Jimmy C Yang, Nitish M Harid, Fábio A Nascimento, Vasileios Kokkinos, Abigail Shaughnessy, Alice D Lam, M Brandon Westover, Thabele M Leslie-Mazwi, Leigh R Hochberg, Eric S Rosenthal, Andrew J Cole, Robert M Richardson, Sydney S Cash
No clear evidence-based treatment paradigm currently exists for refractory and super-refractory status epilepticus, which can result in significant mortality and morbidity. While patients are typically treated with antiepileptic drugs and anesthetics, neurosurgical neuromodulation techniques can also be considered. We present a novel case in which responsive neurostimulation was used to effectively treat a patient who had developed super-refractory status epilepticus, later consistent with epilepsia partialis continua, that was refractory to antiepileptic drugs, immunomodulatory therapies, and transcranial magnetic stimulation...
June 2021: Annals of Clinical and Translational Neurology