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https://www.readbyqxmd.com/read/29923604/incidence-and-prevalence-of-antibody-to-hepatitis-c-virus-in-fdny-first-responders-before-and-after-work-at-the-world-trade-center-disaster-site
#1
Mayris P Webber, Yang Liu, Hillel W Cohen, Theresa Schwartz, Michael D Weiden, Kerry Kelly, Viola Ortiz, Rachel Zeig-Owens, Nadia Jaber, Hilary L Colbeth, David J Prezant
BACKGROUND: The goals of this study were to assess the impact of work at the World Trade Center (WTC) site in relation to new, post-9/11/2001 (9/11) antibody to hepatitis C Virus (anti-HCV); and, evaluate secular trends in WTC-exposed male Fire Department of New York City (FDNY) Firefighters and Emergency Medical Services (EMS) responders. METHODS: FDNY monitors responder health through physical exams and routine blood work. We used descriptive statistics to compare trans-9/11 and post-9/11 incidence and to assess trends in prevalence from 2000 to 2012...
June 20, 2018: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29907850/behavior-problems-in-adolescence-and-subsequent-mental-health-in-early-adulthood-results-from-the-world-trade-center-health-registry-cohort
#2
Lisa M Gargano, Sean Locke, Jiehui Li, Mark R Farfel
BACKGROUND: The present study examined the association between 9/11-related adolescent behavioral problems on mental health outcomes in early adulthood. METHODS: Data from enrollees of the World Trade Center Health Registry, who completed at least one adolescent (2006-2007 or 2011-2012) and adult survey (2011-2012 or 2015-2016), were analyzed. Adolescent behavioral difficulties were assessed using the adolescent-reported Strengths and Difficulties Questionnaire (SDQ)...
June 15, 2018: Pediatric Research
https://www.readbyqxmd.com/read/29905642/alcohol-and-drug-related-mortality-among-enrollees-in-the-world-trade-center-health-registry-wtchr-2004-12
#3
Alice E Welch, Kimberly Caramanica Zweig, Tim Liao, Jennifer Yip, Alexander Davidson, Hannah Jordan, Robert Brackbill, James Cone
OBJECTIVE: Have World Trade Center Health Registry (WTCHR) enrollees experienced increased alcohol and drug-related mortality associated with exposures to the events of 9/11/01? METHODS: Cases involving death due to alcohol or drugs between 2003 and 2012 in New York City (NYC) were obtained through a match of the Registry with NYC Vital Records. We compared ICD-10-coded deaths where alcohol and/or drug use was the underlying cause of death to deaths from all other causes...
June 13, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29882850/asthma-among-world-trade-center-first-responders-a-qualitative-synthesis-and-bias-assessment
#4
REVIEW
Hyun Kim, Navneet Kaur Baidwan, David Kriebel, Manuel Cifuentes, Sherry Baron
The World Trade Center (WTC) disaster exposed the responders to several hazards. Three cohorts i.e., the Fire Department of New York (FDNY), the General Responder Cohort (GRC), and the WTC Health Registry (WTCHR) surveyed the exposed responder population. We searched Pubmed and Web of Science for literature on a well-published association between the WTC exposures and asthma, focusing on new-onset self-reported physician-diagnosed asthma. The resulting five articles were qualitatively assessed for potential biases...
May 23, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29851739/risk-of-stroke-among-survivors-of-the-september-11-2001-world-trade-center-disaster
#5
Shengchao Yu, Howard E Alper, Angela-Maithy Nguyen, Robert M Brackbill
OBJECTIVE: The aim of this study was to investigate the association between 9/11-related posttraumatic stress disorder (PTSD), dust cloud exposure, and subsequent development of stroke among 42,527 enrollees in the World Trade Center (WTC) Health Registry. METHODS: Using four waves of longitudinal data from the WTC Health Registry surveys, we employed Cox proportional hazards regression models to assess the associations. RESULTS: Incidence of stroke was higher among those with PTSD or intense dust cloud exposure than those without, and it was even higher for those who had experienced both...
May 30, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29797069/increased-airway-wall-thickness-is-associated-with-adverse-longitudinal-first-second-forced-expiratory-volume-trajectories-of-former-world-trade-center-workers
#6
Rafael E de la Hoz, Xiaoyu Liu, John T Doucette, Anthony P Reeves, Laura A Bienenfeld, Juan P Wisnivesky, Juan C Celedón, David A Lynch, Raúl San José Estépar
RATIONALE: Occupational exposures at the WTC site after September 11, 2001 have been associated with several presumably inflammatory lower airway diseases. In this study, we describe the trajectories of expiratory air flow decline, identify subgroups with adverse progression, and investigate the association of a quantitative computed tomography (QCT) imaging measurement of airway wall thickness, and other risk factors for adverse progression. METHODS: We examined the trajectories of expiratory air flow decline in a group of 799 former WTC workers and volunteers with QCT-measured (with two independent systems) wall area percent (WAP) and at least 3 periodic spirometries...
May 24, 2018: Lung
https://www.readbyqxmd.com/read/29764808/9-11-firefighters-at-risk-for-multiple-myeloma
#7
(no author information available yet)
The largest study to date of responders to the World Trade Center attacks in New York, NY, on 9/11 reports that exposed firefighters have roughly twice the risk of developing multiple myeloma precursor disease as the general population. Moreover, firefighters who go on to develop multiple myeloma exhibit a younger age of onset and more aggressive disease than is typical.
May 15, 2018: Cancer Discovery
https://www.readbyqxmd.com/read/29735001/obstructive-sleep-apnea-in-community-members-exposed-to-world-trade-center-dust-and-fumes
#8
Shilpi Ahuja, Zhaoyin Zhu, Yongzhao Shao, Kenneth I Berger, Joan Reibman, Omer Ahmed
STUDY OBJECTIVES: A relationship between obstructive sleep apnea (OSA) and exposure to the World Trade Center (WTC) dust and fumes has been suggested in responders but little is known about a possible relationship in community members. We characterized sleep studies performed in community members with WTC dust exposure to improve our understanding of the relationship between the diagnosis and severity of OSA and WTC dust exposure in this population. METHODS: Single-center, retrospective study of patients enrolled in a clinical treatment program for community members with WTC dust exposure...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29710327/some-thoughts-on-exposure-to-the-world-trade-center-wreckage-and-cancer
#9
Otis W Brawley
No abstract text is available yet for this article.
June 1, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29710195/multiple-myeloma-and-its-precursor-disease-among-firefighters-exposed-to-the-world-trade-center-disaster
#10
Ola Landgren, Rachel Zeig-Owens, Orsolya Giricz, David Goldfarb, Kaznouri Murata, Katie Thoren, Lakshmi Ramanathan, Malin Hultcrantz, Ahmet Dogan, George Nwankwo, Ulrich Steidl, Kith Pradhan, Charles B Hall, Hillel W Cohen, Nadia Jaber, Theresa Schwartz, Laura Crowley, Michael Crane, Shani Irby, Mayris P Webber, Amit Verma, David J Prezant
Importance: The World Trade Center (WTC) attacks on September 11, 2001, created an unprecedented environmental exposure to known and suspected carcinogens suggested to increase the risk of multiple myeloma. Multiple myeloma is consistently preceded by the precursor states of monoclonal gammopathy of undetermined significance (MGUS) and light-chain MGUS, detectable in peripheral blood. Objective: To characterize WTC-exposed firefighters with a diagnosis of multiple myeloma and to conduct a screening study for MGUS and light-chain MGUS...
June 1, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29710126/estimation-of-future-cancer-burden-among-rescue-and-recovery-workers-exposed-to-the-world-trade-center-disaster
#11
Ankura Singh, Rachel Zeig-Owens, William Moir, Charles B Hall, Theresa Schwartz, Madeline Vossbrinck, Nadia Jaber, Mayris P Webber, Kerry J Kelly, Viola Ortiz, Ellen Koffler, David J Prezant
Importance: Elevated rates of cancer have been reported in individuals exposed to the World Trade Center (WTC) disaster, including Fire Department of the City of New York (FDNY) rescue and recovery workers. Objective: To project the future burden of cancer in WTC-exposed FDNY rescue and recovery workers by estimating the 20-year cancer incidence. Design, Setting, and Participants: A total of 14 474 WTC-exposed FDNY employees who were cancer-free on January 1, 2012; subgroup analyses were conducted of the cohort's white male population (n = 12 374)...
June 1, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29681931/development-of-a-physiological-frailty-index-for-the-world-trade-center-general-responder-cohort
#12
Ghalib A Bello, Roberto G Lucchini, Susan L Teitelbaum, Moshe Shapiro, Michael A Crane, Andrew C Todd
Responders to the 9/11/2001 WTC attacks were exposed to multiple toxic pollutants. Since 2002, the health of the responder cohort has been continuously tracked by the WTC Health Monitoring Program. However, no assessments have been made of frailty, an important health metric given the current average age of the WTC responder cohort (55 years). In this study, we use laboratory test results and other physiological parameters to construct a physiological frailty index (FI-Lab) for this cohort. The study sample comprised responders aged 40 years or older who completed a health monitoring visit at Mount Sinai Center within the past 5 years...
2018: Current Gerontology and Geriatrics Research
https://www.readbyqxmd.com/read/29676627/effect-of-world-trade-center-dust-exposure-and-chronic-intermittent-hypoxia-on-macrophage-matrix-metalloproteinase-12-expression-in-mice
#13
Jared Radbel, Oanh Le-Hoang, Kinal N Vayas, Kaiwal Patel, Michael Goedken, Vasanthi R Sunil, Debra Laskin, Jag Sunderram
RATIONALE: The pathophysiologic mechanisms by which World Trade Center (WTC) dust exposure leads to pulmonary disease have not been established. Matrix metalloproteinase-12 (MMP-12) is involved in the development of pulmonary fibrosis and chronic obstructive pulmonary disease. We have previously shown that exposure of mice to WTC dust results in increased expression of matrix metalloproteinase 12 by alveolar macrophages. Matrix metalloproteinase 12 expression is regulated, in part, by oxidative stress, which is also increased after WTC dust exposure...
April 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29643263/health-state-utilities-for-patient-s-current-health-from-bipolar-type-i-disorder
#14
Masoumeh Banihashemian, Arash Rashidian, Faeze Gholamian, Mahboubeh Parsaeian, Najmeh Moradi, Homayoun Amini
BACKGROUND: Bipolar Type I Disorder (BID) is a disabling mental disorder among young adults that places enormous psychological, social, and economic burdens on patients, their families, and health care systems and decreases quality of life (QOL). Few studies have investigated the quality-adjusted life-years (QALY), health state preferences, and utilities in patients with BID. AIM OF STUDY: The aim of this study was to elicit health state utilities for current health among a sample of individuals with BID irrespective of their clinical conditions at the time of evaluation...
March 1, 2018: Journal of Mental Health Policy and Economics
https://www.readbyqxmd.com/read/29627406/post-9-11-drug-and-alcohol-related-hospitalizations-among-world-trade-center-health-registry-enrollees-2003-2010
#15
Andrew Hirst, Sara A Miller-Archie, Alice E Welch, Jiehui Li, Robert M Brackbill
OBJECTIVE: To describe patterns of drug- and alcohol-related hospitalizations among persons exposed to the 2001 World Trade Center (WTC) terrorist attacks and to assess whether 9/11-related exposures or post-9/11 post-traumatic stress disorder (PTSD) were associated with increased odds of hospitalization. METHODS: Data for adult enrollees in the WTC Health Registry, a prospective cohort study, were linked to New York State (NYS) administrative hospitalization data to identify alcohol- and drug-related hospitalizations from enrollment to December 31, 2010...
June 1, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29580634/the-relationship-between-posttraumatic-and-depressive-symptoms-during-virtual-reality-exposure-therapy-with-a-cognitive-enhancer
#16
Melissa Peskin, Katarzyna Wyka, Judith Cukor, Megan Olden, Margaret Altemus, Francis S Lee, JoAnn Difede
Two studies suggest that reductions in posttraumatic symptoms (Aderka et al., 2013) and cognitions (Zalta et al., 2014) precede reductions in depressive symptoms during prolonged exposure (PE) therapy for posttraumatic stress disorder (PTSD) in female assault survivors. The present study explored the temporal relationship between posttraumatic and depressive symptoms in a randomized trial of D-Cycloserine (DCS) versus placebo augmented virtual reality exposure (VRE) therapy for chronic World Trade Center-related PTSD following the September 11, 2001 terrorist attacks...
March 10, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29574927/parental-posttraumatic-stress-and-child-behavioral-problems-in-world-trade-center-responders
#17
Mai Uchida, Huifen Feng, Adriana Feder, Natalie Mota, Clyde B Schechter, Hilary D Woodworth, Caroline G Kelberman, Michael Crane, Philip Landrigan, Jacqueline Moline, Iris Udasin, Denise Harrison, Benjamin J Luft, Craig Katz, Steven M Southwick, Robert H Pietrzak
BACKGROUND: We investigated trans-generational associations between Post Traumatic Stress Disorder (PTSD) symptoms in World Trade Center (WTC) responders and behavioral problems in their children. METHODS: Participants were WTC responders-8034 police and 8352 non-traditional (eg, construction workers)-with one or more children at the time of their first visit to the World Trade Center Health Program (WTC-HP). Self-report questionnaires were administered approximately 4 years after the 9/11 WTC attack...
June 2018: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29543564/chest-ct-scan-findings-in-world-trade-center-workers
#18
Rafael E de la Hoz, Jonathan Weber, Dongming Xu, John T Doucette, Xiaoyu Liu, Deborah A Carson, Juan C Celedón
We examined the chest CT scans of 1,453 WTC responders using the International Classification of High-resolution CT for Occupational and Environmental Respiratory Diseases. Univariate and bivariate analyses of potential work-related pleural abnormalities were performed with pre-WTC and WTC-related occupational exposure data, spirometry, demographics and quantitative CT measurements. Logistic regression was used to evaluate occupational predictors of those abnormalities. Chest CT scans were performed first at a median of 6...
March 15, 2018: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/29539098/posttraumatic-stress-disorder-functional-impairment-and-subjective-distress-in-world-trade-center-disaster-workers
#19
Kallio Hunnicutt-Ferguson, Katarzyna E Wyka, Melissa Peskin, Judith Cukor, Megan Olden, JoAnn Difede
Posttraumatic stress disorder (PTSD) is associated with functional deficits, poor physical health, and diminished quality of life. Limited research has examined PTSD symptom clusters and their associations with functioning and distress among disaster recovery workers, a population at high risk for PTSD due to potential for repeated trauma. The purpose of this study was to investigate associations between overall PTSD severity, as well as PTSD symptom clusters, and social and occupational functioning and subjective distress in World Trade Center (WTC) disaster workers after the terrorist attacks on September 11, 2001 (9/11)...
April 2018: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29508426/standardized-morbidity-ratios-of-four-chronic-health-conditions-among-world-trade-center-responders-comparison-to-the-national-health-interview-survey
#20
Hyun Kim, David Kriebel, Bian Liu, Sherrry Baron, Steven Mongin, Navneet K Baidwan, Jacqueline M Moline
PURPOSE: We conducted external comparisons for the prevalence of asthma, hypertension, diabetes, and cancer among World Trade Center (WTC) general responders using the National Health Interview Survey (NHIS) as the reference, along with internal comparisons for the incidence of asthma. METHODS: Standardized Morbidity Ratios (SMRs) were calculated for the prevalence of the health conditions, and risk ratios (RRs) for asthma incidence. RESULTS: Relative to the NHIS, asthma prevalence was in excess in responders over the study years (age-adjusted SMRs = 1...
May 2018: American Journal of Industrial Medicine
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