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https://www.readbyqxmd.com/read/29024005/functional-limitations-among-responders-to-the-world-trade-center-attacks-14-years-after-the-disaster-implications-of-chronic-posttraumatic-stress-disorder
#1
Sean A P Clouston, Jack M Guralnik, Roman Kotov, Evelyn J Bromet, Benjamin J Luft
Posttraumatic stress disorder (PTSD) is associated with self-reported difficulties navigating the social and physical world and may also be associated with risk of functional limitations. The Short Physical Performance Battery (SPPB), an objective functional assessment, was administered during monitoring exams between January and December 2015 to a consecutive sample of 1,268 rescue workers, volunteers, and other responders who had aided in response, recovery, and cleanup efforts at the World Trade Center (WTC) in New York after the September 11, 2011 attacks...
October 12, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28972913/cardiometabolic-profiles-of-adolescents-and-young-adults-exposed-to-the-world-trade-center-disaster
#2
Leonardo Trasande, Tony T Koshy, Joseph Gilbert, Lauren K Burdine, Michael Marmor, Xiaoxia Han, Yongzhao Shao, Claude Chemtob, Teresa M Attina, Elaine M Urbina
BACKGROUND AND OBJECTIVE: Few studies have examined the possible cardiometabolic consequences of World Trade Center-related exposures on children who lived and/or attended school near the disaster site. Our objective was to compare cardiometabolic profiles of participants in the World Trade Center Health Registry (WTCHR) with a matched comparison group. METHODS: We evaluated WTCHR enrollees who resided in New York City and were born between September 11, 1993 and September 10, 2001, and a matched comparison group...
September 30, 2017: Environmental Research
https://www.readbyqxmd.com/read/28969127/international-depository-authority-and-its-role-in-microorganism-s-deposition
#3
REVIEW
Abhishek Parashar
After the World Trade Organization's agreement on Trade Related Aspect of Intellectual Property Right, patents have come into major play. Patenting of work related to live organisms that have medical, agricultural and other uses is always a tedious, complicated and controversial job. In view of this an agreement called as Budapest Treaty was passed in 1977 for deposition of microorganisms in culture collection centers for patent purpose. To make a culture collection center an IDA the culture center has to follow rules and regulations made in Budapest Treaty...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28953072/persistent-post-9-11-hearing-problems-among-world-trade-center-health-registry-rescue-and-recovery-workers-2001-to-2007
#4
Cheryl R Stein, David J Lee, Gregory A Flamme, James E Cone
OBJECTIVE: To examine the association between 9/11-related exposures and self-reported hearing problems among 16,579 rescue/recovery workers in the World Trade Center (WTC) Health Registry. METHODS: Using Registry Waves 1 (2003 to 2004) and 2 (2006 to 2007), we modeled the association between two metrics of 9/11-related exposures and hearing difficulties. RESULTS: The prevalence of incident, persistent hearing problems was 4.4%. In a fully adjusted model, workers with higher environmental hazards scores were twice as likely (interquartile range OR 2...
September 25, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28926576/receptor-for-advanced-glycation-end-products-and-world-trade-center-particulate-induced-lung-function-loss-a-case-cohort-study-and-murine-model-of-acute-particulate-exposure
#5
Erin J Caraher, Sophia Kwon, Syed H Haider, George Crowley, Audrey Lee, Minah Ebrahim, Liqun Zhang, Lung-Chi Chen, Terry Gordon, Mengling Liu, David J Prezant, Ann Marie Schmidt, Anna Nolan
World Trade Center-particulate matter(WTC-PM) exposure and metabolic-risk are associated with WTC-Lung Injury(WTC-LI). The receptor for advanced glycation end-products (RAGE) is most highly expressed in the lung, mediates metabolic risk, and single-nucleotide polymorphisms at the AGER-locus predict forced expiratory volume(FEV). Our objectives were to test the hypotheses that RAGE is a biomarker of WTC-LI in the FDNY-cohort and that loss of RAGE in a murine model would protect against acute PM-induced lung disease...
2017: PloS One
https://www.readbyqxmd.com/read/28913914/new-onset-of-asthma-and-job-status-change-among-world-trade-center-responders-and-workers
#6
Hyun Kim, Sherry Baron, Navneet K Baidwan, Adam Schwartz, Jacqueline Moline
BACKGROUND: Despite the high rates, the consequences of new onset asthma among the World Trade Center (WTC) responders in terms of the change in job status have not been studied. METHODS: This study consists of a cohort of 8132 WTC responders out of the total 25 787 responders who held a full-time job at the baseline visit, and participated in at least one follow-up visit. RESULTS: Overall, 34% of the study cohort changed their job status from full-time at a follow-up visit...
September 14, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28890218/serum-perfluoroalkyl-substances-and-cardiometabolic-consequences-in-adolescents-exposed-to-the-world-trade-center-disaster-and-a-matched-comparison-group
#7
Tony T Koshy, Teresa M Attina, Akhgar Ghassabian, Joseph Gilbert, Lauren K Burdine, Michael Marmor, Masato Honda, Dinh Binh Chu, Xiaoxia Han, Yongzhao Shao, Kurunthachalam Kannan, Elaine M Urbina, Leonardo Trasande
BACKGROUND: Large amounts of various chemical contaminants, including perfluoroalkyl substances (PFASs), were released at the time of the World Trade Center (WTC) disaster. Thousands of children who lived and/or attended school near the disaster site were exposed to these substances but few studies have examined the possible consequences related to these exposures. OBJECTIVES: To examine the relationship of PFASs serum levels with cardiometabolic profile in children and adolescents enrolled in the World Trade Center Health Registry (WTCHR) and a matched comparison group...
September 7, 2017: Environment International
https://www.readbyqxmd.com/read/28810960/talk-to-the-hand-u-s-army-biophysical-testing
#8
William R Santee, Adam W Potter, Karl E Friedl
BACKGROUND: Many people are unaware of the science underlying the biophysical properties of Soldier clothing and personal protective equipment, yet there is a well-refined biomedical methodology initiated by Army physiologists in World War II. This involves a methodical progression of systematic material testing technologies, computer modeling, and human testing that enables more efficient development and rapid evaluation of new concepts for Soldier health and performance. Sophisticated manikins that sweat and move are a central part of this testing continuum...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28755626/the-use-of-forensic-dna-analysis-in-humanitarian-forensic-action-the-development-of-a-set-of-international-standards
#9
William H Goodwin
DNA analysis was first applied to the identification of victims of armed conflicts and other situations of violence (ACOSV) in the mid-1990s, starting in South America and the Balkans. Argentina was the first country to establish a genetic database specifically developed to identify disappeared children. Following on from these programs the early 2000s marked major programs, using a largely DNA-led approach, identifying missing persons in the Balkans and following the attack on the World Trade Center in New York...
September 2017: Forensic Science International
https://www.readbyqxmd.com/read/28707852/medicine-and-the-making-of-a-city-spaces-of-pharmacy-and-scholarly-medicine-in-seventeenth-century-stockholm
#10
Hjalmar Fors
This essay takes seventeenth-century Stockholm as its point of departure in discussing the many spaces to which early modern medicine belonged, in particular the court, the cityscape, the site of the pharmacy, and the city’s Collegium Medicum. It shows how scholarly medicine and pharmacy arose along with the city itself. They were a part of the city and of its many interlaced local, European, and global flows and relationships. Thus the essay offers new perspectives on medicine as part of, and a driving force behind, Stockholm’s transition from a medieval town to the capital of an early modern state, as well as the city’s integration into the early modern system of global trade...
September 2016: Isis; An International Review Devoted to the History of Science and its Cultural Influences
https://www.readbyqxmd.com/read/28666154/respiratory-problems-and-anxiety-sensitivity-in-smoking-lapse-among-treatment-seeking-smokers
#11
Michael J Zvolensky, Rubén Rodríguez-Cano, Daniel J Paulus, Roman Kotov, Evelyn Bromet, Adam Gonzalez, Kara Manning, Benjamin J Luft
PURPOSE: The current study examined whether the interaction of lower respiratory symptoms and anxiety sensitivity is related to smoking lapse in the context of smoking cessation. METHOD: Participants were adult daily smokers (N=60) exposed to the World Trade Center (WTC) disaster who were in a smoking cessation treatment program (75.0% male, 50.6years old [SD=9.2], and current smoking rate was 17.6 cigarettes per day (SD=10.6). RESULTS: Results indicated that the interaction between lower respiratory symptoms and anxiety sensitivity was a significant predictor of greater risk for lapse (i...
December 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28654093/an-epigenome-wide-dna-methylation-study-of-ptsd-and-depression-in-world-trade-center-responders
#12
P-F Kuan, M A Waszczuk, R Kotov, C J Marsit, G Guffanti, A Gonzalez, X Yang, K Koenen, E Bromet, B J Luft
Previous epigenome-wide association studies (EWAS) of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) have been inconsistent. This may be due to small sample sizes, and measurement and tissue differences. The current two EWA analyses of 473 World Trade Center responders are the largest to date for both PTSD and MDD. These analyses investigated DNA methylation patterns and biological pathways influenced by differentially methylated genes associated with each disorder. Methylation was profiled on blood samples using Illumina 450 K Beadchip...
June 27, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28644057/the-implementation-of-medical-monitoring-programs-following-potentially-hazardous-exposures-a-medico-legal-perspective
#13
REVIEW
David Vearrier, Michael I Greenberg
CONTEXT: Clinical toxicologists may be called upon to determine the appropriateness of medical monitoring following documented or purported exposures to toxicants in the occupational, environmental, and medical settings. METHODS: We searched the MEDLINE database using the Ovid(®) search engine for the following terms cross-referenced to the MeSH database: ("occupational exposures" OR "environmental exposures") AND ("physiologic monitoring" OR "population surveillance")...
November 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28626847/injury-intense-dust-exposure-and-chronic-disease-among-survivors-of-the-world-trade-center-terrorist-attacks-of-september-11-2001
#14
Howard E Alper, Shengchao Yu, Steven D Stellman, Robert M Brackbill
BACKGROUND: The World Trade Center attack of September 11, 2001 in New York City (9/11) exposed thousands of people to intense concentrations of hazardous materials that have resulted in reports of increased levels of asthma, heart disease, diabetes, and other chronic diseases along with psychological illnesses such as post-traumatic stress disorder (PTSD). Few studies have discriminated between health consequences of immediate (short-term or acute) intense exposures versus chronic residential or workplace exposures...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28626126/conduct-of-occupational-health-during-major-disasters-a-comparison-of-literature-on-occupational-health-issues-in-the-world-trade-center-terrorist-attack-and-the-fukushima-nuclear-power-plant-accident
#15
Hiroyuki Toyoda, Koji Mori
Workers who respond to large-scale disasters can be exposed to health hazards that do not exist in routine work. It is assumed that learning from past cases is effective for preparing for and responding to such problems, but published information is still insufficient. Accordingly, we conducted a literature review about the health issues and occupational health activities at the World Trade Center (WTC) terrorist attack and at the Fukushima Nuclear Power Plant accident to investigate how occupational health activities during disasters should be conducted...
2017: Journal of UOEH
https://www.readbyqxmd.com/read/28622920/post-9-11-sarcoidosis-in-wtc-exposed-firefighters-and-emergency-medical-service-workers
#16
Mayris P Webber, Jennifer Yip, Rachel Zeig-Owens, William Moir, Patompong Ungprasert, Cynthia S Crowson, Charles B Hall, Nadia Jaber, Michael D Weiden, Eric L Matteson, David J Prezant
INTRODUCTION: The World Trade Center (WTC) disaster released a huge quantity and variety of toxicants into the environment. To-date, studies from each of the three major cohorts of WTC-exposed workers have suggested "greater than expected" numbers of post-9/11 cases in some workers. We undertook this study to estimate the incidence of post-9/11 sarcoidosis in ∼13,000 male firefighters and EMS workers enrolled in The Fire Department of the City of New York (FDNY) WTC Health Program; to compare FDNY incidence to rates from unexposed, demographically similar men in the Rochester Epidemiology Project (REP); and, to examine rates by level of WTC exposure...
June 7, 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28586254/hospitalizations-for-asthma-among-adults-exposed-to-the-september-11-2001-world-trade-center-terrorist-attack
#17
Sara A Miller-Archie, Hannah T Jordan, Howard Alper, Juan P Wisnivesky, James E Cone, Stephen M Friedman, Robert M Brackbill
OBJECTIVE: We described the patterns of asthma hospitalization among persons exposed to the 2001 World Trade Center (WTC) attacks, and assessed whether 9/11-related exposures or comorbidities, including posttraumatic stress disorder (PTSD) and gastroesophageal reflux symptoms (GERS), were associated with an increased rate of hospitalization. METHODS: Data for adult enrollees in the WTC Health Registry, a prospective cohort study, with self-reported physician-diagnosed asthma who resided in New York State on 9/11 were linked to administrative hospitalization data to identify asthma hospitalizations during September 11, 2001-December 31, 2010...
June 6, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28572779/differences-in-cortisol-response-to-trauma-activation-in-individuals-with-and-without-comorbid-ptsd-and-depression
#18
Sharon Dekel, Tsachi Ein-Dor, Jeffrey B Rosen, George A Bonanno
Background: Although depression symptoms are often experienced by individuals who develop posttraumatic stress disorder (PTSD) following trauma exposure, little is know about the biological correlates associated with PTSD and depression co-morbidity vs. those associated with PTSD symptoms alone. Methods: Here we examined salivary cortisol responses to trauma activation in a sample of 60 survivors of the World Trade Center attacks on September 11, 2001. Participants recalled the escape from the attacks 7 months post 9/11...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28569707/know-how-in-postwar-business-and-law
#19
Douglas O'Reagan
In the mid-twentieth century, businesses around the world began to see technical know-how as one of the most important assets they could possess. While their exact definitions of know-how varied (usually centering on employees' tacit knowledge; accumulated, minor innovations rather than just patentable inventions; and tailoring to local conditions), the rapidly growing perception that it was invaluable led to widespread know-how licensing. As businesses embraced it, legal scholars and business lawyers during the 1950s through the 1970s scrambled to clarify legal bases for intellectual property protections for know-how...
2017: Technology and Culture
https://www.readbyqxmd.com/read/28446131/the-effectiveness-of-a-monetary-incentive-offer-on-survey-response-rates-and-response-completeness-in-a-longitudinal-study
#20
Shengchao Yu, Howard E Alper, Angela-Maithy Nguyen, Robert M Brackbill, Lennon Turner, Deborah J Walker, Carey B Maslow, Kimberly C Zweig
BACKGROUND: Achieving adequate response rates is an ongoing challenge for longitudinal studies. The World Trade Center Health Registry is a longitudinal health study that periodically surveys a cohort of ~71,000 people exposed to the 9/11 terrorist attacks in New York City. Since Wave 1, the Registry has conducted three follow-up surveys (Waves 2-4) every 3-4 years and utilized various strategies to increase survey participation. A promised monetary incentive was offered for the first time to survey non-respondents in the recent Wave 4 survey, conducted 13-14 years after 9/11...
April 26, 2017: BMC Medical Research Methodology
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