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coronary artery ectasia

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https://www.readbyqxmd.com/read/29788926/correlation-of-increased-corrected-timi-frame-counts-and-the-topographical-extent-of-isolated-coronary-artery-ectasia
#1
Wei Wu, Shuyang Zhang, Yuchao Guo, Ruifeng Liu, Zhujun Shen, Xueqing Zhu, Zhenyu Liu
BACKGROUND: The precise relationship between increased thrombolysis in myocardial infarction (TIMI) frame counts and the topographical extent of isolated coronary artery ectasia (CAE) has not been fully explained. New parameters of linear dimension (LD) and the estimated ectatic area (EEA) together with the diameter and ectasia ratio may be associated with the corrected TIMI frame count (CTFC) in isolated CAE patients. METHODS: The topographical parameters of ectatic coronary arteries and/or segments of 77 isolated CAE patients were consecutively studied...
May 22, 2018: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/29772448/molecular-and-cellular-insights-into-the-pathogenesis-of-coronary-artery-ectasia
#2
REVIEW
Selcuk Ozturk, Ertan Yetkin, Johannes Waltenberger
Coronary artery ectasia describes a local or diffuse dilatation of the epicardial coronary arteries. This review summarizes the molecular and cellular mechanisms involved in the pathogenesis of coronary artery ectasia. Better identification of the pathophysiologic steps will shed light into the clinical significance and may have direct implications for the management strategies of this disease. Additionally, understanding the underlying etiology may help to improve treatment modalities specific to coronary artery ectasia...
April 16, 2018: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/29768318/angiographic-characteristics-of-st-elevation-myocardial-infarction-patients-with-infarct-related-coronary-artery-ectasia-undergoing-primary-percutaneous-coronary-intervention
#3
Babak Geraiely, Mojtaba Salarifar, Mohammad Alidoosti, Seyedeh Hamideh Mortazavi
Coronary ectasia accounts for 0.3%-4.9% of patients undergoing coronary angiography. We conducted the present study to evaluate the angiographic characteristics of ST-elevation myocardial infarction (STEMI) patients with infarct-related coronary artery ectasia (IRAE) undergoing primary percutaneous coronary intervention. We evaluated 667 STEMI patients who were divided into 2 groups of IRAE (n = 81) and non-IRAE (n = 568). Preprocedural thrombolysis in myocardial infarction (TIMI) flow grade, postprocedural TIMI flow grade, thrombus burden grade, and TIMI frame count were then evaluated...
June 2018: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/29731349/coronary-artery-ectasia-an-independent-predictor-of-no-reflow-after-primary-pci-for-st-elevation-myocardial-infarction
#4
H C F Schram, V V Hemradj, R S Hermanides, E Kedhi, J P Ottervanger
BACKGROUND: The no-reflow phenomenon is a serious complication after primary percutaneous coronary intervention (PCI) for ST-elevation Myocardial Infarction (STEMI). Coronary artery ectasia (CAE) may increase the risk of no-reflow, however, only limited data is available on the potential impact of CAE. The aim of this study was to determine the potential association between CAE and no-reflow after primary PCI. METHODS: A case control study was performed based on a prospective cohort of STEMI patients from January 2000 to December 2011...
April 25, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29706554/-deferred-versus-immediate-stenting-in-patients-with-st-segment-elevation-myocardial-infarction-and-residual-large-thrombus-burden-reclassified-in-the-culprit-lesion
#5
Piero Custodio-Sánchez, Félix Damas-De Los Santos, Marco A Peña-Duque, Daniel Coutiño-Castelán, Eduardo Arias-Sánchez, Arturo Abundes-Velasco, Oscar Castro-Alvarado, Franklyn A Colon-Arias, Carlos Alvarenga-Fajardo, César Hernández-Fonseca, Erika Rodríguez-Barriga, Adolfo Hernández-Padilla
BACKGROUND: Reclassification of a large thrombus burden is an independent predictor of major adverse cardiac events and no-reflow in patients with ST- segment elevation myocardial infarction (STEMI). Patients with a greater residual thrombus burden have worse microvascular dysfunction and greater myocardial damage. METHODS: A retrospective analysis was performed on 833 STEMI patients who underwent primary percutaneous coronary intervention. The final residual thrombus burden was reclassified after the lesion was wired, and a thrombus aspiration or balloon dilatation was performed to restore and stabilise a thrombolysis in myocardial infarction (TIMI) 2-3 flow...
April 26, 2018: Archivos de Cardiología de México
https://www.readbyqxmd.com/read/29570178/predictors-of-intravenous-immunoglobulin-non-response-and-racial-disparities-in-kawasaki-disease
#6
Daniel E Clark, Kara J Denby, Laura M Kaufman, Mary-Margaret A Fill, Bhinnata Piya, Shanthi Krishnaswami, Christopher Fonnesbeck, Natasha Halasa
BACKGROUND: Kawasaki disease (KD) is the most common cause of acquired heart disease in American children. IVIG non-response is a known risk factor for cardiac sequelae. Previously reported risk factors for non-response include age, male sex, and laboratory abnormalities. We set out to identify additional risk factors for IVIG non-response in a racially diverse KD population. METHODS: We conducted a retrospective chart review at a referral center in the Southeastern United States of children meeting ICD-9 criteria for KD and being treated with IVIG...
March 19, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29564347/aneurysmal-coronary-artery-disease-an-overview
#7
REVIEW
Mohamed S ElGuindy, Ahmed M ElGuindy
Aneurysmal coronary artery disease (ACAD) comprises both coronary artery aneurysms (CAA) and coronary artery ectasia (CAE). The reported prevalence of ACAD varies widely from 0.2 to 10%, with male predominance and a predilection for the right coronary artery (RCA). Atherosclerosis is the commonest cause of ACAD in adults, while Kawasaki disease is the commonest cause in children and adolescents, as well as in the Far East. Most patients are asymptomatic, but when symptoms do exist, they are usually related to myocardial ischemia...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564344/cardiovascular-outcomes-following-kawasaki-disease-in-moscow-russia-a-single-center-experience
#8
Galina Lyskina, Olga Bockeria, Olga Shirinsky, Alena Torbyak, Anna Leontieva, Nina Gagarina, Anna Satyukova, Julia Kostina, Olga Vinogradova
Background: Awareness of Kawasaki disease (KD) is emerging in Russia but the diagnosis is still often missed. Methods: This is a retrospective study of 303 children with KD who received care at a single center in Moscow over the period from 2004 to 2016. Results: Overall, coronary artery aneurysms were documented in 91 (30,0%) of 303 patients and transient ectasia in 40 (13,2%). Intracoronary thrombi were found in 12 of 15 patients with giant aneurysms and in 3 patients with medium-sized aneurysms. Conclusion: The patients with KD in the Moscow region had typical features of the disease described in the literature but the proportion of patients with coronary artery aneurysms was higher than reported from other countries...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29468725/a-clinical-risk-score-to-identify-patients-at-high-risk-of-very-late-stent-thrombosis
#9
Thea C Godschalk, Marieke E Gimbel, Wouter W Nolet, Dionne J van Kessel, Giovanni Amoroso, Willem J Dewilde, Joanna J Wykrzykowska, Paul W Janssen, Thomas O Bergmeijer, Johannes C Kelder, Ton Heestermans, Jurriën M Ten Berg
OBJECTIVES: The aim of this study was to determine predictors of very late stent thrombosis (VLST; >1 year after stenting), and to evaluate whether addition of these predictors to the dual antiplatelet therapy (DAPT) score would improve the ability to identify patients at high risk of VLST who might benefit from DAPT. BACKGROUND: VLST is a severe complication of percutaneous coronary intervention (PCI). Extended knowledge about the predictors of VLST is needed to prevent this life-threatening complication...
April 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29404853/implantation-of-multiple-polytetrafluoroethylene-covered-stent-inside-drug-eluting-stent-to-rescue-purulent-coronary-artery-ectasia-with-giant-saccular-aneurysm
#10
Yusuke Namba, Toshiaki Yamanaka, Jun Ida, Takefumi Oka
A 79-year-old male with diabetes mellitus and old cerebral infarction was admitted to hospital due to fever and palpitation. Diagnosis of purulent pericarditis was established by pericardial effusion examination. The patient's general condition improved temporarily after drainage of the pericardial effusion. However, computed tomography demonstrated a saccular aneurysm arising from RCA have rapidly grown even larger, up to 63 × 51 mm on 7th hospital day. This indicated that the risk of rupture of the aneurysm was high...
February 5, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29339675/association-of-serum-prolidase-activity-in-patients-with-isolated-coronary-artery-ectasia
#11
Erdal Aktürk, Lütfü Aşkın, Hüseyin Nacar, M Hakan Taşolar, Serdar Türkmen, Mustafa Çetin, Mehmet Bozkurt
OBJECTIVE: Coronary artery ectasia (CAE) is defined as an angiographic enlargement of a portion of the coronary artery between 1.5 and 2 times the diameter of the adjacent normal coronary artery. It has been demonstrated that increased serum prolidase activity (SPA) is associated with increased collagen turnover. We aimed to analyze the relationship between CAE and serum SPA levels. METHODS: This study used a prospective case protocol design. A total of 40 consecutive patients with isolated right CAE and normal coronary arteries (23 men, 17 women; mean age, 62...
January 17, 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29337902/cytokine-disturbances-in-coronary-artery-ectasia-do-not-support-atherosclerosis-pathogenesis
#12
Usama Boles, Anders Johansson, Urban Wiklund, Zain Sharif, Santhosh David, Siobhan McGrory, Michael Y Henein
BACKGROUND: Coronary artery ectasia (CAE) is a rare disorder commonly associated with additional features of atherosclerosis. In the present study, we aimed to examine the systemic immune-inflammatory response that might associate CAE. METHODS: Plasma samples were obtained from 16 patients with coronary artery ectasia (mean age 64.9 ± 7.3 years, 6 female), 69 patients with coronary artery disease (CAD) and angiographic evidence for atherosclerosis (age 64.5 ± 8...
January 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29317980/a-history-of-kawasaki-disease-from-childhood-and-coronary-artery-ectasia-with-recurrent-st-elevation-myocardial-infarction-a-therapeutic-challenge
#13
Ashraf Abugroun, Daniel Vilchez, Osama Hallak, Anahita Shahrrava
Coronary artery ectasia (CAE) is an uncommon anomaly, usually found in 1.2-2% of patients undergoing coronary angiography, defined as a segment of the coronary artery that has a diameter of more than 1.5 times the normal adjacent segments. Atherosclerosis is considered as the cause of half of the CAE cases. We herein present a 65-year-old Asian male with past medical history of Kawasaki disease (KD) who developed recurrent episodes of inferior wall ST-elevation myocardial infarction (STEMI) despite treatment with dual antiplatelet therapy (DAPT)...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29317970/evaluation-of-the-tp-te-interval-qtc-and-p-wave-dispersion-in-patients-with-coronary-artery-ectasia
#14
Ronan Conlon, Richard Tanner, Santhosh David, Gabor Szeplaki, Joseph Galvin, John Keaney, Edward Keelan, Usama Boles
Background: Coronary artery ectasia (CAE) is defined as a diffuse dilatation of the diameter of the ectatic segment of the coronary artery, 1.5 times greater than that of the adjacent segment. The Tp-Te interval, P-wave and QTc dispersions are relatively new electrocardiographic markers associated with an increased risk of developing arrhythmias. Despite CAE increasing in prevalence in recent years, there is a sparsity of data available about its arrhythmogenic effect. The aim of the study was to evaluate QTc, P-wave dispersion and Tp-Te and Tp-Te/QT ratio in patients with CAE...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29246775/coronary-ectasia-in-amyloid-cardiomyopathy-and-neuropathy-due-to-the-transthyretin-mutation-c-323a-g
#15
Josef Finsterer, Claudia Stöllberger, Helmut Rauschka, Edmund Gatterer
BACKGROUND: atrial fibrillation(AF) is a frequent manifestation of cardiac involvement in genetic and wild-type transthyretin-related familial amyloidosis(TTR-FA). However, ectasia of coronary arteries and ablation for AF have not been reported in TTR-FA. METHODS AND RESULTS: A 65yo male developed progressive sensori-motor polyneuropathy since age 59y. At age 60y bifascicular block and myocardial thickening were recognised. At age 62y heart failure developed and work-up with cardiac MRI suggested amyloidosis but biopsy was non-informative...
March 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29181042/associations-between-coronary-artery-disease-aneurysm-and-ectasia
#16
Cengiz Ovalı, Baktash Morrad
Aim: Investigation the frequency and contribution of coronary artery aneurysm/ectasia in addition to their correlation with coronary artery disease (CAD). Material and methods: We retrospectively evaluated the coronary angiography records of 6500 adult consecutive patients, and 418 of them were met inclusion criteria and used in the present study. The CAD was defined as the presence of angiographic coronary stenosis of > 50% of the luminal diameter in no less than one of the epicardial coronary arteries...
September 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29115035/role-of-imaging-studies-in-kawasaki-disease
#17
Etsuko Tsuda, Manphool Singhal
Kawasaki disease is a medium vessel vasculitis which may be associated with coronary artery abnormalities. Recognition of these abnormalities depends upon various imaging modalities. While two-dimensional echocardiography remains the first line modality to identify coronary artery abnormalities, it is subject to several fallacies and is operator dependent. Computed tomography coronary angiography is rapidly emerging as a useful imaging modality for better characterization of dilatations, ectasia and aneurysms in the mid- and distal segments of coronary arteries...
January 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29106833/-coronary-ectasias-and-thrombosis
#18
M A Bouzid, H Benamer, X Halna du Fretay
Ectasias and coronary aneurysms are uncommon coronary artery diseases, can coexist and are poorly known. Their principal etiology in adults is coronary atherosclerosis. It has been suggested that these abnormalities would have poor prognosis and that slow flow could lead to in situ thrombosis and distal embolisation. However, ectasias and aneurysms are most often associated with coronary stenosis. We report a series of 47 cases of ectasias and coronary aneurysms with evaluation of the clinical and angiographic characteristics, the therapeutic choices and we review the literature concerning these lesions...
December 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29054186/isolated-coronary-artery-ectasia-clinical-angiographic-and-follow-up-characteristics
#19
Amit Malviya, Pravin K Jha, Animesh Mishra
BACKGROUND: Isolated Coronary artery ectasia (CAE) is considered an uncommon angiographic finding with varying patterns of presentation and carries significant morbidity burden to the patient. Our objective was to evaluate the prevalence of this condition, to analyse its clinical, angiographic, and follow up characteristics. PATIENTS AND METHODS: Coronary angiography was performed in 4950 patients from January 2009 to August 2014. The epidemiological, clinical, angiographic, and follow up characteristics of 52 patients with isolated CAE were examined...
September 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29051141/coronary-artery-ectasia-predicts-future-cardiac-events-in-patients-with-acute-myocardial-infarction
#20
Takahito Doi, Yu Kataoka, Teruo Noguchi, Tatsuhiro Shibata, Takahiro Nakashima, Shoji Kawakami, Kazuhiro Nakao, Masashi Fujino, Toshiyuki Nagai, Tomoaki Kanaya, Yoshio Tahara, Yasuhide Asaumi, Etsuko Tsuda, Michikazu Nakai, Kunihiro Nishimura, Toshihisa Anzai, Kengo Kusano, Hiroaki Shimokawa, Yoichi Goto, Satoshi Yasuda
OBJECTIVE: Coronary artery ectasia (CAE) is an infrequently observed vascular phenotype characterized by abnormal vessel dilatation and disturbed coronary flow, which potentially promote thrombogenicity and inflammatory reactions. However, whether or not CAE influences cardiovascular outcomes remains unknown. APPROACH AND RESULTS: We investigated major adverse cardiac events (MACE; defined as cardiac death and nonfatal myocardial infarction [MI]) in 1698 patients with acute MI...
December 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
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