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Negative reciprocity

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https://www.readbyqxmd.com/read/29781659/nicotine-deprivation-increases-pain-intensity-neurogenic-inflammation-and-mechanical-hyperalgesia-among-daily-tobacco-smokers
#1
Joseph W Ditre, Emily L Zale, Lisa R LaRowe, Jesse D Kosiba, Martin J De Vita
An evolving reciprocal model posits that pain and tobacco smoking behavior interact in the manner of a positive feedback loop, resulting in greater pain and the maintenance of nicotine dependence. There is also reason to believe that abstaining from smoking may increase pain during the early stages of smoking cessation. The goal of this study was to test the effects of nicotine deprivation on experimental pain reactivity. Daily tobacco cigarette smokers (N = 165; 43% female) were randomized to either extended nicotine deprivation (12-24 hr smoking abstinence), minimal deprivation (2 hr smoking abstinence), or continued smoking conditions, prior to undergoing pain induction via topical capsaicin...
May 21, 2018: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/29777364/cell-division-and-turgor-mediate-enhanced-plant-growth-in-arabidopsis-plants-treated-with-the-bacterial-signalling-molecule-lumichrome
#2
Motlalepula Pholo, Beatrix Coetzee, Hans J Maree, Philip R Young, James R Lloyd, Jens Kossmann, Paul N Hills
Transcriptomic analysis indicates that the bacterial signalling molecule lumichrome enhances plant growth through a combination of enhanced cell division and cell enlargement, and possibly enhances photosynthesis. Lumichrome (7,8 dimethylalloxazine), a novel multitrophic signal molecule produced by Sinorhizobium meliloti bacteria, has previously been shown to elicit growth promotion in different plant species (Phillips et al. in Proc Natl Acad Sci USA 96:12275-12280, https://doi.org/10.1073/pnas.96.22.12275 , 1999)...
May 17, 2018: Planta
https://www.readbyqxmd.com/read/29772080/substance-p-and-calcitonin-gene-related-peptide-expression-in-human-periodontal-ligament-after-root-canal-preparation-with-reciproc-blue-waveone-gold-xp-endoshaper-and-hand-files
#3
J Caviedes-Bucheli, N Rios-Osorio, M Rey-Rojas, F Laguna-Rivero, M M Azuero-Holguin, L E Diaz, H Curtidor, J J Castaneda-Ramirez, H R Munoz
AIM: To quantify the Substance P (SP) and Calcitonin gene-related peptide (CGRP) expression in healthy human periodontal ligament from premolars after root canal preparation with Reciproc Blue, WaveOne Gold, XP EndoShaper and hand files. METHODOLOGY: Fifty human periodontal ligament samples were obtained from healthy mandibular premolars where extraction was indicated for orthodontic reasons. Prior to extraction, 40 of these premolars were equally divided into four groups, and root canals were prepared using four different systems: Reciproc Blue, WaveOne Gold, XP EndoShaper, and a hand instrumentation technique...
May 17, 2018: International Endodontic Journal
https://www.readbyqxmd.com/read/29769279/microbial-interactions-in-the-cystic-fibrosis-airway
#4
Ann M Granchelli, Frederick R Adler, Ruth H Keogh, Christiana Kartsonaki, David R Cox, Theodore G Liou
Interactions in the airway ecology of cystic fibrosis may alter organism persistence and clinical outcomes. Better understanding of such interactions could guide clinical decisions. We fitted logistic regression models using generalized estimating equations to longitudinal two-year patient cohorts in the Cystic Fibrosis Foundation Patient Registry, 2003-2011 to study associations between airway organisms present in each calendar year and their presence in the subsequent year. Models were adjusted for clinical characteristics and multiple observations per patient and tested for sensitivity to cystic fibrosis-specific treatments...
May 16, 2018: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/29769265/reciprocal-negative-regulation-between-lmx1a-and-lmo4-is-required-for-inner-ear-formation
#5
Yanhan Huang, Jennifer Hill, Andrew Yatteau, Loksum Wong, Tao Jiang, Jelena Petrovic, Lin Gan, Lijin Dong, Doris K Wu
LIM-domain containing transcription factors (LIM-TFs) are conserved factors important for embryogenesis. The specificity of these factors in transcriptional regulation is conferred by the complexes they form with other proteins such as LIM-domain-binding (Ldb) proteins and LIM-domain only (LMO) proteins. Unlike LIM-TF, these proteins do not bind DNA directly. LMO are negative regulators of LIM-TF and they function by competing with LIM-TFs for binding to Ldbs. Although the LIM-TF Lmx1a is expressed in the developing mouse hindbrain, which provides many of the extrinsic signals for inner ear formation, conditional knockout embryos of both sexes show that the inner ear source of Lmx1a is the major contributor of ear patterning...
May 16, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29768108/gender-differences-in-the-effect-of-social-resources-and-social-status-on-the-retirement-satisfaction-and-health-of-retirees
#6
Yihan Wang, Christina Matz-Costa
This study explores the effect of positive and negative social support, social reciprocity, and subjective social status on the retirement satisfaction and health of retirees and gender differences therein. Using cross-sectional data from the 2010 and 2012 waves of the Health and Retirement Study (HRS), we found that social support seems to matter more for the retirement satisfaction and health of women, while social reciprocity matters more for the health of men and subjective social status for the retirement satisfaction of men...
May 16, 2018: Journal of Gerontological Social Work
https://www.readbyqxmd.com/read/29767533/sirt1-controls-poly-i-c-dependent-mmp9-activation-in-primary-human-nasal-epithelial-cells
#7
Masanobu Suzuki, Mahnaz Ramezanpour, Clare Cooksley, Jian Li, Yuji Nakamaru, Akihiro Homma, Alkis Psaltis, Peter-John Wormald, Sarah Vreugde
BACKGROUND: Matrix metalloproteinase 9 (MMP9) is thought to be involved in the etiopathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and cleaves collagen IV causing hyperpermeability of the basement membrane within mucosal tissue. It is known that MMP9 expression is negatively affected by sirtuin-1 (SIRT-1) in human monocytotic cells, retinal endothelial cells and epithelial carcinoma cells. However, it is unknown which factors affect MMP9 expression and activity in human nasal epithelial cells (HNECs)...
May 16, 2018: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/29764607/the-impact-of-loneliness-and-relationship-quality-on-life-satisfaction-a-longitudinal-dyadic-analysis-in-persons-with-physical-disabilities-and-their-partners
#8
Hannah Tough, Martin W G Brinkhof, Johannes Siegrist, Christine Fekete
OBJECTIVE: Persons with physical disabilities and their caregiving partners are at an increased risk of experiencing reduced life satisfaction. One potential explanation for this trend may be the potentially harmful effects of loneliness and poor relationship quality which this population often experience. To date, little is known about how the perceptions of loneliness and relationship quality affect life satisfaction in the disability and caregiving setting, furthermore the directionality of effect is not well understood...
July 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29757077/investigating-whether-maternal-memory-specificity-is-indirectly-associated-with-child-memory-specificity-through-maternal-reminiscing
#9
Laura Jobson, Kimberly Burford, Breana Burns, Amelia Baldry, Yun Wu
Maternal reminiscing and remembering has a profound influence on the development of children's autobiographical remembering skills. The current study investigated the relationships between maternal memory specificity, maternal reminiscing and child memory specificity. Participants consisted of 40 mother-child dyads. Children's age ranged between 3.5 and 6 years. Mothers and children participated in individual assessments of autobiographical memory specificity. Dyads participated in a joint reminiscing task about three past emotional (happy, sad, stressful) events...
May 14, 2018: Memory
https://www.readbyqxmd.com/read/29755379/behavioral-patterns-of-children-involved-in-bullying-episodes
#10
Carlos V Santoyo, Brenda G Mendoza
This study applied a systematic observation strategy to identify coercive behavioral patterns in school environments. The aim was to describe stability and change in the behavioral patterns of children identified as victims of bullying. To this end, the following specific objectives were defined: (1) to identify episodes of bullying based on the frequency of negative behaviors received and power imbalances between bully and victim; (2) to describe stability and behavioral changes in student victims based on their social and academic conduct and the aggression they receive from peers and teachers; and (3) to describe the functional mechanisms responsible for the process of social organization (i...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29754579/peer-relationships-and-quality-of-life-in-11-12-year-old-children-the-health-oriented-pedagogical-project-hopp
#11
Natalia Lezhnieva, Per Morten Fredriksen, Mona Bekkhus
AIMS: Social interactions play an important role in our everyday life. Studies on children's quality of life (QoL) show that peer relations are associated with both positive and negative outcomes. Popularity defines the degree to which a child is liked by his or her peers, whereas reciprocal friendship occurs when two children mutually nominate each other as friends. The overall aim was to examine associations between peer relations and children's QoL. METHODS: Baseline data were from the Health Oriented Pedagogical Project (HOPP)...
May 2018: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29749452/mef2%C3%A2-activated-long-non%C3%A2-coding-rna-pcgem1-promotes-cell-proliferation-in-hormone%C3%A2-refractory-prostate-cancer-through-downregulation-of-mir%C3%A2-148a
#12
Shibao Zhang, Zongwu Li, Longyang Zhang, Zhonghua Xu
Prostate cancer gene expression marker 1 (PCGEM1) is a prostate‑specific gene overexpressed in prostate cancer cells that promotes cell proliferation. To study the molecular mechanism of PCGEM1 function in hormone‑refractory prostate cancer, the interaction between myocyte enhancer factor 2 (MEF2) and PCGEM1 was assessed by a luciferase reporter assay and chromatin immunoprecipitation (ChIP) assay. In addition, the underlying mechanism of PCGEM1 regulating expression of microRNA (miR)‑148a in PC3 prostate cancer cells was evaluated...
May 4, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29740543/quorum-sensing-signaling-and-quenching-in-the-multidrug-resistant-pathogen-stenotrophomonas-maltophilia
#13
REVIEW
Pol Huedo, Xavier Coves, Xavier Daura, Isidre Gibert, Daniel Yero
Stenotrophomonas maltophilia is an opportunistic Gram-negative pathogen with increasing incidence in clinical settings. The most critical aspect of S. maltophilia is its frequent resistance to a majority of the antibiotics of clinical use. Quorum Sensing (QS) systems coordinate bacterial populations and act as major regulatory mechanisms of pathogenesis in both pure cultures and poly-microbial communities. Disruption of QS systems, a phenomenon known as Quorum Quenching (QQ), represents a new promising paradigm for the design of novel antimicrobial strategies...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29740358/the-comorbidity-between-internet-gaming-disorder-and-depression-interrelationship-and-neural-mechanisms
#14
Lu Liu, Yuan-Wei Yao, Chiang-Shan R Li, Jin-Tao Zhang, Cui-Cui Xia, Jing Lan, Shan-Shan Ma, Nan Zhou, Xiao-Yi Fang
Internet gaming disorder (IGD) is characterized by cognitive and emotional deficits. Previous studies have reported the co-occurrence of IGD and depression. However, extant brain imaging research has largely focused on cognitive deficits in IGD. Few studies have addressed the comorbidity between IGD and depression symptoms and underlying neural mechanisms. Here, we systematically investigated this issue by combining a longitudinal survey study, a cross-sectional resting-state functional connectivity (rsFC) study and an intervention study...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29730313/exploring-detection-of-contact-vs-fantasy-online-sexual-offenders-in-chats-with-minors-statistical-discourse-analysis-of-self-disclosure-and-emotion-words
#15
Ming Ming Chiu, Kathryn C Seigfried-Spellar, Tatiana R Ringenberg
This exploratory study is the first to identify content differences between youths' online chats with contact child sex offenders (CCSOs; seek to meet with youths) and those with fantasy child sex offenders (FCSOs; do not meet with youths) using statistical discourse analysis (SDA). Past studies suggest that CCSOs share their experiences and emotions with targeted youths (self-disclosure grooming tactic) and encourage them to reciprocate, to build trust and closer relationships through a cycle of self-disclosures...
May 3, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29719261/negative-feedback-phosphorylation-of-g%C3%AE-subunit-ste18-and-the-ste5-scaffold-synergistically-regulates-mapk-activation-in-yeast
#16
Shilpa Choudhury, Parastoo Baradaran-Mashinchi, Matthew P Torres
Heterotrimeric G proteins (Gαβγ) are essential transducers in G protein signaling systems in all eukaryotes. In yeast, G protein signaling differentially activates mitogen-activated protein kinases (MAPKs)-Fus3 and Kss1-a phenomenon controlled by plasma membrane (PM) association of the scaffold protein Ste5. Here, we show that phosphorylation of the yeast Gγ subunit (Ste18), together with Fus3 docking on Ste5, controls the rate and stability of Ste5/PM association. Disruption of either element alone by point mutation has mild but reciprocal effects on MAPK activation...
May 1, 2018: Cell Reports
https://www.readbyqxmd.com/read/29717537/crosstalk-between-phosphorylation-and-o-glcnacylation-friend-or-foe
#17
REVIEW
Saar A M van der Laarse, Aneika C Leney, Albert J R Heck
A wide variety of protein post-translational modifications (PTMs) decorate cellular proteins, regulating their structure, interactions and ultimately their function. The density of co-occurring PTMs on proteins can be very high, where multiple PTMs can positively or negatively influence each others actions, nowadays termed PTM crosstalk. In this review we highlight recent progress in the area of PTM crosstalk, whereby we focus on crosstalk between protein phosphorylation and O-GlcNAcylation. These two PTMs largely target identical (i...
May 2, 2018: FEBS Journal
https://www.readbyqxmd.com/read/29710715/targeting-insulin-for-alzheimer-s-disease-mechanisms-status-and-potential-directions
#18
Jung Hyun Lee, Jordan B Jahrling, Larry Denner, Kelly T Dineley
Insulin resistance can occur when the body is unable to respond to insulin even in excess. In the brain, insulin manages glucose metabolism in regions such as the hippocampus and plays a key role in directly regulating ERK, a kinase required for the type of memory compromised in early Alzheimer's disease (AD). Human imaging studies show that brain glucose utilization declines with age and is notably impaired in subjects with early AD. Likewise, animal models of AD or insulin resistance, or both, demonstrate that dysfunctional insulin signaling and insulin resistance in the brain have reciprocity with neuroinflammation and aberrant accumulation of amyloid-β (Aβ), pathological hallmarks in AD...
April 27, 2018: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/29707011/bacterial-reduction-after-gutta-percha-removal-with-single-vs-multiple-instrument-systems
#19
Felipe Xavier, Giselle Nevares, Luciana Gominho, Renata Rodrigues, Marcely Cassimiro, Kaline Romeiro, Diana Albuquerque
Introduction: The aim of this study was to evaluate the effectiveness of a reciprocating single-instrument system (Reciproc-REC) compared with combined continuously rotating multiple-instrument systems [D-Race (DR) and BioRace (BR)] in reducing Enterococcus faecalis (E.f.) after gutta-percha removal. Methods and Materials: Forty-six extracted human maxillary incisors were prepared and contaminated with E.f. strain (ATCC 29212) for 30 days. The samples were obturated and randomly divided into two experimental groups for gutta-percha removal ( n =23): a REC group (R50) and a DR/BR group (DR1, DR2 and BR6)...
2018: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/29705784/coexisting-heart-failure-and-chronic-obstructive-pulmonary-disease-report-of-two-cases-treated-with-indacaterol-glycopyrronium
#20
Eugenio Roberto Cosentino, Daniela Degli Esposti, Rinaldo Miceli, Crescenzio Bentivenga, Matteo Landolfo, Ilaria Ricci Iamino, Luca Spinardi, Gianluigi Magri, Claudio Borghi
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide, and it is associated with a high economic burden. Heart failure shares some general symptoms with COPD; thus, diagnosing COPD is difficult in subjects with a history of heart failure, and spi-rometry is mandatory for confirmation. Moreover, COPD is a highly prevalent comorbidity negatively impacting the outcome of heart failure patients. We document here the treatment with indacaterol/glycopyrronium in 2 patients with concomitant COPD and heart failure...
2018: Respiration; International Review of Thoracic Diseases
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