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https://www.readbyqxmd.com/read/28101023/pyoderma-gangrenosum-and-erythema-nodosum-revealing-takayasu-s-arteritis
#1
Jonas Loetscher, Susanna Fistarol, Ulrich A Walker
We report a Caucasian female who presented with simultaneous erythema nodosum and pyoderma gangrenosum due to underlying Takayasu's arteritis. Takayasu's arteritis is a chronic large vessel vasculitis of unknown cause. The disease has a worldwide distribution but is most commonly seen in Asian populations. There is a strong predilection for young females. The clinical presentation is variable, but mostly derives from stenosis or occlusion of affected arteries, resulting in claudication and ischemia. Skin manifestations are observed in up to 28% of patients with Takayasu's arteritis, with erythema nodosum reported more frequently in Caucasians...
September 2016: Case Reports in Dermatology
https://www.readbyqxmd.com/read/28099607/a-single-black-ulcer-in-a-child-with-acute-lymphocytic-leukemia
#2
Michelangelo Vestita, Angela Filoni, Nicola Santoro, Gianpaolo Arcamone, Domenico Bonamonte
Ecthyma gangrenosum is an uncommon dermatological manifestation characterized by round, indurated ulcers with a central necrotic black eschar and surrounding erythema. This report describes the case of a 5-year-old girl, affected by acute lymphocytic leukemia, presenting with a black eschar on her right thigh. Such lesions should always be correctly identified to avoid potentially fatal bacteraemia. Furthermore, because of its similar clinical presentation, cutaneous anthrax must be ruled out.
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28096323/pyoderma-gangrenosum-following-complex-reconstruction-of-a-large-scale-lower-limb-defect-by-combined-parascapular-and-latissimus-dorsi-flap
#3
Tomke Cordts, Amir K Bigdeli, Leila Harhaus, Christoph Hirche, Thomas Kremer, Ulrich Kneser, Volker J Schmidt
A female patient with a critical soft tissue defect after elective knee replacement surgery was transferred to our department for reconstruction. As wounds were rapidly progressing, necrotizing fasciitis was initially suspected but eventually ruled out by histopathological analysis. A 50 × 15 cm defect was then reconstructed by means of a combined Parascapular and latissimus dorsi flap before, a couple days later, the patient developed tender pustules and ulcers involving the flap as well as the donor site...
January 17, 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28095714/disease-related-and-drug-induced-skin-manifestations-in-inflammatory-bowel-disease
#4
Pieter Hindryckx, Gregor Novak, Antonio Costanzo, Silvio Danese
Skin manifestations are common in patients with inflammatory bowel diseases (IBD) and can be part of a concomitant illness with a shared genetic background, an extra-intestinal manifestation of the disease, or a drug side-effect. Areas covered: We provide a practical overview of the epidemiology, pathogenesis, diagnosis, therapeutic approach and prognosis of the most frequent disease-related and drug-induced cutaneous manifestations in IBD, illustrated by cases encountered in our clinical practice. Among the most frequently encountered IBD-related lesions are erythema nodosum, pyoderma gangrenosum and Sweet's syndrome...
January 17, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28094164/disorders-characterized-by-predominant-or-exclusive-dermal-inflammation
#5
Mark R Wick
Some cutaneous inflammatory disorders are typified by a predominant or exclusive localization in the dermis. They can be further subdivided by the principal cell types into lymphocytic, neutrophilic, and eosinophilic infiltrates, and mixtures of them are also seen in a proportion of cases. This review considers such conditions. Included among the lymphoid lesions are viral exanthems, pigmented purpuras, gyrate erythemas, polymorphous light eruption, lupus tumidus, and cutaneous lymphoid hyperplasia. Neutrophilic infiltrates are represented by infections, Sweet syndrome, pyoderma gangrenosum, and hidradenitis suppurativa, as well as a group of so-called "autoinflammatory" dermatitides comprising polymorphonuclear leukocytes...
December 14, 2016: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/28079790/ecthyma-gangrenosum-a-skin-manifestation-of-pseudomonas-aeruginosa-sepsis-in-a-previously-healthy-child-a-case-report
#6
Stephanie Biscaye, Diane Demonchy, Mickael Afanetti, Audrey Dupont, Herve Haas, Antoine Tran
RATIONALE: Ecthyma gangrenosum (Eg) is a necrotic lesion that is mostly seen in immunocompromised patients. It reflects a severe sepsis, possibly caused by Pseudomonas aeruginosa (Pa). PATIENT CONCERNS: A healthy 3-year-old girl admitted to the Pediatric Emergency Department presented a sepsis-associated purpura with neurological and respiratory distress. INTERVENTIONS: An empiric antibiotherapy (anti-meningococcal) was prescribed. DIAGNOSES: Forty-eight hours after admission, blood and wound cultures were positive for Pa...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28052953/ecthyma-gangrenosum-in-a-case-of-acute-lymphoblastic-lymphoma
#7
Kundan Mishra, Uday Yanamandra, Gaurav Prakash, Pankaj Malhotra
No abstract text is available yet for this article.
January 4, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28012329/total-hip-arthroplasty-for-femoral-neck-fracture-with-pyoderma-gangrenosum-patient-a-case-report
#8
Guo Rong She, Jun Yuan Chen, Zi Qi Zhou, Zhen Gang Zha, Ning Liu
INTRODUCTION: Pyoderma gangrenosum is a rare inflammatory aseptic, ulcerative neutrophilic dermatosis which manifest as skin recurrent, painful ulcers. PRESENTATION OF CASE: A 65-year-old man with pyoderma gangrenosum underwent left total hip arthroplasty because of femoral neck fractures. Glucocorticoid, antibiotic, anticoagulant drug, etc. were given in perioperative period. Complication of pyoderma gangrenosum was prevented successfully in perioperative period...
December 9, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28003907/multiple-pyoderma-gangrenosum-ulcers-associated-with-cocaine-abuse
#9
Ricardo Ruiz-Villaverde, Daniel Sánchez-Cano
No abstract text is available yet for this article.
November 2016: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/27990392/primary-cutaneous-anaplastic-large-cell-lymphoma-masquerading-as-large-pyogenic-granuloma
#10
Anupama Bains, Deepak Vedant, Vinay Shanker, G R Tegta
Primary cutaneous anaplastic large cell lymphoma (pcALCL) forms 9% of the cutaneous T-cell lymphomas. It usually presents as solitary reddish brown ulcerating nodule or indurated plaque. Sometimes, it mimics other dermatological diseases such as eczema, pyoderma gangrenosum, pyogenic granuloma, morphea, and squamous cell carcinoma. Our case presented with large pyogenic granuloma like lesion with regional lymphadenopathy. Since pcALCL is rare, one can misdiagnose such cases and therefore high index of suspicion is necessary...
November 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27975008/successful-treatment-of-pyoderma-gangrenosum-after-augmentation-mastopexy-using-vacuum-therapy
#11
Julio Alberto Soncini, Alessandra Grassi Salles, Juvenal Antonio Frizzo Neto, Rolf Gemperli
BACKGROUND: Pyoderma gangrenosum (PG) is a rare, severe, destructive neutrophilic dermatosis characterized by a progressive, necrotizing process after skin injury. Its cause is still unknown, and diagnosis represents a challenge when ulcers are seen after surgery. Bacterial infection is not found in the wounds. Patients exhibit "pathergy" with the appearance of new lesions after local trauma such as surgical procedures, debridements, and wound care, suggesting altered inflammatory response...
November 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27943240/autoinflammation-in-pyoderma-gangrenosum-and-its-syndromic-form-pash
#12
A Marzano, G Damiani, I Ceccherini, E Berti, M Gattorno, M Cugno
BACKGROUND: Pyoderma gangrenosum (PG) is a rare skin disease characterized clinically by ulcers with undermined borders, and histologically by neutrophil-rich infitrates. PG may occur alone, in syndromic forms or associated with systemic diseases as inflammatory bowel diseases and hematological or rheumatological disorders. OBJECTIVES: Although some autoinflammatory diseases present with PG, to date, a specific genetic background related to autoinflammation has not been proven for PG...
December 10, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27938245/post-surgical-pyoderma-gangrenosum-in-flap-surgery-diagnostic-clues-and-treatment-recommendations
#13
N S J J Dhooghe, S Oieni, P Peeters, S D'Arpa, N A Roche
BACKGROUND: Post Surgical Pyoderma Gangrenosum (PSPG) is a neutrophilic dermatosis causing aseptic necrotic ulcerations within surgical sites. It is often misdiagnosed as infection or ischemia and worsened by the inappropriate treatment. Therefore diagnostic clues must be identified and awareness for PSPG raised. METHODS: We present two cases of PSPG after flap surgery and a review of the literature. RESULTS: Seventeen cases of PSPG after flap surgery were found...
December 9, 2016: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/27916349/pediatric-pyoderma-gangrenosum-is-it-just-big-wounds-on-little-adults
#14
Tahereh Soleimani, Sarah E Sasor, Leigh Spera, Barry E Eppley, Juan Socas, Michael W Chu, Sunil S Tholpady
BACKGROUND: Pyoderma gangrenosum (PG) is an uncommon, ulcerative, cutaneous condition, often caused by surgical trauma that can masquerade as a pyogenic disease process requiring debridement and antibiotics. Treatment is, however, medical, with delay leading to significant morbidity. In addition, medical workup for coincident disorders has been suggested. The purpose of this study was to test the hypothesis that pediatric PG has differing disease associations and therefore requires a differing medical workup...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27904188/cutaneous-manifestations-of-multiple-myeloma
#15
Binodini Behera, Monali Pattnaik, Bharti Sahu, Prasenjeet Mohanty, Swapna Jena, Liza Mohapatra
Multiple myeloma (MM) is a proliferative disorder of plasma cells which produce abnormal immunoglobulin proteins. Skin involvement is rarely found in this disorder. They are either specific or nonspecific lesions. We report four such interesting patients who presented to us initially with common dermatoses such as leukocytoclastic vasculitis, pyoderma gangrenosum, and vesiculobullous disorders and were subsequently diagnosed to have MM. There were no skeletal involvements or renal function abnormality at the time of presentation...
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27900062/pyoderma-gangrenosum-with-spleen-involvement-review-of-the-literature-and-case-report
#16
Rodica Cosgarea, Simona Corina Senilă, Radu Badea, Loredana Ungureanu
BACKGROUND: Pyoderma gangrenosum is a rare, ulcerative, destructive, non-infectious dermatologic disease and it is one clinical entity within the spectrum of neutrophilic dermatoses. Visceral involvement, manifesting as sterile neutrophilic infiltrates in sites other than skin and, is infrequent. Splenic involvement is very rare. MAIN OBSERVATIONS: We present a case of a 58-year-old woman with pyoderma gangrenosum with spleen involvement and review all reports of similar cases...
November 13, 2016: Journal of Dermatological Case Reports
https://www.readbyqxmd.com/read/27897446/life-threatening-rituximab-induced-pyoderma-gangrenosum-successfully-treated-with-intravenous-immunoglobulin
#17
J Vikse, A Rygh, K Kaisen, R Omdal
No abstract text is available yet for this article.
November 29, 2016: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/27893584/facial-pyoderma-gangrenosum-presenting-with-cranial-nerve-vii-palsy-and-cicatricial-ectropion
#18
Natalie Homer, Suzanne K Freitag
No abstract text is available yet for this article.
November 23, 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27893467/bullous-pyoderma-gangrenosum-with-subungual-involvement-associated-with-ulcerative-colitis
#19
Ezgi Aktaş Karabay, Asl Aksu Cerman, İlknur Kvanc Altunay, Özben Yalçn
Pyoderma gangrenosum (PG) is a rare inflammatory and ulcerative skin disease of unknown etiology characterized by neutrophilic infiltration of the dermis, mainly affecting the lower extremities. Bullous PG is a rare variant of this disease, usually associated with hematologic disorders. Here, we report a case of pathergy-positive bullous PG with subungual involvement associated with ulcerative colitis.
November 22, 2016: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/27876606/devastating-peristomal-pyoderma-gangrenosum-challenges%C3%A2-in%C3%A2-diagnosis-and-management
#20
James W T Toh, Ian Whiteley
No abstract text is available yet for this article.
November 19, 2016: Clinical Gastroenterology and Hepatology
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