keyword
https://read.qxmd.com/read/38492786/application-of-the-magnetic-resonance-3d-multiecho-dixon-sequence-for-quantifying-hepatic-iron-overload-and-steatosis-in-patients-with-thalassemia
#1
JOURNAL ARTICLE
Fanyu Zhao, Yidi Chen, Ting Zhou, Cheng Tang, Jiang Huang, Huiting Zhang, Stephan Kannengiesser, Liling Long
OBJECTIVE: To investigate the feasibility and diagnostic efficacy of a 3D multiecho Dixon (qDixon) research application for simultaneously quantifying the liver iron concentration (LIC) and steatosis in thalassemia patients. MATERIALS AND METHODS: This prospective study enrolled participants with thalassemia who underwent 3 T MRI of the liver for the evaluation of hepatic iron overload. The imaging protocol including qDixon and conventional T2* mapping based on 2D multiecho gradient echo (ME GRE) sequences respectively...
March 14, 2024: Magnetic Resonance Imaging
https://read.qxmd.com/read/38491129/synthetic-mri-and-amide-proton-transfer-weighted-mri-for-differentiating-between-benign-and-malignant-sinonasal-lesions
#2
JOURNAL ARTICLE
Ying Xiang, Qiujuan Zhang, Xin Chen, Honghong Sun, Xiaohui Li, Xiaocheng Wei, Jinman Zhong, Bo Gao, Wei Huang, Wenbin Liang, Haiqiao Sun, Quanxin Yang, Xiaoyong Ren
OBJECTIVES: To explore the value of the synthetic MRI (SyMRI), combined with amide proton transfer-weighted (APTw) MRI for quantitative and morphologic assessment of sinonasal lesions, which could provide relative scale for the quantitative assessment of tissue properties. METHODS: A total of 80 patients (31 malignant and 49 benign) with sinonasal lesions, who underwent the SyMRI and APTw examination, were retrospectively analyzed. Quantitative parameters (T1, T2, proton density (PD)) and APT % were obtained through outlining the region of interest (ROI) and comparing the two groups utilizing independent Student t test or a Wilcoxon test...
March 16, 2024: European Radiology
https://read.qxmd.com/read/38490931/early-and-accurate-diagnosis-of-steatotic-liver-by-artificial-intelligence-ai-supported-ultrasonography
#3
JOURNAL ARTICLE
Sergio Santoro, Mohamad Khalil, Hala Abdallah, Ilaria Farella, Antonino Noto, Giovanni Marco Dipalo, Piercarlo Villani, Leonilde Bonfrate, Agostino Di Ciaula, Piero Portincasa
OBJECTIVES: Steatotic liver disease is the most frequent chronic liver disease worldwide. Ultrasonography (US) is commonly employed for the assessment and diagnosis. Few information is available on the possible use of artificial intelligence (AI) to ameliorate the diagnostic accuracy of ultrasonography. MATERIALS AND METHODS: An AI-based algorithm was developed using a dataset of US images. We prospectively enrolled 134 patients for algorithm validation. Patients underwent abdominal US and Proton Density Fat Fraction MRI scans (MRI-PDFF), assumed as reference technique...
March 14, 2024: European Journal of Internal Medicine
https://read.qxmd.com/read/38490130/five-minute-knee-mri-an-ai-based-super-resolution-reconstruction-approach-for-compressed-sensing-a-validation-study-on-healthy-volunteers
#4
JOURNAL ARTICLE
Robert Terzis, Thomas Dratsch, Robert Hahnfeldt, Lajos Basten, Philip Rauen, Kristina Sonnabend, Kilian Weiss, Robert Reimer, David Maintz, Andra-Iza Iuga, Grischa Bratke
PURPOSE: To investigate the potential of combining Compressed Sensing (CS) and a newly developed AI-based super resolution reconstruction prototype consisting of a series of convolutional neural networks (CNN) for a complete five-minute 2D knee MRI protocol. METHODS: In this prospective study, 20 volunteers were examined using a 3T-MRI-scanner (Ingenia Elition X, Philips). Similar to clinical practice, the protocol consists of a fat-saturated 2D-proton-density-sequence in coronal, sagittal and transversal orientation as well as a sagittal T1-weighted sequence...
March 9, 2024: European Journal of Radiology
https://read.qxmd.com/read/38480098/novel-multiparametric-mri-detects-improved-future-liver-remnant-quality-post-dual-vein-embolization
#5
JOURNAL ARTICLE
Senthil Sundaravadanan, Fenella Ks Welsh, Pulkit Sethi, Shaheen Noorani, Ben A Cresswell, John J Connell, Sina K Knapp, Luis Núñez, J Michael Brady, Rajarshi Banerjee, Myrddin Rees
BACKGROUND: Optimisation of the future liver remnant (FLR) is crucial to outcomes of extended liver resections. This study aimed to assess the quality of the FLR before and after dual vein embolization (DVE) by quantitative multiparametric MRI. METHODS: Of 100 patients with liver metastases recruited in a clinical trial (Precision1:NCT04597710), ten consecutive patients with insufficient FLR underwent quantitative multiparametric MRI pre- and post-DVE (right portal and hepatic vein)...
February 13, 2024: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38476967/fast-field-echo-resembling-ct-using-restricted-echo-spacing-fracture-mr-sequence-can-provide-craniocervical-region-images-comparable-to-a-ct-in-dogs
#6
JOURNAL ARTICLE
Dongjae Lee, Eunjee Kim, Hyeonjae Woo, Chang-Yeop Jeon, Junghee Yoon, Jihye Choi
Magnetic resonance imaging (MRI) is essential for evaluating cerebellar compression in patients with craniocervical junction abnormalities (CJA). However, it is limited in depicting cortical bone because of its short T2 relaxation times, low proton density, and organized structure. Fast field echo resembling a computed tomography (CT) scan using restricted echo-spacing (FRACTURE) MRI, is a new technique that offers CT-like bone contrast without radiation. This study aimed to assess the feasibility of using FRACTURE MRI for craniocervical junction (CCJ) assessment compared with CT and conventional MRI, potentially reducing the need for multiple scans and radiation exposure, and simplifying procedures in veterinary medicine...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38465109/addition-of-dulaglutide-or-empagliflozin-to-standard-of-care-treatment-effect-on-liver-steatosis-in-patients-with-type-2-diabetes-mellitus
#7
JOURNAL ARTICLE
Emmanouil Koullias, Maria Papavdi, Stavros Athanasopoulos, Asimina Mitrakou, Melanie Deutsch, Pavlos Zoumpoulis, Emmanuel Manesis, Anastasia Thanopoulou, John Koskinas
Background Patients with liver steatosis and diabetes mellitus can benefit from medications like glucagon-like peptide 1 receptor agonists or sodium-glucose co-transporter 2 inhibitors, as far as both hyperglycemia and fatty liver are concerned. Studies comparing members of both these families have not yet been published. We aimed to compare the effects of Empagliflozin and Dulaglutide, focusing primarily on liver steatosis. Methodology This prospective, observational, controlled study enrolled 78 patients from two centers in Athens, Greece...
February 2024: Curēus
https://read.qxmd.com/read/38462830/quantitative-comparison-of-liver-volume-proton-density-fat-fraction-and-time-burden-between-automatic-whole-liver-segmentation-and-manual-sampling-mri-strategies-for-diagnosing-metabolic-dysfunction-associated-steatotic-liver-disease-in-obese-patients
#8
JOURNAL ARTICLE
Di Cao, Yifan Yang, Mengyi Li, Yang Liu, Dawei Yang, Hui Xu, Han Lv, Zhongtao Zhang, Peng Zhang, Xibin Jia, Zhenghan Yang
BACKGROUND: The performance of automatic liver segmentation and manual sampling MRI strategies needs be compared to determine interchangeability. OBJECTIVE: To compare automatic liver segmentation and manual sampling strategies (manual whole liver segmentation and standardized manual region of interest) for performance in quantifying liver volume and MRI-proton density fat fraction (MRI-PDFF), identifying steatosis grade, and time burden. METHODS: Fifty patients with obesity who underwent liver biopsy and MRI between December 2017 and November 2018 were included...
March 7, 2024: Current medical imaging
https://read.qxmd.com/read/38459346/altered-probe-pressure-and-body-position-increase-diagnostic-accuracy-for-men-and-women-in-detecting-hepatic-steatosis-using-quantitative-ultrasound
#9
JOURNAL ARTICLE
Marie Byenfeldt, Johan Kihlberg, Patrik Nasr, Christer Grönlund, Anna Lindam, Wolf C Bartholomä, Peter Lundberg, Mattias Ekstedt
OBJECTIVES: To evaluate the diagnostic performance of ultrasound guided attenuation parameter (UGAP) for evaluating liver fat content with different probe forces and body positions, in relation to sex, and compared with proton density fat fraction (PDFF). METHODS: We prospectively enrolled a metabolic dysfunction-associated steatotic liver disease (MASLD) cohort that underwent UGAP and PDFF in the autumn of 2022. Mean UGAP values were obtained in supine and 30° left decubitus body position with normal 4 N and increased 30 N probe force...
March 8, 2024: European Radiology
https://read.qxmd.com/read/38447349/nonalcoholic-fatty-liver-disease-bone-and-muscle-quality-in-prolactinoma-a-pilot-study
#10
JOURNAL ARTICLE
İmdat Eroğlu, Burcin Gonul Iremli, Aysegul Erkoc, Ilkay S Idilman, Deniz Yuce, Ebru Calik Kutukcu, Deniz Akata, Tomris Erbas
OBJECTIVE: Hyperprolactinemia has negative impacts on metabolism and musculoskeletal health. In this study, individuals with active prolactinoma were evaluated for nonalcoholic fatty liver disease (NAFLD) and musculoskeletal health, which are underemphasized in the literature. METHODS: Twelve active prolactinoma patients and twelve healthy controls matched by age, gender, and BMI were included. Magnetic resonance imaging-proton density fat fraction (MRI-PDFF) was used to evaluate hepatic steatosis and magnetic resonance elastography (MRE) to evaluate liver stiffness measurement (LSM)...
February 22, 2024: Journal of Clinical Densitometry
https://read.qxmd.com/read/38443786/a-rapid-multi-parametric-quantitative-mr-imaging-method-to-assess-parkinson-s-disease-a-feasibility-study
#11
JOURNAL ARTICLE
Min Duan, Rongrong Pan, Qing Gao, Xinying Wu, Hai Lin, Jianmin Yuan, Yamei Zhang, Lindong Liu, Youyong Tian, Tong Fu
BACKGROUND: MULTIPLEX is a single-scan three-dimensional multi-parametric MRI technique that provides 1 mm isotropic T1-, T2*-, proton density- and susceptibility-weighted images and the corresponding quantitative maps. This study aimed to investigate its feasibility of clinical application in Parkinson's disease (PD). METHODS: 27 PD patients and 23 healthy control (HC) were recruited and underwent a MULTIPLEX scanning. All image reconstruction and processing were automatically performed with in-house C + + programs on the Automatic Differentiation using Expression Template platform...
March 5, 2024: BMC Medical Imaging
https://read.qxmd.com/read/38441595/-imaging-of-the-anterior-cruciate-ligament-and-anterolateral-rotational-instability-of-the-knee-joint
#12
REVIEW
Benjamin Fritz
The anterior cruciate ligament (ACL) is essential for the stability of the knee joint and ACL tears are one of the most common sports injuries with a high incidence, especially in sports that require rotational movements and abrupt changes in direction. Injuries of the ACL are rarely isolated and are often accompanied by meniscal and other internal knee injuries, which increase the risk of osteoarthritis. The spectrum of ACL injuries includes strains, partial tears and complete tears. Magnetic resonance imaging (MRI) plays a pivotal role in the diagnostics as it can accurately depict not only the ACL but also accompanying injuries...
March 5, 2024: Radiologie (Heidelb)
https://read.qxmd.com/read/38428264/fast-spin-echo-mri-of-reservoir-core-plugs-with-a-variable-field-magnet
#13
JOURNAL ARTICLE
Rheya Rajeev, Andrés Ramírez Aguilera, Florea Marica, Laura Romero-Zerón, Bruce J Balcom
Fast Spin Echo MRI is now widely employed in biomedicine for proton density and T2 contrast imaging. Fast Spin Echo methods provide rapid data acquisition by employing multiple echoes to determine multiple k-space lines with single excitations. Due to the multi-exponential behavior of T2 in typical porous media, and the strong dependence of T2 on the details of the experiment, acquiring a proton density image with Fast Spin Echo methods requires favorable sample and acquisition parameters. In recent years, we have shown the value of pure phase encode Free Induction Decay based methods such as SPRITE...
February 14, 2024: Journal of Magnetic Resonance
https://read.qxmd.com/read/38418210/mash-resolution-index-development-and-validation-of-a-non-invasive-score-to-detect-histological-resolution-of-mash
#14
JOURNAL ARTICLE
Rohit Loomba, Maral Amangurbanova, Ricki Bettencourt, Egbert Madamba, Harris Siddiqi, Lisa Richards, Cynthia Behling, Claude B Sirlin, Mildred D Gottwald, Shibao Feng, Maya Margalit, Daniel Q Huang
BACKGROUND: Dynamic changes in non-invasive tests, such as changes in alanine aminotransferase (ALT) and MRI proton-density-fat-fraction (MRI-PDFF), may help to detect metabolic dysfunction-associated steatohepatitis (MASH) resolution, but a combination of non-invasive tests may be more accurate than either alone. We developed a novel non-invasive score, the MASH Resolution Index, to detect the histological resolution of MASH. METHODS: This study included a derivation cohort of 95 well-characterised adult participants (67% female) with biopsy-confirmed MASH who underwent contemporaneous laboratory testing, MRI-PDFF and liver biopsy at two time points...
February 28, 2024: Gut
https://read.qxmd.com/read/38415151/myelin-water-quantification-in-multiple-sclerosis-using-short-repetition-time-adiabatic-inversion-recovery-prepared-fast-spin-echo-stair-fse-imaging
#15
JOURNAL ARTICLE
Dina Moazamian, Hamidreza Shaterian Mohammadi, Jiyo S Athertya, Soo Hyun Shin, James Lo, Eric Y Chang, Jiang Du, Graeme M Bydder, Yajun Ma
BACKGROUND: Myelin water imaging (MWI) is a myelin-specific technique, which has great potential for the assessment of demyelination and remyelination. This study develops a new MWI method, which employs a short repetition time adiabatic inversion recovery (STAIR) technique in combination with a commonly used fast spin echo (FSE) sequence and provides quantification of myelin water (MW) fractions. METHOD: Whole-brain MWI was performed using the short repetition time adiabatic inversion recovery prepared-fast spin echo (STAIR-FSE) technique on eight healthy volunteers (mean age: 38±14 years, four-males) and seven patients with multiple sclerosis (MS) (mean age: 53...
February 1, 2024: Quantitative Imaging in Medicine and Surgery
https://read.qxmd.com/read/38409158/diagnostic-contribution-of-additional-sequences-to-the-evaluation-of-cord-lesions-in-patients-with-cervical-spinal-multiple-sclerosis-in-turkey-a-retrospective-study
#16
JOURNAL ARTICLE
B Yagdiran, B T Cakir, H Cetin
BACKGROUND: Multiple Sclerosis (MS) is the most common cause of non-traumatic disability in young adults. Spinal cord involvement is observed in 55-75% of patients with MS. AIM: To identify the strengths and shortcomings of sagittal phase-sensitive inversion recovery (PSIR), sagittal proton density/T2-weighted (PD/T2W), and axial turbo inversion recovery magnitude (TIRM) sequences in the detection of cervical MS plaques by comparing with routine sequences (axial and sagittal T2W, sagittal T1W, sagittal TIRM, fat-suppressed contrast T1W) and therefore determine their diagnostic contributions...
February 1, 2024: Nigerian Journal of Clinical Practice
https://read.qxmd.com/read/38407264/validation-of-a-screening-panel-for-pediatric-metabolic-dysfunction-associated-steatotic-liver-disease-using-metabolomics
#17
JOURNAL ARTICLE
Helaina E Huneault, Alasdair E Gent, Catherine C Cohen, Zhulin He, Zachery R Jarrell, Rishikesan Kamaleswaran, Miriam B Vos
BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as NAFLD, is the most common liver disease in children. Liver biopsy remains the gold standard for diagnosis, although more efficient screening methods are needed. We previously developed a novel NAFLD screening panel in youth using machine learning applied to high-resolution metabolomics and clinical phenotype data. Our objective was to validate this panel in a separate cohort, which consisted of a combined cross-sectional sample of 161 children with stored frozen samples (75% male, 12...
March 1, 2024: Hepatology Communications
https://read.qxmd.com/read/38393403/utilizing-fully-automated-3d-organ-segmentation-for-hepatic-steatosis-assessment-with-ct-attenuation-based-parameters
#18
JOURNAL ARTICLE
Jeongin Yoo, Ijin Joo, Sun Kyung Jeon, Junghoan Park, Soon Ho Yoon
OBJECTIVES: To investigate the clinical utility of fully-automated 3D organ segmentation in assessing hepatic steatosis on pre-contrast and post-contrast CT images using magnetic resonance spectroscopy (MRS)-proton density fat fraction (PDFF) as reference standard. MATERIALS AND METHODS: This retrospective study analyzed 362 adult potential living liver donors with abdominal CT scans and MRS-PDFF. Using a deep learning-based tool, mean volumetric CT attenuation of the liver and spleen were measured on pre-contrast (liver(L)_pre and spleen(S)_pre) and post-contrast (L_post and S_post) images...
February 23, 2024: European Radiology
https://read.qxmd.com/read/38389373/7-tesla-mri-liver-fat-quantification-in-mice-data-quality-assessment
#19
JOURNAL ARTICLE
Stefan Polei, Tobias Lindner, Kerstin Abshagen, Marie Liebig, Bernd J Krause, Brigitte Vollmar, Marc-André Weber
PURPOSE: The objective of this study was to evaluate the robustness of proton density fat fraction (PDFF) data determined by magnetic resonance imaging (MRI) and spectroscopy (MRS) via spatially resolved error estimation. MATERIALS AND METHODS: Using standard T2* relaxation time measurement protocols, in-vivo and ex-vivo MRI data with water and fat nominally in phase or out of phase relative to each other were acquired on a 7 T small animal scanner. Based on a total of 24 different echo times, PDFF maps were calculated in a magnitude-based approach...
2024: Current medical imaging
https://read.qxmd.com/read/38385182/assessing-the-pulmonary-vascular-responsiveness-to-oxygen-with-proton-mri
#20
JOURNAL ARTICLE
Abhilash S Kizhakke Puliyakote, Vincent Tedjasaputra, Gregory M Petersen, Rui Carlos Sá, Susan R Hopkins
Ventilation-perfusion matching occurs passively and is also actively regulated through hypoxic pulmonary vasoconstriction (HPV). The extent of HPV activity in humans, particularly normal subjects is uncertain. Current evaluation of HPV assesses changes in ventilation-perfusion relationships/pulmonary vascular resistance with hypoxia and are invasive, or unsuitable for patients because of safety concerns. We used a non-invasive imaging-based approach to quantify the pulmonary vascular response to oxygen as a metric of HPV by measuring perfusion changes between breathing 21% and 30%O2 using arterial spin labeling (ASL) MRI...
February 22, 2024: Journal of Applied Physiology
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