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https://www.readbyqxmd.com/read/27869344/the-importance-of-materials-design-to-make-ions-flow-toward-novel-materials-platforms-for-bioelectronics-applications
#1
Celia M Pacheco-Moreno, Murielle Schreck, Alberto D Scaccabarozzi, Philippe Bourgun, Guillaume Wantz, Molly M Stevens, Olivier J Dautel, Natalie Stingelin
Chemical design criteria for materials for bioelectronics applications using a series of copolymer derivatives based on poly(3-hexylthiophene) are established. Directed chemical design via side-chain functionalization with polar groups allows manipulation of ion transport and ion-to-electron transduction. Insights gained will permit increased use of the plethora of materials employed in the organic electronics area for application in the bioelectronics field.
November 21, 2016: Advanced Materials
https://www.readbyqxmd.com/read/27853136/formation-of-bacterial-pilus-like-nanofibres-by-designed-minimalistic-self-assembling-peptides
#2
Tom Guterman, Micha Kornreich, Avigail Stern, Lihi Adler-Abramovich, Danny Porath, Roy Beck, Linda J W Shimon, Ehud Gazit
Mimicking the multifunctional bacterial type IV pili (T4Ps) nanofibres provides an important avenue towards the development of new functional nanostructured biomaterials. Yet, the development of T4Ps-based applications is limited by the inability to form these nanofibres in vitro from their pilin monomers. Here, to overcome this limitation, we followed a reductionist approach and designed a self-assembling pilin-based 20-mer peptide, derived from the presumably bioelectronic pilin of Geobacter sulfurreducens...
November 17, 2016: Nature Communications
https://www.readbyqxmd.com/read/27846985/array-of-biosensors-for-discrimination-of-grapes-according-to-grape-variety-vintage-and-ripeness
#3
C Medina-Plaza, J A de Saja, J A Fernández-Escudero, E Barajas, G Medrano, M L Rodriguez-Mendez
A bioelectronic tongue based on nanostructured biosensors specific for the simultaneous detection of sugars and phenols has been developed. The array combined oxidases and dehydrogenases immobilized on a lipidic layer prepared using the Langmuir-Blodgett technique where Glucose oxidase, d-Fructose dehydrogenase, Tyrosinase or Laccase were imbibed. A phthalocyanine was co-immobilized in the sensing layer and used as electron mediator. The array thus formed has been used to analyze grapes and provides global information about the samples while providing specific information about their phenolic and their sugar content...
December 1, 2016: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27836602/a-biomimetic-bioelectronic-tongue-a-switch-for-on-and-off-response-of-acid-sensations
#4
Wei Zhang, Peihua Chen, Lianqun Zhou, Zhen Qin, Keqiang Gao, Jia Yao, Chuanyu Li, Ping Wang
The perception of sour taste in mammals is important for its basic modality properties and avoiding toxic substances. We explore a biomimetic bioelectronic tongue, which integrate MEA (microelectrode array) and taste receptor cell for acid detection as a switch. However, the acid-sensing mechanism and coding of the taste receptor cells in the periphery is not well understood, with long-standing debate. Therefore, we firstly construct a Hodgkin-Huxley type mathematical model of whole-cell acid-sensing taste receptor cells based on the electrophysiologic patch clamp recordings with different acid sensitive receptor expressing and different acidic stimulations...
October 27, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27836601/generation-of-electrical-power-under-human-skin-by-subdermal-solar-cell-arrays-for-implantable-bioelectronic-devices
#5
Kwangsun Song, Jung Hyun Han, Hyung Chae Yang, Kwang Il Nam, Jongho Lee
Medical electronic implants can significantly improve people's health and quality of life. These implants are typically powered by batteries, which usually have a finite lifetime and therefore must be replaced periodically using surgical procedures. Recently, subdermal solar cells that can generate electricity by absorbing light transmitted through skin have been proposed as a sustainable electricity source to power medical electronic implants in bodies. However, the results to date have been obtained with animal models...
November 3, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27823988/advances-in-nanowire-bioelectronics
#6
Wei Zhou, Xiaochuan Dai, Charles M Lieber
Semiconductor nanowires represent powerful building blocks for next generation bioelectronics given their attractive properties, including nanometer-scale footprint comparable to subcellular structures and bio-molecules, configurable in nonstandard device geometries readily interfaced with biological systems, high surface-to-volume ratios, fast signal responses, and minimum consumption of energy. In this review article, we summarize recent progress in the field of nanowire bioelectronics with a focus primarily on silicon nanowire field-effect transistor biosensors...
November 8, 2016: Reports on Progress in Physics
https://www.readbyqxmd.com/read/27818050/protein-capped-cu-nanoclusters-swcnt-nanocomposite-as-a-novel-candidate-of-high-performance-platform-for-organophosphates-enzymeless-biosensor
#7
Hasan Bagheri, Abbas Afkhami, Hosein Khoshsafar, Ali Hajian, Alireza Shahriyari
A biocompatible nanocomposite including bovine serum albumin (BSA) template Cu nanoclusters (CuNCs@BSA) and single-walled carbon nanotubes (SWCNT) was synthesized to fabricate a highly sensitive electrochemical biosensor for paraoxon as a model of organophosphates. The UV-vis, fluorescence and Fourier transform infrared (FTIR) demonstrated that BSA entrapped in the nanocomposite film have been changed in its secondary structure so that it provided an enzyme like activity attributing to the high electrical conductivity of the entrapped copper nanoclusters...
October 4, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27816589/enhanced-electrocatalytic-performance-of-an-ultrafine-aupt-nanoalloy-framework-embedded-in-graphene-towards-epinephrine-sensing
#8
Tran Duy Thanh, Jayaraman Balamurugan, Nguyen Thanh Tuan, Hun Jeong, Seung Hee Lee, Nam Hoon Kim, Joong Hee Lee
A novel hierarchical nanoporous thin film of AuPt alloy embedded in graphene (AuPt@GR) was successfully synthesized through the self-assembly of ultrafine AuPt nanoparticles (~3nm) within GR sheets by means of a facile chemical vapor deposition (CVD) procedure without the use of any external organic capping agent and reducing agent. A binder-free sensor based on the AuPt@GR hybrid material was fabricated and its electrocatalytic activity was evaluated by using it to determine epinephrine (EP) in PBS solution (pH=7...
September 23, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27801905/happy-together-microbial-communities-that-hook-up-to-swap-electrons
#9
Derek R Lovley
The discovery of direct interspecies electron transfer (DIET) and cable bacteria has demonstrated that microbial cells can exchange electrons over long distances (μm-cm) through electrical connections. For example, in the presence of cable bacteria electrons are rapidly transported over centimeter distances, coupling the oxidation of reduced sulfur compounds in anoxic sediments to oxygen reduction in overlying surficial sediments. Bacteria and archaea wired for DIET are found in anaerobic methane-producing and methane-consuming communities...
November 1, 2016: ISME Journal
https://www.readbyqxmd.com/read/27791191/correction-for-jonsson-et-al-bioelectronic-neural-pixel-chemical-stimulation-and-electrical-sensing-at-the-same-site
#10
(no author information available yet)
No abstract text is available yet for this article.
October 17, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27779812/a-mussel-inspired-conductive-self-adhesive-and-self-healable-tough-hydrogel-as-cell-stimulators-and-implantable-bioelectronics
#11
Lu Han, Xiong Lu, Menghao Wang, Donglin Gan, Weili Deng, Kefeng Wang, Liming Fang, Kezhi Liu, Chun Wai Chan, Youhong Tang, Lu-Tao Weng, Huipin Yuan
A graphene oxide conductive hydrogel is reported that simultaneously possesses high toughness, self-healability, and self-adhesiveness. Inspired by the adhesion behaviors of mussels, our conductive hydrogel shows self-adhesiveness on various surfaces and soft tissues. The hydrogel can be used as self-adhesive bioelectronics, such as electrical stimulators to regulate cell activity and implantable electrodes for recording in vivo signals.
October 25, 2016: Small
https://www.readbyqxmd.com/read/27771137/recent-advances-in-2d-bioelectronics
#12
Adeniyi Olugbenga Osikoya, Ashutosh Tiwari
No abstract text is available yet for this article.
October 11, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27713414/n-type-organic-electrochemical-transistors-with-stability-in-water
#13
Alexander Giovannitti, Christian B Nielsen, Dan-Tiberiu Sbircea, Sahika Inal, Mary Donahue, Muhammad R Niazi, David A Hanifi, Aram Amassian, George G Malliaras, Jonathan Rivnay, Iain McCulloch
Organic electrochemical transistors (OECTs) are receiving significant attention due to their ability to efficiently transduce biological signals. A major limitation of this technology is that only p-type materials have been reported, which precludes the development of complementary circuits, and limits sensor technologies. Here, we report the first ever n-type OECT, with relatively balanced ambipolar charge transport characteristics based on a polymer that supports both hole and electron transport along its backbone when doped through an aqueous electrolyte and in the presence of oxygen...
October 7, 2016: Nature Communications
https://www.readbyqxmd.com/read/27713411/electronic-control-of-h-current-in-a-bioprotonic-device-with-gramicidin-a-and-alamethicin
#14
Zahra Hemmatian, Scott Keene, Erik Josberger, Takeo Miyake, Carina Arboleda, Jessica Soto-Rodríguez, François Baneyx, Marco Rolandi
In biological systems, intercellular communication is mediated by membrane proteins and ion channels that regulate traffic of ions and small molecules across cell membranes. A bioelectronic device with ion channels that control ionic flow across a supported lipid bilayer (SLB) should therefore be ideal for interfacing with biological systems. Here, we demonstrate a biotic-abiotic bioprotonic device with Pd contacts that regulates proton (H(+)) flow across an SLB incorporating the ion channels Gramicidin A (gA) and Alamethicin (ALM)...
October 7, 2016: Nature Communications
https://www.readbyqxmd.com/read/27692376/nickel-electrodes-as-a-cheap-and-versatile-platform-for-studying-structure-and-function-of-immobilized-redox-proteins
#15
Xiao Xia Han, Junbo Li, Ibrahim Halil Öner, Bing Zhao, Silke Leimkühler, Peter Hildebrandt, Inez M Weidinger
Practical use of many bioelectronic and bioanalytical devices is limited by the need of expensive materials and time consuming fabrication. Here we demonstrate the use of nickel electrodes as a simple and cheap solid support material for bioelectronic applications. The naturally nanostructured electrodes showed a surprisingly high electromagnetic surface enhancement upon light illumination such that immobilization and electron transfer reactions of the model redox proteins cytochrome b5 (Cyt b5) and cytochrome c (Cyt c) could be followed via surface enhanced resonance Raman spectroscopy...
October 19, 2016: Analytica Chimica Acta
https://www.readbyqxmd.com/read/27687473/on-the-mechanism-of-ubiquinone-mediated-photocurrent-generation-by-a-reaction-center-based-photocathode
#16
Vincent M Friebe, David J K Swainsbury, Paul K Fyfe, Wessel van der Heijden, Michael R Jones, Raoul N Frese
Upon photoexcitation, the reaction center (RC) pigment-proteins that facilitate natural photosynthesis achieve a metastable separation of electrical charge among the embedded cofactors. Because of the high quantum efficiency of this process, there is a growing interest in their incorporation into biohybrid materials for solar energy conversion, bioelectronics and biosensing. Multiple bioelectrochemical studies have shown that reaction centers from various photosynthetic organisms can be interfaced with diverse electrode materials for the generation of photocurrents, but many mechanistic aspects of native protein functionality in a non-native environment is unknown...
December 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27686216/development-of-dopant-free-conductive-bioelastomers
#17
Cancan Xu, Yihui Huang, Gerardo Yepez, Zi Wei, Fuqiang Liu, Alejandro Bugarin, Liping Tang, Yi Hong
Conductive biodegradable materials are of great interest for various biomedical applications, such as tissue repair and bioelectronics. They generally consist of multiple components, including biodegradable polymer/non-degradable conductive polymer/dopant, biodegradable conductive polymer/dopant or biodegradable polymer/non-degradable inorganic additives. The dopants or additives induce material instability that can be complex and possibly toxic. Material softness and elasticity are also highly expected for soft tissue repair and soft electronics...
September 30, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27664409/a-portable-and-multiplexed-bioelectronic-sensor-using-human-olfactory-and-taste-receptors
#18
Manki Son, Daesan Kim, Hwi Jin Ko, Seunghun Hong, Tai Hyun Park
A multiplexed bioelectronic sensor was developed for the purpose of rapid, on-site, and simultaneous detection of various target molecules. Olfactory and taste receptors were produced in Escherichia coli, and the reconstituted receptors were immobilized onto a multi-channel type carbon nanotube field-effect transistor. This device mimicked the human olfactory/taste system and simultaneously measured the conductance changes with high sensitivity and selectivity following treatment with various odor and taste molecules commonly known to be indicators of food contamination...
September 17, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27660017/corrigendum-to-a-microfluidic-device-for-the-automated-electrical-readout-of-low-density-glass-slide-microarrays-biosens-bioelectron-74-2015-698-704
#19
María Díaz-González, J Pablo Salvador, Diana Bonilla, M Pilar Marco, César Fernández-Sánchez, Antonio Baldi
No abstract text is available yet for this article.
September 19, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27639492/supermolecules-of-poly-n-isopropylacrylamide-complexating-herring-sperm-dna-with-bio-multiple-hydrogen-bonding
#20
Ai-Wei Lee, Cheng-Chen Hsu, Yi-Zu Liu, Po-Li Wei, Jem-Kun Chen
In this study we used the poly(N-isopropylacrylamide) (PNIPAAm) as a medium to blend with an organic DNA, herring sperm DNA (HSD), to generate PNIPAAm-HSD supramolecular complexes. Bio-multiple hydrogen bonding (BMHB) between PNIPAAm and HSD was investigated that changed the temperature responsiveness of PNIPAAm relatively to the HSD concentrations. With blending the HSD into PNIPAAm matrix, the phase separation in solution is completely opposite from that of neat PNIPAAm. Surface property in static water contact angle (SWCA) is also opposite from that of pure PNIPAAm upon increasing HSD content over 60%...
September 12, 2016: Colloids and Surfaces. B, Biointerfaces
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