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coronary artery ectasia

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https://www.readbyqxmd.com/read/28079513/high-dose-aspirin-for-kawasaki-disease-outdated-myth-or-effective-aid
#1
Gil Amarilyo, Yael Koren, Dafna Brik Simon, Maskit Bar-Meir, Hilla Bahat, Mona Hanna Helou, Amir Mendelson, Nofar Hezkelo, Gabriel Chodick, Yackov Berkun, Eli Eisenstein, Yonatan Butbul Aviel, Galia Barkai, Yoav Bolkier, Shai Padeh, Riva Brik, Phillip J Hashkes, Liora Harel, Yosef Uziel
OBJECTIVES: To compare the efficacy and safety of intravenous immunoglobulin (IVIG) plus high-dose aspirin (HDA) vs. IVIG plus low-dose aspirin (LDA) for the treatment of Kawasaki disease, with an emphasis on coronary artery outcomes. METHODS: This study was a retrospective, medical record review of paediatric patients with Kawasaki disease comparing 6 centres that routinely used HDA for initial treatment and 2 that used LDA in 2004-2013. Treatment response and adverse events were compared...
January 5, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27941711/recurrent-acute-myocardial-infarction-in-a-patient-with-severe-coronary-artery-ectasia-implication-of-antithrombotic-therapy
#2
Tomoko Tomioka, Satoshi Takeuchi, Yoshitaka Ito, Hiroki Shioiri, Jiro Koyama, Kanichi Inoue
BACKGROUND Acute myocardial infarction (AMI) can be caused not only by plaque rupture/erosion, but also by many other mechanisms. Thromboembolism due to atrial fibrillation and coronary thrombosis due to coronary artery ectasia are among the causes. Here we report on a case of recurrent myocardial infarction with coronary artery ectasia. CASE REPORT Our case was a 78-year-old woman with hypertension. Within a one-month interval, she developed AMI twice at the distal portion of her right coronary artery along with coronary artery ectasia...
December 12, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27885846/big-endothelin-1-level-is-a-useful-marker-for-predicting-the-presence-of-isolated-coronary-artery-ectasia
#3
Yao Wang, Yan Zhang, Cheng-Gang Zhu, Yuan-Lin Guo, Qiao-Juan Huang, Na-Qiong Wu, Ying Gao, Ping Qing, Geng Liu, Qian Dong, Jian-Jun Li
CONTEXT: Endothelin-1(ET-1) has been implicated in coronary artery disease (CAD) and may be associated with coronary artery ectasia (CAE). OBJECTIVE: To clarify the relationship between big ET-1 and isolated CAE. METHODS: We measured big ET-1 with ELISA in 216 patients (CAE, n = 72; CAD, n = 72; normal, n = 72) and evaluated the link with isolated CAE. RESULTS: The level of plasma big ET-1 was significantly higher in patients with isolated CAE (p < 0...
December 12, 2016: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/27879468/relationship-between-plasma-levels-of-soluble-cd40-ligand-and-the-presence-and-severity-of-isolated-coronary-artery-ectasia
#4
Cem Ozde, Ahmet Korkmaz, Harun Kundi, Ersan Oflar, Ismail Ungan, Vusal Xankisi, Nilhan Nurlu
OBJECTIVE: We aimed to investigate whether soluble CD40 ligand (CD40L) levels are higher in patients with isolated coronary artery ectasia (CAE) compared to patients with angiographically normal coronary arteries and those with stable coronary artery disease (CAD). MATERIALS AND METHODS: In all, 55 patients with isolated CAE without stenosis, 55 with stable CAD, and 55 control participants with angiographically normal coronary arteries were included. The CAE severity was determined according to the Markis classification...
November 21, 2016: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/27866019/dysregulated-fatty-acid-metabolism-in-coronary-ectasia-an-extended-lipidomic-analysis
#5
Usama Boles, Rui Climaco Pinto, Santosh David, Abdullah S Abdullah, Michael Y Henein
BACKGROUND: Coronary artery ectasia (CAE) is not an uncommon clinical condition, which could be associated with adverse outcome. The exact pathophysiology of the disease is poorly understood and is commonly interpreted as a variant of atherosclerosis. In this study, we sought to undertake lipidomic profiling of a group of CAE patients in an attempt to achieve better understanding of its disturbed metabolism. METHODS: Untargeted lipid profiling and complementary modelling strategies were employed to compare serum samples from 16 patients with CAE (mean age 63...
February 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/27843802/coronary-ectasia-in-a-man-on-breast-cancer-therapy-presenting-with-acute-coronary-syndrome
#6
Dana C Johnson, Luay Rifai, Parag V Patel
Limited data exist on the association between breast cancer treatments and coronary artery disease anatomy, particularly in males. We describe an unusual case of diffuse coronary ectasia in a man with breast cancer presenting with acute coronary syndrome (ACS). A 66-year-old man with breast cancer on paclitaxel, tamoxifen, and carboplatin chemotherapy regimen, presents with new onset chest pain. Electrocardiogram reveals anterolateral ST-segment depressions and elevated troponin I level. Emergent angiography revealed grossly ectatic coronary arteries with a total thrombotic occlusion of the mid right coronary artery...
October 2016: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/27806720/kawasaki-disease-in-sicily-clinical-description-and-markers-of-disease-severity
#7
Maria Cristina Maggio, Giovanni Corsello, Eugenia Prinzi, Rolando Cimaz
BACKGROUND: Kawasaki disease (KD) is an acute systemic vasculitis of small and middle size arteries; 15-25 % of untreated patients and 5 % of patients treated with intravenous immunoglobulin (IVIG) develop coronary artery lesions (CAL). Many studies tried to find the most effective treatment in the management of resistant KD and to select the risk factors for CAL. Our data are assessed on children from west Sicily, characterized by a genetic heterogeneity. METHODS: We studied the clinical data of 70 KD Sicilian children (36 males: 51 %; 34 females: 49 %), analysed retrospectively, including: demographic and laboratory parameters; echocardiographic findings at diagnosis, at 2, 6 and 8 weeks, and at 1 year after the onset of the illness...
November 2, 2016: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/27785148/diffuse-coronary-artery-ectasia-in-a-patient-with-left-main-coronary-artery-trifurcation
#8
Jarosław Wasilewski, Piotr Desperak, Kamil Bujak, Jan Głowacki, Mariusz Gąsior
The term coronary ectasia is reserved to describe a diffuse dilatation of coronary artery segments that have a diameter that exceeds the size of normal adjacent coronary segments by 1.5 times. The occurrence of coronary artery ectasia (CAE) ranges from 3% to 8% in the group of patients undergoing coronary computed tomography angiography. The CAE is associated with traditional risk factors and often co-exists with coronary atherosclerosis, which suggests that ectasia may represent an advanced form of atherosclerosis...
September 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27779165/independent-prognostic-value-of-high-sensitivity-c-reactive-protein-in-patients-with-coronary-artery-ectasia
#9
Yintang Wang, Yang Wang, Shijie You, Hongjian Wang, Dong Yin, Kefei Dou, Weihua Song
BACKGROUND: Despite its severity, coronary artery ectasia (CAE) is still poorly understood. High-sensitivity C-reactive protein (hs-CRP) has been recognized as a prognostic factor in some cardiovascular diseases but not assessed in CAE. The aim of this observational study was to investigate the prognostic value of hs-CRP in CAE. METHODS: Our analysis evaluated the effect of the baseline hs-CRP on cardiovascular events (CVs) (cardiac death and nonfetal myocardial infarction) in consecutively enrolled stable CAE patients...
2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27739265/a-clinical-and-angiographic-profile-and-assessment-of-outcomes-in-coronary-artery-ectasias-single-centre-experience
#10
Rashmi Kerr, Cinosh Mathew, Ram Gopal Shahi, Rajneesh Calton
OBJECTIVE: To assess the clinical and angiographic profile of patients with coronary artery ectasias (CAE) and assess their outcomes. METHODS: One year retrospective and one year prospective study was carried out in the Department of Cardiology in CMC, Ludhiana from January 2011 to December 2012 on all patients undergoing coronary angiographies and each patient was followed up for 1 year. Their outcomes were noted and statistical analysis carried out. RESULTS: There were a total of 327 males (66...
June 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27733430/coronary-artery-ectasia-are-frequently-observed-in-patients-with-bicuspid-aortic-valves-with-and-without-dilatation-of-the-ascending-aorta
#11
Christine Meindl, Birgit Achatz, Deborah Huber, Andrea Baessler, Ute Hubauer, Christa Meisinger, Christian Hengstenberg, Jeanette Erdmann, Stefan Buchner, Lars Maier, Heribert Schunkert, Kurt Debl, Marcus Fischer
BACKGROUND: The presence of coronary artery ectasia (CAE) is influenced by genetic factors and related to the presence of aneurysms in other vascular beds. Bicuspid aortic valve (BAV) disease is frequently accompanied by ascending aortic aneurysm. Because the aortic valve and the proximal parts of the coronary arteries share a common embryonic origin, we hypothesized that CAE is associated with BAV disease. METHODS AND RESULTS: One hundred seventy-seven patients with suspected aortic valve disease (n=94 BAV, n=83 tricuspid aortic valve) underwent both cardiac magnetic resonance imaging and coronary angiography...
October 2016: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27629959/acute-coronary-syndrome-in-a-puerperal-patient-with-coronary-artery-ectasia-due-to-a-coronary-artery-fistula
#12
Taiji Okada, Akihiro Endo, Simpei Ito, Taku Nakamura, Takashi Sugamori, Nubuyuki Takahashi, Hiroyuki Yoshitomi, Kazuaki Tanabe
Coronary artery fistulas are rare and the feeding artery is ectatic and tortuous. It is not well-known whether coronary artery ectasia (CAE) is a risk factor of acute coronary syndrome (ACS) in the puerperal periods. A 40-year-old woman with a coronary artery fistula and an ectatic right coronary artery (RCA) had delivered twins. A month later, she had chest pain and coronary angiography revealed thrombogenesis in the RCA. She had no risk factors of cardiovascular disease or thrombogenesis. We should recognize that CAE is a risk factor for ACS in women in the perinatal and puerperal periods...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27609440/a-possible-mechanism-of-spontaneous-coronary-dissection-coronary-artery-ectasia
#13
Mutlu Vural, Ender Özal
No abstract text is available yet for this article.
September 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27607565/investigating-prevalence-and-pattern-of-long-term-cardiovascular-disorders-in-sulphur-mustard-exposed-victims-and-determining-proper-biomarkers-for-early-defining-monitoring-and-analysis-of-patients-feedback-on-therapy
#14
REVIEW
Behrad Darvishi, Yunes Panahi, Mostafa Ghanei, Leila Farahmand
Among the most readily existing chemical warfare agents, sulphur mustard (SM), also known as mustard gas, is the most commonly used agent owing to its ease of synthesis and stockpiling. Unprotected exposure mostly results in debilitation rather than lethal injuries, leaving an exposed victim incapacitated for days to even months. Although acute toxicity of sulphur mustard has been fairly established, the long-term post-exposure effects either chronic or short-term but significant are still evolving. A total of 30,000 Iranian victims of the Iran-Iraq imposed war have now - after 30 years - formed the key population demonstrating long-term effects from sulphur mustard exposure...
September 8, 2016: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27606147/hemophagocytosis-in-the-acute-phase-of-fatal-kawasaki-disease-in-a-4-month-old-girl
#15
Vehbi Doğan, Erhan Karaaslan, Samet Özer, Rüveyda Gümüşer, Resul Yılmaz
BACKGROUND: Kawasaki disease is a systemic vasculitis predominately affecting coronary arteries. Hemophagocytic lymphohistiocytosis can complicate the course of Kawasaki disease. Rare cases of secondary hemophagocytic lymphohistiocytosis occurring during the acute phase of Kawasaki disease have been reported. CASE REPORT: We report here a 4 month-old girl with diffuse coronary ectasia and secondary hemophagocytic lymphohistiocytosis occurring during the acute phase of incomplete Kawasaki disease...
July 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27598894/a-case-of-isolated-coronary-artery-ectasia-in-the-setting-of-chronic-inflamation-from-human-immunodeficiency-virus-infection
#16
Mark R Heckle, Raza Askari, Mohamed Morsy, Uzoma N Ibebuogu
Coronary artery ectasia also known as dilated coronopathy is a relatively rare finding that is most commonly associated with atherosclerosis. Several alternative reasons including congenital malformations and chronic inflammation have been identified as a cause of CAE. In this case, we discuss a 61-year-old male with postoperative chest pain who was found to have localized CAE in the absence of significant atherosclerosis. We also elucidate the recently proposed markers of chronic inflammation that might be associated with coronary artery ectasia...
July 2016: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/27569536/thiol-disulfide-homeostasis-a-new-insight-into-coronary-artery-ectasia
#17
Bartosz Hudzik, Mariusz Gąsior, Barbara Zubelewicz-Szkodzińska
No abstract text is available yet for this article.
October 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27568385/coronary-artery-aneurysm-differs-from-coronary-artery-ectasia-angiographic-characteristics-and-cardiovascular-risk-factor-analysis-in-patients-referred-for-coronary-angiography
#18
Yu Luo, Jiani Tang, Xu Liu, Jianping Qiu, Zi Ye, Yan Lai, Yian Yao, Jimin Li, Xiaodong Wang, Xuebo Liu
The differences in angiographic characteristics and cardiovascular (CV) risk factors between coronary artery aneurysm (CAA) and coronary artery ectasia (CAE) have not been compared systematically. Of 10 876 patients undergoing coronary angiography, patients with CAA (n = 85) and CAE (n = 51) were screened. The prevalence of CAA was greater than that of CAE (P < .05). The right coronary artery was the most involved (70.6%) in CAE compared with left circumflex (52.9%) and left anterior descending (41.2%). Coronary artery aneurysm coexisted with coronary artery disease (CAD) more frequently than CAE (P = ...
August 27, 2016: Angiology
https://www.readbyqxmd.com/read/27495054/role-of-gender-in-types-and-frequency-of-coronary-artery-aneurysm-and-ectasia
#19
Baktash Morrad, Huseyin Ugur Yazici, Yuksel Aydar, Cengiz Ovali, Aydin Nadir
This study aimed to evaluate the role of gender in types and frequency of coronary artery aneurysm and ectasia.We assessed retrospectively the angiography records of 6100 patients. At first, we mainly reviewed angiographic movies for the presence of coronary ectasia and/or aneurysm. Consequently, based on the number of the coronary artery involvement, the coronary ectasia and aneurysm were graded as mild if 1 coronary artery was involved and severe if 2 or more coronary arteries were involved. The location of ectasia and aneurysm was analyzed with respect to their isolated or combined location on various coronary arteries...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27476567/-annuloaortic-ectasia-associated-with-single-coronary-artery-and-ventricular-septal-defect-report-of-a-case
#20
Hideo Tsunemoto, Kazuhiro Yamaura
Single coronary artery is rear. Various combination anomalies have been reported in patients with this anomaly undergoing heart surgery. We report a case of annuloaortic ectasia combined with single coronary artery and ventricular septal defect. The patient was a 67-year-old man with exertional dyspnea. Coronary angiography and computed tomography revealed a single coronary artery. Aortography showed severe aortic regurgitation and dilatation of Valsalva sinus. Ultrasonic cardiography showed small ventricular septal defect at the membranous septum...
August 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
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