keyword
https://read.qxmd.com/read/38387871/diabetic-foot-screening-guidelines-and-the-role-of-artificial-intelligence-time-to-turn-the-tide
#21
REVIEW
Cynthia Formosa, Nachiappan Chockalingam, Nikolaos Papanas, Alfred Gatt
Despite medical and technological advancements, foot amputations continue to rise. Thus, the effort of diabetic foot management should be toward prevention and early diagnosis. Healthcare professionals need to be trained, equipped, and supported with adequate resources to be able to identify and deliver appropriate foot care. Every effort should be made to minimize the impact of complications and to ensure prompt access to care for everyone. Artificial intelligence and smart technology could provide a significant opportunity to improve efficiency in diabetes care, which may reduce diabetic foot complications...
February 22, 2024: International Journal of Lower Extremity Wounds
https://read.qxmd.com/read/38386520/assessment-of-diabetic-foot-ulcers-back-to-basics
#22
JOURNAL ARTICLE
Aby Mitchell, Barry Hill
Diabetic foot ulceration affects up to 34% of the global diabetic population as a result of poor glycaemic control. Complications resulting from diabetic foot ulceration can be complex, expensive and challenging. It is important for risk factors to be recognised early and for regular assessment to take place. Streamlining a coordinated approach that enhances communication and guides treatment approaches can help to improve wound outcomes.
February 22, 2024: British Journal of Nursing: BJN
https://read.qxmd.com/read/38379247/effect-of-a-multidisciplinary-team-approach-on-the-management-of-diabetic-foot-ulcers-on-the-central-coast-a-review-of-the-gosford-hospital-high-risk-foot-clinic
#23
REVIEW
Stephanie Mae Macfarlane, Sarina Xinyan Zhao, Jane Olivia Lafrenz, Manisha Vanya Nagaratnam, Adrian Tchen, Clare Elizabeth Linton, Lili Yuen
This retrospective cohort study aims to assess whether the implementation of a multidisciplinary approach in the Gosford Hospital High-Risk Foot Clinic improved outcomes of diabetic foot ulcers. Ulceration is a common foot complication of diabetes mellitus and greatly increases patient morbidity and mortality. Patients who attended at least one appointment at the Gosford Hospital High-Risk Foot Clinic in 2017 or 2019 were identified through the Gosford Hospital Podiatry department's records. The 2017 and 2019 cohorts were compared on measures of ulcer healing, incidence of amputation, incidence of vascular intervention and surgical debridement, percentage of patients admitted to hospital due to complications and use of systemic antibiotic therapy...
February 2024: International Wound Journal
https://read.qxmd.com/read/38379242/the-efficacy-and-safety-of-non-surgical-treatment-of-diabetic-foot-wound-infections-and-ulcers-a-systemic-review-and-meta-analysis
#24
JOURNAL ARTICLE
Xuchao Cai, Xin Fang, Linjun Wu, Xiaohu Meng
This meta-analysis evaluates the efficacy and safety of non-surgical treatments for diabetic foot ulcers and infections. After a rigorous literature review, seven studies were selected for detailed analysis. The findings demonstrate that non-surgical treatments significantly reduce wound infection rates (standardized mean difference [SMD] = -15.15, 95% confidence interval [CI]: [-19.05, -11.25], p < 0.01) compared to surgical methods. Ulcer healing rates were found to be comparable between non-surgical and surgical approaches (SMD = 0...
February 2024: International Wound Journal
https://read.qxmd.com/read/38377963/a-systematic-review-and-classification-of-factors-influencing-diabetic-foot-ulcer-treatment-adherence-in-accordance-with-the-who-dimensions-of-adherence-to-long-term-therapies
#25
JOURNAL ARTICLE
Gwyneth Wy Ng, Keith F Gan, Huiling Liew, Lixia Ge, Gary Ang, Joseph Molina, Yan Sun, Prajwala S Prakash, Keerthi B Harish, Zhiwen Joseph Lo
PURPOSE: Effective treatment of diabetic foot ulcers (DFUs) involves a multidisciplinary treatment plan to promote wound healing and prevent complications. Given the lack of consensus data on the factors affecting patient adherence, a systematic review was performed to identify and classify factors according to the WHO Dimensions of Adherence to Long-Term Therapies. METHODS: Six hundred and forty-three articles from PubMed, Embase, and Scopus were reviewed. The inclusion criteria included qualitative and quantitative studies which discussed factors affecting patient adherence to DFU treatment, had study populations that comprised patients with either prior history of or existing DFU, and had either prior history of DFU treatment or were currently receiving treatment...
February 20, 2024: International Journal of Lower Extremity Wounds
https://read.qxmd.com/read/38373396/studying-microbial-ecology-of-diabetic-foot-infections-significance-of-pcr-analysis-for-prudent-antimicrobial-stewardship
#26
JOURNAL ARTICLE
Deema Jaber, Nidal Younes, Enam Khalil, Abla Albsoul-Younes, Mohammed Zawiah, Amal G Al-Bakri
This study presents a comprehensive investigation into the microbial ecology of diabetic foot infections (DFIs), using molecular-polymerase chain reaction (PCR) analysis to accurately identify the causative agents. One hundred DFI patients were recruited and classified using the Depth Extent Phase and Associated Etiology (DEPA) score according to their severity. Results revealed polymicrobial infections in 75% of cases, predominantly featuring Staphylococcus epidermidis (83%) and Staphylococcus aureus (63%)...
February 19, 2024: International Journal of Lower Extremity Wounds
https://read.qxmd.com/read/38372560/diabetic-foot-ulcers-a-review-of-debridement-techniques
#27
JOURNAL ARTICLE
Brianna C Sa, Narges Maskan Bermudez, Stephanie V Shimon, Robert S Kirsner
Diabetic foot ulcers (DFUs) are a prevalent complication of diabetes mellitus (DM) and lead to significant morbidity and mortality. Patients with DM have a lifetime risk of DFUs as high as 34%. The pathogenesis of DFUs is multifactorial, and the most common underlying causes are poor glycemic control, peripheral neuropathy, peripheral vascular disease, foot deformity, and poor foot care. Diabetic lower-extremity complications are also a significant burden in terms of healthcare costs. In the United States alone, the direct cost of diabetic foot care has been estimated to be $8,659 per patient, with total annual medical costs for managing diabetic foot disease ranging from $9 to $13 billion...
February 15, 2024: Surgical Technology International
https://read.qxmd.com/read/38371116/antimicrobial-and-anti-biofilm-activities-of-coffea-arabica-l-against-the-clinical-strains-isolated-from-diabetic-foot-ulcers
#28
JOURNAL ARTICLE
Mohammad Zubair
Diabetes-related complications such as diabetic foot infections foster resilient biofilms, complicating treatment. Innovative therapeutic solutions are urgently needed to address this challenge. In this research, coffee bean powder (green coffee been powder [GCBP], roasted coffee bean powder [RCBP], and spent coffee powder ground [SCPG]) was extracted and assessed for its ability to impede biofilm formation and associated functions in extended-spectrum beta-lactamase (ESBL) and methicillin-resistant Staphylococcus aureus  (MRSA)-positive biofilm-forming strains of Pseudomonas aeruginosa (P...
January 2024: Curēus
https://read.qxmd.com/read/38371037/are-biodegradable-calcium-sulfate-antibiotic-beads-effective-and-safe-adjuvants-for-diabetic-foot-osteomyelitis
#29
JOURNAL ARTICLE
Talal Alkayali, Dominick Casciato, Jacob Wynes, Joel Chua, James B Doub
INTRODUCTION:  Diabetic foot osteomyelitis (DFO) is a highly morbid condition that commonly affects diabetic patients. Biodegradable calcium-sulfate antibiotic beads (CaSO4) are theoretical adjuvant agents to reduce morbidity in DFO. However, there is a paucity of research on the safety and effectiveness of CaSO4 beads in DFO. Therefore, the purpose of this study was to assess the safety and effectiveness of CaSO4 beads in different DFO locations. METHODS: We conducted a retrospective cohort study between January 1, 2015 and January 1, 2022 of patients with DFO who underwent surgical intervention and adjuvant CaSO4 beads placement...
January 2024: Curēus
https://read.qxmd.com/read/38363369/efficacy-of-acellular-fish-skin-graft-in-the-management-of-chronic-ulcer-a-systematic-review-and-meta-analysis
#30
JOURNAL ARTICLE
Jing Gao, Li-Xiu Ge, Qiao-Ying Gao, Ai-Min Zhang, Li-Juan Hu
BACKGROUND: The wounds failing to heal through a timely and orderly standard of care (SOC) treatment are considered as chronic wounds, which add significant burden to healthcare systems around the world. SOC treatment has been commonly applied for management of chronic wounds, but SOC alone may not be adequate to heal all ulcers effectively. Fish skin graft (FSG) is a xenogenic skin substitute which could be used for accelerating skin healing. The current study was performed with the view of evaluating the effectiveness of FSG as an adjuvant treatment of SOC for chronic ulcer treatment...
February 16, 2024: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/38356150/healing-of-diabetic-foot-ulcer-with-topical-and-oral-administrations-of-herbal-products-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#31
REVIEW
Mina Zamanifard, Morteza Nasiri, Fatemeh Yarahmadi, Sahar Zonoori, Omolbanin Razani, Zahra Salajegheh, Mohammad Imanipour, Seyed Mohammad Mohammadi, Nabi Jomehzadeh, Masoomeh Asadi
This systematic review aimed to qualitatively synthesize recent randomized controlled trials (RCTs) regarding the effect of topical application and oral intake of herbal products on the healing of diabetic foot ulcer (DFU). Also, we sought to pool the obtained findings in a meta-analysis using a random-effects model, if RCTs were relatively comparable and homogenous. A comprehensive search was performed on five electronic data sources from their inception through 23 January 2024. The RCTs, without restriction on the country of origin, were included if they compared the effect of administering standard treatments and/or placebo (i...
February 2024: International Wound Journal
https://read.qxmd.com/read/38354304/wound-bed-preparation-2024-delphi-consensus-on-foot-ulcer-management-in-resource-limited-settings
#32
JOURNAL ARTICLE
Hiske Smart, R Gary Sibbald, Laurie Goodman, Elizabeth A Ayello, Reneeka Jaimangal, John H Gregory, Sadanori Akita, Afsaneh Alavi, David G Armstrong, Helen Arputhanathan, Febe Bruwer, Jeremy Caul, Beverley Chan, Frans Cronje, Belen Dofitas, Jassin Hamed, Catherine Harley, Jolene Heil, Mary Hill, Devon Jahnke, Dale Kalina, Chaitanya Kodange, Bharat Kotru, Laura Lee Kozody, Stephan Landis, Kimberly LeBlanc, Mary MacDonald, Tobi Mark, Carlos Martin, Dieter Mayer, Christine Murphy, Harikrishna Nair, Cesar Orellana, Brian Ostrow, Douglas Queen, Patrick Rainville, Erin Rajhathy, Gregory Schultz, Ranjani Somayaji, Michael C Stacey, Gulnaz Tariq, Gregory Weir, Catharine Whiteside, Helen Yifter, Ramesh Zacharias
BACKGROUND: Chronic wound management in low-resource settings deserves special attention. Rural or under-resourced settings (ie, those with limited basic needs/healthcare supplies and inconsistent availability of interprofessional team members) may not be able to apply or duplicate best practices from urban or abundantly resourced settings. OBJECTIVE: The authors linked world expertise to develop a practical and scientifically sound application of the wound bed preparation model for communities without ideal resources...
February 13, 2024: Advances in Skin & Wound Care
https://read.qxmd.com/read/38350705/bartter-syndrome-like-phenotype-in-a-patient-with-type-2-diabetes-mellitus
#33
JOURNAL ARTICLE
Ravi Kumar, Nirmal Shreshta, Samir Samdarshi, Parikshit Chauhan
Bartter syndrome (BS) is a rare genetic tubulopathy affecting the loop of Henle leading to salt wasting. It is commonly seen in utero or in the early neonatal period. Rare cases of acquired BS are reported in association with infections like tuberculosis, granulomatous conditions like sarcoidosis, autoimmune diseases and drugs. The mainstay of management includes potassium, calcium and magnesium supplementation. We report the case of a woman in her 50s with a history of type 2 diabetes mellitus for the last 10 years, who presented with diabetic foot ulcers and generalised weakness with ECG changes suggestive of hypokalaemia...
February 13, 2024: BMJ Case Reports
https://read.qxmd.com/read/38327069/updated-scenario-on-negative-pressure-wound-therapy
#34
REVIEW
Harish Bhardwaj, Renjil Joshi, Anshita Gupta
Negative pressure wound therapy (NPWT) is a widely used and effective treatment for managing complex wounds. This document discusses how NPWT can be used in wound care in an updated way. The updated scenario on NPWT provides a concise overview of the current state of NPWT and its implications in clinical practice. It highlights recent developments in NPWT, as well as the advancements in this field. As part of NPWT, vacuum-assisted closure is used and negative pressure is applied to the wound bed. It discusses the key components and mechanisms...
February 7, 2024: International Journal of Lower Extremity Wounds
https://read.qxmd.com/read/38318295/modified-tibial-cortex-transverse-transport-for-diabetic-foot-ulcers-with-wagner-grade-%C3%A2-ii-a-study-of-98-patients
#35
JOURNAL ARTICLE
Junpeng Liu, Xingchen Yao, Ziyu Xu, Yue Wu, Fuchun Pei, Lin Zhang, Meng Li, Ming Shi, Xinru Du, Hui Zhao
BACKGROUND: Diabetic foot ulcers constitute a substantial healthcare burden on a global scale and present challenges in achieving healing. Our objective was to assess the efficacy of modified tibial cortex transverse transport surgery in managing refractory diabetic foot ulcers. METHODS: We retrospectively analyzed clinical data from 98 patients suffering from diabetic foot ulcers classified as Wagner grade ≥II who were admitted to our medical facility between January 2020 and June 2022...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38298002/effectiveness-of-stem-cell-therapy-for-diabetic-foot-ulcers-a-systematic-review-and-grade-compliant-bootstrapped-meta-analysis-of-randomized-clinical-trials
#36
JOURNAL ARTICLE
Shiv Kumar Mudgal, Subodh Kumar, Rakhi Gaur, Harminder Singh, Dibyajyoti Saikia, Saurabh Varshney, Pratima Gupta, Ashoo Grover, Seshadri Reddy Varikasuvu
Diabetic foot (DF) represents a severe complication of diabetes mellitus, imposing substantial psychological and economic burdens on affected individuals. This investigation sought to assess the therapeutic efficacy of stem cell interventions in the management of DF complications. A comprehensive systematic search across PubMed, Embase, CINAHL, Scopus, and the Cochrane library databases was conducted to identify pertinent studies for meta-analysis. Outcome measures encompassed ulcer or wound healing rates, amputation rates, angiogenesis, ankle-brachial index (ABI), and pain-free walking distance...
January 31, 2024: International Journal of Lower Extremity Wounds
https://read.qxmd.com/read/38295273/multifunctional-casein-based-wound-dressing-capable-of-monitoring-and-moderating-the-proteolytic-activity-of-chronic-wounds
#37
JOURNAL ARTICLE
Davood Kolahreez, Laleh Ghasemi-Mobarakeh, Felice Quartinello, Falk W Liebner, Georg M Guebitz, Doris Ribitsch
Every 1.2 s, a diabetic foot ulcer is developed, and every 20 s, one amputation is carried out in diabetic patients. Monitoring and controlling protease activity have been considered as a strategy for more efficient management of diabetic and other chronic wounds. This study aimed to develop a casein-based dressing that, by its disappearance, provides information about the activity of proteases and simultaneously harnesses proteolytic activity. Casein films were fabricated by using an aqueous solution, and heat treatment was successfully deployed as a green and clean approach to confer hydrolytic stability...
January 31, 2024: Biomacromolecules
https://read.qxmd.com/read/38292109/an-orthopedic-perspective-on-diabetic-foot-attack-a-case-report
#38
Aakaash Venkatesan, Chandan Noel, Waleed Akeel
INTRODUCTION: Diabetic foot attack (DFA), also known as diabetic foot ulceration, is a severe and potentially limb-threatening complication of diabetes mellitus. It refers to the development of open sores or ulcers on the feet of individuals with diabetes, often leading to infections, tissue damage, and, in extreme cases, amputation. The underlying cause of DFAs is multifactorial and involves a complex interplay of various factors, including peripheral neuropathy, peripheral arterial disease, foot deformities, impaired wound healing, and poor glycemic control...
January 2024: Journal of Orthopaedic Case Reports
https://read.qxmd.com/read/38288358/the-potential-of-autologous-platelet-rich-plasma-gel-for-diabetic-foot-ulcer-care-among-older-adults-a-systematic-review-and-meta-analysis
#39
REVIEW
Hesti Platini, Keyzha Amartya Adammayanti, Sidik Maulana, Putu Moradha Kharisma Putri, Welly Grivin Layuk, Juan Alessandro Jeremis Maruli Nura Lele, Hartiah Haroen, Sri Hartati Pratiwi, Faizal Musthofa, Arpit Mago
INTRODUCTION: Poorly controlled diabetes mellitus can lead to the development of diabetic foot ulcers (DFU), which is a frequent complication in patients. However, several diabetes management guidelines for older adults do not mention the occurrence of DFUs. Nowadays, Autologous Platelet-Rich Gel (APG) is being used for treating diabetic ulcers. APG is an innovative platelet-derived product with many advantages, such as being low-cost, easy to produce, and readily available materials...
2024: Therapeutics and Clinical Risk Management
https://read.qxmd.com/read/38285493/effectiveness-of-a-continuous-remote-temperature-monitoring-program-to-reduce-foot-ulcers-and-amputations-multicenter-postmarket-registry-study
#40
JOURNAL ARTICLE
Chia-Ding Shih, Henk Jan Scholten, Gavin Ripp, Kirthana Srikanth, Caileigh Smith, Ran Ma, Jie Fu, Alexander M Reyzelman
BACKGROUND: Neuropathic foot ulcers are the leading cause of nontraumatic foot amputations, particularly among patients with diabetes. Traditional methods of monitoring and managing these patients are periodic in-person clinic visits, which are passive and may be insufficient for preventing neuropathic foot ulcers and amputations. Continuous remote temperature monitoring has the potential to capture the critical period before the foot ulcers develop and to improve outcomes by providing real-time data and early interventions...
January 29, 2024: JMIR Diabetes
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