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micro lobectomy

Taiji Kuwata, Kazue Yoneda, Kenichi Kobayashi, Rintarou Oyama, Hiroki Matumiya, Shuichi Shinohara, Masaru Takenaka, Soichi Oka, Yasuhiro Chikaishi, Naoko Inanishi, Koji Kuroda, Fumihiro Tanaka
BACKGROUND Circulating tumor cells (CTCs) are tumor cells that are shed from primary tumors and circulate in the peripheral blood. CTCs, as a surrogate of micro-metastasis, can be a useful clinical marker, but their clinical significance remains unclear in lung cancer. We now report a case of lung cancer in which the count of CTCs was useful in monitoring postoperative recurrence. CASE REPORT A 50-year-old man had undergone right upper lobectomy for lung cancer (pT1bN2M0, stage IIIA adenocarcinoma), followed by cisplatin-based adjuvant chemotherapy...
2016: American Journal of Case Reports
Paolo Del Rio, Chiara Montana Montana, Giulia Mingardi, Giovanna Piva, Mario Sianesi, Luigi Corcione
BACKGROUND: The incidence of thyroid carcinoma goes from 0.5 to 10 cases on 100.000, depending on the country, the context and purpose of the study. The high incidence of differentiated thyroid tumor is continuously growing. While most malignant pathologies affect the adults, a proportion of 1-2 % of paediatric population is affected by solitary nodule, of which some are malignant cancers. Studying thyroid malignant cancer, the most sensitive and accurate imaging technique is the colorDoppler ultrasounds...
September 2, 2016: Minerva Endocrinologica
S Périé, F Torti, M Lefevre, N Chabbert-Buffet, A Jafari, J Lacau St Guily
OBJECTIVES: To quantify and discuss the prevalence of unsuspected thyroid lymph node metastases discovered in specimens from neck dissection for head and neck squamous cell carcinoma (HNSCC) and discuss the impact on patient management. STUDY DESIGN: Retrospective study between May 2004 and January 2007. SETTING: University hospital. METHODS: Pathological analysis of cervical lymph node dissection performed during surgery for HNSCC in a total of 349 neck dissections in 266 consecutive patients...
July 26, 2016: European Annals of Otorhinolaryngology, Head and Neck Diseases
Shi Yan, Xing Wang, Chao Lv, Kevin Phan, Yuzhao Wang, Jia Wang, Yue Yang, Nan Wu
BACKGROUND: Postoperative pleural drainage markedly influences the length of postoperative stay and financial costs of medical care. The aim of this study is to retrospectively investigate potentially predisposing factors related to pleural drainage after curative thoracic surgery and to explore the impact of mediastinal micro-vessels clipping on pleural drainage control after lymph node dissection. METHODS: From February 2012 to November 2013, 322 consecutive cases of operable non-small cell lung cancers (NSCLC) undergoing lobectomy and mediastinal lymph node dissection with or without application of clipping were collected...
March 2016: Journal of Thoracic Disease
Ying Zhou, Yunyuan Li, Li Fan, Shiyuan Liu
During a thoracic computed tomography (CT) scan, a 36-year-old male was diagnosed with a solitary oval pulmonary mixed ground-glass nodule in the right upper lobe of the lung. The edge of the nodule was well-defined, and its largest axial size was approximately 1.1 × 0.9 cm(2). This nodule was slightly lobulated, but not obviously speculated. Solid components, micro-cystic lucency shadow, small high-density rings and tiny vascular branches were all visible in the nodule. During hospitalization, a technetium 99 m methylene diphosphonate (Tc-99 m MDP) bone scan was performed, which showed a skeletal foci with abnormal uptake in the left iliac...
2015: International Journal of Clinical and Experimental Pathology
Jinbai Miao, Shengcai Hou, Xiaoxing Hu, Tong Li, Bin Hu, Hui Li
OBJECTIVE: To investigate the relationship of the preoperative HRCT, postoperative pathological subtype and EGFR gene mutation types in the patients of small peripheral lung adenocacinoma confirmed by operation. METHODS: Between December 2011 and November 2014, Ninety-four invasive adenocarcinoma patient were selected from 156 patients with pulmonary nodule underwent operation in Beijing Chaoyang hospital. Among them, there were male 37 cases, female 57 cases, age range from 32 to 76, mean age 52...
September 1, 2015: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Pinar Yazici, Mehmet Mihmanli, Emre Bozdag, Nurcihan Aygun, Mehmet Uludag
OBJECTIVE: The relationship between primary hyperparathyroidism (pHPT) and papillary thyroid cancer (PTC) still remains unclear. We aimed to investigate the incidence of the co-existence of pHPT and PTC. MATERIALS AND METHODS: Between 2010 and 2013, all patients with pHPT were retrospectively reviewed and those undergoing concomitant thyroid surgery were recorded. Of these, patients with a pathological result showing papillary or micro-papillary thyroid cancer were included into the study...
October 2015: Eurasian Journal of Medicine
G Donatini, M Castagnet, T Desurmont, N Rudolph, D Othman, J L Kraimps
BACKGROUND: Total thyroidectomy is a well-established surgical approach for the management of papillary thyroid cancer (PTC). However, the best surgical approach for papillary microcarcinoma is nowadays still debated. Both total thyroidectomy and simple lobectomy are used. We report the experience of a single University center in the treatment of thyroid microcarcinoma. METHODS: A retrospective analysis on all patients who underwent thyroid surgery at our institution over a 24-year period (1991-2015) was performed...
March 2016: World Journal of Surgery
Kutlay Karaman, A Murat Dokdok, Oktay Karadeniz, Cemile Ceylan, Kayıhan Engin
OBJECTIVE: To present our experience with placing endovascular coils in pulmonary arteries used as a fiducial marker for CyberKnife therapy and to describe the technical details and complications of the procedure. MATERIALS AND METHODS: Between June 2005 and September 2013, 163 patients with primary or secondary lung malignancies, referred for fiducial placement for stereotactic radiosurgery, were retrospectively reviewed. Fourteen patients (9 men, 5 women; mean age, 70 years) with a history of pneumonectomy (n = 3), lobectomy (n = 3) or with severe cardiopulmonary co-morbidity (n = 8) underwent coil (fiducial marker) placement...
May 2015: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
De-Guang Zhang, Li Gao, Yu-Wen Miao, Gao-Fei He, Lei Xie
OBJECTIVES: To identify the risk factors for posterior right recurrent laryngeal nerve lymph node metastasis (PRRLN-LNM) in papillary thyroid carcinoma (PTC). METHODS: We conducted a retrospective study of 389 patients with primary PTC who underwent right lobectomy or total thyroidectomy, and comprehensive right or bilateral central compartment dissection (CCD) with or without lateral neck dissection (LND) between January 2010 and May 2013 at the Department of Head and Neck Surgery, Institute of Micro-Invasive Surgery of Zhejiang University, Zhejiang, China...
August 2014: Saudi Medical Journal
Moon-Young Kim, Chang Hyun Kang, Sung-Hye Park
AIMS: Congenital pulmonary airway malformation (CPAM) is a rare developmental anomaly of the lung. Here, we report a case of mucinous adenocarcinoma arising in CPAM. A 23-month-old boy underwent a thoracoscopic lobectomy of the left upper lobe of the lung based on a presumptive diagnosis of asymptomatic CPAM, found in antenatal sonogram. METHODS AND RESULTS: Histologically, the lesion was consistent with CPAM, Stocker type I. In addition, multiple foci ranging from mucinous epithelial hyperplasia to mucinous adenocarcinoma were detected...
December 2014: Histopathology
P Miccoli, F Basolo
BACKGROUND: BRAF mutation is probably the only molecular marker acting as a risk factor that is available before surgery: for this reason, soon after it became quite widespread, it seemed an important tool as a guide towards an individualized surgical therapy in papillary thyroid carcinoma. PURPOSE: Capsule invasion, multifocality, and lymph node involvement are the most important parameters influencing the choice of surgical strategy in front of small papillary cancers and, in more detail, of micro papillary carcinomas...
February 2014: Langenbeck's Archives of Surgery
Syed Quadri, Santiago Miro, Karl Uy, Geoffrey Graeber
SESSION TYPE: Thoracic Surgery IPRESENTED ON: Monday, October 22, 2012 at 11:15 AM - 12:30 PMPURPOSE: We report our experiences with a previously described, but underutilized, technique for minimally invasive localization and surgical excision biopsy of small lung nodules-micro-coil guided video-assisted thoracoscopic (MC-VATS) lung resection. Accurate diagnosis of small intrapulmonary lung nodules (0.5-2.0 cm) is a challenge. It can be difficult to reliably biopsy these under CT guidance. Even minimally invasive surgical techniques are difficult, as these nodules often cannot be localized unless the surgeon converts to open thoracotomy to palpate the lung...
October 1, 2012: Chest
Makio Hayama, Masayuki Chida, Yoko Karube, Motohiko Tamura, Satoru Kobayashi, Takeshi Oyaizu, Koichi Honma
OBJECTIVE: Intraoperative diagnosis of lymph node (LN) metastasis is critical in lung cancer patients. The one-step nucleic acid amplification (OSNA) assay is a novel technique using a loop-mediated isothermal amplification method of gene amplification. The objective of this study was to investigate whether the OSNA assay provides sufficient diagnosis of LN metastasis in lung cancer patients. METHODS: A total of 40 LN stations were dissected from the 20 patients, who had curative lobectomy for lung cancer...
2014: Annals of Thoracic and Cardiovascular Surgery
Pierre Bonnette
It has been proved that lobectomy for lung cancer of less than 3 cm is superior to sublobar resection (segmentectomy and wedge resection) in the Lung Cancer Study Group trial published in 1995. Lobectomy is therefore recommended, with lymph node resection. Nevertheless, some publications have shown identical or close results after segmentectomy for tumors of less than 2 cm, and after wedge resection for tumors of less than 1 cm. It is likely that local recurrences are avoided by respecting a macroscopic margin of more than 2 cm around the tumor...
November 2012: Bulletin du Cancer
Haggi Mazeh, Yair Levy, Ido Mizrahi, Liat Appelbaum, Nadia Ilyayev, David Halle, Herbert R Freund, Aviram Nissan
BACKGROUND: Fine needle aspiration biopsy (FNAB) is the most commonly used diagnostic tool to differentiate benign from malignant thyroid nodules. Nevertheless, some FNAB cytology results are not definite. In such cases diagnostic thyroid lobectomy is performed with malignancy rate on final histopathology ranging at 15%-75%. The aim of this study was to improve on the accuracy of FNAB-based cytology by amplification of microRNAs (micro ribonucleic acids [miRs]) from the residual cells left in the FNAB needle after submission for cytology...
April 2013: Journal of Surgical Research
Erica Stocco, Maria Rosa Pelizzo, Gaia Grassetto, Costantino Pagetta, Daniela Larizza, Arianna Massaro, Maria Cristina Marzola, Domenico Rubello
We report here a case of a paediatric hyperthyroidism due to a micro-macro-follicular thyroid adenoma in the presence of heterozygous point mutation of TSH receptor (TSHr). We describe the case from the initial diagnosis, through laboratoristic examinations and imaging techniques, until the radical surgical treatment made by a mini-cervicotomic videoassisted technique. We also explained the genetic work-up from peripheral blood and thyroid adenoma tissue.
June 2012: Annales D'endocrinologie
M R Diaconescu, M Glod, M Grigorovici, S Diaconescu
UNLABELLED: The aim of this report is to describe a fortuitely discovered association between parathyromatosis and papillary thyroid microcarcinoma. CASE DESCRIPTION: A 56-year-old woman presented with a pyelic relapsed stone, bone pains, neurovegetative com-plaints and iPTH = 348 ng/l as manifestations of recurrent primary hyperparathyroidism after a right inferior parathyroid adenoma exeresis done elsewere six years ago. Ultrasonography showed a 5 mm hypoechoic zone at the lower pole of the right lobe of the thyroid...
September 2011: Chirurgia
Venu G Pillarisetty, Steven C Katz, Ronald A Ghossein, R Michael Tuttle, Ashok R Shaha
BACKGROUND: The aggressive nature of medullary thyroid cancer (MTC) is evidenced by its propensity to present early with lymph node (LN) metastases. The clinical significance of sporadic MTC < or =1 cm (micro-MTC) is not clearly defined. METHODS: We performed a retrospective review of the clinical, laboratory, and pathologic data for all patients treated or followed at our institution for sporadic micro-MTC from 1987 through 2008. RESULTS: A total of 18 patients met the criteria for inclusion in our study...
October 2009: Annals of Surgical Oncology
Shinichi Suzuki, Toshihiko Fukushima, Seiichi Takenoshita
Well differentiated thyroid carcinoma (WDTC) consists of papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC). Although both cancers are excellent prognosis, there are different in carcinogenesis by some genes, criteria of pathological diagnosis and transforming pattern between PTC and FTC. So the strategy for surgical treatment of them should be discussed separately. The patient with PTC less than 45 years old whose tumor is localized in a unilateral lobe without extra thyroidal invasion, lymph node metastasis and distant metastasis should be performed a unilateral lobectomy with central node dissection (D1)...
November 2007: Nihon Rinsho. Japanese Journal of Clinical Medicine
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