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JOURNAL ARTICLE
Bradley M Sugden, Sabine E Grimm, Robert Wolff, Nigel Armstrong, Thomas Otten, Teebah Abu-Zahra, Mark Perry, Mubarak Patel, Jiongyu Chen, Caro Noake, Manuela Joore, Willem J A Witlox
No abstract text is available yet for this article.
May 7, 2024: PharmacoEconomics
#2
JOURNAL ARTICLE
Vikrant Dhurandhar, Nalini Bhola, Mico Chan, Sarah Choi, Tzu-Yun Chung, Bruno Giuffre, Nigel Hunter, Katelyn Lee, Merran McKessar, Ranjani Reddy, Marian Roberts, Christine Shearman, Meredith Kay, Ken Bruderlin, Niko Winarta, Jennifer Noakes
INTRODUCTION: While digital breast tomosynthesis (DBT) has proven to enhance cancer detection and reduce recall rates (RR), its integration into BreastScreen Australia for screening has been limited, in part due to perceived cost implications. This study aims to assess the cost effectiveness of digital mammography (DM) compared with synthesized mammography and DBT (SM + DBT) in a first round screening context for short-term outcomes. METHODS: Clients recalled for nonspecific density (NSD) as a single lesion by both readers at the Northern Sydney Central Coast BreastScreen service in 2019 were included...
May 2, 2024: Journal of Medical Imaging and Radiation Oncology
#3
JOURNAL ARTICLE
Felicity F Noakes, Kirsty L Smitten, Laura E C Maple, Jorge Bernardino de la Serna, Craig C Robertson, Dylan Pritchard, Simon D Fairbanks, Julia A Weinstein, Carl G W Smythe, Jim A Thomas
The biological properties of two water-soluble organic cations based on polypyridyl structures commonly used as ligands for photoactive transition metal complexes designed to interact with biomolecules are investigated. A cytotoxicity screen employing a small panel of cell lines reveals that both cations show cytotoxicity toward cancer cells but show reduced cytotoxicity to noncancerous HEK293 cells with the more extended system being notably more active. Although it is not a singlet oxygen sensitizer, the more active cation also displayed enhanced potency on irradiation with visible light, making it active at nanomolar concentrations...
April 29, 2024: Journal of the American Chemical Society
#4
JOURNAL ARTICLE
Paz Aranega-Bou, Thomas Pottage, Abigail Fenwick, Wilhemina D'Costa, Natalie F Brown, Nicola Yaxley, Marco-Felipe King, Simon T Parker, Daniel Miller, Martín López-García, Catherine J Noakes, Ginny Moore, Allan Bennett
AIMS: To monitor severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) RNA contamination in vehicles operating in England during the pandemic, to better understand transmission risk of SARS-CoV-2 on public transport. METHODS AND RESULTS: We collected 1 314 surface samples between December 2020 and April 2022 on trains and buses managed by five different transport operators. The presence of SARS-CoV-2 RNA was investigated through reverse transcription polymerase chain reaction (RT-PCR)...
April 18, 2024: Journal of Applied Microbiology
#5
JOURNAL ARTICLE
Amy Noakes
No abstract text is available yet for this article.
April 9, 2024: Evidence-based Nursing
#6
Marie Westwood, Nigel Armstrong, Pawel Posadzki, Caro Noake
BACKGROUND: The indication for this assessment is the use of the KardiaMobile six-lead electrocardiogram device for the assessment of QT interval-based cardiac risk in service users prior to the initiation of, or for the monitoring of, antipsychotic medications, which are associated with an established risk of QT interval prolongation. OBJECTIVES: To provide an early value assessment of whether KardiaMobile six-lead has the potential to provide an effective and safe alternative to 12-lead electrocardiogram for initial assessment and monitoring of QT interval-based cardiac risk in people taking antipsychotic medications...
March 2024: Health Technology Assessment: HTA
#7
JOURNAL ARTICLE
Lidia Morawska, Joseph Allen, William Bahnfleth, Belinda Bennett, Philomena M Bluyssen, Atze Boerstra, Giorgio Buonanno, Junji Cao, Stephanie J Dancer, Andres Floto, Francesco Franchimon, Trish Greenhalgh, Charles Haworth, Jaap Hogeling, Christina Isaxon, Jose L Jimenez, Amanda Kennedy, Prashant Kumar, Jarek Kurnitski, Yuguo Li, Marcel Loomans, Guy Marks, Linsey C Marr, Livio Mazzarella, Arsen Krikor Melikov, Shelly L Miller, Donald K Milton, Jason Monty, Peter V Nielsen, Catherine Noakes, Jordan Peccia, Kimberly A Prather, Xavier Querol, Tunga Salthammer, Chandra Sekhar, Olli Seppänen, Shin-Ichi Tanabe, Julian W Tang, Raymond Tellier, Kwok Wai Tham, Pawel Wargocki, Aneta Wierzbicka, Maosheng Yao
If some countries lead by example, standards may increasingly become normalized.
March 29, 2024: Science
#8
Marie Westwood, Bram Ramaekers, Sabine Grimm, Nigel Armstrong, Ben Wijnen, Charlotte Ahmadu, Shelley de Kock, Caro Noake, Manuela Joore
BACKGROUND: Artificial intelligence-derived software technologies have been developed that are intended to facilitate the review of computed tomography brain scans in patients with suspected stroke. OBJECTIVES: To evaluate the clinical and cost-effectiveness of using artificial intelligence-derived software to support review of computed tomography brain scans in acute stroke in the National Health Service setting. METHODS: Twenty-five databases were searched to July 2021...
March 2024: Health Technology Assessment: HTA
#9
JOURNAL ARTICLE
Alexander J Edwards, Marco-Felipe King, Catherine J Noakes, Daniel Peckham, Martín López-García
The Wells-Riley model has been widely used to estimate airborne infection risk, typically from a deterministic point of view (i.e., focusing on the average number of infections) or in terms of a per capita probability of infection. Some of its main limitations relate to considering well-mixed air, steady-state concentration of pathogen in the air, a particular amount of time for the indoor interaction, and that all individuals are homogeneous and behave equally. Here, we revisit the Wells-Riley model, providing a mathematical formalism for its stochastic version, where the number of infected individuals follows a Binomial distribution...
March 19, 2024: Risk Analysis: An Official Publication of the Society for Risk Analysis
#10
JOURNAL ARTICLE
Louise M Burke, Jamie Whitfield
No abstract text is available yet for this article.
April 1, 2024: Medicine and Science in Sports and Exercise
#11
JOURNAL ARTICLE
Alexander J Edwards, Marco-Felipe King, Martín López-García, Daniel Peckham, Catherine J Noakes
BACKGROUND: Many UK hospitals rely heavily on natural ventilation as their main source of airflow in patient wards. This method of ventilation can have cost and energy benefits, but it may lead to unpredictable flow patterns between indoor spaces, potentially leading to the unexpected transport of infectious material to other connecting zones. However, the effects of weather conditions on airborne transmission are often overlooked. METHODS: We proposed a multi-zone CONTAM model of a naturally ventilated hospital respiratory ward, incorporating time-varying weather...
March 4, 2024: Journal of Hospital Infection
#12
JOURNAL ARTICLE
Tim Aung, Rowland Noakes, Kyungho Park
No abstract text is available yet for this article.
2024: Australian Journal of General Practice
#13
JOURNAL ARTICLE
Timothy David Noakes
No abstract text is available yet for this article.
December 11, 2023: Medicine and Science in Sports and Exercise
#14
JOURNAL ARTICLE
Timothy David Noakes
No abstract text is available yet for this article.
December 11, 2023: Medicine and Science in Sports and Exercise
#15
JOURNAL ARTICLE
Carl A Thompson, Amrit Daffu-O'Reilly, Thomas Willis, Adam Gordon, Catherine Noakes, Kishwer Khaliq, Amanda Farrin, Andrew Kemp, Tom Hall, Chris Bojke, Karen Spilsbury
BACKGROUND: Rapid and mass transmission of the SARS-CoV-2 virus amongst vulnerable people led to devastating effects from COVID-19 in care homes. The CONTACT intervention introduced Bluetooth Low Energy 'smart' wearable devices (BLE wearables) as a basis for automated contact tracing in, and feedback on infection risks and patterns to, care homes to try and improve infection prevention and control (IPC). We planned a cluster randomised controlled trial (RCT) of CONTACT. To be feasible, homes had to adopt CONTACT's technology and new ways of working...
December 4, 2023: Implementation science communications
#16
JOURNAL ARTICLE
Shona Brown, Tessa Noakes, Theresa Foster, Larissa Prothero
INTRODUCTION: Menopause is a key workplace issue. Many women will experience symptoms through their later working life. The ambulance service constitutes an employment setting that, dependent on the roles of female staff, can impact on the severity of menopause symptoms and experiences (Prothero et al., 2021). This study aimed to explore female ambulance staff experiences of the menopause transition and suggest ways to improve support offerings. METHODS: A qualitative interpretive approach was adopted, involving 12 UK ambulance services...
December 1, 2023: British paramedic journal
#17
MULTICENTER STUDY
Yusuke Mizuuchi, Kinuko Nagayoshi, Masafumi Nakamura, Hiroki Ikeuchi, Motoi Uchino, Kitaro Futami, Kinya Okamoto, Tsunekazu Mizushima, Hisashi Nagahara, Kazuhiro Watanabe, Koji Okabayashi, Kazutaka Yamada, Hiroki Ohge, Shinji Tanaka, Yoshiki Okita, Yu Sato, Hideki Ueno, Atsuo Maemoto, Michio Itabashi, Hideaki Kimura, Koya Hida, Yusuke Kinugasa, Kenichi Takahashi, Fumikazu Koyama, Tsunekazu Hanai, Kiyoshi Maeda, Toshihiro Noake, Yoshifumi Shimada, Takayuki Yamamoto, Junya Arakaki, Keiji Mastuda, Junji Okuda, Eiji Sunami, Yoshito Akagi, Kenji Kastumata, Kay Uehara, Takeshi Yamada, Shin Sasaki, Soichiro Ishihara, Yoichi Ajioka, Kenichi Sugihara
No abstract text is available yet for this article.
January 3, 2024: British Journal of Surgery
#18
JOURNAL ARTICLE
Bahaa Al-Mhanawi, Marta Boira Marti, Sean D Morrison, Pallavi Gupta, Maath Alani, Peter G Noakes, Ernst J Wolvetang, Mohammed R Shaker
In response to the scarcity of advanced in vitro models dedicated to human CNS white matter research, we present a protocol to generate neuroectoderm-derived embedding-free human brain organoids enriched with oligodendrocytes. We describe steps for neuroectoderm differentiation, development of neural spheroids, and their transferal to Matrigel. We then detail procedures for the development, maturation, and application of oligodendrocyte-enriched brain organoids. The presence of myelin-producing cells makes these organoids useful for studying human white matter diseases, such as leukodystrophy...
November 16, 2023: STAR protocols
#19
JOURNAL ARTICLE
Peter J Cummings, Timothy D Noakes, David M Nichols, Kathleen D Berchou, Maria D Kreher, Paul J Washburn
INTRODUCTION: This article reports the evaluation of a personalized, team-based comprehensive lifestyle modification program targeting known triggers of hyperinsulinemia and insulin resistance. METHODS: A retrospective chart review was undertaken for 536 participants in a novel high-intensity lifestyle behavioral modification program. Surrogate markers of insulin resistance and metabolic syndrome‒related pathologies were measured before and after participation in the the program...
December 2022: AJPM Focus
#20
JOURNAL ARTICLE
M Quintana, A Berger
We explore the critical behavior of dynamic phase transitions in ultrathin uniaxial Co films. Our data demonstrate the occurrence of critical fluctuations, which define the critical regime, and in which we conduct a scaling analysis of the dynamic order parameter Q, utilizing a dynamic analog to the Arrott-Noakes equation of state. Our results show dynamic critical exponents that agree with the 2D Ising model as theoretically predicted. However, equilibrium critical exponents of our sample agree with the 3D Ising model...
September 15, 2023: Physical Review Letters
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