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coronary artery ectasia

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https://www.readbyqxmd.com/read/29570178/predictors-of-intravenous-immunoglobulin-non-response-and-racial-disparities-in-kawasaki-disease
#1
Daniel E Clark, Kara J Denby, Laura M Kaufman, Mary-Margaret A Fill, Bhinnata Piya, Shanthi Krishnaswami, Christopher Fonnesbeck, Natasha Halasa
BACKGROUND: Kawasaki disease (KD) is the most common cause of acquired heart disease in American children. IVIG non-response is a known risk factor for cardiac sequelae. Previously reported risk factors for non-response include age, male sex, and laboratory abnormalities. We set out to identify additional risk factors for IVIG non-response in a racially diverse KD population. METHODS: We conducted a retrospective chart review at a referral center in the Southeastern United States of children meeting ICD-9 criteria for KD and being treated with IVIG...
March 19, 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29564347/aneurysmal-coronary-artery-disease-an-overview
#2
REVIEW
Mohamed S ElGuindy, Ahmed M ElGuindy
Aneurysmal coronary artery disease (ACAD) comprises both coronary artery aneurysms (CAA) and coronary artery ectasia (CAE). The reported prevalence of ACAD varies widely from 0.2 to 10%, with male predominance and a predilection for the right coronary artery (RCA). Atherosclerosis is the commonest cause of ACAD in adults, while Kawasaki disease is the commonest cause in children and adolescents, as well as in the Far East. Most patients are asymptomatic, but when symptoms do exist, they are usually related to myocardial ischemia...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29564344/cardiovascular-outcomes-following-kawasaki-disease-in-moscow-russia-a-single-center-experience
#3
Galina Lyskina, Olga Bockeria, Olga Shirinsky, Alena Torbyak, Anna Leontieva, Nina Gagarina, Anna Satyukova, Julia Kostina, Olga Vinogradova
Background: Awareness of Kawasaki disease (KD) is emerging in Russia but the diagnosis is still often missed. Methods: This is a retrospective study of 303 children with KD who received care at a single center in Moscow over the period from 2004 to 2016. Results: Overall, coronary artery aneurysms were documented in 91 (30,0%) of 303 patients and transient ectasia in 40 (13,2%). Intracoronary thrombi were found in 12 of 15 patients with giant aneurysms and in 3 patients with medium-sized aneurysms. Conclusion: The patients with KD in the Moscow region had typical features of the disease described in the literature but the proportion of patients with coronary artery aneurysms was higher than reported from other countries...
October 31, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29468725/a-clinical-risk-score-to-identify-patients-at-high-risk-of-very-late-stent-thrombosis
#4
Thea C Godschalk, Marieke E Gimbel, Wouter W Nolet, Dionne J van Kessel, Giovanni Amoroso, Willem J Dewilde, Joanna J Wykrzykowska, Paul W Janssen, Thomas O Bergmeijer, Johannes C Kelder, Ton Heestermans, Jurriën M Ten Berg
OBJECTIVES: The aim of this study was to determine predictors of very late stent thrombosis (VLST; >1 year after stenting), and to evaluate whether addition of these predictors to the dual antiplatelet therapy (DAPT) score would improve the ability to identify patients at high risk of VLST who might benefit from DAPT. BACKGROUND: VLST is a severe complication of percutaneous coronary intervention (PCI). Extended knowledge about the predictors of VLST is needed to prevent this life-threatening complication...
February 22, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29404853/implantation-of-multiple-polytetrafluoroethylene-covered-stent-inside-drug-eluting-stent-to-rescue-purulent-coronary-artery-ectasia-with-giant-saccular-aneurysm
#5
Yusuke Namba, Toshiaki Yamanaka, Jun Ida, Takefumi Oka
A 79-year-old male with diabetes mellitus and old cerebral infarction was admitted to hospital due to fever and palpitation. Diagnosis of purulent pericarditis was established by pericardial effusion examination. The patient's general condition improved temporarily after drainage of the pericardial effusion. However, computed tomography demonstrated a saccular aneurysm arising from RCA have rapidly grown even larger, up to 63 × 51 mm on 7th hospital day. This indicated that the risk of rupture of the aneurysm was high...
February 5, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29339675/association-of-serum-prolidase-activity-in-patients-with-isolated-coronary-artery-ectasia
#6
Erdal Aktürk, Lütfü Aşkın, Hüseyin Nacar, M Hakan Taşolar, Serdar Türkmen, Mustafa Çetin, Mehmet Bozkurt
OBJECTIVE: Coronary artery ectasia (CAE) is defined as an angiographic enlargement of a portion of the coronary artery between 1.5 and 2 times the diameter of the adjacent normal coronary artery. It has been demonstrated that increased serum prolidase activity (SPA) is associated with increased collagen turnover. We aimed to analyze the relationship between CAE and serum SPA levels. METHODS: This study used a prospective case protocol design. A total of 40 consecutive patients with isolated right CAE and normal coronary arteries (23 men, 17 women; mean age, 62...
January 17, 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29337902/cytokine-disturbances-in-coronary-artery-ectasia-do-not-support-atherosclerosis-pathogenesis
#7
Usama Boles, Anders Johansson, Urban Wiklund, Zain Sharif, Santhosh David, Siobhan McGrory, Michael Y Henein
BACKGROUND: Coronary artery ectasia (CAE) is a rare disorder commonly associated with additional features of atherosclerosis. In the present study, we aimed to examine the systemic immune-inflammatory response that might associate CAE. METHODS: Plasma samples were obtained from 16 patients with coronary artery ectasia (mean age 64.9 ± 7.3 years, 6 female), 69 patients with coronary artery disease (CAD) and angiographic evidence for atherosclerosis (age 64.5 ± 8...
January 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29317980/a-history-of-kawasaki-disease-from-childhood-and-coronary-artery-ectasia-with-recurrent-st-elevation-myocardial-infarction-a-therapeutic-challenge
#8
Ashraf Abugroun, Daniel Vilchez, Osama Hallak, Anahita Shahrrava
Coronary artery ectasia (CAE) is an uncommon anomaly, usually found in 1.2-2% of patients undergoing coronary angiography, defined as a segment of the coronary artery that has a diameter of more than 1.5 times the normal adjacent segments. Atherosclerosis is considered as the cause of half of the CAE cases. We herein present a 65-year-old Asian male with past medical history of Kawasaki disease (KD) who developed recurrent episodes of inferior wall ST-elevation myocardial infarction (STEMI) despite treatment with dual antiplatelet therapy (DAPT)...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29317970/evaluation-of-the-tp-te-interval-qtc-and-p-wave-dispersion-in-patients-with-coronary-artery-ectasia
#9
Ronan Conlon, Richard Tanner, Santhosh David, Gabor Szeplaki, Joseph Galvin, John Keaney, Edward Keelan, Usama Boles
Background: Coronary artery ectasia (CAE) is defined as a diffuse dilatation of the diameter of the ectatic segment of the coronary artery, 1.5 times greater than that of the adjacent segment. The Tp-Te interval, P-wave and QTc dispersions are relatively new electrocardiographic markers associated with an increased risk of developing arrhythmias. Despite CAE increasing in prevalence in recent years, there is a sparsity of data available about its arrhythmogenic effect. The aim of the study was to evaluate QTc, P-wave dispersion and Tp-Te and Tp-Te/QT ratio in patients with CAE...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29246775/coronary-ectasia-in-amyloid-cardiomyopathy-and-neuropathy-due-to-the-transthyretin-mutation-c-323a-g
#10
Josef Finsterer, Claudia Stöllberger, Helmut Rauschka, Edmund Gatterer
BACKGROUND: atrial fibrillation(AF) is a frequent manifestation of cardiac involvement in genetic and wild-type transthyretin-related familial amyloidosis(TTR-FA). However, ectasia of coronary arteries and ablation for AF have not been reported in TTR-FA. METHODS AND RESULTS: A 65yo male developed progressive sensori-motor polyneuropathy since age 59y. At age 60y bifascicular block and myocardial thickening were recognised. At age 62y heart failure developed and work-up with cardiac MRI suggested amyloidosis but biopsy was non-informative...
March 2018: Heart & Lung: the Journal of Critical Care
https://www.readbyqxmd.com/read/29181042/associations-between-coronary-artery-disease-aneurysm-and-ectasia
#11
Cengiz Ovalı, Baktash Morrad
Aim: Investigation the frequency and contribution of coronary artery aneurysm/ectasia in addition to their correlation with coronary artery disease (CAD). Material and methods: We retrospectively evaluated the coronary angiography records of 6500 adult consecutive patients, and 418 of them were met inclusion criteria and used in the present study. The CAD was defined as the presence of angiographic coronary stenosis of > 50% of the luminal diameter in no less than one of the epicardial coronary arteries...
September 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29115035/role-of-imaging-studies-in-kawasaki-disease
#12
Etsuko Tsuda, Manphool Singhal
Kawasaki disease is a medium vessel vasculitis which may be associated with coronary artery abnormalities. Recognition of these abnormalities depends upon various imaging modalities. While two-dimensional echocardiography remains the first line modality to identify coronary artery abnormalities, it is subject to several fallacies and is operator dependent. Computed tomography coronary angiography is rapidly emerging as a useful imaging modality for better characterization of dilatations, ectasia and aneurysms in the mid- and distal segments of coronary arteries...
January 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29106833/-coronary-ectasias-and-thrombosis
#13
M A Bouzid, H Benamer, X Halna du Fretay
Ectasias and coronary aneurysms are uncommon coronary artery diseases, can coexist and are poorly known. Their principal etiology in adults is coronary atherosclerosis. It has been suggested that these abnormalities would have poor prognosis and that slow flow could lead to in situ thrombosis and distal embolisation. However, ectasias and aneurysms are most often associated with coronary stenosis. We report a series of 47 cases of ectasias and coronary aneurysms with evaluation of the clinical and angiographic characteristics, the therapeutic choices and we review the literature concerning these lesions...
December 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29054186/isolated-coronary-artery-ectasia-clinical-angiographic-and-follow-up-characteristics
#14
Amit Malviya, Pravin K Jha, Animesh Mishra
BACKGROUND: Isolated Coronary artery ectasia (CAE) is considered an uncommon angiographic finding with varying patterns of presentation and carries significant morbidity burden to the patient. Our objective was to evaluate the prevalence of this condition, to analyse its clinical, angiographic, and follow up characteristics. PATIENTS AND METHODS: Coronary angiography was performed in 4950 patients from January 2009 to August 2014. The epidemiological, clinical, angiographic, and follow up characteristics of 52 patients with isolated CAE were examined...
September 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29051141/coronary-artery-ectasia-predicts-future-cardiac-events-in-patients-with-acute-myocardial-infarction
#15
Takahito Doi, Yu Kataoka, Teruo Noguchi, Tatsuhiro Shibata, Takahiro Nakashima, Shoji Kawakami, Kazuhiro Nakao, Masashi Fujino, Toshiyuki Nagai, Tomoaki Kanaya, Yoshio Tahara, Yasuhide Asaumi, Etsuko Tsuda, Michikazu Nakai, Kunihiro Nishimura, Toshihisa Anzai, Kengo Kusano, Hiroaki Shimokawa, Yoichi Goto, Satoshi Yasuda
OBJECTIVE: Coronary artery ectasia (CAE) is an infrequently observed vascular phenotype characterized by abnormal vessel dilatation and disturbed coronary flow, which potentially promote thrombogenicity and inflammatory reactions. However, whether or not CAE influences cardiovascular outcomes remains unknown. APPROACH AND RESULTS: We investigated major adverse cardiac events (MACE; defined as cardiac death and nonfatal myocardial infarction [MI]) in 1698 patients with acute MI...
December 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29046758/coronary-artery-ectasia-presenting-with-acute-inferior-wall-myocardial-infarction-in-a-young-adult
#16
Htun Latt, Sammy Aung, Kyaw Kyaw, Richard Seher
Coronary artery ectasia (CAE), a variant of coronary artery anomalies, is a rare clinical entity. Although atherosclerotic coronary artery disease (CAD) is the most common cause of acute coronary syndrome (ACS), CAE also conveys a relatively high risk for potentially life-threatening cardiac events. We report a case of a 35-year-old male with two-vessel CAE, who presented with acute inferior wall ST election myocardial infarction (STEMI). After initiating medical therapy including bivalirudin, emergent percutaneous coronary intervention (PCI) with stenting of postero-lateral branch of right coronary artery (RCA) was performed...
October 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29043397/myocardial-fistulisation-and-coronary-arterial-ectasia-in-children-with-univentricular-circulation-an-under-recognised-problem
#17
Daragh Finn, Kevin Walsh, David Roberson, Colin J McMahon
Among 241 children with univentricular circulation who underwent total cavopulmonary connection (Glenn or Fontan) over a 17 years period (January 2000-April 2017), we found two patients who had diffuse coronary fistulisation of their myocardium (0.8%). We also report an additional third case from Oak Lawn, Illinois, USA. One of the children had documented normal coronary arteries and myocardium at catheterisation prior to development of the fistulisation process. The same child also developed extensive veno-venous collaterals...
October 17, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29038408/-aortitis-syndrome-requiring-redo-bentall-procedure-with-coronary-artery-bypass-grafting-due-to-graft-detachment-report-of-a-case
#18
Masami Sotokawa, Hideyuki Tomioka, Takashi Azuma, Shigeyuki Aomi, Kenji Yamazaki
A 53-year-old woman was referred to us for reoperation of aortic root. Twenty-three years ago, she was diagnosed with aortitis and suffered from annuloaortic ectasia, aortic regurgitation, severe stenosis of left carotid and subclavian arteries and occulusion of the main trunk of left coronary artery. The left coronary system was perfused by collateral arteries from right coronary artery. She had undergone original Bentall procedure( Cooley graft 26 mm+SJM valve 25 mm) with coronary artery bypass grafting (CABG)[saphenous vein graft (SVG)-left anterior descending artery (LAD)]...
October 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28974667/intracoronary-administration-of-thrombolysis-for-severe-coronary-artery-ectasia-presenting-as-an-acute-inferior-st-segment-elevation-myocardial-infarction
#19
Avadhesh Saraswat, Atifur Rahman, Ravinder Batra
We present a 75-year-old male with acute inferior ST-elevation myocardial infarction, severe coronary artery ectasia, and large thrombus burden in the right coronary artery to support the use of intracoronary thrombolysis as a second-line therapy for a large thrombus burden in primary percutaneous coronary intervention.
October 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/28884991/acute-cardiac-disease-in-a-patient-with-hyper-ige-syndrome
#20
A Castilano, H Watti, A Abdulbaki, K Modi, J A Bocchini, S L Bahna
We describe the case of a 24-year-old male with hyper-IgE syndrome (HIES) which was diagnosed at 4 years of age and died from a very rare cardiac complication. He had typical clinical and laboratory manifestations of HIES, including total serum IgE as high as > 100,000 IU/mL. Stem cell transplantation was not available. During the 20-year follow-up, he suffered numerous various infections of the skin and deep organs, partial lung resection, as well as multiple bone fractures. At age 24, he developed acute decompensated heart failure associated with elevated serum troponin I and brain natriuretic protein...
September 2017: European Annals of Allergy and Clinical Immunology
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