Anne Linde Mak, Nienke Wassenaar, Anne-Marieke van Dijk, Marian Troelstra, Veera Houttu, Koen van Son, Stan Driessen, Diona Zwirs, Sandra van den Berg-Faay, Elizabeth Shumbayawonda, Jurgen Runge, Michail Doukas, Joanne Verheij, Ulrich Beuers, Max Nieuwdorp, Djuna L Cahen, Aart Nederveen, Oliver Gurney-Champion, Adriaan Holleboom
BACKGROUND & AIMS: Individuals with obesity may develop intrapancreatic fat deposition (IPFD) and fatty pancreas disease (FPD). Whether this causes inflammation and fibrosis and leads to pancreatic dysfunction is less established than for liver damage in metabolic dysfunction-associated steatotic liver disease (MASLD). Moreover, the interrelations of FPD and MASLD are poorly understood. Therefore, we aimed to assess IPFD and fibro-inflammation in relation to pancreatic function and liver disease severity in individuals with MASLD...
March 2024: JHEP reports: innovation in hepatology