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https://www.readbyqxmd.com/read/27918734/protocols-for-management-of-oral-complications-of-chemotherapy-and-or-radiotherapy-for-oral-cancer-systematic-review-and-meta-analysis-current
#1
J-N Carneiro-Neto, J-D-S de-Menezes, L-B Moura, E-M-S Massucato, C-R de-Andrade
BACKGROUND AND OBJECTIVE: Considering the high possibility of dentist consult a patient with oral complications of chemotherapy and/or radiotherapy for oral cancer because of the advances in this area, this study aims to systematically review the literature to identify and suggest effective and safe protocols for the managements of oral complications in oncology patients. MATERIAL AND METHODS: The systematic review was designed by PICO and PRISMA including eligibility and exclusion criteria; the source of information and search strategy in PubMed according MeSH: "Mouth Neoplasms and Radiotherapy" and "Mouth Neoplasms and Drug Therapy" the period from 2010 to 2015; selection and data collection of study was carried form blind and independently by two researchers; risk of bias and methodological quality: ensured by the PEDro scale; synthesis of data: of oral complications were evaluated by adapted version of associative direction classification proposed by Costigan and collaborators; and data analysis was performed by the meta-analysis of BioEstat program (5...
December 6, 2016: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27916357/triclosan-sutures-for-surgical-site-infection-in-colorectal-cancer
#2
Kanefumi Yamashita, Shinsuke Takeno, Seiichiro Hoshino, Hironari Shiwaku, Naoya Aisu, Yoichiro Yoshida, Syu Tanimura, Yuichi Yamashita
BACKGROUND: Among all procedures, surgical site infections (SSIs) in colorectal surgery continue to have the highest rate, accounting for 5%-45%. To prevent the bacterial colonization of suture material, which disables local mechanisms of wound decontamination, triclosan-coated sutures were developed. We assessed the effectiveness of triclosan-coated sutures used for skin closure on the rate of SSIs in colorectal cancer surgery. METHODS: Until August 2012, we used conventional methods for skin closure in colorectal cancer surgery at the Department of Gastroenterological Surgery, Fukuoka University Faculty of Medicine...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27915141/a-review-of-the-occurrence-of-pharmaceuticals-and-personal-care-products-in-indian-water-bodies
#3
REVIEW
Keshava Balakrishna, Amlan Rath, Yerabham Praveenkumarreddy, Keerthi Siri Guruge, Bikram Subedi
Little information exists on the occurrence and the ultimate fate of pharmaceuticals in the water bodies in India despite being one of the world leaders in pharmaceutical production and consumption. This paper has reviewed 19 published reports of pharmaceutical occurrence in the aquatic environment in India [conventional activated sludge wastewater treatment plants (WTPs), hospital WTPs, rivers, and groundwater]. Carbamazepine (antipsychoactive), atenolol (antihypertensive), triclocarban and triclosan (antimicrobials), trimethoprim and sulfamethoxazole (antibacterials), ibuprofen and acetaminophen (analgesics), and caffeine (stimulant) are the most commonly detected at higher concentrations in Indian WTPs that treat predominantly the domestic sewage...
December 1, 2016: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/27914867/new-hbm-values-for-emerging-substances-inventory-of-reference-and-hbm-values-in-force-and-working-principles-of-the-german-human-biomonitoring-commission
#4
REVIEW
Petra Apel, Jürgen Angerer, Michael Wilhelm, Marike Kolossa-Gehring
The German Human Biomonitoring Commission (HBM Commission) derives health-related guidance values (Human Biomonitoring assessment values, HBM values) according to the procedures described in the HBM Commission's position papers. Since the last adaption of the methodology in 2014, the HBM Commission has established a series of new HBM values, mainly on the basis of internationally agreed TDI/RfD values, or of toxicologically well- founded points of departure observed in animal studies. The derivation of these new HBM values for HBCDD, triclosan, 2-MBT, PFOA and PFOS as well as for the metabolites of glycol ethers, of Hexamoll(®) DINCH(®), DPHP, DEHTP, NMP, NEP, and 4-MBC is specified, and the HBM values are presented together with already established HBM values for other substances...
September 17, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27909849/monitoring-contaminants-of-emerging-concern-from-tertiary-wastewater-treatment-plants-using-passive-sampling-modelled-with-performance-reference-compounds
#5
Tamanna Sultana, Craig Murray, M Ehsanul Hoque, Chris D Metcalfe
The Lake Simcoe watershed in Ontario, Canada is an important recreational area and a recharge zone for groundwater resources. Lake Simcoe is a relatively shallow lotic system that has been impacted by urban development, recreation, industry and agriculture. As part of a watershed management plan, six wastewater treatment plants (WWTPs) located in this catchment basin were selected to measure the inputs of contaminants of emerging concern (CECs) of wastewater origin. These WWTPs were recently upgraded to tertiary treatment for phosphorus removal...
December 2016: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27902959/kaempferol-a-phytoestrogen-suppressed-triclosan-induced-epithelial-mesenchymal-transition-and-metastatic-related-behaviors-of-mcf-7-breast-cancer-cells
#6
Geum-A Lee, Kyung-Chul Choi, Kyung-A Hwang
As a phytoestrogen, kaempferol is known to play a chemopreventive role inhibiting carcinogenesis and cancer progression. In this study, the influences of triclosan, an anti-bacterial agent recently known for an endocrine disrupting chemical (EDC), and kaempferol on breast cancer progression were examined by measuring their effects on epithelial-mesenchymal transition (EMT) and metastatic-related behaviors of MCF-7 breast cancer cells. Morphological changes of MCF-7 cells were observed, and a wound-healing assay was performed after the treatment of triclosan and kaempferol...
November 22, 2016: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/27898796/sorption-of-pharmaceuticals-heavy-metals-and-herbicides-to-biochar-in-the-presence-of-biosolids
#7
Daniel A Bair, Fungai N D Mukome, Inna E Popova, Temitope A Ogunyoku, Allie Jefferson, Daoyuan Wang, Sarah C Hafner, Thomas M Young, Sanjai J Parikh
Agricultural practices are increasingly incorporating recycled waste materials, such as biosolids, to provide plant nutrients and enhance soil functions. Although biosolids provide benefits to soil, municipal wastewater treatment plants receive pharmaceuticals and heavy metals that can accumulate in biosolids, and land application of biosolids can transfer these contaminants to the soil. Environmental exposure of these contaminants may adversely affect wildlife, disrupt microbial communities, detrimentally affect human health through long-term exposure, and cause the proliferation of antibiotic-resistant bacteria...
November 2016: Journal of Environmental Quality
https://www.readbyqxmd.com/read/27898309/diverging-temporal-trends-of-human-exposure-to-bisphenols-and-plastizisers-such-as-phthalates-caused-by-substitution-of-legacy-edcs
#8
Irina Gyllenhammar, Anders Glynn, Bo A G Jönsson, Christian H Lindh, Per Ola Darnerud, Kettil Svensson, Sanna Lignell
Phthalates and phenolic substances were investigated in urine samples from first-time mothers in Uppsala, Sweden, collected between 2009 and 2014. These substances have a comparably fast metabolism and urinary metabolites are predominantly analysed. The main aim was to investigate if measures to decrease production and use of certain phthalates and bisphenol A (BPA) have resulted in decreased human exposure, and to determine if exposures to replacement chemicals have increased. Temporal trends were evaluated for metabolites (n=13) of seven phthalates, a phthalate replacer, four different bisphenols, triclosan, one organophosphate-based flame retardant, and for two pesticides...
November 26, 2016: Environmental Research
https://www.readbyqxmd.com/read/27896399/cytochrome-p450-mediated-metabolism-of-triclosan-attenuates-its-cytotoxicity-in-hepatic-cells
#9
Yuanfeng Wu, Priyanka Chitranshi, Lucie Loukotková, Gonçalo Gamboa da Costa, Frederick A Beland, Jie Zhang, Jia-Long Fang
Triclosan is a widely used broad-spectrum anti-bacterial agent. The objectives of this study were to identify which cytochrome P450 (CYP) isoforms metabolize triclosan and to examine the effects of CYP-mediated metabolism on triclosan-induced cytotoxicity. A panel of HepG2-derived cell lines was established, each of which overexpressed a single CYP isoform, including CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2A7, CYP2A13, CYP2B6, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A5, CYP3A7, CYP4A11, and CYP4B1...
November 28, 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/27889169/characterization-of-biocide-tolerant-bacteria-isolated-from-cheese-and-dairy-small-medium-enterprises
#10
Ma Luisa Fernández Márquez, Ma José Grande Burgos, Ma Carmen López Aguayo, Rubén Pérez Pulido, Antonio Gálvez, Rosario Lucas
A collection of 120 bacterial isolates from small medium enterprises involved in the production of cow milk and the manufacture of goat cheese were screened for sensitivity to biocides benzalkonium chloride (BC), cetrimide (CT), hexadecylpyridinium chloride (HDP), triclosan (TC), hexachlorophene (CF) and poly-(hexamethylen guanidinium) hydrochloride (PHMG). Nineteen isolates were selected according to biocide tolerance and identified by 16S rDNA sequencing as Lactococcus sp. (6) Enterococcus sp. (1), Lactobacillus sp...
April 2017: Food Microbiology
https://www.readbyqxmd.com/read/27888119/prenatal-phthalate-triclosan-and-bisphenol-a-exposures-and-child-visual-spatial-abilities
#11
Joseph M Braun, David C Bellinger, Russ Hauser, Robert O Wright, Aimin Chen, Antonia M Calafat, Kimberly Yolton, Bruce P Lanphear
INTRODUCTION: During fetal development, sex steroids influence sexually dimorphic behaviors, such as visual-spatial abilities. Thus, endocrine disrupting chemicals that impact sex steroids during gestation may affect these behaviors. OBJECTIVE: We investigated the relationship between prenatal urinary phthalate metabolite, triclosan, and BPA concentrations and visual-spatial abilities in a prospective cohort of 198 mother-child dyads. METHODS: Data are from a prospective cohort in Cincinnati, OH (HOME Study)...
November 23, 2016: Neurotoxicology
https://www.readbyqxmd.com/read/27858272/urinary-arsenic-pesticides-heavy-metals-phthalates-polyaromatic-hydrocarbons-and-polyfluoroalkyl-compounds-are-associated-with-sleep-troubles-in-adults-usa-nhanes-2005-2006
#12
Ivy Shiue
Links between environmental chemicals and human health have emerged, but the effects on sleep health were less studied. Therefore, the aim of the present study was to investigate the relationships of different sets of environmental chemicals and common sleep troubles in a national and population-based setting. Data were retrieved from the United States National Health and Nutrition Examination Surveys, 2005-2006 including demographics, serum measurements, lifestyle factors, self-reported sleep troubles, and urinary environmental chemical concentrations...
November 17, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27857130/early-life-exposure-to-edcs-role-in-childhood-obesity-and-neurodevelopment
#13
REVIEW
Joseph M Braun
Endocrine-disrupting chemicals (EDCs) might increase the risk of childhood diseases by disrupting hormone-mediated processes that are critical for growth and development during gestation, infancy and childhood. The fetus, infant and child might have enhanced sensitivity to environmental stressors such as EDCs due to their rapid development and increased exposure to some EDCs as a consequence of development-specific behaviour, anatomy and physiology. In this Review, I discuss epidemiological studies examining the relationship between early-life exposure to bisphenol A (BPA), phthalates, triclosan and perfluoroalkyl substances (PFAS) with childhood neurobehavioural disorders and obesity...
November 18, 2016: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/27842808/branched-and-ionic-%C3%AE-cyclodextrins-multilayer-assembling-onto-polyacrylonitrile-membranes-for-removal-and-controlled-release-of-triclosan
#14
Leyre Pérez-Álvarez, Janire Matas, Flor Gómez-Galván, Leire Ruiz-Rubio, Luis M León, Jose Luis Vilas-Vilela
The present study summarizes the formation and characterization of multilayers of polyacrylonitrile (PAN) membranes with β-cyclodextrin derivatives in order to be potentially interesting for triclosan (TR) controlled delivery with antibacterial purposes, as well as, for the removal of TR from wastewater. With this object, cationic and anionic branched β-cyclodextrins (bβCDs) were incorporated by layer-by-layer (LbL) process onto previously synthesized and hydrolyzed PAN membranes. FTIR, XPS and labelling with fluoresceinamine (FA) let to study the formation and stability of the prepared multilayered systems...
January 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27842719/laccase-and-electrochemically-mediated-conversion-of-triclosan-metabolite-formation-and-influence-on-antibacterial-activity
#15
Elham Jahangiri, Bettina Seiwert, Thorsten Reemtsma, Dietmar Schlosser
Metabolite formation from radical-based oxidation of the environmental pollutant triclosan (TCS) was compared using an ascomycete (Phoma sp. UHH 5-1-03) and a basidiomycete (Trametes versicolor) laccase, laccase-redox mediator systems, and electrochemical oxidation (EC). Laccase oxidation predominantly yielded TCS di- and trimers, but notably also caused TCS ether bond cleavage. The latter was more prominent during EC-catalysed TCS oxidation, which generally resulted in a broader and more divergent product spectrum...
November 11, 2016: Chemosphere
https://www.readbyqxmd.com/read/27835926/mouthwashes-in-the-21-st-century-a-narrative-review-about-active-molecules-and-effectiveness-on-the-periodontal-outcomes
#16
Gianluca M Tartaglia, Santhosh Kumar, Claudia Debora Fornari, Eleonora Corti, Stephen Thaddeus Connelly
Poor oral hygiene is a major risk factor for oral diseases. Regular home-based care is essential to maintain good oral hygiene. In particular, mouthrinses can support conventional tooth brushing in reducing accumulation of oral plaque. Areas covered: The most common molecules contained in mouthrinses (chlorhexidine, essential oils, cetyl pyridinium chloride, triclosan, octeneidine, delmopinol, polyvinylpyrrolidone, hyaluronic acid, natural compounds) are discussed, together with relevant clinical and in vitro studies, focusing on their effects on periodontal health...
November 20, 2016: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/27826723/performance-and-mechanism-of-triclosan-removal-in-simultaneous-nitrification-and-denitrification-snd-process-under-low-oxygen-condition
#17
Junhua Liu, Jingmin Wang, Congcong Zhao, Jianing Liu, Huijun Xie, Shuning Wang, Jian Zhang, Zhen Hu
Wastewater treatment under low dissolved oxygen (DO) conditions is promising for its low energy consumption. However, the removal process of some organic micropollutants, such as triclosan (TCS), could be inhibited under anaerobic conditions. So, it is worth investigating the TCS removal performance at low-oxygen condition. In this study, simultaneous nitrification and denitrification (SND) process, with DO ranging from 0.30 to 0.80 mg L(-1), was chosen to investigate. Results showed that the water quality of the effluent was deteriorated after TCS addition at the beginning, with removal efficiency of NH4(+)-N dropped from almost 100 ± 0...
November 8, 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27823864/transformation-of-triclosan-by-laccase-catalyzed-oxidation-the-influence-of-humic-acid-metal-binding-process
#18
Junhe Lu, Yuanyuan Shi, Yuefei Ji, Deyang Kong, Qingguo Huang
Laccase is a widely present extracellular phenoloxidase excreted by fungi, bacteria, and high plants. It is able to catalyze one-electron oxidation of phenolic compounds into radical intermediates that can subsequently couple to each other via covalent bonds. These reactions are believed to play an important role in humification process and the transformation of contaminants containing phenolic functionalities in the environment. In this study, we investigated the kinetics of triclosan transformation catalyzed by laccase...
January 2017: Environmental Pollution
https://www.readbyqxmd.com/read/27816435/a-review-of-human-biomonitoring-data-used-in-regulatory-risk-assessment-under-canada-s-chemicals-management-program
#19
REVIEW
Angelika Zidek, Kristin Macey, Leona MacKinnon, Mikin Patel, Devika Poddalgoda, Yi Zhang
As a part of the Chemicals Management Plan launched in 2006, the Government of Canada is assessing and managing, where appropriate, the potential health and ecological risks associated with approximately 4300 substances under the Canadian Environmental Protection Act (1999). Since that time, nearly 3000 substances have been assessed, with human biomonitoring (HBM) data playing an increasingly important role for some substances. Case studies are presented, including both inorganic and organic substances (i.e...
October 21, 2016: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/27810681/changes-in-mammary-histology-and-transcriptome-profiles-by-low-dose-exposure-to-environmental-phenols-at-critical-windows-of-development
#20
Kalpana Gopalakrishnan, Susan L Teitelbaum, Luca Lambertini, James Wetmur, Fabiana Manservisi, Laura Falcioni, Simona Panzacchi, Fiorella Belpoggi, Jia Chen
Exposure to environmental chemicals has been linked to altered mammary development and cancer risk at high doses using animal models. Effects at low doses comparable to human exposure remain poorly understood, especially during critical developmental windows. We investigated the effects of two environmental phenols commonly used in personal care products - methyl paraben (MPB) and triclosan (TCS) - on the histology and transcriptome of normal mammary glands at low doses mimicking human exposure during critical windows of development...
January 2017: Environmental Research
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