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Prevention diabetic foot ulcer

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https://www.readbyqxmd.com/read/29791033/diabetes-related-lower-extremity-complications-are-a-leading-cause-of-the-global-burden-of-disability
#1
P A Lazzarini, R E Pacella, D G Armstrong, J J van Netten
Globally ~435 million people have diabetes [1], and an estimated 19-34% (~83-148 million people) of those will be expected to develop foot ulcers in their lifetime [2]. Foot ulcers are typically precipitated by other diabetes-related lower-extremity complications, (DRLECs) including peripheral neuropathy and peripheral vascular disease [2,3]. Collectively, DRLECs are a leading cause of infection, hospitalization and amputation outcomes [2-5], yet, these outcomes are readily preventable with evidence-based care [6,7]...
May 23, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29718822/remote-temperature-monitoring-in-diabetic-foot-ulcer-detection
#2
Amanda L Killeen, Jodi L Walters
INTRODUCTION: Diabetic foot ulcers (DFUs) are associated with increased morbidity, mortality, and resource utilization. Remote temperature monitoring (RTM) is an evidence-based and recommended component of standard preventative foot care for high-risk populations that can detect the inflammation preceding and accompanying DFUs. OBJECTIVE: This case series illustrates the use of a RTM foot mat for the early detection and prevention of DFUs in patients with a history of DFUs...
April 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/29696071/building-a-scalable-diabetic-limb-preservation-program-four-steps-to-success
#3
Tanzim Khan, Laura Shin, Stephanie Woelfel, Vincent Rowe, Brittany L Wilson, David G Armstrong
Over the past generation, limb preservation programs and diabetic foot services have begun to proliferate within academic health science centers as well as within health-care systems in general. We describe four key components for a successful program that, developed sequentially with temporal overlap, can allow the program to scale. The first component includes establishment of a 'hot foot line' for urgent emergency department/inpatient referral. The second includes development of a wound-healing clinic to address outpatient care through to remission...
2018: Diabetic Foot & Ankle
https://www.readbyqxmd.com/read/29611155/managing-the-diabetic-foot-ulcer-how-best-practices-fit-the-real-2018-united-states
#4
Nicole Ilonzo, Munir Patel, John C Lantis
Diabetes Mellitus is a serious systemic illness that has an epidemic-like increasing prevalence in the United States, as well as the rest of the world. With the increasing number of people with diabetes comes the higher incidence of diabetes-related complications. One of these known complications, diabetic foot ulcers (DFU), has an estimated lifetime incidence of 15% in diabetics. Having a DFU increases the risk of infection, amputation, and even death, which is why prompt treatment and surveillance of such ulcers is imperative...
March 29, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29569418/monitoring-of-ph-and-temperature-of-neuropathic-diabetic-and-non-diabetic-foot-ulcers-for-12-weeks-an-observational-study
#5
G Gethin, G M O'Connor, J Abedin, J Newell, L Flynn, D Watterson, A O'Loughlin
Wound bed assessment is largely reliant on subjective interpretation without recourse to objective tools or biomarkers. The identification of a point of care, reliable biomarker would enhance assessment and ultimately clinical decision-making. Two potentially emerging wound biomarkers exist: surface pH and surface temperature. To date, knowledge of their use has been predominantly in wound prevention, in vitro studies and single time measurements. Our objective was to determine surface pH, size and surface temperature in non-infected, neuropathic foot ulcers at baseline and at 12 weeks...
March 22, 2018: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/29566422/clinical-prospective-study-on-the-use-of-subcutaneous-carboxytherapy-in-the-treatment-of-diabetic-foot-ulcer
#6
Lynda Khiat, Gustavo H Leibaschoff
Diabetic footfoot ulcer (DFU) is a serious complication of diabetes mellitus, and possibly the major morbidity of the diabetic foot. It is the most common foot injury in diabetic patients and can lead to lower-extremity amputation. Management of DFU requires a systematic knowledge of the major risk factors for amputation, frequent routine evaluation, scrupulous preventive maintenance, and correction of peripheral arterial insufficiency. Carboxytherapy refers to the subcutaneous injection of CO2 to improve the microcirculation and promote wound-healing by stimulating the microcirculation...
March 22, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29564949/prevalence-clinical-presentation-and-factors-associated-with-diabetic-foot-ulcer-in-two-regional-hospitals-in-cameroon
#7
Maxime Tindong, John N Palle, Daniel Nebongo, Leopold Ndemnge Aminde, Yannick Mboue-Djieka, Nicole T Fouda Mbarga, Mesmin Y Dehayem, Siméon-Pierre Choukem
This study aimed to determine the prevalence of diabetic foot ulcer and high risk for ulceration, describe the clinical presentation, and identify factors associated with diabetic foot ulcer in the Southwest regional hospitals of Cameroon. In this cross-sectional study, data were collected using a structured questionnaire administered to consecutive patients with diabetes. Findings from detailed foot examination were recorded. Diabetic foot ulcer was diagnosed according to the International Working Group on Diabetic Foot (IWGDF) definition...
March 1, 2018: International Journal of Lower Extremity Wounds
https://www.readbyqxmd.com/read/29563821/decreased-health-related-quality-of-life-in-patients-with-diabetic-foot-problems
#8
Jin Sothornwit, Gulapar Srisawasdi, Atchara Suwannakin, Apiradee Sriwijitkamol
Purpose: The aim of this study was to investigate health-related quality of life (HRQoL) in patients with diabetic foot problems and compare the HRQoL between diabetic patients with: 1) diabetic foot problems (DF), including diabetic foot ulcer (DFU) or amputation (AMPU); 2) other diabetic complications (COM), such as diabetic retinopathy (DR), end-stage renal disease (ESRD), or coronary artery disease (CAD); and 3) no diabetic complication (CON). Patients and methods: A total of 254 diabetic patients were studied in a cross-sectional setting...
2018: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29559450/current-challenges-and-opportunities-in-the-prevention-and-management-of-diabetic-foot-ulcers
#9
William J Jeffcoate, Loretta Vileikyte, Edward J Boyko, David G Armstrong, Andrew J M Boulton
Diabetic foot ulcers remain a major health care problem. They are common, result in considerable suffering, frequently recur, and are associated with high mortality, as well as considerable health care costs. While national and international guidance exists, the evidence base for much of routine clinical care is thin. It follows that many aspects of the structure and delivery of care are susceptible to the beliefs and opinion of individuals. It is probable that this contributes to the geographic variation in outcome that has been documented in a number of countries...
April 2018: Diabetes Care
https://www.readbyqxmd.com/read/29535941/effectiveness-of-a-patient-education-module-on-diabetic-foot-care-in-outpatient-setting-an-open-label-randomized-controlled-study
#10
Hammadur Sk Rahaman, Viveka P Jyotsna, V Sreenivas, Anand Krishnan, Nikhil Tandon
Background: A large number of patients with diabetes mellitus are unaware of foot care and are at risk of developing foot ulcer and amputation. This increases healthcare burden due to preventable complication of diabetes. Aims: We conducted this study to assess the effectiveness of a foot care education module for diabetes developed by us. Materials and Methods: One hundred and twenty-seven patients with diabetes mellitus attending our outpatient were randomized into intervention ( n = 63) and control groups ( n = 64)...
January 2018: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29521041/computerized-planimetry-evaluation-of-hyperbaric-oxygen-therapy-in-the-treatment-of-diabetic-foot
#11
Marek Kawecki, Jarosław Pasek, Grzegorz Cieślar, Aleksander Sieroń, Grzegorz Knefel, Mariusz Nowak, Justyna Glik
BACKGROUND: Diabetic foot ulcer is one of the major complications of diabetes mellitus in adults. OBJECTIVES: The aim of the study was to conduct a planimetry evaluation of the effectiveness of hyperbaric oxygen therapy (HBOT) in the treatment of patients with vascular disorders caused by diabetic foot. MATERIAL AND METHODS: The study included 94 patients, 30 females (32%) and 64 males (68%), aged 33-76 years, with diabetes lasting 1.5-32 years, who underwent HBOT due to diabetic foot...
January 2018: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29505922/involvement-of-growth-factors-in-diabetes-mellitus-and-its-complications-a-general-review
#12
REVIEW
Guang-Jiang Shi, Guang-Rui Shi, Jia-Yin Zhou, Wen-Jin Zhang, Chen-Ying Gao, Ya-Ping Jiang, Zhen-Guo Zi, Hai-Hong Zhao, Yong Yang, Jian-Qiang Yu
Diabetes mellitus (DM) is a major endocrine metabolic disease and is marked by a lack of insulin. The complication of DM is one of the most difficult problems in medicine. The initial translational studies revealed that growth factors have a major role in integrating tissue physiology and in embryology as well as in growth, maturation and tissue repair. In some tissues affected by diabetes, growth factors are induced by a relative deficit or excess. Fibroblast growth factor 21 (FGF21) is a promising regulator of glucose and lipid metabolism with multiple beneficial effects including hypoglycemic and lipid-lowering...
May 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29504308/single-sensor-gait-analysis-to-detect-diabetic-peripheral-neuropathy-a-proof-of-principle-study
#13
Patrick Esser, Johnny Collett, Kevin Maynard, Dax Steins, Angela Hillier, Jodie Buckingham, Garry D Tan, Laurie King, Helen Dawes
This study explored the potential utility of gait analysis using a single sensor unit (inertial measurement unit [IMU]) as a simple tool to detect peripheral neuropathy in people with diabetes. Seventeen people (14 men) aged 63±9 years (mean±SD) with diabetic peripheral neuropathy performed a 10-m walk test instrumented with an IMU on the lower back. Compared to a reference healthy control data set (matched by gender, age, and body mass index) both spatiotemporal and gait control variables were different between groups, with walking speed, step time, and SDa (gait control parameter) demonstrating good discriminatory power (receiver operating characteristic area under the curve >0...
February 2018: Diabetes & Metabolism Journal
https://www.readbyqxmd.com/read/29503134/squamous-cell-carcinoma-from-marjolin-s-ulcer-of-the-foot-in-a-diabetic-patient-case-study
#14
Raymond Cavaliere, Danielle M Mercado, Malary Mani
Squamous cell carcinoma (SCC) has been commonly reported by foot and ankle specialists. Marjolin's ulcer is a malignancy that involves a posttraumatic scar or ulceration that can develop into SCC from chronic neuropathic pedal wounds, venous stasis, or decubitus ulcerations. Most Marjolin's ulcers are found in the lower extremity, specifically the feet, and it is twice as common in females as males. Biopsy of the tumor is the reference standard to diagnose SCC, and wide excision of SCC is the most common treatment option...
March 2, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29477503/physical-activity-and-exercise-on-diabetic-foot-related-outcomes-a-systematic-review
#15
REVIEW
Monica Matos, Romeu Mendes, André B Silva, Nelson Sousa
BACKGROUND: Diabetic foot is one of the most common complications of diabetes. It has the potential risk of pathologic consequences including infection, ulceration and amputation, but a growing body of evidence suggests that physical activity and exercise may improve diabetic foot outcomes. OBJECTIVE: To analyze de effects of exercise and physical activity interventions on diabetic foot outcomes. METHODS: A comprehensive and systematic search was conducted according to PRISMA recommendations...
February 23, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29439130/limb-and-person-level-risk-factors-for-lower-limb-amputation-in-the-prospective-seattle-diabetic-foot-study
#16
Edward J Boyko, Amber D Seelig, Jessie H Ahroni
OBJECTIVE: Diabetes is the leading cause of nontraumatic lower-limb amputations in the U.S., but no research has prospectively examined associations between limb-specific measurements and amputation risk among patients without foot ulcer. We investigated amputation risk by limb in relation to the same limb- and person-level factors. RESEARCH DESIGN AND METHODS: We conducted a 22-year prospective study among 1,461 male patients with diabetes without foot ulcer (mean age 62...
April 2018: Diabetes Care
https://www.readbyqxmd.com/read/29410772/the-abrupt-temperature-changes-in-the-plantar-skin-thermogram-of-the-diabetic-patient-looking-in-to-prevent-the-insidious-ulcers
#17
REVIEW
Francisco-J Renero-C
Background: One of the complications of the diabetes mellitus is the amputation of the lower limbs. This complication may be developed after an insidious ulcer, that may be raised by the peripheral neuropathy or the ischaemic limb, and that the ulcer get infected. That is, to develop an ulcer, in the diabetic patient, three factors should be taken into the account, the autonomic nervous system, the blood supply and the inmune system. Methods: In this work, the thermogram is used to identify regions on the plantar skin with blood supply deficiencies and the behaviour of the thermoregulation process...
2018: Diabetic Foot & Ankle
https://www.readbyqxmd.com/read/29402807/recent-advances-and-future-opportunities-to-address-challenges-in-offloading-diabetic-feet-a-mini-review
#18
Ryan T Crews, Abagayle L King, Sai V Yalla, Noah J Rosenblatt
Diabetic foot ulcers (DFU) are a substantial dilemma for geriatric individuals with diabetes. The breakdown in tissue associated with DFU is typically a result of repetitive cycles of physical stress placed on the feet during weight-bearing activity. Accordingly, a key tenet in healing as well as preventing DFU is the use of offloading footwear to redistribute physical stress away from high stress locations such as bony prominences. Over the last several years there has been a substantial amount of effort directed at better understanding and implementing the practice of offloading...
January 16, 2018: Gerontology
https://www.readbyqxmd.com/read/29399663/can-diabetes-be-controlled-by-lifestyle-activities
#19
P Hemachandra Reddy
Diabetes is a complex disease that affects millions of people worldwide. Diabetes is a metabolic disease, in which increased blood glucose levels ultimately lead to heart disease, stroke, kidney failure, foot ulcers, and damage to the eyes. Current prevalence rates of diabetes are extremely high in countries throughout the world. Multiple forms of diabetes have been identified, including type 1, type 2, type 3, neonatal and gestational. The purpose of this article is to discuss recent developments in diabetes research, including prevalence, morbidity and mortality rates, and lifestyle factors that are associated with diabetes onset and progression...
March 2017: Current Research in Diabetes & Obesity Journal
https://www.readbyqxmd.com/read/29371890/diabetic-foot-australia-guideline-on-footwear-for-people-with-diabetes
#20
Jaap J van Netten, Peter A Lazzarini, David G Armstrong, Sicco A Bus, Robert Fitridge, Keith Harding, Ewan Kinnear, Matthew Malone, Hylton B Menz, Byron M Perrin, Klaas Postema, Jenny Prentice, Karl-Heinz Schott, Paul R Wraight
Background: The aim of this paper was to create an updated Australian guideline on footwear for people with diabetes. Methods: We reviewed new footwear publications, (inter)national guidelines, and consensus expert opinion alongside the 2013 Australian footwear guideline to formulate updated recommendations. Result: We recommend health professionals managing people with diabetes should: (1) Advise people with diabetes to wear footwear that fits, protects and accommodates the shape of their feet...
2018: Journal of Foot and Ankle Research
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