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Bainbridge; cardiac

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https://www.readbyqxmd.com/read/27465213/comparison-of-isoflurane-and-sevoflurane-in-cardiac-surgery-a-randomized-non-inferiority-comparative-effectiveness-trial
#1
Philip M Jones, Daniel Bainbridge, Michael W A Chu, Philip S Fernandes, Stephanie A Fox, Ivan Iglesias, Bob Kiaii, Ronit Lavi, John M Murkin
PURPOSE: Volatile anesthetics possess cardioprotective properties, but it is unknown if the cardioprotective effects extend equally to all members of the class. Although sevoflurane is a relatively newer anesthetic than isoflurane, its introduction into practice was not preceded by a head-to-head comparison with isoflurane in a trial focusing on clinically important outcomes. Our objective was to determine whether sevoflurane was non-inferior to isoflurane on a clinically important primary outcome in a heterogeneous group of adults undergoing cardiac surgery...
October 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/26900382/evidence-based-guideline-treatment-of-convulsive-status-epilepticus-in-children-and-adults-report-of-the-guideline-committee-of-the-american-epilepsy-society
#2
Tracy Glauser, Shlomo Shinnar, David Gloss, Brian Alldredge, Ravindra Arya, Jacquelyn Bainbridge, Mary Bare, Thomas Bleck, W Edwin Dodson, Lisa Garrity, Andy Jagoda, Daniel Lowenstein, John Pellock, James Riviello, Edward Sloan, David M Treiman
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant treatment of children and adults with convulsive status epilepticus and use this analysis to develop an evidence-based treatment algorithm. DATA SOURCES: Structured literature review using MEDLINE, Embase, Current Contents, and Cochrane library supplemented with article reference lists...
January 2016: Epilepsy Currents
https://www.readbyqxmd.com/read/26025024/loss-of-function-mutations-in-nnt-are-associated-with-left-ventricular-noncompaction
#3
Matthew N Bainbridge, Erica E Davis, Wen-Yee Choi, Amy Dickson, Hugo R Martinez, Min Wang, Huyen Dinh, Donna M Muzny, Ricardo Pignatelli, Nicholas Katsanis, Eric Boerwinkle, Richard A Gibbs, John L Jefferies
BACKGROUND: Left ventricular noncompaction (LVNC) is an autosomal-dominant, genetically heterogeneous cardiomyopathy with variable severity, which may co-occur with cardiac hypertrophy. METHODS AND RESULTS: Here, we generated whole exome sequence data from multiple members from 5 families with LVNC. In 4 of 5 families, the candidate causative mutation segregates with disease in known LVNC genes MYH7 and TPM1. Subsequent sequencing of MYH7 in a larger LVNC cohort identified 7 novel likely disease causing variants...
August 2015: Circulation. Cardiovascular Genetics
https://www.readbyqxmd.com/read/25975598/early-extubation-and-fast-track-management-of-off-pump-cardiac-patients-in-the-intensive-care-unit
#4
Daniel Bainbridge, Davy C Cheng
Off-pump surgery was the original approach to treating patients with cardiac disease in the era before cardiopulmonary bypass. With the advent and refinement of cardiopulmonary bypass, the use of this technique fell out of favor and was quickly surpassed by on-pump techniques. However, the limitations of bypass surgery, especially for coronary artery bypass procedures, was still significant, leading to renewed interest in this technique. Postoperative care for off-pump coronary artery bypass (OPCAB) surgery presents both a challenge and opportunity to the intensivist...
June 2015: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/25920902/salvaging-catastrophe-in-transcatheter-aortic-valve-implantation-rehearsal-preassigned-roles-and-emergency-preparedness
#5
REVIEW
Derrick Y Tam, Philip M Jones, Bob Kiaii, Pantelis Diamantouros, Patrick Teefy, Daniel Bainbridge, Andrew Cleland, Philip Fernandes, Michael W A Chu
PURPOSE: Emergency rescue plans for acute complications during transcatheter aortic valve implantation (TAVI) commonly include cardiopulmonary resuscitation, femoro-femoral cardiopulmonary bypass (CPB), and hemodynamic stabilization before definitive intervention is achieved. Nevertheless, most cases of emergency resuscitation remain chaotic and disorganized and often take longer than necessary, even in experienced centres. We sought to determine which factors and procedures may be associated with improved patient outcomes when emergencies arise during TAVI...
August 2015: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/25857628/patient-adaptive-maximal-resolution-magnetic-resonance-myocardial-stress-perfusion-imaging
#6
David P Ripley, Adam K McDiarmid, Ananth Kidambi, Akhlaque Uddin, Peter P Swoboda, Tarique A Musa, Bara Erhayiem, Gavin J Bainbridge, John P Greenwood, Sven Plein, David M Higgins
PURPOSE: To demonstrate the feasibility of an automatic adaptive acquisition sequence. Magnetic resonance perfusion pulse sequences often leave potential acquisition time unused in patients with lower heart-rates (HR) and smaller body size. MATERIALS AND METHODS: A perfusion technique was developed that automatically adapts to HR and field-of-view by maximizing in-plane spatial resolution while maintaining temporal resolution every cardiac cycle. Patients (n = 10) and volunteers (n = 10) were scanned with both a standard resolution and adaptive method...
October 2015: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/25479266/extreme-respiratory-sinus-arrhythmia-in-response-to-superimposed-head-down-tilt-and-deep-breathing
#7
Jeffrey R Baden, Maria Abrosimova, Lindsey M Boulet, Michael M Tymko, Jamie R Pfoh, Rachel J Skow, Trevor A Day
BACKGROUND: Respiratory sinus arrhythmia (RSA) is characterized by normal fluctuations in heart rate in phase with the respiratory cycle. There are many proposed mechanisms underlying the RSA phenomenon, including respiratory-induced cardiac loading (i.e., Bainbridge reflex), arterial baroreflex activation, vagal feedback from pulmonary stretch receptors, and central neural mechanisms. It is currently unclear to what extent these mechanisms are responsible for eliciting RSA in humans, particularly in response to stressors...
December 2014: Aviation, Space, and Environmental Medicine
https://www.readbyqxmd.com/read/25440276/unilateral-postoperative-pulmonary-edema-after-minimally-invasive-cardiac-surgical-procedures-a-case-control-study
#8
Mark P Tutschka, Daniel Bainbridge, Michael W A Chu, Bob Kiaii, Philip M Jones
BACKGROUND: Unilateral postoperative pulmonary edema is an underreported adverse event after a minimally invasive cardiac surgical procedure that combines right minithoracotomy with cardiopulmonary bypass. We sought to characterize its incidence, risk factors, and morbidity. METHODS: We conducted a retrospective case-control study of all cardiac surgical procedures that combined right-sided minithoracotomy with cardiopulmonary bypass at our institution over 8 consecutive years...
January 2015: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/25143415/development-of-our-tavi-protocol-for-emergency-initiation-of-cardiopulmonary-bypass
#9
P Fernandes, A Cleland, D Bainbridge, P M Jones, M W A Chu, B Kiaii
All transcatheter aortic valve implantation (TAVI) cases are done in our hybrid operating room with a multidisciplinary team and a primed cardiopulmonary bypass (CPB) circuit on pump stand-by. We decided that we would resuscitate all patients undergoing a TAVI procedure via a transfemoral, transapical or transaortic approach, if required. Perfusion plays an essential role in providing rescue CPB for patient salvage when catastrophic complications occur. To coordinate the multidisciplinary effort, we have developed a written safety checklist that assigns a pre-determined role for team members for the rapid sequence initiation of CPB...
January 2015: Perfusion
https://www.readbyqxmd.com/read/24922925/129%C3%A2-automatic-maximal-resolution-heart-rate-adaptive-stress-perfusion-imaging-cardiovascular-magnetic-resonance-study-at-3-0t
#10
David Ripley, David Higgins, Adam McDiarmid, Gavin Bainbridge, Akhlaque Uddin, Ananth Kidambi, John Greenwood, Sven Plein
INTRODUCTION: Myocardial perfusion cardiovascular magnetic resonance (CMR) with vasodilator stress has high diagnostic accuracy for the detection of coronary artery disease (CAD). Current CMR perfusion pulse sequences use fixed acquisition parameters designed to acquire at least three slices heart beat and optimised for the heart rates that occur during pharmacological stress.In patients with lower heart rates, there can therefore be a significant amount of unused imaging time (Figure 1)...
June 2014: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/24522621/pre-procedural-fasting-for-coronary-interventions-is-it-time-to-change-practice
#11
MULTICENTER STUDY
Tahir Hamid, Qaiser Aleem, Yeecheng Lau, Ravi Singh, John McDonald, John E Macdonald, Sanjay Sastry, Sanjay Arya, Anthony Bainbridge, Telal Mudawi, Kanarath Balachandran
INTRODUCTION: Traditionally, patients are kept nil-per-os/nil-by-mouth (NPO/NBM) prior to invasive cardiac procedures, yet there exists neither evidence nor clear guidance about the benefits of this practice. OBJECTIVES: To demonstrate that percutaneous cardiac catheterisation does not require prior fasting. METHODS: The data source is a retrospective analysis of data registry of consecutive patients who underwent percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS) and stable angina at two district general hospitals in the UK with no on-site cardiac surgery services...
April 2014: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/23475331/surface-based-ct-tee-registration-of-the-aortic-root
#12
Pencilla Lang, Michael W A Chu, Dan Bainbridge, Gerard M Guiraudon, Douglas L Jones, Terry M Peters
Transcatheter aortic valve implantation (TAVI) is a minimally invasive alternative to conventional aortic valve replacement for severe aortic stenosis in high-risk patients in which a stent-based bioprosthetic valve is delivered into the heart via a catheter. TAVI relies largely on single-plane fluoroscopy for intraoperative navigation and guidance, which provides only gross imaging of anatomical structures. Inadequate imaging leading to suboptimal valve positioning contributes to many of the early complications experienced by TAVI patients, including valve embolism, coronary ostia obstruction, paravalvular leak, heart block, and secondary nephrotoxicity from excessive contrast use...
December 2013: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/23123995/augmented-reality-image-guidance-improves-navigation-for-beating-heart-mitral-valve-repair
#13
COMPARATIVE STUDY
Michael W A Chu, John Moore, Terry Peters, Daniel Bainbridge, David McCarty, Gerard M Guiraudon, Chris Wedlake, Pencilla Lang, Martin Rajchl, Maria E Currie, Richard C Daly, Bob Kiaii
OBJECTIVE: Emerging off-pump beating heart valve repair techniques offer patients less invasive alternatives for mitral valve (MV) repair. However, most of these techniques rely on the limited spatial and temporal resolution of transesophageal echocardiography (TEE) alone, which can make tool visualization and guidance challenging. METHODS: Using a magnetic tracking system and integrated sensors, we created an augmented reality (AR) environment displaying virtual representations of important intracardiac landmarks registered to biplane TEE imaging...
July 2012: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/22998717/perioperative-and-anaesthetic-related-mortality-in-developed-and-developing-countries-a-systematic-review-and-meta-analysis
#14
REVIEW
Daniel Bainbridge, Janet Martin, Miguel Arango, Davy Cheng
BACKGROUND: The magnitude of risk of death related to surgery and anaesthesia is not well understood. We aimed to assess whether the risk of perioperative and anaesthetic-related mortality has decreased over the past five decades and whether rates of decline have been comparable in developed and developing countries. METHODS: We did a systematic review to identify all studies published up to February, 2011, in any language, with a sample size of over 3000 that reported perioperative mortality across a mixed surgical population who had undergone general anaesthesia...
September 22, 2012: Lancet
https://www.readbyqxmd.com/read/22885466/hybrid-access-to-atria-via-the-guiraudon-universal-cardiac-introducer-for-arrhythmia-ablation-after-total-cavopulmonary-derivation
#15
Gérard M Guiraudon, Douglas L Jones, Daniel Bainbridge, Laurence Cohen, Yves Lecompte, Françoise Hidden-Lucet, Robert Frank, Alain Pavie
We report the first use of a new platform, the Guiraudon Universal Cardiac Introducer (GUCI), in humans for accessing the left atrium for catheter-based ablations in patients with resistant atrial arrhythmias after total cavopulmonary derivation. The GUCI was originally designed for intracardiac access for closed, beating instrumental intracardiac surgery.The patient was a 29-year-old man with problematic atrial arrhythmias resistant to antiarrhythmic drugs because of severe uncontrolled bradycardia and because his pacemaker was explanted for infection...
May 2012: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/22458286/assessing-the-immediate-and-sustained-effectiveness-of-circular-epicardial-surgical-ligation-of-the-left-atrial-appendage
#16
Corey Adams, Daniel Bainbridge, Aashish Goela, Ian Ross, Bob Kiaii
BACKGROUND/AIM: Obliterating the left atrial appendage from systemic circulation in patients with atrial fibrillation has been proposed to reduce thromboembolic events. The goal of this study was to assess the effectiveness of a circular method of epicardial surgical ligation in obliterating the left atrial appendage and maintaining sustained exclusion. METHODS: Patients with permanent atrial fibrillation and an indication for elective cardiac surgery were enrolled...
March 2012: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/22437639/augmented-reality-image-guidance-during-off-pump-mitral-valve-replacement-through-the-guiraudon-universal-cardiac-introducer
#17
Gerard M Guiraudon, Douglas L Jones, Daniel Bainbridge, Cristian Linte, Danielle Pace, John Moore, Christopher Wedlake, Pencilla Lang, Terry M Peters
OBJECTIVE: : We report our experience with ultrasound augmented reality (US-AR) guidance for mitral valve prosthesis (MVP) implantation in the pig using off-pump, closed, beating intracardiac access through the Guiraudon Universal Cardiac Introducer attached to the left atrial appendage. METHODS: : Before testing US-AR guidance, a feasibility pilot study on nine pigs was performed using US alone. US-AR guidance, tested on a heart phantom, was subsequently used in three pigs (∼65 kg) using a tracked transesophageal echocardiography probe, augmented with registration of a 3D computed tomography scan, and virtual representation of the MVP and clip-delivering tool (Clipper); three pigs were used to test feature-based registration...
November 2010: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/22437167/off-pump-positioning-of-a-conventional-aortic-valve-prosthesis-through-the-left-ventricular-apex-with-the-universal-cardiac-introducer-under-sole-ultrasound-guidance-in-the-pig
#18
Gerard M Guiraudon, Douglas L Jones, Daniel Bainbridge, Terence M Peters
OBJECTIVE: : To test an alternative to catheter and open-heart techniques, by documenting the feasibility of implanting an unmodified mechanical aortic valve (AoV) in the off pump, beating heart using the universal cardiac introducer (UCI) attached to the left ventricular (LV) apex. METHODS: : In six pigs, the LV apex was exposed by a median sternotomy. The UCI was attached to the apex. A 12-mm punching tool (punch), introduced through the UCI, was used to create a cylindrical opening through the apex...
September 2009: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/22436899/off-pump-atrial-septal-defect-closure-using-the-universal-cardiac-introducer%C3%A2-creation-of-models-of-atrial-septal-defects-in-the-pig-access-and-surgical-technique
#19
Gerard M Guiraudon, Douglas L Jones, Daniel Bainbridge, John T Moore, Chris Wedlake, Cristian Linte, Andrew Wiles, Terry M Peters
OBJECTIVE: : Optimal atrial septal defect (ASD) closure should combine off-pump techniques with the effectiveness and versatility of open-heart techniques. We report our experience with off-pump ASD closure using the Universal Cardiac Introducer (UCI) in a porcine model. The goal was to create an ASD over the fossa ovale (FO) and position a patch over the ASD under ultrasound (US) imaging and augmented virtual reality guidance. METHODS: : An US probe (tracked with a magnetic tracking system) was positioned into the esophagus (transesophageal echocardiographic probe) for real-time image-guidance...
January 2009: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/22436709/investigating-perioperative-heart-migration-during-robot-assisted-coronary-artery-bypass-grafting-interventions
#20
Cristian A Linte, Daniel S Cho, Chris Wedlake, John Moore, Elvis Chen, Daniel Bainbridge, Rajni Patel, Terry Peters, Bob B Kiaii
OBJECTIVE: : For robot-assisted coronary artery bypass graft interventions, surgeons typically use a preoperative thoracic computed tomography scan of the patient to plan the procedure. However, the cardiac anatomy is prone to changes induced perioperatively in the effort to access the heart and surgical targets, which, in turn, may invalidate the initial plan. This article presents a method to estimate the perioperative heart migration, information which can be further exploited to refine the preoperative surgical plan...
September 2011: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
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