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Triclosan

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https://www.readbyqxmd.com/read/28910731/triclosan-removal-from-surface-water-by-ozonation-kinetics-and-by-products-formation
#1
Kemal B Orhon, Aybala Koc Orhon, Filiz B Dilek, Ulku Yetis
Removal of triclosan from surface water by ozonation was investigated. The results showed that complete elimination of triclosan from a surface water bearing 1-5 mg/L triclosan via continuous ozonation at 5 mg/L, require an ozonation time of 20-30 min depending on pH. Triclosan oxidation followed pseudo-first order kinetics with an apparent reaction rate constant varying from 0.214 min(-1) to 0.964 min(-1) depending on pH, initial triclosan concentration and water composition. Although the effect of pH was complex due to possible existence of different moieties, higher TCS removal efficiencies were obvious at weak-base conditions...
September 11, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28902174/distribution-of-non-persistent-endocrine-disruptors-in-two-different-regions-of-the-human-brain
#2
Thomas P van der Meer, Francisco Artacho-Cordón, Dick F Swaab, Dicky Struik, Konstantinos C Makris, Bruce H R Wolffenbuttel, Hanne Frederiksen, Jana V van Vliet-Ostaptchouk
Non-persistent endocrine disrupting chemicals (npEDCs) can affect multiple organs and systems in the body. Whether npEDCs can accumulate in the human brain is largely unknown. The major aim of this pilot study was to examine the presence of environmental phenols and parabens in two distinct brain regions: the hypothalamus and white-matter tissue. In addition, a potential association between these npEDCs concentrations and obesity was investigated. Post-mortem brain material was obtained from 24 individuals, made up of 12 obese and 12 normal-weight subjects (defined as body mass index (BMI) > 30 and BMI < 25 kg/m², respectively)...
September 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28898861/removal-and-metabolism-of-triclosan-by-three-different-microalgal-species-in-aquatic-environment
#3
Shujuan Wang, Karen Poon, Zongwei Cai
Triclosan, an antimicrobial additive widely used in personal care products, has caused the contamination of various aquatic environment. Biodegradation was proved to play a vital role in the treatment of triclosan in wastewater. However, there is limited information about the metabolic pathway. In this study, three common freshwater microalgae including Chlorella pyrenoidosa (C. pyrenoidosa), Desmodesmus sp., and Scenedesmus obliquus (S. obliquus) were applied to remove and biodegrade triclosan in aqueous culture medium...
September 5, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28891010/effect-of-hydrophobicity-of-pharmaceuticals-and-personal-care-products-for-adsorption-on-activated-carbon-adsorption-isotherms-kinetics-and-mechanism
#4
Harkirat Kaur, Amit Bansiwal, Girivyankatesh Hippargi, Girish R Pophali
Adsorption of three pharmaceuticals and personal care products (PPCPs), namely caffeine, ibuprofen and triclosan on commercial powdered activated carbon was examined in aqueous medium. The contaminants were chosen based on their diverse log Kow (octanol-water partition coefficient) viz. - 0.07 for caffeine, 3.97 for ibuprofen and 4.76 for triclosan to examine the role of hydrophobicity on adsorption process. The adsorbent characterisation was achieved using BET surface area, SEM, pore size distribution studies and FTIR...
September 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28886593/influence-of-tetrabromobisphenol-a-with-or-without-concurrent-triclosan-upon-bisphenol-a-and-estradiol-concentrations-in-mice
#5
Tyler Pollock, Leanna Mantella, Vanessa Reali, Denys deCatanzaro
BACKGROUND: Humans are commonly exposed to multiple environmental chemicals, including tetrabromobisphenol A (TBBPA; a flame retardant), triclosan (an antimicrobial agent), and bisphenol A (BPA; polycarbonate plastics). These chemicals are readily absorbed and may interact with each other. OBJECTIVES: We sought to determine whether TBBPA, given alone or in combination with triclosan, can modulate the concentrations of BPA and 17β-estradiol (E2). METHODS: Female and male CF-1 mice were each given a subcutaneous injection of 0-27mg TBBPA, with or without concurrent 0...
August 21, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28885978/in-vitro-evaluation-of-mitochondrial-function-and-estrogen-signaling-in-cell-lines-exposed-to-the-antiseptic-cetylpyridinium-chloride
#6
Sandipan Datta, Guochun He, Alexey Tomilov, Sunil Sahdeo, Michael S Denison, Gino Cortopassi
BACKGROUND: Quaternary ammonium salts (QUATS), such as cetylpyridinium chloride (CPC) and benzalkonium chloride (BAK), are frequently used in antiseptic formulations, including toothpastes, mouthwashes, lozenges, throat and nasal sprays, and as biocides. Although in a recent ruling, the U.S. Food and Drug Administration (FDA) banned CPC from certain products and requested more data on BAK's efficacy and safety profile, QUATS, in general, and CPC and BAK, in particular, continue to be used in personal health care, food, and pharmaceutical and cleaning industries...
August 22, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28876132/removal-of-escherichia-coli-and-enterococcus-faecalis-after-hand-washing-with-antimicrobial-and-nonantimicrobial-soap-and-persistence-of-these-bacteria-in-rinsates
#7
J Pérez-Garza, S García, N Heredia
Food handlers are important sources of contamination in the agricultural environment. This study was conducted (i) to evaluate the activity of antimicrobial soaps against Escherichia coli and Enterococcus faecalis using a hand washing model with soiled hands and (ii) to determine the survival and persistence of these bacteria in rinsates. Sterilized agricultural soil from tomato and pepper farms was inoculated with E. coli or E. faecalis at 10(3) or 10(6) CFU/g. Decontaminated hands were placed in contact with contaminated soil for 2 min and were then washed with soaps with or without antimicrobial compounds (citric extracts, chloroxylenol, triclosan, or chlorhexidine gluconate)...
September 6, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28871466/salting-out-enhanced-ionic-liquid-microextraction-with-a-dual-role-solvent-for-simultaneous-determination-of-trace-pollutants-with-a-wide-polarity-range-in-aqueous-samples
#8
Man Gao, Jingang Qu, Kai Chen, Lide Jin, Randy Alan Dahlgren, Huili Wang, Chengxia Tan, Xuedong Wang
In real aquatic environments, many occupational pollutants with a wide range of polarities coexist at nanogram to milligram per liter levels. Most reported microextraction methods focus on extracting compounds with similar properties (e.g., polarity or specific functional groups). Herein, we developed a salting-out-enhanced ionic liquid microextraction based on a dual-role solvent (SILM-DS) for simultaneous detection of tetracycline, doxycycline, bisphenol A, triclosan, and methyltriclosan, with log K ow ranging from -1...
September 4, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28865372/impact-of-inoculum-sources-on-biotransformation-of-pharmaceuticals-and-personal-care-products
#9
Sunah Kim, Karen Rossmassler, Corey D Broeckling, Sarah Galloway, Jessica Prenni, Susan K De Long
Limited knowledge of optimal microbial community composition for PPCP biotreatment, and of the microbial phylotypes that drive biotransformation within mixed microbial communities, has hindered the rational design and operation of effective and reliable biological PPCP treatment technologies. Herein, bacterial community composition was investigated as an isolated variable within batch biofilm reactors via comparison of PPCP removals for three distinct inocula. Inocula pre-acclimated to model PPCPs were derived from activated sludge (AS), ditch sediment historically-impacted by wastewater treatment plant effluent (Sd), and material from laboratory-scale soil aquifer treatment (SAT) columns...
August 21, 2017: Water Research
https://www.readbyqxmd.com/read/28863962/in-vitro-efficacy-of-essential-oil-mouthrinse-versus-dentifrices
#10
Benjamin Serbiak, Tara Fourre, Anthony R Geonnotti, Robert J Gambogi
OBJECTIVES: To compare the antimicrobial efficacy and kill penetration of essential oils (EO) mouthrinse versus stannous fluoride, and triclosan dentifrice slurries on saliva-derived biofilms using confocal laser scanning microscopy (CLSM). METHODS: Saliva-derived biofilms were grown for 48hours on hydroxyapatite discs using pooled, homogenized saliva from 8 healthy volunteers as the inoculum. The mean thickness of these biofilms was 84μm (range, 23-241μm). CLSM with viability mapping was used to visualize the antimicrobial kill penetration of each treatment regime within a biofilm...
August 29, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28859275/investigation-of-triclosan-contamination-on-microbial-biomass-and-other-soil-health-indicators
#11
Morkel Zaayman, Alma Siggins, Dave Horne, Hamish Lowe, Jacqui Horswell
Triclosan (TCS) is an antimicrobial compound found in personal care products, and consequently in greywater. After its release to the environment, it continues its antimicrobial action on indigenous microbial communities. Little is known about the environmental impacts of high levels of TCS, which may occur due to accumulation following long-term greywater application to soil. Soil microcosms were established using a silty clay loam and augmented with a range of TCS concentrations ranging from 500 to 7500 mg kg-1...
September 1, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28844962/inhibitory-effects-of-3-3-diindolylmethane-on-epithelial-mesenchymal-transition-induced-by-endocrine-disrupting-chemicals-in-cellular-and-xenograft-mouse-models-of-breast-cancer
#12
Geum-A Lee, Kyung-A Hwang, Kyung-Chul Choi
As a phytoestrogen, 3,3'-diindolylmethane (DIM) plays a chemopreventive role by inhibiting cancer progression. In this study, we examined the effects of 17β-estradiol (E2), two endocrine disrupting chemicals (EDCs), triclosan (TCS) and bisphenol A (BPA), and DIM on epithelial-mesenchymal transition (EMT) and metastatic behaviors of estrogen receptor (ER)-positive MCF-7 breast cancer cells. An in vitro assay revealed that E2 (10(-9) M), TCS (10(-5)-10(-7) M), and BPA (10(-5)-10(-7) M) induced MCF-7 cell proliferation compared to a control through the ER pathway...
August 24, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28843737/toxic-effects-of-triclosan-on-a-zebrafish-danio-rerio-liver-cell-line-zfl
#13
Zhou Zhou, Jie Yang, King Ming Chan
Triclosan (TCS, 5-chloro-2-(2,4-dichlorophenoxy) phenol) is an antimicrobial agent widely used in personal care products. It has been detected in surface water, soil, aquatic species, and even humans. In this study, we used zebrafish (Danio rerio) as a model to test the hypothesis that TCS exhibits toxic effects by interacting with thyroid hormone receptor β (TRβ) and aryl hydrocarbon receptor (AhR) and by inducing the transcription of thyroid hormone (TH)-associated genes and affecting phase I and phase II enzymes...
August 19, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28837926/triclosan-tcs-and-triclocarban-tcc-induce-systemic-toxic-effects-in-a-model-organism-the-nematode-caenorhabditis-elegans
#14
Katrina A Lenz, Claire Pattison, Hongbo Ma
The broad application of triclosan (TCS) and triclocarban (TCC) as antimicrobials in household and personal care products has led to the concerns regarding their human health risk and environmental impact. Although many studies have examined the toxicological effects of these compounds to a wide range of aquatic organisms from algae to fish, their potential toxicity to an important model organism the nematode Caenorhabditis elegans has never been systematically investigated. Here we assessed the toxicological effects of TCS and TCC in C...
August 21, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28821116/active-release-coating-of-multilayer-assembled-branched-and-ionic-%C3%AE-cyclodextrins-onto-poly-ethylene-terephthalate
#15
Leyre Pérez-Álvarez, Leire Ruiz-Rubio, Erlantz Lizundia, Estíbaliz Hernáez, Luis M León, Jose Luis Vilas-Vilela
Branched ionic cyclodextrins multilayers were assembled onto the surface of previously aminolyzed poly(ethylene terephthalate) in order to construct local drug delivery tailored platforms with potential applicability as materials for indwelling medical devices. The construction of the multilayers took place by the alternate deposition of ionic cyclodextrin derivatives and was characterized by surface zeta-potential measurements, X-ray photoelectron spectroscopy and, after fluorescent labeling of anionic branched cyclodextrins, by UV-vis spectroscopy and confocal fluorescence spectroscopy...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28811083/phenotypic-chlorhexidine-and-triclosan-susceptibility-in-clinical-staphylococcus-aureus-isolates-in-australia
#16
C Hughes, J Ferguson
Antiseptics such as chlorhexidine gluconate and triclosan are widely used in healthcare settings for both skin antisepsis and decolonisation of Staphylococcus aureus. We determined the minimum inhibitory concentration (MIC) of 198 methicillin susceptible and resistant Staphylococcus aureus clinical isolates to both chlorhexidine and triclosan using an agar dilution method. Of these, 10% (19/198) showed a raised MIC to chlorhexidine and 3% (6/198) showed an elevated MIC to triclosan. The multilocus sequence type (MLST) of each isolate was predicted using a binary method, and although ST93-MRSA-IV was the most common, ST22-MRSA-IV was shown to have statistically higher chlorhexidine MIC values compared with non ST22-MRSA-IV isolates (z = -8...
August 12, 2017: Pathology
https://www.readbyqxmd.com/read/28808332/magnetic-microsphere-based-portable-solid-phase-extraction-device-for-on-site-pre-concentration-of-organics-from-large-volume-water-samples
#17
Zhijian Yao, Qingqing Zhao, Yan Ma, Wei Wang, Qing Zhou, Aimin Li
In this research a new magnetic material called M88 was fully synthetized and characterized for the extraction of pharmaceutical and personal care products in water samples. In addition, a portable prototype of magnetic solidphase extraction (MSPE) device was developed for the onsite preconcentration. The MSPE coupling with high performance liquid chromatography-Diode array detector (HPLC-DAD) method was developed and validated for simultaneous analysis of 11 PPCPs (mefenamic acid, chloroamphenicol, ketoprofen, clofibric acid, indometacin, acetylsalicylic acid, bisphenol A, phenylphenol, gemfibrozil, triclosan, and ibuprofen) in environmental water samples...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28800147/reduction-in-bacteremia-after-brushing-with-a-triclosan-copolymer-dentifrice-a-randomized-clinical-study
#18
P K Sreenivasan, D Tischio-Bereski, D H Fine
AIM: The aims of this study were to; 1) test susceptibility to bacteremia in subjects with moderate gingivitis, and 2) compare the effects of brushing with a fluoride toothpaste (control) as compared to a triclosan/copolymer toothpaste (test) on those susceptible to repeated bacteremia. MATERIALS AND METHODS: 107 adult subjects were tested for repeated bacteremia after eating a hard apple. 29 bacteremia positive subjects were enrolled in a double-blind cross-over study designed to analyze the effects of a test toothpaste...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28783897/gonadal-intersex-in-smallmouth-bass-micropterus-dolomieu-from-northern-indiana-with-correlations-to-molecular-biomarkers-and-anthropogenic-chemicals
#19
Ahmed Abdel-Moneim, Daragh Deegan, Jiejun Gao, Chloe De Perre, Jarrod S Doucette, Byron Jenkinson, Linda Lee, Maria S Sepúlveda
Over the past decade, studies have shown that exposure to endocrine disrupting chemicals (EDCs) can cause gonadal intersex in fish. Smallmouth bass (Micropterus dolomieu) males appear to be highly susceptible to developing testicular oocytes (TO), the most prevalent form of gonadal intersex, as observed in various areas across the U.S. In this study, prevalence and severity of TO was quantified for smallmouth bass sampled from the St. Joseph River in northern Indiana, intersex biomarkers were developed, and association between TO prevalence and organic contaminants were explored...
November 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28780452/the-impact-of-antibacterial-handsoap-constituents-on-the-dynamics-of-triclosan-dissolution-from-dry-sand
#20
Daniel A Koehler, Keith A Strevett, Charalambos Papelis, Tohren C G Kibbey
Triclosan has been widely used as an antibacterial agent in consumer and industrial products, and large quantities continue to be discharged to natural waters annually. The focus of this work was on studying the dynamics of triclosan dissolution following evaporative drying. Warm weather can cause the water in intermittent streams or the unsaturated zone to evaporate, causing nonvolatile compounds to form solid precipitates. Because dissolution of precipitates is a relatively slow process, the dynamics of dissolution following evaporation may play an important role in controlling the release of contaminants to the environment...
November 2017: Chemosphere
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