keyword
MENU ▼
Read by QxMD icon Read
search

noak

keyword
https://www.readbyqxmd.com/read/27917760/the-universities-of-stellenbosch-cape-town-low-carbohydrate-diet-review-mistake-or-mischief
#1
Z Harcombe, T D Noakes
A 2014 meta-analysis from the universities of Stellenbosch and Cape Town reported that diets with a lower-carbohydrate (CHO) content are no more effective for producing weight loss than are high-CHO diets, so-called isoenergetic 'balanced' diets. We have re-examined the article and found numerous errors, many material in nature. Studies were included that failed the authors' own inclusion criteria; invalid and subjective meta-analysis sub-grouping was used; and data extraction was repeatedly inaccurate. All but one error favoured the balanced diet...
December 1, 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27913293/differential-role-of-calpain-dependent-protein-cleavage-in-intermediate-and-long-term-operant-memory-in-aplysia
#2
Lisa C Lyons, Jacob S Gardner, Cassidy T Lentsch, Catherine E Gandour, Harini C Krishnan, Eric J Noakes
In addition to protein synthesis, protein degradation or protein cleavage may be necessary for intermediate (ITM) and long-term memory (LTM) to remove molecular constraints, facilitate persistent kinase activity and modulate synaptic plasticity. Calpains, a family of conserved calcium dependent cysteine proteases, modulate synaptic function through protein cleavage. We used the marine mollusk Aplysia californica to investigate the in vivo role of calpains during intermediate and long-term operant memory formation using the learning that food is inedible (LFI) paradigm...
November 29, 2016: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/27900189/novel-coaching-cricket-bat-can-it-be-used-to-enhance-the-backlift-and-performance-of-junior-cricket-batsmen
#3
M Habib Noorbhai, Russell C Woolmer, Timothy D Noakes
BACKGROUND: In the current literature, it is questionable whether cricket bats in their current form and dimensions allow a young cricketer to hit the ball effectively. The aim of this study was to test the effectiveness of a novel coaching cricket bat among junior cricket batsmen with regard to enhancing performance and the direction of the backlift. METHODS: A cross-sectional research study with analytical research methods was employed, in which 2 groups (coached: n=12 and uncoached: n=35) of participants (ages 9-13) took part in a pilot and intervention study...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27899447/a-mixed-methods-investigation-of-psychological-factors-relevant-to-weight-maintenance
#4
Amanda Ellen Dibb-Smith, Emily Brindal, Janine Chapman, Manny Noakes
This study investigated perceptions of and engagement with the concepts of planning and problem-solving, within a weight management sample. A total of 53 participants (62% female, 20-74 years old) completed a semi-structured interview and quantitative measures after a 16-week weight maintenance period. Preliminary weight maintainers (who had maintained losses of, at least 10% of their original weight) were compared with heavier-than-baseline participants (who had re-gained more weight than was originally lost)...
November 28, 2016: Journal of Health Psychology
https://www.readbyqxmd.com/read/27897242/cortical-synaptic-and-dendritic-spine-abnormalities-in-a-presymptomatic-tdp-43-model-of-amyotrophic-lateral-sclerosis
#5
Matthew J Fogarty, Paul M Klenowski, John D Lee, Joy R Drieberg-Thompson, Selena E Bartlett, Shyuan T Ngo, Massimo A Hilliard, Mark C Bellingham, Peter G Noakes
Layer V pyramidal neurons (LVPNs) within the motor cortex integrate sensory cues and co-ordinate voluntary control of motor output. In amyotrophic lateral sclerosis (ALS) LVPNs and spinal motor neurons degenerate. The pathogenesis of neural degeneration is unknown in ALS; 10% of cases have a genetic cause, whereas 90% are sporadic, with most of the latter showing TDP-43 inclusions. Clinical and experimental evidence implicate excitotoxicity as a prime aetiological candidate. Using patch clamp and dye-filling techniques in brain slices, combined with high-resolution confocal microscopy, we report increased excitatory synaptic inputs and dendritic spine densities in early presymptomatic mice carrying a TDP-43(Q331K) mutation...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27895165/rats-with-a-missense-mutation-in-atm-display-neuroinflammation-and-neurodegeneration-subsequent-to-accumulation-of-cytosolic-dna-following-unrepaired-dna-damage
#6
Hazel Quek, John Luff, KaGeen Cheung, Sergei Kozlov, Magtouf Gatei, C Soon Lee, Mark C Bellingham, Peter G Noakes, Yi Chieh Lim, Nigel L Barnett, Steven Dingwall, Ernst Wolvetang, Tomoji Mashimo, Tara L Roberts, Martin F Lavin
Mutations in the ataxia-telangiectasia (A-T)-mutated (ATM) gene give rise to the human genetic disorder A-T, characterized by immunodeficiency, cancer predisposition, and neurodegeneration. Whereas a series of animal models recapitulate much of the A-T phenotype, they fail to present with ataxia or neurodegeneration. We describe here the generation of an Atm missense mutant [amino acid change of leucine (L) to proline (P) at position 2262 (L2262P)] rat by intracytoplasmic injection (ICSI) of mutant sperm into oocytes...
November 28, 2016: Journal of Leukocyte Biology
https://www.readbyqxmd.com/read/27876096/a-randomised-controlled-trial-of-the-effects-of-very-low-carbohydrate-and-high-carbohydrate-diets-on-cognitive-performance-in-patients-with-type-2-diabetes
#7
Jeannie Tay, Ian T Zajac, Campbell H Thompson, Natalie D Luscombe-Marsh, Vanessa Danthiir, Manny Noakes, Jonathan D Buckley, Gary A Wittert, Grant D Brinkworth
This study compared the longer-term effects of a very low-carbohydrate, high-fat diet with a high-carbohydrate, low-fat diet on cognitive performance in individuals with type 2 diabetes (T2D). In total, 115 obese adults with T2D (sixty-six males, BMI: 34·6 (sd 4·3) kg/m2, age: 58 (sd 7) years, HbA1c: 7·3 (sd 1·1) %, diabetes duration: 8 (sd 6) years) were randomised to consume either an energy-restricted, very low-carbohydrate, low-saturated-fat (LC) diet or an energy-matched high unrefined carbohydrate, low-fat (HC) diet with supervised aerobic/resistance exercise (60 min, 3 d/week) for 52 weeks...
November 23, 2016: British Journal of Nutrition
https://www.readbyqxmd.com/read/27858977/atypical-presentation-of-livedo-racemosa-in-a-factor-v-leiden-heterozygous-positive-patient-with-pseudomonas-aeruginosa-urosepsis
#8
Jesse Johnston, Rowland Noakes, Kurt Davidson
Impairment of the protein C pathway, detectable by reduced plasma levels of activated protein C (APC), are risk factors for venous thrombosis. Activated protein C maintains clotting homeostasis by regulation of pro-coagulant factors Va and VIIIa. Both infection and the factor V Leiden mutation reduce the formation of APC from protein C in the blood. With low levels of APC, excess factors Va and VIIIa exist, increasing the risk of thrombus formation. Livedo racemosa is characterised by a striking, violaceous branch-like pattering of the skin...
November 12, 2016: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/27824417/-anticoagulation-and-new-therapeutic-options-in-atrial-fibrillation
#9
Karl Mischke
Oral anticoagulation plays an essential role in the treatment of patients with atrial fibrillation as it is indicated for most patients to reduce the risk of stroke. It is prudent to assess the risks of stroke and bleeding using the CHA2DS2-VASc and HAS-BLED scores. Oral anticoagulation is indicated in general for all patients with valvular atrial fibrillation (atrial fibrillation in moderate to severe mitral stenosis or mechanical prosthetic valve) as well as for patients with a CHA2DS2-VASc-Score of 1 - 2 points or higher...
October 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27822154/supplementary-searches-of-pubmed-to-improve-currency-of-medline-and-medline-in-process-searches-via-ovid
#10
Steven Duffy, Shelley de Kock, Kate Misso, Caro Noake, Janine Ross, Lisa Stirk
OBJECTIVE: The research investigated whether conducting a supplementary search of PubMed in addition to the main MEDLINE (Ovid) search for a systematic review is worthwhile and to ascertain whether this PubMed search can be conducted quickly and if it retrieves unique, recently published, and ahead-of-print studies that are subsequently considered for inclusion in the final systematic review. METHODS: Searches of PubMed were conducted after MEDLINE (Ovid) and MEDLINE In-Process (Ovid) searches had been completed for seven recent reviews...
October 2016: Journal of the Medical Library Association: JMLA
https://www.readbyqxmd.com/read/27809233/overconsumption-of-energy-and-excessive-discretionary-food-intake-inflates-dietary-greenhouse-gas-emissions-in-australia
#11
Gilly A Hendrie, Danielle Baird, Brad Ridoutt, Michalis Hadjikakou, Manny Noakes
Population dietary guidelines have started to include information about the environmental impacts of food choices, but more quantifiable evidence is needed, particularly about the impacts associated with discretionary foods. This paper utilised the 2011-2012 Australian Health Survey food intake data along with a highly disaggregated input-output model to estimate the greenhouse gas emissions (GHGe) of Australians' dietary intake, and compare current patterns of eating which vary in diet quality and GHGe to the recommended diet...
October 31, 2016: Nutrients
https://www.readbyqxmd.com/read/27786342/multispectral-imaging-of-organ-viability-during-uterine-transplantation-surgery-in-rabbits-and-sheep
#12
Neil T Clancy, Srdjan Saso, Danail Stoyanov, Vincent Sauvage, David J Corless, Michael Boyd, David E Noakes, Meen-Yau Thum, Sadaf Ghaem-Maghami, James Richard Smith, Daniel S Elson
No abstract text is available yet for this article.
October 1, 2016: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/27623692/immunocap%C3%A2-isac-and-microtest-for-multiplex-allergen-testing-in-people-with-difficult-to-manage-allergic-disease-a-systematic-review-and-cost-analysis
#13
Marie Westwood, Bram Ramaekers, Shona Lang, Nigel Armstrong, Caro Noake, Shelley de Kock, Manuela Joore, Johan Severens, Jos Kleijnen
BACKGROUND: Allergy is a form of immune-mediated exaggerated sensitivity (hypersensitivity) to a substance that is either inhaled, swallowed, injected or comes into contact with the skin. Foreign substances that provoke allergies are called allergens. It has been claimed that multiplex allergen testing may help in diagnosing the cause of symptoms in patients with an unclear cause of allergy or who are allergic to more than one substance. OBJECTIVES: To evaluate multiplex allergen testing [devices that can measure the presence of multiple immunoglobulin E (IgE) antibodies in a patient's blood at the same time], by assessing (1) clinical effectiveness (allergy symptoms, incidence of acute exacerbations, mortality, adverse events of testing and treatment, health-care presentations or admissions, health-related quality of life); (2) effects on treatment (diet, immunotherapy medications, other potential testing); (3) any additional diagnostic information provided by multiplex allergen testing; and (4) cost-effectiveness (cost of different assessment strategies)...
September 2016: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27584019/long-term-effects-of-a-randomised-controlled-trial-comparing-high-protein-or-high-carbohydrate-weight-loss-diets-on-testosterone-shbg-erectile-and-urinary-function-in-overweight-and-obese-men
#14
Lisa J Moran, Grant D Brinkworth, Sean Martin, Thomas P Wycherley, Bronwyn Stuckey, Janna Lutze, Peter M Clifton, Gary A Wittert, Manny Noakes
INTRODUCTION: Obesity is associated with reduced testosterone and worsened erectile and sexual function in men. Weight loss improves these outcomes. High protein diets potentially offer anthropometric and metabolic benefits, but their effects on reproductive and sexual outcomes is not known. AIM: To examine the long-term effects of weight loss with a higher protein or carbohydrate diet on testosterone, sex hormone binding globulin, erectile dysfunction, lower urinary tract symptoms and sexual desire in overweight and obese men...
2016: PloS One
https://www.readbyqxmd.com/read/27555235/chronic-sleep-deprivation-differentially-affects-short-and-long-term-operant-memory-in-aplysia
#15
Harini C Krishnan, Eric J Noakes, Lisa C Lyons
The induction, formation and maintenance of memory represent dynamic processes modulated by multiple factors including the circadian clock and sleep. Chronic sleep restriction has become common in modern society due to occupational and social demands. Given the impact of cognitive impairments associated with sleep deprivation, there is a vital need for a simple animal model in which to study the interactions between chronic sleep deprivation and memory. We used the marine mollusk Aplysia californica, with its simple nervous system, nocturnal sleep pattern and well-characterized learning paradigms, to assess the effects of two chronic sleep restriction paradigms on short-term (STM) and long-term (LTM) associative memory...
October 2016: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/27499396/a-successful-lifestyle-intervention-model-replicated-in-diverse-clinical-settings
#16
Sean Mark, Stefan Du Toit, Timothy D Noakes, Kim Nordli, Douwette Coetzee, Michael Makin, Shani Van der Spuy, Justin Frey, Jay Wortman
Lifestyle interventions can treat metabolic syndrome and prevent type 2 diabetes mellitus, but they remain underutilised in routine practice. In 2010, an LI model was created in a rural primary care practice and spread with few resources to four other rural practices. A retrospective chart review evaluated changes in health indicators in two practice environments by following 372 participants, mainly women (mean age 52 years). Participants had a mean body mass index of 37 kg/m2at baseline and lost an average of 12% of their initial body weight as a result of the intervention...
August 2016: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/27497519/fatty-acid-status-and-antioxidant-defense-system-in-mothers-and-their-newborns-after-salmon-intake-during-late-pregnancy
#17
Cruz E Garcia-Rodriguez, Josune Olza, Maria D Mesa, Concepcion M Aguilera, Elizabeth A Miles, Paul S Noakes, Maria Vlachava, Lefkothea-Stella Kremmyda, Norma D Diaper, Keith M Godfrey, Philip C Calder, Angel Gil
OBJECTIVE: The aim of the present study was to assess the maternal and newborn status of erythrocyte fatty acids and the antioxidant defense system after the intake of two portions of salmon per week during late pregnancy. METHODS: Pregnant women (N = 123) were randomly assigned to continue their habitual diet, which was low in oily fish (control group, n = 61) or to consume two 150-g salmon portions per week (salmon group, n = 62) beginning at 20 wk of gestation and lasting until delivery...
January 2017: Nutrition
https://www.readbyqxmd.com/read/27494448/long-term-effects-of-weight-loss-with-a-very-low-carbohydrate-low-saturated-fat-diet-on-flow-mediated-dilatation-in-patients-with-type-2-diabetes-a-randomised-controlled-trial
#18
Thomas P Wycherley, Campbell H Thompson, Jonathan D Buckley, Natalie D Luscombe-Marsh, Manny Noakes, Gary A Wittert, Grant D Brinkworth
BACKGROUND AND AIMS: Very-low carbohydrate diets can improve glycaemic control in patients with type 2 diabetes (T2DM). However, compared to traditional higher carbohydrate, low fat (HighCHO) diets, they have been associated with impaired endothelial function (measured by flow mediated dilatation [FMD]) that is possibly related to saturated fat. This study aimed to examine the effects of a 12-month hypocaloric very-low carbohydrate, low saturated fat (LowCHO) diet compared to an isocaloric HighCHO diet...
September 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27489220/avian-thermoregulation-in-the-heat-evaporative-cooling-capacity-in-an-archetypal-desert-specialist-burchell-s-sandgrouse-pterocles-burchelli
#19
Andrew E McKechnie, Ben Smit, Maxine C Whitfield, Matthew J Noakes, William A Talbot, Mateo Garcia, Alexander R Gerson, Blair O Wolf
No abstract text is available yet for this article.
August 1, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27488828/marked-changes-in-dendritic-structure-and-spine-density-precede-significant-neuronal-death-in-vulnerable-cortical-pyramidal-neuron-populations-in-the-sod1-g93a-mouse-model-of-amyotrophic-lateral-sclerosis
#20
Matthew J Fogarty, Erica W H Mu, Peter G Noakes, Nickolas A Lavidis, Mark C Bellingham
Amyotrophic lateral sclerosis (ALS) is characterised by the death of upper (corticospinal) and lower motor neurons (MNs) with progressive muscle weakness. This incurable disease is clinically heterogeneous and its aetiology remains unknown. Increased excitability of corticospinal MNs has been observed prior to symptoms in human and rodent studies. Increased excitability has been correlated with structural changes in neuronal dendritic arbors and spines for decades. Here, using a modified Golgi-Cox staining method, we have made the first longitudinal study examining the dendrites of pyramidal neurons from the motor cortex, medial pre-frontal cortex, somatosensory cortex and entorhinal cortex of hSOD1(G93A) (SOD1) mice compared to wild-type (WT) littermate controls at postnatal (P) days 8-15, 28-35, 65-75 and 120...
2016: Acta Neuropathologica Communications
keyword
keyword
101068
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"