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Oncofertility

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https://www.readbyqxmd.com/read/28806962/oncofertility-in-patients-with-stage-i-epithelial-ovarian-cancer-fertility-sparing-surgery-in-young-women-of-reproductive-age
#1
Xuan Jiang, Jiaxin Yang, Mei Yu, Weimin Xie, Dongyan Cao, Ming Wu, Lingya Pan, Huifang Huang, Yan You, Keng Shen
BACKGROUND: Fertility-sparing surgery is indicated for patients with stage I epithelial ovarian cancers. We sought to evaluate the clinical outcomes and oncofertility in a cohort of patients of reproductive age with stage I epithelial ovarian cancer (EOC). METHODS: Overall, 108 patients of reproductive age (≤ 40 years) diagnosed with stage I EOC who were treated at Peking Union Medical College Hospital between 1999 and 2013 were included in the study. The Kaplan-Meier model and Cox regression analyses were used for the survival analysis...
August 15, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28762627/clinician-provision-of-oncofertility-support-in-cancer-patients-of-a-reproductive-age-a-systematic-review
#2
REVIEW
S Logan, J Perz, J Ussher, M Peate, A Anazodo
OBJECTIVE: The emerging discipline of oncofertility advocates for the timely provision of fertility information and referral for fertility preservation to all cancer patients of reproductive age (<45 years). A systematic review was undertaken on the clinician provision of oncofertility support to determine whether cancer patients are having their support needs adequately met by staff. METHODS: An initial search conducted in May 2016 identified 351 potentially relevant studies...
August 1, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28750297/fertility-and-pregnancy-issues-in-brca-mutated-breast-cancer-patients
#3
REVIEW
Matteo Lambertini, Oranite Goldrat, Angela Toss, Hatem A Azim, Fedro A Peccatori, Michail Ignatiadis, Lucia Del Mastro, Isabelle Demeestere
Fertility and pregnancy-related issues represent one of the main areas of concerns for young women with breast cancer. Carrying a germline deleterious BRCA mutation adds additional burden on this regard due to the specific issues that should be considered during the oncofertility counseling of this special patient group. Despite the availability of a growing amount of data in the general breast cancer population on the feasibility and safety of fertility preservation and pregnancy after diagnosis, numerous challenges remain for BRCA-mutated breast cancer patients in whom very limited studies have been performed so far...
September 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28734119/a-systematic-review-of-patient-oncofertility-support-needs-in-reproductive-cancer-patients-aged-14-to-45-years-of-age
#4
REVIEW
S Logan, J Perz, J M Ussher, M Peate, A Anazodo
OBJECTIVE: Decline in fertility potential brought about by a cancer diagnosis or cancer treatment is one of the biggest impacts to cancer patients' long term quality of life. As such, the current manuscript aimed to systematically review the literature on oncofertility support needs for cancer patients of a reproductive age (14-45 years of age). METHODS: A systematic review of the literature was conducted in May 2016 through the searching of electronic databases Medline, EMBASE, PSYCH Info, Web of Science and SCOPUS, alongside the screening of relevant reference lists...
July 22, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28725849/the-role-of-oncofertility-clinics-in-facilitating-access-to-reproductive-specialists
#5
Eduardo Hariton, Pietro Bortoletto, Eden R Cardozo, Ephraim P Hochberg, Mary E Sabatini
PURPOSE: To determine the impact of the establishment of a dedicated oncofertility clinic on the frequency of patient referrals for fertility preservation (FP) consultation and the time from patient referral to consultation. METHODS: A retrospective chart review of all women aged 21 to 44 years with an active cancer diagnosis who were referred for FP consultation from 2011 to 2015. RESULTS: A total of 6895 female patients eligible for FP were seen at the Massachusetts General Hospital (MGH) Cancer Center...
December 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28667545/what-is-the-role-of-the-oncology-nurse-in-fertility-preservation-counseling-and-education-for-young-patients
#6
Jessica Keim-Malpass, Hannah S Fitzhugh, Laura P Smith, Ryan P Smith, Jeanne Erickson, Mike G Douvas, Tanya Thomas, Gina Petroni, Linda Duska
Oncology nurses are uniquely positioned to offer fertility preservation counseling and education for cancer patients of reproductive age, yet there is a dearth of research that focuses on current practice and perceptions of nursing role. In 2013, the American Society of Clinical Oncology extended the duties of fertility preservation counseling among patients of reproductive age undergoing cancer treatment to include registered nurses and other allied health professionals as active partners in the counseling and education process...
July 1, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28657411/recommendations-of-the-fertility-preservation-working-group-in-oncological-hematological-and-other-patients-treated-with-gonadotoxic-therapies-oncofertility-grof-of-the-polish-society-of-oncological-gynecology
#7
Robert Jach, Wojciech Pabian, Robert Spaczyński, Jacek Szamatowicz, Tomasz Zbroch, Paweł Knapp, Roman Smolarczyk, Wojciech Kolawa, Lubomir Bodnar, Rafał Kurzawa, Daria Zawirska, Maciej Krzakowski, Stanisław Radowicki, Jacek Fijuth, Mirosław Wielgoś, Piotr Wysocki, Katarzyna Kozioł, Kamil Zalewski, Krzysztof Warzocha, Kazimierz Hałaburda, Michał Rdwan, Paweł Radwan, Marcin Jacek Jabłoński, Zbigniew Kojs, Sławomir Wołczyński, Leszek Pawelczyk, Tomasz Kluz
No abstract text is available yet for this article.
September 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28609273/knowledge-regarding-fertility-preservation-in-cancer-patients-a-population-based-survey-among-brazilian-people-during-the-pink-october-awareness-event
#8
Mauricio B Chehin, Tatiana Cs Bonetti, Paulo C Serafini, Eduardo LA Motta
OBJECTIVE: The aim of this study was to assess the knowledge about the risk of infertility in cancer patients after treatment, and the options for fertility preservation based on a survey carried out during the 2013 Pink October campaign. METHODS: This survey was carried out during the 2013 Pink October event in the most important public park of São Paulo, Brazil. Approximately 900 people expressed interest in learning about breast cancer prevention and fertility preservation by participating in workshops, and 242 people filled out a questionnaire...
June 1, 2017: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28575176/global-oncofertility-index-data-gap-slows-progress
#9
Saskia F de Roo, Alexandra S Rashedi, Catharina C M Beerendonk, Antoinette Anazodo, Anne Marie de Man, Willianne L D M Nelen, Teresa K Woodruff
The number of pediatric and young adult cancer survivors is increasing globally due to earlier diagnostics and expansion of targeted chemo- and biological-based therapeutics. As a consequence, cancer-related infertility and reproductive hormone loss is of increasing concern for both male and female survivors. We attempted to estimate the reproductive loss in oncofertility-practicing countries and to develop a global oncofertility index (OFI). This would allow an accounting of the level of urgency of the issue and would provide national comparisons of fertility loss, which differ based on the prevalence and/or diagnosis frequency and treatment variables by countries or region...
June 1, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28551906/-fertility-preservation-in-young-cancer-patients-can-we-optimize-the-path
#10
REVIEW
Irit Ben-Aharon, Shifra Ash, Avi Ben-Haroush, Gali Perl, Galia Oron, Haim Pinkas, Naphtali Freud, Dragan Kravarusic, Ronit Abir, Onit Sapir, Arnon Wiznitzer, Baruch Brenner, Isaac Yaniv, Salomon Stemmer, Benjamin Fisch
INTRODUCTION: Advances in cancer therapy have improved the long-term survival of cancer patients. Concerns about fertility represent a major issue for young cancer patients. The emergent discipline of oncofertility, an intersection between oncology and fertility, is a new concept that describes an integrated network of clinical resources that focus on fertility preservation from both clinical and research perspectives. Patients and methods: In this article we describe our designated multidisciplinary program for fertility preservation in pediatric and young adult populations...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28550713/state-of-the-art-on-oocyte-cryopreservation-in-female-cancer-patients-a-critical-review-of-the-literature
#11
REVIEW
Claudia Massarotti, Paola Scaruffi, Matteo Lambertini, Valentino Remorgida, Lucia Del Mastro, Paola Anserini
During the last decades, important advances in therapeutic options have led to increased survival rates in cancer patients; however, cancer treatments are associated with several potential adverse effects including infertility in those diagnosed during their reproductive years. A proper discussion about fertility preservation options before the use of therapies with potential gonadotoxicity (i.e. oncofertility counseling) is standard of care and should be offered to all patients of childbearing age. Temporary ovarian suppression with LH-RH analogs, oocyte and embryo cryopreservation are standard strategies for fertility preservation in female cancer patients...
June 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/28541787/ethics-and-oncofertility-a-call-for-religious-sensitivity
#12
Michele R Hanselin, Deborah L Roybal, Thomas B Leininger
For patients of reproductive age, treating cancer may come at the price of infertility. Literature regarding fertility preservation recommendations in this population has increased significantly, but this literature too often overlooks or insufficiently considers the relevance of religious preferences. Similarly, practice guidelines do not address the role of religion in the oncofertility discussion. The acceptance of oncofertility practices varies significantly among Christianity, Judaism, and Islam. A patient's faith-based spirituality or secular morality may enhance his or her interpretation of the meaning of illness and should be incorporated into the informed-consent process...
July 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28537815/anticancer-treatments-and-female-fertility-clinical-concerns-and-role-of-oncologists-in-oncofertility-practice
#13
REVIEW
Mahmoud Salama, Teresa K Woodruff
Anticancer treatments such as aggressive chemotherapy and radiotherapy have deleterious gonadotoxic side effects and are considered the most common causes of pathological and iatrogenic fertility loss in women. Areas covered: In order to preserve fertility of young women and girls with cancer, several established, experimental, and debatable options can be offered in the emerging field of oncofertility. This article reviews the effects of anticancer treatments on female fertility and discusses the current challenges and future directions of fertility preservation options that can be offered to the female patients with cancer...
August 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28526012/the-pregnancy-and-fertility-prefer-study-an-italian-multicenter-prospective-cohort-study-on-fertility-preservation-and-pregnancy-issues-in-young-breast-cancer-patients
#14
Matteo Lambertini, Paola Anserini, Valeria Fontana, Francesca Poggio, Giuseppina Iacono, Annalisa Abate, Alessia Levaggi, Loredana Miglietta, Claudia Bighin, Sara Giraudi, Alessia D'Alonzo, Eva Blondeaux, Davide Buffi, Francesco Campone, Domenico F Merlo, Lucia Del Mastro
BACKGROUND: Fertility and pregnancy issues are of key importance for young breast cancer patients. Despite several advances in the field, there are still multiple unmet needs and barriers in discussing and dealing with these concerns. To address the significant challenges related to fertility and pregnancy issues, the PREgnancy and FERtility (PREFER) study was developed as a national comprehensive program aiming to optimize care and improve knowledge around these topics. METHODS: The PREFER study is a prospective cohort study conducted across several Italian institution affiliated with the Gruppo Italiano Mammella (GIM) group evaluating patterns of care and clinical outcomes of young breast cancer patients dealing with fertility and pregnancy issues...
May 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28490170/fertility-preservation-for-social-and-oncofertility-indications
#15
Paul R Brezina
The desire to reproduce is a base human instinct. However, for many individuals, the chances of being able to have a genetic child are compromised by a number of factors. For some, therapies aimed at treating serious medical illness, such as cancer; result in a deleterious impact on the function of eggs and sperm in the future thus compromising future fertility. In women, a predictable decrease in egg quality and quantity occurs with advancing maternal age. Therefore, women who choose to delay childbearing until their late 30s or early 40s may experience fertility difficulties that would not have been present earlier in life...
May 8, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28468536/-oncofertility-and-therapeutic-modalities-survey-of-literature
#16
REVIEW
Tamás Sápy, Róbert Póka
Surgical and radiological treatment as well as chemotherapy and biological therapy may have harmful effects on young patients' future fertility. Increasingly greater emphasis has been put on ensuring these patients' long-term quality of life, therefore, in addition to survival, preserving their prospective fertility is also among our aims. The term 'oncofertility' has been compounded from two expressions, 'oncology' and attempts to 'fertility preservation'. In gynecology, fertility preservation involves not only special surgical procedures but also interventions intended to preserve gametes, reproductive organs and embryos...
May 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28463857/controversies-about-fertility-and-pregnancy-issues-in-young-breast-cancer-patients-current-state-of-the-art
#17
REVIEW
Matteo Lambertini, Oranite Goldrat, Florian Clatot, Isabelle Demeestere, Ahmad Awada
PURPOSE OF REVIEW: For trying to help physicians in counseling their young patients with breast cancer interested in fertility preservation and future reproductive plans, this manuscript aims to perform an overview of the main available data on 10 controversies in this field. RECENT FINDINGS: Thanks to the improvement in patients' prognosis, a growing attention towards fertility and pregnancy issues has been given over the past years and is currently provided to young breast cancer patients...
July 2017: Current Opinion in Oncology
https://www.readbyqxmd.com/read/28459598/practices-and-attitudes-regarding-women-undergoing-fertility-preservation-a-survey-of-the-national-physicians-cooperative
#18
Pietro Bortoletto, Rafael Confino, Brigid M Smith, Teresa K Woodruff, Mary Ellen Pavone
PURPOSE: To describe physician attitudes and variations in oncofertility treatment strategies. METHODS: An exploratory online survey administered between December 1, 2014 and January 27, 2015 to 185 members of the National Physicians Cooperative (NPC). RESULTS: Twenty-eight percent (52 of 185) of NPC members responded to the online survey. Fifty percent of respondents were obstetrician-gynecologists working largely in academic medical centers...
September 2017: Journal of Adolescent and Young Adult Oncology
https://www.readbyqxmd.com/read/28408620/oncofertility-fertile-ground-for-conflict-between-patient-autonomy-and-medical-values
#19
Sarah K Walsh, Elizabeth S Ginsburg, Lisa Soleymani Lehmann, Ann H Partridge
Oncofertility is a unique, multidisciplinary field that serves to bridge the gap between available fertility resources and the special reproductive needs of cancer patients. Oncofertility is a growing field due to the increasing number of survivors, development of new oncologic therapies, extension of duration of therapies, and development and refinement of reproductive therapies. While the technologies and demand for services expand, clinicians need to be appropriately prepared for dealing with various clinical scenarios that may require ethical deliberation...
July 2017: Oncologist
https://www.readbyqxmd.com/read/28333032/ethical-moral-and-other-aspects-related-to-fertility-preservation-in-cancer-patients
#20
Bruno Ramalho de Carvalho, Jhenifer Kliemchen, Teresa K Woodruff
Post-treatment fertility emerges as an important issue in the early counseling of individuals with cancer, since survivors may have their quality of life affected by the occurrence of functional failure of the gonads because of antineoplastic therapies. In the context, oncofertility has been developed as an interdisciplinary field of study that combines expertise in reproductive medicine and oncology, to provide strategies aiming to maintain the possibility of future procreation. Today, we have many options and techniques available for the preservation of gametes in men and women...
February 1, 2017: JBRA Assisted Reproduction
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