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Oncofertility

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https://www.readbyqxmd.com/read/29974370/fertility-preservation-in-women-with-cancer-a-national-study-about-french-oncologists-awareness-experience-and-feelings
#1
Amira Sallem, Joanna Shore, Isabelle Ray-Coquard, Lucile Ferreux, Mathilde Bourdon, Chloé Maignien, Catherine Patrat, Jean-Philippe Wolf, Khaled Pocate-Cheriet
PURPOSE: This study was designed to evaluate patient management and quality of information given by French oncologists to cancer women concerning fertility issues and possibilities of fertility preservation. METHODS: An online survey was sent to 1161 physicians in all major cancer centers throughout France between May 2012 and January 2013. RESULTS: A total of 102 responses were received and analyzed. Only 46% of all physicians surveyed reported discussing infertility risks with patients of reproductive age and 22% referred them to a fertility center before beginning treatments...
July 4, 2018: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29972282/oncofertility-an-emerging-discipline-rather-than-a-special-consideration
#2
REVIEW
Antoinette Anazodo, Lauren Ataman-Millhouse, Yasmin Jayasinghe, Teresa K Woodruff
Originally absent from the oncologist's consult, then placed in a 'quality of life' rubric, oncofertility should now be an essential part of a comprehensive cancer treatment plan in patients of reproductive age, including adolescents and young adults (AYAs). Oncofertility encompasses the endocrine health of the patient, as well as fertility management options. Thus, pubertal transitions in males and females, bone health, and menstrual health are all part of this discipline, enabling practitioners to work in interdisciplinary teams to solve problems in reproductive health...
July 3, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29938339/creation-and-evaluation-of-a-cancer-survivorship-curriculum-for-pediatric-resident-physicians
#3
Lindsay F Schwartz, Clarence H Braddock, Roy L Kao, Myung-Shin Sim, Jacqueline N Casillas
PURPOSE: There is a paucity of formal clinician education concerning cancer survivorship care, which produces care barriers and poorer outcomes for survivors of childhood cancer. To address this, we implemented a curriculum in childhood cancer survivorship care for pediatric residents at the University of California, Los Angeles (UCLA). We examined the efficacy of this curriculum following program completion. METHODS: A case-based curriculum was created and integrated within existing educational structures using Kern's model...
June 25, 2018: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/29845104/oncofertility-in-the-setting-of-advanced-cervical-cancer-a-case-report
#4
Catherine Gordon, Joseph C Carmichael, Krishnansu S Tewari
Objective: To consider fertility options in women with advanced cervical cancer. Design: Case report. Setting: Large tertiary care center. Patient: A 30-year-old nulligravida woman diagnosed with FIGO Stage IBI squamous cell carcinoma of the cervix that had metastasized to a pelvic lymph node. Interventions: Robotic radical trachelectomy with pelvic lymphadenectomy and cerclage placement, followed by ovarian stimulation with oocyte retrieval and in vitro fertilization...
May 2018: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/29733237/a-clinical-decision-support-system-to-assist-pediatric-oncofertility-a-short-report
#5
Meredith Hand, Matthew A Kemertzis, Michelle Peate, Lynn Gillam, Maria McCarthy, Lisa Orme, Yves Heloury, Michael Sullivan, Margaret Zacharin, Yasmin Jayasinghe
PURPOSE: Fertility preservation discussions with pediatric and adolescent cancer patients can be difficult for clinicians. This study describes the acceptability of a fertility clinician decision support system (CDSS). METHODS: A cross-sectional study of clinicians at The Royal Children's Hospital, Melbourne. Participants were trained on CDSS purpose, contents, and use. A survey captured the perceived benefits and weaknesses of the CDSS. RESULTS: Thirty-nine clinicians participated...
May 7, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29672191/knowledge-and-beliefs-about-oncofertility-and-associations-with-quality-of-life-among-adolescent-and-young-adult-survivors-of-pediatric-cancer
#6
Andrea C Johnson, Darren Mays, Kathryn Rehberg, Aziza Shad, Kenneth P Tercyak
PURPOSE: Adolescent and young adult (AYA) cancer survivors experience fertility and childrearing challenges in adulthood, but there is limited evidence on awareness, beliefs, and concerns about oncofertility in this population, needs for supportive resources, and associations with quality of life (QoL). METHODS: Participants were 69 AYAs aged 12-25 who were diagnosed with cancer at age 18 years or younger and ≥1 year cancer free, recruited from childhood cancer clinical records and support organizations...
April 19, 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29610538/new-approaches-in-cancer-biology-can-inform-the-biology-curriculum
#7
Lynda Jones, Diana Gordon, Mary Zelinski
Students tend to be very interested in medical issues that affect them and their friends and family. Using cancer as a hook, the ART of Reproductive Medicine: Oncofertility curriculum (free, online, and NIH sponsored) has been developed to supplement the teaching of basic biological concepts and to connect biology and biomedical research. This approach allows integration of up-to-date information on cancer and cancer treatment, cell division, male and female reproductive anatomy and physiology, cryopreservation, fertility preservation, stem cells, ethics, and epigenetics into an existing biology curriculum...
March 2018: American Biology Teacher
https://www.readbyqxmd.com/read/29502284/fertility-preservation-for-female-cancer-patients
#8
REVIEW
Miyuki Harada, Yutaka Osuga
An improvement in the survival rates of cancer patients and recent advancements in assisted reproductive technologies have led to remarkable progress in oncofertility and fertility preservation treatments. Currently, for adults and postpubertal girls, oocyte or embryo cryopreservation is an established method. If their cancer treatment cannot be postponed for 2 weeks, ovarian tissue cryopreservation is offered as an experimental technique. For prepubertal girls, ovarian tissue cryopreservation is the only option...
March 3, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29481385/fertility-preservation-toolkit-a-clinician-resource-to-assist-clinical-discussion-and-decision-making-in-pediatric-and-adolescent-oncology
#9
Matthew A Kemertzis, Harene Ranjithakumaran, Meredith Hand, Michelle Peate, Lynn Gillam, Maria McCarthy, Leanne Super, Sarah McQuillan, Sarah Drew, Yasmin Jayasinghe, Lisa Orme
PURPOSE: Fertility preservation (FP) discussions in children with cancer presents unique challenges due to ethical considerations, lack of models-of-care, and the triadic nature of discussions. This study evaluated a fertility toolkit for clinicians involved in FP discussions with pediatric, adolescent, and young adult patients and parents. MATERIALS AND METHODS: A survey-based, longitudinal study of clinicians at The Royal Children's Hospital Melbourne involved in FP discussions undertaken at 3 time-points: 2014, alongside an education session for baseline assessment of oncofertility practices (survey 1); after each toolkit use to evaluate case-specific implementation (survey 2); 2016, to evaluate impact on clinical practice (survey 3)...
April 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29452595/fertility-preservation-healthcare-circuit-and-networks-in-cancer-patients-worldwide-what-are-the-issues
#10
REVIEW
Kathleen Melan, Frederic Amant, Jacqueline Veronique-Baudin, Clarisse Joachim, Eustase Janky
BACKGROUND: Fertility preservation (FP) is a major determinant of quality of life after cancer remission for women who may not have achieved their ideal family size. This article describes the FP services and strategy currently available, highlighting issues of oncofertility worldwide. For these patients in complex situations, health networks are essential to improve coordination of care, and the strengthening of this coordination is a major challenge to improve the performance of the health system...
February 17, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29424241/the-challenges-of-fertility-preservation-in-cancer-patients-an-interview-with-michael-grynberg
#11
Michael Grynberg
Michaël Grynberg is an Obstetrician Gynecologist specialized in reproductive medicine. After 1 year as a visiting fellow in the Department of Reproductive Medicine at Cornell University, he returned to work in France as an Attending Physician in the Division of Reproductive Medicine at the University Hospital Antoine Béclère, Clamart, France. In 2011, he completed his PhD on the topic of the regulation of follicular growth and anti-Müllerian hormone production. Since 2014, he has been Professor of Reproductive Medicine and the Head of the Department of Reproductive Medicine and Fertility Preservation at the University Hospital Jean Verdier, Bondy, France...
March 2018: Future Oncology
https://www.readbyqxmd.com/read/29376012/fertility-preservation-during-cancer-treatment-the-korean-society-for-fertility-preservation-clinical-guidelines
#12
REVIEW
Jayeon Kim, Seul Ki Kim, Kyung Joo Hwang, Seok Hyun Kim
While many fertility preservation (FP) options now exist for reproductive-aged cancer patients, access to these services continues to be limited. A comprehensive FP program should be organized to serve oncofertility patients effectively. Also, much effort is needed from various individuals-patients, specialists from various fields, and consultants-to facilitate FP in a timely manner. Various challenges still exist in improving access to FP programs. To improve access to FP treatment, it is important to educate oncologists and patients via electronic tools and to actively navigate patients through the system...
December 2017: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/29345507/ovarian-tissue-cryopreservation-in-young-females-through-the-oncofertility-consortium-s-national-physicians-cooperative
#13
Austin G Armstrong, Bruce F Kimler, Brigid M Smith, Teresa K Woodruff, Mary Ellen Pavone, Francesca E Duncan
AIM: To characterize the clinical indications of females (<15 years old) undergoing ovarian tissue cryopreservation (OTC) through the Oncofertility Consortium's National Physicians Cooperative (OC-NPC). PATIENTS & METHODS: The clinical indications of 114 females who underwent OTC were classified, and their incidence was compared with childhood cancer databases. RESULTS: Leukemias/myeloproliferative diseases/myelodysplastic diseases and hemoglobinopathies were the most prevalent oncologic and nononcologic indications for OTC, respectively...
January 18, 2018: Future Oncology
https://www.readbyqxmd.com/read/29298112/antineoplastic-agents-and-in-fertility-informing-patients-to-improve-decisions
#14
Cristina Silva, Ana Teresa Almeida-Santos, Cláudia Melo, Ana Cristina Ribeiro Rama
PURPOSE: Infertility is a potential adverse effect of cancer treatment, and future fertility is an important issue for cancer patients. In Portugal, the Centre for Fertility Preservation of CHUC, EPE, conducted a project to develop and disseminate oncofertility information resources. In this study, we report the results of the specific component of this program, which intended to produce information resources that promote patients' awareness of the subject and to support decisions concerning fertility preservation...
June 2018: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/29259484/semen-cryopreservation-as-an-oncofertility-treatment-in-122-japanese-men-with-cancer-a-decade-long-study
#15
Hideyuki Kobayashi, Koji Tamura, Toshihiro Tai, Koichi Nagao, Koichi Nakajima
Purpose: Oncofertility is a subspecialty that is concerned with helping patients with cancer preserve their ability to have children in the future. For men, sperm banking is an established way to preserve fertility. The aim was to determine the prefreeze semen characteristics and reproductive outcomes according to cancer type for men who chose semen cryopreservation. Methods: The records of 122 men with cancer who requested semen cryopreservation at the authors' hospital from 2006 to 2015 were reviewed...
October 2017: Reproductive Medicine and Biology
https://www.readbyqxmd.com/read/29220203/recent-advances-in-fertility-preservation-and-counseling-for-female-cancer-patients
#16
Marie-Madeleine Dolmans
Ensuring quality of life for increasing numbers of women surviving cancer has become a key challenge. Patients need to be counseled on potential fertility loss resulting from gonadotoxic treatments, and referred to fertility specialists to discuss existing options and available results. Areas covered: Fertility preservation options have existed for over twenty years. The proposed fertility preservation approach depends on patient age, the urgency of required chemotherapy, and psychosocial factors such as financial concerns, especially in countries where techniques are not covered by social security...
February 2018: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/29216337/brca-1-and-2-mutation-status-the-elephant-in-the-room-during-oncofertility-counseling-for-young-breast-cancer-patients
#17
S Paluch-Shimon, F A Peccatori
No abstract text is available yet for this article.
January 1, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29186987/perurethral-transvesical-route-for-oocytes-retrieval-an-old-technique-for-a-new-indication-in-oncofertility
#18
Mohamed Khrouf, Marouen Braham, Maha Bouyahia, Khadija Kacem-Berejeb, Hanène Elloumi-Chaabane, Amel Zhioua, Fethi Zhioua
We aimed to evaluate the safety and efficiency of the peruretheral transvesical oocyte retrieval in oncofertility. We conducted a retrospective comparative study in our assisted reproductive technologies center. STUDY GROUP: 28 pubertal young women affected by malignancies, referred for fertility preservation and refusing transvaginal (TV) procedure. CONTROL GROUP: 28 infertile patients, aged less than 25 years, who have undergone in vitro fertilization with TV oocyte retrieval...
December 2017: Future Oncology
https://www.readbyqxmd.com/read/29184796/oncofertility-in-sarcoma-patients
#19
REVIEW
Diana M Lopategui, Raphael Yechieli, Ranjith Ramasamy
Treatment for sarcoma can significantly decrease fertility, both due to the irradiation of gonads, and the impact of chemotherapy on gametogenesis. Infertility in cancer survivors causes significant regret and decreased quality of life in their adulthood. As this cancer mainly affects children and young adults, fertility preservation is an essential part of survivorship care, however it remains one of the least implemented services in adolescent and young adult cancer patients. Success of fertility preservation is highly dependent on the referral prior to oncologic treatment...
October 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29058500/recall-of-fertility-discussion-by-adolescent-female-cancer-patients-a-survey-based-pilot-study
#20
Sara Zarnegar, Yasmin Gosiengfiao, Alfred Rademaker, Robert Casey, Karen H Albritton
Many adolescent female cancer patients will survive into their reproductive years. Pediatric oncologists are advised to discuss oncofertility during treatment planning. In this pilot study, 19 adolescent females completed a retrospective survey assessing recall of a fertility discussion, satisfaction with fertility knowledge, and multiple factors that may influence recall, including parental involvement in decision-making. Eleven respondents (58%) remembered a discussion about infertility risk and 9 (47%) about fertility preservation...
April 2018: Journal of Adolescent and Young Adult Oncology
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