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Prevention diabetic foot ulcer

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https://www.readbyqxmd.com/read/28226977/establishment-of-a-measurement-method-for-in-shoe-pressure-and-shear-stress-in-specific-regions-for-diabetic-ulcer-prevention
#1
Ayumi Amemiya, Hiroshi Noguchi, Makoto Oe, Hiromi Sanada, Taketoshi Mori, Ayumi Amemiya, Hiroshi Noguchi, Makoto Oe, Hiromi Sanada, Taketoshi Mori, Makoto Oe, Ayumi Amemiya, Hiromi Sanada, Hiroshi Noguchi, Taketoshi Mori
Pressure and shear stress are the factors of diabetic foot ulcers and callus formation. However, in-shoe shear stress of callus measurement could not have been measured because of technical difficulties. The purpose of this study is to verify reliability and validity of the established measurement system for in-shoe pressure and shear stress. For reliability, coefficients of variation (CV) and intraclass correlation coefficients (ICC) were confirmed. For known-groups validity, callus and non-callus feet were compared...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226763/detection-of-diabetic-foot-hyperthermia-by-using-a-regionalization-method-based-on-the-plantar-angiosomes-on-infrared-images
#2
Y Liu, A Polo, M Zequera, R Harba, R Canals, L Vilcahuaman, Y Bello, Y Liu, A Polo, M Zequera, R Harba, R Canals, L Vilcahuaman, Y Bello, A Polo, M Zequera, Y Liu, Y Bello, R Canals, L Vilcahuaman, R Harba
Prevention of serious diabetic foot complication like ulceration or infection is an important issue. As the development of thermal graphic technologies, foot temperature-guided avoidance therapy has been recommended. Doctors from Hospital National Dos de Mayo are studying on the risk of the diabetic foot passing from Grade 0 to Grade 1 in the Wagner Scale. This risk to develop ulcers is related to the temperature difference of corresponding area between left and right foot. Generally speaking, the diabetic foot with greater mean temperature difference has more potential to develop ulcers; especially, area whose temperature difference of more than 2...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226762/the-use-of-a-thermal-camera-and-eulerian-enhancement-in-the-examination-of-pedal-pulse-and-microvascular-health
#3
Stephanie L Bennett, Rafik A Goubran, Brendan Bennett, Rebecca A Bennett, Frank Knoefel, Stephanie L Bennett, Rafik A Goubran, Brendan Bennett, Rebecca A Bennett, Frank Knoefel, Stephanie L Bennett, Rafik A Goubran, Brendan Bennett, Rebecca A Bennett, Frank Knoefel
Early detection of impaired blood flow and microvascular functioning is important to prevent ulceration in diabetic patients. This paper aims to first determine if thermal video in conjunction with Eulerian Video Magnification (EVM) can be used to find the pedal pulse rate, and reveal patterns indicative of the foot's microvascular health. Thermal video was captured of a healthy adult's foot while a Doppler ultrasound captured pedal pulse. Another thermal video was captured of a patient's heels. These videos were subjected to EVM, areas of interest were defined and the mean intensity signal was calculated temporally, within each defined area...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224724/economic-and-social-impact-of-diabetes-mellitus-in-a-low-income-country-a-case-control-study-in-sudan
#4
Hind Elrayah-Eliadarous, Claes-Göran Östensson, Mohamed Eltom, Pia Johansson, Vibeke Sparring, Rolf Wahlström
AIMS: Diabetes mellitus accounts for 11% of total health expenditures worldwide, and the majority of all persons with diabetes live in low- and middle-income countries. This study examined the economic and social impact attributed to diabetes in Sudan by calculating out-of-pocket medical expenditures and the health and social impact of the disease for persons with diabetes (n = 375) and their families, compared to a non-diabetic control group (n = 375), matched for age, sex and residence area...
February 22, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28216809/healing-ulcers-and-preventing-their-recurrences-in-the-diabetic-foot
#5
S Raja Sabapathy, Madhu Periasamy
Fifteen percent of people with diabetes develop an ulcer in the course of their lifetime. Eighty-five percent of the major amputations in diabetes mellitus are preceded by an ulcer. Management of ulcers and preventing their recurrence is important for the quality of life of the individual and reducing the cost of care of treatment. The main causative factors of ulceration are neuropathy, vasculopathy and limited joint mobility. Altered bio-mechanics due to the deformities secondary to neuropathy and limited joint mobility leads to focal points of increased pressure, which compromises circulation leading to ulcers...
September 2016: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28166662/-ischemic-origin-of-diabetic-foot-disease-epidemiology-difficulties-of-diagnosis-options-for-prevention-and-revascularization
#6
Endre Kolossváry, Zoltán Bánsághi, Gábor Viktor Szabó, Zoltán Járai, Katalin Farkas
"Diabetic foot" as definition covers a multifactorial clinical condition. According to the recent epidemiological data, the role of lower limb ischemia is getting more influential over other pathological causes, like neuropathy, infections and bone or soft tissue deformity. In diabetes, vascular disease leads to increased risk for leg ulcers and minor or major amputations. The traditional diagnostic tools for recognition of peripheral arterial disease have limited value because of diabetes specific clinical manifestations...
February 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28165050/terahertz-imaging-for-early-screening-of-diabetic-foot-syndrome-a-proof-of-concept
#7
G G Hernandez-Cardoso, S C Rojas-Landeros, M Alfaro-Gomez, A I Hernandez-Serrano, I Salas-Gutierrez, E Lemus-Bedolla, A R Castillo-Guzman, H L Lopez-Lemus, E Castro-Camus
Most people with diabetes suffer some deterioration of the feet. Diabetic foot syndrome causes ulceration in about 15% of cases and such deterioration leads to amputation in about 2.5% of diabetic patients, diminishing their quality of life and generating extraordinary costs for patients and public health systems. Currently, there is no objective method for the detection of diabetic foot syndrome in its early stages. We propose terahertz imaging as a method for the evaluation of such deterioration. This screening method could aid the prevention and medical treatment of this condition in the future...
February 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28153676/a-model-to-estimate-cost-savings-in-diabetic-foot-ulcer-prevention-efforts
#8
Neal R Barshes, Samira Saedi, James Wrobel, Panos Kougias, O Erhun Kundakcioglu, David G Armstrong
BACKGROUND: Sustained efforts at preventing diabetic foot ulcers (DFUs) and subsequent leg amputations are sporadic in most health care systems despite the high costs associated with such complications. We sought to estimate effectiveness targets at which cost-savings (i.e. improved health outcomes at decreased total costs) might occur. METHODS: A Markov model with probabilistic sensitivity analyses was used to simulate the five-year survival, incidence of foot complications, and total health care costs in a hypothetical population of 100,000 people with diabetes...
January 21, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28116957/prevention-and-treatment-of-diabetic-foot-ulcers
#9
Jonathan Zhang Ming Lim, Natasha Su Lynn Ng, Cecil Thomas
The rising prevalence of diabetes estimated at 3.6 million people in the UK represents a major public health and socioeconomic burden to our National Health Service. Diabetes and its associated complications are of a growing concern. Diabetes-related foot complications have been identified as the single most common cause of morbidity among diabetic patients. The complicating factor of underlying peripheral vascular disease renders the majority of diabetic foot ulcers asymptomatic until latter evidence of non-healing ulcers become evident...
January 1, 2017: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/28110181/dynamic-measurement-of-surface-strain-distribution-on-the-foot-during-walking
#10
Kohta Ito, Kosuke Maeda, Ikumi Fujiwara, Koh Hosoda, Takeo Nagura, Taeyong Lee, Naomichi Ogihara
To clarify the mechanism underlying the development of foot disorders such as diabetic ulcers and deformities, it is important to understand how the foot surface elongates and contracts during gait. Such information is also helpful for improving the prevention and treatment of foot disorders. We therefore measured temporal changes in the strain distribution on the foot surface during human walking. Five adult male participants walked across a glass platform placed over an angled mirror set in a wooden walkway at a self-selected speed and the dorsolateral and plantar surfaces of the foot were filmed using two pairs of synchronized high-speed cameras...
December 18, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28053300/a-medical-thermal-imaging-device-for-the-prevention-of-diabetic-foot-ulceration
#11
G Machin, A Whittam, S Ainarkar, J Allen, J Bevans, M Edmonds, B Kluwe, A Macdonald, N Petrova, P Plassmann, F Ring, L Rogers, R Simpson
In this paper a description is given of the development, characterisation and first results of a thermal imaging device aimed at significantly reducing the incidence of diabetic foot ulceration (DFU). These devices will be used in three clinical centres and in two preliminary clinical trials. The first will be on healthy volunteers to set a robust baseline for the overall research aims and the second on  >100 patients at high risk of DFU. In the second phase of the project the objective is to demonstrate significant reduction in the incidence of DFU through a comparison of the results of standard care of high risk feet with standard care plus thermal imaging...
January 5, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28029181/new-horizons-in-the-understanding-of-the-causes-and-management-of-diabetic-foot-disease-report-from-the-2017-diabetes-uk-annual-professional-conference-symposium
#12
REVIEW
M Clokie, A L Greenway, K Harding, N J Jones, K Vedhara, F Game, K K Dhatariya
Diabetes-related foot disease remains a common problem. For wounds, classic teaching recommends the treatment of any infection, offloading the wound and ensuring a good blood supply, as well as ensuring that the other modifiable risk factors are addressed and optimized. There remain, however, several questions about these and other aspects of the care of diabetes-related foot disease. Some of these questions are addressed in the present report; in particular, the impact of newer technologies in the identification of any organisms present in a wound, as well as the use of novel approaches to treat infections...
March 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28013263/invasive-systemic-infection-after-hospital-treatment-for-diabetic-foot-ulcer-risk-of-occurrence-and-effect-on-survival
#13
Shey-Ying Chen, John M Giurini, Adolf W Karchmer
BACKGROUND: Diabetic foot ulcers (DFUs) threaten limbs and prompt hospitalization. After hospitalization, remote-site invasive systemic infection related to DFU (DFU-ISI) may occur. The characteristics of DFU-ISIs and their effect on mortality risk have not been defined. METHODS: We conducted a retrospective cohort study of 819 diabetic patients hospitalized for treatment of 1212 unique DFUs during a 9-year period. We defined the index ulcer as that present at the first (index) DFU admission to our hospital...
February 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27941234/thermal-symmetry-of-healthy-feet-a-precursor-to-a-thermal-study-of-diabetic-feet-prior-to-skin-breakdown
#14
Audrey Macdonald, Nina Petrova, Suhail Ainarkar, John Allen, Peter Plassmann, Aaron Whittam, John Bevans, Francis Ring, Ben Kluwe, Rob Simpson, Leon Rogers, Graham Machin, Mike Edmonds
Early identification of areas of inflammation may aid prevention of diabetic foot ulcers. A new bespoke thermal camera system has been developed to thermally image feet at risk. Hotspots (areas at least 2.2 °C hotter than the contralateral site) may indicate areas of inflammation prior to any apparent visual signs. This article describes the thermal pattern and symmetry of 103 healthy pairs of feet. 68% of participants were thermally symmetric at the 33 foot sites measured. 32% of participants had at least one hotspot, but hotspots overall only accounted for 5% of the measurements made...
January 2017: Physiological Measurement
https://www.readbyqxmd.com/read/27921418/-diabetic-foot-syndrome-from-the-perspective-of-internist-educated-in-podiatry
#15
Alexandra Jirkovská
Podiatry is the science dealing with the diagnostics and treatment of the foot and ankle and associated tissues and structures by all appropriate methods and also with the local manifestation of the overall processes in this area. Diabetic foot disease is defined as infection, ulceration or destruction of tissues of the foot associated with neuropathy and/or peripheral artery disease in the lower extremity of people with diabetes according to the latest edition of the International Consensus. Successful treatment and prevention of diabetic foot syndrome depends on a holistic approach, in which it is seen as part of the multiple organ involvement...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27888790/complication-assessment-and-prevention-strategies-using-midfoot-fusion-bolt-for-medial-column-stabilization-in-charcot-s-osteoarthropathy
#16
Alexander T Mehlhorn, Markus Walther, Niklas Iblher, Norbert P Südkamp, Hagen Schmal
In Charcot's osteoarthropathy stabilization of the medial column of the foot was introduced in order to establish a stable foot and reduce the risk for amputation. This study was performed to analyze postoperative complications, define risk factors for those and develop strategies for prevention. Since bolt dislocation takes place frequently, it was aimed to predict an appropriate time point for bolt removal under the condition that osseous healing has occurred. Fourteen consecutive patients with neuroosteoarthropathy of the foot and arch collapse were treated with open reduction and stabilization using midfoot fusion bolt and lateral lag screws...
December 2016: Foot
https://www.readbyqxmd.com/read/27883358/negative-pressure-wound-therapy-inhibits-inflammation-and-upregulates-activating-transcription-factor-3-and-downregulates-nuclear-factor-%C3%AE%C2%BAb-in-diabetic-patients-with-foot-ulcerations
#17
T Wang, R He, J Zhao, J C Mei, M Z Shao, Y Pan, J Zhang, H S Wu, M Yu, W C Yan, L M Liu, F Liu, W P Jia
BACKGROUND: Negative pressure wound therapy (NPWT) is one of the most important treatments for diabetic foot, but the underlying mechanisms of its benefits still remain elusive. This study aims to evaluate the inflammatory signals involved in the effects of negative pressure therapy on diabetic foot ulcers. METHODS: We enrolled 22 patients with diabetic foot ulceration, 11 treated with NPWT and the other 11 treated with traditional debridement. All patients were treated and observed for 1 week...
November 24, 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/27871769/effect-of-mechanical-vibration-on-transcutaneous-oxygen-levels-in-the-feet-of-type-2-diabetes-mellitus-patients
#18
Gerardo Rodríguez Reyes, Lidia Núñez Carrera, Aldo Alessi Montero, Adriana Solís Vivanco, Ivett Quiñones Uriostegui, Alberto Isaac Pérez Sanpablo
BACKGROUND AND OBJECTIVE: Foot conditions in patients with diabetes mellitus (DM) are major causes of morbidity and disability. Whole body vibration may promote blood circulation in the lower limbs, hence facilitating perfusion and promoting the supply of nutrients and oxygen to comprised tissues. Transcutaneous oxygen levels (TcPO2)>40mmHg in cases of diabetic foot syndrome are associated with a good prognosis in the resolution of ulcers. The objective of this study was to determine whether whole body vibration favors some parameters of interest related to complications associated with the diabetic foot syndrome...
January 6, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/27849290/the-prevention-of-diabetic-foot-ulceration-how-biomechanical-research-informs-clinical-practice
#19
Frank E DiLiberto, Judith F Baumhauer, Deborah A Nawoczenski
Background: Implementation of interprofessional clinical guidelines for the prevention of neuropathic diabetic foot ulceration has demonstrated positive effects regarding ulceration and amputation rates. Current foot care recommendations are primarily based on research regarding the prevention of ulcer recurrence and focused on reducing the magnitude of plantar stress (pressure overload). Yet, foot ulceration remains to be a prevalent and debilitating consequence of Diabetes Mellitus...
November 16, 2016: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/27846299/hyperglycemia-induces-skin-barrier-dysfunctions-with-impairment-of-epidermal-integrity-in-non-wounded-skin-of-type-1-diabetic-mice
#20
Junko Okano, Hideto Kojima, Miwako Katagi, Takahiko Nakagawa, Yuki Nakae, Tomoya Terashima, Takeshi Kurakane, Mamoru Kubota, Hiroshi Maegawa, Jun Udagawa
Diabetes causes skin complications, including xerosis and foot ulcers. Ulcers complicated by infections exacerbate skin conditions, and in severe cases, limb/toe amputations are required to prevent the development of sepsis. Here, we hypothesize that hyperglycemia induces skin barrier dysfunction with alterations of epidermal integrity. The effects of hyperglycemia on the epidermis were examined in streptozotocin-induced diabetic mice with/without insulin therapy. The results showed that dye leakages were prominent, and transepidermal water loss after tape stripping was exacerbated in diabetic mice...
2016: PloS One
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