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https://www.readbyqxmd.com/read/29747489/different-patterns-of-risk-reducing-decisions-in-affected-or-unaffected-brca-pathogenic-variant-carriers
#1
Eun-Gyeong Lee, Hyok Jo Kang, Myong Cheol Lim, Boyoung Park, Soo Jin Park, So-Youn Jung, Seeyoun Lee, Han-Sung Kang, Sang-Yoon Park, Boram Park, Jungnam Joo, Jai Hong Han, Sun-Young Kong, Eun Sook Lee
Purpose: The purpose of this study was to investigate decision patterns to reduce the risks of BRCA-related breast and gynecologic cancers in carriers of BRCA pathogenic variants. We found a change in risk-reducing (RR) management patterns after December 2012, when the National Health Insurance System (NHIS) of Korea began to pay for BRCA testing and risk-reducing salpingo-oophorectomy (RRSO) in pathogenic-variant carriers. Materials and Methods: The study group consisted of 992 patients, including 705 with breast cancer (BC), 23 with ovarian cancer (OC), 10 with both, and 254 relatives of high-risk patients who underwent BRCA testing at the National Cancer Center of Korea from January 2008 to December 2016...
May 4, 2018: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/29734759/trends-in-the-prevalences-of-selected-birth-defects-in-korea-2008%C3%A2-2014
#2
Jung-Keun Ko, Dirga Kumar Lamichhane, Hwan-Cheol Kim, Jong-Han Leem
Little information is available on the prevalences of birth defects in Korea. The aims of this study were to estimate recent prevalences of selected birth defects and to analyze the prevalence trends of these defects during the period from 2008 to 2014. Prevalences were calculated for 69 major birth defects using health insurance claim data obtained from the Korea National Health Insurance Service (NHIS). Prevalence rate ratios were calculated using Poisson regression to analyze trends over the 7-year study period...
May 5, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29718833/comorbid-risks-of-psychological-disorders-and-gastroesophageal-reflux-disorder-using-the-national-health-insurance-service-national-sample-cohort-a-strobe-compliant-article
#3
Ye-Seul Lee, Bo-Hyoung Jang, Seong-Gyu Ko, Younbyoung Chae
This study was performed to examine the comorbidity risks between psychological disorders, such as depression, and gastroesophageal reflux disease (GERD) using nationally representative data from a National Sample Cohort of the National Health Insurance Service in Korea.The National Health Insurance Service-National Sample Cohort (NHIS-NSC) database from 2010 to 2012 was used in this study. GERD patients were defined as those diagnosed with specific tests, with screened medication, and without any other gastrointestinal diseases...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29696814/difference-in-prostate-cancer-incidence-around-sixty-years-effects-of-age-and-metabolic-diseases
#4
Jin Bong Choi, Jung Ho Kim, Sung-Hoo Hong, Kyung-Do Han, U-Syn Ha
We examined the risk of prostate cancer in the Korean population stratified on the basis of age group and risk based on metabolic diseases, using National Health Insurance System (NHIS) data. Of the 51,827,813 people from the NHIS data in 2015, 10,879,591 men without prostate cancer who underwent a health examination were analyzed. The risk of prostate cancer was analyzed with stratification by age. Multivariate-adjusted Cox regression analysis was conducted to examine the association between prostate cancer and metabolic diseases by age groups...
April 25, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29676539/past-and-current-status-of-adult-type-2-diabetes-mellitus-management-in-korea-a-national-health-insurance-service-database-analysis
#5
REVIEW
Seung Hyun Ko, Kyungdo Han, Yong Ho Lee, Junghyun Noh, Cheol Young Park, Dae Jung Kim, Chang Hee Jung, Ki Up Lee, Kyung Soo Ko
Korea's National Healthcare Program, the National Health Insurance Service (NHIS), a government-affiliated agency under the Korean Ministry of Health and Welfare, covers the entire Korean population. The NHIS supervises all medical services in Korea and establishes a systematic National Health Information database (DB). A health information DB system including all of the claims, medications, death information, and health check-ups, both in the general population and in patients with various diseases, is not common worldwide...
April 2018: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29666179/increasing-trends-in-hospital-care-burden-of-atrial-fibrillation-in-korea-2006-through-2015
#6
Daehoon Kim, Pil-Sung Yang, Eunsun Jang, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Jong Youn Kim, Hui-Nam Pak, Moon-Hyoung Lee, Boyoung Joung, Gregory Y H Lip
OBJECTIVE: Temporal changes in the healthcare burden of atrial fibrillation (AF) are less well known in rapidly ageing Asian countries. We examined trends in hospitalisations, costs, treatment patterns and outcomes related to AF in Korea. METHODS: Using the National Health Insurance Service (NHIS) database involving the entire adult Korean population (n=41 701 269 in 2015), we analysed a nationwide AF cohort representing 931 138 patients with AF. We studied all hospitalisations due to AF from 2006 to 2015...
April 17, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29614498/development-of-an-algorithm-for-stroke-prediction-a-national-health-insurance-database-study-in-korea
#7
Seung Nam Min, Se Jin Park, Dong Joon Kim, Murali Subramaniyam, Kyung-Sun Lee
BACKGROUND: Stroke is the second leading cause of death worldwide and remains an important health burden both for the individuals and for the national healthcare systems. Potentially modifiable risk factors for stroke include hypertension, cardiac disease, diabetes, and dysregulation of glucose metabolism, atrial fibrillation, and lifestyle factors. OBJECTS: We aimed to derive a model equation for developing a stroke pre-diagnosis algorithm with the potentially modifiable risk factors...
April 3, 2018: European Neurology
https://www.readbyqxmd.com/read/29554108/the-economic-burden-of-rotavirus-infection-in-south-korea-from-2009-to-2012
#8
Kyung Suk Lee, Ye-Rin Lee, So-Youn Park, In-Hwan Oh
Rotavirus is a common cause of diarrhea worldwide, and vaccination prevents rotaviral gastroenteritis. Since the rotavirus vaccine was introduced in Korea in 2007, the prevalence of rotaviral gastroenteritis has decreased. However, little is known on the economic burden of rotavirus infection and its variations in Korea. Here, we estimated the economic costs of rotavirus infection from 2009 to 2012 using nationwide data from the National Health Insurance Service (NHIS) claims. Socioeconomic costs were subdivided into direct and indirect and measured with a prevalence-based approach...
2018: PloS One
https://www.readbyqxmd.com/read/29497986/liver-cirrhosis-and-cancer-comparison-of-mortality
#9
Wankyo Chung, Changik Jo, Woo Jin Chung, Dong Joon Kim
BACKGROUND: Liver cirrhosis is known to have low survival rate, and its assessment in relation with other fatal diseases will help us design appropriate health interventions. This study compares the mortality of liver cirrhosis with that of five major cancers (lung, colorectal, stomach, liver, and breast cancers). METHODS AND RESULTS: We used the National Health Insurance Service-National Sample Cohort (NHIS-NSC) which provides data for 1,025,340 representative samples of the 46,605,433 people in Korea from 2002 to 2010...
March 1, 2018: Hepatology International
https://www.readbyqxmd.com/read/29486402/clinical-epidemiology-of-long-term-suicide-risk-in-a-nationwide-population-based-cohort-study-in-south-korea
#10
Hyewon Lee, Woojae Myung, Chunsoo Lee, Junbae Choi, Ho Kim, Bernard J Carroll, Doh Kwan Kim
We investigated the effects of a large range of clinical factors on the long-term risk of suicide in the general population of South Korea. We analyzed the National Health Insurance Service-National Sample Cohort (NHIS-NSC) database in South Korea. A total of 300,232 individuals were followed for up to 12 years. We obtained information on demographic variables (age and sex), lifestyle variables (cigarette smoking, alcohol drinking and exercise), psychiatric and physical disorders, laboratory examination results and physical examination findings...
May 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29445630/effects-of-first-diagnosed-diabetes-mellitus-on-medical-visits-and-medication-adherence-in-korea
#11
Kim Hyeongsu, Shin Soon-Ae, Lee Kunsei, Park Jong-Heon, Han Tae Hwa, Park Minsu, Minsu Eunyoung, Jeong Hyoseon, Lee Jung-Hyun, Ahn Hyemi, Kim Vitna
Background: The National Health Insurance Service (NHIS) conducted a screening test to detect chronic diseases such as hypertension and diabetes in Korea. This study evaluated the effects of health screening for DM on pharmacological treatment. Methods: The data from qualification and the General Health Screening in 2012, the insurance claims of medical institutions from Jan 2009 to Dec 2014, and the diabetic case management program extracted from the NHIS administrative system were used...
February 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29408160/ten-year-prediction-of-suicide-death-using-cox-regression-and-machine-learning-in-a-nationwide-retrospective-cohort-study-in-south-korea
#12
Soo Beom Choi, Wanhyung Lee, Jin-Ha Yoon, Jong-Uk Won, Deok Won Kim
BACKGROUND: Death by suicide is a preventable public health concern worldwide. The aim of this study is to investigate the probability of suicide death using baseline characteristics and simple medical facility visit history data using Cox regression, support vector machines (SVMs), and deep neural networks (DNNs). METHOD: This study included 819,951 subjects in the National Health Insurance Service (NHIS)-Cohort Sample Database from 2004 to 2013. The dataset was divided randomly into two independent training and validation groups...
April 15, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29397642/identifying-adverse-events-using-international-classification-of-diseases-tenth-revision-y-codes-in-korea-a-cross-sectional-study
#13
Minsu Ock, Hwa Jung Kim, Bomin Jeon, Ye-Jee Kim, Hyun Mi Ryu, Moo-Song Lee
Objectives: The use of administrative data is an affordable alternative to conducting a difficult large-scale medical-record review to estimate the scale of adverse events. We identified adverse events from 2002 to 2013 on the national level in Korea, using International Classification of Diseases, tenth revision (ICD-10) Y codes. Methods: We used data from the National Health Insurance Service-National Sample Cohort (NHIS-NSC). We relied on medical treatment databases to extract information on ICD-10 Y codes from each participant in the NHIS-NSC...
January 2018: Journal of Preventive Medicine and Public Health, Yebang Ŭihakhoe Chi
https://www.readbyqxmd.com/read/29372929/gamma-glutamyl-transferase-predicts-future-stroke-a-korean-nationwide-study
#14
Wookjin Yang, Chi Kyung Kim, Do Yeon Kim, Han-Gil Jeong, Seung-Hoon Lee
OBJECTIVE: Although gamma-glutamyl transferase (GGT) is generally regarded as an alternative biomarker for alcohol consumption, its independent role in vascular diseases emerged recently. However, its role in stroke remains unknown. The aim of this study is to clarify the impact of GGT on stroke in a large-sized, national, standardized population cohort in Korea. METHODS: In Korea, the National Health Insurance Service (NHIS) provides full-coverage health insurance service for all citizens...
February 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29353222/cohort-study-of-cervical-ossification-of-posterior-longitudinal-ligament-in-a-korean-populations-demographics-of-prevalence-surgical-treatment-and-disability
#15
Jaeyong Shin, Yong Wook Kim, Sang Gyu Lee, Eun-Cheol Park, Seo Yeon Yoon
OBJECTIVE: To investigate the demographic characteristics of cervical ossification of posterior longitudinal ligament (OPLL) including prevalence, surgical treatment, and disability in Korean population using Korean National Health Insurance Service National Sample Cohort (NHIS-NSC) data, and to analyze association between accessibility for surgical treatment and socioeconomic factors. PATIENTS AND METHODS: A population-based cohort study was conducted using stratified representative sampling from NHIS-NSC data from the year 2002 to 2013...
March 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29319496/geographic-variations-in-antibiotic-prescription-for-pediatric-acute-upper-respiratory-tract-infections-in-south-korea
#16
Youn Jung, Hyemin Cho, Eunhee Ji, Eun-Ji Park, Sunmee Jang
OBJECTIVE: This study aimed to investigate the factors affecting the geographic differences in antibiotic prescription rates in pediatric upper respiratory tract infections (URI) patients in South Korea. MATERIALS AND METHODS: We performed a nationwide cross-sectional study using 228 administrative districts of Korea, which are the unit of analysis. Prescription rate of antibiotics, the outcome variable, was measured as the proportion of antibiotic prescription days out of total visit days for the treatment of acute URIs using National Health Insurance Service (NHIS) claims data for 2012...
April 2018: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29215822/eleven-year-cumulative-incidence-and-estimated-lifetime-prevalence-of-urolithiasis-in-korea-a-national-health-insurance-service-national-sample-cohort-based-study
#17
Bum Sik Tae, Ulanbek Balpukov, Sung Yong Cho, Chang Wook Jeong
BACKGROUND: The purpose of this study was estimation of the cumulative incidence and lifetime prevalence of urolithiasis in Korea. METHODS: We used a National Health Insurance Service (NHIS) sample cohort dataset that included approximately 1 million individuals from Korea. Data from January 2002 to December 2013 were collected. We calculated the annual prevalence, recurrence rate, and estimate lifetime prevalence of urolithiasis. Multivariate logistic regression analysis was used to identify risk factors associated with urolithiasis...
January 8, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29212527/anemia-is-associated-with-incidence-of-dementia-a-national-health-screening-study-in-korea-involving-37-900-persons
#18
Su-Min Jeong, Dong Wook Shin, Ji Eun Lee, Jung Hyeon Hyeon, Jinkook Lee, SangYun Kim
BACKGROUND: The aim of this study was to investigate whether anemia is associated with dementia incidence in the elderly. METHODS: Using the Korean National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) database, we identified 66-year-old subjects (n = 37,900) who were free of dementia and stroke. Anemia (hemoglobin < 12 g/dl for women and < 13 g/dl for men) and the severity of anemia (mild, moderate, or severe) were defined using World Health Organization criteria...
December 6, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/29081218/effects-of-aspirin-nonsteroidal-anti-inflammatory-drugs-statin-and-cox2-inhibitor-on-the-developments-of-urological-malignancies-a-population-based-study-with-10-year-follow-up-data-in-korea
#19
Minyong Kang, Ja Hyeon Ku, Cheol Kwak, Hyeon Hoe Kim, Chang Wook Jeong
Purpose: The purpose of this study was to determine the impact of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), statin and cyclooxygenase 2 (COX-2) inhibitor on the development of kidney, prostate and urothelial cancers by analyzing the Korean National Health Insurance Service-National Sample Cohort (NHIS-NSC) database. Materials and Methods: Among a representative sample cohort of 1,025,340 participants in NHIS-NSC database in 2002, we extracted data of 799,850 individuals who visited the hospital more than once, and finally included 321,122 individuals aged 40 and older...
October 27, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/29065115/seroprevalence-and-disease-burden-of-acute-hepatitis-a-in-adult-population-in-south-korea
#20
Jin Gu Yoon, Min Joo Choi, Jae Won Yoon, Ji Yun Noh, Joon Young Song, Hee Jin Cheong, Woo Joo Kim
BACKGROUND: Adult seroprevalence of HAV is decreasing in developed countries including South Korea, due to general sanitation improvement. Although hepatitis A vaccination was introduced in South Korea more than 20 years ago, recent infection rates have not decreased. In this study, we investigate the seroprevalence of anti-HAV IgG, and estimate the national disease burden of acute hepatitis A in adult population. METHODS: Seroprevalence data were collected from health promotion center of Korea University Guro Hospital, in Seoul, Korea from 2010 to 2014...
2017: PloS One
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