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https://www.readbyqxmd.com/read/28426356/focus-group-findings-of-smoking-onset-among-male-youth-in-china
#1
Vivian C Sheer, Chang Molly Mao, Yi-Ru Regina Chen
BACKGROUND: Adolescence is associated with smoking initiation among men in China. The lack of qualitative studies using Chinese adolescent samples can pose challenges to enacting effective smoking prevention messages that resonate with male Chinese teenagers' thoughts, needs, and wishes. OBJECTIVE: This focus group study was designed to obtain in-depth contextual information on early smoking among male teenagers in China. METHODS: Twenty focus groups of 7-10 male students from vocational and junior colleges (N = 165) were conducted, approximately half in Shanxi and half in Guangdong...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28424658/%C3%AE-and-%C3%AE-2-adrenoceptor-control-of-vascular-tension-and-catecholamine-release-in-female-normotensive-and-spontaneously-hypertensive-rats
#2
Torill Berg
As in humans, young, female, spontaneously hypertensive rats (SHR) have a lower blood pressure than male SHR. In male, normotensive rats (WKY), α2- and β1+2-adrenoceptors (AR) reciprocally controlled catecholamine release and vascular smooth muscle tension. This interaction was malfunctioning in male SHR. The present study analyzed if a favorable shift in the α2/β1+2AR interaction may represent an antihypertensive protection in females. Female SHR (early hypertension, 12-14 weeks) and age-matched WKY were infused with tyramine (15 min) to stimulate norepinephrine (NE) release through the reuptake transporter, consequently preventing reuptake...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28420710/reciprocal-proteasome-mediated-degradation-of-pifs-and-hfr1-underlying-photomorphogenic-development-in-arabidopsis
#3
Xiaosa Xu, Praveen Kumar Kathare, Vinh Ngoc Pham, Qingyun Bu, Andrew Nguyen, Enamul Huq
The phytochrome-mediated regulation of photomorphogenesis under red and far-red light conditions involves both positive and negatively acting factors. The positively acting factors (e.g., HY5/HFR1/LAF1 and others) are degraded in the dark to prevent photomorphogenesis. By contrast, the negatively acting factors (e.g., PIFs) are degraded in response to light to promote photomorphogenesis. Here we show that the negatively acting factor, PIF1 is also degraded in the dark by direct heterodimerization with the positively acting factor, HFR1...
April 18, 2017: Development
https://www.readbyqxmd.com/read/28416735/reciprocal-control-of-lncrna-bcat1-and-%C3%AE-catenin-pathway-reveals-lncrna-bcat1-long-non-coding-rna-acts-as-a-tumor-suppressor-in-colorectal-cancer
#4
Fei Xie, Xudong Xiang, Qionglin Huang, Pengzhan Ran, Yuncang Yuan, Qian Li, Guoxiang Qi, Xiaopeng Guo, Chunjie Xiao, Shangyong Zheng
β-catenin plays a major role in tumor development and progression. The present study found that β-catenin was upregulated in 30 samples of colorectal cancer (CRC) tissue as compared to adjacent non-tumor tissues. Analysis of long non-coding RNA (lncRNA) expression profiles using the GSE18560 and GSE44097 datasets, which were generated via the Affymetrix plus 2.0 microarray platform and downloaded from the GEO database, revealed 20 differentially expressed lncRNAs following β-catenin knockdown. We focused on AK091631, a novel lncRNA, which we named lncRNA-β-catenin associated transcript 1 (LncRNA-BCAT1)...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28414471/the-reciprocal-dynamic-model-of-career-decision-ambiguity-tolerance-with-career-indecision-a-longitudinal-three-wave-investigation
#5
Hui Xu, Terence J G Tracey
The current study investigated the dynamic interplay of career decision ambiguity tolerance and career indecision over 3 assessment times in a sample of college students (n = 583). While the previous research has repeatedly shown an association of career decision ambiguity tolerance with career indecision, the direction of this association has not been adequately assessed with longitudinal investigation. It was hypothesized in this study that there is a reciprocal pattern of career decision ambiguity tolerance leading to subsequent career indecision and career indecision leading to subsequent career decision ambiguity tolerance...
April 17, 2017: Journal of Counseling Psychology
https://www.readbyqxmd.com/read/28407460/depressive-symptoms-and-their-interactions-with-emotions-and-personality-traits-over-time-interaction-networks-in-a-psychiatric-clinic
#6
Laura N Semino, Josef Marksteiner, Gernot Brauchle, Erik Danay
Objective: Associations between depression, personality traits, and emotions are complex and reciprocal. The aim of this study is to explore these interactions in dynamical networks and in a linear way over time depending on the severity of depression. Methods: Participants included 110 patients with depressive symptoms (DSM-5 criteria) who were recruited between October 2015 and February 2016 during their inpatient stay in a general psychiatric hospital in Hall in Tyrol, Austria...
April 13, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/28404930/microrna-regulation-of-progesterone-receptor-in-breast-cancer
#7
Avital Gilam, Ayelet Shai, Itamar Ashkenazi, Liat Appel Sarid, Assi Drobot, Amitai Bickel, Noam Shomron
Hormone receptor status is of significant value when deciding on anti-estrogenic adjuvant therapy for breast cancer tumors. However, while estrogen receptor (ER) regulation was intensively studied, the regulation of progesterone receptor (PR) levels has not been extensively investigated. MicroRNAs (miRNAs, miRs) are post-transcriptional negative regulators of gene expression involved in diverse cellular processes. The aim of this study was to identify miRNAs that regulate PR in breast cancer.We mapped potential miRNA binding sites for miR-181a, miR-23a and miR-26b on PR mRNA and demonstrated a direct regulation of PR by these three miRNAs by in-vitro Luciferase binding assays...
February 23, 2017: Oncotarget
https://www.readbyqxmd.com/read/28401989/cross-lagged-relations-between-teacher-and-parent-ratings-of-children-s-task-avoidance-and-different-literacy-skills
#8
George K Georgiou, Riikka Hirvonen, George Manolitsis, Jari-Erik Nurmi
BACKGROUND: Task avoidance is a significant predictor of literacy skills. However, it remains unclear whether the relation between the two is reciprocal and whether it is affected by the type of literacy outcome, who is rating children's task avoidance, and the children's gender. AIM: The purpose of this longitudinal study was to examine the cross-lagged relations between teacher and parent ratings of children's task avoidance and different literacy skills. SAMPLE: One hundred and seventy-two Greek children (91 girls, 81 boys) were followed from Grade 1 to Grade 3...
April 12, 2017: British Journal of Educational Psychology
https://www.readbyqxmd.com/read/28399463/distraction-or-cognitive-overload-using-modulations-of-the-autonomic-nervous-system-to-discriminate-the-possible-negative-effects-of-advanced-assistance-system
#9
D Ruscio, A J Bos, M R Ciceri
The interaction with Advanced Driver Assistance Systems has several positive implications for road safety, but also some potential downsides such as mental workload and automation complacency. Malleable attentional resources allocation theory describes two possible processes that can generate workload in interaction with advanced assisting devices. The purpose of the present study is to determine if specific analysis of the different modalities of autonomic control of nervous system can be used to discriminate different potential workload processes generated during assisted-driving tasks and automation complacency situations...
April 8, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28398134/-i-told-her-this-is-your-life-relationship-dynamics-partner-support-and-adherence-to-antiretroviral-therapy-among-south-african-couples
#10
Amy Conroy, Anna Leddy, Mallory Johnson, Thulani Ngubane, Heidi van Rooyen, Lynae Darbes
Despite the important role of social relationships for health and wellbeing, little is known about how primary partners affect adherence to HIV care and treatment. We qualitatively explored how relationship dynamics and partner support influence adherence among couples from KwaZulu-Natal, South Africa. Twenty-four heterosexual couples with at least one HIV-positive partner completed semi-structured interviews on topics including relationship dynamics (intimacy or emotional closeness, communication, violence), experiences with HIV care and treatment and HIV-related social support...
April 11, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28395529/mother-child-interactions-in-young-children-with-excessive-physical-aggression-and-in-typically-developing-young-children
#11
Nadine Urbain-Gauthier, Jaqueline Wendland
BACKGROUND: Among the multiple risk factors, the emergence of conduct problems in young children may be linked to harsh parenting and child's temperamental difficulties, leading to a reciprocal early discordant relationship. Little is known about the characteristics of early parent-child interactions in young children with physical aggression. OBJECTIVE: The purpose of the current study was to evaluate the characteristics of mother-child interactions in dyads referred for excessive physical aggression in young children under 5 years of age compared to mother-child interactions in typically developing young children...
April 1, 2017: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/28393199/smad4-deletion-in-blood-vessel-endothelial-cells-promotes-ovarian-cancer-metastasis
#12
Jie Yang, Ya Wang, Zhen Zeng, Long Qiao, Liang Zhuang, Qinglei Gao, Ding Ma, Xiaoyuan Huang
SMAD4 is a critical co-smad in signal transduction pathways activated in response to transforming growth factor-β (TGF-β)-related ligands, regulating cell growth and differentiation. The roles played by SMAD4 inactivation in tumors highlighted it as a tumor-suppressor gene. Herein, we report that loss of SMAD4 expression in vascular endothelial cells promotes ovarian cancer invasion. SiRNA transfer of this gene in the HUVEC reduced SMAD4 protein expression and function. Although it reduced the vessel endothelial cell tubule formation in vitro and in vivo, it did not affect the tumor growth significantly in vivo...
May 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28392406/environmental-enrichment-enhances-systems-level-consolidation-of-a-spatial-memory-after-lesions-of-the-ventral-midline-thalamus
#13
Mohamad Ali, Thibault Cholvin, Marc Antoine Muller, Brigitte Cosquer, Christian Kelche, Jean-Christophe Cassel, Anne Pereira de Vasconcelos
Lesions of the reuniens and rhomboid (ReRh) thalamic nuclei in rats do not alter spatial learning but shorten the period of memory persistence (Loureiro et al. 2012). Such persistence requires a hippocampo-cortical (prefrontal) dialog leading to memory consolidation at the systems level. Evidence for reciprocal connections with the hippocampus and the medial prefrontal cortex (mPFC) makes the ReRh a potential hub for regulating hippocampo-cortical interactions. As environmental enrichment (EE) fosters recovery of declarative-like memory functions after diencephalic lesions (e...
April 6, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28383074/phenotypic-and-genotypic-correlation-between-myopia-and-intelligence
#14
Katie M Williams, Pirro G Hysi, Ekaterina Yonova-Doing, Omar A Mahroo, Harold Snieder, Christopher J Hammond
Myopia, or near-sightedness, is our most common eye condition and the prevalence is increasing globally. Visual impairment will occur if uncorrected, whilst high myopia causes sight-threatening complications. Myopia is associated with higher intelligence. As both are heritable, we set out to examine whether there is a genetic correlation between myopia and intelligence in over 1,500 subjects (aged 14-18 years) from a twin birth cohort. The phenotypic correlation between refractive error and intelligence was -0...
April 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28376710/electrocardiographic-changes-mimicking-acute-coronary-syndrome-in-a-large-intracranial-tumour-a-diagnostic-dilemma
#15
Nilukshana Yogendranathan, H M M T B Herath, S P Pahalagamage, Aruna Kulatunga
BACKGROUND: ST elevation Myocardial infarction is a medical emergency. A variety of noncardiac conditions had been known to mimic the ECG changes that are seen in acute coronary syndrome. Although the common ECG changes that are documented with raised intracranial pressure are T inversions, prolongation of QT interval and sinus bradycardia, ST elevation or depression, arrhythmias and prominent U waves have also been recognized. However, ST elevations in association with primary intracranial tumours are rarely reported...
April 4, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28367131/infantile-anorexia-and-co-parenting-a-pilot-study-on-mother-father-child-triadic-interactions-during-feeding-and-play
#16
Loredana Lucarelli, Massimo Ammaniti, Alessio Porreca, Alessandra Simonelli
Infantile Anorexia (IA), defined by the Diagnostic Classification of Mental Health and Developmental Disorders of Infancy and Early Childhood Revised (DC: 0-3R, Zero To Three, 2005), occurs when the child (a) refuses to eat adequate amounts of food for at least 1 month, and shows growth deficiency, (b) does not communicate hunger and lacks interest in food, and (c) the child's food refusal does not follow a traumatic event and is not due to an underlying medical illness. IA usually emerges during the transition to self-feeding, when the child issues of autonomy are played out daily in the feeding situation...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28365469/the-impact-of-frailty-on-depressive-disorder-in-later-life-findings-from-the-netherlands-study-of-depression-in-older-persons
#17
R M Collard, M H L Arts, A H Schene, P Naarding, R C Oude Voshaar, H C Comijs
BACKGROUND: Physical frailty and depressive symptoms are reciprocally related in community-based studies, but its prognostic impact on depressive disorder remains unknown. METHODS: A cohort of 378 older persons (≥60 years) suffering from a depressive disorder (DSM-IV criteria) was reassessed at two-year follow-up. Depressive symptom severity was assessed every six months with the Inventory of Depressive Symptomatology, including a mood, motivational, and somatic subscale...
January 24, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28361752/an-empirically-derived-dietary-pattern-associated-with-breast-cancer-risk-is-validated-in-a-nested-case-control-cohort-from-a-randomized-primary-prevention-trial
#18
Brandon H Hidaka, Bruce F Kimler, Carol J Fabian, Susan E Carlson
BACKGROUND & AIMS: We reported an association between cytologic atypia, a reversible biomarker of breast cancer risk, and lower omega-3/omega-6 fatty acid ratio in blood and breast tissue. Our goal was to develop and validate a dietary pattern index in this high-risk sample of U.S. women, and test its capacity to predict incidence in a nested case-control cohort of Canadian women from a randomized trial of a low-fat dietary intervention for primary prevention of breast cancer. METHODS: Food intake was measured by food frequency questionnaire in the U...
February 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28360110/the-cftr-trafficking-mutation-f508del-inhibits-the-constitutive-activity-of-slc26a9
#19
Carol A Bertrand, Shalini Mitra, Sanjay K Mishra, Xiaohui Wang, Yu Zhao, Joseph M Pilewski, Dean R Madden, Raymond A Frizzell
Several members of the SLC26A family of anion transporters associate with CFTR, forming complexes in which CFTR and SLC26A functions are reciprocally regulated. This association is thought to be facilitated by PDZ scaffolding interactions. CFTR has been shown to be positively regulated by NHERF-1, and negatively regulated by CAL in airway epithelia. However, it's unclear which PDZ-domain protein(s) interact with SLC26A9, a SLC26A family member found in airway epithelia. We have previously shown that primary, human bronchial epithelia (HBE) from non-CF donors exhibit constitutive anion secretion attributable to SLC26A9...
March 30, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28337154/the-reciprocal-relationship-between-suicidality-and-stigma
#20
REVIEW
Bernardo Carpiniello, Federica Pinna
INTRODUCTION: Although suicidality is frequently the cause of stigma, it is conversely true that stigma may be the cause of suicidality. The present paper focuses on the complex relationships that exist between suicidal behavior and stigmatizing attitudes. METHODS: A narrative review of the topic will be presented on the basis of the relevant literature collected from an electronic search of PubMed, ISI Web of Knowledge, and Scopus databases, using stigma, public stigma, structural stigma, perceived stigma, self-stigma, suicide, attempted suicide, and suicidality as key words...
2017: Frontiers in Psychiatry
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