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https://www.readbyqxmd.com/read/29223960/systematic-reviews-of-point-of-care-tests-for-the-diagnosis-of-urogenital-chlamydia-trachomatis-infections
#1
REVIEW
Helen Kelly, Cordelia E M Coltart, Nitika Pant Pai, Jeffrey D Klausner, Magnus Unemo, Igor Toskin, Rosanna W Peeling
BACKGROUND: WHO estimates that 131 million new cases of urogenital Chlamydia trachomatis (CT) infections occur globally every year. Most infections are asymptomatic. Untreated infection in women can lead to severe complications. Screening and treatment of at-risk populations is a priority for prevention and control. OBJECTIVES: To summarise systematic reviews of the performance characteristics of commercially available point-of-care tests (POCT) for screening and diagnosis of urogenital CT infection...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29223938/-prevalence-of-anti-toxoplasma-gondii-antibodies-in-blood-donors-in-buenos-aires-city-from-1967-to-2017
#2
Federico J Kaufer, Liliana A Carral, Matías T Messina, María Vanessa Schneider, Miriam Méndez, Lourdes Herrera, Cristina B Freuler, Ricardo A Durlach
A prevalence study of antibodies anti Toxoplasma gondii in voluntary blood donors who attended the hemotherapy service at the Hospital Alemán during the first four months of the years 1997, 2007 and 2017 was carried out and the results were compared to the study carried out in 1967. The sera where processed with the Sabin Feldman Dye Test. The global average seroprevalence in 1967 was 67.0% (CI95%, 64.4%-69.6%); in 1997, 35.0% (CI95%, 33.3%-38.3%); in 2007, 31.9% (CI95%, 29.6%-34.2%) and in 2017, 21.2% (CI95%, 19...
2017: Medicina
https://www.readbyqxmd.com/read/29223659/complications-in-the-treatment-of-mandibular-condylar-fractures-surgical-versus-conservative-treatment
#3
REVIEW
Iván García-Guerrero, Juan M Ramírez, Rafael Gómez de Diego, José M Martínez-González, María S Poblador, José L Lancho
OBJECTIVES: In the present article, we aim to review the main intra- and post-operative complications associated with two different therapeutic approaches for treating mandibular condylar fractures: conservative (CTR) and surgical treatment (ORIF, Open Reduction and Internal Fixation). MATERIAL AND METHODS: We have carried out a retrospective, meta-analytic, observational study using literature review, covering the period between 2000- September 2017. The data obtained were processed using statistical software SPSS v...
December 6, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29222660/testing-the-role-of-fiscal-policy-in-the-environmental-degradation-the-case-of-turkey
#4
Salih Katircioglu, Setareh Katircioglu
This study introduces a new research topic that investigates the relationship between fiscal development and carbon emissions in Turkey through testing Environmental Kuznets Curve (EKC) hypothesis. Annual data covering the period, 1960-2013, has been used and in addition to gross domestic product and energy consumption, fiscal policy variables have been regressed on the level of carbon emissions in Turkey. Results reveal that fiscal policies and carbon emissions are in long-term equilibrium relationship in Turkey; carbon dioxide emission level converges towards long-term paths as contributed by fiscal policy...
December 8, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29221011/profile-reconstruction-method-adopting-parameterized-re-projection-errors-of-laser-lines-generated-from-bi-cuboid-references
#5
Guan Xu, Jing Yuan, Xiaotao Li, Jian Su
A flexible reconstruction method, which is based on the line re-projection errors of the laser plane, is presented for the profile recovery. The bi-cuboid references are designed to cover the large view-field of the camera. The local intrinsic and extrinsic parameter matrices of the camera are initially contributed by the RQ decomposition. Then the balance model is demonstrated to obtain the global parameter matrices in view of the refined projection in the camera coordinate system. The flexible laser plane is solved by the Plücker matrices of the projection laser lines that are generated from the homographies of the cubical references and the global parameter matrices...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29220777/scenario-modelling-of-land-use-land-cover-changes-in-munessa-shashemene-landscape-of-the-ethiopian-highlands
#6
Mengistie Kindu, Thomas Schneider, Martin Döllerer, Demel Teketay, Thomas Knoke
Models under a set of scenarios are used to simulate and improve our understanding of land use/land cover (LULC) changes, which is central for sustainable management of a given natural resource. In this study, we simulated and examined the possible future LULC patterns and changes in Munessa-Shashemene landscape of the Ethiopian highlands covering four decades (2012-2050) using a spatially explicit GIS-based model. Both primary and secondary sources were utilized to identify relevant explanatory variables (drivers) and LULC datasets for the model...
December 5, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29219910/the-appraisal-of-nursing-practice-instrument-development-and-initial-testing
#7
Heather Becker, Marty Meraviglia, Jin EunJin Seo, Chipo Ndlovu, Lois Kimmel, Toni Rowin
OBJECTIVE: We describe the development of the Appraisal of Nursing Practice (ANP) and present initial psychometric data. BACKGROUND: Although measures of new nurses' confidence in clinical practice exist, psychometrically sound observational tools that assess a broad range of nursing competencies are needed. METHODS: Based on the Quality and Safety Education for Nurses competencies, the 37-item ANP covers person-centered care, teamwork and collaboration, evidence-based practice/quality improvement, safety, informatics, professionalism, and overall satisfaction (with the new nurse's functioning)...
January 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29219629/pharmacotherapy-options-for-managing-chemotherapy-induced-peripheral-neurotoxicity
#8
Guido Cavaletti, Paola Marmiroli
Prevention and treatment of chemotherapy-induced peripheral neurotoxicity (CIPN) are clinically-relevant unmet needs. Despite extensive efforts at the preclinical and clinical levels, no effective pharmacological interventions are available, and this unsatisfactory situation reflects a combination of methodological issues and a lack of effectiveness of the tested drugs. Areas covered: This non-systematic, but unbiased review is based on published papers available in PubMed and screened using the broad search string [chemotherapy (and) neuropathy (and) treatment] to analyze the reported data...
December 8, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29218662/laparoscopic-removal-of-retroperitoneal-tumor-with-maneuver-of-hanging-inferior-vena-cava
#9
Sungho Kim, Ho-Seong Han, YoungRok Choi, Yoo-Seok Yoon, Jai Young Cho
BACKGROUND: Laparoscopic resection of retroperitoneal mass is challenging because of its location close to major vessels and a limited range of laparoscopic instruments [1-3]. We report a case of a huge retroperitoneal paraganglioma that was successfully excised laparoscopically using maneuver of hanging IVC METHOD: A 67-year-old female had abdominal mass detected during routine check-up. She had no symptoms associated mass. Hematologic, biochemical investigations, and hormone tests reveal normal results...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29218030/in-situ-antibacterial-activity-of-essential-oils-with-and-without-alcohol-on-oral-biofilm-a-randomized-clinical-trial
#10
Victor Quintas, Isabel Prada-López, María J Carreira, David Suárez-Quintanilla, Carlos Balsa-Castro, Inmaculada Tomás
Currently, there is little evidence on the in situ antibacterial activity of essential oils (EO) without alcohol. This study aimed to evaluate in situ the substantivity and antiplaque effect on the plaque-like biofilm (PL-biofilm) of two solutions, a traditional formulation that contains EO with alcohol (T-EO) and an alcohol-free formulation of EO (Af-EO). Eighteen healthy adults performed a single mouthwash of: T-EO, Af-EO, and sterile water (WATER) after wearing an individualized disk-holding splint for 2 days...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29217030/perforated-punctal-plugs-with-adjuvant-use-of-mitomycin-c-in-management-of-acquired-external-punctal-stenosis-grades-0-and-1
#11
Ayman S Abd El Ghafar, Amr M El-Kannishy, Mohamed M Elwan, Dalia Sabry, Hanem M Kishk, Eman M Elhefney
OBJECTIVE: To evaluate the use of perforated punctal plugs with adjuvant application of mitomycin-C in the management of acquired external punctal stenosis grades 0 and 1. METHODS: This is a prospective interventional case series including 30 eyes of 30 patients with acquired external punctal stenosis of the lower punctum of grades 0 and 1 presenting with epiphora. They were examined to exclude other causes of lacrimation and epiphora: Slit-lamp assessment of the stenosed punctum and grading was done, probing was done to exclude associated canalicular stenosis, and syringing was done to exclude nasolacrimal duct obstruction...
December 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29216818/neuroprotective-effects-of-amiodarone-in-a-mouse-model-of-ischemic-stroke
#12
Masakazu Kotoda, Tadahiko Ishiyama, Kazuha Mitsui, Sohei Hishiyama, Takashi Matsukawa
BACKGROUND: Ion channels play a crucial role in the development of ischemic brain injury. Recent studies have reported that the blockade of various types of ion channels improves outcomes in experimental stroke models. Amiodarone, one of the most effective drugs for life-threatening arrhythmia, works as a multiple channel blocker and its characteristics cover all four Vaughan-Williams classes. Although it is known that amiodarone indirectly contributes to preventing ischemic stroke by maintaining sinus rhythm in patients with atrial fibrillation, the direct neuroprotective effect of amiodarone has not been clarified...
December 8, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/29216244/optimizing-household-survey-methods-to-monitor-the-sustainable-development-goals-targets-6-1-and-6-2-on-drinking-water-sanitation-and-hygiene-a-mixed-methods-field-test-in-belize
#13
Shane M Khan, Robert E S Bain, Karsten Lunze, Turgay Unalan, Bo Beshanski-Pedersen, Tom Slaymaker, Richard Johnston, Attila Hancioglu
BACKGROUND: The Sustainable Development Goals (SDGs) require household survey programmes such as the UNICEF-supported Multiple Indicator Cluster Surveys (MICS) to enhance data collection to cover new indicators. This study aims to evaluated methods for assessing water quality, water availability, emptying of sanitation facilities, menstrual hygiene management and the acceptability of water quality testing in households which are key to monitoring SDG targets 6.1 and 6.2 on drinking Water, Sanitation and Hygiene (WASH) and emerging issues...
2017: PloS One
https://www.readbyqxmd.com/read/29215681/oxygen-saturation-in-the-dental-pulp-of-maxillary-premolars-in-different-age-groups-part-1
#14
Carlos Estrela, Giuliano C Serpa, Ana Helena G Alencar, Kely F Bruno, Fernando B Barletta, Wilson T Felippe, Cyntia R A Estrela, João B Souza
The aim of this study was to determine oxygen saturation levels in the dental pulp of maxillary premolars in different age groups. A total of 120 human maxillary premolars with normal dental pulps were selected covering the following age groups: 20-24, 25-29, 30-34, 35-39 and 40-44 years (n=24 each group). Oxygen saturation was assessed using pulse oximetry. Analysis of variance was used to assess differences in oxygen saturation levels and Tukey's test was used to identify the age groups that differed from each other...
July 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29214870/advances-in-cell-free-protein-array-methods
#15
Xiaobo Yu, Brianne Petritis, Hu Duan, Danke Xu, Joshua LaBaer
Cell-free protein microarrays represent a special form of protein microarray which display proteins made fresh at the time of the experiment, avoiding storage and denaturation. They have been used increasingly in basic and translational research over the past decade to study protein-protein interactions, the pathogen-host relationship, post-translational modifications, and antibody biomarkers of different human diseases. Their role in the first blood-based diagnostic test for early stage breast cancer highlights their value in managing human health...
December 7, 2017: Expert Review of Proteomics
https://www.readbyqxmd.com/read/29214576/new-therapeutic-uses-for-existing-drugs
#16
Bobbie Ann Austin, Ami D Gadhia
Eighty percent of drugs that enter human clinical testing are never approved for use. This means that for every five drugs that make it into the clinic, there are four that failed to show effectiveness for treating the disease or condition the drug was designed to treat.This high failure rate means there are many existing, partially developed therapeutic candidates with known pharmacology, formulation, and potential toxicity. Finding new uses for existing experimental drugs or biologics "repositioning" builds upon previous research and development efforts, so new candidate therapies can be advanced to clinical trials for a new use more quickly than starting from scratch...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29211349/evaluation-of-the-cytotoxicity-of-selected-conventional-glass-ionomer-cements-on-human-gingival-fibroblasts
#17
Grażyna Marczuk-Kolada, Elżbieta Łuczaj-Cepowicz, Małgorzata Pawińska, Adam Hołownia
BACKGROUND: Dentistry materials are the most frequently used substitutes of human tissues. Therefore, an assessment of dental filling materials should cover not only their chemical, physical, and mechanical characteristics, but also their cytotoxicity. OBJECTIVES: To compare the cytotoxic effects of 13 conventional glass ionomer cements on human gingival fibroblasts. MATERIAL AND METHODS: The assessment was conducted using the MTT test. Six samples were prepared for each material...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29210601/ranking-quantitative-resistance-to-septoria-tritici-blotch-in-elite-wheat-cultivars-using-automated-image-analysis
#18
Petteri Karisto, Andreas Hund, Kang Yu, Jonas Anderegg, Achim Walter, Fabio Mascher, Bruce A McDonald, Alexey Mikaberidze
Quantitative resistance is likely to be more durable than major gene resistance for controlling Septoria tritici blotch (STB) on wheat. Earlier studies hypothesized that resistance affecting the degree of host damage, as measured by the percentage of leaf area covered by STB lesions, is distinct from resistance that affects pathogen reproduction, as measured by the density of pycnidia produced within lesions. We tested this hypothesis using a collection of 335 elite European winter wheat cultivars that was naturally infected by a diverse population of Zymoseptoria tritici in a replicated field experiment...
December 6, 2017: Phytopathology
https://www.readbyqxmd.com/read/29210331/phytocapping-an-alternate-cover-option-for-municipal-solid-waste-landfills
#19
Abhishek Khapre, Sunil Kumar, C Rajasekaran
Landfill gases are produced due to biodegradation of organic fraction of municipal solid waste (MSW) when water comes into contact with buried wastes under prevailing anaerobic condition. To minimize the percolation of water in landfills, the conventional approach like clay capping is still practiced in India. Gas extraction system, for collection gases from landfills, is proven to be an expensive technique. Thus, "Phytocapping" to mitigate landfill gases and to minimize percolation of water into the landfill can be one of the attractive alternatives...
December 6, 2017: Environmental Technology
https://www.readbyqxmd.com/read/29210300/fak-inhibitors-in-cancer-a-patent-review
#20
Peng-Cheng Lv, Ai-Qin Jiang, Wei-Ming Zhang, Hai-Liang Zhu
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that localizes at sites of cell adhesion to the extracellular matrix (ECM) and mediates signalling events downstream of integrin engagement of the ECM. FAK is known to regulate cell survival, proliferation and migration. Areas covered: FAK expression has also been shown to be up-regulated in many cancer types. Previous study also indicates that FAK-mediated signaling and functions are intrinsically involved in the progression of tumor aggressiveness, suggesting that FAK is a promising target for anticancer therapies...
December 6, 2017: Expert Opinion on Therapeutic Patents
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