility preservation...
January 3, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29259484/semen-cryopreservation-as-an-oncofertility-treatment-in-122-japanese-men-with-cancer-a-decade-long-study
#2
Hideyuki Kobayashi, Koji Tamura, Toshihiro Tai, Koichi Nagao, Koichi Nakajima
Purpose: Oncofertility is a subspecialty that is concerned with helping patients with cancer preserve their ability to have children in the future. For men, sperm banking is an established way to preserve fertility. The aim was to determine the prefreeze semen characteristics and reproductive outcomes according to cancer type for men who chose semen cryopreservation. Methods: The records of 122 men with cancer who requested semen cryopreservation at the authors' hospital from 2006 to 2015 were reviewed...
October 2017: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29220203/recent-advances-in-fertility-preservation-and-counseling-for-female-cancer-patients
#3
Marie-Madeleine Dolmans
Ensuring quality of life for increasing numbers of women surviving cancer has become a key challenge. Patients need to be counseled on potential fertility loss resulting from gonadotoxic treatments, and referred to fertility specialists to discuss existing options and available results. Areas covered: Fertility preservation options have existed for over twenty years. The proposed fertility preservation approach depends on patient age, the urgency of required chemotherapy, and psychosocial factors such as financial concerns, especially in countries where techniques are not covered by social security...
December 8, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29216337/brca-1-and-2-mutation-status-the-elephant-in-the-room-during-oncofertility-counseling-for-young-breast-cancer-patients
#4
S Paluch-Shimon, F A Peccatori
No abstract text is available yet for this article.
December 5, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29186987/perurethral-transvesical-route-for-oocytes-retrieval-an-old-technique-for-a-new-indication-in-oncofertility
#5
Mohamed Khrouf, Marouen Braham, Maha Bouyahia, Khadija Kacem-Berejeb, Hanène Elloumi-Chaabane, Amel Zhioua, Fethi Zhioua
We aimed to evaluate the safety and efficiency of the peruretheral transvesical oocyte retrieval in oncofertility. We conducted a retrospective comparative study in our assisted reproductive technologies center. STUDY GROUP: 28 pubertal young women affected by malignancies, referred for fertility preservation and refusing transvaginal (TV) procedure. CONTROL GROUP: 28 infertile patients, aged less than 25 years, who have undergone in vitro fertilization with TV oocyte retrieval...
December 2017: Future Oncology
https://www.readbyqxmd.com/read/29184796/oncofertility-in-sarcoma-patients
#6
REVIEW
Diana M Lopategui, Raphael Yechieli, Ranjith Ramasamy
Treatment for sarcoma can significantly decrease fertility, both due to the irradiation of gonads, and the impact of chemotherapy on gametogenesis. Infertility in cancer survivors causes significant regret and decreased quality of life in their adulthood. As this cancer mainly affects children and young adults, fertility preservation is an essential part of survivorship care, however it remains one of the least implemented services in adolescent and young adult cancer patients. Success of fertility preservation is highly dependent on the referral prior to oncologic treatment...
October 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29058500/recall-of-fertility-discussion-by-adolescent-female-cancer-patients-a-survey-based-pilot-study
#7
Sara Zarnegar, Yasmin Gosiengfiao, Alfred Rademaker, Robert Casey, Karen H Albritton
Many adolescent female cancer patients will survive into their reproductive years. Pediatric oncologists are advised to discuss oncofertility during treatment planning. In this pilot study, 19 adolescent females completed a retrospective survey assessing recall of a fertility discussion, satisfaction with fertility knowledge, and multiple factors that may influence recall, including parental involvement in decision-making. Eleven respondents (58%) remembered a discussion about infertility risk and 9 (47%) about fertility preservation...
October 23, 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29056646/nib-commentary-on-oncofertility-stories
#8
Becket Gremmels
The authors of these stories describe tales of struggle with cancer and secondary infertility. Yet, they each have a different response to similar circumstances. Their stories touch on a lack of informed consent regarding infertility, spiritual discussions of the problem of evil, the need for improved collaboration among physicians to further care of the whole person, societal norms regarding reproduction and gender roles, the injustice of cancer in young people, and other topics. Of note, no stories mention prominent ethical concerns of in-vitro fertilization like how couples should deal with "extra" frozen embryos or concerns about the potential for commodification of children...
2017: Narrative Inquiry in Bioethics
https://www.readbyqxmd.com/read/29056645/fertility-lost-fertility-found-narratives-from-the-leading-edge-of-oncofertility
#9
Teresa K Woodruff
A cancer diagnosis at a young age creates one of the most existential crises one can imagine. The good news is that for many of these young patients, they will survive their diagnosis. They will be told of the side effects of treatment including loss of hair but will not be told of the other losses associated with their reproductive function-loss of menstrual cycles, early menopause and the potential for pregnancy for women, loss of viable sperm for men, and loss of sexual libido in both cases. Not all cancer treatments result in the same series of fertility effects so one of the issues that physicians face is determining what the best course of fertility sparing options should be...
2017: Narrative Inquiry in Bioethics
https://www.readbyqxmd.com/read/29056630/cancer-and-fertility
#10
Ana S Iltis
This symposium includes 12 personal narratives from individuals who have faced a cancer diagnosis-either their own or their child's-where the disease itself, or their treatment, threatened future fertility. Three additional stories are available in the online supplement. Three commentaries on these narratives are written by an expert in oncofertility, a healthcare ethicist, and a pediatrician completing a fellowship in hematology/oncology. The observations and insights these authors share underscore the importance of addressing fertility loss and preservation early in the cancer journey...
2017: Narrative Inquiry in Bioethics
https://www.readbyqxmd.com/read/28959743/new-promising-strategies-in-oncofertility
#11
Janella N Hudson, Nathanael B Stanley, Leena Nahata, Meghan Bowman-Curci, Gwendolyn P Quinn
INTRODUCTION: Approximately 70,000 adolescent and young adults (AYA) are diagnosed with cancer each year. While advancements in treatment have led to improved prognosis and survival for patients, these same treatments can adversely affect AYA reproductive capacity. Localized treatments such as surgery and radiation therapy may affect fertility by removing or damaging reproductive organs, and systemic therapies such as chemotherapy can be toxic to gonads, (ovaries and testicles), thus affecting fertility and/or endocrine function...
2017: Expert Review of Quality of Life in Cancer Care
https://www.readbyqxmd.com/read/28949840/adolescent-oncofertility-discussions-recommendations-from-a-systematic-literature-review
#12
Dorit Barlevy, Bernice S Elger, Tenzin Wangmo, Vardit Ravitsky
BACKGROUND: Increasing cancer incidence and survivorship rates have made late-term effects, such as effects on fertility, a salient issue for adolescent cancer patients. While various barriers make it difficult for health care professionals to discuss oncofertility with adolescents and their parents, there are numerous reasons to hold such discussions, based on professional obligations and the ethical principles of respect for autonomy and beneficence. This systematic literature review presents and critically examines recommendations for adolescent oncofertility discussions...
April 2017: AJOB Empirical Bioethics
https://www.readbyqxmd.com/read/28806962/oncofertility-in-patients-with-stage-i-epithelial-ovarian-cancer-fertility-sparing-surgery-in-young-women-of-reproductive-age
#13
Xuan Jiang, Jiaxin Yang, Mei Yu, Weimin Xie, Dongyan Cao, Ming Wu, Lingya Pan, Huifang Huang, Yan You, Keng Shen
BACKGROUND: Fertility-sparing surgery is indicated for patients with stage I epithelial ovarian cancers. We sought to evaluate the clinical outcomes and oncofertility in a cohort of patients of reproductive age with stage I epithelial ovarian cancer (EOC). METHODS: Overall, 108 patients of reproductive age (≤ 40 years) diagnosed with stage I EOC who were treated at Peking Union Medical College Hospital between 1999 and 2013 were included in the study. The Kaplan-Meier model and Cox regression analyses were used for the survival analysis...
August 15, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28762627/clinician-provision-of-oncofertility-support-in-cancer-patients-of-a-reproductive-age-a-systematic-review
#14
REVIEW
S Logan, J Perz, J Ussher, M Peate, A Anazodo
OBJECTIVE: The emerging discipline of oncofertility advocates for the timely provision of fertility information and referral for fertility preservation to all cancer patients of reproductive age (<45 years). A systematic review was undertaken on the clinician provision of oncofertility support to determine whether cancer patients are having their support needs adequately met by staff. METHODS: An initial search conducted in May 2016 identified 351 potentially relevant studies...
August 1, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28750297/fertility-and-pregnancy-issues-in-brca-mutated-breast-cancer-patients
#15
REVIEW
Matteo Lambertini, Oranite Goldrat, Angela Toss, Hatem A Azim, Fedro A Peccatori, Michail Ignatiadis, Lucia Del Mastro, Isabelle Demeestere
Fertility and pregnancy-related issues represent one of the main areas of concerns for young women with breast cancer. Carrying a germline deleterious BRCA mutation adds additional burden on this regard due to the specific issues that should be considered during the oncofertility counseling of this special patient group. Despite the availability of a growing amount of data in the general breast cancer population on the feasibility and safety of fertility preservation and pregnancy after diagnosis, numerous challenges remain for BRCA-mutated breast cancer patients in whom very limited studies have been performed so far...
September 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28734119/a-systematic-review-of-patient-oncofertility-support-needs-in-reproductive-cancer-patients-aged-14-to-45-years-of-age
#16
REVIEW
S Logan, J Perz, J M Ussher, M Peate, A Anazodo
OBJECTIVE: Decline in fertility potential brought about by a cancer diagnosis or cancer treatment is one of the biggest impacts to cancer patients' long term quality of life. As such, the current manuscript aimed to systematically review the literature on oncofertility support needs for cancer patients of a reproductive age (14-45 years of age). METHODS: A systematic review of the literature was conducted in May 2016 through the searching of electronic databases Medline, EMBASE, PSYCH Info, Web of Science and SCOPUS, alongside the screening of relevant reference lists...
July 22, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28725849/the-role-of-oncofertility-clinics-in-facilitating-access-to-reproductive-specialists
#17
Eduardo Hariton, Pietro Bortoletto, Eden R Cardozo, Ephraim P Hochberg, Mary E Sabatini
PURPOSE: To determine the impact of the establishment of a dedicated oncofertility clinic on the frequency of patient referrals for fertility preservation (FP) consultation and the time from patient referral to consultation. METHODS: A retrospective chart review of all women aged 21 to 44 years with an active cancer diagnosis who were referred for FP consultation from 2011 to 2015. RESULTS: A total of 6895 female patients eligible for FP were seen at the Massachusetts General Hospital (MGH) Cancer Center...
December 2016: Journal of Patient Experience
https://www.readbyqxmd.com/read/28667545/what-is-the-role-of-the-oncology-nurse-in-fertility-preservation-counseling-and-education-for-young-patients
#18
Jessica Keim-Malpass, Hannah S Fitzhugh, Laura P Smith, Ryan P Smith, Jeanne Erickson, Mike G Douvas, Tanya Thomas, Gina Petroni, Linda Duska
Oncology nurses are uniquely positioned to offer fertility preservation counseling and education for cancer patients of reproductive age, yet there is a dearth of research that focuses on current practice and perceptions of nursing role. In 2013, the American Society of Clinical Oncology extended the duties of fertility preservation counseling among patients of reproductive age undergoing cancer treatment to include registered nurses and other allied health professionals as active partners in the counseling and education process...
July 1, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28657411/recommendations-of-the-fertility-preservation-working-group-in-oncological-hematological-and-other-patients-treated-with-gonadotoxic-therapies-oncofertility-grof-of-the-polish-society-of-oncological-gynecology
#19
Robert Jach, Wojciech Pabian, Robert Spaczyński, Jacek Szamatowicz, Tomasz Zbroch, Paweł Knapp, Roman Smolarczyk, Wojciech Kolawa, Lubomir Bodnar, Rafał Kurzawa, Daria Zawirska, Maciej Krzakowski, Stanisław Radowicki, Jacek Fijuth, Mirosław Wielgoś, Piotr Wysocki, Katarzyna Kozioł, Kamil Zalewski, Krzysztof Warzocha, Kazimierz Hałaburda, Michał Rdwan, Paweł Radwan, Marcin Jacek Jabłoński, Zbigniew Kojs, Sławomir Wołczyński, Leszek Pawelczyk, Tomasz Kluz
No abstract text is available yet for this article.
September 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28609273/knowledge-regarding-fertility-preservation-in-cancer-patients-a-population-based-survey-among-brazilian-people-during-the-pink-october-awareness-event
#20
Mauricio B Chehin, Tatiana Cs Bonetti, Paulo C Serafini, Eduardo LA Motta
OBJECTIVE: The aim of this study was to assess the knowledge about the risk of infertility in cancer patients after treatment, and the options for fertility preservation based on a survey carried out during the 2013 Pink October campaign. METHODS: This survey was carried out during the 2013 Pink October event in the most important public park of São Paulo, Brazil. Approximately 900 people expressed interest in learning about breast cancer prevention and fertility preservation by participating in workshops, and 242 people filled out a questionnaire...
June 1, 2017: JBRA Assisted Reproduction
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