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https://www.readbyqxmd.com/read/28437836/nurses-attitudes-toward-the-single-checking-of-medications
#1
Rachel Cross, Paul N Bennett, Cherene Ockerby, Wei Chun Wang, Judy Currey
BACKGROUND AND AIM: The policy of single over double checking of medications has been adopted by many health services; however, nurses' attitudes toward single-checking medications remains unclear. The aim of this study was to explore the attitudes of nurses who single check and administer medications in a setting where single checking has been in place for over a decade. METHODS: A cross-sectional survey design using the validated Single Checking Administration Medication Scale-II to registered nurses (n = 299) working in one metropolitan teaching hospital in Victoria, Australia...
April 24, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28437688/application-of-near-infrared-spectroscopy-for-the-rapid-quality-assessment-of-radix-paeoniae-rubra
#2
Hao Zhan, Jing Fang, Liying Tang, Hongjun Yang, Hua Li, Zhuju Wang, Bin Yang, Hongwei Wu, Meihong Fu
Near-infrared (NIR) spectroscopy with multivariate analysis was used to quantify gallic acid, catechin, albiflorin, and paeoniflorin in Radix Paeoniae Rubra, and the feasibility to classify the samples originating from different areas was investigated. A new high-performance liquid chromatography method was developed and validated to analyze gallic acid, catechin, albiflorin, and paeoniflorin in Radix Paeoniae Rubra as the reference. Partial least squares (PLS), principal component regression (PCR), and stepwise multivariate linear regression (SMLR) were performed to calibrate the regression model...
April 20, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28437156/development-of-a-taqman-based-real-time-pcr-assay-for-rapid-and-specific-detection-of-fowl-aviadenovirus-serotype-4
#3
Jianchang Wang, Jinfeng Wang, Ping Chen, Libing Liu, Wanzhe Yuan
Twelve serotypes of fowl aviadenovirus, namely, FAdV-(1-8a and 8b-11), have been identified, among which FAdV-4 is the aetiologic agent of hepatitis hydropericardium syndrome (HHS) in chickens. Outbreaks of HHS have been documented in many countries, causing significant economic losses. Real-time PCR methods described so far in the literature cross-detect different serotypes of FAdVs. In this study, we aimed to develop a TaqMan-based real-time PCR assay for the specific detection of FAdV-4. A pair of primers targeting the hexon gene and a TaqMan probe were designed...
June 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28436849/reverse-classification-accuracy-predicting-segmentation-performance-in-the-absence-of-ground-truth
#4
Vanya V Valindria, Ioannis Lavdas, Wenjia Bai, Konstantinos Kamnitsas, Eric O Aboagye, Andrea G Rockall, Daniel Rueckert, Ben Glocker
When integrating computational tools such as automatic segmentation into clinical practice, it is of utmost importance to be able to assess the level of accuracy on new data, and in particular, to detect when an automatic method fails. However, this is difficult to achieve due to absence of ground truth. Segmentation accuracy on clinical data might be different from what is found through cross-validation because validation data is often used during incremental method development, which can lead to overfitting and unrealistic performance expectations...
April 17, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28436753/prevalence-and-differences-between-type-1-and-type-2-diabetes-mellitus-regarding-female-sexual-dysfunction-a-cross-sectional-egyptian-study
#5
Magdy R Ahmed, Mohamed M Shaaban, Wael F Sedik, Tamer Y Mohamed
OBJECTIVE: To evaluate the female sexual dysfunction in both type 1 and type 2 diabetes mellitus (DM). METHODS: This cross-sectional study was carried out at Suez Canal University Hospitals from the start of February 2015 to the end of May 2016 among 189 married premenopausal women attending endocrinology and diabetology outpatient clinic for regular follow-up; 25 of whom refused to participate and 18 more were excluded due to incomplete data sets resulting in a final sample of 146 diabetic females...
April 24, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28436410/a-new-approach-to-develop-computer-aided-diagnosis-scheme-of-breast-mass-classification-using-deep-learning-technology
#6
Yuchen Qiu, Shiju Yan, Rohith Reddy Gundreddy, Yunzhi Wang, Samuel Cheng, Hong Liu, Bin Zheng
PURPOSE: To develop and test a deep learning based computer-aided diagnosis (CAD) scheme of mammograms for classifying between malignant and benign masses. METHODS: An image dataset involving 560 regions of interest (ROIs) extracted from digital mammograms was used. After down-sampling each ROI from 512×512 to 64×64 pixel size, we applied an 8 layer deep learning network that involves 3 pairs of convolution-max-pooling layers for automatic feature extraction and a multiple layer perceptron (MLP) classifier for feature categorization to process ROIs...
April 18, 2017: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/28436405/a-comparison-of-methods-for-three-class-mammograms-classification
#7
Marina Milosevic, Zeljko Jovanovic, Dragan Jankovic
BACKGROUND: Mammography is considered the gold standard for early breast cancer detection but it is very difficult to interpret mammograms for many reason. Computer aided diagnosis (CAD) is an important development that may help to improve the performance in breast cancer detection. OBJECTIVE: We present a CAD system based on feature extraction techniques for detecting abnormal patterns in digital mammograms. METHODS: Computed features based on gray-level co-occurrence matrices (GLCM) are used to evaluate the effectiveness of textural information possessed by mass regions...
April 14, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/28436032/application-of-maldi-tof-ms-for-estimating-the-postmortem-interval-in-rat-muscle-samples
#8
Chengzhi Li, Dong Ma, Kaifei Deng, Yijiu Chen, Ping Huang, Zhenyuan Wang
Estimating the postmortem interval (PMI) is very important in the forensic sciences. Although many approaches have been used for estimating the PMI, accurate PMI calculations are still difficult. In this study, four Sprague Dawley (SD) rats were sacrificed by suffocation, and muscle samples were collected by dissection at various time intervals (0, 48, 96, and 144 h) after death. All samples were probed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) to obtain molecular images and data for principal component analysis (PCA)...
April 23, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28435894/oral-bacterial-acid-base-metabolism-in-caries-screening-a-proof-of-concept-study
#9
E Morou-Bermudez, M A Loza-Herrero, V Garcia-Rivas, E Suarez-Perez, R J Billings
The objective of this cross-sectional study was to clinically validate an array of biochemical tests for oral acid/alkali generation as caries screening instruments. 185 adult subjects (mean 33.6±10.6 years) were examined clinically for dental caries using the ICDAS criteria. Bitewing radiographs were used to confirm interproximal surfaces of posterior teeth. For the purposes of this study, subjects were classified as "caries-active" if they had at least one untreated caries lesion with ICDAS 4 or higher. Pooled supragingival plaque and unstimulated saliva samples were collected and assayed for pH changes from sucrose and urea metabolism using colorimetric tests...
April 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28435097/defining-the-most-probable-location-of-the-parahippocampal-place-area-using-cortex-based-alignment-and-cross-validation
#10
REVIEW
Kevin S Weiner, Michael Barnett, Nathan Witthoft, Golijeh Golarai, Anthony Stigliani, Kendrick N Kay, Jesse Gomez, Vaidehi S Natu, Katrin Amunts, Karl Zilles, Kalanit Grill-Spector
The parahippocampal place area (PPA) is a widely studied high-level visual region in the human brain involved in place and scene processing. The goal of the present study was to identify the most probable location of place-selective voxels in medial ventral temporal cortex. To achieve this goal, we first used cortex-based alignment (CBA) to create a probabilistic place-selective region of interest (ROI) from one group of 12 participants. We then tested how well this ROI could predict place selectivity in each hemisphere within a new group of 12 participants...
April 18, 2017: NeuroImage
https://www.readbyqxmd.com/read/28434754/-patient-safety-culture-in-family-practice-residents-of-galicia
#11
Manuel Portela Romero, Rosendo Bugarín González, María Sol Rodríguez Calvo
OBJECTIVE: To determine the views held by Family practice (FP) residents on the different dimensions of patient safety, in order to identify potential areas for improvement. DESIGN: A cross-sectional study. LOCATION: Seven FP of Galicia teaching units. PARTICIPANTS: 182 FP residents who completed the Medical Office Survey on Patient Safety Culture questionnaire. MEASUREMENTS: The Medical Office Survey on Patient Safety Culture questionnaire was chosen because it is translated, validated, and adapted to the Spanish model of Primary Care...
April 20, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28434722/prediction-of-milk-fatty-acid-content-with-mid-infrared-spectroscopy-in-canadian-dairy-cattle-using-differently-distributed-model-development-sets
#12
A Fleming, F S Schenkel, J Chen, F Malchiodi, V Bonfatti, R A Ali, B Mallard, M Corredig, F Miglior
The fatty acid profile of milk is a prevailing issue due to the potential negative or positive effects of different fatty acids to human health and nutrition. Mid-infrared spectroscopy can be used to obtain predictions of otherwise costly fatty acid phenotypes in a widespread and rapid manner. The objective of this study was to evaluate the prediction of fatty acid content for the Canadian dairy cattle population from mid-infrared spectral data and to compare the results produced by altering the partial least squares (PLS) model development set used...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28434095/patient-reported-outcomes-in-cancer-survivors-a-population-wide-cross-sectional-study
#13
Michael Jefford, Andrew C Ward, Karolina Lisy, Karen Lacey, Jon D Emery, Adam W Glaser, Hannah Cross, Mei Krishnasamy, Sue-Anne McLachlan, Jim Bishop
PURPOSE: There is a lack of robust population-based data regarding the lived experience of cancer survivors. This study assessed the quality of life (QoL) of survivors of breast, colorectal, or prostate cancer, non-Hodgkin lymphoma or melanoma 1, 3 and 5 years post-diagnosis. Associations between various demographic and disease-related factors and QoL were assessed. METHODS: A cross-sectional postal survey was undertaken. Eligible participants were identified from a population-based cancer registry...
April 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28433923/uhplc-q-orbitrap-hrms-based-global-metabolomics-reveal-metabolome-modifications-in-plasma-of-young-women-after-cranberry-juice-consumption
#14
Haiyan Liu, Timothy J Garrett, Zhihua Su, Christina Khoo, Liwei Gu
Plasma metabolome in young women following cranberry juice consumption were investigated using a global UHPLC-Q-Orbitrap-HRMS approach. Seventeen female college students, between 21 and 29 years old, were given either cranberry juice or apple juice for three days using a cross-over design. Plasma samples were collected before and after juice consumption. Plasma metabolomes were analyzed using UHPLC-Q-Orbitrap-HRMS followed by orthogonal partial least squares-discriminant analyses (OPLS-DA). S-plot was used to identify discriminant metabolites...
April 7, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28433831/ultrasonography-of-the-transverse-movement-and-deformation-of-the-median-nerve-and-its-relationships-with-electrophysiological-severity-in-the-early-stages-of-carpal-tunnel-syndrome
#15
Donghwi Park
BACKGROUND: To date, there have been conflicting suggestions regarding theinitial pathogenesis of CTS.It has been characterized as either inflammation of the median nerve caused by compression ornon-inflammatory fibrosis of the subsynovial connective tissue (SSCT). OBJECTIVE: To investigate the initialpathogenesis of CTS, we compared the deformation and displacement of the median nerve in accordance with the electrophysiological severity between patients with CTS (via Bland`s scale) and healthy controls...
April 19, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28433694/bacteroidales-markers-for-microbial-source-tracking-in-southeast-asia
#16
Jean Pierre Nshimyimana, Mercedes C Cruz, R Janelle Thompson, Stefan Wuertz
The island city country of Singapore served as a model to validate the use of host-associated Bacteroidales 16S rRNA gene marker assays for identifying sources of fecal pollution in the urban tropical environment of Southeast Asia. A total of 295 samples were collected from sewage, humans, domesticated animals (cats, dogs, rabbits and chicken), and wild animals (birds, monkeys and wild boars). Samples were analyzed by real time PCR using five human-associated assays (HF183-SYBR Green, HF183, BacHum, BacH and B...
April 10, 2017: Water Research
https://www.readbyqxmd.com/read/28432935/accelerometry-based-assessment-and-detection-of-early-signs-of-balance-deficits
#17
Heidi Similä, Milla Immonen, Miikka Ermes
Falls are the cause for more than half of the injury-related hospitalizations among older people. Accurate assessment of individuals' fall risk could enable targeted interventions to reduce the risk. This paper presents a novel method for using wearable accelerometers to detect early signs of deficits in balance from gait. Gait acceleration data were analyzed from 35 healthy female participants (73.86±5.40 years). The data were collected with waist-mounted accelerometer and the participants performed three supervised balance tests: Berg Balance Scale (BBS), Timed-Up-and-Go (TUG) and 4m walk...
April 13, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28432894/the-structure-correlates-and-treatment-related-changes-of-mindfulness-facets-across-the-anxiety-disorders-and-obsessive-compulsive-disorder
#18
Lance L Hawley, Jenny Rogojanski, Valerie Vorstenbosch, Lena C Quilty, Judith M Laposa, Neil A Rector
Research with non-clinical and clinical samples has examined how mindfulness concepts relate to psychological symptom presentations. However, there is less clarity when examining treatment-seeking patients who experience DSM-diagnosed anxiety and obsessional disorders - both cross-sectionally, and following empirically-supported treatments. The Five Facet Mindfulness Questionnaire (FFMQ; Baer, Smith, Hopkins, Krietemeyer, & Toney, 2006) conceptualizes mindfulness as consisting of five facets: Observing, Describing, Acting with Awareness, Nonreactivity, and Nonjudging...
March 14, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28432760/determination-of-ochratoxin-a-in-black-and-white-pepper-nutmeg-spice-mix-cocoa-and-drinking-chocolate-by-high-performance-liquid-chromatography-coupled-with-fluorescence-detection-collaborative-study
#19
Elena Cubero-Leon, Katrien Bouten, Hamide Senyuva, Joerg Stroka
A method validation study for the determination of ochratoxin A in black and white pepper (Piper spp.), nutmeg (Myristica fragrans), spice mix (blend of ginger, turmeric, pepper, nutmeg, and chili), cocoa powder, and drinking chocolate was conducted according to the International Harmonized Protocol of the International Union of Pure and Applied Chemistry. The method is based on the extraction of samples with aqueous methanol, followed by a cleanup of the extract with an immunoaffinity column. The determination is carried out by reversed-phase LC coupled with a fluorescence detector...
April 22, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28432524/correlation-of-serum-mmp3-and-other-biomarkers-with-clinical-outcomes-in-patients-with-ankylosing-spondylitis-a-pilot-study
#20
Dongyi He, Qi Zhu, Quan Zhou, Qing Qi, Hongmei Sun, Liza M Zachariah, Grace Wang, John D Reveille, Yongtao Guan, Xiaodong Zhou
The studies aimed to assess a set of biomarkers for their correlations with disease activity/severity of patients with ankylosing spondylitis (AS). A total of 24 AS patients were treated with etanercept and prospectively followed for 12 weeks. Serum levels of TNF-α, IFN-γ, TGF-β, IL6, IL15, IL17, MMP3, and MICA were measured at baseline and after treatment. The change of these biomarkers was analyzed for correlations with MRI indices for joint inflammation, Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing Spondylitis Functional Index, AS Disease Activity Score, serum CRP, and ESR...
April 22, 2017: Clinical Rheumatology
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