Qingfei Chen, Qifei Deng, Qilong Liao, Yan Liu, Zhaorui Zhang, Dehua Wu, Yanrong Lv, Jingyao Qin, Qing Liu, Shuangqi Li, Zihao Long, Xiumei Xing, Qing Wang, Xiaowen Zeng, Guanghui Dong, Mengjun Hou, Yongmei Xiao
Individual typical endocrine-disrupting chemicals (EDCs), including organophosphate triesters (OPEs), parabens, triclosan (TCS), bisphenols, benzophenones (BPs), phthalates (PAEs), and synthetic phenolic antioxidants (SPAs), are associated with renal dysfunction. However, the combined effects and underlying mechanisms of mixed EDC exposure on renal function remain unclear. Two hundred ninety-nine adult participants were enrolled in the cross-sectional survey conducted in Guangzhou, China. Urinary levels of 7 OPEs, 6 parabens, TCS, 14 bisphenols, 8 BPs, 15 PAEs, 4 SPAs, and 8-hydroxy-2'-deoxyguanosine (8-OHdG) were determined, and estimated glomerular filtration rate (eGFR) was served as the outcome index...
April 13, 2024: Environmental Science and Pollution Research International