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Mohammad Rawashdeh, Sarah Lewis, Maha Zaitoun, Patrick Brennan
BACKGROUND: While there is much literature describing the radiologic detection of breast cancer, there are limited data available on the agreement between experts when delineating and classifying breast lesions. The aim of this work is to measure the level of agreement between expert radiologists when delineating and classifying breast lesions as demonstrated through Breast Imaging Reporting and Data System (BI-RADS) and quantitative shape metrics. METHODS: Forty mammographic images, each containing a single lesion, were presented to nine expert breast radiologists using a high specification interactive digital drawing tablet with stylus...
April 13, 2018: Computers in Biology and Medicine
Paola Clauser, Matthias Dietzel, Michael Weber, Clemens G Kaiser, Pascal At Baltzer
Background Motion artifacts can reduce image quality of breast magnetic resonance imaging (MRI). There is a lack of data regarding their effect on diagnostic estimates. Purpose To evaluate factors that potentially influence readers' diagnostic estimates in breast MRI: motion artifacts; amount of fibroglandular tissue; background parenchymal enhancement; lesion size; and lesion type. Material and Methods This Institutional Review Board-approved, retrospective, cross-sectional, single-center study included 320 patients (mean age = 55...
January 1, 2018: Acta Radiologica
Gisela L G Menezes, Ruud M Pijnappel, Carla Meeuwis, Robertus Bisschops, Jeroen Veltman, Philip T Lavin, Marc J van de Vijver, Ritse M Mann
Purpose To assess the ability of optoacoustic (OA) ultrasonography (US) to help correctly downgrade benign masses classified as Breast Imaging Reporting and Data System (BI-RADS) 4a and 4b to BI-RADS 3 or 2. Materials and Methods OA/US technology uses laser light to detect relative amounts of oxygenated and deoxygenated hemoglobin in and around suspicious breast masses. In this prospective, multicenter study, results of 209 patients with 215 breast masses classified as BI-RADS 4a or 4b at US are reported. Patients were enrolled between 2015 and 2016...
April 17, 2018: Radiology
Ashley I Huppe, Marc F Inciardi, Mark Redick, Melissa Carroll, Jennifer Buckley, Jacqueline D Hill, Jason B Gatewood
RATIONALE AND OBJECTIVES: This study aimed to determine the average time for breast radiologists of varied experience to interpret automated breast ultrasound (ABUS) examinations. MATERIALS AND METHODS: A reader performance study was conducted on female patients, with ACR BI-RADS 4 breast density classifications of C or D, who received both an ABUS screening examination and a digital mammogram from 2013 to 2014 at an academic institution. Three faculty breast radiologists with varied levels of ABUS experience (advanced, intermediate, novice) read all ABUS examinations, with interpretation times and final impressions (categorized as "normal" or "abnormal") recorded for each examination...
April 13, 2018: Academic Radiology
Qing Zhao, Xiao-Lei Wang, Jia-Wei Sun, Zhao-Peng Jiang, Lin Tao, Xian-Li Zhou
OBJECTIVES: To compare the diagnostic performance of conventional strain elastography (CSE) and acoustic radiation force impulse (ARFI) induced SE for qualitative assessment of breast lesions and evaluate the additional value of the two techniques combined with Breast Imaging Reporting and Data System (BI-RADS) respectively for the differentiation of benign and malignant breast lesions. METHODS: In a cohort of 110 women, the conventional ultrasound (US) features and the elasticity scores of CSE and ARFI induced SE were recorded...
April 13, 2018: Clinical Hemorheology and Microcirculation
Ying Zhang, Hui-Xiong Xu, Chong-Ke Zhao, Xiao-Long Li, Xiao-Wan Bo, Ya-Ping He, Bo-Ji Liu, Dan Wang, Wei-Wei Ren
OBJECTIVE: To assess the performance of conventional high frequency ultrasound (US) and US elastography in diagnosis of complex cystic and solid breast lesions. METHODS: Ninety three lesions in 93 patients underwent conventional US and US elastography, including strain elastography, acoustic radiation force impulse (ARFI) imaging, and point shear wave speed (SWS) measurement. RESULTS: Pathological examination revealed 31 (33.3%) of the 93 lesions were malignant and the remaining 62 (66...
April 13, 2018: Clinical Hemorheology and Microcirculation
Su Min Ha, Eun Young Chae, Joo Hee Cha, Hee Jung Shin, Woo Jung Choi, Hak Hee Kim
OBJECTIVE: To determine the frequency and malignancy rate among growing Breast Imaging Reporting and Data System (BI-RADS) category 3 lesions diagnosed on follow-up breast ultrasound (US) and to evaluate the radiological and clinical features associated with malignancy. METHODS: Of the 38,482 women who underwent breast US between January 2010 and December 2011, 11,582 (30.1%) patients had 12,514 BI-RADS category 3 lesions. Patients whose lesions showed ≥20% enlargement on follow-up US were selected for this study...
April 16, 2018: British Journal of Radiology
William C Strohsnitter, Kimberly A Bertrand, Rebecca Troisi, Christopher G Scott, Andrea L Cheville, Robert N Hoover, Julie R Palmer, Celine M Vachon
In a prospective cohort study of the health effects associated with prenatal Diethylstilbestrol (DES) exposure, DES was associated with an increased breast cancer risk after 40 years of age. It is unknown whether it is associated with greater mammographic density, which strongly predicts breast cancer risk. A cohort of DES-exposed and unexposed women was assembled at the Mayo Clinic in 1975, and followed through 2012 as part of the National Cancer Institute's DES Follow-up Study. Mammographic density from 3,637 mammograms for 332 (222 DES-exposed, 110 unexposed) women in this cohort screened at the Mayo Clinic, Rochester between 1996 and 2015 were determined clinically using the Breast Imaging Reporting and Data System (BI-RADS)...
April 15, 2018: International Journal of Cancer. Journal International du Cancer
Dandan Liu, Zhaogui Ba, Xiaoli Ni, Linhong Wang, Dexin Yu, Xiangxing Ma
BACKGROUND This study aims to subdivide BI-RADS-MRI (Breast Imaging Reporting and Data System Magnetic Resonance Imaging) Category 4 lesions and to evaluate the role of Fischer's scoring system, apparent diffusion coefficient (ADC), and Fischer's + ADC in differential diagnosis of breast lesions. MATERIAL AND METHODS This study retrospectively analyzed the data of 143 patients (150 breast lesions), who were diagnosed by biopsy, and received dynamic contrast enhancement and diffusion-weighted imaging. The diagnostic efficacies of ADC, Fischer's scoring system, and the Fischer's + ADC were analyzed by the receiver operating characteristics curve...
April 12, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
R Jared Weinfurtner, Bethany Niell, Yasmin Mekhail, Emily Aguila, Leena Kamat
BACKGROUND: Women with breast imaging often seek second opinions at tertiary care centers. Our study measures the frequency of discrepancy between initial and second opinion breast imaging recommendations and evaluates the impact on patient management. MATERIALS AND METHODS: A retrospective chart review was conducted on 504 consecutive patients with second opinion breast radiology interpretations performed by 6 sub-specialized breast radiologists at a dedicated cancer center from January 1, 2014 through September 1, 2014...
March 16, 2018: Clinical Breast Cancer
Romuald Ferre, Pierre-Alain Goumot, Benoît Mesurolle
OBJECTIVES: To assess the benefit of stereoscopic digital mammography in daily practice. METHODS: Stereoscopic digital (SD) mammography allows a fused 3D view of mammogram. A 4-degree cranio-caudal (CC) angle view matched with a regular CC view allows generating a stereoscopic view Three breast radiologists reviewed retrospectively 1,110 stereoscopic digital mammograms (1075 women) performed between November 2011 and February 2013 with the following sequence: each evaluated firstly conventional mammogram alone, and then integrated SD mammograms...
April 2, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Matthias Dietzel, Pascal A T Baltzer
Due to its superior sensitivity, breast MRI (bMRI) has been established as an important additional diagnostic tool in the breast clinic and is used for screening in patients with an elevated risk for breast cancer. Breast MRI, however, is a complex tool, providing multiple images containing several contrasts. Thus, reading bMRI requires a structured approach. A lack of structure will increase the rate of false-positive findings and sacrifice most of the advantages of bMRI as additional work-up will be required...
April 3, 2018: Insights Into Imaging
Lars J Grimm, Rebecca A Shelby, Emily E Knippa, Eun L Langman, Lauren S Miller, Beth E Whiteside, Mary Scott C Soo
PURPOSE: To determine women's perceptions of breast cancer risk and thresholds for desiring biopsy when considering BI-RADS 3 and 4A scenarios and recommendations, respectively. MATERIALS AND METHODS: Women presenting for screening mammography from five geographically diverse medical centers were surveyed. Demographic information and baseline anxiety were queried. Participants were presented with scenarios of short-term imaging follow-up recommendations (ie, BI-RADS 3) and biopsy recommendations (ie, BI-RADS 4A) for low-risk mammographic abnormalities and asked to estimate their breast cancer risk for each scenario...
March 29, 2018: Journal of the American College of Radiology: JACR
L Martí-Bonmatí, E Ruiz-Martínez, A Ten, A Alberich-Bayarri
Nowadays, the images and information generated in imaging tests, as well as the reports that are issued, are digital and represent a reliable source of data. Reports can be classified according to their content and to the type of information they include into three main types: organized (free text in natural language), predefined (with templates and guidelines elaborated with previously determined natural language like that used in BI-RADS and PI-RADS), or structured (with drop-down menus displaying questions with various possible answers that have been agreed on with the rest of the multidisciplinary team, which use standardized lexicons and are structured in the form of a database with data that can be traced and exploited with statistical tools and data mining)...
March 28, 2018: Radiología
Hai-Lin Park, Ka Young Kim, Jong Seob Park, Ji-Eun Shin, Hye-Rin Kim, Bora Yang, Ji-Young Kim, Jeong Yun Shim, Eun-Ah Shin, Song-Mi Noh
BACKGROUND/AIM: To evaluate the usefulness and safety of vacuum-assisted breast biopsy (VABB) for breast lesion diagnosis and treatment. PATIENTS AND METHODS: Clinical and histopathological data of 8,748 patients, who underwent 11,221 VABB procedures were analyzed. RESULTS: Most patients (58.2%) were <40 years old. Most lesions (39.6%) were 0.6-1.0 cm in diameter while 3.2% were ≥3.0 cm; fibroadenomas were the most common (46.6%). Eight (14% of 57) cases of atypical ductal hyperplasia were underestimated...
April 2018: Anticancer Research
Susanne Wienbeck, Uwe Fischer, Susanne Luftner-Nagel, Joachim Lotz, Johannes Uhlig
OBJECTIVES: To evaluate the diagnostic accuracy of contrast-enhanced (CE) cone-beam breast computed tomography (CBBCT) in dense breast tissue and compare it to non-contrast (NC) CBBCT, mammography (MG) and magnetic resonance imaging (MRI). METHODS: This prospective institutional review board-approved study included 41 women (52 breasts) with American College of Radiology (ACR) density types c or d and Breast Imaging Reporting and Data System (BI-RADS) 4 or 5 assessments in MG or ultrasound (US)...
March 28, 2018: European Radiology
Taghreed I Alshafeiy, Jonathon V Nguyen, Carrie M Rochman, Brandi T Nicholson, James T Patrie, Jennifer A Harvey
Purpose To compare the outcome of architectural distortion (AD) without associated mass only on digital breast tomosynthesis (DBT) with AD seen at two-dimensional (2D) mammography and to evaluate if the incidence of malignancy is influenced by the presence of a correlate at ultrasonography (US). Materials and Methods This retrospective study had institutional review board approval and was HIPAA compliant. All consecutive cases in which patients with AD were ultimately assigned Breast Imaging Reporting and Data System (BI-RADS) 4 or 5 categories from 2009 to 2016 were reviewed by three readers for visibility (2D vs DBT)...
March 27, 2018: Radiology
Faina Nakhlis
PURPOSE OF REVIEW: The aim of this review is to summarize recently published literature addressing atypical ductal hyperplasia (ADH), lobular neoplasia (atypical lobular hyperplasia [ALH] and classic lobular carcinoma in situ [C-LCIS]), non-classic lobular carcinoma in situ (NC-LCIS), papillary lesions, and flat epithelial atypia (FEA). RECENT FINDINGS: While ADH, ALN, and C-LCIS are well-established markers of an increased risk of future breast cancers, the risk implications are less clear for papillary lesions and FEA...
March 23, 2018: Current Oncology Reports
Tommaso Vincenzo Bartolotta, Alessia Orlando, Vito Cantisani, Domenica Matranga, Raffele Ienzi, Alessandra Cirino, Francesco Amato, Maria Laura Di Vittorio, Massimo Midiri, Roberto Lagalla
No abstract text is available yet for this article.
March 22, 2018: La Radiologia Medica
Wei-Hsin Yuan, Anna Fen-Yau Li, Yi-Hong Chou, Hui-Chen Hsu, Ying-Yuan Chen
OBJECTIVE: The purpose of this study was to determine clinical and ultrasonographic characteristics of male breast tumors. METHODS: The medical records of male patients with breast lesions were retrieved from an electronic medical record database and a pathology database and retrospectively reviewed. A total of 112 men (125 breast masses) with preoperative breast ultrasonography (US) were included (median age, 59.50 years; age range, 15-96 years). Data extracted included patient age, if the lesions were bilateral, palpable, and tender, and the presence of nipple discharge...
2018: PloS One
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