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Acute aortic injury

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https://www.readbyqxmd.com/read/28437243/impact-of-pulmonary-hypertension-on-in-hospital-outcome-after-surgical-or-transcatheter-aortic-valve-replacement
#1
Anja Gutmann, Klaus Kaier, Holger Reinecke, Lutz Frankenstein, Andreas Zirlik, Wolfgang Bothe, Constantin von Zur Mühlen, Manfred Zehender, Jochen Reinöhl, Christoph Bode, Peter Stachon
AIMS: The impact of pulmonary hypertension (PH) on in-hospital outcome of either surgical (SAVR) or transcatheter aortic valve replacement (TAVR) was analyzed. METHODS AND RESULTS: Data from all 107,057 patients undergoing isolated SAVR or TAVR in Germany between 2007 and 2014 was provided by the German Federal Bureau of Statistics. About 18% of patients with aortic valve stenosis suffered from PH. Patients with PH had more co- morbidities with consequently increased EuroSCORE (TAVR without PH: 12...
April 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28434554/the-simulation-based-assessment-of-pediatric-rapid-response-teams
#2
James J Fehr, Mary E McBride, John R Boulet, David J Murray
OBJECTIVE: To create scenarios of simulated decompensating pediatric patients to train pediatric rapid response teams (RRTs) and to determine whether the scenario scores provide a valid assessment of RRT performance with the hypothesis that RRTs led by intensivists-in-training would be better prepared to manage the scenarios than teams led by nurse practitioners. STUDY DESIGN: A set of 10 simulated scenarios was designed for the training and assessment of pediatric RRTs...
April 20, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28410995/transcatheter-versus-surgical-aortic-valve-replacement-in-patients-with-non-high-surgical-risk-severe-aortic-stenosis-a-systematic-review
#3
REVIEW
Tariq H Enezate, Arun Kumar, Mazen Abu Fadel, Mitul Patel, Ashraf Al Dadah, Jad Omran
OBJECTIVE: Transcatether aortic valve replacement (TAVR) has emerged as an acceptable alternative to surgical aortic valve replacement (SAVR) in patients with high-risk surgical profile. In this analysis, we compare both approaches in non-high surgical risk severe aortic stenosis. METHODS: Only studies comparing SAVR and TAVR and enrolling patients with low-intermediate risk were included from January 2000 through May 2016. Primary endpoints were assessed at 1 and 12months including: mortality, cerebrovascular accident (CVA) and myocardial infarction (MI)...
February 20, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28407819/-association-between-fluid-overload-and-acute-renal-injury-after-congenital-heart-disease-surgery-in-infants
#4
De-Qiang Luo, Zi-Li Chen, Wei Dai, Feng Chen
OBJECTIVE: To study the association between fluid overload and acute kidney injury (AKI) after congenital heart disease surgery in infants. METHODS: A retrospective analysis was performed on 88 infants aged less than 6 months who underwent a radical surgery for congenital heart disease. The treatment outcomes were compared between the infants with AKI after surgery and those without. The effect of cumulative fluid overload on treatment outcomes 2 days after surgery was analyzed...
April 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28400216/high-mortality-rates-after-both-open-surgical-and-endovascular-thoracic-aortic-interventions-in-patients-with-end-stage-renal-disease
#5
Nathan L Liang, Theodore H Yuo, Georges E Al-Khoury, Eric S Hager, Michel S Makaroun, Michael J Singh
BACKGROUND: Morbidity and mortality have improved with the evolution of endovascular techniques (thoracic endovascular aortic repair [TEVAR]) for thoracic aortic disease, but results after aortic intervention in patients with end-stage renal disease (ESRD) remain unclear. The objective of this study was to evaluate outcomes of open and endovascular descending thoracic aortic repair in dialysis-dependent patients. METHODS: We identified 352 patients with ESRD on dialysis undergoing open repair (n = 136) or TEVAR (n = 216) of the thoracic aorta from 2005 to 2008 using the United States Renal Data System database...
April 8, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28398671/transcatheter-versus-surgical-aortic-valve-replacement-in-intermediate-risk-patients-evidence-from-a-meta-analysis
#6
Partha Sardar, Amartya Kundu, Saurav Chatterjee, Dmitriy N Feldman, Theophilus Owan, Nikolaos Kakouros, Ramez Nairooz, Linda A Pape, Ted Feldman, J Dawn Abbott, Sammy Elmariah
OBJECTIVES: We performed a meta-analysis to evaluate the efficacy and safety of transcatheter aortic valve replacement (TAVR) in comparison to surgical aortic valve replacement (SAVR) in intermediate-risk patients. BACKGROUND: TAVR is an established treatment option in high-risk patients with severe aortic valve stenosis (AS). There are fewer data regarding efficacy of TAVR in intermediate-risk patients. METHODS: Databases were searched through April 30, 2016 for studies that compared TAVR with SAVR for the treatment of intermediate-risk patients with severe AS...
April 11, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28398399/-acute-aortic-dissection-during-ineffective-attempt-of-transcatheter-implant-of-a-fully-resheathable-respositionable-and-retrievable-aortic-valve
#7
Annamaria Dachille, Fortunato Iacovelli, Francesco Giardinelli, Emanuela De Cillis, Nicola Signore, Marco Matteo Ciccone, Stefano Favale, Gaetano Contegiacomo, Alessandro Santo Bortone
Aortic injury is a rare but severe complication that may occur during transcatheter aortic valve implantation (TAVI). Few patients with type A dissection are treated surgically because of the high rate of postoperative mortality and neurological complications in this high-risk population; thoracic endovascular aortic repair is rare too, and technically challenging because of the anatomical variations of spiral type A aortic dissection. Sometimes a watchful waiting strategy could be the best solution. We report the case of an acute, extended aortic type A dissection occurred during a TAVI procedure, probably due to the rupture of the dedicated sheath, and conservatively managed...
February 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/28395888/relation-of-intensity-of-statin-therapy-and-outcomes-after-transcatheter-aortic-valve-replacement
#8
Chetan P Huded, Lillian R Benck, Neil J Stone, Ranya N Sweis, Mark J Ricciardi, S Chris Malaisrie, Charles J Davidson, James D Flaherty
Statin therapy is associated with improved survival in patients at high risk for cardiovascular mortality, but the impact of statin therapy in patients treated with transcatheter aortic valve replacement (TAVR) is unknown. We reviewed 294 consecutive cases of TAVR performed at a single tertiary care medical center. We defined high-intensity statin therapy as atorvastatin 40 to 80 mg/day or rosuvastatin 20 to 40 mg/day. Study outcomes included post-TAVR adverse events, 30-day mortality, and overall survival...
March 16, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28395872/outcomes-of-antegrade-stent-graft-deployment-during-hybrid-aortic-arch-repair
#9
Seyed Hossein Aalaei-Andabili, Salvatore Scali, Charles Klodell, Teng Lee, Philip Hess, Tomas Martin, Adam Beck, Robert Feezor, Mahmoud Alhussaini, George Arnaoutakis, Thomas Beaver
BACKGROUND: Complex aortic arch disease can be a formidable challenge and is often treated with a two-stage elephant trunk technique. We examined our experience with hybrid arch repair with combined zone 0 stent graft deployment. METHODS: A retrospective review was conducted of all patients who underwent type 2 hybrid arch replacement and zone 0 antegrade endovascular stent graft deployments at a single university center from June 2010 to August 2015. RESULTS: The review included 48 patients, 25 (52%) elective and 23 (48%) nonelective, with a mean ± SD age of 64 ± 11 years...
April 7, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28389290/symptomatic-intragraft-thrombus-following-endovascular-repair-of-blunt-thoracic-aortic-injury
#10
Sherwin Abdoli, Sung Wan Ham, Alison G Wilcox, Fernando Fleischman, Lydia Lam
INTRODUCTION: Thoracic endovascular aortic repair (TEVAR) can be complicated by graft collapse, endoleaks, and stent migration. The incidence of these complications and other outcomes is poorly understood in young trauma victims who receive endovascular aortic repair of blunt thoracic aortic injury. REPORT: A 29 year-old pedestrian was struck by a vehicle resulting in polytrauma including blunt thoracic aortic injury (BTAI) with transection distal to the left subclavian artery origin...
April 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28389283/the-protective-effect-of-curcumin-on-a-spinal-cord-ischemia-reperfusion-injury-model
#11
İlker Akar, İlker İnce, Akgül Arici, İsmail Benli, Cemal Aslan, Sefa Şenol, Osman Demir, Fatih Altunkas, Nuray Altındeger, Ali Akbas
BACKGROUND: The purpose of this study is to investigate the neurological, biochemical, and histopathologic effects of both the acute and maintenance treatment of curcumin on an experimental spinal cord ischemia-reperfusion injury model in rats. MATERIAL AND METHODS: The animals were randomly divided into 4 groups: 1. Sham, 2. Ischemia-reperfusion (IR), 3. Curcumin, and 4. Solvent. Spinal cord ischemia was induced by clamping the aorta with minivascular clamps at a position just below the left renal artery and just proximal to the aortic bifurcation for 45 min...
April 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28387896/expression-of-profilin-1-in-endothelial-cells-of-rats-with-acute-myocardial-infarction
#12
P Hao, K Fu, S-P Wang, C-Y Ma, Z-Y Xu, F-Y Cao, J-H Liu
OBJECTIVE: To analyze the expression of profilin-1 in endothelial cells of rats with acute myocardial infarction. MATERIALS AND METHODS: Twenty adult male Wistar rats were randomly divided into the myocardial infarction (model) group (n=10) and sham-operation (control) group (n=10). The expression of profilin-1 and phosphorylated extracellular signal kinase (pERK1/2) in aortic endothelial cells, indexes of endothelial injury [levels of endothelial microparticles (EMPs) and nitric oxide (NO)], indexes of myocardial injury [cardiac troponin T (cTnT) and creatine kinase-MB (CK-MB)], and mRNA levels of myocardial apoptotic factors (P53, Fas, Bax, and Bcl-2) in rats between the two groups were compared...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28385646/independent-risk-factors-contributing-to-acute-kidney-injury-according-to-updated-valve-academic-research-consortium-2-criteria-after-transcatheter-aortic-valve-implantation-a-meta-analysis-and-meta-regression-of-13-studies
#13
Jiayang Wang, Wenyuan Yu, Ye Zhou, Yong Yang, Chenglong Li, Nan Liu, Xiaotong Hou, Longfei Wang
OBJECTIVES: This study aimed to examine the risk factors for transcatheter aortic valve implantation (TAVI)-associated acute kidney injury (AKI) according to the AKI definition from the Valve Academic Research Consortium-2 (VARC-2). SETTING: A meta-analysis. PARTICIPANTS: A total of 661 patients with post-TAVI AKI according to the VARC-2 definition and 2,012 controls were included in the meta-analysis. INTERVENTIONS: Patients undergoing TAVI were included in this meta-analysis...
December 21, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28382803/impact-of-previous-cardiac-surgery-in-patients-undergoing-transcatheter-aortic-valve-implantation-a-systematic-review
#14
Sharaf-Eldin Shehada, Yacine Elhmidi, Nazan Puluca, Öznur Öztürk, Ender Demircioglu, Daniel Wendt, Heinz Jakob, Matthias Thielmann
INTRODUCTION: Redo surgical aortic valve replacement after prior cardiac surgery is usually related to a higher risk of mortality and morbidity. Transcatheter aortic valve implantation (TAVI) became an alternative therapy for those patients in the past couple of years. EVIDENCE ACQUISITION: We aimed in this study to analyze the outcomes of patients undergoing TAVI after a prior cardiac surgery especially those who underwent coronary artery bypass grafting (CABG) and to see if TAVI offers any advantages for those patients than conventional surgical aortic valve replacement...
April 4, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28369452/management-of-cerebral-malperfusion-in-surgical-repair-of-acute-type-a-aortic-dissection
#15
Tomokuni Furukawa, Naomichi Uchida, Shinya Takahashi, Yoshitaka Yamane, Shingo Mochizuki, Kazunori Yamada, Takaaki Mochizuki, Taijiro Sueda
OBJECTIVES: Cerebral malperfusion for patients with acute type A aortic dissection (AAAD) remains an unsolved problem. The present study aimed to evaluate our management of cerebral perfusion and identify predictors of perioperative cerebral malperfusion in patients undergoing surgical repair of AAAD. METHODS: Between January 2004 and December 2015, 137 consecutive patients with AAAD underwent aortic replacement at Tsuchiya General Hospital. The status of the dissected supra-aortic branch vessels (SABVs) was classified as patent or thrombosis by preoperative computed tomographic angiography...
March 20, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28364444/acute-type-a-dissection-in-octogenarians-does-emergency-surgery-impact-in-hospital-outcome-or-long-term-survival-%C3%A2
#16
Julia Dumfarth, Sven Peterss, Maximilian Luehr, Christian D Etz, Thomas Schachner, Markus Kofler, Bulat A Ziganshin, Hanno Ulmer, Michael Grimm, John A Elefteriades, Friedrich W Mohr
OBJECTIVES: Surgical therapy for acute aortic dissection type A (AADA) in octogenarians carries high morbidity and mortality. The role of isolated medical treatment in this setting is controversial. The aim of this study is to determine whether risk of surgery for AADA outweighs risk of death from medical treatment only. METHODS: From 2002 to 2015, 90 consecutive octogenarians (mean age, 83.5 ± 3 years) were treated for AADA at three institutions: 67 patients underwent surgery, 23 patients received medical treatment...
March 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28359795/estimation-of-v-possum-and-e-pass-scores-in-prediction-of-acute-kidney-injury-in-patients-after-elective-open-abdominal-aortic-aneurysm-surgery
#17
Andrzej Siemiatkowski, Agnieszka Jablonowska, Joanna Pietrewicz, Jerzy Glowinski
BACKGROUND: V-POSSUM and E-PASS scoring systems are usually used to predict morbidity and early mortality in surgical patients. We conducted this study to assess the validity of the V-POSSUM and E-PASS scores in predicting risk of acute kidney injury (AKI) development in patients undergoing elective open abdominal aortic aneurysm (AAA) repair. METHODS: We studied a consecutive series of 171 patients with AAA, qualified for elective open infrarenal repair. Patients underwent a thorough examination and the physiological and surgical stress components of the V-POSSUM and E-PASS scores were calculated...
March 27, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28355771/-progress-of-problems-related-to-the-reconstruction-of-aortic-arch-in-acute-type-a-aortic-dissection
#18
N N Liu, L Z Sun
Aortic arch reconstruction is one of the most challenging operations in aortic surgery. Anatomical abnormalities of the aortic arch, including bovine aortic arch, aberrant right subclavian artery, and single vertebral artery have direct impact on the choice of surgical procedures and methods of brain protection.The risk of aortic arch reconstruction and the difficulty of operation, it is possible to avoid the injury of patients by strictly grasping the indication of operation. Intraoperative arterial cannulation and brain protection strategies are directly related to the success of the operation...
April 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28355764/-prognostic-factors-for-in-hospital-mortality-in-patients-with-acute-kidney-injury-requiring-continuous-renal-replacement-therapy-undergoing-surgery-for-acute-stanford-type-a-aortic-dissection
#19
R Jiao, N Liu
Objective: To evaluate prognostic factors for in-hospital mortality in patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) undergoing surgery for acute Stanford type A aortic dissection. Methods: Retrospective analysis were conducted for 60 patients diagnosed with AKI requiring CRRT undergoing surgery for acute Stanford type A aortic dissection at Beijing Anzhen Hospital, Capital Medical University from March 2015 to September 2016. There were 43 male and 17 female patients with an mean age of (50±14) years...
April 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28342840/the-ratio-of-contrast-volume-to-glomerular-filtration-rate-predicts-acute-kidney-injury-and-mortality-after-transcatheter-aortic-valve-implantation
#20
Francesco Giannini, Azeem Latib, Richard J Jabbour, Massimo Slavich, Susanna Benincasa, Alaide Chieffo, Matteo Montorfano, Stefano Stella, Nicola Buzzatti, Ottavio Alfieri, Antonio Colombo
OBJECTIVE: The aim of this study was to assess the impact of the ratio of volume of contrast medium to the glomerular filtration rate (V/GFR) on acute kidney injury (AKI) after transcatheter aortic valve implantation (TAVI) and its impact on long-term mortality. METHODS: We retrospectively calculated V/GFR in 397 patients undergoing TAVI. AKI was defined as VARC-modified Risk, Injury, Failure, Loss and End-stage (RIFLE) kidney disease score≥2. RESULTS: The incidence of AKI was 17...
February 20, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
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