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https://www.readbyqxmd.com/read/29344753/comparative-approach-of-mri-based-brain-tumor-segmentation-and-classification-using-genetic-algorithm
#1
Nilesh Bhaskarrao Bahadure, Arun Kumar Ray, Har Pal Thethi
The detection of a brain tumor and its classification from modern imaging modalities is a primary concern, but a time-consuming and tedious work was performed by radiologists or clinical supervisors. The accuracy of detection and classification of tumor stages performed by radiologists is depended on their experience only, so the computer-aided technology is very important to aid with the diagnosis accuracy. In this study, to improve the performance of tumor detection, we investigated comparative approach of different segmentation techniques and selected the best one by comparing their segmentation score...
January 17, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29338082/racial-ethnic-differences-in-thyroid-cancer-incidence-in-the-united-states-2007-2014
#2
Kristin S Weeks, Amanda R Kahl, Charles F Lynch, Mary E Charlton
BACKGROUND: Small tumor diagnostic tools including ultrasound-guided fine needle aspiration (FNA) and computed tomography (CT) could be causing rising and racially/ethnically different thyroid cancer incidence rates due to variable overdiagnosis of indolent tumors. Papillary tumors and <40 mm tumors are most likely to be overdiagnosed as indolent tumors by FNA and CT. METHODS: Age-adjusted incidence rates (AAIRs) for the years 2007-2014 were calculated for race/ethnicity (white, Hispanic, Asian, African American, Native American) by patient/tumor characteristics for microscopically confirmed malignant thyroid cancer cases in the Surveillance, Epidemiology, and End Results Program 18 database (SEER 18; N = 93,607)...
January 16, 2018: Cancer
https://www.readbyqxmd.com/read/29327314/computational-modeling-for-cardiac-resynchronization-therapy
#3
Angela W C Lee, Caroline Mendonca Costa, Marina Strocchi, Christopher A Rinaldi, Steven A Niederer
Cardiac resynchronization therapy (CRT) is an effective treatment for heart failure (HF) patients with an electrical substrate pathology causing ventricular dyssynchrony. However 40-50% of patients do not respond to treatment. Cardiac modeling of the electrophysiology, electromechanics, and hemodynamics of the heart has been used to study mechanisms behind HF pathology and CRT response. Recently, multi-scale dyssynchronous HF models have been used to study optimal device settings and optimal lead locations, investigate the underlying cardiac pathophysiology, as well as investigate emerging technologies proposed to treat cardiac dyssynchrony...
January 11, 2018: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/29325342/-computer-aided-diagnosis-system-of-breast-ultrasound-based-on-support-vector-machine-a-clinical-analysis
#4
Z W Chen, H M Wang, J B Wu, X Y Wang, M Lin, Y Lin, H H Zhang, B J Ten, X X Huang
Objective: To investigate the value of based on support vector machine (SVM) breast ultrasonography technology of Computer-Assisted diagnosis (CAD) for differential diagnosis of benign and malignant breast masses. Methods: Total of 143 patients who had 151 breast masses were collected in Fujian Maternity and Children Health Hospital or The Fist Affiliated Hospital of Fujian Medical University from June 2014 to December 2015. Based on pathological results as the gold standard, the diagnostic efficiency of CAD and ultrasonography were compared...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29324373/abdominal-ct-aided-diagnosis-of-acute-appendicitis-in-the-presence-of-mobile-cecum-a-case-report
#5
Kentaro Yazawa, Yuki Azuma, Tomohiro Kurokawa, Yuichiro Yoshioka, Giichiro Tsurita, Masaru Shinozaki
INTRODUCTION: A mobile cecum is a frequently encountered congenital anomaly. It is important to recognize this atypical position of the cecum as it may interfere with an accurate diagnosis of acute appendicitis. PRESENTATION OF CASE: A 48-year-old man presented with abdominal pain, anorexia, and fever. He had mild lower abdominal discomfort, and rebound tenderness in the suprapubic region, but no guarding or right lower quadrant findings. Laboratory tests identified an elevated white blood cell count (12350 cells/mL) and C-reactive protein level (4...
December 28, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29318397/a-computer-aided-decision-support-system-for-detection-and-localization-of-cutaneous-vasculature-in-dermoscopy-images-via-deep-feature-learning
#6
Pegah Kharazmi, Jiannan Zheng, Harvey Lui, Z Jane Wang, Tim K Lee
Vascular structures of skin are important biomarkers in diagnosis and assessment of cutaneous conditions. Presence and distribution of lesional vessels are associated with specific abnormalities. Therefore, detection and localization of cutaneous vessels provide critical information towards diagnosis and stage status of diseases. However, cutaneous vessels are highly variable in shape, size, color and architecture, which complicate the detection task. Considering the large variability of these structures, conventional vessel detection techniques lack the generalizability to detect different vessel types and require separate algorithms to be designed for each type...
January 9, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29316947/diagnostic-utility-of-ct-in-differentiating-between-ruptured-ovarian-corpus-luteal-cyst-and-ruptured-ectopic-pregnancy-with-hemorrhage
#7
Xiaohong Liu, Litao Song, Jian Wang, Qin Liu, Yingna Liu, Xin Zhang
BACKGROUND: To evaluate the performance of computed tomography (CT) as a diagnostic aid to differentiate between ruptured ovarian corpus luteal cyst (ROCLC) and ruptured ectopic pregnancy with hemorrhage (REPWH). METHODS: A total of 36 patients treated at our hospitals for ROCLC and REPWH from June 2014 to August 2017 were included in this study. Based on the diagnosis, the study population was divided into ROCLC group (n = 21) and REPWH group (n = 15). CT scans were performed for all patients prior to treatment...
January 9, 2018: Journal of Ovarian Research
https://www.readbyqxmd.com/read/29311420/computer-aided-diagnosis-of-lung-cancer-the-effect-of-training-datasets-on-classification-accuracy-of-lung-nodules
#8
Jing Gong, Ji-Yu Liu, Xi-Wen Sun, Bin Zheng, Sheng-Dong Nie
This study aims to develop a computer-aided diagnosis (CADx) scheme for classification between malignant and benign lung nodules, and also assess whether CADx performance changes in detecting nodules associated with early and advanced stage lung cancer. Methods: The study involves 243 biopsy-confirmed pulmonary nodules. Among them, 76 are benign, 81 are stage I and 86 are stage III malignant nodules. Cases are partitioned into 3 datasets involving: (1) all nodules, (2) benign and stage I malignant nodules, and (3) benign and stage III malignant nodules...
January 9, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29304847/identification-of-the-pericardiacophrenic-vein-on-ct
#9
Yoshiyuki Ozawa, Ritsuko Suzuki, Masaki Hara, Yuta Shibamoto
BACKGROUND: To evaluate the depictability of pericardiacophrenic veins (PCPV) as landmarks for the location of the phrenic nerves on multi-detector-row computed tomography (MDCT), and to investigate the usefulness of depicting the PCPV to aid differential diagnosis of anterior mediastinal lesions. METHODS: Fifty-six patients with anterior mediastinal lesions (Fifty lesions originated from the thymus, six were of non-thymic origin) were evaluated. Contrast-enhanced CT scans of the chest were performed in all cases before diagnosis, and 22 of these scans were performed with electrocardiographic (ECG) gating...
January 5, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29299826/differentiation-of-antemortem-pulmonary-thromboembolism-and-postmortem-clot-with-unenhanced-mri-a-case-report
#10
Ingo von Both, Silvio Giancarlo Bruni, Jayantha C Herath
We report a case of a 39-year-old woman who died of fulminant pulmonary thromboembolism (PE). Autopsy showed classical findings of fulminant PE with occlusion of the bilateral main stem pulmonary arteries. Ancillary testing revealed inherited thrombophilia (Prothrombin 20,210 G > A and MTHFR 677 C > T mutation). Pre-autopsy postmortem computed tomography was used to test whether virtual imaging studies alone (virtual autopsy) would be sufficient to detect PE. Our studies show that computed tomography (CT) can differentiate antemortem clots from a postmortem clot in certain cases, particularly when combined with magnetic resonance imaging (MRI), which is superior in the assessment of soft tissue...
January 4, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29291389/digital-diagnosis-and-treatment-program-for-maxillofacial-fractures-a-retrospective-analysis-of-626-cases
#11
Wei Zeng, Xiaotian Lian, Gang Chen, Rui Ju, Weidong Tian, Wei Tang
PURPOSE: The purpose of this study was to evaluate the accuracy of the digital diagnosis and treatment program for maxillofacial fractures. MATERIALS AND METHODS: The data of 626 patients with maxillofacial fractures were analyzed retrospectively from January 2010 to August 2016. These patients were divided into 2 groups. In the experimental group, preoperative planning was conducted and transferred to patients with guiding templates and navigation according to the digital diagnosis and treatment program for maxillofacial fractures...
December 9, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29291200/human-herpesvirus-8-positive-iatrogenic-kaposi-s-sarcoma-in-the-setting-of-refractory-ulcerative-colitis
#12
Erica Duh, Sean Fine
Although Kaposi sarcoma (KS) has been more traditionally considered an AIDS-defining illness, it may also be seen in individuals on immunosuppresive therapy. We report a case of a patient who presented to the hospital in the setting of increasingly refractory ulcerative colitis. Computed tomography scan of the abdomen was consistent with sigmoid diverticulititis and blood cultures were positive for Klebsiella. After a course of antibiotics with resolution of infection, a colonoscopy was performed to evaluate his diverticulitis and incidentally revealed a new rectal tumor...
December 16, 2017: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/29290509/ambient-mass-spectrometry-for-rapid-diagnosis-of-psychoactive-drugs-overdose-in-an-unstable-patient
#13
Chi-Wei Lee, Yu-Ying Chao, Jentaie Shiea, Jheng-Heng Shen, Hei-Hwa Lee, Bai-Hsiun Chen
A 25-year-old man suffered from consciousness change was sent to our emergency department by friends who reported that they were not sure what had happened to him. Physical examination revealed bilateral pupils dilatation, lethargy, slurred speech, and ataxia. Computer-aided tomographic scan of the brain revealed no definite evidence of intracranial lesions. Routine laboratory tests revealed total physiological turmoil. Despite immediate commencement of aggressive treatment, the patient's condition deteriorated long before the traditional drug screen provided an answer for the identities of the multiple drugs overdose...
December 20, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29290048/screening-and-detection-of-delirium-in-older-ed-patients-performance-of-the-modified-confusion-assessment-method-for-the-emergency-department-mcam-ed-a-two-step-tool
#14
Wolfgang Hasemann, Florian F Grossmann, Rahel Stadler, Roland Bingisser, Dieter Breil, Martina Hafner, Reto W Kressig, Christian H Nickel
Delirium is frequent in older Emergency Department (ED) patients, but detection rates for delirium in the ED are low. To aid in identifying delirium, we developed and implemented a two-step systematic delirium screening and assessment tool in our ED: the modified Confusion Assessment Method for the Emergency Department (mCAM-ED). Components of the mCAM-ED include: (1) screening for inattention, the main feature of delirium, which was performed with the Months Backwards Test (MBT); (2) delirium assessment based on a structured interview with questions from the Mental Status Questionnaire by Kahn et al...
December 30, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29286609/lung-lesion-detection-in-ct-scan-images-using-the-fuzzy-local-information-cluster-means-flicm-automatic-segmentation-algorithm-and-back-propagation-network-classification
#15
M Lavanya, P Muthu Kannan
Lung cancer is a frequently lethal disease often causing death of human beings at an early age because of uncontrolled cell growth in the lung tissues. The diagnostic methods available are less than effective for detection of cancer. Therefore an automatic lesion segmentation method with computed tomography (CT) scans has been developed. However it is very difficult to perform automatic identification and segmentation of lung tumours with good accuracy because of the existence of variation in lesions. This paper describes the application of a robust lesion detection and segmentation technique to segment every individual cell from pathological images to extract the essential features...
December 29, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/29286180/computer-aided-system-for-diagnosing-thyroid-nodules-on-ultrasound-a-comparison-with-radiologist-based-clinical-assessments
#16
Luying Gao, Ruyu Liu, Yuxin Jiang, Wenfeng Song, Ying Wang, Jia Liu, Juanjuan Wang, Dongqian Wu, Shuai Li, Aimin Hao, Bo Zhang
BACKGROUND: The purpose of this study was to compare the diagnostic efficiency of a thyroid ultrasound computer-aided diagnosis (CAD) system with that of 1 radiologist. METHODS: This study retrospectively reviewed 342 surgically resected thyroid nodules from July 2013 to December 2013 at our center. The nodules were assessed on typical ultrasound images using the CAD system and reviewed by 1 experienced radiologist. The radiologist stratified the risk of malignancy using the Thyroid Imaging Reporting and Data Systems (TIRADS) and the American Thyroid Association (ATA) guidelines...
December 29, 2017: Head & Neck
https://www.readbyqxmd.com/read/29284926/a-clinicopathological-study-of-various-oral-cancer-diagnostic-techniques
#17
REVIEW
G Ulaganathan, K Thanvir Mohamed Niazi, Soundarya Srinivasan, V R Balaji, D Manikandan, K A Shahul Hameed, A Banumathi
Oral cancer is one of the most commonly occurring malignant tumors in the head and neck regions with high incident rate and mortality rate in the developed countries than in the developing countries. Generally, the survival rate of cancer patients may increase when diagnosed at early stage, followed by prompt treatment and therapy. Recently, cancer diagnosis and therapy design for a specific cancer patient have been performed with the advanced computer-aided techniques. The responses of the cancer therapy could be continuously monitored to ensure the effectiveness of the treatment process that hardly requires diagnostic result as quick as possible to improve the quality and patient care...
November 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29279165/computer-aided-diagnosis-of-contrast-enhanced-spectral-mammography-a-feasibility-study
#18
Bhavika K Patel, Sara Ranjbar, Teresa Wu, Barbara A Pockaj, Jing Li, Nan Zhang, Mark Lobbes, Bin Zhang, J Ross Mitchell
OBJECTIVE: To evaluate whether the use of a computer-aided diagnosis-contrast-enhanced spectral mammography (CAD-CESM) tool can further increase the diagnostic performance of CESM compared with that of experienced radiologists. MATERIALS AND METHODS: This IRB-approved retrospective study analyzed 50 lesions described on CESM from August 2014 to December 2015. Histopathologic analyses, used as the criterion standard, revealed 24 benign and 26 malignant lesions. An expert breast radiologist manually outlined lesion boundaries on the different views...
January 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29277009/label-free-sensor-for-automatic-identification-of-erythrocytes-using-digital-in-line-holographic-microscopy-and-machine-learning
#19
Taesik Go, Hyeokjun Byeon, Sang Joon Lee
Cell types of erythrocytes should be identified because they are closely related to their functionality and viability. Conventional methods for classifying erythrocytes are time consuming and labor intensive. Therefore, an automatic and accurate erythrocyte classification system is indispensable in healthcare and biomedical fields. In this study, we proposed a new label-free sensor for automatic identification of erythrocyte cell types using a digital in-line holographic microscopy (DIHM) combined with machine learning algorithms...
December 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29275487/extraction-selection-and-comparison-of-features-for-an-effective-automated-computer-aided-diagnosis-of-parkinson-s-disease-based-on-123i-fp-cit-spect-images
#20
Francisco P M Oliveira, Diogo Borges Faria, Durval C Costa, Miguel Castelo-Branco, João Manuel R S Tavares
PURPOSE: This work aimed to assess the potential of a set of features extracted from [123I]FP-CIT SPECT brain images to be used in the computer-aided "in vivo" confirmation of dopaminergic degeneration and therefore to assist clinical decision to diagnose Parkinson's disease. METHODS: Seven features were computed from each brain hemisphere: five standard features related to uptake ratios on the striatum and two features related to the estimated volume and length of the striatal region with normal uptake...
December 23, 2017: European Journal of Nuclear Medicine and Molecular Imaging
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