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https://www.readbyqxmd.com/read/29332513/the-meaning-of-choosing-a-spouse-among-ultra-orthodox-jewish-women-who-found-themselves-in-a-violent-relationship
#1
Tova Band-Winterstein, Ilanit Tuito
This research note addresses how ultra-Orthodox Jewish women in Israel coping with intimate partner violence experienced the spouse selection process. In-depth semistructured qualitative-phenomenological interviews were conducted with 17 women. Four major themes emerged: (a) "The matchmaker seemingly fell asleep on her watch"; (b) The parents' mistakes; (c) "The rabbi told me to jump into the water. Now he should hand me the paddles to get out!" The rabbi's role; and (d) "That's it . . . I follow it blindly": The system...
August 1, 2017: Violence Against Women
https://www.readbyqxmd.com/read/29240603/what-is-the-optimal-adjuvant-treatment-sequence-for-node-positive-endometrial-cancer-results-of-a-national-cancer-database-analysis
#2
Ankit Modh, Ahmed I Ghanem, Charlotte Burmeister, Rabbie K Hanna, Mohamed A Elshaikh
OBJECTIVE: The optimal sequence of administering chemotherapy (CT) and radiation treatment (RT) in women with node-positive endometrial carcinoma (EC) remains controversial. We used the National Cancer Database to evaluate overall survival (OS) in women with advanced EC receiving different sequences of adjuvant therapy. METHODS: The National Cancer Database was queried for female adults with International Federation of Gynecology and Obstetrics 2009 stage IIIC1 to IIIC2 EC diagnosed from 2004 to 2012 treated with hysterectomy and adjuvant CT and RT...
December 13, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29206216/bioactive-steroids-and-saponins-of-the-genus-trillium
#3
REVIEW
Shafiq Ur Rahman, Muhammad Ismail, Muhammad Khurram, Irfan Ullah, Fazle Rabbi, Marcello Iriti
The species of the genus Trillium (Melanthiaceae alt. Trilliaceae) include perennial herbs with characteristic rhizomes mainly distributed in Asia and North America. Steroids and saponins are the main classes of phytochemicals present in these plants. This review summarizes and discusses the current knowledge on their chemistry, as well as the in vitro and in vivo studies carried out on the extracts, fractions and isolated pure compounds from the different species belonging to this genus, focusing on core biological properties, i...
December 5, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29202685/accuracies-of-univariate-and-multivariate-genomic-prediction-models-in-african-cassava
#4
Uche Godfrey Okeke, Deniz Akdemir, Ismail Rabbi, Peter Kulakow, Jean-Luc Jannink
BACKGROUND: Genomic selection (GS) promises to accelerate genetic gain in plant breeding programs especially for crop species such as cassava that have long breeding cycles. Practically, to implement GS in cassava breeding, it is necessary to evaluate different GS models and to develop suitable models for an optimized breeding pipeline. In this paper, we compared (1) prediction accuracies from a single-trait (uT) and a multi-trait (MT) mixed model for a single-environment genetic evaluation (Scenario 1), and (2) accuracies from a compound symmetric multi-environment model (uE) parameterized as a univariate multi-kernel model to a multivariate (ME) multi-environment mixed model that accounts for genotype-by-environment interaction for multi-environment genetic evaluation (Scenario 2)...
December 4, 2017: Genetics, Selection, Evolution: GSE
https://www.readbyqxmd.com/read/29190205/hypertension-regulating-angiotensin-peptides-in-the-pathobiology-of-cardiovascular-disease
#5
Misbah Hussain, Fazli Rabbi Awan
Renin angiotensin system (RAS) is an endogenous hormone system involved in the control of blood pressure and fluid volume. Dysregulation of RAS has a pathological role in causing cardiovascular diseases through hypertension. Among several key components of RAS, angiotensin peptides, varying in amino acid length and biological function, have important roles in preventing or promoting hypertension, cardiovascular diseases, stroke, vascular remodeling etc. These peptides are generated by the metabolism of inactive angiotensinogen or its derived peptides by hydrolyzing action of certain enzymes...
November 30, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29177209/h-pylori-infection-and-gastric-cancer-in-bangladesh-a-case-control-study
#6
Khandker Kawser Sarker, Md Jahangir Kabir, A K M Minhaj Uddin Bhuyian, Md Shahjadul Alam, Fazle Rabbi Chowdhury, M Abdul Ahad, Md Anisur Rahman, M Mizanur Rahman
Background: Like that of other Asian countries gastric cancer (GC) is also a leading cancer in Bangladesh and also a cause for cancer-related mortality. Infection with Helicobacter pylori (H. pylori) is the strongest recognized risk factor for gastric adenocarcinoma. The infection is also prevalent in common people. This case-control study was carried out to find an association between GC and H. pylori infection in the community. Materials and Methods: To evaluate association of H...
November 2017: International Journal of Surgery. Oncology
https://www.readbyqxmd.com/read/29162095/how-are-compassion-fatigue-burnout-and-compassion-satisfaction-affected-by-quality-of-working-life-findings-from-a-survey-of-mental-health-staff-in-italy
#7
Gaia Cetrano, Federico Tedeschi, Laura Rabbi, Giorgio Gosetti, Antonio Lora, Dario Lamonaca, Jill Manthorpe, Francesco Amaddeo
BACKGROUND: Quality of working life includes elements such as autonomy, trust, ergonomics, participation, job complexity, and work-life balance. The overarching aim of this study was to investigate if and how quality of working life affects Compassion Fatigue, Burnout, and Compassion Satisfaction among mental health practitioners. METHODS: Staff working in three Italian Mental Health Departments completed the Professional Quality of Life Scale, measuring Compassion Fatigue, Burnout, and Compassion Satisfaction, and the Quality of Working Life Questionnaire...
November 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29130476/graft-versus-host-disease-in-a-pediatric-multiple-organ-transplant-recipient-with-trichohepatoenteric-syndrome-a-unique-case-report
#8
Pooja H Rambhia, Rabbi Hanna, Wilma F Bergfeld
No abstract text is available yet for this article.
November 11, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29119267/ppors-an-ancient-type-iii-polyketide-synthase-is-required-for-integrity-of-leaf-cuticle-and-resistance-to-dehydration-in-the-moss-physcomitrella-patens
#9
Li Li, Misbah Aslam, Fazle Rabbi, Mark C Vanderwel, Neil W Ashton, Dae-Yeon Suh
PpORS knockout mutants produced abnormal leaves with increased dye permeability and were more susceptible to dehydration, consistent with PpORS products being constituents of a cuticular structure in the moss. Type III polyketide synthases (PKSs) have co-evolved with terrestrial plants such that each taxon can generate a characteristic collection of polyketides, fine-tuned to its needs. 2'-Oxoalkylresorcinol synthase from Physcomitrella patens (PpORS) is basal to all plant type III PKSs in phylogenetic trees and may closely resemble their most recent common ancestor...
November 8, 2017: Planta
https://www.readbyqxmd.com/read/29110586/genetic-variants-of-sult1a1-and-xrcc1-genes-and-risk-of-lung-cancer-in-bangladeshi-population
#10
Tasnova Tasnim, Mir Md Abdullah Al-Mamun, Noor Ahmed Nahid, Md Reazul Islam, Mohd Nazmul Hasan Apu, Most Umme Bushra, Sikder Nahidul Islam Rabbi, Zabun Nahar, Jakir Ahmed Chowdhury, Maizbha Uddin Ahmed, Mohammad Safiqul Islam, Abul Hasnat
Lung cancer is one of the most frequently occurring cancers throughout the world as well as in Bangladesh. This study aimed to correlate the prognostic and/or predictive value of functional polymorphisms in SULT1A1 (rs9282861) and XRCC1 (rs25487) genes and lung cancer risk in Bangladeshi population. A case-control study was conducted which comprises 202 lung cancer patients and 242 healthy volunteers taking into account the age, sex, and smoking status. After isolation of genomic DNA, genotyping was done by polymerase chain reaction-restriction fragment length polymorphism method and the lung cancer risk was evaluated as odds ratio that was adjusted for age, sex, and smoking status...
November 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/29109156/improving-genomic-prediction-in-cassava-field-experiments-using-spatial-analysis
#11
Ani A Elias, Ismail Rabbi, Peter Kulakow, Jean-Luc Jannink
Cassava (Manihot esculenta Crantz) is an important staple food in sub-Saharan Africa. Breeding experiments were conducted at the International Institute of Tropical Agriculture in cassava to select elite parents. Taking into account the heterogeneity in the field while evaluating these trials can increase the accuracy in estimation of breeding values. We used an exploratory approach using the parametric spatial kernels Power, Spherical, and Gaussian to determine the best kernel for a given scenario. The spatial kernel was fit simultaneously with a genomic kernel in a genomic selection model...
November 6, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29094226/aminoacidopathies-prevalence-etiology-screening-and-treatment-options
#12
REVIEW
Muhammad Wasim, Fazli Rabbi Awan, Haq Nawaz Khan, Abdul Tawab, Mazhar Iqbal, Hina Ayesha
Inborn errors of metabolism (IEMs) are a group of inherited metabolic disorders which are caused by mutations in the specific genes that lead to impaired proteins or enzymes production. Different metabolic pathways are perturbed due to the deficiency or lack of enzymes. To date, more than 500 IEMs have been reported with most of them being untreatable. However, fortunately 91 such disorders are potentially treatable, if diagnosed at an earlier stage of life. IEMs have been classified into different categories and one class of IEMs, characterized by the physiological disturbances of amino acids is called as aminoacidopathies...
November 1, 2017: Biochemical Genetics
https://www.readbyqxmd.com/read/29082780/textual-healing-tailor-made-kabbalistic-therapeutics-in-jerusalem
#13
Shlomo Guzmen-Carmali, Asaf Sharabi
This paper, based on fieldwork conducted in a Jerusalem yeshiva, describes how the yeshiva, a traditional institute of religious studies, also serves as an institution of healing and personal therapy in which sacred religious texts assume a central place. The article focuses on personal sessions between the rabbi who heads the yeshiva, and his audience of believers who turn to him for help in coping with personal hardships and tribulations. The paper contextualizes and elaborates upon the concept of 'deep healing' to describe how the rabbi uses his regular 'tool kit' to diagnose the problems of the person facing him and to offer optimal, personalized therapy...
October 30, 2017: Anthropology & Medicine
https://www.readbyqxmd.com/read/29058472/a-case-control-association-study-of-ace-gene-polymorphism-i-d-with-hypertension-in-punjabi-population-from-faisalabad-pakistan
#14
Misbah Hussain, Fazli Rabbi Awan, Amna Gujjar, Shakir Hafeez, Mehboob Islam
Angiotensin converting enzyme (ACE) is a key component of renin angiotensin aldosterone system. It converts angiotensin I to angiotensin II. Insertion/deletion (I/D) polymorphism of ACE gene is found associated with several complications. However, its association with hypertension and related metabolic diseases is still controversial. So, the aim of the present study was to check this association for Punjabi population from Faisalabad, Pakistan. For this purpose, blood samples (patients = 100, controls = 48) were collected and several biochemical parameters were measured...
October 23, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/29056570/activity-and-safety-of-azd3759-in-egfr-mutant-non-small-cell-lung-cancer-with-cns-metastases-bloom-a-phase-1-open-label-dose-escalation-and-dose-expansion-study
#15
Myung-Ju Ahn, Dong-Wan Kim, Byoung Chul Cho, Sang-We Kim, Jong Seok Lee, Jin-Seok Ahn, Tae Min Kim, Chia-Chi Lin, Hye Ryun Kim, Thomas John, Steven Kao, Jonathan W Goldman, Wu-Chou Su, Ronald Natale, Sarit Rabbie, Bryony Harrop, Philip Overend, Zhenfan Yang, James Chih-Hsin Yang
BACKGROUND: CNS metastases-including brain and leptomeningeal metastases-from epidermal growth factor receptor (EGFR)-mutant non-small-cell lung cancer (NSCLC) are associated with poor prognosis. AZD3759 is a novel EGFR tyrosine kinase inhibitor with high capability to penetrate the blood-brain barrier. We aimed to assess the safety, tolerability, pharmacokinetics, and efficacy of AZD3759 in patients with EGFR-mutant NSCLC with brain and leptomeningeal metastases. METHODS: This open-label, multicentre, phase 1 study was undertaken at 11 centres and hospitals in Australia, South Korea, Taiwan, and the USA...
November 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/29037871/moringa-oleifera-seed-lectin-inhibits-ehrlich-ascites-carcinoma-cell-growth-by-inducing-apoptosis-through-the-regulation-of-bak-and-nf-%C3%AE%C2%BAb-gene-expression
#16
A K M Asaduzzaman, Imtiaj Hasan, Aninda Chakrabortty, Sadnima Zaman, Shaikh Shohidul Islam, Fazle Rabbi Shakil Ahmed, K M Ahsanul Kabir, Md Nurujjaman, Md Belal Uddin, Mohammad Taufiq Alam, Ranajit Kumar Shaha, Syed Rashel Kabir
A Moringa oleifera seed lectin (MOSL) was purified by using chitin column with the molecular mass of 17±1kDa. The lectin agglutinated mouse, cow and human erythrocytes and the hemagglutination activity was inhibited by methyl-α-d-mannopyranoside, methyl-β-d-galactopyranoside, lactose and glucose. The lectin exhibited 100% hemagglutination activity at the pH range from 8.0 to 9.0 and temperature range from 30 to 60°C. Additionally, the lectin gradually lost its activity in the presence of urea but the activity abolish completely when treated with EDTA...
October 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29028367/philip-hillkowitz-the-granddaddy-of-medical-technologists-and-cofounder-of-the-american-society-for-clinical-pathologists-and-the-jewish-consumptives-relief-society
#17
James R Wright, Jeanne Abrams
CONTEXT: - In the early 20th century, the future of hospital-based clinical pathology practice was uncertain and this situation led to the formation of the American Society for Clinical Pathologists in 1922. Philip Hillkowitz and Ward Burdick were its cofounders. No biography of Hillkowitz exists. OBJECTIVE: - To explore the life, beliefs, and accomplishments of Philip Hillkowitz. DESIGN: - Available primary and secondary historical sources were reviewed...
October 13, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29024951/bans-of-who-class-i-pesticides-in-bangladesh-suicide-prevention-without-hampering-agricultural-output
#18
Fazle Rabbi Chowdhury, Gourab Dewan, Vasundhara R Verma, Duleeka W Knipe, Ishrat Tahsin Isha, M Abul Faiz, David J Gunnell, Michael Eddleston
Background: Pesticide self-poisoning is a major problem in Bangladesh. Over the past 20-years, the Bangladesh government has introduced pesticide legislation and banned highly hazardous pesticides (HHPs) from agricultural use. We aimed to assess the impacts of pesticide bans on suicide and on agricultural production. Methods: We obtained data on unnatural deaths from the Statistics Division of Bangladesh Police, and used negative binomial regression to quantify changes in pesticide suicides and unnatural deaths following removal of WHO Class I toxicity HHPs from agriculture in 2000...
August 18, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28940348/empty-spaces
#19
Adira Hulkower
"I'm Jewish, you know, and my mother said, 'Always trust the rabbis.'" I never heard Mr. Weisman's refrain from his own lips. I never heard him say any words all. By the time I met him he was in a vegetative state, a man on the precipice of invisibility-white hair, thin pale limbs, melting into sheets of the same color. When I think about Mr. Weisman, I see empty spaces-the absence of his voice, the too-large bed for his shrinking frame, the always-empty chair by his bedside, and most of all, the myriad gaps in his life story...
September 2017: Hastings Center Report
https://www.readbyqxmd.com/read/28927400/genome-sequencing-of-the-staple-food-crop-white-guinea-yam-enables-the-development-of-a-molecular-marker-for-sex-determination
#20
Muluneh Tamiru, Satoshi Natsume, Hiroki Takagi, Benjamen White, Hiroki Yaegashi, Motoki Shimizu, Kentaro Yoshida, Aiko Uemura, Kaori Oikawa, Akira Abe, Naoya Urasaki, Hideo Matsumura, Pachakkil Babil, Shinsuke Yamanaka, Ryo Matsumoto, Satoru Muranaka, Gezahegn Girma, Antonio Lopez-Montes, Melaku Gedil, Ranjana Bhattacharjee, Michael Abberton, P Lava Kumar, Ismail Rabbi, Mai Tsujimura, Toru Terachi, Wilfried Haerty, Manuel Corpas, Sophien Kamoun, Günter Kahl, Hiroko Takagi, Robert Asiedu, Ryohei Terauchi
BACKGROUND: Root and tuber crops are a major food source in tropical Africa. Among these crops are several species in the monocotyledonous genus Dioscorea collectively known as yam, a staple tuber crop that contributes enormously to the subsistence and socio-cultural lives of millions of people, principally in West and Central Africa. Yam cultivation is constrained by several factors, and yam can be considered a neglected "orphan" crop that would benefit from crop improvement efforts...
September 19, 2017: BMC Biology
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