keyword
MENU ▼
Read by QxMD icon Read
search

Management diabetic foot ulcer

keyword
https://www.readbyqxmd.com/read/28930549/growth-factors-in-the-pathogenesis-of-diabetic-foot-ulcers
#1
Min Qi, Qiuhong Zhou, Weiqi Zeng, Lisha Wu, Shuang Zhao, Wangqing Chen, Chang Luo, Minxue Shen, Jianglin Zhang, Can-E Tang
Foot ulcers affect 15% of patients with diabetes, resulting in a great health burden. The occurrence and development of diabetic foot ulcers is associated with neuropathy, peripheral arterial disease, and infection. Several growth factors are involved in these processes, including epidermal growth factor, vascular endothelial growth factor, transforming growth factor-beta, fibroblast growth factor, and erythropoietin, which could promote wound healing of patients with diabetes. Thus, this review discusses the role of these growth factors in the pathogenesis of diabetic foot ulcers, aiming to achieve novel insights into the management of diabetic foot ulcers...
January 1, 2018: Frontiers in Bioscience (Landmark Edition)
https://www.readbyqxmd.com/read/28895073/efficacy-and-time-sensitivity-of-amniotic-membrane-treatment-in-patients-with-diabetic-foot-ulcers-a-systematic-review-and-meta-analysis
#2
REVIEW
Irakoze Laurent, Manirakiza Astère, Kan Ran Wang, Qing-Feng Cheng, Qi Fu Li
INTRODUCTION: Diabetic foot ulcers (DFUs) are complex chronic wounds which have a major long-term impact on the morbidity, mortality and quality of patients. The objective of this study was to assess the efficacy and time sensitivity of human amnion/chorion membrane treatment in patients with chronic DFUs. METHODS: The Cochrane Library, PubMed, Embase and Web of Science databases were systematically searched to identify relevant articles up to 10 April 2017. All randomized controlled trials (RCTs) comparing human amnion/chorion membrane + standard therapy and standard therapy alone in patients with DFUs were included in the analysis...
September 11, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28892986/diagnostic-accuracy-and-surgical-utility-of-mri-in-complicated-diabetic-foot
#3
Mayank Mahendra, Rahul Singh
INTRODUCTION: Diabetic foot complications pose a significant public health hazard and have negative effect on life quality. These complications are associated with increased risk of amputations and premature death. So focus is increasing on early treatment of complicated diabetic foot. AIM: To assess the diagnostic accuracy and surgical utility of MRI in complicated diabetic foot. MATERIALS AND METHODS: Thirty four complicated diabetic patients were evaluated prospectively...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28892930/the-impact-of-three-month-training-programme-on-foot-care-and-self-efficacy-of-patients-with-diabetic-foot-ulcers
#4
Raziyeh Sadat Bahador, Seyedeh Sara Afrazandeh, Nezar Ghanbarzehi, Maryam Ebrahimi
INTRODUCTION: Patient's self-efficacy in disease management and foot care is considered as an important indicator in controlling the complications of diabetes. AIM: This study was aimed to determine the effect of three-month training programme on foot care and self-efficacy of patients with diabetic foot ulcers. MATERIALS AND METHODS: A quasi-experimental study was conducted on 60 patients with diabetic foot ulcers in Jiroft Imam Khomeini hospital from January 2016 to May 2016...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889401/severity-of-drug-resistance-and-co-existence-of-enterococcus-faecalis-in-diabetic-foot-ulcer-infections
#5
Kavitha Shettigar, Deepika V Bhat, Kapaettu Satyamoorthy, Thokur Sreepathy Murali
The genes encoding aminoglycoside resistance in Enterococcus faecalis may promote collateral aminoglycoside resistance in polymicrobial wounds. We studied a total of 100 diabetic foot ulcer samples for infection and found 60 samples to be polymicrobial, 5 to be monomicrobial, and 35 samples to be culture negative. A total of 65 E. faecalis isolates were screened for six genes coding for aminoglycoside resistance, antibiotic resistance patterns, and biofilm production. Infectious Diseases Society of America/International Working Group on the Diabetic Foot system was used to classify the wound ulcers...
September 9, 2017: Folia Microbiologica
https://www.readbyqxmd.com/read/28880596/does-baseline-hemoglobin-a1c-level-predict-diabetic-foot-ulcer-outcome-or-wound-healing-time
#6
Lourdes Vella, Alfred Gatt, Cynthia Formosa
BACKGROUND: We sought to evaluate the relationship between baseline hemoglobin A1c (HbA1c) level and clinical outcomes, including foot ulcer outcome (resolved versus unresolved) and wound-healing time, in individuals with type 2 diabetes. METHODS: A prospective observational study was conducted on 99 patients presenting with a diabetic foot ulceration. Patient and ulcer characteristics were recorded. Patients were followed up for a maximum of 1 year. RESULTS: After 1 year of follow-up, 77% of ulcers healed and 23% did not heal...
July 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28862980/management-of-chronic-wounds-diagnosis-preparation-treatment-and-follow-up
#7
Subhas Gupta, Charles Andersen, Joyce Black, Jean de Leon, Caroline Fife, John C Lantis Ii, Jeffrey Niezgoda, Robert Snyder, Bauer Sumpio, William Tettelbach, Terry Treadwell, Dot Weir, Ronald P Silverman
Management of chronic wounds remains challenging in terms of prevalence and complexity. Considerable progress has been made in understanding the science of wound healing during the past decade, sparking volumes of publications and the development of hundreds of dressing and therapy options. There is a need for a simpli ed overview of evidence-based criteria to assist in the accurate diagnosis and appropriate management of chronic wounds in all care settings. An expert panel of 11 wound healing specialists experienced in various care settings convened to discuss best practices and recommended guidelines for managing major chronic wound types...
September 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28862974/clostridial-collagenase-for-the-management-of-diabetic-foot-ulcers-results-of-four-randomized-controlled-trials
#8
John C Lantis Ii, Ian Gordon
BACKGROUND: Despite major treatment advances, diabetic foot ulcers (DFUs) remain a frequent and debilitating complication of diabetes mellitus and a major cause of significant morbidity and mortality. OBJECTIVE: This study evaluates and compares clinical effectiveness of clostridial collagenase ointment (CCO) with standard care (SC) in patients with DFUs, with the goal to define best clinical criteria under which to use CCO in the DFU population. MATERIALS AND METHODS: This is a pooled data analysis of 4 randomized controlled trials that compared clinical effectiveness of CCO to SC...
August 25, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28842094/case-study-rare-case-of-mantle-cell-lymphoma-with-extranodal-involvement-in-the-foot
#9
Pauline Fu, Danielle Mercado, Vera Malezhik, Abul Ala Syed Rifat Mannan
Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma that commonly affects extranodal sites. The most commonly affected sites are the bone marrow, gastrointestinal tract, Waldeyer's ring, lung, and pleura. We report the case of an 80-year-old diabetic male, in MCL remission, who presented with a small dome-shaped nodule on his calf and an ipsilateral second digit non-healing ulceration after a traumatic fall. Despite surgical and conservative treatment, the wound worsened, resulting in histopathologic examination, which confirmed the presence of lymphocytes, indicating MCL relapse...
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28791310/prevalence-of-diabetic-foot-ulcer-and-associated-factors-among-adult-diabetic-patients-who-attend-the-diabetic-follow-up-clinic-at-the-university-of-gondar-referral-hospital-north-west-ethiopia-2016-institutional-based-cross-sectional-study
#10
Tesfamichael G Mariam, Abebaw Alemayehu, Eleni Tesfaye, Worku Mequannt, Kiber Temesgen, Fisseha Yetwale, Miteku Andualem Limenih
Diabetes mellitus is a metabolic disorder which is characterized by multiple long-term complications that affect almost every system in the body. Foot ulcers are one of the main complications of diabetes mellitus. However, there is limited evidence on the occurrence of foot ulcer and influencing factors in Ethiopia. An institutional-based cross-sectional study was conducted in Gondar University Hospital, Ethiopia, to investigate foot ulcer occurrence in diabetic patients. Systematic random sampling was used to select 279 study participants...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/28727481/leucocyte-and-platelet-rich-fibrin-l-prf-as-a-regenerative-medicine-strategy-for-the-treatment-of-refractory-leg-ulcers-a-prospective-cohort-study
#11
Nelson R Pinto, Matias Ubilla, Yelka Zamora, Verónica Del Rio, David M Dohan Ehrenfest, Marc Quirynen
Chronic wounds (VLU: venous leg ulcer, DFU: diabetic foot ulcer, PU: pressure ulcer, or complex wounds) affect a significant proportion of the population. Despite appropriate standard wound care, such ulcers unfortunately may remain open for months or even years. The use of leukocyte- and platelet-rich fibrin (L-PRF) to cure skin ulcers is a simple and inexpensive method, widely used in some countries but unknown or neglected in most others. This auto-controlled prospective cohort study explored and quantified accurately for the first time the adjunctive benefits of topical applications of L-PRF in the management of such refractory ulcers in a diverse group of patients...
July 20, 2017: Platelets
https://www.readbyqxmd.com/read/28704763/symptoms-of-anxiety-and-depression-in-type-2-diabetes-associations-with-clinical-diabetes-measures-and-self-management-outcomes-in-the-norwegian-hunt-study
#12
Kiyuri Naicker, Simon Øverland, Jeffrey A Johnson, Douglas Manuel, Jens C Skogen, Børge Sivertsen, Ian Colman
OBJECTIVE: To determine if symptoms of depression and anxiety are differentially associated with clinical diabetes measures and self-management behaviours in individuals with Type 2 diabetes, and whether these associations vary by patient sex. RESEARCH DESIGN AND METHODS: A cross-sectional analysis using data from 2035 adults with Type 2 diabetes in the Nord-Trøndelag Health Study. Multivariate logistic regression was used to explore associations between symptoms of depression and anxiety and waist girth, HDL cholesterol, systolic blood pressure, triglycerides, c-reactive protein, glycemic control, diet adherence, exercise, glucose monitoring, foot checks for ulcers, and the subjective patient experience...
July 6, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28704149/amputation-predictors-in-diabetic-foot-ulcers-treated-with-hyperbaric-oxygen
#13
S T Kaplan, D Hemsinli, S Kaplan, A Arslan
OBJECTIVE: Although hyperbaric oxygen therapy (HBOT) has long been used for diabetic foot ulcers (DFUs), its effectiveness is still controversial. The aim of this study was to investigate the efficacy of HBOT in the management of DFUs and identify amputation predictors. METHOD: Patients with chronic DFUs (Wanger grade 2-5) were included in the study, which took place between January 2010 and December 2012. HBOT, 100% oxygen, 2.4 atmosphere absolute (ATA) for 120 minutes, was administered to all patients in addition to standard treatment...
July 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28696493/total-contact-cast-system-to-heal-diabetic-foot-ulcers
#14
Brock Liden
Off-loadinga diabetic foot ulcer is a cornerstone of quality wound care for diabetic patients to allow cellular growth in the wound bed. While total contact casts (TCC) have been described as the gold standard for off-loading the wound, the complexity of application and the time commitment for both application and drying have discouraged health professionals from using them. This retrospective case series, conducted in a podiatric practice, evaluated using a TCC system that helps address the three components in which guidelines should be addressed when caring for a diabetic foot: V - vascular management, I - infection management and prevention, and P - pressure relief...
July 25, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28676002/recent-advances-in-polymer-based-wound-dressings-for-the-treatment-of-diabetic-foot-ulcer-an-overview-of-state-of-the-art
#15
Zahid Hussain, Hnin Ei Thu, Ahmad Nazrun Shuid, Haliza Katas, Fahad Hussain
Diabetic foot ulcers (DFUs) are the chronic, non-healing complications of diabetic mellitus which compels a significant burden to the patients and the healthcare system. Peripheral vascular disease, diabetic neuropathy, and abnormal cellular and cytokine/chemokine activity are among the prime players which exacerbate the severity and prevent wound reapir. Unlike acute wounds, DFUs impose a substantial challenge to the conventional wound dressings and demand the development of novel and advanced wound healing modalities...
July 4, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28669781/prevalence-of-diabetic-retinopathy-and-blindness-in-indonesian-adults-with-type-2-diabetes
#16
Muhammad Bayu Sasongko, Felicia Widyaputri, Angela Nurini Agni, Firman Setya Wardhana, Satyaprabha Kotha, Prateek Gupta, Tri Wahyu Widayanti, Supanji Haryanto, Rifa Widyaningrum, Tien Yin Wong, Ryo Kawasaki, Jie Jin Wang
PURPOSE: To report the prevalence of diabetic retinopathy (DR) and DR-related blindness in an Indonesian population with type 2 diabetes. METHODS: Design: Population-based cross-sectional study. SETTING: Community health centers. STUDY POPULATION: We recruited 1184 people aged older than 30 years with type 2 diabetes residing in Jogjakarta, Indonesia. Multistage, clustered random sampling based on regencies and districts in Jogjakarta was used...
September 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28650752/characteristics-predicting-the-outcome-in-individuals-with-diabetic-foot-ulcerations
#17
Lourdes Vella, Cynthia Formosa
BACKGROUND: We sought to determine patient and ulcer characteristics that predict wound healing in patients living with diabetes. METHODS: A prospective observational study was conducted on 99 patients presenting with diabetic foot ulceration. Patient and ulcer characteristics were recorded. Patients were followed up for a maximum of 1 year. RESULTS: After 1 year of follow-up, ulcer characteristics were more predictive of ulcer healing than were patient characteristics...
May 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28644115/evaluation-of-the-effectiveness-and-cost-effectiveness-of-lightweight-fibreglass-heel-casts-in-the-management-of-ulcers-of-the-heel-in-diabetes-a-randomised-controlled-trial
#18
William Jeffcoate, Frances Game, Vivienne Turtle-Savage, Alison Musgrove, Patricia Price, Wei Tan, Lucy Bradshaw, Alan Montgomery, Deborah Fitzsimmons, Angela Farr, Thomas Winfield, Ceri Phillips
BACKGROUND: Ulcers of the foot in people with diabetes mellitus are slow to heal and result in considerable cost and patient suffering. The prognosis is worst for ulcers of the heel. OBJECTIVE: To assess both the clinical effectiveness and the cost-effectiveness of lightweight fibreglass casts in the management of heel ulcers. DESIGN: A pragmatic, multicentre, parallel, observer-blinded randomised controlled trial. A central randomisation centre used a computer-generated random number sequence to allocate participants to groups...
May 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28643380/microscopy-visualisation-confirms-multi-species-biofilms-are-ubiquitous-in-diabetic-foot-ulcers
#19
Khalid Johani, Matthew Malone, Slade Jensen, Iain Gosbell, Hugh Dickson, Honhua Hu, Karen Vickery
Increasing evidence within the literature has identified the presence of biofilms in chronic wounds and proposed that they contribute to delayed wound healing. This research aimed to investigate the presence of biofilm in diabetic foot ulcers (DFUs) using microscopy and molecular approaches and define if these are predominantly mono- or multi-species. Secondary objectives were to correlate wound observations against microscopy results in ascertaining if clinical cues are useful in detecting wound biofilm. DFU tissue specimens were obtained from 65 subjects...
June 23, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28627227/smarter-sole-survival-will-neuropathic-patients-at-high-risk-for-ulceration-use-a-smart-insole-based-foot-protection-system
#20
Bijan Najafi, Eyal Ron, Ana Enriquez, Ivan Marin, Javad Razjouyan, David G Armstrong
OBJECTIVE: This study examined adherence to alert-based cues for plantar pressure offloading in patients with diabetic foot disease. METHOD AND DESIGN: Participants (n = 17) with in diabetic foot remission (history of neuropathic ulceration) were instructed to wear a smart insole system (the SurroSense Rx, Orpyx Medical Technologies Inc, Calgary, Canada) over a three-month period. This device is designed to cue offloading to manage unprotected sustained plantar pressures in an effort to prevent foot ulceration...
July 2017: Journal of Diabetes Science and Technology
keyword
keyword
101078
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"