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https://www.readbyqxmd.com/read/28211806/digital-breast-tomosynthesis-plus-mammography-magnetic-resonance-imaging-plus-mammography-and-mammography-alone-a-comparison-of-diagnostic-performance-in-symptomatic-women
#1
Wei Tang, Fei-Xiang Hu, Hui Zhu, Qi-Feng Wang, Ya-Jia Gu, Wei-Jun Peng
PURPOSE: To compare the diagnostic efficiency of digital breast tomosynthesis (DBT) plus digital mammography (DM) and magnetic resonance imaging (MRI) plus DM in symptomatic women. MATERIALS AND METHODS: The protocol used in our study was accepted by the ethics committee at our hospital, and informed consent was obtained from all patients. Between June and December 2014, 197 patients with 238 histologically proven lesions all underwent DM, DBT and MRI. Two radiologists were responsible for interpreting all images according to the Breast Imaging Reporting and Data System (BI-RADS)...
February 17, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28199152/can-radiologists-predict-the-presence-of-ductal-carcinoma-in-situ-and-invasive-breast-cancer
#2
Shadi Aminololama-Shakeri, Chris I Flowers, Christine E McLaren, Dorota J Wisner, Jade de Guzman, Joan E Campbell, Lawrence W Bassett, Haydee Ojeda-Fournier, Karen Gerlach, Jonathan Hargreaves, Sarah L Elson, Hanna Retallack, Bonnie N Joe, Stephen A Feig, Colin J Wells
OBJECTIVE: We hypothesize that radiologists' estimated percentage likelihood assessments for the presence of ductal carcinoma in situ (DCIS) and invasive cancer may predict histologic outcomes. MATERIALS AND METHODS: Two hundred fifty cases categorized as BI-RADS category 4 or 5 at four University of California Medical Centers were retrospectively reviewed by 10 academic radiologists with a range of 1-39 years in practice. Readers assigned BI-RADS category (1, 2, 3, 4a, 4b, 4c, or 5), estimated percentage likelihood of DCIS or invasive cancer (0-100%), and confidence rating (1 = low, 5 = high) after reviewing screening and diagnostic mammograms and ultrasound images...
February 15, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28182285/an-audit-of-the-results-of-ultrasound-guided-core-needle-biopsy-of-mammography-versus-ultrasound-screen-detected-breast-lesions
#3
Sun Jung Rhee, Boo-Kyung Han, Eun Sook Ko, Ji Soo Choi, Eun Young Ko
PURPOSE: To analyze the malignancy rate of ultrasound-guided core needle biopsy (US-CNB) for screen-detected breast lesions and to evaluate the results according to the mode of detection of the target lesions. METHODS: This is a retrospective review of 703 consecutive women who underwent US-CNB for screen-detected breast lesions at a single tertiary hospital. Breast Imaging Reporting and Data System (BI-RADS) categories and histopathological results of the target lesions were assessed...
February 9, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28181826/a-new-method-for-the-prevention-of-skin-laceration-during-vacuum-assisted-breast-biopsy
#4
Juan D Berna, Florentina Guzmán-Aroca, Juan de Dios Berná-Mestre, Dolores Hernández-Gómez
OBJECTIVE: To describe a new technique to prevent skin laceration during ultrasound-guided vacuum-assisted breast biopsy (VABB) with the insertion of a spinal needle between the mass and the skin. METHODS: The study includes 118 patients with 118 BI-RADS 3 masses located very close to the skin or areola, which were excised using the Mammotome system with a spinal needle inserted just above the site of insertion of the probe. RESULTS: The mean distance between the most superficial portion of the mass to the under surface of the overlying skin was 1...
February 9, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28181343/apparent-diffusion-coefficient-values-may-help-predict-which-mri-detected-high-risk-breast-lesions-will-upgrade-at-surgical-excision
#5
Safia Cheeney, Habib Rahbar, Brian N Dontchos, Sara H Javid, Mara H Rendi, Savannah C Partridge
PURPOSE: To investigate whether diffusion-weighted imaging (DWI) features could assist in determining which high-risk lesions identified on dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) and diagnosed on core needle biopsy (CNB) will upgrade to malignancy on surgical excision. MATERIALS AND METHODS: This Institutional Review Board (IRB)-approved prospective study included participants with MRI-detected Breast Imaging Reporting and Data System (BI-RADS) 4 or 5 lesions with high-risk pathology on CNB who underwent surgical excision...
February 9, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28161786/quantification-of-masking-risk-in-screening-mammography-with-volumetric-breast-density-maps
#6
Katharina Holland, Carla H van Gils, Ritse M Mann, Nico Karssemeijer
PURPOSE: Fibroglandular tissue may mask breast cancers, thereby reducing the sensitivity of mammography. Here, we investigate methods for identification of women at high risk of a masked tumor, who could benefit from additional imaging. METHODS: The last negative screening mammograms of 111 women with interval cancer (IC) within 12 months after the examination and 1110 selected normal screening exams from women without cancer were used. From the mammograms, volumetric breast density maps were computed, which provide the dense tissue thickness for each pixel location...
February 4, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28160525/automatic-intensity-windowing-of-mammographic-images-based-on-a-perceptual-metric
#7
Alberto Albiol, Alberto Corbi, Francisco Albiol
PURPOSE: Initial auto-adjustment of the window level WL and width WW applied to mammo-graphic images. The proposed intensity windowing (IW) method is based on the maximization of the mutual information (MI) between a perceptual decomposition of the original 12-bit sources and their screen displayed 8-bit version. Besides zoom, color inversion and panning operations, IW is the most commonly performed task in daily screening and has a direct impact on diagnosis and the time involved in the process...
February 4, 2017: Medical Physics
https://www.readbyqxmd.com/read/28154989/can-strain-elastography-combined-with-ultrasound-breast-imaging-reporting-and-data-system-be-a-more-effective-method-in-the-differentiation-of-benign-and-malignant-breast-lesions
#8
Serdar Arslan, Nihal Uslu, Funda Ulu Ozturk, Eda Yilmaz Akcay, Tugan Tezcaner, Ahmet Muhtesem Agildere
PURPOSE: To investigate whether a novel method that combines breast imaging reporting and data system (BI-RADS) with strain elastography contributes to diagnostic performance in differentiation of malignant and benign breast lesions. METHODS: In 81 patients, 81 breast lesions were prospectively investigated. Breast lesions were separately evaluated with ultrasonography and strain elastography. While evaluations with ultrasonography were based on 2003 BI-RADS-US, strain elastography evaluations were based on a 5-point scale and strain ratio...
February 2, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28152151/population-attributable-risk-proportion-of-clinical-risk-factors-for-breast-cancer
#9
Natalie J Engmann, Marzieh K Golmakani, Diana L Miglioretti, Brian L Sprague, Karla Kerlikowske
Importance: Many established breast cancer risk factors are used in clinical risk prediction models, although the proportion of breast cancers explained by these factors is unknown. Objective: To determine the population-attributable risk proportion (PARP) for breast cancer associated with clinical breast cancer risk factors among premenopausal and postmenopausal women. Design, Setting, and Participants: Case-control study with 1:10 matching on age, year of risk factor assessment, and Breast Cancer Surveillance Consortium (BCSC) registry...
February 2, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28143431/mammographic-breast-density-and-risk-of-breast-cancer-in-women-with-atypical-hyperplasia-an-observational-cohort-study-from-the-mayo-clinic-benign-breast-disease-bbd-cohort
#10
Robert A Vierkant, Amy C Degnim, Derek C Radisky, Daniel W Visscher, Ethan P Heinzen, Ryan D Frank, Stacey J Winham, Marlene H Frost, Christopher G Scott, Matthew R Jensen, Karthik Ghosh, Armando Manduca, Kathleen R Brandt, Dana H Whaley, Lynn C Hartmann, Celine M Vachon
BACKGROUND: Atypical hyperplasia (AH) and mammographic breast density (MBD) are established risk factors for breast cancer (BC), but their joint contributions are not well understood. We examine associations of MBD and BC by histologic impression, including AH, in a subcohort of women from the Mayo Clinic Benign Breast Disease Cohort. METHODS: Women with a diagnosis of BBD and mammogram between 1985 and 2001 were eligible. Histologic impression was assessed via pathology review and coded as non-proliferative disease (NP), proliferative disease without atypia (PDWA) and AH...
January 31, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28132392/determinants-of-volumetric-breast-density-in-chilean-premenopausal-women
#11
Ana Pereira, Maria Luisa Garmendia, Ricardo Uauy, Paulina Neira, Sandra Lopez-Arana, Serghei Malkov, John Shepherd
PURPOSE: High mammographic breast density (BD) is a strong risk factor of breast cancer; however, little is known in women under 40 years of age. Recently, dual-energy X-ray Absorptiometry (DXA) has been developed as a low-dose method to measure BD in young populations. Thus, our aims were to describe BD in relation to risk factors in Chilean women under 40 years old and to explore the equivalence of DXA to mammography for the measurement of BD. METHODS: We selected 192 premenopausal Chilean female participants of the DERCAM study for whom we have anthropometric, sociodemographic, and gyneco-obstetric data...
January 28, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28131457/bi-rads-%C3%A2-fifth-edition-a-summary-of-changes
#12
D A Spak, J S Plaxco, L Santiago, M J Dryden, B E Dogan
The Breast Imaging Reporting and Data System (BI-RADS(®)) is a standardized system of reporting breast pathology as seen on mammogram, ultrasound, and magnetic resonance imaging. It encourages consistency between reports and facilitates clear communication between the radiologist and other physicians by providing a lexicon of descriptors, a reporting structure that relates assessment categories to management recommendations, and a framework for data collection and auditing. This article highlights the changes made to the BI-RADS(®) atlas 5th edition by comparison with its predecessor, provide a useful resource for a radiologist attempting to review the recent changes to the new edition, and serve as a quick reference to those who have previously become familiar with the material...
January 25, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28120030/comparison-between-automated-breast-volume-scanner-abvs-versus-hand-held-ultrasound-as-a-second-look-procedure-after-magnetic-resonance-imaging
#13
Rossano Girometti, Martina Zanotel, Viviana Londero, Massimo Bazzocchi, Chiara Zuiani
OBJECTIVES: To evaluate the agreement between automated breast volume scanner (ABVS) and conventional ultrasound (US) as a second-look (SL) tool for assessing additional findings found on MRI. METHODS: Over a 7-month period, we prospectively assigned to SL-US and SL-ABVS all patients undergoing 1.5 T breast MRI in whom additional findings were found. Five experienced breast radiologists independently interpreted SL-US and SL-ABVS in blinded sessions to evaluate the detection rate of MRI findings and assign them to BI-RADS categories...
January 24, 2017: European Radiology
https://www.readbyqxmd.com/read/28099938/bi-rads-3-5-microcalcifications-can-preoperatively-predict-breast-cancer-her2-and-luminal-a-molecular-subtype
#14
DongZhi Cen, Li Xu, Ningna Li, Zhiguang Chen, Lu Wang, Shuqin Zhou, Biao Xu, Chun Ling Liu, Zaiyi Liu, Tingting Luo
PURPOSE: To investigate associations between breast cancer molecular subtype and the patterns of mammographically detected calcifications. RESULTS: Identified were 93 (19.1%) Luminal A, 242 (49.9%) Luminal B, 108 (22.2%) HER2 and 42 (8.7%) basal subtypes. In univariate analysis, the clinicopathological parameters and BI-RADS 3-5 microcalcifications, which consisted 9 selected features was significantly associated with breast cancer molecular subtype (all P < 0...
January 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/28075608/sonographic-appearance-of-lesions-diagnosed-as-lobular-neoplasia-at-sonographically-guided-biopsies
#15
Romuald Ferré, Atilla Omeroglu, Benoît Mesurolle
OBJECTIVE: The objective of our study was to review the sonographic features of breast lesions yielding lobular neoplasia (LN) at sonographically guided biopsy, evaluate the surgical pathology outcome of these lesions, and determine if imaging findings or clinical features can be used to predict an upgrade to malignancy. MATERIALS AND METHODS: Of the 8205 sonographically guided breast biopsies (14-gauge cores) performed from 2007 through 2014, 22 yielded a diagnosis of LN, which means that LN was the most severe pathologic lesion...
January 11, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28067435/mr-imaging-findings-in-molecular-subtypes-of-breast-cancer-according-to-birads-system
#16
Lidia Navarro Vilar, Salvador Pascual Alandete Germán, Rosana Medina García, Esther Blanc García, Natalia Camarasa Lillo, José Vilar Samper
To evaluate magnetic resonance imaging (MRI) findings, according to Breast Imaging-Reporting and Data System (BI-RADS), and to relate them with molecular subtypes of breast cancer. The MRI findings were reviewed retrospectively in 201 women diagnosed of invasive breast cancer confirmed by surgery and were compared with the molecular subtypes. Following the BI-RADS, MRI findings included disease type, size, enhancement, morphology and contrast kinetics. In mass-like lesion types were studied shape, margin and enhancement, and in nonmass-like lesion types, distribution modifiers and internal enhancement...
January 9, 2017: Breast Journal
https://www.readbyqxmd.com/read/28065370/a-new-qualitative-pattern-classification-of-shear-wave-elastograghy-for-solid-breast-mass-evaluation
#17
Rui Cong, Jing Li, Song Guo
OBJECTIVES: To examine the efficacy of qualitative shear wave elastography (SWE) in the classification and evaluation of solid breast masses, and to compare this method with conventional ultrasonograghy (US), quantitative SWE parameters and qualitative SWE classification proposed before. METHODS: From April 2015 to March 2016, 314 consecutive females with 325 breast masses who decided to undergo core needle biopsy and/or surgical biopsy were enrolled. Conventional US and SWE were previously performed in all enrolled subjects...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28048929/su-c-207b-04-automated-segmentation-of-pectoral-muscle-in-mr-images-of-dense-breasts
#18
E Verburg, S N de Waard, W B Veldhuis, C H van Gils, Kga Gilhuijs
PURPOSE: To develop and evaluate a fully automated method for segmentation of the pectoral muscle boundary in Magnetic Resonance Imaging (MRI) of dense breasts. METHODS: Segmentation of the pectoral muscle is an important part of automatic breast image analysis methods. Current methods for segmenting the pectoral muscle in breast MRI have difficulties delineating the muscle border correctly in breasts with a large proportion of fibroglandular tissue (i.e., dense breasts)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047013/we-de-207b-12-scatter-correction-for-dedicated-cone-beam-breast-ct-based-on-a-forward-projection-model
#19
L Shi, S Vedantham, A Karellas, L Zhu
PURPOSE: The image quality of dedicated cone-beam breast CT (CBBCT) is fundamentally limited by substantial x-ray scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose to suppress x-ray scatter in CBBCT images using a deterministic forward projection model. METHOD: We first use the 1st-pass FDK-reconstructed CBBCT images to segment fibroglandular and adipose tissue...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28042590/breast-density-estimation-from-high-spectral-and-spatial-resolution-mri
#20
Hui Li, William A Weiss, Milica Medved, Hiroyuki Abe, Gillian M Newstead, Gregory S Karczmar, Maryellen L Giger
A three-dimensional breast density estimation method is presented for high spectral and spatial resolution (HiSS) MR imaging. Twenty-two patients were recruited (under an Institutional Review Board--approved Health Insurance Portability and Accountability Act-compliant protocol) for high-risk breast cancer screening. Each patient received standard-of-care clinical digital x-ray mammograms and MR scans, as well as HiSS scans. The algorithm for breast density estimation includes breast mask generating, breast skin removal, and breast percentage density calculation...
October 2016: Journal of Medical Imaging
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