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https://www.readbyqxmd.com/read/28181152/airway-disease-in-rescue-recovery-workers-recent-findings-from-the-world-trade-center-collapse
#1
REVIEW
Krystal L Cleven, Mayris P Webber, Rachel Zeig-Owens, Kerry M Hena, David J Prezant
PURPOSE OF REVIEW: Our goal is to summarize the airway disease literature since September 11, 2001 (9/11), focusing on studies published since 2011 in World Trade Center-exposed rescue/recovery workers. RECENT FINDINGS: Since 2011, studies have confirmed relationships between initial World Trade Center exposure intensity, severity of symptoms, airway disease diagnoses, and biomarkers of disease progression. Studies continue to document ongoing morbidity in rescue/recovery workers over 10 years after 9/11...
January 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28157767/paresthesias-among-community-members-exposed-to-the-world-trade-center-disaster
#2
Michael Marmor, Yongzhao Shao, D Harshad Bhatt, Mark M Stecker, Kenneth I Berger, Roberta M Goldring, Rebecca L Rosen, Caralee Caplan-Shaw, Angeliki Kazeros, Deepak Pradhan, Marc Wilkenfeld, Joan Reibman
OBJECTIVE: Paresthesias can result from metabolic disorders, nerve entrapment following repetitive motions, hyperventilation pursuant to anxiety, or exposure to neurotoxins. We analyzed data from community members exposed to the World Trade Center (WTC) disaster of September 11, 2001, to evaluate whether exposure to the disaster was associated with paresthesias. METHODS: Analysis of data from 3141 patients of the WTC Environmental Health Center. RESULTS: Fifty-six percent of patients reported paresthesias at enrollment 7 to 15 years following the WTC disaster...
February 2, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28135632/elevated-c-reactive-protein-and-posttraumatic-stress-pathology-among-survivors-of-the-9-11-world-trade-center-attacks
#3
Rebecca L Rosen, Nomi Levy-Carrick, Joan Reibman, Ning Xu, Yongzhao Shao, Mengling Liu, Lucia Ferri, Angeliki Kazeros, Caralee E Caplan-Shaw, Deepak R Pradhan, Michael Marmor, Isaac R Galatzer-Levy
BACKGROUND: Systemic inflammation has emerged as a promising marker and potential mechanism underlying post-traumatic stress disorder (PTSD). The relationship between posttraumatic stress pathology and systemic inflammation has not, however, been consistently replicated and is potentially confounded by comorbid illness or injury, common complications of trauma exposure. METHODS: We analyzed a large naturalistic cohort sharing a discrete physical and mental health trauma from the destruction of the World Trade Center (WTC) towers on September 11, 2001 (n = 641)...
January 16, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28109459/intensity-of-binge-drinking-a-decade-after-the-september-11th-terror-attacks-among-exposed-individuals
#4
Alice E Welch, Kimberly Caramanica Zweig, Jonathan M McAteer, Robert M Brackbill
INTRODUCTION: The 9/11 terrorist attacks on the World Trade Center resulted in elevated post-traumatic stress disorder (PTSD) and alcohol use among exposed individuals. The relationship among traumatic exposure, PTSD, and excessive drinking is well documented; however, little is known about these relationships in the long term. This study examines factors increasing binge drinking risk among exposed individuals a decade post-9/11. METHODS: In 2015-2016, data were analyzed from 28,592 World Trade Center Health Registry enrollees aged ≥18 years who completed the Wave 3 (2011-2012) survey...
February 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28104511/serum-perfluoroalkyl-substances-in-children-exposed-to-the-world-trade-center-disaster
#5
Leonardo Trasande, Tony T Koshy, Joseph Gilbert, Lauren K Burdine, Teresa M Attina, Akhgar Ghassabian, Masato Honda, Michael Marmor, Dinh Binh Chu, Xiaoxia Han, Yongzhao Shao, Kurunthachalam Kannan
The World Trade Center (WTC) disaster released large amounts of various chemical substances into the environment, including perfluoroalkyl substances (PFASs). Yet, no studies have examined exposures in children living or attending schools near the disaster site. We measured serum PFASs in WTC Health Registry (WTCHR) respondents who were ≤8 years of age on September 11, 2001 and a sociodemographically-matched comparison group. We also examined the relationship of PFASs levels with dust cloud exposure; home dust exposure, and with traumatic exposure, the latter to take into account differences related to possible mental health consequences and associated behavioral problems...
January 16, 2017: Environmental Research
https://www.readbyqxmd.com/read/28099776/understanding-the-connection-between-posttraumatic-stress-symptoms-and-respiratory-problems-contributions-of-anxiety-sensitivity
#6
Brittain L Mahaffey, Adam Gonzalez, Samantha G Farris, Michael J Zvolensky, Evelyn J Bromet, Benjamin J Luft, Roman Kotov
Respiratory problems and posttraumatic stress disorder (PTSD) are the signature health consequences associated with the September 11, 2001 (9/11), World Trade Center disaster and frequently co-occur. The reasons for this comorbidity, however, remain unknown. Anxiety sensitivity is a transdiagnostic trait that is associated with both PTSD and respiratory symptoms. The present study explored whether anxiety sensitivity could explain the experience of respiratory symptoms in trauma-exposed smokers with PTSD symptoms...
February 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28061835/a-comparative-assessment-of-major-international-disasters-the-need-for-exposure-assessment-systematic-emergency-preparedness-and-lifetime-health-care
#7
Roberto G Lucchini, Dana Hashim, Sushma Acquilla, Angela Basanets, Pier Alberto Bertazzi, Andrey Bushmanov, Michael Crane, Denise J Harrison, William Holden, Philip J Landrigan, Benjamin J Luft, Paolo Mocarelli, Nailya Mazitova, James Melius, Jacqueline M Moline, Koji Mori, David Prezant, Joan Reibman, Dori B Reissman, Alexander Stazharau, Ken Takahashi, Iris G Udasin, Andrew C Todd
BACKGROUND: The disasters at Seveso, Three Mile Island, Bhopal, Chernobyl, the World Trade Center (WTC) and Fukushima had historic health and economic sequelae for large populations of workers, responders and community members. METHODS: Comparative data from these events were collected to derive indications for future preparedness. Information from the primary sources and a literature review addressed: i) exposure assessment; ii) exposed populations; iii) health surveillance; iv) follow-up and research outputs; v) observed physical and mental health effects; vi) treatment and benefits; and vii) outreach activities...
January 7, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28042514/quality-of-life-of-persons-injured-on-9-11-qualitative-analysis-from-the-world-trade-center-health-registry
#8
Lisa M Gargano, Robyn R Gershon, Robert M Brackbill
INTRODUCTION: A number of studies published by the World Trade Center Health Registry (Registry) document the prevalence of injuries sustained by victims of the World Trade Center Disaster (WTCD) on 9/11. Injury occurrence during or in the immediate aftermath of this event has been shown to be a risk factor for long-term adverse physical and mental health status. More recent reports of ongoing physical health and mental health problems and overall poor quality of life among survivors led us to undertake this qualitative study to explore the long-term impact of having both disaster-related injuries and peri-event traumatic exposure on quality of life in disaster survivors...
October 27, 2016: PLoS Currents
https://www.readbyqxmd.com/read/28032532/the-missing-the-martyred-and-the-disappeared-global-networks-technical-intensification-and-the-end-of-human-rights-genetics
#9
Lindsay A Smith
In 1984, a group of Argentine students, trained by US academics, formed the Argentine Forensic Anthropology Team to apply the latest scientific techniques to the excavation of mass graves and identification of the dead, and to work toward transitional justice. This inaugurated a new era in global forensic science, as groups of scientists in the Global South worked outside of and often against local governments to document war crimes in post-conflict settings. After 2001, however, with the inauguration of the war on terror following the September 11(th) attacks on the World Trade Center in New York, global forensic science was again remade through US and European investment to increase preparedness in the face of potential terrorist attacks...
December 1, 2016: Social Studies of Science
https://www.readbyqxmd.com/read/28030758/world-trade-center-health-program-amendments-to-definitions-appeals-and-other-requirements-final-rule
#10
(no author information available yet)
In 2011 and 2012, the Secretary, Department of Health and Human Services (HHS), promulgated regulations designed to govern the World Trade Center (WTC) Health Program (Program), including the processes by which eligible responders and survivors may apply for enrollment in the Program, obtain health monitoring and treatment for WTC-related health conditions, and appeal enrollment and treatment decisions, as well as a process to add new conditions to the List of WTC-Related Health Conditions (List). After using the regulations for a number of years, the Administrator of the WTC Health Program identified potential improvements to certain existing provisions, including, but not limited to, appeals of enrollment, certification, and treatment decisions, as well as the procedures for the addition of health conditions for WTC Health Program coverage...
15, 2016: Federal Register
https://www.readbyqxmd.com/read/28013272/trauma-focused-smoking-cessation-for-smokers-exposed-to-the-world-trade-center-disaster-a-randomized-clinical-trial
#11
Adam Gonzalez, Fred Friedberg, Xiaotong Li, Michael J Zvolensky, Evelyn J Bromet, Brittain L Mahaffey, Anka A Vujanovic, Benjamin J Luft, Roman Kotov
INTRODUCTION: The main objective was to evaluate the efficacy of an 8-session, group-based comprehensive smoking cessation and trauma management (CSC-T) treatment among daily smokers (≥ 5 cigarettes/day) exposed to the WTC disaster with elevated WTC-related PTSD symptoms. METHODS: Participants (N=90) were randomly assigned to CSC-T (N=44; 63.6% White; 27.3% female; mean age = 51.32±7.87) or comprehensive smoking cessation (CSC) alone (N=46; 71.7% White; 28.3% female; mean age=48...
December 24, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27986442/world-trade-center-wtc-dust-exposure-in-mice-is-associated-with-inflammation-oxidative-stress-and-epigenetic-changes-in-the-lung
#12
Vasanthi R Sunil, Kinal N Vayas, Mingzhu Fang, Helmut Zarbl, Christopher Massa, Andrew J Gow, Jessica A Cervelli, Howard Kipen, Robert J Laumbach, Paul J Lioy, Jeffrey D Laskin, Debra L Laskin
Exposure to World Trade Center (WTC) dust has been linked to respiratory disease in humans. In the present studies we developed a rodent model of WTC dust exposure to analyze lung oxidative stress and inflammation, with the goal of elucidating potential epigenetic mechanisms underlying these responses. Exposure of mice to WTC dust (20μg, i.t.) was associated with upregulation of heme oxygenase-1 and cyclooxygenase-2 within 3days, a response which persisted for at least 21days. Whereas matrix metalloproteinase was upregulated 7days post-WTC dust exposure, IL-6RA1 was increased at 21days; conversely, expression of mannose receptor, a scavenger receptor important in particle clearance, decreased...
February 2017: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/27911926/international-collaboration-patterns-and-effecting-factors-of-emerging-technologies
#13
Xu Bai, Yun Liu
With the globalization of the world economy, international innovation collaboration has taken place all over the world. This study selects three emerging technologies (3D printing, big data and carbon nanotubes and graphene technology) among 20 countries as the research objects, using three patent-based indicators and network relationship analysis to reflect international collaboration patterns. Then we integrate empirical analyses to show effecting factors of international collaboration degrees by using panel data...
2016: PloS One
https://www.readbyqxmd.com/read/27905829/post-traumatic-stress-disorder-dimensions-and-asthma-morbidity-in-world-trade-center-rescue-and-recovery-workers
#14
I Mindlis, E Morales-Raveendran, E Goodman, K Xu, C Vila-Castelar, K Keller, G Crawford, S James, C L Katz, L E Crowley, R E de la Hoz, S Markowitz, J P Wisnivesky
OBJECTIVE: Using data from a cohort of World Trade Center (WTC) rescue and recovery workers with asthma, we assessed whether meeting criteria for post-traumatic stress disorder (PTSD), sub-threshold PTSD, and for specific PTSD symptom dimensions are associated with increased asthma morbidity. METHODS: Participants underwent a Structured Clinical Interview for Diagnostic and Statistical Manual to assess the presence of PTSD following DSM-IV criteria during in-person interviews between December 2013 and April 2015...
December 1, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27898584/prostate-cancer-characteristics-in-the-world-trade-center-cohort-2002-2013
#15
Dana Hashim, Paolo Boffetta, Matthew Galsky, William Oh, Roberto Lucchini, Michael Crane, Benjamin Luft, Jaqueline Moline, Iris Udasin, Denise Harrison, Emanuela Taioli
An increased incidence of prostate cancer was reported in three cohorts of World Trade Center (WTC) respondents. It is uncertain whether this increase is because of WTC-related exposures or enhanced surveillance. Prostate cancer cases (2002-2013) were obtained from the WTC Health Program. Age, race, and Gleason score distribution were compared with New York State Cancer Registry cases from the same time period. Multivariate models were adjusted for age and race. Analyses of clinical characteristics of prostate cancer cases within the cohort were also carried out, adjusting for age, race, and WTC exposure categories...
November 24, 2016: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/27893529/the-role-of-theory-specific-techniques-and-therapeutic-alliance-in-promoting-positive-outcomes-integrative-psychotherapy-for-world-trade-center-responders
#16
Peter Tejas Haugen, Aditi Sinha Werth, Alyce Lauren Foster, Jesse Owen
World Trade Center responders demonstrate high symptom burden, underscoring the importance of refining treatment approaches for this cohort. One method is examining the impact of therapy techniques on outcomes, and the interactions between technique and alliance on outcomes. This study a) examined the interaction of early treatment techniques on integrative psychotherapy outcomes and b) explored whether associations differed at varying levels of alliance. Twenty-nine adult responders diagnosed with partial or full posttraumatic stress disorder received outpatient psychotherapy and completed weekly measures of alliance, technique, and symptom distress...
December 2016: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/27833099/proteomic-characterization-of-the-world-trade-center-dust-activated-mdig-and-c-myc-signaling-circuit-linked-to-multiple-myeloma
#17
Kai Wu, Lingzhi Li, Chitra Thakur, Yongju Lu, Xiangmin Zhang, Zhengping Yi, Fei Chen
Several epidemiological studies suggested an increased incidence rate of multiple myeloma (MM) among first responders and other individuals who exposed to World Trade Center (WTC) dust. In this report, we provided evidence showing that WTC dust is potent in inducing mdig protein and/or mRNA in bronchial epithelial cells, B cells and MM cell lines. An increased mdig expression in MM bone marrow was observed, which is associated with the disease progression and prognosis of the MM patients. Through integrative genomics and proteomics approaches, we further demonstrated that mdig directly interacts with c-myc and JAK1 in MM cell lines, which contributes to hyperactivation of the IL-6-JAK-STAT3 signaling important for the pathogenesis of MM...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27820766/neurologic-evaluations-of-patients-exposed-to-the-world-trade-center-disaster
#18
Mark M Stecker, Huiying Yu, Renee Barlev, Michael Marmor, Marc Wilkenfeld
OBJECTIVE: The aim of this study was to describe the clinical phenotype of a limited group of responders and survivors of the World Trade Center (WTC) disaster who were referred for the evaluation of neuropathic symptoms. METHODS: Sixteen patients with WTC exposure were referred to a neurologist for evaluation. All had a neurologic examination. Most had electromyogram and nerve conduction testing/nerve conduction studies as well as appropriate imaging and blood tests...
November 2016: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27810938/post-9-11-2001-lung-function-trajectories-by-sex-and-race-in-world-trade-center-exposed-new-york-city-emergency-medical-service-workers
#19
Madeline Vossbrinck, Rachel Zeig-Owens, Charles B Hall, Theresa Schwartz, William Moir, Mayris P Webber, Hillel W Cohen, Anna Nolan, Michael D Weiden, Vasilios Christodoulou, Kerry J Kelly, Thomas K Aldrich, David J Prezant
OBJECTIVE: To determine whether lung function trajectories after 9/11/2001 (9/11) differed by sex or race/ethnicity in World Trade Center-exposed Fire Department of the City of New York emergency medical service (EMS) workers. METHOD: Serial cross-sectional study of pulmonary function tests (PFTs) taken between 9/11 and 9/10/2015. We used data from routine PFTs (forced expiratory volume in 1 s (FEV1) and FEV1% predicted), conducted at 12-18 month intervals. FEV1 and FEV1% predicted were assessed over time, stratified by sex, and race/ethnicity...
November 3, 2016: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/27809947/emergency-preparedness-safety-climate-and-other-factors-associated-with-mental-health-outcomes-among-world-trade-center-disaster-evacuees
#20
Martin F Sherman, Robyn R Gershon, Halley E M Riley, Qi Zhi, Lori A Magda, Mark Peyrot
OBJECTIVE: We examined psychological outcomes in a sample of participants who evacuated from the World Trade Center towers on September 11, 2011. This study aimed to identify risk factors for psychological injury that might be amenable to change, thereby reducing adverse impacts associated with emergency high-rise evacuation. METHODS: We used data from a cross-sectional survey conducted 2 years after the attacks to classify 789 evacuees into 3 self-reported psychological outcome categories: long-term psychological disorder diagnosed by a physician, short-term psychological disorder and/or memory problems, and no known psychological disorder...
November 4, 2016: Disaster Medicine and Public Health Preparedness
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