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Multinodular goiter

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https://www.readbyqxmd.com/read/28078873/fine-needle-aspiration-cytology-of-650-thyroid-nodules-operated-for-multinodular-goiter-a-cyto-histological-correlation-based-on-the-new-italian-cytological-classification-siapec-2014
#1
F Tartaglia, A Giuliani, L Tromba, S Carbotta, M Karpathiotakis, G Tortorelli, F Pelle, R Merola, C Donello, G Carbotta, L De Anna, G Conzo, S Sorrenti, S Ulisse
The new Italian cytological classification (SIAPEC 2014) of thyroid nodules, in line with those of Bethesda and BTA-RCPath, replaces the previous TIR3 class with two new classes (TIR3A and TIR3B), which correspond to different risks of malignancy and clinical actions required. The present study was conducted to evaluate the diagnostic accuracy of the new SIAPEC classification as opposed to its previous version (SIAPEC 2007). Preoperative cytology was compared with the final histology obtained from 650 consecutive patients who underwent total thyroidectomy for multinodular goiter...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28039060/prophylactic-oral-calcium-supplementation-therapy-to-prevent-early-post-thyroidectomy-hypocalcemia-and-evaluation-of-postoperative-parathyroid-hormone-levels-to-detect-hypocalcemia-a-prospective-randomized-study
#2
Ilker Murat Arer, Murat Kus, Nezih Akkapulu, Huseyin Ozgur Aytac, Hakan Yabanoglu, Kenan Caliskan, Mehmet Akin Tarim
BACKGROUND: Postoperative hypocalcemia is the most common complication after total thyroidectomy. Postoperative parathyroid hormone (PTH) measurement is one of the methods to detect or prevent postoperative hypocalcemia. Prophylactic oral calcium supplementation is another method to prevent early postoperative hypocalcemia. The aim of this study is to detect the accurate timing of PTH and evaluate efficacy of routine oral calcium supplementation for postoperative hypocalcemia. METHODS: A total of 106 patients were performed total thyroidectomy...
December 27, 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/28031674/takotsubo-cardiomyopathy-associated-with-primary-hyperthyroidism-secondary-to-toxic-multinodular-goiter
#3
Dale Murdoch, William O'Callaghan, Elham Reda, Selvanayagam Niranjan
Takotsubo cardiomyopathy is increasingly recognized as a distinct clinical entity. An association with thyroid disease has been identified in several case reports, mostly in the context of Grave disease. We report the case of a 67-year-old woman presenting with takotsubo cardiomyopathy and thyrotoxicosis secondary to toxic multinodular goiter. Previously unreported, this suggests that this association is related to the direct effects of thyroid hormone, rather than an autoimmune mechanism. Thyroid disease should be considered in patients presenting with takotsubo cardiomyopathy...
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28025831/new-daily-persistent-headache-caused-by-a-multinodular-goiter-and-headaches-associated-with-thyroid-disease
#4
Randolph W Evans, Josefine S Timm
A 33-year-old female is presented with the first case to our knowledge of new daily persistent headache (NDPH) with a large right benign non-toxic multinodular goiter causing carotid and vertebral compression with complete resolution of the headache immediately after thyroidectomy. Although this may be quite rare, hypothyroidism or hyperthyroidism causing NDPH, migraine, or an exacerbation of pre-existing migraine is not. Clinicians should consider routinely obtaining serum thyroid-stimulating hormone (TSH) and free T4 in patients with new onset frequent headaches or an exacerbation of prior primary headaches...
December 27, 2016: Headache
https://www.readbyqxmd.com/read/28005977/should-the-prevalence-of-incidental-thyroid-cancer-determine-the-extent-of-surgery-in-multinodular-goiter
#5
Krzysztof Kaliszewski, Marta Strutyńska-Karpińska, Agnieszka Zubkiewicz-Kucharska, Beata Wojtczak, Paweł Domosławski, Waldemar Balcerzak, Tadeusz Łukieńczuk, Zdzisław Forkasiewicz
BACKGROUND: The most appropriate surgical procedure for multinodular goiter (MNG) remains under debate. Incidental thyroid carcinoma (ITC) is often identified on histopathological examination after thyroidectomy performed for presumed benign MNG. AIM OF THE STUDY: The aim of the study was to determine the value of radical surgery for MNG patients considering the prevalence of ITC diagnosed postoperatively. MATERIALS AND METHODS: We conducted retrospective analysis of the medical records of 2,306 patients surgically treated for MNG between 2008 and 2013 at one center...
2016: PloS One
https://www.readbyqxmd.com/read/27988915/airway-obstruction-caused-by-substernal-thyrotoxic-multinodular-goiter
#6
Haruihiro Sato, Ryota Masuda, Masayuki Iwazaki, Chie Inomoto, Sunao Shoji, Yoshiyuki Robert Osamura
BACKGROUND: Substernal thyrotoxic multinodular goiter (MNG) shows signs and symptoms as a result of compression of adjacent organs and thyrotoxicosis. However, acute airway obstruction is rarely caused by substernal thyrotoxic MNG. CASE REPORT: We have described a 56-year-old Japanese woman who demonstrated acute airway obstruction because of compression of the airway by substernal thyrotoxic MNG. She had been diagnosed with substernal thyrotoxic MNG 6 years back...
December 20, 2016: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/27933384/thyroid-autoimmunity-is-really-associated-with-papillary-thyroid-carcinoma
#7
Alev Selek, Berrin Cetinarslan, Ilhan Tarkun, Zeynep Canturk, Berna Ustuner, Zeynep Akyay
The incidence of thyroid cancer has been greatly increasing. Several studies aimed to investigate biomarkers for prediction of thyroid cancer. Some of these studies have suggested that thyroid autoantibodies (TAb) could be used as predictors of thyroid cancer risk, but the correlation between TAb and PTC is still a matter of debate. The aim of this study is to evaluate thyroid autoimmunity and TAbs in patients with PTC and benign multinodular goiter (MNG) to investigate if TAbs and autoimmune thyroid disease (ATD) could predict thyroid malignancy...
December 8, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27899986/metastasis-of-renal-cell-carcinoma-to-the-parathyroid-gland-16-years-after-radical-nephrectomy-a-case-report
#8
Liborio Torregrossa, Maria Isabella Rotondo, Andrea Cacciato Insilla, David Galleri, Federica Guidoccio, Paolo Miccoli, Virginia A Livolsi, Fulvio Basolo
Renal cell carcinoma (RCC) has a high metastatic potential, and most commonly metastasizes via the bloodstream, although lymphatic metastases also occur. RCC is well-known for its propensity to metastasize to unusual sites, and late metastasis, even after a number of years, is common. The occurrence of RCC metastasis to the head and neck region is uncommon, and occurs primarily in the thyroid gland and in patients with widespread dissemination. Involvement of the parathyroid gland in metastatic carcinoma is extremely rare...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27872536/phrenic-nerve-palsy-as-initial-presentation-of-large-retrosternal-goitre
#9
Arsheed Hussain Hakeem, Imtiyaz Hussain Hakeem, Fozia Jeelani Wani
Unilateral phrenic nerve palsy as initial presentation of the retrosternal goitre is extremely rare event. This is a case report of a 57-year-old woman with history of cough and breathlessness of 3 months duration, unaware of the thyroid mass. She had large cervico-mediastinal goiter and chest radiograph revealed raised left sided hemidiaphragm. Chest CT scan did not reveal any lung parenchymal or mediastinal pathology. The patient underwent a total thyroidectomy through a cervical approach. The final pathology was in favor of multinodular goitre...
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27784321/horner-s-syndrome-an-unusual-complication-of-thyroidectomy-a-case-report
#10
Sanjeewa A Seneviratne, Dewamuni S Kumara, Akram M P Drahaman
BACKGROUND: Horner's syndrome is a very rare complication following surgery of the thyroid gland with only a handful of cases reported in the literature. Exact pathophysiology of post-thyroidectomy Horner's syndrome is not fully understood, and once diagnosed, management remains mostly conservative. CASE PRESENTATION: A 36-year-old Sri Lankan Sinhalese woman developed unilateral partial ptosis with enophthalmos and myosis one week after total thyroidectomy for a benign multinodular goiter...
October 26, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27779196/thyroid-dysfunction-in-primary-biliary-cholangitis-a-comparative-study-at-two-european-centers
#11
Annarosa Floreani, Chiara Mangini, Anna Reig, Irene Franceschet, Nora Cazzagon, Lisa Perini, Llorenç Caballería, Silvia Cocchio, Vincenzo Baldo, Albert Parés
OBJECTIVES: Primary biliary cholangitis (PBC) is often associated with other autoimmune diseases, but little is known about the influence of thyroid disease (TD) on the natural history of PBC. Our aim is to analyze the association between PBC and TD, and the latter's impact on the natural history of PBC at two European centers. METHODS: The study involved 921 PBC patients enrolled between 1975 and 2015 in Padova (376 patients) and Barcelona (545 patients), with a mean follow-up of 126...
January 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27774323/syndrome-of-reduced-sensitivity-to-thyroid-hormones-two-case-reports-and-a-literature-review
#12
Anastasios Anyfantakis, Dimitrios Anyfantakis, Irene Vourliotaki
Resistance to thyroid hormone (RTH) is an extremely rare dominantly inherited condition of impaired tissue responsiveness to thyroid hormone (TH). Most patients with RTH have mutations in the gene that encodes the β isoform of the receptor of thyroid hormone (THR-β gene). Mutant receptors are unable to activate or repress target genes. The majority of them are asymptomatic or rarely have hypo- or hyperthyroidism. RTH is suspected by the finding of persistent elevation of serum levels of free T3 (FT3) and free T4 (FT4) and nonsuppressed TSH...
2016: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/27773627/-what-would-you-do-in-front-of-a-patient-with-a-horner-syndrome
#13
A Camós-Carreras, S Fontana, S Ortiz-Pérez
Horner's syndrome (HS) occurs when there is disruption to the oculosympathetic pathway. Its features include eyelid ptosis, miosis and anhidrosis. The aetiology of this syndrome is varied and includes tumours, trauma, vascular disease and iatrogenic. Different pharmacologic tests are used for diagnosis, such as cocaine, hydroxyamphetamine and apraclonidine; while neuroimaging helps elucidating the aetiology. We present a case of a 63-year-old female referred to our service with a 4-month history of right eyelid ptosis...
October 20, 2016: Semergen
https://www.readbyqxmd.com/read/27772959/multinodular-goiter-with-adipose-metaplasia-a-case-report
#14
Worapop Suthiwartnarueput
No abstract text is available yet for this article.
February 2016: Pathology
https://www.readbyqxmd.com/read/27716078/a-case-of-asystole-from-carotid-sinus-hypersensitivity-during-patient-positioning-for-thyroidectomy
#15
Emmanuel Lilitsis, Alexia Papaioannou, Aikaterini Hatzimichali, Konstantinos Spyridakis, Sofia Xenaki, George Chalkiadakis, Emmanuel Chrysos
BACKGROUND: We present a case of a patient with multinodular goiter disease who suffered asystole during head hyperextension for surgical positioning on the operational table. CASE PRESENTATION: Manipulation of carotid sinus may trigger bradycardia or even asystole even in patients without prior history of carotid sinus hypersensitivity. The time proximity between patient positioning and asystole, the late responsiveness to atropine, the immediate increase of heart rate after head elevation and the lack of any other trigger factor or prior history support the hypothesis of carotid sinus syndrome...
October 6, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/27703446/a-novel-germline-mutation-of-keap1-r483h-associated-with-a-non-toxic-multinodular-goiter
#16
Eijun Nishihara, Akira Hishinuma, Takahiko Kogai, Nami Takada, Mitsuyoshi Hirokawa, Shuji Fukata, Mitsuru Ito, Tomonori Yabuta, Mitsushige Nishikawa, Hirotoshi Nakamura, Nobuyuki Amino, Akira Miyauchi
BACKGROUND: A germline mutation of KEAP1 gene was reported as a novel genetic abnormality associated with familial multinodular goiter. That report was limited, and the pathogenic features were not well established. PATIENT FINDINGS: We report a 47-year-old Japanese woman who presented with hyperthyroidism and a large multinodular goiter. The family history was notable for a paternal history of goiter. Graves' disease was diagnosed based on positive TRAb, but scintiscan imaging showed that the patient's radioiodine uptake was restricted in the non-nodular areas, indicating largely cold nodules...
2016: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/27687679/anatomical-approach-to-surgery-for-intrathoracic-goiter
#17
Michael Vaiman, Inessa Bekerman
The anatomical approach to the intrathoracic goiter (ITG) was used to understand its etiology and to rationalize surgical technique of thyroidectomy. For a retrospective chart review, we selected cases of multinodular goiter with totally ITGs (n = 69; M 29, F 40), while 916 cases with cervical goiter were used for comparison. The topography of the thyroid gland was assessed against the tracheal rings and against the vertebrae. The regional anatomy of the thoracic inlet was assessed by its bony margins and the relations of structures traversing the area...
September 29, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27672642/incidentally-detected-hydatid-cyst-of-the-adrenal-gland-a-case-report
#18
Sami Akbulut
Hydatid cysts are a zoonotic disease that can involve many organs and tissues in the human body but primarily involve the liver and lungs. Of the main organs, adrenal glands are those seldom affected by hydatid cysts. The purpose of this study was to present a case with an incidentally detected hydatid cyst of the right adrenal gland on computed tomography, and a positive echincoccus IgG enzyme-linked immunosorbent assay test on top of a toxic multinodular thyroid goiter for which thyroidectomy was indicated...
September 16, 2016: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/27651822/stromal-tissue-as-an-adjunct-tool-in-the-diagnosis-of-follicular-thyroid-lesions-by-fine-needle-aspiration-biopsy
#19
Kien T Mai, Kevin Hogan
BACKGROUND: The stroma in fine-needle aspiration biopsy (FNAB) of thyroid lesions has not been well investigated. DESIGN: We studied 256 consecutive cases of thyroid FNAB prepared with traditional smear technique. The stroma was categorized: Type 1a consisted of long (more than 3 mm), broad bands composed of mesh containing collagen fibrils thickened by entrapped blood components and follicular cells. Type 1b consisted of dense strands/bands. Type 2 was similar to Type 1a but with shorter (<2 mm) and looser stromal strands...
2016: CytoJournal
https://www.readbyqxmd.com/read/27651121/total-thyroidectomy-a-clue-to-understanding-the-metabolic-changes-induced-by-subclinical-hyperthyroidism
#20
Pierre Bel Lassen, Aglaia Kyrilli, Maria Lytrivi, Maria Ruiz Patino, Bernard Corvilain
OBJECTIVE: The effects of endogenous subclinical hyperthyroidism (eSCH) on heart and bone have been well documented. There are only limited data available regarding the impact of eSCH on weight regulation and lipid metabolism. Our aim was to evaluate the changes in body weight and metabolic parameters after total thyroidectomy in patients with pre-operative eSCH compared with pre-operative patients with euthyroid (EUT). DESIGN: A retrospective study of 505 patients who underwent total thyroidectomy for benign multinodular goitre in an academic hospital in Brussels (Belgium) was performed...
September 21, 2016: Clinical Endocrinology
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