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https://www.readbyqxmd.com/read/28213709/high-efficiency-removal-of-triclosan-by-structure-directing-agent-modified-mesoporous-mil-53-al
#1
Rongni Dou, Junya Zhang, Yuancai Chen, Siyuan Feng
In order to expand the potential applications of metal-organic frameworks (MOFs), structure directing agents modified mesoporous MIL-53(Al) (MIL-53(Al)-1) was investigated to adsorb triclosan (TCS) with two different initial concentrations. MIL-53(Al)-1 with high mesoporosity and total pore volume exhibited higher adsorption capacity and 4.4 times faster adsorption of TCS at low concentration (1 mg L(-1)) than that of microporous MIL-53(Al). Also, mesoporous as well as microporous MIL-53(Al) showed significant higher adsorption capacity and two orders of magnitude greater fast uptake of TCS than two kinds of mesoporous-activated carbon...
February 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28203426/a-novel-technique-for-chest-drain-removal-using-a-two-layer-method-with-triclosan-coated-sutures
#2
Yujiro Yokoyama, Takahiro Nakagomi, Daichi Shikata, Taichiro Goto
In thoracic surgery, a thoracic drain is always inserted after the surgical procedure. Repair of the wound after removal of the thoracic tube is performed postoperatively, but no universally standard methods currently exists for this tube removal. Here we report a technique using triclosan-coated sutures that is used in thoracic surgery in our hospital. There are several advantages of this technique. First, there is no need for stitches removal on follow-up. Second, it prevents the leakage of pleural exudate because of the tight two-layer sutures...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28198617/cometabolic-enzymatic-transformation-of-organic-micropollutants-under-methanogenic-conditions
#3
Lorena Gonzalez-Gil, Marta Carballa, Juan M Lema
Anaerobic digestion (AD) has been shown to have the biological potential to decrease the concentrations of several organic micropollutants (OMPs) from sewage sludge. However, the mechanisms and factors behind these biotransformations, which are essential for elucidating the possible transformation products and to foster the complete removal of OMPs via operational strategies, remain unclear. Therefore, this study investigated the transformation mechanisms of 20 OMPs during the methanogenic step of AD with a focus on the role of acetate kinase (AK), which is a key enzyme in methane production...
February 15, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28193654/clinical-relevance-of-fasii-bypass-in-staphylococcus-aureus
#4
Karine Gloux, Mélanie Guillemet, Charles Soler, Claire Morvan, David Halpern, Christine Pourcel, Hoang Vu Thien, Gilles Lamberet, Alexandra Gruss
The need for new antimicrobials to treat bacterial infections has led to the use of fatty acid synthesis (FASII) enzymes as front-line targets. However, recent studies suggest that FASII inhibitors may not work against the opportunist pathogen Staphylococcus aureus, as environmental fatty acids favor emergence of multi-anti-FASII resistance. As fatty acids are abundant in the host, and one FASII inhibitor, triclosan, is widespread, we investigated whether fatty acid pools impact resistance in clinical and veterinary S...
February 13, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28191571/a-computer-based-prediction-platform-for-the-reaction-of-ozone-with-organic-compounds-in-aqueous-solution-kinetics-and-mechanisms
#5
Minju Lee, Lorenz C Blum, Emanuel Schmid, Kathrin Fenner, Urs von Gunten
Ozonation of secondary wastewater effluents can reduce the discharge of micropollutants by transforming their chemical structures. Therefore, a better understanding of the formation of transformation products during ozonation is important. In this study, a computer-based prediction platform for the kinetics and mechanisms of the reactions of ozone with organic compounds was developed to enable in silico predictions of transformation products. With the developed prediction platform, reaction kinetics expressed as second-order rate constants for the reactions of ozone with selected organic compounds (kO3, M(-1) s(-1)) can be predicted based on an adapted kO3 prediction model from a previous study (Lee et al...
February 13, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28169850/american-contact-dermatitis-society-core-allergen-series-2017-update
#6
Peter C Schalock, Cory A Dunnick, Susan Nedorost, Bruce Brod, Erin Warshaw, Christen Mowad
The American Contact Dermatitis Society Core Allergen Series was introduced in 2012. After 4 years of use, changes in our recommended allergens are necessary. For the updated series, we have reordered the first 4 panels to approximately mirror the current TRUE Test and removed parthenolide, triclosan, glutaraldehyde, and jasmine. Polymyxin B, lavender, sodium benzoate, ethylhexylglycerin, and benzoic acid are new additions to the American Contact Dermatitis Society series.
February 6, 2017: Dermatitis
https://www.readbyqxmd.com/read/28150092/antimicrobial-activity-study-of-triclosan-loaded-wbpu-on-proteus-mirabilis-in-vitro
#7
Ye Tian, Zhongyu Jian, Jianzhong Wang, Wei He, Qinyu Liu, Kunjie Wang, Hong Li, Hong Tan
OBJECTIVES: To evaluate the antimicrobial activity study of triclosan-loaded waterborne polyurethanes (WBPU) on Proteus mirabilis in vitro. MATERIALS AND METHODS: Inhibition zone assays on petri plates with triclosan-loaded WBPU samples were used to test its antimicrobial activity on Proteus mirabilis. Models of the catheterized bladder supplied with artificial urine infected with Proteus mirabilis were employed to confirm the antimicrobial activity of triclosan-loaded WBPU...
February 1, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28132117/evaluation-of-antimicrobial-persistent-activity-of-alcohol-based-hand-antiseptics-against-bacterial-contamination
#8
R M López-Gigosos, E Mariscal-López, M Gutierrez-Bedmar, A García-Rodriguez, A Mariscal
The purpose of this study was to evaluate persistent activity of three alcohol-based antiseptics widely used in the clinical routine containing chlorhexidine, triclosan or mecetronium after hand disinfection. Four tests were used to evaluate the antimicrobial activity of antiseptics on: (i) resident microbiota; (ii) nutrient agar plates (NAP) subsequently inoculated with a test organism; and transient microbiota acquired by contact with dry hands (iii), or (iv) a wet inert surface that had been artificially contaminated...
January 28, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28128979/studies-of-staphylococcus-aureus-fabi-inhibitors-fragment-based-approach-based-on-holographic-structure-activity-relationship-analyses
#9
Thales Kronenberger, Leonardo Rander Asse, Carsten Wrenger, Gustavo Henrique Goulart Trossini, Kathia Maria Honorio, Vinicius Gonçalves Maltarollo
AIM: FabI is a key enzyme in the fatty acid metabolism of Gram-positive bacteria such as Staphylococcus aureus and is an established drug target for known antibiotics such as triclosan. However, due to increasing antibacterial resistance, there is an urgent demand for new drug discovery. Recently, aminopyridine derivatives have been proposed as promising competitive inhibitors of FabI. METHODS: In the present study, holographic structure-activity relationship (HQSAR) analyses were employed for determining structural contributions of a series containing 105 FabI inhibitors...
January 2017: Future Medicinal Chemistry
https://www.readbyqxmd.com/read/28128024/studies-of-staphylococcus-aureus-fabi-inhibitors-fragment-based-approach-based-on-holographic-structure-activity-relationship-analyses
#10
Thales Kronenberger, Leonardo Rander Asse, Carsten Wrenger, Gustavo Henrique Goulart Trossini, Kathia Maria Honorio, Vinicius Gonçalves Maltarollo
AIM: FabI is a key enzyme in the fatty acid metabolism of Gram-positive bacteria such as Staphylococcus aureus and is an established drug target for known antibiotics such as triclosan. However, due to increasing antibacterial resistance, there is an urgent demand for new drug discovery. Recently, aminopyridine derivatives have been proposed as promising competitive inhibitors of FabI. METHODS: In the present study, holographic structure-activity relationship (HQSAR) analyses were employed for determining structural contributions of a series containing 105 FabI inhibitors...
January 27, 2017: Future Medicinal Chemistry
https://www.readbyqxmd.com/read/28128023/hypothesis-driven-weight-of-evidence-analysis-of-endocrine-disruption-potential-a-case-study-with-triclosan
#11
Ellen Mihaich, Marie Capdevielle, Daniella Urbach-Ross, Brian Slezak
Triclosan is an antimicrobial agent used in a range of consumer products, such as deodorants, oral care, clothing, and household items. As with many consumer products, triclosan can be rinsed down the drain and transported to wastewater treatment plants. While most is eliminated during activated sludge sewage treatment by biodegradation and adsorption, some triclosan enters the aquatic environment and may expose wildlife. Given the potential for exposure to both humans and wildlife, resolving whether triclosan is endocrine active is important due to growing concerns about potential adverse public health and environmental effects of endocrine-disrupting substances...
January 27, 2017: Critical Reviews in Toxicology
https://www.readbyqxmd.com/read/28121465/topical-application-of-the-anti-microbial-chemical-triclosan-induces-immunomodulatory-responses-through-the-s100a8-a9-tlr4-pathway
#12
Nikki B Marshall, Ewa Lukomska, Ajay P Nayak, Carrie M Long, Justin M Hettick, Stacey E Anderson
The anti-microbial compound triclosan is incorporated into numerous consumer products and is detectable in the urine of 75% of the general United States population. Recent epidemiological studies report positive associations with urinary triclosan levels and allergic disease. Although not sensitizing, earlier studies previously found that repeated topical application of triclosan augments the allergic response to ovalbumin (OVA) though a thymic stromal lymphopoietin (TSLP) pathway in mice. In the present study, early immunological effects following triclosan exposure were further evaluated following topical application in a murine model...
December 2017: Journal of Immunotoxicology
https://www.readbyqxmd.com/read/28120225/associations-between-urinary-polycyclic-aromatic-hydrocarbon-metabolites-and-serum-testosterone-in-u-s-adult-males-national-health-and-nutrition-examination-survey-2011-2012
#13
Lingling Wang, Weiyue Hu, Yankai Xia, Xinru Wang
Effects of environmental chemicals on human reproductive health and sex hormone levels have been reported for several years, but compared to other environmental chemicals, such as heavy metals, PCBs, triclosan, Phthalate, the links between polycyclic aromatic hydrocarbons (PAHs) and sex hormone levels have not been studied widely. Therefore, our purpose of research was to study the associations between urinary PAH metabolites and serum total testosterone (T) levels among men. The data was obtained from the independent cross-section wave (2011-2012) of the National Health and Nutrition Examination Survey (NHANES), including demographic, socioeconomic, dietary, health-related questions, examinations and laboratory test...
January 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28109710/univariate-predictors-of-maternal-concentrations-of-environmental-chemicals-the-mirec-study
#14
Antoine Lewin, Tye E Arbuckle, Mandy Fisher, Chun Lei Liang, Leonora Marro, Karelyn Davis, Nadia Abdelouahab, William D Fraser
BACKGROUND: The developing fetus and pregnant woman can be exposed to a variety of environmental chemicals that may adversely affect their health. Moreover, environmental exposure and risk disparities are associated with different social determinants, including socioeconomic status (SES) and demographic indicators. Our aim was to investigate whether and how maternal concentrations of a large panel of persistent and non-persistent environmental chemicals vary according to sociodemographic and lifestyle characteristics in a large pregnancy and birth cohort...
January 16, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28108888/biofilm-phosphorus-uptake-capacity-as-a-tool-for-the-assessment-of-pollutant-effects-in-river-ecosystems
#15
Lorenzo Proia, Anna Romaní, Sergi Sabater
Biofilms are a key component in the nutrient removal from the water column. However, nutrient uptake by biofilms may be hampered by the occurrence of pollutants or other stressors. This study aimed: (i) to investigate the biofilm phosphorus (P) uptake capacity as a relevant process for the maintenance of fluvial water quality and (ii) to explore the sensitivity of this process to different chemical and environmental stressors. We conducted chamber experiments to test for the relevance of biofilm P uptake capacity (PUC) as a tool to detect effects of pollutants on river self-depuration...
January 21, 2017: Ecotoxicology
https://www.readbyqxmd.com/read/28107972/electrochemical-sensor-for-sensitive-detection-of-triclosan-based-on-graphene-palladium-nanoparticles-hybrids
#16
Tingxuan Wu, Tingting Li, Zhiguang Liu, Yujing Guo, Chuan Dong
In this paper, poly (diallyldimethylammonium chloride) functionalized graphene/palladium nanoparticles (PDDA-Gr/PdNPs) have been successfully synthesized through a simple one-pot method with the use of PDDA as stabilizing agents. The electrochemical response of triclosan on the PDDA-Gr/PdNPs modified glassy carbon electrode (GCE) is greatly enhanced comparing to the PDDA-Gr/GCE or the bare GCE. It is suggested that the nanocomposite exhibited good electron transfer ability and catalytic activity. Under the optimal conditions, the oxidation current increased linearly with the concentration of triclosan in the range of 9...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28104659/complete-genome-sequence-of-the-triclosan-and-multidrug-resistant-pseudomonas-aeruginosa-strain-b10w-isolated-from-municipal-wastewater
#17
Chuanqing Zhong, Matthew Nelson, Guangxiang Cao, Michael J Sadowsky, Tao Yan
Here, we report the complete genome sequence of the triclosan- and multidrug-resistant Pseudomonas aeruginosa strain B10W, obtained from municipal wastewater in Hawaii. The bacterium has a 6.7-Mb genome, contains 6,391 coding sequences and 78 RNAs, with an average G+C content of 66.2 mol%.
January 19, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28104329/comparative-evaluation-of-four-biosolids-formulations-on-the-effects-of-triclosan-on-plant-arbuscular-mycorrhizal-fungal-interactions-in-three-crop-species
#18
René S Shahmohamadloo, Linda Lissemore, Ryan S Prosser, Paul K Sibley
Triclosan (TCS) is an antimicrobial ingredient found in personal care products that include soaps, shampoos, and other sanitation goods. TCS is moderately hydrophobic and has been shown to be resistant to wastewater treatment and thus accumulates in biosolids. Biosolids are commonly applied to agricultural land but little is known about the risk that TCS in biosolids poses to soil fungal communities following land application. The purpose of this study was to characterize the effects of TCS on the symbiotic colonization of roots in three field crops (soybean, corn, and spring wheat) by arbuscular mycorrhizal fungi (AMF) in soils amended with four different types of biosolids (liquid, dewatered, composted, alkaline and hydrolyzed)...
January 16, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28101706/comparative-assessment-of-leca-and-spartina-maritima-to-remove-emerging-organic-contaminants-from-wastewater
#19
Ana Rita Ferreira, Paula Guedes, Eduardo P Mateus, Alexandra B Ribeiro, Nazaré Couto
The present work aimed to evaluate the capacity of constructed wetlands (CWs) to remove three emerging organic contaminants with different physicochemical properties: caffeine (CAF), oxybenzone (MBPh), and triclosan (TCS). The simulated CWs were set up with a matrix of light expanded clay aggregates (LECA) and planted with Spartina maritima, a salt marsh plant. Controlled experiments were carried out in microcosms using deionized water and wastewater collected at a wastewater treatment plant (WWTP), with different contaminant mass ranges, for 3, 7, and 14 days...
January 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28096238/activation-of-trpa1-channel-by-antibacterial-agent-triclosan-induces-vegf-secretion-in-human-prostate-cancer-stromal-cells
#20
Sandra Derouiche, Pascal Mariot, Marine Warnier, Eric Vancauwenberghe, Gabriel Bidaux, Pierre Gosset, Brigitte Mauroy, Jean-Louis Bonnal, Christian Slomianny, Philippe Delcourt, Etienne Dewailly, Natalia Prevarskaya, Morad Roudbaraki
Accruing evidence indicates that exposure to environmental compounds may adversely impact human health and promote carcinogenesis. Triclosan (TCS), an antimicrobial agent widely used as a preservative in personal care products, has been shown to act as an endocrine disruptor in hormone-dependent tissues. Here we demonstrate a new molecular mechanism by which TCS stimulates the secretion by human prostate cancer stromal cells of Vascular Endothelial Growth Factor (VEGF), a factor known to promote tumour growth...
January 17, 2017: Cancer Prevention Research
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