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Triclosan

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https://www.readbyqxmd.com/read/29772265/administration-of-low-dose-triclosan-to-pregnant-ewes-results-in-placental-uptake-and-reduced-estradiol-sulfotransferase-activity-in-fetal-liver-and-placenta
#1
Erin N Jackson, Laura Rowland-Faux, Margaret O James, Charles E Wood
Sulfonation is a major pathway of estrogen biotransformation with a role in regulating estrogen homeostasis in humans and sheep. Previous in vitro studies found that triclosan is an especially potent competitive inhibitor of ovine placental estrogen sulfotransferase, with Kic of <0.1 nM. As the placenta is the main organ responsible for estrogen synthesis in pregnancy in both women and sheep, and the liver is another site of estrogen biotransformation, this study examined the effects of triclosan exposure of pregnant ewes on placental and hepatic sulfotransferase activity...
May 14, 2018: Toxicology Letters
https://www.readbyqxmd.com/read/29757174/magnetic-solid-phase-extraction-for-the-analysis-of-bisphenol-a-naproxen-and-triclosan-in-wastewater-samples
#2
Guo Li, Ruoyu Deng, Guilong Peng, Chun Yang, Qiang He, Ying Lu, Huilan Shi
Magnetic Fe3 O4 graphene oxide nanocomposite was synthesized by chemical coprecipitation method and characterized by scanning electron microscopy, Fourier transform infrared spectra and X-ray diffraction. A simple, rapid, convenient and environmentally friendly method was developed for separation and pre-concentration of trace amounts of bisphenol A, naproxen and triclosan in wastewater samples by high performance liquid chromatography with magnetic Fe3 O4 graphene oxide nanocomposite as the adsorbent for magnetic solid-phase extraction...
May 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29757172/spectrophotometric-determination-of-triclosan-based-on-diazotization-reaction-response-surface-optimization-using-box-behnken-design
#3
Inderpreet Kaur, Sonal Gaba, Sukhraj Kaur, Rajeev Kumar, Jyoti Chawla
A spectrophotometric method based on diazotization of aniline with triclosan has been developed for the determination of triclosan in water samples. The diazotization process involves two steps: (1) reaction of aniline with sodium nitrite in an acidic medium to form diazonium ion and (2) reaction of diazonium ion with triclosan to form a yellowish-orange azo compound in an alkaline medium. The resulting yellowish-orange product has a maximum absorption at 352 nm which allows the determination of triclosan in aqueous solution in the linear concentration range of 0...
May 2018: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/29754027/urinary-concentrations-of-phthalate-metabolites-bisphenols-and-personal-care-product-chemical-biomarkers-in-pregnant-women-in-israel
#4
Ronit Machtinger, Tamar Berman, Michal Adir, Abdallah Mansur, Andrea A Baccarelli, Catherine Racowsky, Antonia M Calafat, Russ Hauser, Ravit Nahum
Mounting evidence suggests possible adverse effects of intrauterine exposure to certain phenols and phthalates, two classes of endocrine disruptor chemicals, on the developing fetus, with consequences into later life. These findings have contributed to the replacement of some chemicals, such as di‑2‑ethylhexyl phthalate (DEHP) and bisphenol A (BPA), in consumer products. For the current study we quantified urinary concentrations of biomarkers of exposure among 50 pregnant women in Israel to several phthalates, bisphenols and personal care product chemicals, as well as DEHP and BPA alternatives...
May 10, 2018: Environment International
https://www.readbyqxmd.com/read/29751307/systematic-screening-and-identification-of-the-chlorinated-transformation-products-of-aromatic-pharmaceuticals-and-personal-care-products-using-high-resolution-mass-spectrometry
#5
Wen-Ling Chen, Jiun-Yi Cheng, Xiao-Qian Lin
Pharmaceuticals and personal care products (PPCPs) are an emerging concern because of the large amount of PPCPs that is discharged and its potential ecological effects on the aquatic environment. Chlorination has proven efficient for removing some aromatic PPCPs from wastewater, but the formation of by-products has not been thoroughly investigated partly because of analytical difficulties. This study developed a method for systematically screening and identifying the transformation products (TPs) of multiple aromatic PPCPs through high-resolution mass spectrometry (HRMS)...
May 8, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29748801/nanocomposite-au-np-tio-2-thin-film-in-the-efficient-remediation-of-aqueous-solutions-contaminated-with-emerging-micro-pollutants
#6
Lalliansanga Nil, Alka Tiwari, Alok Shukla, Diwakar Tiwari, Seung Mok Lee
The present communication specifically aims to synthesize novel nanocomposite material Au NPs/TiO2 in a simple template process using the polyethylene glycol as filler media. The thin film of the nanocomposite material was characterized by the advanced analytical tools. The surface morphology was obtained by the scanning electron microscopic (SEM) and transmission electron microscopic (TEM) images of solids. Similarly, the surface topography and roughness of solid were obtained by the atomic force microscopic (AFM) image of thin film...
May 10, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29732474/degradation-of-triclosan-by-environmental-microbial-consortia-and-by-axenic-cultures-of-microorganisms-with-concerns-to-wastewater-treatment
#7
REVIEW
Xijuan Chen, Jie Zhuang, Kai Bester
Triclosan is an antimicrobial agent, which is widely used in personal care products including toothpaste, soaps, deodorants, plastics, and cosmetics. Widespread use of triclosan has resulted in its release into wastewater, surface water, and soils and has received considerable attention in the recent years. It has been reported that triclosan is detected in various environmental compartments. Toxicity studies have suggested its potential environmental impacts, especially to aquatic ecosystems. To date, removal of triclosan has attracted rising attention and biodegradation of triclosan in different systems, such as axenic cultures of microorganisms, full-scale WWTPs, activated sludge, sludge treatment systems, sludge-amended soils, and sediments has been described...
May 7, 2018: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29728280/intensification-of-uv-c-tertiary-treatment-disinfection-and-removal-of-micropollutants-by-sulfate-radical-based-advanced-oxidation-processes
#8
J Rodríguez-Chueca, C García-Cañibano, R-J Lepistö, Á Encinas, J Pellinen, J Marugán
This study explores the enhancement of UV-C tertiary treatment by sulfate radical based Advanced Oxidation Processes (SR-AOPs), including photolytic activation of peroxymonosulfate (PMS) and persulfate (PS) and their photocatalytic activation using Fe(II). Their efficiency was assessed both for the inactivation of microorganisms and the removal or micropollutants (MPs) in real wastewater treatment plant effluents. Under the studied experimental range (UV-C dose 5.7-57 J/L; UV-C contact time 3 to 28 s), the photolysis of PMS and PS (0...
April 21, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29727133/identifying-vulnerable-periods-of-neurotoxicity-to-triclosan-exposure-in-children
#9
Medina S Jackson-Browne, George D Papandonatos, Aimin Chen, Antonia M Calafat, Kimberly Yolton, Bruce P Lanphear, Joseph M Braun
BACKGROUND: Exposure to triclosan, an endocrine disrupting chemical, may affect thyroid hormone homeostasis and adversely affect neurodevelopment. OBJECTIVE: Using a longitudinal pregnancy and birth cohort, we investigated associations between triclosan exposures during different time windows, and cognitive test scores at 8 y of age in 198 children from the HOME Study. METHODS: We quantified triclosan in urine samples from mother-child pairs up to nine times between the second trimester of gestation and 8 y of age...
May 2, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29725723/occurrence-and-ecological-risk-assessment-of-eight-endocrine-disrupting-chemicals-in-urban-river-water-and-sediments-of-south-china
#10
Cong Huang, Liu-Hong Wu, Guo-Qiang Liu, Lei Shi, Ying Guo
Chemicals in the water of urban areas are representative of the occurrence of these chemicals in the city surrounding water systems and reflect recent human or industrial usage of those chemicals in the sampling areas. In this study, the levels of eight endocrine-disrupting chemicals [including bisphenol analogues, parabens, and triclosan (TCS)] were determined in urban river water and sediments in Guangzhou, South China, and their related ecological risks were evaluated. The eight target chemicals were frequently detected in our samples, with concentrations ranging from not detected (ND) to 65,600 ng/L and from ND to 492 ng/g dw in river water and sediments, respectively...
May 3, 2018: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29722443/biomonitoring-of-bisphenol-a-triclosan-and-perfluorooctanoic-acid-in-hair-samples-of-children-and-adults
#11
Vasiliki Karzi, Manolis N Tzatzarakis, Elena Vakonaki, Thanasis Alegakis, Ioanna Katsikantami, Stavros Sifakis, Apostolos Rizos, Aristidis M Tsatsakis
Bisphenol A (BPA), triclosan (TCS) and perfluorooctanoic acid (PFOA) are endocrine disruptors linked with negative health effects such as developmental, reproductive and cardiovascular toxicity. The aim of this study was to determine simultaneously the concentration of BPA, TCS and PFOA in hair from children and adults and examine possible associations between biomonitoring data and age, gender, dietary habits and body mass index. Methanolic extraction was applied and the compounds were determined by liquid chromatography-mass spectrometry...
May 3, 2018: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/29721219/-in-vitro-quantitative-comparison-of-erosive-potential-of-infant-mouthwashes-on-glass-ionomer-cement
#12
Aline-Bastos da Silva, Nayre-Maria-Lauande Rapôso, Isabella-Azevedo Gomes, Letícia-Machado Gonçalves, Marco-Aurélio-Benini Paschoal
Background: The widespread use of mouthwashes, specially in children, is a concern, since the long-term use may modify the topography of dental materials. However, this process still unclear regarding the wear related to infant mouthwashes on glass ionomer cement. Thus, the purpose of this investigation was evaluate the erosive potential of infant mouthwashes on glass ionomer cement specimens. Material and Methods: Forty round-shaped specimens were divided into 4 groups (N=10) and submitted to erosive cycling for 15 days, being exposed 2X/day in the following children's active agents mouthwash solutions: G1- cetylpyridinium chloride, G2- xylitol and triclosan and G3 - Malva sylvestris and xylitol...
March 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29717430/biochemical-and-life-cycle-effects-of-triclosan-chronic-toxicity-to-earthworm-eisenia-fetida
#13
Jurate Zaltauskaite, Diana Miskelyte
The study aimed at determining the response of adult Eisenia fetida earthworms to chronic exposure to triclosan (TCS) (10-750 mg kg-1 ) in soil. TCS life cycle toxicity was evaluated by the means of survival, growth rate, and reproduction assessment. Biochemical responses including changes in the activity of antioxidative enzymes (catalase, superoxide dismutase, and glutathione reductase) and concentration of malondialdehyde (MDA) were determined. Significant reduction in the earthworm survival was observed only if the exposure to TCS was longer than 4 weeks...
May 2, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29716562/heavy-ion-mutagenesis-combined-with-triclosan-screening-provides-a-new-strategy-for-improving-the-arachidonic-acid-yield-in-mortierella-alpina
#14
Huidan Zhang, Dong Lu, Xin Li, Yingang Feng, Qiu Cui, Xiaojin Song
BACKGROUND: Arachidonic acid (ARA), which is a ω-6 polyunsaturated fatty acid, has a wide range of biological activities and is an essential component of cellular membranes in some human tissues. Mortierella alpina is the best strain for industrial production of ARA. To increase its yield of arachidonic acid, heavy ion beam irradiation mutagenesis of Mortierella alpina was carried out in combination with triclosan and octyl gallate treatment. RESULTS: The obtained mutant strain F-23 ultimately achieved an ARA yield of 5...
May 2, 2018: BMC Biotechnology
https://www.readbyqxmd.com/read/29710583/survey-of-selected-personal-care-products-in-surface-water-of-coral-reefs-in-kenting-national-park-taiwan
#15
Te An Kung, Shu Hui Lee, Ting Chi Yang, Wei Hsien Wang
Kenting National Park (KNP) located in the Hengchun Peninsula in southern Taiwan is a popular tourist spot, annually attracting millions of visitors, who engage in water sport and amusement activities. In this region, sewage is directly discharged into the marine environment. In this study, the concentrations of five organic UV filters [benzophenone (BP), 2,4-dihydroxy benzophenone (BP-1), 2-hydroxy-4-methoxy benzophenone (BP-3), 2,2'-dihydroxy-4-methoxy benzophenone (BP-8), and 4-methylbenzylidene camphor], five preservatives [methylparaben (MeP), ethylparaben, propylparaben (PrP), butylparaben, and benzylparaben], one disinfectant [triclosan (TCS)], and twenty-four detergent derivatives [nonylphenol (NP), nonylphenol ethoxylates (NP2EO-NP12EO), octylphenol (OP) and octylphenol ethoxylates OP2EO-OP12EO] were detected in seawater and river water samples collected from eight beaches in KNP and two major river estuaries in the Hengchun Peninsula...
April 23, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29710573/the-application-of-gac-sandwich-slow-sand-filtration-to-remove-pharmaceutical-and-personal-care-products
#16
Jianan Li, Qizhi Zhou, Luiza C Campos
Lab-scale GAC sandwich slow sand filters with different GAC layer depths were evaluated for the first time to remove selected pharmaceutical and personal care products (PPCPs) (namely DEET, paracetamol, caffeine and triclosan, 25 μg/L). Coarse sand (effective grain size of 0.6 mm) was used instead of conventional fine sand. In addition to single sand and GAC filters, GAC sandwich filters were assessed at three filtration rates (i.e. 5 cm/h, 10 cm/h and 20 cm/h) to compare removals. Sandwich filter with 20 cm GAC achieved the best average PPCP removal (98...
April 22, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29709864/identification-contribution-and-estrogenic-activity-of-potential-edcs-in-a-river-receiving-concentrated-livestock-effluent-in-southern-taiwan
#17
Yung-Yu Liu, Yi-Siou Lin, Chia-Hung Yen, Chang-Ling Miaw, Ting-Chien Chen, Meng-Chun Wu, Chi-Ying Hsieh
We assessed 22 selected endocrine-disrupting compounds (EDCs) and other emerging, potentially endocrine-active compounds with estrogenic activity from the waters of the Wuluo River, southern Taiwan. This watershed receives high amounts of livestock and untreated household wastewaters. The river is surrounded by concentrated animal feedlot operations (CAFOs). River water samples were analyzed for selected compounds by liquid chromatography-tandem mass spectrometry (LC-MS/MS), T47D-KBluc reporter gene assay, and E-screen cell proliferation in vitro bioassay...
April 27, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29704805/advanced-data-mining-approaches-in-the-assessment-of-urinary-concentrations-of-bisphenols-chlorophenols-parabens-and-benzophenones-in-brazilian-children-and-their-association-to-dna-damage
#18
Bruno A Rocha, Alexandros G Asimakopoulos, Masato Honda, Nattane L da Costa, Rommel M Barbosa, Fernando Barbosa, Kurunthachalam Kannan
Human exposure to endocrine disrupting chemicals (EDCs) has received considerable attention over the last three decades. However, little is known about the influence of co-exposure to multiple EDCs on effect-biomarkers such as oxidative stress in Brazilian children. In this study, concentrations of 40 EDCs were determined in urine samples collected from 300 Brazilian children of ages 6-14 years and data were analyzed by advanced data mining techniques. Oxidative DNA damage was evaluated from the urinary concentrations of 8-hydroxy-2'-deoxyguanosine (8OHDG)...
April 25, 2018: Environment International
https://www.readbyqxmd.com/read/29690855/maternal-phthalate-and-personal-care-products-exposure-alters-extracellular-placental-mirna-profile-in-twin-pregnancies
#19
Jia Zhong, Andrea A Baccarelli, Abdallah Mansur, Michal Adir, Ravit Nahum, Russ Hauser, Valentina Bollati, Catherine Racowsky, Ronit Machtinger
Prenatal exposure to endocrine-disrupting chemicals (EDCs) exerts both short- and long-term adverse effects on the developing fetus. However, the mechanisms underlying these effects have yet to be uncovered. Maternal-fetal signaling is mediated in part by signaling molecules (eg, microRNAs [miRNAs]) contained in extracellular vesicles (EVs) that are released by the placenta into the maternal circulation. We investigated whether maternal exposure to the EDCs phthalates and personal care products alters the miRNA profile of placental-derived EVs circulating in maternal blood...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29689407/immobilization-of-triclosan-and-erythrosine-in-layer-by-layer-films-applied-to-inactivation-of-microorganisms
#20
Maria F Costa Pedro, Alessandro S Kalck, Kevin F Dos Santos, Marcos S Sousa, Karla B Romio, Paula C S Souto, Josmary R Silva, Nara C de Souza
The use of the layer-by-layer (LbL) deposition technique allows materials, such as drugs, to be self-assembled in multilayers with other electrolytes by combining their properties in a nanostructured system. Triclosan (TCS) is commonly used as a drug because of its bactericidal action, while erythrosine (ERY) has been used as a photosensitizer in photodynamic therapies because of its high light absorptivity in the visible region of the electromagnetic spectrum. The major advantage of investigating systems immobilized in LbL films is the benefit of characterizing the interaction through available substances in solid state techniques...
April 21, 2018: Photodiagnosis and Photodynamic Therapy
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