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https://www.readbyqxmd.com/read/28088750/continuous-minimally-invasive-alcohol-monitoring-using-microneedle-sensor-arrays
#1
A M Vinu Mohan, Joshua Ray Windmiller, Rupesh K Mishra, Joseph Wang
The present work describes an attractive skin-worn microneedle sensing device for the minimally invasive electrochemical monitoring of subcutaneous alcohol. The device consists of an assembly of pyramidal microneedle structures integrated with Pt and Ag wires, each with a microcavity opening. The microneedle aperture was modified by electropolymerizing o-phenylene diamine onto the Pt wire microtransducer, followed by the immobilization of alcohol oxidase (AOx) in an intermediate chitosan layer, along with an outer Nafion layer...
January 10, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28087359/the-effect-of-nmda-r-antagonism-on-simultaneously-acquired-local-field-potentials-and-tissue-oxygen-levels-in-the-brains-of-freely-moving-rats
#2
John Kealy, Sean Commins, John P Lowry
Non-competitive NMDA receptor antagonists are known to induce psychosis-like symptoms in rodents. Administration of such compounds cause behavioural effects such as memory impairment and hyperlocomotion. Additionally, drugs such as phencyclidine (PCP), ketamine and MK-801 all cause distinctive increases in striatal local field potential (LFP) in the high frequency oscillation (HFO) band in the power spectrum (140-180 Hz). Amperometric sensors provide a means to measure tissue oxygen (tO2; a BOLD-like signal) in the brains of freely-moving rats while simultaneously acquiring LFP using the same electrode...
January 10, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28086891/measurement-of-electrocardiograms-in-a-bath-through-tap-water-utilizing-capacitive-coupling-electrodes-placed-outside-the-bathtub-wall
#3
Kosuke Motoi, Yasuhiro Yamakoshi, Takehiro Yamakoshi, Hiroaki Sakai, Naoto Tanaka, Ken-Ichi Yamakoshi
BACKGROUND: Taking a bath sometimes poses a risk for subjects with chronic cardiopulmonary disorders, due to the thermal effect and water pressure on his/her body. The ECG measurement would be helpful for the early recognition of abnormal cardiac beats and respiratory conditions. This paper describes a new attempt to improve on previous bathtub ECG measurement techniques that had electrodes placed inside the bathtub that were intrusive to the subjects' bathing experience. This study is concerned with the initial development of a method to measure an electrocardiogram (ECG) through tap water without conscious awareness of the presence of electrodes that are placed outside the bathtub wall...
January 11, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/28075594/high-curvature-nanostructuring-enhances-probe-display-for-biomolecular-detection
#4
Phil De Luna, Sahar Mahshid, Jagotamoy Das, Binquan Luan, Edward H Sargent, Shana O Kelley, Ruhong Zhou
High-curvature electrodes facilitate rapid and sensitive detection of a broad class of molecular analytes. These sensors have reached detection limits not attained using bulk macroscale materials. It has been proposed that immobilized DNA probes are displayed at a high deflection angle on the sensor surface, allowing greater accessibility and more efficient hybridization. Here we report the first use of all-atom molecular dynamics simulations coupled with electrochemical experiments to explore the dynamics of ssDNA immobilized on high-curvature vs...
January 11, 2017: Nano Letters
https://www.readbyqxmd.com/read/28075341/a-non-invasive-multichannel-hybrid-fiber-optic-sensor-system-for-vital-sign-monitoring
#5
Marcel Fajkus, Jan Nedoma, Radek Martinek, Vladimir Vasinek, Homer Nazeran, Petr Siska
In this article, we briefly describe the design, construction, and functional verification of a hybrid multichannel fiber-optic sensor system for basic vital sign monitoring. This sensor uses a novel non-invasive measurement probe based on the fiber Bragg grating (FBG). The probe is composed of two FBGs encapsulated inside a polydimethylsiloxane polymer (PDMS). The PDMS is non-reactive to human skin and resistant to electromagnetic waves, UV absorption, and radiation. We emphasize the construction of the probe to be specifically used for basic vital sign monitoring such as body temperature, respiratory rate and heart rate...
January 8, 2017: Sensors
https://www.readbyqxmd.com/read/28074385/use-of-a-cd-laser-pickup-head-to-fabricate-microelectrodes-in-polymethylmethacrylate-substrates-for-biosensing-applications
#6
Jehú López-Aparicio, Mathieu Hautefeuille, Sara Herrera-Domínguez, Adriana Razo-de-León, Mariel Cano-Jorge, Ixchetl Rojas-Benito, Mariana Centeno-Sierra, Tatiana Fiordelisio-Coll, Catalina Elizabeth Stern-Forgach
In this work, we report a simple fabrication method for microelectrodes on a polymethylmethacrylate substrate, using a low-cost laser platform based on a CD-DVD unit for direct rapid-prototyping. We used this laser microfabrication technique to etch any desired design on polymethylmethacrylate substrates to produce microchannels with controlled geometry, with a highly repeatable micron-scale resolution. Those shallow microchannels were then filled with a conductive paste of material of our choice that was converted into microelectrodes of desired shapes and geometries after drying...
March 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28071593/a-lightweight-feedback-controlled-microdrive-for-chronic-neural-recordings
#7
Aleksander Jovalekic, Sophie Cave Lopez, Alessandro Canopoli, Janie Ondracek, Aymeric Nager, Alexei Vyssotski, Richard Hans Robert Hahnloser
OBJECTIVE: Chronic neural recordings have provided many insights into the relationship between neural activity and behavior. We set out to develop a miniaturized motorized microdrive that allows precise electrode positioning despite possibly unreliable motors. APPROACH: We designed a feedback-based motor control mechanism. It contains an integrated position readout from an array of magnets and a Hall sensor. MAIN RESULTS: Our extremely lightweight (<1 g) motorized microdrive allows remote positioning of both metal electrodes and glass pipettes along one motorized axis...
January 10, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28068083/simultaneous-electrochemical-detection-of-benzimidazole-fungicides-carbendazim-and-thiabendazole-using-a-novel-nano-hybrid-material-modi%C3%AF-ed-electrode
#8
Yuanyuan Dong, Lijun Yang, Lei Zhang
In this work, a novel ZnFe2O4/SWCNTs nano-hybrid was successfully synthesized as electrode materials and applied to the simultaneous quantitative determination of carbendazim (CBZ) and thiabendazole (TBZ). The electrochemical behaviors of CBZ and TBZ on the ZnFe2O4/SWCNTs/GCE were investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The electrochemical active area of modified electrode was calculated, which is nearly 5.5 times that of the bare electrode. The influence of various factors such as accumulation time, pH and scan rates, type of surfactant, and the electrochemical reaction mechanism were studied...
January 9, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28067788/mixed-potential-gas-sensors-using-an-electrolyte-consisting-of-zinc-phosphate-glass-and-benzimidazole
#9
Takafumi Akamatsu, Toshio Itoh, Woosuck Shin
Mixed-potential gas sensors with a proton conductor consisting of zinc metaphosphate glass and benzimidazole were fabricated for the detection of hydrogen produced by intestinal bacteria in dry and humid air. The gas sensor consisting of an alumina substrate with platinum and gold electrodes showed good response to different hydrogen concentrations from 250 parts per million (ppm) to 25,000 ppm in dry and humid air at 100-130 °C. The sensor response varied linearly with the hydrogen and carbon monoxide concentrations due to mass transport limitations...
January 5, 2017: Sensors
https://www.readbyqxmd.com/read/28061420/a-bioinspired-ionic-liquid-tagged-cobalt-salophen-complex-for-nonenzymatic-detection-of-glucose
#10
Michael Benjamin, Devaraj Manoj, Kathavarayan Thenmozhi, Pundlik Rambhau Bhagat, Duraisamy Saravanakumar, Sellappan Senthilkumar
The development of efficient and cost effective nonenzymatic biosensors with remarkable sensitivity, selectivity and stability for the detection of biomolecules, especially glucose is one of the major challenges in materials- and electrochemistry. Herein, we report the design and preparation of nonenzymatic biosensor based on an ionic liquid tagged cobalt-salophen metal complex (Co-salophen-IL) immobilized on electrochemically reduced graphene oxide (ERGO) for the detection of glucose via an electrochemical oxidation...
December 30, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28060706/comparison-of-the-thermal-degradation-of-heavily-nb-doped-and-normal-pzt-thin-films
#11
Jeong-Suong Yang, Yunsung Kang, Inyoung Kang, Seungmo Lim, Seung-Joo Shin, Jungwon Lee, Kangheon Hur
The degradation of Niobium-doped lead zirconate titanate (PZT) and two types of PZT thin films were investigated. Undoped PZT, 2-step PZT and heavily Nb-doped PZT (PNZT) around the morphotropic phase boundary (MPB) were in-situ deposited under optimum condition by RF-magnetron sputtering. All 2 μm thick films had dense perovskite columnar grain structure and self-polarized (100) dominant orientation. PZT thin films were deposited on Pt/TiOx bottom electrode on Si wafer, and Nb doped PZT thin film was on Ir/TiW electrode with help of orientation control...
January 4, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28059063/local-probing-of-magnetoelectric-properties-of-pvdf-fe3o4-electrospun-nanofibers-by-piezoresponse-force-microscopy
#12
Tian Zheng, Zhilian Yue, Gordon G Wallace, Yi Du, Pedro Martins, Senentxu Lanceros-Mendez, Michael J Higgins
The coupling of magnetic and electric properties in polymer-based magnetoelectric composites offers new opportunities to develop contactless electrodes, effectively without electrical connections, for less-invasive integration into devices such as energy harvesters, sensors, wearable and implantable electrodes. Understanding the macroscale-to-nanoscale conversion of the properties is important, as nanostructured and nanoscale magnetoelectric structures are increasingly fabricated. However, whilst the magnetoelectric effect at the macroscale is well established both theoretically and experimentally, it remains unclear how this effect translates to the nanoscale, or vice versa...
January 6, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28058420/sensitized-zno-nanorod-assemblies-to-detect-heavy-metal-contaminated-phytomedicines-spectroscopic-and-simulation-studies
#13
Damayanti Bagchi, Tuhin Kumar Maji, Samim Sardar, Peter Lemmens, Chinmoy Bhattacharya, Debjani Karmakar, Samir Kumar Pal
The immense pharmacological relevance of the herbal medicine curcumin including anti-cancer and anti-Alzheimer effects, suggests it to be a superior alternative to synthesised drugs. The diverse functionalities with minimal side effects intensify the use of curcumin not only as a dietary supplement but also as a therapeutic agent. Besides all this effectiveness, some recent literature reported the presence of deleterious heavy metal contaminants from various sources in curcumin leading to potential health hazards...
January 6, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28056170/self-sterilized-flexible-single-electrode-triboelectric-nanogenerator-for-energy-harvesting-and-dynamic-force-sensing
#14
Huijuan Guo, Tao Li, Xiaotao Cao, Jin Xiong, Yang Jie, Magnus Willander, Xia Cao, Ning Wang, Zhong Lin Wang
Triboelectric nanogenerators (TENGs) offer great opportunities to deploy advanced wearable electronics that integrate a power generator and smart sensor, which eliminates the associated cost and sustainability concerns. Here, an embodiment of such integrated platforms has been presented in a graphene oxide (GO) based single-electrode TENG (S-TENG). The as-designed multifunctional device could not only harvest tiny bits of mechanical energy from ambient movements with a high power density of 3.13 W·m(-2) but also enable detecting dynamic force with an excellent sensitivity of about 388 μA·MPa(-1)...
January 9, 2017: ACS Nano
https://www.readbyqxmd.com/read/28054398/chemically-robust-ambipolar-organic-transistor-array-directly-patterned-by-photolithography
#15
Eun Kwang Lee, Cheol Hee Park, Junghoon Lee, Hae Rang Lee, Changduk Yang, Joon Hak Oh
Organic ambipolar transistor arrays for chemical sensors are prepared on a flexible plastic substrate with a bottom-gate bottom-contact configuration to minimize the damage to the organic semiconductors, for the first time, using a photolithographically patternable polymer semiconductor. Well-balanced ambipolar charge transport has been achieved by introducing graphene electrodes because of the reduced contact resistance and energetic barrier for electron transport.
January 5, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28050904/paper-based-analytical-biosensor-chip-designed-from-graphene-nanoplatelet-amphiphilic-di-block-co-polymer-composite-for-cortisol-detection-in-human-saliva
#16
Muhammad Khan, Santosh K Misra, Zhen Wang, Enrique A Daza, Aaron Schwartz-Duval, Joseph Kus, Debanjan Pan, Dipanjan Pan
Cortisol has been identified as a biomarker in saliva to monitor psychological stress. In this work, we report label-free paper-based electrical biosensor chip to quantify salivary cortisol at a point-of-care (POC) level. A high specificity of the sensor chip to detect cortisol with detection limit of 3 pg/mL was achieved by conjugating anti-cortisol antibody (anti-CAB) on top of gold (Au) microelectrodes using 3,3'-Dithiodipropionic acid di(N-hydroxysuccinimide ester (DTSP) - as self-assembled monolayer (SAM) agent...
January 4, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28049107/electrochemical-sensor-based-on-magnetic-molecularly-imprinted-nanoparticles-modified-magnetic-electrode-for-determination-of-hb
#17
Binghua Sun, Xinjiong Ni, Yuhua Cao, Guangqun Cao
A fast and selective electrochemical sensor for determination of hemoglobin (Hb) was developed based on magnetic molecularly imprinted nanoparticles modified on the magnetic glassy carbon electrode. The nanoparticles Fe3O4@SiO2 with a magnetic core and a molecularly imprinted shell had regular structures and good monodispersity. Hb could be determined directly by electrochemical oxidization with the modified electrode. A magnetic field increased electrochemical response to Hb by two times. Imprinting Hb on the surface of Fe3O4@SiO2 shortened the response time within 7min...
December 28, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28046344/mo-ab-bra-07-low-dose-imaging-with-avalanche-amorphous-selenium-flat-panel-imager
#18
J Scheuermann, A Howansky, A Goldan, S Leveille, O Tousignant, K Tanioka, W Zhao
PURPOSE: We present the first active matrix flat panel imager (AMFPI) capable of producing x-ray quantum noise limited images at low doses by overcoming the electronic noise through signal amplification by photoconductive avalanche gain (gav). The indirect detector fabricated uses an optical sensing layer of amorphous selenium (a-Se) known as High-Gain Avalanche Rushing Photoconductor (HARP). The detector design is called Scintillator HARP (SHARP)-AMFPI. This is the first image sensor to utilize solid-state HARP technology...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28042868/a-3d-faraday-shield-for-interdigitated-dielectrometry-sensors-and-its-effect-on-capacitance
#19
Alex Risos, Nicholas Long, Arvid Hunze, Gideon Gouws
Interdigitated dielectrometry sensors (IDS) are capacitive sensors investigated to precisely measure the relative permittivity ( ϵ r ) of insulating liquids. Such liquids used in the power industry exhibit a change in ϵ r as they degrade. The IDS ability to measure ϵ r in-situ can potentially reduce maintenance, increase grid stability and improve safety. Noise from external electric field sources is a prominent issue with IDS. This paper investigates the novelty of applying a Faraday cage onto an IDS as a 3D shield to reduce this noise...
December 31, 2016: Sensors
https://www.readbyqxmd.com/read/28042843/evaluation-of-surface-cleaning-procedures-in-terms-of-gas-sensing-properties-of-spray-deposited-cnt-film-thermal-and-o%C3%A2-plasma-treatments
#20
Joon Hyub Kim, Min-Jung Song, Ki Beom Kim, Joon-Hyung Jin, Nam Ki Min
The effect of cleaning the surface of single-walled carbon nanotube (SWNT) networks by thermal and the O₂ plasma treatments is presented in terms of NH₃ gas sensing characteristics. The goal of this work is to determine the relationship between the physicochemical properties of the cleaned surface (including the chemical composition, crystal structure, hydrophilicity, and impurity content) and the sensitivity of the SWNT network films to NH₃ gas. The SWNT networks are spray-deposited on pre-patterned Pt electrodes, and are further functionalized by heating on a programmable hot plate or by O₂ plasma treatment in a laboratory-prepared plasma chamber...
December 30, 2016: Sensors
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