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https://www.readbyqxmd.com/read/28080212/heterogeneity-of-carbapenem-resistance-mechanisms-among-gram-negative-pathogens-in-lebanon-results-of-the-first-cross-sectional-countrywide-study
#1
Dalal Hammoudi Halat, Carole Ayoub Moubareck, Dolla Karam Sarkis
Carbapenem-resistant Gram-negative pathogens have progressively disseminated to different countries worldwide, presenting a serious public health concern. The aims of this study were to determine the prevalence of carbapenem resistance in Gram-negative bacteria in Lebanon, to elucidate molecular mechanisms, and to identify genetic relatedness of incriminated strains. Carbapenem nonsusceptible Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas were collected from 11 Lebanese hospitals in 2012. Antimicrobial susceptibility was assessed with phenotypic tests, genes encoding carbapenemases were screened via PCR-sequencing, and genetic relatedness was examined by PGFE and ERIC-PCR...
January 12, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28069124/combined-microplate-abts-and-hplc-abts-analysis-of-tomato-and-pepper-extracts-reveals-synergetic-and-antagonist-effects-of-their-lipophilic-antioxidative-components
#2
Julie Le Grandois, Delphine Guffond, Erwann Hamon, Eric Marchioni, Dalal Werner
The antioxidant capacity of 9 pure lipophilic compounds was examined by microplate-ABTS and HPLC-ABTS, using similar experimental conditions. Results obtained showed that HPLC-ABTS method can be used for a rapid determination of individual antioxidant capacity of compounds in standard solutions or complex mixtures. The application of both methods to real lipophilic extracts from tomato (Solanum lycopersicum L.), green and red peppers (Capsicum annuum) reveals possible interactions between antioxidants. Thus, synthetic mixtures of two compounds identified in tomato and peppers were measured using microplate-ABTS and HPLC-ABTS...
May 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28066026/response-to-letter-to-editor-internet-addiction-disorder-hype-a-myth
#3
P K Dalal, Debasish Basu
No abstract text is available yet for this article.
July 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28066005/metabolic-syndrome-and-central-obesity-in-depression-a-cross-sectional-study
#4
Anju Agarwal, Manu Agarwal, Kabir Garg, Pronob Kumar Dalal, Jitendra Kumar Trivedi, J S Srivastava
INTRODUCTION: The current epidemiological data and meta-analyses indicate a bidirectional association between depression and metabolic syndrome (MetS). AIMS: To assess the prevalence of metabolic syndrome and obesity in drug naïve patients (in current episode) having Recurrent Major Depressive Disorder and Bipolar Depression. METHOD: This was a single point cross sectional observational study that involved administration of diagnostic and assessment tools and blood investigations...
July 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28058213/face-transplantation-anesthetic-challenges
#5
REVIEW
Aparna Dalal
Face transplantation is a complex vascular composite allotransplantation (VCA) surgery. It involves multiple types of tissue, such as bone, muscles, blood vessels, nerves to be transferred from the donor to the recipient as one unit. VCAs were added to the definition of organs covered by the Organ Procurement and Transplantation Network Final Rule and National Organ Transplant Act. Prior to harvest of the face from the donor, a tracheostomy is usually performed. The osteotomies and dissection of the midface bony skeleton may involve severe hemorrhagic blood loss often requiring transfusion of blood products...
December 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/28058211/organ-transplantation-and-drug-eluting-stents-perioperative-challenges
#6
REVIEW
Aparna Dalal
Patients listed for organ transplant frequently have severe coronary artery disease (CAD), which may be treated with drug eluting stents (DES). Everolimus and zotarolimus eluting stents are commonly used. Newer generation biolimus and novolimus eluting biodegradable stents are becoming increasingly popular. Patients undergoing transplant surgery soon after the placement of DES are at increased risk of stent thrombosis (ST) in the perioperative period. Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor such as clopidogrel, prasugrel and ticagrelor is instated post stenting to decrease the incident of ST...
December 24, 2016: World Journal of Transplantation
https://www.readbyqxmd.com/read/28052162/consumer-preferences-and-online-comparison-tools-used-to-select-a-surgeon
#7
Justin B Ziemba, Mohamad E Allaf, Dalal Haldeman
No abstract text is available yet for this article.
January 4, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28051045/meckel-s-diverticulum-in-children-our-12-year-experience
#8
Kamal Nain Rattan, Jasbir Singh, Poonam Dalal, Ananta Rattan
BACKGROUND: Meckel's diverticulum (MD) is the one of the most common congenital malformation of gastrointestinal tract and has varied clinical presentations. We are presenting here our 12-year experiences with MD in children at tertiary care hospital in North India. It highlights the fact that isolated gangrene of MD can occur, and it is associated with increased morbidity. MATERIALS AND METHODS: This retrospective study is conducted by analysing the medical records of the patients who were operated for MD in the last 12 years in paediatric surgery department at our hospital...
October 2016: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/28050106/glanzmann-thrombasthenia-in-a-child-manifesting-after-dengue-infection
#9
Safal Muhammed, S S Dalal, K M Adhikari, Sheila S Mathai
No abstract text is available yet for this article.
December 2016: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28046112/correction-assessing-progress-impact-and-next-steps-in-rolling-out-voluntary-medical-male-circumcision-for-hiv-prevention-in-14-priority-countries-in-eastern-and-southern-africa-through-2014
#10
Katharine Kripke, Emmanuel Njeuhmeli, Julia Samuelson, Melissa Schnure, Shona Dalal, Timothy Farley, Catherine Hankins, Anne G Thomas, Jason Reed, Peter Stegman, Naomi Bock
[This corrects the article DOI: 10.1371/journal.pone.0158767.].
2017: PloS One
https://www.readbyqxmd.com/read/28038722/management-standards-for-stable-coronary-artery-disease-in-india
#11
Sundeep Mishra, Saumitra Ray, Jamshed J Dalal, J P S Sawhney, S Ramakrishnan, Tiny Nair, S S Iyengar, V K Bahl
Coronary artery disease (CAD) is one of the important causes of cardiovascular morbidity and mortality globally, giving rise to more than 7 million deaths annually. An increasing burden of CAD in India is a major cause of concern with angina being the leading manifestation. Stable coronary artery disease (SCAD) is characterised by episodes of transient central chest pain (angina pectoris), often triggered by exercise, emotion or other forms of stress, generally triggered by a reversible mismatch between myocardial oxygen demand and supply resulting in myocardial ischemia or hypoxia...
December 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/28038451/androgen-receptor-transcriptionally-regulates-semaphorin-3c-in-a-gata2-dependent-manner
#12
Kevin J Tam, Kush Dalal, Michael Hsing, Chi Wing Cheng, Shahram Khosravi, Parvin Yenki, Charan Tse, James W Peacock, Aishwariya Sharma, Yan Ting Chiang, Yuzhuo Wang, Artem Cherkasov, Paul S Rennie, Martin E Gleave, Christopher J Ong
The androgen receptor (AR) is a member of the nuclear receptor superfamily of transcription factors and is central to prostate cancer (PCa) progression. Ligand-activated AR engages androgen response elements (AREs) at androgen-responsive genes to drive the expression of gene batteries involved in cell proliferation and cell fate. Understanding the transcriptional targets of the AR has become critical in apprehending the mechanisms driving treatment-resistant stages of PCa. Although AR transcription regulation has been extensively studied, the signaling networks downstream of AR are incompletely described...
December 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/28027142/antiretroviral-drugs
#13
Kavitha S Dalal, Mary Barna Bridgeman
No abstract text is available yet for this article.
January 2017: Nursing
https://www.readbyqxmd.com/read/28017373/mutations-in-ebf3-disturb-transcriptional-profiles-and-cause-intellectual-disability-ataxia-and-facial-dysmorphism
#14
Frederike Leonie Harms, Katta M Girisha, Andrew A Hardigan, Fanny Kortüm, Anju Shukla, Malik Alawi, Ashwin Dalal, Lauren Brady, Mark Tarnopolsky, Lynne M Bird, Sophia Ceulemans, Martina Bebin, Kevin M Bowling, Susan M Hiatt, Edward J Lose, Michelle Primiano, Wendy K Chung, Jane Juusola, Zeynep C Akdemir, Matthew Bainbridge, Wu-Lin Charng, Margaret Drummond-Borg, Mohammad K Eldomery, Ayman W El-Hattab, Mohammed A M Saleh, Stéphane Bézieau, Benjamin Cogné, Bertrand Isidor, Sébastien Küry, James R Lupski, Richard M Myers, Gregory M Cooper, Kerstin Kutsche
From a GeneMatcher-enabled international collaboration, we identified ten individuals affected by intellectual disability, speech delay, ataxia, and facial dysmorphism and carrying a deleterious EBF3 variant detected by whole-exome sequencing. One 9-bp duplication and one splice-site, five missense, and two nonsense variants in EBF3 were found; the mutations occurred de novo in eight individuals, and the missense variant c.625C>T (p.Arg209Trp) was inherited by two affected siblings from their healthy mother, who is mosaic...
January 5, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28005278/igg4-related-disease-and-lymphocyte-variant-hypereosinophilic-syndrome-a-comparative-case-series
#15
Mollie N Carruthers, Sujin Park, Graham W Slack, Bakul I Dalal, Brian F Skinnider, David F Schaeffer, Jan P Dutz, Joanna K Law, Fergal Donnellan, Vladimir Marquez, Michael Seidman, Patrick C Wong, Andre Mattman, Luke Y C Chen
OBJECTIVE: To compare the clinical and laboratory features of IgG4-related disease (IgG4-RD) and lymphocyte variant-hypereosinophilic syndrome (L-HES), two rare diseases that often present with lymphadenopathy, gastrointestinal symptoms, eosinophilia and elevated immunoglobulins/IgE. METHOD: Comparative case series of 31 IgG4-RD and 13 L-HES patients. RESULTS: Peripheral blood eosinophilia was present in 8/31 IgG4-RD patients compared to 13/13 L-HES patients (median eosinophils 0...
December 22, 2016: European Journal of Haematology
https://www.readbyqxmd.com/read/28004450/cross-sectional-study-to-assess-the-need-to-commence-opportunistic-screening-of-women-for-cervical-cancer-presenting-with-sexually-transmitted-disease-in-western-india
#16
Mihir P Rupani, Ajay B Pawar, Raj Kumar Bansal, Malati Dalal, Ashvin Vachhani, Khushali D Parikh
This study examines the prevalence of suspected cervical cancer (established through the use of visual inspection with Lugol's Iodine - VILI) among outpatients attending Surat Municipal Institute of Medical Education & Research Hospital, India. A cross-sectional study was conducted on 356 patients; 178 with an established sexually transmitted disease (STD) and 178 patients without. Patients with positive results were investigated with cervical biopsy; out of 356 patients, 21.91% patients with STD and 12.35% patients without STD tested positive for VILI respectively (p = ...
December 22, 2016: European Journal of Cancer Care
https://www.readbyqxmd.com/read/28003904/a-case-of-deep-vein-thrombosis-and-intracranial-sinus-thrombosis-possible-rare-complications-of-childhood-abdominal-tuberculosis
#17
Geeta Gathwala, Poonam Dalal, Virender Gehlawat, Jasbir Singh, Vandana Arya
Severe pulmonary tuberculosis (TB) complicated by deep vein thrombosis (DVT) in adults has been reported previously in the medical literature; however, childhood extrapulmonary TB complicated by DVT is rare. We report a 13-year-old girl who presented to the Department of Pediatrics at the Postgraduate Institute of Medical Sciences in Rohtak, India, in 2012 with abdominal TB complicated by DVT and intracranial sinus thrombosis. She was treated with a course of four antitubercular drugs and short-term anticoagulation therapy with a positive outcome over the next six months...
November 2016: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/27997983/validation-of-international-classification-of-disease-ninth-revision-codes-for-atopic-dermatitis
#18
Derek Y Hsu, Prarthana Dalal, Kimberly A Sable, Nihal Voruganti, Beatrice Nardone, Dennis West, Jonathan I Silverberg
BACKGROUND: Evaluation of large-scale data sets is needed to better understand the epidemiology, cost and burden of atopic dermatitis (AD). We sought to validate the use of ICD-9-CM codes for identifying AD. METHODS: Patients from a large metropolitan quaternary care medical center with a diagnostic code of either 691.8 (AD) or 692.9 (eczema and contact dermatitis) were queried. Medical records were reviewed for demographics, Hanifin & Rajka (H&R) and United Kingdom Working Party (UKWP) criteria...
December 20, 2016: Allergy
https://www.readbyqxmd.com/read/27997206/nanomolar-antimalarial-agents-against-chloroquine-resistant-plasmodium-falciparum-from-medicinal-plants-and-their-structure-activity-relationships
#19
Bin Zhou, Yan Wu, Seema Dalal, Emilio F Merino, Qun-Fang Liu, Cheng-Hui Xu, Tao Yuan, Jian Ding, David G I Kingston, Maria B Cassera, Jian-Min Yue
Inspired by the discovery of the antimalarial drug artemisinin from a traditional Chinese medicine (TCM), a natural product library of 44 lindenane-type sesquiterpenoids was assessed for activities against the Dd2 chloroquine-resistant strain of the malaria parasite Plasmodium falciparum. These compounds were mainly isolated from plants of the Chloranthus genus, many species of which are named "Sikuaiwa" in TCM and have long been used to treat malaria. The compounds consisted of 41 sesquiterpenoid dimers and three monomers, including the 12 new dimers 1-12 isolated from Chloranthus fortunei...
December 20, 2016: Journal of Natural Products
https://www.readbyqxmd.com/read/27994788/results-of-single-staged-posterior-decompression-and-circumferential-fusion-using-a-transpedicular-approach-to-correct-a-kyphotic-deformity-due-to-thoracolumbar-spinal-tuberculosis
#20
Shaival Dalal, Jayprakash Modi, Shardul Soman, Harshil Patel, Shrikant Dhanani
STUDY DESIGN: This is a prospective study. PURPOSE: The aim of this study was to investigate the results of single-staged posterior decompression and circumferential fusion using a transpedicular approach to correct a kyphotic deformity due to thoracolumbar spinal tuberculosis. OVERVIEW OF LITERATURE: Surgical management is frequently an imperative choice to achieve spinal decompression and deformity correction due to tuberculosis to relieve pain, improve neurology, and reconstruct the spine stability...
December 2016: Asian Spine Journal
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