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JOURNAL ARTICLE
Paolo Spinnato, Giuseppe Bianchi
No abstract text is available yet for this article.
February 28, 2024: AJR. American Journal of Roentgenology
#22
JOURNAL ARTICLE
Satoshi Nitta, Shuya Kandori, Reo Takahashi, Shuhei Suzuki, Kazuki Hamada, Kozaburo Tanuma, Masanobu Shiga, Kosuke Kojo, Shotaro Sakka, Yoshiyuki Nagumo, Akio Hoshi, Bryan J Mathis, Hiromitsu Negoro, Ayako Okuyama, Takahiro Higashi, Hiroyuki Nishiyama
OBJECTIVES: We sought clinical characteristics, survival outcomes, and prognostic factors for overall survival of retroperitoneal sarcoma in Japan. METHODS: A Japanese hospital-based cancer registry database with a pivotal 10-year follow-up was used to identify and enroll patients, registered from 106 institutions, diagnosed with retroperitoneal sarcoma in 2008-2009. Treating hospitals were divided by hospital care volume; high-volume hospitals and low-volume hospitals were defined as ≥ 4 and < 4 cases/year, respectively...
February 26, 2024: Japanese Journal of Clinical Oncology
#23
JOURNAL ARTICLE
Sreenija Yarlagadda, Tugce Kutuk, Ramon E Jimenez, Muni B Rubens, Matthew Hall, Nicole T Eiseler, Noah S Kalman
PURPOSE: Retroperitoneal sarcomas (RPS) have varied treatment practices with regard to the use of radiation therapy (RT). Preoperative RT ∼50 Gy is commonly used, but the Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma (STRASS-1) randomized trial demonstrated no improvement in abdominal recurrence-free survival with preoperative RT. Dose escalation has been proposed to improve the efficacy of preoperative RT. We analyzed RPS treated with preoperative intensity modulated proton therapy (IMPT) to an escalated dose of 63 Gy at a single institution...
April 2024: Advances in Radiation Oncology
#24
JOURNAL ARTICLE
Kyla M Walter, William T N Culp, Michelle A Giuffrida, Pierre Amsellem, Mandy L Wallace, Janet A Grimes, Brandan Wustefeld-Janssens, Meaghan O'Neill, Sita S Withers, Dylan Shannon, Janis Lapsley, Joanne Tuohy, Haleigh Hixson, Cassie N Lux, Brad Matz, Laura E Selmic, Alysha McGrath, Maureen A Griffin, Philipp D Mayhew, Michele A Steffey, Ingrid M Balsa, Robert B Rebhun, Michael S Kent
OBJECTIVE: To report the clinical characteristics, treatments, and outcomes in a cohort of dogs with histologically confirmed retroperitoneal sarcoma (RPS) and to identify potential variables of prognostic significance. ANIMALS: 46 client-owned dogs from 10 clinics with histopathologic diagnosis of a sarcoma originating from the retroperitoneal space. METHODS: Medical records were retrospectively reviewed to obtain information regarding clinical characteristics, treatments, and outcomes...
February 21, 2024: Journal of the American Veterinary Medical Association
#25
JOURNAL ARTICLE
Manuel Ramanovic, Marko Novak, Andraz Perhavec, Taja Jordan, Karteek Popuri, Nada Rotovnik Kozjek
BACKGROUND: Retroperitoneal sarcomas (RPS) are rare tumours of mesenchymal origin, commonly presented as a large tumour mass at time of diagnosis. We investigated the impact of body composition on outcome in patients operated on for primary localized RPS. PATIENTS AND METHODS: We retrospectively analysed data for all patients operated on for primary RPS at our institution between 1999 and 2020. Preoperative skeletal muscle area (SMA), visceral and subcutaneous adipose tissue area (VAT and SAT) and muscle radiation attenuation (MRA) were calculated using computed tomography scans at the level of third lumbar vertebra...
March 1, 2024: Radiology and Oncology
#26
JOURNAL ARTICLE
Ranjana Giri, Saroj Ranjan Sahu, Sabyasachi Parida, Subrat Kumar Sahu
A 57-year-old male had abdominal pain and distension for 6-7 months with a palpable swelling in the right lumbar region. Contrast-enhanced computed tomography abdomen showed a large heterogeneous lesion with fat density measuring 22 cm ´ 16.5 cm in the right suprarenal region. Laparotomy was done which showed an encapsulated mass measuring 21 cm ´ 14 cm ´ 5 cm. Cut section revealed yellowish areas admixed with hemorrhage and large areas of necrosis. Microscopy revealed adrenal myelolipoma. The patient was found to have sickling positive...
October 1, 2023: Journal of Cancer Research and Therapeutics
#27
JOURNAL ARTICLE
Nada Shaker, Hans Iwenofu, Nuha Shaker, Zofia Tynski, Omar P Sangueza, Abdul Abid
BACKGROUND: Myxoid neurofibromas (NF) are uncommon, benign spindle cell tumors that originate from peripheral nerve sheaths, often posing a diagnostic challenge due to their hypocellularity on cytology specimens. Distinguishing myxoid spindle cell lesions can be challenging, given the broad range of potential differential diagnoses. CASE PRESENTATION: A 26-year-old female with a past medical history of embolized inguinal, flank, and retroperitoneal venolymphatic malformation presented with a left pelvic pain causing significant disability...
February 16, 2024: Diagnostic Cytopathology
#28
Claudio Lodoli, Miriam Attalla El Halabieh, Francesco Santullo, Carlo Abatini, Valerio Gallotta, Fabio Pacelli
INTRODUCTION: Radical surgical resection with negative margins is the mainstay of treatment for retroperitoneal vascular leiomyosarcomas. Given the retroperitoneal location of these tumors, open surgery is, historically, the chosen surgical approach, however, it is burdened with high postoperative morbidity. In selected cases, the small dimension of the tumor and a favorable location, allow to perform a minimally invasive treatment. PRESENTATION OF CASE: A 67-year-old female patient with a diagnosis of a leiomyosarcoma arising from the left renal vein underwent a robotic resection of the left renal vein with preservation of the left kidney and a relative outflow trough the gonadal vessels...
February 14, 2024: International Journal of Surgery Case Reports
#29
Jianhong Yan, Qi Wu, Yuchang Hu, Ting Nai
Follicular dendritic cell sarcoma (FDCS) is a rare tumor, which mainly originates from follicular dendritic cells (FDCs) in the lymph nodes. Sometimes FDCS can arise from outside the lymph nodes. FDCS is an extremely rare malignant tumor in intraperitoneal or retroperitoneal tissue. We gathered the detailed clinical data of three patients diagnosed with FDCS in the abdomen. The clinical observations and histopathologic and immunohistochemical features of FDCS were analyzed. The patients included two men and one woman aged 55 ~ 61 years old...
2024: Indian Journal of Pathology & Microbiology
#30
JOURNAL ARTICLE
Christina L Roland, Elise F Nassif Haddad, Emily Z Keung, Wei-Lien Wang, Alexander J Lazar, Heather Lin, Manoj Chelvanambi, Edwin R Parra, Khalida Wani, B Ashleigh Guadagnolo, Andrew J Bishop, Elizabeth M Burton, Kelly K Hunt, Keila E Torres, Barry W Feig, Christopher P Scally, Valerae O Lewis, Justin E Bird, Ravin Ratan, Dejka Araujo, M Alexandra Zarzour, Shreyaskumar Patel, Robert Benjamin, Anthony P Conley, J Andrew Livingston, Vinod Ravi, Hussein A Tawbi, Patrick P Lin, Bryan S Moon, Robert L Satcher, Bilal Mujtaba, Russell G Witt, Raymond S Traweek, Brandon Cope, Rossana Lazcano, Chia-Chin Wu, Xiao Zhou, Mohammad M Mohammad, Randy A Chu, Jianhua Zhang, Ashish Damania, Pranoti Sahasrabhojane, Taylor Tate, Kate Callahan, Sa Nguyen, Davis Ingram, Rohini Morey, Shadarra Crosby, Grace Mathew, Sheila Duncan, Cibelle F Lima, Jean-Yves Blay, Wolf Herman Fridman, Kenna Shaw, Ignacio Wistuba, Andrew Futreal, Nadim Ajami, Jennifer A Wargo, Neeta Somaiah
Based on the demonstrated clinical activity of immune-checkpoint blockade (ICB) in advanced dedifferentiated liposarcoma (DDLPS) and undifferentiated pleomorphic sarcoma (UPS), we conducted a randomized, non-comparative phase 2 trial ( NCT03307616 ) of neoadjuvant nivolumab or nivolumab/ipilimumab in patients with resectable retroperitoneal DDLPS (n = 17) and extremity/truncal UPS (+ concurrent nivolumab/radiation therapy; n = 10). The primary end point of pathologic response (percent hyalinization) was a median of 8...
February 13, 2024: Nature Cancer
#31
JOURNAL ARTICLE
Leva Gorji, Melica Nikahd, Amblessed Onuma, Diamantis Tsilimigras, J Madison Hyer, Samantha Ruff, Farhan Z Ilyas, Carlo Contreras, Valerie P Grignol, Alex Kim, Raphael Pollock, Timothy M Pawlik, Joal D Beane
BACKGROUND: Multivisceral resection of retroperitoneal liposarcoma (LPS) is associated with increased morbidity and may not confer a survival benefit compared with tumor-only (TO) resection. We compared both approaches using a novel statistical method called the "win ratio" (WR). METHODS: Patients who underwent resection of LPS from 2004 to 2015 were identified from the National Cancer Database. Multivisceral resection was defined as removal of the primary site in addition to other organs...
February 12, 2024: Annals of Surgical Oncology
#32
JOURNAL ARTICLE
Yoko Saito, Tetsuya Shindo, Ko Kobayashi, Kohei Hashimoto, Yuki Kyoda, Takeshi Maehana, Toshiaki Tanaka, Yohei Arihara, Kazuyuki Murase, Kohichi Takada, Naoya Masumori
We experienced two cases of renal primary synovial sarcoma. Case 1: A 29-year-old man underwent laparoscopic radical nephrectomy and was originally diagnosed with renal cell carcinoma. Case 2: A 25-year-old man was treated by open radical nephrectomy since radiographical findings indicated tumor invasion to the ureter causing hydronephrosis. Both cases were pathologically diagnosed as renal synovial sarcomas, and were followed using computed tomography. Recurrence was observed within a year in both cases.
January 2024: Hinyokika Kiyo. Acta Urologica Japonica
#33
JOURNAL ARTICLE
Jens Jakob, Christoph Reissfelder
No abstract text is available yet for this article.
February 6, 2024: Chirurgie (Heidelb)
#34
Peter Bael, Bayan Alqtishat, Khaled Alshawwa
We present a case series of three successfully resected tumors in our center at Al-Makassed Hospital in Jerusalem, Palestine, all of which primarily involved or invaded adjacent structures and needed a multidisciplinary approach to achieve R0 resection. Our first patient is a 42-year-old previously healthy female with intermittent attacks of dull aching abdominal pain. Her tumor was a leiomyosarcoma that involved major vessels and other adjacent vital structures. Ultimately, she needed major highly advanced surgery necessitating the need for vascular reconstruction of the IVC, as well as R0 resection...
2024: Frontiers in Surgery
#35
Makishi Nakamura, Kazuaki Yamanaka, Taigo Kato, Koji Hatano, Yoichi Kakuta, Atsunari Kawashima, Shinichiro Fukuhara, Norio Nonomura
A 52-year-old male had pain in the right back and right hypochondrium, and an abdominal CT scan revealed a 49-mm tumor in the right upper perirenal space. Additional MRI and PET-CT suggested that the tumor may be a primary adrenal carcinoma and could invade the liver and diaphragmatic leg. The tumor was completely removed by laparotomy and histopathologically diagnosed as retroperitoneal primary undifferentiated pleomorphic sarcoma. The patient has remained recurrence-free for 1.5 years after the surgery.
March 2024: Urology Case Reports
#36
REVIEW
Yukinori Yamagata, Motokiyo Komiyama, Shintaro Iwata
Retroperitoneal sarcoma (RPS) is a rare tumor classified into many histological types. It is also often detected only after it has grown to a considerable size and requires extensive resection of the surrounding organs, making it difficult to offer optimal patient-tailored management. Evidence supporting specific treatment modalities for RPS is insufficient, owing to its rarity. The Japanese clinical practice guidelines for RPS were published in December 2021, with the aim of accumulating existing evidence and indicating the optimal practice for RPS...
January 2024: Annals of Gastroenterological Surgery
#37
Patrycja Sosnowska-Sienkiewicz, Przemysław Mańkowski, Honorata Stadnik, Agata Dłubak, Anna Czekała, Marek Karczewski
INTRODUCTION: Liposarcomas are the most common of all sarcomas. A well-differentiated liposarcoma can transform into a dedifferentiated liposarcoma with myogenic, osteo- or chondrosarcomatous heterologous differentiation. Genomic amplification of MDM2 gene is then characteristic. Treatment usually involves surgical resection to radically remove the tumor. Other treatments such as chemotherapy and radiotherapy may also be used. CASE REPORT: A 60-year-old patient was admitted to the hospital for surgical treatment of a left renal mass...
December 25, 2023: Diseases (Basel)
#38
Eduardo Alfredo González Murillo, Eduardo Benavides Salas, María Margarita Vizcaino Lozano
Teratomas are neoplasms originate from germ cells and can undergo malignant transformation, the World Health Organization (WHO) classified them as teratoma with somatic-type malignancy which is uncommon and sarcomas are the histological type with the highest incidence. It is important to identify this type of tumors because influences the prognosis and survival of the patient. We present the case of a 5-month-old male, who began his condition at one month-old with constipation and increase of the abdominal circumference, imaging studies revealed an abdominal lesion, he was treated with chemotherapy and surgery...
2024: Revista Española de Patología
#39
Amanda E Sion, Josh Palka, Sarah Martin, Rafic Beydoun, Conrad Maitland
The objective of this case report is to describe a rare case of primary follicular dendritic cell sarcoma (FDCS) of the kidney. FDCS is a rare soft tissue malignancy that most often presents intranodally with lymphadenopathy of the neck, mediastinum, and axilla. One-third of cases present extranodally and most commonly affect the liver, lung, and tonsils. To date, there have been few reports of retroperitoneal FDCS and, to the best of our knowledge, only two other reported cases with primary renal involvement...
December 2023: Curēus
#40
Prateek S Harne, Ujjwal Soni, Ans Albustamy, Arturo Suplee Rivera, Asif Zamir
This case report highlights the challenge of differentiating between immunoglobulin G4 (IgG4)-related disease (IGRD) and liposarcoma, which have similar symptoms and serological markers. A 40-year-old woman presented with right upper-quadrant pain and a retroperitoneal mass. Initial biopsy indicated increased IgG4-positive cells, leading to an IGRD diagnosis. However, the mass grew, despite prednisone treatment, prompting a repeat biopsy that revealed well-differentiated liposarcoma. Liposarcoma should be considered in patients with retroperitoneal masses and elevated IgG4 levels...
January 2024: ACG Case Reports Journal
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