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https://www.readbyqxmd.com/read/29201993/traumatic-exposures-posttraumatic-stress-disorder-and-cognitive-functioning-in-world-trade-center-responders
#1
Sean Clouston, Robert H Pietrzak, Roman Kotov, Marcus Richards, Avron Spiro, Stacey Scott, Yael Deri, Soumyadeep Mukherjee, Candace Stewart, Evelyn Bromet, Benjamin J Luft
Introduction: This study examined whether World Trade Center (WTC)-related exposures and posttraumatic stress disorder (PTSD) were associated with cognitive function and whether WTC responders' cognition differed from normative data. Methods: A computer-assisted neuropsychological battery was administered to a prospective cohort study of 1193 WTC responders with no history of stroke or WTC-related head injuries. Data were linked to information collected prospectively since 2002...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29199867/relevance-of-global-health-security-to-the-us-export-economy
#2
Cynthia H Cassell, Zoe Bambery, Kakoli Roy, Martin I Meltzer, Zara Ahmed, Rebecca L Payne, Rebecca E Bunnell
To reduce the health security risk and impact of outbreaks around the world, the US Centers for Disease Control and Prevention and its partners are building capabilities to prevent, detect, and contain outbreaks in 49 global health security priority countries. We examine the extent of economic vulnerability to the US export economy posed by trade disruptions in these 49 countries. Using 2015 US Department of Commerce data, we assessed the value of US exports and the number of US jobs supported by those exports...
December 4, 2017: Health Security
https://www.readbyqxmd.com/read/29165779/resilience-to-post-traumatic-stress-among-world-trade-center-survivors-a-mixed-methods-study
#3
Lisa M Gargano, Sindhushree Hosakote, Qi Zhi, Kristine A Qureshi, Robyn R Gershon
The purpose of this study was to identify individual characteristics, behaviors, and psychosocial factors associated with symptoms of post-traumatic stress disorder (PTSD) among World Trade Center (WTC) disaster evacuation survivors. The study utilized a mixed-method design. In-depth interviews were conducted using a prepared script. PTSD was assessed using the PTSD checklist-civilian (PCL-C; a score ≥ 50 indicates probable PTSD). Thematic analysis was conducted to identify factors associated with PTSD. A purposive sample of 29 WTC evacuees was recruited using a multimodal recruitment strategy...
September 2017: Journal of Emergency Management: JEM
https://www.readbyqxmd.com/read/29148090/assessment-of-cumulative-health-risk-in-the-world-trade-center-general-responder-cohort
#4
Ghalib A Bello, Susan L Teitelbaum, Roberto G Lucchini, Christopher R Dasaro, Moshe Shapiro, Julia R Kaplan, Michael A Crane, Denise J Harrison, Benjamin J Luft, Jacqueline M Moline, Iris G Udasin, Andrew C Todd
BACKGROUND: Multiple comorbidities have been reported among rescue/recovery workers responding to the 9/11/2001 WTC disaster. In this study, we developed an index that quantifies the cumulative physiological burden of comorbidities and predicts life expectancy in this cohort. METHODS: A machine learning approach (gradient boosting) was used to model the relationship between mortality and several clinical parameters (laboratory test results, blood pressure, pulmonary function measures)...
November 17, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29131407/posttraumatic-stress-disorder-gender-and-risk-factors-world-trade-center-tower-survivors-10-to-11-years-after-the-september-11-2001-attacks
#5
Rosemarie M Bowler, Shane W Adams, Vihra V Gocheva, Jiehui Li, Donna Mergler, Robert Brackbill, James E Cone
Ten to eleven years after the September 11, 2001 terrorist attacks, probable posttraumatic stress disorder (PTSD) was evaluated in 1,755 World Trade Center (WTC) evacuees based on data from the WTC Health Registry. Characteristics of men and women were compared and factors associated with PTSD symptom severity were examined using the PTSD Checklist (PCL). Compared with men (n = 1,015, 57.8%), women (n = 740, 42.2%) were younger and of lower socioeconomic status. Ten to eleven years after September 11, 2001, 13...
November 13, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/29124117/proton-pump-inhibitors-and-the-risk-of-severe-cognitive-impairment-the%C3%A2-role-of-posttraumatic-stress-disorder
#6
Sean A P Clouston, Oren Shapira, Roman Kotov, Lan Lei, Monika Waszczuk, Evelyn J Bromet, Benjamin J Luft
Introduction: Proton pump inhibitors (PPIs), a common treatment for gastroesophageal reflux disease (GERD), were recently associated with increased risk of dementia. However, severe or chronic stress including, for example, posttraumatic stress disorder (PTSD) was not accounted for. This study examined whether PPI use was associated with severe cognitive impairment (SCI) and whether PTSD explained this association in a cohort of World Trade Center (WTC) responders. Method: A prospective cohort study of 3779 WTC responders attending a university-based monitoring and treatment program...
November 2017: Alzheimer's & Dementia: Translational Research & Clinical Interventions
https://www.readbyqxmd.com/read/29099614/blood-leukocyte-concentrations-fev1-decline-and-airflow-limitation-a-15-year-longitudinal-study-of-wtc-exposed-firefighters
#7
Rachel Zeig-Owens, Ankura Singh, Thomas K Aldrich, Charles B Hall, Theresa Schwartz, Mayris P Webber, Hillel W Cohen, Kerry J Kelly, Anna Nolan, David J Prezant, Michael D Weiden
RATIONALE: Rescue/recovery work at the World Trade Center (WTC) disaster site caused a proximate decline in lung function in Fire Department of the City of New York (FDNY) firefighters. A subset of this cohort experienced an accelerated rate of lung function decline over 15 years of post-9/11 follow-up. OBJECTIVES: To determine if post-exposure inflammatory cell concentrations are biomarkers for subsequent forced expiratory volume (FEV1) decline and incident airflow limitation...
November 3, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29069108/the-prevalence-characteristics-and-correlates-of-anger-among-survivors-of-the-9-11-world-trade-center-attacks
#8
Duy Vu Tran, Carol S North
BACKGROUND: Anger is a prominent and common emotion in postdisaster settings. However, there has been little systematic investigation of the association of anger with psychopathology or other individual characteristics in disaster survivors. This study examined anger responses reported by disaster survivors and correlates of that anger. METHODS: Structured interviews were conducted with a volunteer sample of 379 employees of 7 agencies that were highly affected by the September 11, 2001, terrorist attacks on the World Trade Center in New York City...
November 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/29066387/clinical-course-of-sarcoidosis-in-world-trade-center-exposed-firefighters
#9
Kerry M Hena, Jennifer Yip, Nadia Jaber, David Goldfarb, Kelly Fullam, Krystal Cleven, William Moir, Rachel Zeig-Owens, Mayris P Webber, Daniel M Spevack, Marc A Judson, Lisa Maier, Andrew Krumerman, Anthony Aizer, Simon D Spivack, Jessica Berman, Thomas K Aldrich, David J Prezant
BACKGROUND: Sarcoidosis is believed to represent a genetically primed, abnormal immune response to an antigen exposure or inflammatory trigger, with both genetic and environmental factors playing a role in disease onset and phenotypic expression. In a population of firefighters with post-World Trade Center (WTC) 9/11/2001 (9/11) sarcoidosis, we have a unique opportunity to describe the clinical course of incident sarcoidosis during the 15 years' postexposure and, on average, 8 years following diagnosis...
October 21, 2017: Chest
https://www.readbyqxmd.com/read/29024005/functional-limitations-among-responders-to-the-world-trade-center-attacks-14-years-after-the-disaster-implications-of-chronic-posttraumatic-stress-disorder
#10
Sean A P Clouston, Jack M Guralnik, Roman Kotov, Evelyn J Bromet, Benjamin J Luft
Posttraumatic stress disorder (PTSD) is associated with self-reported difficulties navigating the social and physical world and may also be associated with risk of functional limitations. The Short Physical Performance Battery (SPPB), an objective functional assessment, was administered during monitoring exams between January and December 2015 to a consecutive sample of 1,268 rescue workers, volunteers, and other responders who had aided in response, recovery, and cleanup efforts at the World Trade Center (WTC) in New York after the September 11, 2011 attacks...
October 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28972913/cardiometabolic-profiles-of-adolescents-and-young-adults-exposed-to-the-world-trade-center-disaster
#11
Leonardo Trasande, Tony T Koshy, Joseph Gilbert, Lauren K Burdine, Michael Marmor, Xiaoxia Han, Yongzhao Shao, Claude Chemtob, Teresa M Attina, Elaine M Urbina
BACKGROUND AND OBJECTIVE: Few studies have examined the possible cardiometabolic consequences of World Trade Center-related exposures on children who lived and/or attended school near the disaster site. Our objective was to compare cardiometabolic profiles of participants in the World Trade Center Health Registry (WTCHR) with a matched comparison group. METHODS: We evaluated WTCHR enrollees who resided in New York City and were born between September 11, 1993 and September 10, 2001, and a matched comparison group...
September 30, 2017: Environmental Research
https://www.readbyqxmd.com/read/28969127/international-depository-authority-and-its-role-in-microorganism-s-deposition
#12
REVIEW
Abhishek Parashar
After the World Trade Organization's agreement on Trade Related Aspect of Intellectual Property Right, patents have come into major play. Patenting of work related to live organisms that have medical, agricultural and other uses is always a tedious, complicated and controversial job. In view of this an agreement called as Budapest Treaty was passed in 1977 for deposition of microorganisms in culture collection centers for patent purpose. To make a culture collection center an IDA the culture center has to follow rules and regulations made in Budapest Treaty...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28953072/persistent-post-9-11-hearing-problems-among-world-trade-center-health-registry-rescue-and-recovery-workers-2001-to-2007
#13
Cheryl R Stein, David J Lee, Gregory A Flamme, James E Cone
OBJECTIVE: To examine the association between 9/11-related exposures and self-reported hearing problems among 16,579 rescue/recovery workers in the World Trade Center (WTC) Health Registry. METHODS: Using Registry Waves 1 (2003 to 2004) and 2 (2006 to 2007), we modeled the association between two metrics of 9/11-related exposures and hearing difficulties. RESULTS: The prevalence of incident, persistent hearing problems was 4.4%. In a fully adjusted model, workers with higher environmental hazards scores were twice as likely (interquartile range OR 2...
September 25, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28926576/receptor-for-advanced-glycation-end-products-and-world-trade-center-particulate-induced-lung-function-loss-a-case-cohort-study-and-murine-model-of-acute-particulate-exposure
#14
Erin J Caraher, Sophia Kwon, Syed H Haider, George Crowley, Audrey Lee, Minah Ebrahim, Liqun Zhang, Lung-Chi Chen, Terry Gordon, Mengling Liu, David J Prezant, Ann Marie Schmidt, Anna Nolan
World Trade Center-particulate matter(WTC-PM) exposure and metabolic-risk are associated with WTC-Lung Injury(WTC-LI). The receptor for advanced glycation end-products (RAGE) is most highly expressed in the lung, mediates metabolic risk, and single-nucleotide polymorphisms at the AGER-locus predict forced expiratory volume(FEV). Our objectives were to test the hypotheses that RAGE is a biomarker of WTC-LI in the FDNY-cohort and that loss of RAGE in a murine model would protect against acute PM-induced lung disease...
2017: PloS One
https://www.readbyqxmd.com/read/28913914/new-onset-of-asthma-and-job-status-change-among-world-trade-center-responders-and-workers
#15
Hyun Kim, Sherry Baron, Navneet K Baidwan, Adam Schwartz, Jacqueline Moline
BACKGROUND: Despite the high rates, the consequences of new onset asthma among the World Trade Center (WTC) responders in terms of the change in job status have not been studied. METHODS: This study consists of a cohort of 8132 WTC responders out of the total 25 787 responders who held a full-time job at the baseline visit, and participated in at least one follow-up visit. RESULTS: Overall, 34% of the study cohort changed their job status from full-time at a follow-up visit...
September 14, 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28890218/serum-perfluoroalkyl-substances-and-cardiometabolic-consequences-in-adolescents-exposed-to-the-world-trade-center-disaster-and-a-matched-comparison-group
#16
Tony T Koshy, Teresa M Attina, Akhgar Ghassabian, Joseph Gilbert, Lauren K Burdine, Michael Marmor, Masato Honda, Dinh Binh Chu, Xiaoxia Han, Yongzhao Shao, Kurunthachalam Kannan, Elaine M Urbina, Leonardo Trasande
BACKGROUND: Large amounts of various chemical contaminants, including perfluoroalkyl substances (PFASs), were released at the time of the World Trade Center (WTC) disaster. Thousands of children who lived and/or attended school near the disaster site were exposed to these substances but few studies have examined the possible consequences related to these exposures. OBJECTIVES: To examine the relationship of PFASs serum levels with cardiometabolic profile in children and adolescents enrolled in the World Trade Center Health Registry (WTCHR) and a matched comparison group...
December 2017: Environment International
https://www.readbyqxmd.com/read/28810960/talk-to-the-hand-u-s-army-biophysical-testing
#17
William R Santee, Adam W Potter, Karl E Friedl
BACKGROUND: Many people are unaware of the science underlying the biophysical properties of Soldier clothing and personal protective equipment, yet there is a well-refined biomedical methodology initiated by Army physiologists in World War II. This involves a methodical progression of systematic material testing technologies, computer modeling, and human testing that enables more efficient development and rapid evaluation of new concepts for Soldier health and performance. Sophisticated manikins that sweat and move are a central part of this testing continuum...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28755626/the-use-of-forensic-dna-analysis-in-humanitarian-forensic-action-the-development-of-a-set-of-international-standards
#18
William H Goodwin
DNA analysis was first applied to the identification of victims of armed conflicts and other situations of violence (ACOSV) in the mid-1990s, starting in South America and the Balkans. Argentina was the first country to establish a genetic database specifically developed to identify disappeared children. Following on from these programs the early 2000s marked major programs, using a largely DNA-led approach, identifying missing persons in the Balkans and following the attack on the World Trade Center in New York...
September 2017: Forensic Science International
https://www.readbyqxmd.com/read/28707852/medicine-and-the-making-of-a-city-spaces-of-pharmacy-and-scholarly-medicine-in-seventeenth-century-stockholm
#19
Hjalmar Fors
This essay takes seventeenth-century Stockholm as its point of departure in discussing the many spaces to which early modern medicine belonged, in particular the court, the cityscape, the site of the pharmacy, and the city’s Collegium Medicum. It shows how scholarly medicine and pharmacy arose along with the city itself. They were a part of the city and of its many interlaced local, European, and global flows and relationships. Thus the essay offers new perspectives on medicine as part of, and a driving force behind, Stockholm’s transition from a medieval town to the capital of an early modern state, as well as the city’s integration into the early modern system of global trade...
September 2016: Isis; An International Review Devoted to the History of Science and its Cultural Influences
https://www.readbyqxmd.com/read/28666154/respiratory-problems-and-anxiety-sensitivity-in-smoking-lapse-among-treatment-seeking-smokers
#20
Michael J Zvolensky, Rubén Rodríguez-Cano, Daniel J Paulus, Roman Kotov, Evelyn Bromet, Adam Gonzalez, Kara Manning, Benjamin J Luft
PURPOSE: The current study examined whether the interaction of lower respiratory symptoms and anxiety sensitivity is related to smoking lapse in the context of smoking cessation. METHOD: Participants were adult daily smokers (N=60) exposed to the World Trade Center (WTC) disaster who were in a smoking cessation treatment program (75.0% male, 50.6years old [SD=9.2], and current smoking rate was 17.6 cigarettes per day (SD=10.6). RESULTS: Results indicated that the interaction between lower respiratory symptoms and anxiety sensitivity was a significant predictor of greater risk for lapse (i...
December 2017: Addictive Behaviors
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